PCDHA3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PCDHA3
Entrez Gene ID	56145
Full Name	protocadherin alpha 3
Synonyms	PCDH-ALPHA3
General protein information	Preferred Names protocadherin alpha 3 Names protocadherin alpha-3 KIAA0345-like 11 PCDH-alpha-3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q31.3
Summary	This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008].
Disorder MIM:	606309

mRNA and Protein(s)

mRNA	Protein	Name
NM_018906.2	NP_061729.1	protocadherin alpha-3 isoform 1 precursor
NM_018906.3	NP_061729.1	protocadherin alpha-3 isoform 1 precursor
NM_031497.1	NP_113685.1	protocadherin alpha-3 isoform 2 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Pcdha3	NP_619603.1
Rattus norvegicus (Norway rat)	Pcdha3	NP_446393.1
Pan troglodytes (chimpanzee)	PCDHA3	NP_001076055.1
Canis lupus familiaris (dog)	PCDHA3	XP_005617958.1
Homo sapiens (human)	PCDHA3	NP_061729.1

Gene Ontology
Bibliography

Related articles in PubMed

Exome sequencing in a family with restless legs syndrome.
Weissbach A, Siegesmund K, Br?ggemann N, Schmidt A, Kasten M, Pichler I, Muhle H, Lohmann E, Lohnau T, Schwinger E, Hagenah J, Stephani U, Pramstaller PP, Klein C, Lohmann K
Movement disorders : official journal of the Movement Disorder Society27(13)1686-9(2012 Nov)

Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.
Fox CS, Liu Y, White CC, Feitosa M, Smith AV, Heard-Costa N, Lohman K, , , , Johnson AD, Foster MC, Greenawalt DM, Griffin P, Ding J, Newman AB, Tylavsky F, Miljkovic I, Kritchevsky SB, Launer L, Garcia M, Eiriksdottir G, Carr JJ, Gudnason V, Harris TB, Cupples LA, Borecki IB
PLoS genetics8(5)e1002695(2012)

Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence.
Greg?rio SP, Sallet PC, Do KA, Lin E, Gattaz WF, Dias-Neto E
Psychiatry research165(1-2)1-9(2009 Jan)

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.
Wu C, Ma MH, Brown KR, Geisler M, Li L, Tzeng E, Jia CY, Jurisica I, Li SS
Proteomics7(11)1775-85(2007 Jun)

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.
Wu Q, Zhang T, Cheng JF, Kim Y, Grimwood J, Schmutz J, Dickson M, Noonan JP, Zhang MQ, Myers RM, Maniatis T
Genome research11(3)389-404(2001 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study suggested that PCDHA3 as a candidate gene for restless legs syndrome.
Title: Exome sequencing in a family with restless legs syndrome.

Observational study of gene-disease association. (HuGE Navigator)
Title: Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence.

The following PCDHA3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PCDHA3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29287	NM_031497.1 Latest version!	Homo sapiens protocadherin alpha 3 (PCDHA3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$580.30 $829.00
OHu29341	NM_018906.3 Latest version!	Homo sapiens protocadherin alpha 3 (PCDHA3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$657.30 $939.00
View Old Accession Versions >>
OHu29341	NM_018906.2	Homo sapiens protocadherin alpha 3 (PCDHA3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$657.30 $939.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PCDHA3 ( NM_031497.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_113685.1 Homo sapiens protocadherin alpha 3 (PCDHA3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu29287
Clone ID Related Accession (Same CDS sequence)	NM_031497.1
Accession Version	NM_031497.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2475bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-03
Organism	Homo sapiens(human)
Product	protocadherin alpha-3 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF152481.1. Transcript Variant: This variant (2) utilizes the large, first exon then continues into the downstream intron 1 sequence before terminating. This one-exon transcript encodes a shorter isoform (2), compared to isoform 1. This short variant is represented based on data in PMID:10380929. ##Evidence-Data-START## Transcript is intronless :: BC129807.1, AF152481.1 [ECO:0000345] ##Evidence-Data-END##

