Uvrag cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Uvrag
Entrez Gene ID	78610
Full Name	UV radiation resistance associated gene
Synonyms	9530039D02Rik,AI648770,BB124205,Uvrag1,Uvragl
General protein information	Preferred Names UV radiation resistance associated gene Names UV radiation resistance associated protein UV radiation resistance-associated gene protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 E1

mRNA and Protein(s)

mRNA	Protein	Name
XM_006508349.2	XP_006508412.1	UV radiation resistance associated protein isoform X1
XM_030243116.1	XP_030098976.1	UV radiation resistance-associated protein isoform X2
XM_006508349.3	XP_006508412.1	UV radiation resistance-associated protein isoform X1
NM_178635.3	NP_848750.3	UV radiation resistance-associated protein

Pathways from BioSystems

Homologies

	UVRAG	XP_001086725.1
Canis lupus familiaris (dog)	UVRAG	XP_849891.1
Mus musculus (house mouse)	Uvrag	NP_848750.3
Danio rerio (zebrafish)	uvrag	NP_957363.1
Xenopus tropicalis (tropical clawed frog)	uvrag	XP_002941209.2
Bos taurus (cattle)	UVRAG	NP_001179955.1
Rattus norvegicus (Norway rat)	Uvrag	NP_001101006.1
Homo sapiens (human)	UVRAG	NP_003360.2
Pan troglodytes (chimpanzee)	UVRAG	XP_508649.3
Gallus gallus (chicken)	UVRAG	NP_001026010.1

Gene Ontology
Bibliography

Related articles in PubMed

UVRAG Deficiency Exacerbates Doxorubicin-Induced Cardiotoxicity.
An L, Hu XW, Zhang S, Hu X, Song Z, Naz A, Zi Z, Wu J, Li C, Zou Y, He L, Zhu H
Scientific reports743251(2017 Feb)

Focal Adhesion Kinase-mediated Phosphorylation of Beclin1 Protein Suppresses Cardiomyocyte Autophagy and Initiates Hypertrophic Growth.
Cheng Z, Zhu Q, Dee R, Opheim Z, Mack CP, Cyr DM, Taylor JM
The Journal of biological chemistry292(6)2065-2079(2017 02)

Autophagic UVRAG Promotes UV-Induced Photolesion Repair by Activation of the CRL4(DDB2) E3 Ligase.
Yang Y, He S, Wang Q, Li F, Kwak MJ, Chen S, O'Connell D, Zhang T, Pirooz SD, Jeon Y, Chimge NO, Frenkel B, Choi Y, Aldrovandi GM, Oh BH, Yuan Z, Liang C
Molecular cell62(4)507-19(2016 05)

mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival.
Munson MJ, Allen GF, Toth R, Campbell DG, Lucocq JM, Ganley IG
The EMBO journal34(17)2272-90(2015 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

UVRAG is a regulator of CRL4(DDB2)-mediated nucleotide excision repair and its expression levels may influence melanoma predisposition.
Title: Autophagic UVRAG Promotes UV-Induced Photolesion Repair by Activation of the CRL4(DDB2) E3 Ligase.

tubulation requires mTOR activity, and we identified two direct mTOR phosphorylation sites on UVRAG (S550 and S571) that activate VPS34.
Title: mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival.

silencing of UVRAG significantly attenuated the antimicrobial effects of macrophages against M. tuberculosis.
Title: MicroRNA-125a Inhibits Autophagy Activation and Antimicrobial Responses during Mycobacterial Infection.

data provide novel insights into the control of autophagy in T cells and identify UVRAG as a new regulator of naive peripheral T-cell homeostasis.
Title: Autophagy-independent functions of UVRAG are essential for peripheral naive T-cell homeostasis.

EWSR1 is involved in the post-transcriptional regulation of Uvrag via a miRNA-dependent pathway, resulting in the deregulation of autophagy inhibition.
Title: Uvrag targeting by Mir125a and Mir351 modulates autophagy associated with Ewsr1 deficiency.

