Pcdha3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pcdha3
Entrez Gene ID	116780
Full Name	protocadherin alpha 3
General protein information	Preferred Names protocadherin alpha 3 Names protocadherin alpha-3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 18 Map Location: 18p11
Summary	may play a role in cell-cell adhesion during spermatogenesis [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_053941.1	NP_446393.1	protocadherin alpha-3 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Pcdha3	NP_619603.1
Rattus norvegicus (Norway rat)	Pcdha3	NP_446393.1
Pan troglodytes (chimpanzee)	PCDHA3	NP_001076055.1
Canis lupus familiaris (dog)	PCDHA3	XP_005617958.1
Homo sapiens (human)	PCDHA3	NP_061729.1

Gene Ontology
Bibliography

Related articles in PubMed

Sequence analysis and expression mapping of the rat clustered protocadherin gene repertoires.
Zou C, Huang W, Ying G, Wu Q
Neuroscience144(2)579-603(2007 Jan)

Comparative genomics and diversifying selection of the clustered vertebrate protocadherin genes.
Wu Q
Genetics169(4)2179-88(2005 Apr)

Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha.
Murata Y, Hamada S, Morishita H, Mutoh T, Yagi T
The Journal of biological chemistry279(47)49508-16(2004 Nov)

Genomic sequence and organization of the family of CNR/Pcdhalpha genes in rat.
Yanase H, Sugino H, Yagi T
Genomics83(4)717-26(2004 Apr)

Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.
Zhang T, Haws P, Wu Q
Genome research14(1)79-89(2004 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

protocadherin alpha3 performs functions unique from classic cadherins in spermatogenesis and suggest a role for protocadherin alpha3 in organizing germ cell-specific structures including the intercellular bridge, flagellum, and acrosome.
Title: Protocadherin alpha3 acts at sites distinct from classic cadherins in rat testis and sperm.

The following Pcdha3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pcdha3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa11120	NM_053941.1 Latest version!	Rattus norvegicus protocadherin alpha 3 (Pcdha3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pcdha3 ( NM_053941.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_446393.1 Rattus norvegicus protocadherin alpha 3 (Pcdha3), mRNA.

Price & Availability↑

CloneID	ORa11120
Clone ID Related Accession (Same CDS sequence)	NM_053941.1
Accession Version	NM_053941.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2829bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Rattus norvegicus(Norway rat)
Product	protocadherin alpha-3 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB113386.1. ##Evidence-Data-START## Transcript exon combination :: AB113386.1, AY573977.1 [ECO:0000332] ##Evidence-Data-END##

