CTLA4 cDNA ORF clone, Macaca mulatta(Rhesus monkey)

Gene
Clones
gRNAs

Summary

Gene Symbol	CTLA4
Entrez Gene ID	705673
Full Name	cytotoxic T-lymphocyte associated protein 4
Synonyms	CTLA-4
Gene Type	protein-coding
Organism	Macaca mulatta(Rhesus monkey)

mRNA and Protein(s)

mRNA	Protein	Name
XM_015110723.1	XP_014966209.1	cytotoxic T-lymphocyte protein 4 isoform X2
NM_001044739.1	NP_001038204.1	cytotoxic T-lymphocyte protein 4 precursor
XM_015110723.2	XP_014966209.1	cytotoxic T-lymphocyte protein 4 isoform X2
XM_015110722.2	XP_014966208.1	cytotoxic T-lymphocyte protein 4 isoform X1
XM_015110722.1	XP_014966208.1	cytotoxic T-lymphocyte protein 4 isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Ctla4	NP_113862.1
Pan troglodytes (chimpanzee)	CTLA4	XP_526000.1
Mus musculus (house mouse)	Ctla4	NP_033973.2
Xenopus tropicalis (tropical clawed frog)	ctla4	XP_002936576.1
Bos taurus (cattle)	CTLA4	NP_776722.1
Homo sapiens (human)	CTLA4	NP_005205.2
	CTLA4	NP_001038204.1
Canis lupus familiaris (dog)	CTLA4	NP_001003106.1
Gallus gallus (chicken)	CTLA4	NP_001035180.1

Gene Ontology
Bibliography

Related articles in PubMed

CTLA-4
McGary CS, Deleage C, Harper J, Micci L, Ribeiro SP, Paganini S, Kuri-Cervantes L, Benne C, Ryan ES, Balderas R, Jean S, Easley K, Marconi V, Silvestri G, Estes JD, Sekaly RP, Paiardini M
Immunity47(4)776-788.e5(2017 Oct)

Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques.
Yan G, Zhang G, Fang X, Zhang Y, Li C, Ling F, Cooper DN, Li Q, Li Y, van Gool AJ, Du H, Chen J, Chen R, Zhang P, Huang Z, Thompson JR, Meng Y, Bai Y, Wang J, Zhuo M, Wang T, Huang Y, Wei L, Li J, Wang Z, Hu H, Yang P, Le L, Stenson PD, Li B, Liu X, Ball EV, An N, Huang Q, Zhang Y, Fan W, Zhang X, Li Y, Wang W, Katze MG, Su B, Nielsen R, Yang H, Wang J, Wang X, Wang J
Nature biotechnology29(11)1019-23(2011 Oct)

Cloning, sequencing, and homology analysis of nonhuman primate Fas/Fas-ligand and co-stimulatory molecules.
Villinger F, Bostik P, Mayne A, King CL, Genain CP, Weiss WR, Ansari AA
Immunogenetics53(4)315-28(2001 May-Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that CTLA-4(+)PD-1(-) memory CD4(+) T cells, which share phenotypic markers with regulatory T cells, were enriched in SIV DNA in blood, lymph nodes (LN), spleen, and gut, and contained replication-competent and infectious virus.
Title: CTLA-4

The following CTLA4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CTLA4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMb01744	NM_001044739.1 Latest version!	Macaca mulatta cytotoxic T-lymphocyte associated protein 4 (CTLA4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OMb44404	XM_015110722.2 Latest version!	Macaca mulatta cytotoxic T-lymphocyte associated protein 4 (CTLA4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$104.30 $149.00
OMb44405	XM_015110723.2 Latest version!	Macaca mulatta cytotoxic T-lymphocyte associated protein 4 (CTLA4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$104.30 $149.00
View Old Accession Versions >>
OMb44405	XM_015110723.1	Macaca mulatta cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$104.30 $149.00
OMb44404	XM_015110722.1	Macaca mulatta cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$104.30 $149.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CTLA4 ( NM_001044739.1 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> NP_001038204.1 Macaca mulatta cytotoxic T-lymphocyte associated protein 4 (CTLA4), mRNA.