The following Uvrag gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Uvrag cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu89679	XM_030243116.1 Latest version!	Mus musculus UV radiation resistance associated gene (Uvrag), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu39964	XM_006508349.3 Latest version!	Mus musculus UV radiation resistance associated gene (Uvrag), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OMu18164	NM_178635.3 Latest version!	Mus musculus UV radiation resistance associated gene (Uvrag), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$412.30 $589.00
View Old Accession Versions >>
OMu39964	XM_006508349.2	Mus musculus UV radiation resistance associated gene (Uvrag), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Uvrag ( XM_006508349.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006508412.1 Mus musculus UV radiation resistance associated gene (Uvrag), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu39964
Clone ID Related Accession (Same CDS sequence)	XM_006508349.2 , XM_006508349.3
Accession Version	XM_006508349.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1968bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	UV radiation resistance associated protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006508349.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGAGCT GCCGTCTCAG CAGCGGCGTC TCCGACATCT CCGGAACATC GCTGCTCGGA 
ACATTGTTAA TAGAAATGGC CATCAGCTTC TGGATACCTA CTTCACTCTT CATTTGTGTG 
ATAATGAGAA AATCTTTAAA GAATCCGACG TGGAGGAGTC TTGACTTTGG AATAATGCCG 
GATCGTCTGG ATACATCTGT GTCCTGCTTT GTGGTGAAGA TTTGGGGTGG AAAGGAAGAG 
GCCTTTCAGC TGTTGATAGA GTGGAAAGTC TACCTGGATG GGCTGAAGTA CTTGGGACAG 
CAGATCCATG CCCGCAACCA GAATGAAATC ATTTTTGGGC TGAATGATGG CTACTACGGT 
GCTCCCTGTG AACACAAGGG TCATCCAAAC GCACAGAAGA ACCTCCTTCA GGTGGACCAG 
AACTGTGTTC GCAATTCTTA CGATGTCTTC TCTTTGCTGC GGCTTCATAG AGCCCAGTGT 
GCAATTAAAC AGACTCAGGT AACTGTTCAG AGACTTGGAA AGGAAATTGA AGAAAAACTA 
AGACTCACAT CGACAAGCAA TGAGCTGAAA AAAGAAAGTG AATGTCTGCG ATTGAAAATT 
TTGGTGCTTC GAAATGAACT GGAAAGACAG AAGAAAGCGC TGGGGCGGGA GGTGGCCTTC 
CTGCATAAGC AACAGATGGC TCTACAGGAC AAAGGAAGTG CATTTTCCAC TGAGCATGGC 
