Chrnb1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Chrnb1
Entrez Gene ID	24261
Full Name	cholinergic receptor nicotinic beta 1 subunit
Synonyms	Acrb,RNACRB1,nAChR
General protein information	Preferred Names cholinergic receptor nicotinic beta 1 subunit Names acetylcholine receptor subunit beta Acetylcholine receptor beta cholinergic receptor nicotinic beta polypeptide 1 cholinergic receptor, nicotinic beta 1 cholinergic receptor, nicotinic, beta 1 (muscle) cholinergic receptor, nicotinic, beta polypeptide 1 (muscle) n acetylcholine receptor
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q24
Summary	beta subunit of the nicotinic acetylcholine receptor; can assemble into functionally different acetylcholine receptor channel subtypes [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_012528.1	NP_036660.1	acetylcholine receptor subunit beta precursor
XM_008767770.2	XP_008765992.1	acetylcholine receptor subunit beta isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CHRNB1	XP_511298.3
Danio rerio (zebrafish)	chrnb1	NP_001240739.1
Canis lupus familiaris (dog)	CHRNB1	XP_546591.2
Bos taurus (cattle)	CHRNB1	NP_776941.1
Mus musculus (house mouse)	Chrnb1	NP_033731.3
Homo sapiens (human)	CHRNB1	NP_000738.2
	CHRNB1	XP_001108848.2
Rattus norvegicus (Norway rat)	Chrnb1	NP_036660.1

Gene Ontology
Bibliography

Related articles in PubMed

The neuromuscular junction: selective remodeling of synaptic regulators at the nerve/muscle interface.
Witzemann V, Chevessier F, Pacifici PG, Yampolsky P
Mechanisms of development130(6-8)402-11(2013 Jun-Aug)

A novel mode-of-action mediated by the fetal muscle nicotinic acetylcholine receptor resulting in developmental toxicity in rats.
Rasoulpour RJ, Ellis-Hutchings RG, Terry C, Millar NS, Zablotny CL, Gibb A, Marshall V, Collins T, Carney EW, Billington R
Toxicological sciences : an official journal of the Society of Toxicology127(2)522-34(2012 Jun)

Mammalian nicotinic acetylcholine receptors: from structure to function.
Albuquerque EX, Pereira EF, Alkondon M, Rogers SW
Physiological reviews89(1)73-120(2009 Jan)

Gene-based analysis suggests association of the nicotinic acetylcholine receptor beta1 subunit (CHRNB1) and M1 muscarinic acetylcholine receptor (CHRM1) with vulnerability for nicotine dependence.
Lou XY, Ma JZ, Payne TJ, Beuten J, Crew KM, Li MD
Human genetics120(3)381-9(2006 Oct)

Rapsyn escorts the nicotinic acetylcholine receptor along the exocytic pathway via association with lipid rafts.
Marchand S, Devillers-Thi?ry A, Pons S, Changeux JP, Cartaud J
The Journal of neuroscience : the official journal of the Society for Neuroscience22(20)8891-901(2002 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Chrnb1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Chrnb1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00217	NM_012528.1 Latest version!	Rattus norvegicus cholinergic receptor nicotinic beta 1 subunit (Chrnb1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$293.30 $419.00
ORa42876	XM_008767770.2 Latest version!	Rattus norvegicus cholinergic receptor nicotinic beta 1 subunit (Chrnb1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Chrnb1 ( NM_012528.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_036660.1 Rattus norvegicus cholinergic receptor nicotinic beta 1 subunit (Chrnb1), mRNA.