Price & Availability↑

CloneID	OMb01744
Clone ID Related Accession (Same CDS sequence)	NM_001044739.1
Accession Version	NM_001044739.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 672bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-27
Organism	Macaca mulatta(Rhesus monkey)
Product	cytotoxic T-lymphocyte protein 4 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF344846.1. On or before Aug 31, 2006 this sequence version replaced XM_001104423.1, XM_001104342.1, XM_001104180.1. ##Evidence-Data-START## Transcript exon combination :: AF344846.1, CO647230.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4688380, SAMEA4688428 [ECO:0000348] ##Evidence-Data-END##

ATGGCTTGCC TTGGATTTCA GCGGCACAAG GCTCGGCTCA ACCTGGCTAC CAGGACCCGG 
CCCTACACTC TCCTGTTTTC TCTTCTCTTC ATCCCTGTCT TCTCCAAAGC AATGCACGTG 
GCCCAGCCTG CTGTGGTGCT GGCCAACAGC CGAGGGATCG CCAGCTTTGT GTGTGAGTAT 
GCATCTCCAG GCAAAGCCAC TGAGGTCCGG GTGACAGTGC TTCGGCAGGC CGACAGCCAG 
GTGACTGAAG TCTGTGCGGC AACATACATG ATGGGGAATG AGTTGACCTT CCTAGATGAT 
TCCATCTGCA CGGGCACCTC CAGTGGAAAT CAAGTGAACC TCACTATCCA AGGACTGAGG 
GCTATGGACA CAGGACTCTA CATCTGCAAG GTGGAGCTCA TGTACCCACC ACCATACTAC 
ATGGGCATAG GCAATGGAAC CCAGATTTAT GTAATTGATC CAGAACCGTG CCCAGATTCT 
GACTTCCTCC TCTGGATCCT TGCAGCAGTT AGTTCGGGGT TGTTTTTTTA TAGCTTTCTC 
CTCACAGCTG TTTCTTTGAG CAAAATGCTA AAGAAAAGAA GCCCTCTCAC AACAGGGGTC 
TATGTGAAAA TGCCCCCAAC AGAGCCAGAA TGTGAAAAGC AATTTCAGCC TTATTTTATT 
CCCATCAATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001038204.1
CDS	101..772
Translation	MACLGFQRHKARLNLATRTRPYTLLFSLLFIPVFSKAMHVAQPAVVLANSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYMGIGNGTQIYVIDPEPCPDSDFLLWILAAVSSGLFFYSFLLTAVSLSKMLKKRSPLTTGVYVKMPPTEPECEKQFQPYFIPIN

Target ORF information:

RefSeq Version	NM_001044739.1
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta cytotoxic T-lymphocyte associated protein 4 (CTLA4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001044739.1

ORF Insert Sequence:

ATGGCTTGCC TTGGATTTCA GCGGCACAAG GCTCGGCTCA ACCTGGCTAC CAGGACCCGG 
CCCTACACTC TCCTGTTTTC TCTTCTCTTC ATCCCTGTCT TCTCCAAAGC AATGCACGTG 
GCCCAGCCTG CTGTGGTGCT GGCCAACAGC CGAGGGATCG CCAGCTTTGT GTGTGAGTAT 
GCATCTCCAG GCAAAGCCAC TGAGGTCCGG GTGACAGTGC TTCGGCAGGC CGACAGCCAG 
GTGACTGAAG TCTGTGCGGC AACATACATG ATGGGGAATG AGTTGACCTT CCTAGATGAT 
TCCATCTGCA CGGGCACCTC CAGTGGAAAT CAAGTGAACC TCACTATCCA AGGACTGAGG 
GCTATGGACA CAGGACTCTA CATCTGCAAG GTGGAGCTCA TGTACCCACC ACCATACTAC 
ATGGGCATAG GCAATGGAAC CCAGATTTAT GTAATTGATC CAGAACCGTG CCCAGATTCT 
GACTTCCTCC TCTGGATCCT TGCAGCAGTT AGTTCGGGGT TGTTTTTTTA TAGCTTTCTC 
CTCACAGCTG TTTCTTTGAG CAAAATGCTA AAGAAAAGAA GCCCTCTCAC AACAGGGGTC 
TATGTGAAAA TGCCCCCAAC AGAGCCAGAA TGTGAAAAGC AATTTCAGCC TTATTTTATT 
CCCATCAATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CTLA4 ( XM_015110722.2 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> XP_014966208.1 Macaca mulatta cytotoxic T-lymphocyte associated protein 4 (CTLA4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMb44404
Clone ID Related Accession (Same CDS sequence)	XM_015110722.2 , XM_015110722.1
Accession Version	XM_015110722.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 561bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-25
Organism	Macaca mulatta(Rhesus monkey)
Product	cytotoxic T-lymphocyte protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041765.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 23, 2019 this sequence version replaced XM_015110722.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCACGTGG CCCAGCCTGC TGTGGTGCTG GCCAACAGCC GAGGGATCGC CAGCTTTGTG 
TGTGAGTATG CATCTCCAGG CAAAGCCACT GAGGTCCGGG TGACAGTGCT TCGGCAGGCC 
GACAGCCAGG TGACTGAAGT CTGTGCGGCA ACATACATGA TGGGGAATGA GTTGACCTTC 
CTAGATGATT CCATCTGCAC GGGCACCTCC AGTGGAAATC AAGTGAACCT CACTATCCAA 
GGACTGAGGG CTATGGACAC AGGACTCTAC ATCTGCAAGG TGGAGCTCAT GTACCCACCA 
CCATACTACA TGGGCATAGG CAATGGAACC CAGATTTATG TAATTGATCC AGAACCGTGC 
CCAGATTCTG ACTTCCTCCT CTGGATCCTT GCAGCAGTTA GTTCGGGGTT GTTTTTTTAT 
AGCTTTCTCC TCACAGCTGT TTCTTTGAGC AAAATGCTAA AGAAAAGAAG CCCTCTCACA 
ACAGGGGTCT ATGTGAAAAT GCCCCCAACA GAGCCAGAAT GTGAAAAGCA ATTTCAGCCT 
TATTTTATTC CCATCAATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_014966208.1
CDS	1341..1901
Translation	MHVAQPAVVLANSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYMGIGNGTQIYVIDPEPCPDSDFLLWILAAVSSGLFFYSFLLTAVSLSKMLKKRSPLTTGVYVKMPPTEPECEKQFQPYFIPIN

Target ORF information:

RefSeq Version	XM_015110722.2
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta cytotoxic T-lymphocyte associated protein 4 (CTLA4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015110722.2

ORF Insert Sequence:

ATGCACGTGG CCCAGCCTGC TGTGGTGCTG GCCAACAGCC GAGGGATCGC CAGCTTTGTG 
TGTGAGTATG CATCTCCAGG CAAAGCCACT GAGGTCCGGG TGACAGTGCT TCGGCAGGCC 
GACAGCCAGG TGACTGAAGT CTGTGCGGCA ACATACATGA TGGGGAATGA GTTGACCTTC 
CTAGATGATT CCATCTGCAC GGGCACCTCC AGTGGAAATC AAGTGAACCT CACTATCCAA 
GGACTGAGGG CTATGGACAC AGGACTCTAC ATCTGCAAGG TGGAGCTCAT GTACCCACCA 
CCATACTACA TGGGCATAGG CAATGGAACC CAGATTTATG TAATTGATCC AGAACCGTGC 
CCAGATTCTG ACTTCCTCCT CTGGATCCTT GCAGCAGTTA GTTCGGGGTT GTTTTTTTAT 
AGCTTTCTCC TCACAGCTGT TTCTTTGAGC AAAATGCTAA AGAAAAGAAG CCCTCTCACA 
ACAGGGGTCT ATGTGAAAAT GCCCCCAACA GAGCCAGAAT GTGAAAAGCA ATTTCAGCCT 
TATTTTATTC CCATCAATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CTLA4 ( XM_015110722.1 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> XP_014966208.1 Macaca mulatta cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMb44404
Clone ID Related Accession (Same CDS sequence)	XM_015110722.2 , XM_015110722.1
Accession Version	XM_015110722.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 561bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-12-20
Organism	Macaca mulatta(Rhesus monkey)
Product	cytotoxic T-lymphocyte protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014805361.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Macaca mulatta Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCACGTGG CCCAGCCTGC TGTGGTGCTG GCCAACAGCC GAGGGATCGC CAGCTTTGTG 
TGTGAGTATG CATCTCCAGG CAAAGCCACT GAGGTCCGGG TGACAGTGCT TCGGCAGGCC 
GACAGCCAGG TGACTGAAGT CTGTGCGGCA ACATACATGA TGGGGAATGA GTTGACCTTC 
CTAGATGATT CCATCTGCAC GGGCACCTCC AGTGGAAATC AAGTGAACCT CACTATCCAA 
GGACTGAGGG CTATGGACAC AGGACTCTAC ATCTGCAAGG TGGAGCTCAT GTACCCACCA 
CCATACTACA TGGGCATAGG CAATGGAACC CAGATTTATG TAATTGATCC AGAACCGTGC 
CCAGATTCTG ACTTCCTCCT CTGGATCCTT GCAGCAGTTA GTTCGGGGTT GTTTTTTTAT 
AGCTTTCTCC TCACAGCTGT TTCTTTGAGC AAAATGCTAA AGAAAAGAAG CCCTCTCACA 
ACAGGGGTCT ATGTGAAAAT GCCCCCAACA GAGCCAGAAT GTGAAAAGCA ATTTCAGCCT 
TATTTTATTC CCATCAATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_014966208.1
CDS	317..877
Translation	MHVAQPAVVLANSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYMGIGNGTQIYVIDPEPCPDSDFLLWILAAVSSGLFFYSFLLTAVSLSKMLKKRSPLTTGVYVKMPPTEPECEKQFQPYFIPIN

Target ORF information:

RefSeq Version	XM_015110722.1
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015110722.1

ORF Insert Sequence:

ATGCACGTGG CCCAGCCTGC TGTGGTGCTG GCCAACAGCC GAGGGATCGC CAGCTTTGTG 
TGTGAGTATG CATCTCCAGG CAAAGCCACT GAGGTCCGGG TGACAGTGCT TCGGCAGGCC 
GACAGCCAGG TGACTGAAGT CTGTGCGGCA ACATACATGA TGGGGAATGA GTTGACCTTC 
CTAGATGATT CCATCTGCAC GGGCACCTCC AGTGGAAATC AAGTGAACCT CACTATCCAA 
GGACTGAGGG CTATGGACAC AGGACTCTAC ATCTGCAAGG TGGAGCTCAT GTACCCACCA 
CCATACTACA TGGGCATAGG CAATGGAACC CAGATTTATG TAATTGATCC AGAACCGTGC 
CCAGATTCTG ACTTCCTCCT CTGGATCCTT GCAGCAGTTA GTTCGGGGTT GTTTTTTTAT 
AGCTTTCTCC TCACAGCTGT TTCTTTGAGC AAAATGCTAA AGAAAAGAAG CCCTCTCACA 
ACAGGGGTCT ATGTGAAAAT GCCCCCAACA GAGCCAGAAT GTGAAAAGCA ATTTCAGCCT 
TATTTTATTC CCATCAATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CTLA4 ( XM_015110723.1 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> XP_014966209.1 Macaca mulatta cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMb44405
Clone ID Related Accession (Same CDS sequence)	XM_015110723.1 , XM_015110723.2
Accession Version	XM_015110723.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 525bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-12-20
Organism	Macaca mulatta(Rhesus monkey)
Product	cytotoxic T-lymphocyte protein 4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014805361.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Macaca mulatta Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTGCC TTGGATTTCA GCGGCACAAG GCTCGGCTCA ACCTGGCTAC CAGGACCCGG 
CCCTACACTC TCCTGTTTTC TCTTCTCTTC ATCCCTGTCT TCTCCAAAGC AATGCACGTG 
GCCCAGCCTG CTGTGGTGCT GGCCAACAGC CGAGGGATCG CCAGCTTTGT GTGTGAGTAT 
GCATCTCCAG GCAAAGCCAC TGAGGTCCGG GTGACAGTGC TTCGGCAGGC CGACAGCCAG 
GTGACTGAAG TCTGTGCGGC AACATACATG ATGGGGAATG AGTTGACCTT CCTAGATGAT 
TCCATCTGCA CGGGCACCTC CAGTGGAAAT CAAGTGAACC TCACTATCCA AGGACTGAGG 
GCTATGGACA CAGGACTCTA CATCTGCAAG GTGGAGCTCA TGTACCCACC ACCATACTAC 
ATGGGCATAG GCAATGGAAC CCAGATTTAT GTAATTGCTA AAGAAAAGAA GCCCTCTCAC 
AACAGGGGTC TATGTGAAAA TGCCCCCAAC AGAGCCAGAA TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_014966209.1
CDS	176..700
Translation	MACLGFQRHKARLNLATRTRPYTLLFSLLFIPVFSKAMHVAQPAVVLANSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYMGIGNGTQIYVIAKEKKPSHNRGLCENAPNRARM

Target ORF information:

RefSeq Version	XM_015110723.1
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015110723.1

ORF Insert Sequence:

ATGGCTTGCC TTGGATTTCA GCGGCACAAG GCTCGGCTCA ACCTGGCTAC CAGGACCCGG 
CCCTACACTC TCCTGTTTTC TCTTCTCTTC ATCCCTGTCT TCTCCAAAGC AATGCACGTG 
GCCCAGCCTG CTGTGGTGCT GGCCAACAGC CGAGGGATCG CCAGCTTTGT GTGTGAGTAT 
GCATCTCCAG GCAAAGCCAC TGAGGTCCGG GTGACAGTGC TTCGGCAGGC CGACAGCCAG 
GTGACTGAAG TCTGTGCGGC AACATACATG ATGGGGAATG AGTTGACCTT CCTAGATGAT 
TCCATCTGCA CGGGCACCTC CAGTGGAAAT CAAGTGAACC TCACTATCCA AGGACTGAGG 
GCTATGGACA CAGGACTCTA CATCTGCAAG GTGGAGCTCA TGTACCCACC ACCATACTAC 
ATGGGCATAG GCAATGGAAC CCAGATTTAT GTAATTGCTA AAGAAAAGAA GCCCTCTCAC 
AACAGGGGTC TATGTGAAAA TGCCCCCAAC AGAGCCAGAA TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CTLA4 ( XM_015110723.2 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> XP_014966209.1 Macaca mulatta cytotoxic T-lymphocyte associated protein 4 (CTLA4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMb44405
Clone ID Related Accession (Same CDS sequence)	XM_015110723.1 , XM_015110723.2
Accession Version	XM_015110723.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 525bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-25
Organism	Macaca mulatta(Rhesus monkey)
Product	cytotoxic T-lymphocyte protein 4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041765.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 23, 2019 this sequence version replaced XM_015110723.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTGCC TTGGATTTCA GCGGCACAAG GCTCGGCTCA ACCTGGCTAC CAGGACCCGG 
CCCTACACTC TCCTGTTTTC TCTTCTCTTC ATCCCTGTCT TCTCCAAAGC AATGCACGTG 
GCCCAGCCTG CTGTGGTGCT GGCCAACAGC CGAGGGATCG CCAGCTTTGT GTGTGAGTAT 
GCATCTCCAG GCAAAGCCAC TGAGGTCCGG GTGACAGTGC TTCGGCAGGC CGACAGCCAG 
GTGACTGAAG TCTGTGCGGC AACATACATG ATGGGGAATG AGTTGACCTT CCTAGATGAT 
TCCATCTGCA CGGGCACCTC CAGTGGAAAT CAAGTGAACC TCACTATCCA AGGACTGAGG 
GCTATGGACA CAGGACTCTA CATCTGCAAG GTGGAGCTCA TGTACCCACC ACCATACTAC 
ATGGGCATAG GCAATGGAAC CCAGATTTAT GTAATTGCTA AAGAAAAGAA GCCCTCTCAC 
AACAGGGGTC TATGTGAAAA TGCCCCCAAC AGAGCCAGAA TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_014966209.1
CDS	456..980
Translation	MACLGFQRHKARLNLATRTRPYTLLFSLLFIPVFSKAMHVAQPAVVLANSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYMGIGNGTQIYVIAKEKKPSHNRGLCENAPNRARM