ATGTTGTTCT CCTGGCGAGA AGATCCTGGA GCCCAGTGCC TGCTGCTTTC TCTTCTGCTC 
CTCGCAGCCT CGGAGGTGGG GAGCGGCCAG CTCCACTACT CCGTCTCTGA GGAGGCCAAG 
CATGGCACCT TCGTGGGCCG CATCGCGCAG GACCTGGGGC TGGAGCTGGC GGAGCTGGTG 
CCGCGCCTGT TCCGGGTGGC GTCCAAAAGA CACGGGGACC TTCTGGAGGT AAATCTGCAG 
AATGGCATTT TGTTTGTGAA TTCTCGGATA GACCGCGAGG AACTGTGCGG GCGGAGCGCG 
GAGTGCAGCA TCCACCTGGA GGTGATCGTG GACAGGCCGC TGCAGGTTTT CCATGTGGAG 
GTGGAAGTGA AGGACATTAA TGACAACGCG CCAGTTTTTC CAATGGCTGT AAAGAATCTG 
TTTATTTCCG AATCCCGACA GCCTGGCTCT CGGTTTTCGC TAGAGGGCGC ATCAGATGCA 
GATATCGGAA CAAATTCGTT GTTGACTTAC AGTCTTGATT CCACTGAATA TTTTACCTTG 
GACGTTAAAA GAAATGATGA GGAAATTAAA TCCCTTGGAC TCGTGTTGAA AAAAAATTTA 
AATCGAGAGG ACACTCCTAA GCATTATTTA CTAATAACAG CAATTGATGG TGGGAAACCA 
GAGCTCACTG GCACGACTCA ACTAAAGATC ACTGTTTTAG ATGTAAACGA CAACGCCCCA 
GCGTTTGAGA GGACGATCTA TAAAGTCAGA TTACTCGAAA ATGCACCAAA TGGTACCCTA 
GTGGTGACCG TTAACGCCAC CGATTTGGAT GAAGGAGTAA ATAAGGATAT CGCGTATTCT 
TTCAATACGG ACATGTCAGC AGATATTCTG TCAAAATTCC ATTTAGATCC AGTCAATGGA 
CAAATCAGTG TAAAGGGTAA CATAGATTTC GAGGAAAGTA AGTCATATGA AATCCAGGTA 
GAAGCCACGG ATAAAGGAAA TCCCCCAATG TCAGATCACT GCACAGTTCT ACTCGAAATT 
GTGGACATCA ATGATAATGT ACCTGAGTTA GTTATTCAAT CACTATCTTT ACCTGTATTA 
GAAGACTCTC CACTTAGCAC AGTCATCGCT CTGATCAGCG TGTCCGACCG CGACTCAGGA 
GTCAATGGAC AGGTCACCTG CTCGCTGACG CCCCACGTCC CCTTCAAGCT GGTGTCCACC 
TTCAAGAATT ACTACTCATT GGTGCTGGAC AGCCCTCTGG ACCGCGAGAG CGTGTCGGCC 
TATGAGCTGG TGGTGACTGC TCGGGACGGG GGCTCGCCTT CACTGTGGGC CACGGCCAGC 
GTGTCCGTGG AGGTGGCCGA CGTGAACGAC AATGCGCCGG CATTCTCGCA GTCCGAGTAC 
ACGGTGTTCG TGAAGGAGAA CAACCCGCCG GGCTGCCACA TCTTCACGGT GTCTGCGCGG 
GACGCGGACG CGCAGGAGAA CGCCCTGGTG TCCTACTCGC TGGTGGAACG GCGGGTGGGG 
GAGCGCGCGC TGTCGAGCTA CGTGTCGGTA CACGCGGAGA GCGGCAAGGT GTACGCGCTG 
CAGCCGCTGG ACCACGAGGA GCTAGAGCTG CTGCAGTTCC AGGTGAGTGC GCGCGATGCG 
GGCGTGCCGC CTCTGGGCAG CAACGTGACG CTGCAGGTGT TCGTGCTGGA CGAGAACGAC 
AACGCGCCGG CACTGCTGAT GCCTCGGGTG GGTGGCATCG GTGGCGCAGT GAGCGAGCTG 
GTGCCGCGGT CAGTGGGTGC GGGCCACGTG GTAGCGAAGG TGCGCGCAGT GGATGCAGAC 
TCAGGCTACA ACGCGTGGCT TTCGTATGAG CTGCAGCCTG GGACCGGCGG TGCGCGCATC 
CCGTTTCGCG TGGGGCTGTA CACGGGAGAG ATCAGCACGA CCCGTGCCCT GGACGAGGTG 
GACGCCCCGC GCCATCGCCT ACTGGTGCTG GTGAAGGACC ACGGTGAACC CTCATTGACC 
GCCACGGCCA CTGTGCTGGT GTCGCTGGTG GAGAGTGGCC AGGCACCCAA GGCCTCGTCC 
CAGGCGTCCG CTGGCGCCAC GGGCCCGGAA GCTGCACTGG TGGATGTCAA CGTGTACTTG 
ATCGTCGCCA TCTGCGCGGT GTCCAGTCTG TTGGTGCTCA CACTGCTGCT ATATACTGCT 
CTGCGGTGCT CCGCGCCGCC AACCGAAGGC GACTGTGGGC CGGGCAAGCC CACGCTGGTG 
TGCTCCAGCG CGGTGGGGAG CTGGTCATAC TCGCAGCAGA GGCAGCAGAG GGTGTGCTCT 
GGAGAGGGGT TGCCCAAGAC CGACCTCATG GCTTTTAGCC CTAGCCTTCC TCCTTGTCCA 
ATTAGCCGGG ATAGAGAGGA GAAACAGGAT GTGGACGTTG ATCTCTCAGC CAAAGTGAGT 
AATTTTTATT TATTCTTTCC AAAATGTCTT TGTTTTTCAT TCCTCAATGT TTCCACTCCT 
CTGGAAATAC ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113685.1
CDS	1..2475
Translation	MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCPISRDREEKQDVDVDLSAKVSNFYLFFPKCLCFSFLNVSTPLEIH

Target ORF information:

RefSeq Version	NM_031497.1
Organism	Homo sapiens(human)
Definition	Homo sapiens protocadherin alpha 3 (PCDHA3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031497.1

ORF Insert Sequence:

ATGTTGTTCT CCTGGCGAGA AGATCCTGGA GCCCAGTGCC TGCTGCTTTC TCTTCTGCTC 
CTCGCAGCCT CGGAGGTGGG GAGCGGCCAG CTCCACTACT CCGTCTCTGA GGAGGCCAAG 
CATGGCACCT TCGTGGGCCG CATCGCGCAG GACCTGGGGC TGGAGCTGGC GGAGCTGGTG 
CCGCGCCTGT TCCGGGTGGC GTCCAAAAGA CACGGGGACC TTCTGGAGGT AAATCTGCAG 
AATGGCATTT TGTTTGTGAA TTCTCGGATA GACCGCGAGG AACTGTGCGG GCGGAGCGCG 
GAGTGCAGCA TCCACCTGGA GGTGATCGTG GACAGGCCGC TGCAGGTTTT CCATGTGGAG 
GTGGAAGTGA AGGACATTAA TGACAACGCG CCAGTTTTTC CAATGGCTGT AAAGAATCTG 
TTTATTTCCG AATCCCGACA GCCTGGCTCT CGGTTTTCGC TAGAGGGCGC ATCAGATGCA 
GATATCGGAA CAAATTCGTT GTTGACTTAC AGTCTTGATT CCACTGAATA TTTTACCTTG 
GACGTTAAAA GAAATGATGA GGAAATTAAA TCCCTTGGAC TCGTGTTGAA AAAAAATTTA 
AATCGAGAGG ACACTCCTAA GCATTATTTA CTAATAACAG CAATTGATGG TGGGAAACCA 
GAGCTCACTG GCACGACTCA ACTAAAGATC ACTGTTTTAG ATGTAAACGA CAACGCCCCA 
GCGTTTGAGA GGACGATCTA TAAAGTCAGA TTACTCGAAA ATGCACCAAA TGGTACCCTA 
GTGGTGACCG TTAACGCCAC CGATTTGGAT GAAGGAGTAA ATAAGGATAT CGCGTATTCT 
TTCAATACGG ACATGTCAGC AGATATTCTG TCAAAATTCC ATTTAGATCC AGTCAATGGA 
CAAATCAGTG TAAAGGGTAA CATAGATTTC GAGGAAAGTA AGTCATATGA AATCCAGGTA 
GAAGCCACGG ATAAAGGAAA TCCCCCAATG TCAGATCACT GCACAGTTCT ACTCGAAATT 
GTGGACATCA ATGATAATGT ACCTGAGTTA GTTATTCAAT CACTATCTTT ACCTGTATTA 
GAAGACTCTC CACTTAGCAC AGTCATCGCT CTGATCAGCG TGTCCGACCG CGACTCAGGA 
GTCAATGGAC AGGTCACCTG CTCGCTGACG CCCCACGTCC CCTTCAAGCT GGTGTCCACC 
TTCAAGAATT ACTACTCATT GGTGCTGGAC AGCCCTCTGG ACCGCGAGAG CGTGTCGGCC 
TATGAGCTGG TGGTGACTGC TCGGGACGGG GGCTCGCCTT CACTGTGGGC CACGGCCAGC 
GTGTCCGTGG AGGTGGCCGA CGTGAACGAC AATGCGCCGG CATTCTCGCA GTCCGAGTAC 
ACGGTGTTCG TGAAGGAGAA CAACCCGCCG GGCTGCCACA TCTTCACGGT GTCTGCGCGG 
GACGCGGACG CGCAGGAGAA CGCCCTGGTG TCCTACTCGC TGGTGGAACG GCGGGTGGGG 
GAGCGCGCGC TGTCGAGCTA CGTGTCGGTA CACGCGGAGA GCGGCAAGGT GTACGCGCTG 
CAGCCGCTGG ACCACGAGGA GCTAGAGCTG CTGCAGTTCC AGGTGAGTGC GCGCGATGCG 
GGCGTGCCGC CTCTGGGCAG CAACGTGACG CTGCAGGTGT TCGTGCTGGA CGAGAACGAC 
AACGCGCCGG CACTGCTGAT GCCTCGGGTG GGTGGCATCG GTGGCGCAGT GAGCGAGCTG 
GTGCCGCGGT CAGTGGGTGC GGGCCACGTG GTAGCGAAGG TGCGCGCAGT GGATGCAGAC 
TCAGGCTACA ACGCGTGGCT TTCGTATGAG CTGCAGCCTG GGACCGGCGG TGCGCGCATC 
CCGTTTCGCG TGGGGCTGTA CACGGGAGAG ATCAGCACGA CCCGTGCCCT GGACGAGGTG 
GACGCCCCGC GCCATCGCCT ACTGGTGCTG GTGAAGGACC ACGGTGAACC CTCATTGACC 
GCCACGGCCA CTGTGCTGGT GTCGCTGGTG GAGAGTGGCC AGGCACCCAA GGCCTCGTCC 
CAGGCGTCCG CTGGCGCCAC GGGCCCGGAA GCTGCACTGG TGGATGTCAA CGTGTACTTG 
ATCGTCGCCA TCTGCGCGGT GTCCAGTCTG TTGGTGCTCA CACTGCTGCT ATATACTGCT 
CTGCGGTGCT CCGCGCCGCC AACCGAAGGC GACTGTGGGC CGGGCAAGCC CACGCTGGTG 
TGCTCCAGCG CGGTGGGGAG CTGGTCATAC TCGCAGCAGA GGCAGCAGAG GGTGTGCTCT 
GGAGAGGGGT TGCCCAAGAC CGACCTCATG GCTTTTAGCC CTAGCCTTCC TCCTTGTCCA 
ATTAGCCGGG ATAGAGAGGA GAAACAGGAT GTGGACGTTG ATCTCTCAGC CAAAGTGAGT 
AATTTTTATT TATTCTTTCC AAAATGTCTT TGTTTTTCAT TCCTCAATGT TTCCACTCCT 
CTGGAAATAC ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PCDHA3 ( NM_018906.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_061729.1 Homo sapiens protocadherin alpha 3 (PCDHA3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu29341
Clone ID Related Accession (Same CDS sequence)	NM_018906.2 , NM_018906.3
Accession Version	NM_018906.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2853bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	protocadherin alpha-3 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF152311.1. This sequence is a reference standard in the RefSeqGene project. On May 22, 2001 this sequence version replaced NM_018906.1. Transcript Variant: This variant (1) includes the constant region exons and encodes the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: AF152311.1, SRR1803612.278083.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142680, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTGTTCT CCTGGCGAGA AGATCCTGGA GCCCAGTGCC TGCTGCTTTC TCTTCTGCTC 