AAGCTCCAGC TGCAGAAGGA CTCCCTGAGT GAGCTGAGGA AGGAGTGTAC TGCCAAAAGG 
GAACTCTTTC TGAAGACTAA TGCTCAGTTG ACCATCCGCT GCAGGCAGCT ACTCTCAGAG 
CTGTCCTACA TTTACCCTAT TGATTTGAAT GAGAACAAGG ATTATTTTGT ATGTGGTGTC 
AAGTTGCCTA ATTCCGAGGA CTTCCAAGCA AAAGATGATG GAAGCATTGC CGTCGCCCTT 
GGTTACACTG CACATTTGGT CTCCATGATC TCCTTCTTCC TACAAGTACC CCTCAGGTAT 
CCCATAATTC ACAAGGGGTC CAGATCAACA ATCAAAGATA ACATCAACGA CAAGCTGACA 
GAAAAGGAGC GAGAGTTTCC ACTGTATCCA AAGGGAGGGG AGAAGCTGCA GTTTGACTAT 
GGTGTCTACC TTCTGAACAA GAACATAGCA CAGCTGAGAT ACCAGCATGG CCTGGGGACT 
CCAGACTTGA GGCAAACTCT TCCTAACCTG AAAAACTTCA TGGAGCACGG ACTGATGGTC 
AGGTGTGACA GACATCACAT CTCCAATGCC ATCCCTGTCC CGAAGAGACA AAGCTCCACG 
TTTGGGGGTG CAGATGGAGG CTTCTCTGCG GGTATCCCAT CACCAGATAA AGTCCATCGC 
AAGCGGGCCA GCTCAGAGAA CGAGAGACTC CAGTACAAAA CCCCACCTCC CAGCTACAAT 
TCAGCATTGA CACAGCCCGG GGTGGCCATG CCCACCTCGG GAGACTCTGA GAGAAAGGTC 
GCCCCTCTGT CCTCCTCCCT GGACACCTCC CTGGACTTCT CCAAAGAAAA CAAGAAAGCA 
GGAGTAGACC TGGGCAGCAG TGTGAGCGGA GACCACGGAA ACTCGGACTC CGGCCAAGAG 
CAGGGGGAAG CCCTGCCTGG GCACCTGGCA GCCGTGAATG GCACTGCACT GCCCAGCGAG 
CAGGCTGGCC CTGCCGGCAC CCTGCTGCCA GGCTCGTGCC ACCCGGCCCC CTCAGCTGAG 
CTCTGCTGTG CAGTGGAGCA AGCAGAGGAA ATCATCGGGC TGGAAGCCAC AGGCTTCACC 
TCGGGTGACC AGCTGGAGGC GCTCAGCTGC ATCCCGGTGG ACAGCGCAGT GGCAGTGGAG 
TGTGACGAGC AGGTGCTGGG GGAGTTTGAG GAGTTCTCTC GCAGGATCTA TGCCCTCAGC 
GAGAACGTGT CCAGCTTCCG CCGGCCTCGC AGGAGTTCCG ACAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006508412.1
CDS	313..2280
Translation	MWSCRLSSGVSDISGTSLLGTLLIEMAISFWIPTSLFICVIMRKSLKNPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKEEAFQLLIEWKVYLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPCEHKGHPNAQKNLLQVDQNCVRNSYDVFSLLRLHRAQCAIKQTQVTVQRLGKEIEEKLRLTSTSNELKKESECLRLKILVLRNELERQKKALGREVAFLHKQQMALQDKGSAFSTEHGKLQLQKDSLSELRKECTAKRELFLKTNAQLTIRCRQLLSELSYIYPIDLNENKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGSRSTIKDNINDKLTEKEREFPLYPKGGEKLQFDYGVYLLNKNIAQLRYQHGLGTPDLRQTLPNLKNFMEHGLMVRCDRHHISNAIPVPKRQSSTFGGADGGFSAGIPSPDKVHRKRASSENERLQYKTPPPSYNSALTQPGVAMPTSGDSERKVAPLSSSLDTSLDFSKENKKAGVDLGSSVSGDHGNSDSGQEQGEALPGHLAAVNGTALPSEQAGPAGTLLPGSCHPAPSAELCCAVEQAEEIIGLEATGFTSGDQLEALSCIPVDSAVAVECDEQVLGEFEEFSRRIYALSENVSSFRRPRRSSDK