Target ORF information:

RefSeq Version	XM_015110723.2
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta cytotoxic T-lymphocyte associated protein 4 (CTLA4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015110723.2

ORF Insert Sequence:

ATGGCTTGCC TTGGATTTCA GCGGCACAAG GCTCGGCTCA ACCTGGCTAC CAGGACCCGG 
CCCTACACTC TCCTGTTTTC TCTTCTCTTC ATCCCTGTCT TCTCCAAAGC AATGCACGTG 
GCCCAGCCTG CTGTGGTGCT GGCCAACAGC CGAGGGATCG CCAGCTTTGT GTGTGAGTAT 
GCATCTCCAG GCAAAGCCAC TGAGGTCCGG GTGACAGTGC TTCGGCAGGC CGACAGCCAG 
GTGACTGAAG TCTGTGCGGC AACATACATG ATGGGGAATG AGTTGACCTT CCTAGATGAT 
TCCATCTGCA CGGGCACCTC CAGTGGAAAT CAAGTGAACC TCACTATCCA AGGACTGAGG 
GCTATGGACA CAGGACTCTA CATCTGCAAG GTGGAGCTCA TGTACCCACC ACCATACTAC 
ATGGGCATAG GCAATGGAAC CCAGATTTAT GTAATTGCTA AAGAAAAGAA GCCCTCTCAC 
AACAGGGGTC TATGTGAAAA TGCCCCCAAC AGAGCCAGAA TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

CTLA-4
Immunity47(4)776-788.e5(2017 Oct)
McGary CS,Deleage C,Harper J,Micci L,Ribeiro SP,Paganini S,Kuri-Cervantes L,Benne C,Ryan ES,Balderas R,Jean S,Easley K,Marconi V,Silvestri G,Estes JD,Sekaly RP,Paiardini M

Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques.
Nature biotechnology29(11)1019-23(2011 Oct)
Yan G,Zhang G,Fang X,Zhang Y,Li C,Ling F,Cooper DN,Li Q,Li Y,van Gool AJ,Du H,Chen J,Chen R,Zhang P,Huang Z,Thompson JR,Meng Y,Bai Y,Wang J,Zhuo M,Wang T,Huang Y,Wei L,Li J,Wang Z,Hu H,Yang P,Le L,Stenson PD,Li B,Liu X,Ball EV,An N,Huang Q,Zhang Y,Fan W,Zhang X,Li Y,Wang W,Katze MG,Su B,Nielsen R,Yang H,Wang J,Wang X,Wang J

Cloning, sequencing, and homology analysis of nonhuman primate Fas/Fas-ligand and co-stimulatory molecules.
Immunogenetics53(4)315-28(2001 May-Jun)
Villinger F,Bostik P,Mayne A,King CL,Genain CP,Weiss WR,Ansari AA

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CTLA4 cDNA ORF clone, Macaca mulatta(Rhesus monkey)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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