CTCGCAGCCT CGGAGGTGGG GAGCGGCCAG CTCCACTACT CCGTCTCTGA GGAGGCCAAG 
CATGGCACCT TCGTGGGCCG CATCGCGCAG GACCTGGGGC TGGAGCTGGC GGAGCTGGTG 
CCGCGCCTGT TCCGGGTGGC GTCCAAAAGA CACGGGGACC TTCTGGAGGT AAATCTGCAG 
AATGGCATTT TGTTTGTGAA TTCTCGGATA GACCGCGAGG AACTGTGCGG GCGGAGCGCG 
GAGTGCAGCA TCCACCTGGA GGTGATCGTG GACAGGCCGC TGCAGGTTTT CCATGTGGAG 
GTGGAAGTGA AGGACATTAA TGACAACGCG CCAGTTTTTC CAATGGCTGT AAAGAATCTG 
TTTATTTCCG AATCCCGACA GCCTGGCTCT CGGTTTTCGC TAGAGGGCGC ATCAGATGCA 
GATATCGGAA CAAATTCGTT GTTGACTTAC AGTCTTGATT CCACTGAATA TTTTACCTTG 
GACGTTAAAA GAAATGATGA GGAAATTAAA TCCCTTGGAC TCGTGTTGAA AAAAAATTTA 
AATCGAGAGG ACACTCCTAA GCATTATTTA CTAATAACAG CAATTGATGG TGGGAAACCA 
GAGCTCACTG GCACGACTCA ACTAAAGATC ACTGTTTTAG ATGTAAACGA CAACGCCCCA 
GCGTTTGAGA GGACGATCTA TAAAGTCAGA TTACTCGAAA ATGCACCAAA TGGTACCCTA 
GTGGTGACCG TTAACGCCAC CGATTTGGAT GAAGGAGTAA ATAAGGATAT CGCGTATTCT 
TTCAATACGG ACATGTCAGC AGATATTCTG TCAAAATTCC ATTTAGATCC AGTCAATGGA 
CAAATCAGTG TAAAGGGTAA CATAGATTTC GAGGAAAGTA AGTCATATGA AATCCAGGTA 
GAAGCCACGG ATAAAGGAAA TCCCCCAATG TCAGATCACT GCACAGTTCT ACTCGAAATT 
GTGGACATCA ATGATAATGT ACCTGAGTTA GTTATTCAAT CACTATCTTT ACCTGTATTA 
GAAGACTCTC CACTTAGCAC AGTCATCGCT CTGATCAGCG TGTCCGACCG CGACTCAGGA 
GTCAATGGAC AGGTCACCTG CTCGCTGACG CCCCACGTCC CCTTCAAGCT GGTGTCCACC 
TTCAAGAATT ACTACTCATT GGTGCTGGAC AGCCCTCTGG ACCGCGAGAG CGTGTCGGCC 
TATGAGCTGG TGGTGACTGC TCGGGACGGG GGCTCGCCTT CACTGTGGGC CACGGCCAGC 
GTGTCCGTGG AGGTGGCCGA CGTGAACGAC AATGCGCCGG CATTCTCGCA GTCCGAGTAC 
ACGGTGTTCG TGAAGGAGAA CAACCCGCCG GGCTGCCACA TCTTCACGGT GTCTGCGCGG 
GACGCGGACG CGCAGGAGAA CGCCCTGGTG TCCTACTCGC TGGTGGAACG GCGGGTGGGG 
GAGCGCGCGC TGTCGAGCTA CGTGTCGGTA CACGCGGAGA GCGGCAAGGT GTACGCGCTG 
CAGCCGCTGG ACCACGAGGA GCTAGAGCTG CTGCAGTTCC AGGTGAGTGC GCGCGATGCG 
GGCGTGCCGC CTCTGGGCAG CAACGTGACG CTGCAGGTGT TCGTGCTGGA CGAGAACGAC 
AACGCGCCGG CACTGCTGAT GCCTCGGGTG GGTGGCATCG GTGGCGCAGT GAGCGAGCTG 
GTGCCGCGGT CAGTGGGTGC GGGCCACGTG GTAGCGAAGG TGCGCGCAGT GGATGCAGAC 
TCAGGCTACA ACGCGTGGCT TTCGTATGAG CTGCAGCCTG GGACCGGCGG TGCGCGCATC 
CCGTTTCGCG TGGGGCTGTA CACGGGAGAG ATCAGCACGA CCCGTGCCCT GGACGAGGTG 
GACGCCCCGC GCCATCGCCT ACTGGTGCTG GTGAAGGACC ACGGTGAACC CTCATTGACC 
GCCACGGCCA CTGTGCTGGT GTCGCTGGTG GAGAGTGGCC AGGCACCCAA GGCCTCGTCC 
CAGGCGTCCG CTGGCGCCAC GGGCCCGGAA GCTGCACTGG TGGATGTCAA CGTGTACTTG 
ATCGTCGCCA TCTGCGCGGT GTCCAGTCTG TTGGTGCTCA CACTGCTGCT ATATACTGCT 
CTGCGGTGCT CCGCGCCGCC AACCGAAGGC GACTGTGGGC CGGGCAAGCC CACGCTGGTG 
TGCTCCAGCG CGGTGGGGAG CTGGTCATAC TCGCAGCAGA GGCAGCAGAG GGTGTGCTCT 
GGAGAGGGGT TGCCCAAGAC CGACCTCATG GCTTTTAGCC CTAGCCTTCC TCCTTGTCCA 
ATTAGCCGGG ATAGAGAGGA GAAACAGGAT GTGGACGTTG ATCTCTCAGC CAAACCACGA 
CAGCCCAACC CTGACTGGCG TTACTCTGCC TCCCTGAGAG CAGGCATGCA CAGCTCTGTG 
CACCTAGAGG AGGCTGGCAT TCTACGGGCT GGTCCAGGAG GGCCTGATCA GCAGTGGCCA 
ACAGTATCCA GTGCAACACC AGAACCAGAG GCAGGAGAAG TGTCCCCTCC AGTCGGTGCG 
GGTGTCAACA GCAACAGCTG GACCTTTAAA TACGGACCAG GCAACCCCAA ACAATCCGGT 
CCCGGTGAGT TGCCCGACAA ATTCATTATC CCAGGATCTC CTGCAATCAT CTCCATCCGG 
CAGGAGCCTA CTAACAGCCA AATTGACAAA AGTGACTTCA TAACCTTCGG CAAAAAGGAG 
GAGACCAAGA AAAAGAAGAA AAAGAAGAAG GGTAACAAGA CCCAGGAGAA AAAAGAGAAA 
GGGAACAGCA CGACTGACAA CAGTGACCAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061729.1
CDS	1..2853
Translation	MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCPISRDREEKQDVDVDLSAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ

Target ORF information:

RefSeq Version	NM_018906.2
Organism	Homo sapiens(human)
Definition	Homo sapiens protocadherin alpha 3 (PCDHA3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018906.2

ORF Insert Sequence:

ATGTTGTTCT CCTGGCGAGA AGATCCTGGA GCCCAGTGCC TGCTGCTTTC TCTTCTGCTC 
CTCGCAGCCT CGGAGGTGGG GAGCGGCCAG CTCCACTACT CCGTCTCTGA GGAGGCCAAG 
CATGGCACCT TCGTGGGCCG CATCGCGCAG GACCTGGGGC TGGAGCTGGC GGAGCTGGTG 
CCGCGCCTGT TCCGGGTGGC GTCCAAAAGA CACGGGGACC TTCTGGAGGT AAATCTGCAG 
AATGGCATTT TGTTTGTGAA TTCTCGGATA GACCGCGAGG AACTGTGCGG GCGGAGCGCG 
GAGTGCAGCA TCCACCTGGA GGTGATCGTG GACAGGCCGC TGCAGGTTTT CCATGTGGAG 
GTGGAAGTGA AGGACATTAA TGACAACGCG CCAGTTTTTC CAATGGCTGT AAAGAATCTG 
TTTATTTCCG AATCCCGACA GCCTGGCTCT CGGTTTTCGC TAGAGGGCGC ATCAGATGCA 
GATATCGGAA CAAATTCGTT GTTGACTTAC AGTCTTGATT CCACTGAATA TTTTACCTTG 
GACGTTAAAA GAAATGATGA GGAAATTAAA TCCCTTGGAC TCGTGTTGAA AAAAAATTTA 
AATCGAGAGG ACACTCCTAA GCATTATTTA CTAATAACAG CAATTGATGG TGGGAAACCA 
GAGCTCACTG GCACGACTCA ACTAAAGATC ACTGTTTTAG ATGTAAACGA CAACGCCCCA 
GCGTTTGAGA GGACGATCTA TAAAGTCAGA TTACTCGAAA ATGCACCAAA TGGTACCCTA 
GTGGTGACCG TTAACGCCAC CGATTTGGAT GAAGGAGTAA ATAAGGATAT CGCGTATTCT 
TTCAATACGG ACATGTCAGC AGATATTCTG TCAAAATTCC ATTTAGATCC AGTCAATGGA 
CAAATCAGTG TAAAGGGTAA CATAGATTTC GAGGAAAGTA AGTCATATGA AATCCAGGTA 
GAAGCCACGG ATAAAGGAAA TCCCCCAATG TCAGATCACT GCACAGTTCT ACTCGAAATT 
GTGGACATCA ATGATAATGT ACCTGAGTTA GTTATTCAAT CACTATCTTT ACCTGTATTA 
GAAGACTCTC CACTTAGCAC AGTCATCGCT CTGATCAGCG TGTCCGACCG CGACTCAGGA 
GTCAATGGAC AGGTCACCTG CTCGCTGACG CCCCACGTCC CCTTCAAGCT GGTGTCCACC 
TTCAAGAATT ACTACTCATT GGTGCTGGAC AGCCCTCTGG ACCGCGAGAG CGTGTCGGCC 
TATGAGCTGG TGGTGACTGC TCGGGACGGG GGCTCGCCTT CACTGTGGGC CACGGCCAGC 
GTGTCCGTGG AGGTGGCCGA CGTGAACGAC AATGCGCCGG CATTCTCGCA GTCCGAGTAC 
ACGGTGTTCG TGAAGGAGAA CAACCCGCCG GGCTGCCACA TCTTCACGGT GTCTGCGCGG 
GACGCGGACG CGCAGGAGAA CGCCCTGGTG TCCTACTCGC TGGTGGAACG GCGGGTGGGG 
GAGCGCGCGC TGTCGAGCTA CGTGTCGGTA CACGCGGAGA GCGGCAAGGT GTACGCGCTG 
CAGCCGCTGG ACCACGAGGA GCTAGAGCTG CTGCAGTTCC AGGTGAGTGC GCGCGATGCG 
GGCGTGCCGC CTCTGGGCAG CAACGTGACG CTGCAGGTGT TCGTGCTGGA CGAGAACGAC 
AACGCGCCGG CACTGCTGAT GCCTCGGGTG GGTGGCATCG GTGGCGCAGT GAGCGAGCTG 
GTGCCGCGGT CAGTGGGTGC GGGCCACGTG GTAGCGAAGG TGCGCGCAGT GGATGCAGAC 
TCAGGCTACA ACGCGTGGCT TTCGTATGAG CTGCAGCCTG GGACCGGCGG TGCGCGCATC 
CCGTTTCGCG TGGGGCTGTA CACGGGAGAG ATCAGCACGA CCCGTGCCCT GGACGAGGTG 
GACGCCCCGC GCCATCGCCT ACTGGTGCTG GTGAAGGACC ACGGTGAACC CTCATTGACC 
GCCACGGCCA CTGTGCTGGT GTCGCTGGTG GAGAGTGGCC AGGCACCCAA GGCCTCGTCC 
CAGGCGTCCG CTGGCGCCAC GGGCCCGGAA GCTGCACTGG TGGATGTCAA CGTGTACTTG 
ATCGTCGCCA TCTGCGCGGT GTCCAGTCTG TTGGTGCTCA CACTGCTGCT ATATACTGCT 
CTGCGGTGCT CCGCGCCGCC AACCGAAGGC GACTGTGGGC CGGGCAAGCC CACGCTGGTG 
TGCTCCAGCG CGGTGGGGAG CTGGTCATAC TCGCAGCAGA GGCAGCAGAG GGTGTGCTCT 
GGAGAGGGGT TGCCCAAGAC CGACCTCATG GCTTTTAGCC CTAGCCTTCC TCCTTGTCCA 
ATTAGCCGGG ATAGAGAGGA GAAACAGGAT GTGGACGTTG ATCTCTCAGC CAAACCACGA 
CAGCCCAACC CTGACTGGCG TTACTCTGCC TCCCTGAGAG CAGGCATGCA CAGCTCTGTG 
CACCTAGAGG AGGCTGGCAT TCTACGGGCT GGTCCAGGAG GGCCTGATCA GCAGTGGCCA 
ACAGTATCCA GTGCAACACC AGAACCAGAG GCAGGAGAAG TGTCCCCTCC AGTCGGTGCG 
GGTGTCAACA GCAACAGCTG GACCTTTAAA TACGGACCAG GCAACCCCAA ACAATCCGGT 
CCCGGTGAGT TGCCCGACAA ATTCATTATC CCAGGATCTC CTGCAATCAT CTCCATCCGG 
CAGGAGCCTA CTAACAGCCA AATTGACAAA AGTGACTTCA TAACCTTCGG CAAAAAGGAG 
GAGACCAAGA AAAAGAAGAA AAAGAAGAAG GGTAACAAGA CCCAGGAGAA AAAAGAGAAA 
GGGAACAGCA CGACTGACAA CAGTGACCAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PCDHA3 ( NM_018906.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_061729.1 Homo sapiens protocadherin alpha 3 (PCDHA3), transcript variant 1, mRNA.