Price & Availability↑

CloneID	ORa00217
Clone ID Related Accession (Same CDS sequence)	NM_012528.1
Accession Version	NM_012528.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1506bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	acetylcholine receptor subunit beta precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X74833.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X74833.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCCTTAG GGGCGCTGCT TCTGATTCTG GGGATACTCG GGACGCCCCT CGCCCCAGGA 
GCCCGCGGGT CGGAAGCCGA AGGCCAACTG CTTAAGAAAC TTTTCTCGGA TTATGATAGC 
TCAGTAAGGC CGGCGCAGGA GGTGGGAGAC CGCGTCGGGG TCAGCATCGG CCTCACCCTG 
GCGCAACTCA TCAGCCTGAA CGAGAAGGAT GAAGAAATGA GCACAAAGGT GTACTTAGAC 
CTGGAGTGGA CCGACTACAG GTTAAGCTGG GACCCCGCAG AACACGATGG CATCGAGTCT 
CTCCGTGTCA CTGCTGAATC TGTTTGGCTC CCGGACGTGG TGCTGCTGAA CAACAATGAT 
GGAAACTTTG ACGTTGCCCT GGACATTAAT GTCGTGGTGT CCTTTGAGGG CTCTGTGCGC 
TGGCAACCCC CTGGCCTGTA TCGCAGCAGC TGCAGCATCC AGGTCACCTA CTTCCCCTTT 
GACTGGCAGA ATTGCACCAT GGTGTTTAGT TCCTACAGCT ATGACAGCTC TGAGGTCAGC 
CTGAAGACAG GCCCAGATCC TGATGGACAG GAGAGGCAGG AAATCTACAT CCATGAAGGG 
ACCTTCATCG AGAATGGTCA ATGGGAGATT ATCCACAAAC CCTCTAGGTT AATCCACCTT 
CCAGGGGATC GAAGAGGAGG GAAGGAAGGA CATCGTGAGG AAGTTATCTT CTATCTCATT 
ATTCGGAGGA AGCCTCTCTT CTACCTGGTC AATGTCATTG CCCCGTGCAT CCTCATCACC 
CTCCTGGCCA TCTTTGTTTT CTACCTTCCA CCAGATGCAG GAGAGAAGAT GGGGCTCTCC 
ATCTTTGCCC TGCTGACCCT CACTGTGTTC TTGCTGCTGC TGGCCGACAA AGTGCCTGAG 
ACCTCCCTGG CGGTCCCCAT CATCATCAAG TATCTCATGT TTACCATGAT CCTTGTCACC 
TTCTCAGTTA TCCTTAGCGT TGTGGTCCTC AACTTGCACC ATCGCTCACC CCACACCCAC 
CAAATGCCCT TTTGGGTCCG CCAGATCTTC ATTCACAAGC TCCCTCCATA CCTGGGTCTG 
AAGAGGCCCA AACCCGAGAG AGACCAACTA CCCGAACCAC ATCACTCCTT CTCCCCAAGG 
AGTGGCTGGG GCCGAGGAAC TGATGAATAT TTCATACGGA AGCCTCCATG TGATTTTCTT 
TTCCCTAAAC TTAACAGGTT TCAGCCTGAA TCACCTGCTC CGGACCTGAG ACGATTTATC 
GATGGTCCAC CCCGGGCTGT AGGTCTGCCT CAGGAGCTAC GCGAGGTCAT TTCTTCCATC 
AGCTACATGG CCCGACAACT TCAGGAACAG GAGGACCACG ATGCACTGAA GGAGGACTGG 
CAGTTTGTCG CCATGGTTGT GGACCGTCTT TTTCTGTGGA CATTCATCGT TTTCACAAGC 
GTCGGGACGC TAGTCATTTT CCTAGATGCC ACGTACCATT TGCCCCCTCC TGAACCTTTT 
CCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036660.1
CDS	71..1576
Translation	MALGALLLILGILGTPLAPGARGSEAEGQLLKKLFSDYDSSVRPAQEVGDRVGVSIGLTLAQLISLNEKDEEMSTKVYLDLEWTDYRLSWDPAEHDGIESLRVTAESVWLPDVVLLNNNDGNFDVALDINVVVSFEGSVRWQPPGLYRSSCSIQVTYFPFDWQNCTMVFSSYSYDSSEVSLKTGPDPDGQERQEIYIHEGTFIENGQWEIIHKPSRLIHLPGDRRGGKEGHREEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYLPPDAGEKMGLSIFALLTLTVFLLLLADKVPETSLAVPIIIKYLMFTMILVTFSVILSVVVLNLHHRSPHTHQMPFWVRQIFIHKLPPYLGLKRPKPERDQLPEPHHSFSPRSGWGRGTDEYFIRKPPCDFLFPKLNRFQPESPAPDLRRFIDGPPRAVGLPQELREVISSISYMARQLQEQEDHDALKEDWQFVAMVVDRLFLWTFIVFTSVGTLVIFLDATYHLPPPEPFP

Target ORF information:

RefSeq Version	NM_012528.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cholinergic receptor nicotinic beta 1 subunit (Chrnb1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012528.1

ORF Insert Sequence:

ATGGCCTTAG GGGCGCTGCT TCTGATTCTG GGGATACTCG GGACGCCCCT CGCCCCAGGA 
GCCCGCGGGT CGGAAGCCGA AGGCCAACTG CTTAAGAAAC TTTTCTCGGA TTATGATAGC 
TCAGTAAGGC CGGCGCAGGA GGTGGGAGAC CGCGTCGGGG TCAGCATCGG CCTCACCCTG 
GCGCAACTCA TCAGCCTGAA CGAGAAGGAT GAAGAAATGA GCACAAAGGT GTACTTAGAC 
CTGGAGTGGA CCGACTACAG GTTAAGCTGG GACCCCGCAG AACACGATGG CATCGAGTCT 
CTCCGTGTCA CTGCTGAATC TGTTTGGCTC CCGGACGTGG TGCTGCTGAA CAACAATGAT 
GGAAACTTTG ACGTTGCCCT GGACATTAAT GTCGTGGTGT CCTTTGAGGG CTCTGTGCGC 
TGGCAACCCC CTGGCCTGTA TCGCAGCAGC TGCAGCATCC AGGTCACCTA CTTCCCCTTT 
GACTGGCAGA ATTGCACCAT GGTGTTTAGT TCCTACAGCT ATGACAGCTC TGAGGTCAGC 
CTGAAGACAG GCCCAGATCC TGATGGACAG GAGAGGCAGG AAATCTACAT CCATGAAGGG 
ACCTTCATCG AGAATGGTCA ATGGGAGATT ATCCACAAAC CCTCTAGGTT AATCCACCTT 
CCAGGGGATC GAAGAGGAGG GAAGGAAGGA CATCGTGAGG AAGTTATCTT CTATCTCATT 
ATTCGGAGGA AGCCTCTCTT CTACCTGGTC AATGTCATTG CCCCGTGCAT CCTCATCACC 
CTCCTGGCCA TCTTTGTTTT CTACCTTCCA CCAGATGCAG GAGAGAAGAT GGGGCTCTCC 
ATCTTTGCCC TGCTGACCCT CACTGTGTTC TTGCTGCTGC TGGCCGACAA AGTGCCTGAG 
ACCTCCCTGG CGGTCCCCAT CATCATCAAG TATCTCATGT TTACCATGAT CCTTGTCACC 
TTCTCAGTTA TCCTTAGCGT TGTGGTCCTC AACTTGCACC ATCGCTCACC CCACACCCAC 
CAAATGCCCT TTTGGGTCCG CCAGATCTTC ATTCACAAGC TCCCTCCATA CCTGGGTCTG 
AAGAGGCCCA AACCCGAGAG AGACCAACTA CCCGAACCAC ATCACTCCTT CTCCCCAAGG 
AGTGGCTGGG GCCGAGGAAC TGATGAATAT TTCATACGGA AGCCTCCATG TGATTTTCTT 
TTCCCTAAAC TTAACAGGTT TCAGCCTGAA TCACCTGCTC CGGACCTGAG ACGATTTATC 
GATGGTCCAC CCCGGGCTGT AGGTCTGCCT CAGGAGCTAC GCGAGGTCAT TTCTTCCATC 
AGCTACATGG CCCGACAACT TCAGGAACAG GAGGACCACG ATGCACTGAA GGAGGACTGG 
CAGTTTGTCG CCATGGTTGT GGACCGTCTT TTTCTGTGGA CATTCATCGT TTTCACAAGC 
GTCGGGACGC TAGTCATTTT CCTAGATGCC ACGTACCATT TGCCCCCTCC TGAACCTTTT 
CCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Chrnb1 ( XM_008767770.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008765992.1 Rattus norvegicus cholinergic receptor nicotinic beta 1 subunit (Chrnb1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa42876
Clone ID Related Accession (Same CDS sequence)	XM_008767770.2
Accession Version	XM_008767770.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1515bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	acetylcholine receptor subunit beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008767770.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCTTAG GGGCGCTGCT TCTGATTCTG GGGATACTCG GGACGCCCCT CGCCCCAGGA 