ATGGTGTTTT CTTGGAGAAA AGATCGGCGT CTGCTGCTCT GGCTTCTTCT CTTCTCAGCC 
TGGGAGGCAG GGAGCGGCCA GCTCCATTAC TCCGTCCCAG AGGAGGCCAA ACACGGCACC 
TTCGTGGGCC GCATCGCGCA GGACCTGGGG CTGGAGCTGG CGGAGCTGGT GCCCCGCCTG 
TTCAGGGTGG CGTCCAAGGA CCGCGGGGAT CTTCTGGAGG TAAATCTGCA GAATGGCATT 
TTGTTTGTGA ATTCTCGGAT CGACCGGGAG GAGCTGTGCG GGAGGAGTGC GGAGTGTAGC 
ATCCACTTGG AGGTGATCGT GGACAGGCCG CTGCAGGTTT TCCACGTGGA GGTAGAGGTG 
AGGGACATTA ACGACAACCC GCCAGTATTT CCAGCGGCCT CCAAGAATCT GTTTATTTCT 
GAATCTCGAC AGCTTGGCTC CCGATTTTCG CTAGAGGGCG CATCAGATGC AGACATCGGA 
ACAAATTCGT TATTGTCTTA CAGTCTTAAC TCCAGTGAGT ATTTTTCTTT GGACGTCAAA 
AGAAAAGACG AGGAAATTAG ATCTCTGGGA CTGGTGTTGA AAAAACTTTT AAACCGAGAG 
GATATTTCTG AACATCATTT ATTGATAACG GCAGTTGATG GTGGGAAACC TGAGCTCACT 
GGCAGCACTC AAGTGAAAAT CACTGTCCTA GATGTGAACG ACAACGCCCC AGCATTTGAG 
AAGACACTCT ACAAGGTCAG ATTGCCCGAA AATGCTCCAA ATGGAACTGT AGTTGTGGAT 
GTTGACGCCA CTGATTTGGA TGAAGGAGTA AATAAGGACA TTGTATATTC TTTTCACCCG 
GATATGTCAG CTGAGATCCT GTCAAAATTC CACTTAGACC CGGTCAATGG ATACATCACT 
GTGAAAGGCA ACATAGATTT TGAGGAAACC AAATCTTTTG AAATCCAGAT AGAGGCAGCA 
GACCAGGGAA CTCCCCCAAT GACAGATCAC TGCACGGTTC TAGTTGAAAT TGTGGACCTC 
AATGATAATG CGCCTGAATT GGTCATCAAG TCACTATCAC TTCCTGTGTT AGAAAGTTCT 
GCGCCTGGCA CTGTCATCGC CCTGATCAGT GTGTCCGACC GTGACTCTGG AGCCAACGGA 
CAGGTGACCT GCTCTCTGAG CCCTCAAGTC CCCTTCAAGC TGGTGTCCAG CTTCAAGAAT 
TACTATTCAC TCGTGCTGGA CAGCCCTTTG GACCGAGAGA CTATCGCTAA CTATGACGTG 
GTTGTGACTG CCAGGGACGG GGGCTCGCTC TCTCTGTGGG CTACTGCCAG CGTGTCCGTG 
GAGGTGGCTG ATGTGAACGA CAATGCGCCC CTGTTTGCTC AGCCTGAATA CACAGTGTTT 
GTGAAGGAGA ACAATCCACC AGGTACGCAT ATCTTCACGG TGTTTGCGGT GGATGCAGAT 
GCACAAGAGA ATGCATTGGT GTCCTACTCG CTGGTGGAGC GGAGGGTGGG CGAGCGCTTG 
CTGTCGAGCT ATGTGTCTGT GCACGCGGAG AGCGGCAAGG TGTTCGCACT GCAGCCTCTG 
GACCATGAGG AGCTGGAGCT GCTGCAGTTC CAGGTGAGCG CGCGGGATGC TGGTGTGCCT 
GCCCTGGGCA GCAATGTGAC TCTGCAGGTG TTTGTGCTGG ATGAGAACGA CAATGCGCCC 
ACACTGCTGG GGCCTCAAGC AGGCAGTGCA GTGAGCGAAC TGGTGTCACG GACAGTGAGT 
TCAGGACACG TGGTGACAAA GGTGCGCGCG GTGGATGCAG ACTCTGGCTA CAATGCGTGG 
CTCTCTTATG AGCTGCAGTC GGCAGCGGGC AGTGGACGTC TTCCCTTCCG CGTGGGTCTG 