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CloneID	OHu29341
Clone ID Related Accession (Same CDS sequence)	NM_018906.2 , NM_018906.3
Accession Version	NM_018906.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2853bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	protocadherin alpha-3 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC005609.1, AF152311.1 and AC010223.6. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_018906.2. Transcript Variant: This variant (1) includes the constant region exons and encodes the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: AF152311.1, SRR1803612.278083.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142680, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000522353.3/ ENSP00000429808.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTTGTTCT CCTGGCGAGA AGATCCTGGA GCCCAGTGCC TGCTGCTTTC TCTTCTGCTC 
CTCGCAGCCT CGGAGGTGGG GAGCGGCCAG CTCCACTACT CCGTCTCTGA GGAGGCCAAG 
CATGGCACCT TCGTGGGCCG CATCGCGCAG GACCTGGGGC TGGAGCTGGC GGAGCTGGTG 
CCGCGCCTGT TCCGGGTGGC GTCCAAAAGA CACGGGGACC TTCTGGAGGT AAATCTGCAG 
AATGGCATTT TGTTTGTGAA TTCTCGGATA GACCGCGAGG AACTGTGCGG GCGGAGCGCG 
GAGTGCAGCA TCCACCTGGA GGTGATCGTG GACAGGCCGC TGCAGGTTTT CCATGTGGAG 
GTGGAAGTGA AGGACATTAA TGACAACGCG CCAGTTTTTC CAATGGCTGT AAAGAATCTG 
TTTATTTCCG AATCCCGACA GCCTGGCTCT CGGTTTTCGC TAGAGGGCGC ATCAGATGCA 
GATATCGGAA CAAATTCGTT GTTGACTTAC AGTCTTGATT CCACTGAATA TTTTACCTTG 
GACGTTAAAA GAAATGATGA GGAAATTAAA TCCCTTGGAC TCGTGTTGAA AAAAAATTTA 
AATCGAGAGG ACACTCCTAA GCATTATTTA CTAATAACAG CAATTGATGG TGGGAAACCA 
GAGCTCACTG GCACGACTCA ACTAAAGATC ACTGTTTTAG ATGTAAACGA CAACGCCCCA 
GCGTTTGAGA GGACGATCTA TAAAGTCAGA TTACTCGAAA ATGCACCAAA TGGTACCCTA 
GTGGTGACCG TTAACGCCAC CGATTTGGAT GAAGGAGTAA ATAAGGATAT CGCGTATTCT 
TTCAATACGG ACATGTCAGC AGATATTCTG TCAAAATTCC ATTTAGATCC AGTCAATGGA 
CAAATCAGTG TAAAGGGTAA CATAGATTTC GAGGAAAGTA AGTCATATGA AATCCAGGTA 
GAAGCCACGG ATAAAGGAAA TCCCCCAATG TCAGATCACT GCACAGTTCT ACTCGAAATT 
GTGGACATCA ATGATAATGT ACCTGAGTTA GTTATTCAAT CACTATCTTT ACCTGTATTA 
GAAGACTCTC CACTTAGCAC AGTCATCGCT CTGATCAGCG TGTCCGACCG CGACTCAGGA 
GTCAATGGAC AGGTCACCTG CTCGCTGACG CCCCACGTCC CCTTCAAGCT GGTGTCCACC 
TTCAAGAATT ACTACTCATT GGTGCTGGAC AGCCCTCTGG ACCGCGAGAG CGTGTCGGCC 
TATGAGCTGG TGGTGACTGC TCGGGACGGG GGCTCGCCTT CACTGTGGGC CACGGCCAGC 
GTGTCCGTGG AGGTGGCCGA CGTGAACGAC AATGCGCCGG CATTCTCGCA GTCCGAGTAC 
ACGGTGTTCG TGAAGGAGAA CAACCCGCCG GGCTGCCACA TCTTCACGGT GTCTGCGCGG 
GACGCGGACG CGCAGGAGAA CGCCCTGGTG TCCTACTCGC TGGTGGAACG GCGGGTGGGG 
GAGCGCGCGC TGTCGAGCTA CGTGTCGGTA CACGCGGAGA GCGGCAAGGT GTACGCGCTG 
CAGCCGCTGG ACCACGAGGA GCTAGAGCTG CTGCAGTTCC AGGTGAGTGC GCGCGATGCG 
GGCGTGCCGC CTCTGGGCAG CAACGTGACG CTGCAGGTGT TCGTGCTGGA CGAGAACGAC 
AACGCGCCGG CACTGCTGAT GCCTCGGGTG GGTGGCATCG GTGGCGCAGT GAGCGAGCTG 
GTGCCGCGGT CAGTGGGTGC GGGCCACGTG GTAGCGAAGG TGCGCGCAGT GGATGCAGAC 
TCAGGCTACA ACGCGTGGCT TTCGTATGAG CTGCAGCCTG GGACCGGCGG TGCGCGCATC 
CCGTTTCGCG TGGGGCTGTA CACGGGAGAG ATCAGCACGA CCCGTGCCCT GGACGAGGTG 
GACGCCCCGC GCCATCGCCT ACTGGTGCTG GTGAAGGACC ACGGTGAACC CTCATTGACC 
GCCACGGCCA CTGTGCTGGT GTCGCTGGTG GAGAGTGGCC AGGCACCCAA GGCCTCGTCC 
CAGGCGTCCG CTGGCGCCAC GGGCCCGGAA GCTGCACTGG TGGATGTCAA CGTGTACTTG 
ATCGTCGCCA TCTGCGCGGT GTCCAGTCTG TTGGTGCTCA CACTGCTGCT ATATACTGCT 
CTGCGGTGCT CCGCGCCGCC AACCGAAGGC GACTGTGGGC CGGGCAAGCC CACGCTGGTG 
TGCTCCAGCG CGGTGGGGAG CTGGTCATAC TCGCAGCAGA GGCAGCAGAG GGTGTGCTCT 
GGAGAGGGGT TGCCCAAGAC CGACCTCATG GCTTTTAGCC CTAGCCTTCC TCCTTGTCCA 
ATTAGCCGGG ATAGAGAGGA GAAACAGGAT GTGGACGTTG ATCTCTCAGC CAAACCACGA 
CAGCCCAACC CTGACTGGCG TTACTCTGCC TCCCTGAGAG CAGGCATGCA CAGCTCTGTG 
CACCTAGAGG AGGCTGGCAT TCTACGGGCT GGTCCAGGAG GGCCTGATCA GCAGTGGCCA 
ACAGTATCCA GTGCAACACC AGAACCAGAG GCAGGAGAAG TGTCCCCTCC AGTCGGTGCG 
GGTGTCAACA GCAACAGCTG GACCTTTAAA TACGGACCAG GCAACCCCAA ACAATCCGGT 
CCCGGTGAGT TGCCCGACAA ATTCATTATC CCAGGATCTC CTGCAATCAT CTCCATCCGG 
CAGGAGCCTA CTAACAGCCA AATTGACAAA AGTGACTTCA TAACCTTCGG CAAAAAGGAG 
GAGACCAAGA AAAAGAAGAA AAAGAAGAAG GGTAACAAGA CCCAGGAGAA AAAAGAGAAA 
GGGAACAGCA CGACTGACAA CAGTGACCAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061729.1
CDS	142..2994
Translation	MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCPISRDREEKQDVDVDLSAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ

Target ORF information:

RefSeq Version	NM_018906.3
Organism	Homo sapiens(human)
Definition	Homo sapiens protocadherin alpha 3 (PCDHA3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018906.3

ORF Insert Sequence:

ATGTTGTTCT CCTGGCGAGA AGATCCTGGA GCCCAGTGCC TGCTGCTTTC TCTTCTGCTC 
CTCGCAGCCT CGGAGGTGGG GAGCGGCCAG CTCCACTACT CCGTCTCTGA GGAGGCCAAG 
CATGGCACCT TCGTGGGCCG CATCGCGCAG GACCTGGGGC TGGAGCTGGC GGAGCTGGTG 
CCGCGCCTGT TCCGGGTGGC GTCCAAAAGA CACGGGGACC TTCTGGAGGT AAATCTGCAG 
AATGGCATTT TGTTTGTGAA TTCTCGGATA GACCGCGAGG AACTGTGCGG GCGGAGCGCG 
GAGTGCAGCA TCCACCTGGA GGTGATCGTG GACAGGCCGC TGCAGGTTTT CCATGTGGAG 
GTGGAAGTGA AGGACATTAA TGACAACGCG CCAGTTTTTC CAATGGCTGT AAAGAATCTG 
TTTATTTCCG AATCCCGACA GCCTGGCTCT CGGTTTTCGC TAGAGGGCGC ATCAGATGCA 
GATATCGGAA CAAATTCGTT GTTGACTTAC AGTCTTGATT CCACTGAATA TTTTACCTTG 
GACGTTAAAA GAAATGATGA GGAAATTAAA TCCCTTGGAC TCGTGTTGAA AAAAAATTTA 
AATCGAGAGG ACACTCCTAA GCATTATTTA CTAATAACAG CAATTGATGG TGGGAAACCA 
GAGCTCACTG GCACGACTCA ACTAAAGATC ACTGTTTTAG ATGTAAACGA CAACGCCCCA 
GCGTTTGAGA GGACGATCTA TAAAGTCAGA TTACTCGAAA ATGCACCAAA TGGTACCCTA 
GTGGTGACCG TTAACGCCAC CGATTTGGAT GAAGGAGTAA ATAAGGATAT CGCGTATTCT 
TTCAATACGG ACATGTCAGC AGATATTCTG TCAAAATTCC ATTTAGATCC AGTCAATGGA 
CAAATCAGTG TAAAGGGTAA CATAGATTTC GAGGAAAGTA AGTCATATGA AATCCAGGTA 
GAAGCCACGG ATAAAGGAAA TCCCCCAATG TCAGATCACT GCACAGTTCT ACTCGAAATT 
GTGGACATCA ATGATAATGT ACCTGAGTTA GTTATTCAAT CACTATCTTT ACCTGTATTA 
GAAGACTCTC CACTTAGCAC AGTCATCGCT CTGATCAGCG TGTCCGACCG CGACTCAGGA 
GTCAATGGAC AGGTCACCTG CTCGCTGACG CCCCACGTCC CCTTCAAGCT GGTGTCCACC 
TTCAAGAATT ACTACTCATT GGTGCTGGAC AGCCCTCTGG ACCGCGAGAG CGTGTCGGCC 
TATGAGCTGG TGGTGACTGC TCGGGACGGG GGCTCGCCTT CACTGTGGGC CACGGCCAGC 
GTGTCCGTGG AGGTGGCCGA CGTGAACGAC AATGCGCCGG CATTCTCGCA GTCCGAGTAC 
ACGGTGTTCG TGAAGGAGAA CAACCCGCCG GGCTGCCACA TCTTCACGGT GTCTGCGCGG 
GACGCGGACG CGCAGGAGAA CGCCCTGGTG TCCTACTCGC TGGTGGAACG GCGGGTGGGG 
GAGCGCGCGC TGTCGAGCTA CGTGTCGGTA CACGCGGAGA GCGGCAAGGT GTACGCGCTG 
CAGCCGCTGG ACCACGAGGA GCTAGAGCTG CTGCAGTTCC AGGTGAGTGC GCGCGATGCG 
GGCGTGCCGC CTCTGGGCAG CAACGTGACG CTGCAGGTGT TCGTGCTGGA CGAGAACGAC 
AACGCGCCGG CACTGCTGAT GCCTCGGGTG GGTGGCATCG GTGGCGCAGT GAGCGAGCTG 
GTGCCGCGGT CAGTGGGTGC GGGCCACGTG GTAGCGAAGG TGCGCGCAGT GGATGCAGAC 
TCAGGCTACA ACGCGTGGCT TTCGTATGAG CTGCAGCCTG GGACCGGCGG TGCGCGCATC 
CCGTTTCGCG TGGGGCTGTA CACGGGAGAG ATCAGCACGA CCCGTGCCCT GGACGAGGTG 