GCCCGCGGGT CGGAAGCCGA AGGCCAACTG CTTAAGAAAC TTTTCTCGGA TTATGATAGC 
TCAGTAAGGC CGGCGCAGGA GGTGGGAGAC CGCGTCGGGG TCAGCATCGG CCTCACCCTG 
GCGCAACTCA TCAGCCTGGT GAGAGAGAAC GAGAAGGATG AAGAAATGAG CACAAAGGTG 
TACTTAGACC TGGAGTGGAC CGACTACAGG TTAAGCTGGG ACCCCGCAGA ACACGATGGC 
ATCGAGTCTC TCCGTGTCAC TGCTGAATCT GTTTGGCTCC CGGACGTGGT GCTGCTGAAC 
AACAATGATG GAAACTTTGA CGTTGCCCTG GACATTAATG TCGTGGTGTC CTTTGAGGGC 
TCTGTGCGCT GGCAACCCCC TGGCCTGTAT CGCAGCAGCT GCAGCATCCA GGTCACCTAC 
TTCCCCTTTG ACTGGCAGAA TTGCACCATG GTGTTTAGTT CCTACAGCTA TGACAGCTCT 
GAGGTCAGCC TGAAGACAGG CCCAGATCCT GATGGACAGG AGAGGCAGGA AATCTACATC 
CATGAAGGGA CCTTCATCGA GAATGGTCAA TGGGAGATTA TCCACAAACC CTCTAGGTTA 
ATCCACCTTC CAGGGGATCG AAGAGGAGGG AAGGAAGGAC ATCGTGAGGA AGTTATCTTC 
TATCTCATTA TTCGGAGGAA GCCTCTCTTC TACCTGGTCA ATGTCATTGC CCCGTGCATC 
CTCATCACCC TCCTGGCCAT CTTTGTTTTC TACCTTCCAC CAGATGCAGG AGAGAAGATG 
GGGCTCTCCA TCTTTGCCCT GCTGACCCTC ACTGTGTTCT TGCTGCTGCT GGCCGACAAA 
GTGCCTGAGA CCTCCCTGGC GGTCCCCATC ATCATCAAGT ATCTCATGTT TACCATGATC 
CTTGTCACCT TCTCAGTTAT CCTTAGCGTT GTGGTCCTCA ACTTGCACCA TCGCTCACCC 
CACACCCACC AAATGCCCTT TTGGGTCCGC CAGATCTTCA TTCACAAGCT CCCTCCATAC 
CTGGGTCTGA AGAGGCCCAA ACCCGAGAGA GACCAACTAC CCGAACCACA TCACTCCTTC 
TCCCCAAGGA GTGGCTGGGG CCGAGGAACT GATGAATATT TCATACGGAA GCCTCCATGT 
GATTTTCTTT TCCCTAAACT TAACAGGTTT CAGCCTGAAT CACCTGCTCC GGACCTGAGA 
CGATTTATCG ATGGTCCACC CCGGGCTGTA GGTCTGCCTC AGGAGCTACG CGAGGTCATT 
TCTTCCATCA GCTACATGGC CCGACAACTT CAGGAACAGG AGGACCACGA TGCACTGAAG 
GAGGACTGGC AGTTTGTCGC CATGGTTGTG GACCGTCTTT TTCTGTGGAC ATTCATCGTT 
TTCACAAGCG TCGGGACGCT AGTCATTTTC CTAGATGCCA CGTACCATTT GCCCCCTCCT 
GAACCTTTTC CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008765992.1
CDS	138..1652
Translation	MALGALLLILGILGTPLAPGARGSEAEGQLLKKLFSDYDSSVRPAQEVGDRVGVSIGLTLAQLISLVRENEKDEEMSTKVYLDLEWTDYRLSWDPAEHDGIESLRVTAESVWLPDVVLLNNNDGNFDVALDINVVVSFEGSVRWQPPGLYRSSCSIQVTYFPFDWQNCTMVFSSYSYDSSEVSLKTGPDPDGQERQEIYIHEGTFIENGQWEIIHKPSRLIHLPGDRRGGKEGHREEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYLPPDAGEKMGLSIFALLTLTVFLLLLADKVPETSLAVPIIIKYLMFTMILVTFSVILSVVVLNLHHRSPHTHQMPFWVRQIFIHKLPPYLGLKRPKPERDQLPEPHHSFSPRSGWGRGTDEYFIRKPPCDFLFPKLNRFQPESPAPDLRRFIDGPPRAVGLPQELREVISSISYMARQLQEQEDHDALKEDWQFVAMVVDRLFLWTFIVFTSVGTLVIFLDATYHLPPPEPFP