TACACTGGTG AGATCAGCAC CACACGTGTC CTGGATGAAA CAGATGCCCC GCGACAGCGC 
CTATTAGTGT TGGTGAGGGA CCATGGCGAG CCGGTGCTGA CAGCAACAGC CACCTTGCTG 
GTGTCTTTGG TGGAGAGTGG ACACATGCCA AACACCCCAT CCCGGGCCTT GGTGGATTCT 
GCGGGCAGGG AGGCTTCACT TGTAGATATT AACGTGTACC TGATCATCGC CATCTGTGCC 
GTGTCTAGCC TGCTGGTGCT CACGCTGCTG CTGTATGTTG CACTTAGATG CTCCACAGCG 
CCTGCAGAGG GCGGGCCTGG GAAGCCTATG CTGGTGTGCT CCAGCGCGGT GGGTACCTGG 
TCTTACTCGC AGCAGAGAAG ACAGAGGGTG TGCTCTGGAG AGGGCCCACC GAAGACCGAC 
CTCATGGCCT TTAGCCCAAG TCTTACACCC TGCCCAGTTA ATCAAGATAA AGAGGACAAA 
CTGGTTGGAG ACATCGATTT CTCCGTCAAA CCCCGACAGC CCAACCCTGA CTGGCGCTAC 
TCTGCCTCGC TAAGAGCCGG CATGCACAGC TCTGTGCACC TGGAGGAGGC TGGCATTCTA 
CGGGCTGGTC CAGGAGGGCC TGATCAACAG TGGCCAACAG TATCCAGTGC AACACCAGAA 
CCAGAGGCAG GAGAGGTGTC CCCTCCAGTG GGCGCTGGTG TCAACAGCAA CAGCTGGACC 
TTTAAATACG GACCCGGCAA CCCCAAACAG CCCGGTCCCG GTGAGTTGCC AGACAAATTC 
ATTATCCCAG GATCTCCTGC AATCATCTCC ATCCGGCAGG AGTCTGCTAA CAACCAAATT 
GACAAAAGCG ATTTTATAAC CTTCGGCAAA AAGGAGGAGA CCAAGAAAAA GAAGAAAAAG 
AAGAAGGGTA ACAAGACCCA GGAGAAAAAA GAGAAAGGGA ACAGCACGAC GGACAACAGT 
GACCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_446393.1
CDS	1..2829
Translation	MVFSWRKDRRLLLWLLLFSAWEAGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKDRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVRDINDNPPVFPAASKNLFISESRQLGSRFSLEGASDADIGTNSLLSYSLNSSEYFSLDVKRKDEEIRSLGLVLKKLLNREDISEHHLLITAVDGGKPELTGSTQVKITVLDVNDNAPAFEKTLYKVRLPENAPNGTVVVDVDATDLDEGVNKDIVYSFHPDMSAEILSKFHLDPVNGYITVKGNIDFEETKSFEIQIEAADQGTPPMTDHCTVLVEIVDLNDNAPELVIKSLSLPVLESSAPGTVIALISVSDRDSGANGQVTCSLSPQVPFKLVSSFKNYYSLVLDSPLDRETIANYDVVVTARDGGSLSLWATASVSVEVADVNDNAPLFAQPEYTVFVKENNPPGTHIFTVFAVDADAQENALVSYSLVERRVGERLLSSYVSVHAESGKVFALQPLDHEELELLQFQVSARDAGVPALGSNVTLQVFVLDENDNAPTLLGPQAGSAVSELVSRTVSSGHVVTKVRAVDADSGYNAWLSYELQSAAGSGRLPFRVGLYTGEISTTRVLDETDAPRQRLLVLVRDHGEPVLTATATLLVSLVESGHMPNTPSRALVDSAGREASLVDINVYLIIAICAVSSLLVLTLLLYVALRCSTAPAEGGPGKPMLVCSSAVGTWSYSQQRRQRVCSGEGPPKTDLMAFSPSLTPCPVNQDKEDKLVGDIDFSVKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQPGPGELPDKFIIPGSPAIISIRQESANNQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ

Target ORF information:

RefSeq Version	NM_053941.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus protocadherin alpha 3 (Pcdha3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053941.1

ORF Insert Sequence:

ATGGTGTTTT CTTGGAGAAA AGATCGGCGT CTGCTGCTCT GGCTTCTTCT CTTCTCAGCC 
TGGGAGGCAG GGAGCGGCCA GCTCCATTAC TCCGTCCCAG AGGAGGCCAA ACACGGCACC 
TTCGTGGGCC GCATCGCGCA GGACCTGGGG CTGGAGCTGG CGGAGCTGGT GCCCCGCCTG 
TTCAGGGTGG CGTCCAAGGA CCGCGGGGAT CTTCTGGAGG TAAATCTGCA GAATGGCATT 
TTGTTTGTGA ATTCTCGGAT CGACCGGGAG GAGCTGTGCG GGAGGAGTGC GGAGTGTAGC 
ATCCACTTGG AGGTGATCGT GGACAGGCCG CTGCAGGTTT TCCACGTGGA GGTAGAGGTG 
AGGGACATTA ACGACAACCC GCCAGTATTT CCAGCGGCCT CCAAGAATCT GTTTATTTCT 
GAATCTCGAC AGCTTGGCTC CCGATTTTCG CTAGAGGGCG CATCAGATGC AGACATCGGA 
ACAAATTCGT TATTGTCTTA CAGTCTTAAC TCCAGTGAGT ATTTTTCTTT GGACGTCAAA 
AGAAAAGACG AGGAAATTAG ATCTCTGGGA CTGGTGTTGA AAAAACTTTT AAACCGAGAG 
GATATTTCTG AACATCATTT ATTGATAACG GCAGTTGATG GTGGGAAACC TGAGCTCACT 
GGCAGCACTC AAGTGAAAAT CACTGTCCTA GATGTGAACG ACAACGCCCC AGCATTTGAG 
AAGACACTCT ACAAGGTCAG ATTGCCCGAA AATGCTCCAA ATGGAACTGT AGTTGTGGAT 
GTTGACGCCA CTGATTTGGA TGAAGGAGTA AATAAGGACA TTGTATATTC TTTTCACCCG 
GATATGTCAG CTGAGATCCT GTCAAAATTC CACTTAGACC CGGTCAATGG ATACATCACT 
GTGAAAGGCA ACATAGATTT TGAGGAAACC AAATCTTTTG AAATCCAGAT AGAGGCAGCA 
GACCAGGGAA CTCCCCCAAT GACAGATCAC TGCACGGTTC TAGTTGAAAT TGTGGACCTC 
AATGATAATG CGCCTGAATT GGTCATCAAG TCACTATCAC TTCCTGTGTT AGAAAGTTCT 
GCGCCTGGCA CTGTCATCGC CCTGATCAGT GTGTCCGACC GTGACTCTGG AGCCAACGGA 
CAGGTGACCT GCTCTCTGAG CCCTCAAGTC CCCTTCAAGC TGGTGTCCAG CTTCAAGAAT 
TACTATTCAC TCGTGCTGGA CAGCCCTTTG GACCGAGAGA CTATCGCTAA CTATGACGTG 
GTTGTGACTG CCAGGGACGG GGGCTCGCTC TCTCTGTGGG CTACTGCCAG CGTGTCCGTG 
GAGGTGGCTG ATGTGAACGA CAATGCGCCC CTGTTTGCTC AGCCTGAATA CACAGTGTTT 
GTGAAGGAGA ACAATCCACC AGGTACGCAT ATCTTCACGG TGTTTGCGGT GGATGCAGAT 
GCACAAGAGA ATGCATTGGT GTCCTACTCG CTGGTGGAGC GGAGGGTGGG CGAGCGCTTG 
CTGTCGAGCT ATGTGTCTGT GCACGCGGAG AGCGGCAAGG TGTTCGCACT GCAGCCTCTG 
GACCATGAGG AGCTGGAGCT GCTGCAGTTC CAGGTGAGCG CGCGGGATGC TGGTGTGCCT 
GCCCTGGGCA GCAATGTGAC TCTGCAGGTG TTTGTGCTGG ATGAGAACGA CAATGCGCCC 
ACACTGCTGG GGCCTCAAGC AGGCAGTGCA GTGAGCGAAC TGGTGTCACG GACAGTGAGT 
TCAGGACACG TGGTGACAAA GGTGCGCGCG GTGGATGCAG ACTCTGGCTA CAATGCGTGG 
CTCTCTTATG AGCTGCAGTC GGCAGCGGGC AGTGGACGTC TTCCCTTCCG CGTGGGTCTG 
TACACTGGTG AGATCAGCAC CACACGTGTC CTGGATGAAA CAGATGCCCC GCGACAGCGC 
CTATTAGTGT TGGTGAGGGA CCATGGCGAG CCGGTGCTGA CAGCAACAGC CACCTTGCTG 
GTGTCTTTGG TGGAGAGTGG ACACATGCCA AACACCCCAT CCCGGGCCTT GGTGGATTCT 
GCGGGCAGGG AGGCTTCACT TGTAGATATT AACGTGTACC TGATCATCGC CATCTGTGCC 
GTGTCTAGCC TGCTGGTGCT CACGCTGCTG CTGTATGTTG CACTTAGATG CTCCACAGCG 
CCTGCAGAGG GCGGGCCTGG GAAGCCTATG CTGGTGTGCT CCAGCGCGGT GGGTACCTGG 
TCTTACTCGC AGCAGAGAAG ACAGAGGGTG TGCTCTGGAG AGGGCCCACC GAAGACCGAC 
CTCATGGCCT TTAGCCCAAG TCTTACACCC TGCCCAGTTA ATCAAGATAA AGAGGACAAA 
CTGGTTGGAG ACATCGATTT CTCCGTCAAA CCCCGACAGC CCAACCCTGA CTGGCGCTAC 
TCTGCCTCGC TAAGAGCCGG CATGCACAGC TCTGTGCACC TGGAGGAGGC TGGCATTCTA 
CGGGCTGGTC CAGGAGGGCC TGATCAACAG TGGCCAACAG TATCCAGTGC AACACCAGAA 
CCAGAGGCAG GAGAGGTGTC CCCTCCAGTG GGCGCTGGTG TCAACAGCAA CAGCTGGACC 
TTTAAATACG GACCCGGCAA CCCCAAACAG CCCGGTCCCG GTGAGTTGCC AGACAAATTC 
ATTATCCCAG GATCTCCTGC AATCATCTCC ATCCGGCAGG AGTCTGCTAA CAACCAAATT 
GACAAAAGCG ATTTTATAAC CTTCGGCAAA AAGGAGGAGA CCAAGAAAAA GAAGAAAAAG 
AAGAAGGGTA ACAAGACCCA GGAGAAAAAA GAGAAAGGGA ACAGCACGAC GGACAACAGT 
GACCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Sequence analysis and expression mapping of the rat clustered protocadherin gene repertoires.
Neuroscience144(2)579-603(2007 Jan)
Zou C,Huang W,Ying G,Wu Q

Comparative genomics and diversifying selection of the clustered vertebrate protocadherin genes.
Genetics169(4)2179-88(2005 Apr)
Wu Q

Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha.
The Journal of biological chemistry279(47)49508-16(2004 Nov)
Murata Y,Hamada S,Morishita H,Mutoh T,Yagi T

Genomic sequence and organization of the family of CNR/Pcdhalpha genes in rat.
Genomics83(4)717-26(2004 Apr)
Yanase H,Sugino H,Yagi T

Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.
Genome research14(1)79-89(2004 Jan)
Zhang T,Haws P,Wu Q

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Pcdha3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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