GACGCCCCGC GCCATCGCCT ACTGGTGCTG GTGAAGGACC ACGGTGAACC CTCATTGACC 
GCCACGGCCA CTGTGCTGGT GTCGCTGGTG GAGAGTGGCC AGGCACCCAA GGCCTCGTCC 
CAGGCGTCCG CTGGCGCCAC GGGCCCGGAA GCTGCACTGG TGGATGTCAA CGTGTACTTG 
ATCGTCGCCA TCTGCGCGGT GTCCAGTCTG TTGGTGCTCA CACTGCTGCT ATATACTGCT 
CTGCGGTGCT CCGCGCCGCC AACCGAAGGC GACTGTGGGC CGGGCAAGCC CACGCTGGTG 
TGCTCCAGCG CGGTGGGGAG CTGGTCATAC TCGCAGCAGA GGCAGCAGAG GGTGTGCTCT 
GGAGAGGGGT TGCCCAAGAC CGACCTCATG GCTTTTAGCC CTAGCCTTCC TCCTTGTCCA 
ATTAGCCGGG ATAGAGAGGA GAAACAGGAT GTGGACGTTG ATCTCTCAGC CAAACCACGA 
CAGCCCAACC CTGACTGGCG TTACTCTGCC TCCCTGAGAG CAGGCATGCA CAGCTCTGTG 
CACCTAGAGG AGGCTGGCAT TCTACGGGCT GGTCCAGGAG GGCCTGATCA GCAGTGGCCA 
ACAGTATCCA GTGCAACACC AGAACCAGAG GCAGGAGAAG TGTCCCCTCC AGTCGGTGCG 
GGTGTCAACA GCAACAGCTG GACCTTTAAA TACGGACCAG GCAACCCCAA ACAATCCGGT 
CCCGGTGAGT TGCCCGACAA ATTCATTATC CCAGGATCTC CTGCAATCAT CTCCATCCGG 
CAGGAGCCTA CTAACAGCCA AATTGACAAA AGTGACTTCA TAACCTTCGG CAAAAAGGAG 
GAGACCAAGA AAAAGAAGAA AAAGAAGAAG GGTAACAAGA CCCAGGAGAA AAAAGAGAAA 
GGGAACAGCA CGACTGACAA CAGTGACCAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Exome sequencing in a family with restless legs syndrome.
Movement disorders : official journal of the Movement Disorder Society27(13)1686-9(2012 Nov)
Weissbach A,Siegesmund K,Br?ggemann N,Schmidt A,Kasten M,Pichler I,Muhle H,Lohmann E,Lohnau T,Schwinger E,Hagenah J,Stephani U,Pramstaller PP,Klein C,Lohmann K

Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.
PLoS genetics8(5)e1002695(2012)
Fox CS,Liu Y,White CC,Feitosa M,Smith AV,Heard-Costa N,Lohman K,,,,Johnson AD,Foster MC,Greenawalt DM,Griffin P,Ding J,Newman AB,Tylavsky F,Miljkovic I,Kritchevsky SB,Launer L,Garcia M,Eiriksdottir G,Carr JJ,Gudnason V,Harris TB,Cupples LA,Borecki IB

Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence.
Psychiatry research165(1-2)1-9(2009 Jan)
Greg?rio SP,Sallet PC,Do KA,Lin E,Gattaz WF,Dias-Neto E

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.
Proteomics7(11)1775-85(2007 Jun)
Wu C,Ma MH,Brown KR,Geisler M,Li L,Tzeng E,Jia CY,Jurisica I,Li SS

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.
Genome research11(3)389-404(2001 Mar)
Wu Q,Zhang T,Cheng JF,Kim Y,Grimwood J,Schmutz J,Dickson M,Noonan JP,Zhang MQ,Myers RM,Maniatis T

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PCDHA3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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