Target ORF information:

RefSeq Version	XM_008767770.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cholinergic receptor nicotinic beta 1 subunit (Chrnb1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008767770.2

ORF Insert Sequence:

ATGGCCTTAG GGGCGCTGCT TCTGATTCTG GGGATACTCG GGACGCCCCT CGCCCCAGGA 
GCCCGCGGGT CGGAAGCCGA AGGCCAACTG CTTAAGAAAC TTTTCTCGGA TTATGATAGC 
TCAGTAAGGC CGGCGCAGGA GGTGGGAGAC CGCGTCGGGG TCAGCATCGG CCTCACCCTG 
GCGCAACTCA TCAGCCTGGT GAGAGAGAAC GAGAAGGATG AAGAAATGAG CACAAAGGTG 
TACTTAGACC TGGAGTGGAC CGACTACAGG TTAAGCTGGG ACCCCGCAGA ACACGATGGC 
ATCGAGTCTC TCCGTGTCAC TGCTGAATCT GTTTGGCTCC CGGACGTGGT GCTGCTGAAC 
AACAATGATG GAAACTTTGA CGTTGCCCTG GACATTAATG TCGTGGTGTC CTTTGAGGGC 
TCTGTGCGCT GGCAACCCCC TGGCCTGTAT CGCAGCAGCT GCAGCATCCA GGTCACCTAC 
TTCCCCTTTG ACTGGCAGAA TTGCACCATG GTGTTTAGTT CCTACAGCTA TGACAGCTCT 
GAGGTCAGCC TGAAGACAGG CCCAGATCCT GATGGACAGG AGAGGCAGGA AATCTACATC 
CATGAAGGGA CCTTCATCGA GAATGGTCAA TGGGAGATTA TCCACAAACC CTCTAGGTTA 
ATCCACCTTC CAGGGGATCG AAGAGGAGGG AAGGAAGGAC ATCGTGAGGA AGTTATCTTC 
TATCTCATTA TTCGGAGGAA GCCTCTCTTC TACCTGGTCA ATGTCATTGC CCCGTGCATC 
CTCATCACCC TCCTGGCCAT CTTTGTTTTC TACCTTCCAC CAGATGCAGG AGAGAAGATG 
GGGCTCTCCA TCTTTGCCCT GCTGACCCTC ACTGTGTTCT TGCTGCTGCT GGCCGACAAA 
GTGCCTGAGA CCTCCCTGGC GGTCCCCATC ATCATCAAGT ATCTCATGTT TACCATGATC 
CTTGTCACCT TCTCAGTTAT CCTTAGCGTT GTGGTCCTCA ACTTGCACCA TCGCTCACCC 
CACACCCACC AAATGCCCTT TTGGGTCCGC CAGATCTTCA TTCACAAGCT CCCTCCATAC 
CTGGGTCTGA AGAGGCCCAA ACCCGAGAGA GACCAACTAC CCGAACCACA TCACTCCTTC 
TCCCCAAGGA GTGGCTGGGG CCGAGGAACT GATGAATATT TCATACGGAA GCCTCCATGT 
GATTTTCTTT TCCCTAAACT TAACAGGTTT CAGCCTGAAT CACCTGCTCC GGACCTGAGA 
CGATTTATCG ATGGTCCACC CCGGGCTGTA GGTCTGCCTC AGGAGCTACG CGAGGTCATT 
TCTTCCATCA GCTACATGGC CCGACAACTT CAGGAACAGG AGGACCACGA TGCACTGAAG 
GAGGACTGGC AGTTTGTCGC CATGGTTGTG GACCGTCTTT TTCTGTGGAC ATTCATCGTT 
TTCACAAGCG TCGGGACGCT AGTCATTTTC CTAGATGCCA CGTACCATTT GCCCCCTCCT 
GAACCTTTTC CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The neuromuscular junction: selective remodeling of synaptic regulators at the nerve/muscle interface.
Mechanisms of development130(6-8)402-11(2013 Jun-Aug)
Witzemann V,Chevessier F,Pacifici PG,Yampolsky P

A novel mode-of-action mediated by the fetal muscle nicotinic acetylcholine receptor resulting in developmental toxicity in rats.
Toxicological sciences : an official journal of the Society of Toxicology127(2)522-34(2012 Jun)
Rasoulpour RJ,Ellis-Hutchings RG,Terry C,Millar NS,Zablotny CL,Gibb A,Marshall V,Collins T,Carney EW,Billington R

Mammalian nicotinic acetylcholine receptors: from structure to function.
Physiological reviews89(1)73-120(2009 Jan)
Albuquerque EX,Pereira EF,Alkondon M,Rogers SW

Gene-based analysis suggests association of the nicotinic acetylcholine receptor beta1 subunit (CHRNB1) and M1 muscarinic acetylcholine receptor (CHRM1) with vulnerability for nicotine dependence.
Human genetics120(3)381-9(2006 Oct)
Lou XY,Ma JZ,Payne TJ,Beuten J,Crew KM,Li MD

Rapsyn escorts the nicotinic acetylcholine receptor along the exocytic pathway via association with lipid rafts.
The Journal of neuroscience : the official journal of the Society for Neuroscience22(20)8891-901(2002 Oct)
Marchand S,Devillers-Thi?ry A,Pons S,Changeux JP,Cartaud J

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Chrnb1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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