Target ORF information:

RefSeq Version	XM_006508349.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus UV radiation resistance associated gene (Uvrag), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006508349.2

ORF Insert Sequence:

ATGTGGAGCT GCCGTCTCAG CAGCGGCGTC TCCGACATCT CCGGAACATC GCTGCTCGGA 
ACATTGTTAA TAGAAATGGC CATCAGCTTC TGGATACCTA CTTCACTCTT CATTTGTGTG 
ATAATGAGAA AATCTTTAAA GAATCCGACG TGGAGGAGTC TTGACTTTGG AATAATGCCG 
GATCGTCTGG ATACATCTGT GTCCTGCTTT GTGGTGAAGA TTTGGGGTGG AAAGGAAGAG 
GCCTTTCAGC TGTTGATAGA GTGGAAAGTC TACCTGGATG GGCTGAAGTA CTTGGGACAG 
CAGATCCATG CCCGCAACCA GAATGAAATC ATTTTTGGGC TGAATGATGG CTACTACGGT 
GCTCCCTGTG AACACAAGGG TCATCCAAAC GCACAGAAGA ACCTCCTTCA GGTGGACCAG 
AACTGTGTTC GCAATTCTTA CGATGTCTTC TCTTTGCTGC GGCTTCATAG AGCCCAGTGT 
GCAATTAAAC AGACTCAGGT AACTGTTCAG AGACTTGGAA AGGAAATTGA AGAAAAACTA 
AGACTCACAT CGACAAGCAA TGAGCTGAAA AAAGAAAGTG AATGTCTGCG ATTGAAAATT 
TTGGTGCTTC GAAATGAACT GGAAAGACAG AAGAAAGCGC TGGGGCGGGA GGTGGCCTTC 
CTGCATAAGC AACAGATGGC TCTACAGGAC AAAGGAAGTG CATTTTCCAC TGAGCATGGC 
AAGCTCCAGC TGCAGAAGGA CTCCCTGAGT GAGCTGAGGA AGGAGTGTAC TGCCAAAAGG 
GAACTCTTTC TGAAGACTAA TGCTCAGTTG ACCATCCGCT GCAGGCAGCT ACTCTCAGAG 
CTGTCCTACA TTTACCCTAT TGATTTGAAT GAGAACAAGG ATTATTTTGT ATGTGGTGTC 
AAGTTGCCTA ATTCCGAGGA CTTCCAAGCA AAAGATGATG GAAGCATTGC CGTCGCCCTT 
GGTTACACTG CACATTTGGT CTCCATGATC TCCTTCTTCC TACAAGTACC CCTCAGGTAT 
CCCATAATTC ACAAGGGGTC CAGATCAACA ATCAAAGATA ACATCAACGA CAAGCTGACA 
GAAAAGGAGC GAGAGTTTCC ACTGTATCCA AAGGGAGGGG AGAAGCTGCA GTTTGACTAT 
GGTGTCTACC TTCTGAACAA GAACATAGCA CAGCTGAGAT ACCAGCATGG CCTGGGGACT 
CCAGACTTGA GGCAAACTCT TCCTAACCTG AAAAACTTCA TGGAGCACGG ACTGATGGTC 
AGGTGTGACA GACATCACAT CTCCAATGCC ATCCCTGTCC CGAAGAGACA AAGCTCCACG 
TTTGGGGGTG CAGATGGAGG CTTCTCTGCG GGTATCCCAT CACCAGATAA AGTCCATCGC 
AAGCGGGCCA GCTCAGAGAA CGAGAGACTC CAGTACAAAA CCCCACCTCC CAGCTACAAT 
TCAGCATTGA CACAGCCCGG GGTGGCCATG CCCACCTCGG GAGACTCTGA GAGAAAGGTC 
GCCCCTCTGT CCTCCTCCCT GGACACCTCC CTGGACTTCT CCAAAGAAAA CAAGAAAGCA 
GGAGTAGACC TGGGCAGCAG TGTGAGCGGA GACCACGGAA ACTCGGACTC CGGCCAAGAG 
CAGGGGGAAG CCCTGCCTGG GCACCTGGCA GCCGTGAATG GCACTGCACT GCCCAGCGAG 
CAGGCTGGCC CTGCCGGCAC CCTGCTGCCA GGCTCGTGCC ACCCGGCCCC CTCAGCTGAG 
CTCTGCTGTG CAGTGGAGCA AGCAGAGGAA ATCATCGGGC TGGAAGCCAC AGGCTTCACC 
TCGGGTGACC AGCTGGAGGC GCTCAGCTGC ATCCCGGTGG ACAGCGCAGT GGCAGTGGAG 
TGTGACGAGC AGGTGCTGGG GGAGTTTGAG GAGTTCTCTC GCAGGATCTA TGCCCTCAGC 
GAGAACGTGT CCAGCTTCCG CCGGCCTCGC AGGAGTTCCG ACAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Uvrag ( XM_030243116.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030098976.1 Mus musculus UV radiation resistance associated gene (Uvrag), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu89679
Clone ID Related Accession (Same CDS sequence)	XM_030243116.1
Accession Version	XM_030243116.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1293bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	UV radiation resistance-associated protein isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCTAC AGGACAAAGG AAGTGCATTT TCCACTGAGC ATGGCAAGCT CCAGCTGCAG 
AAGGACTCCC TGAGTGAGCT GAGGAAGGAG TGTACTGCCA AAAGGGAACT CTTTCTGAAG 
ACTAATGCTC AGTTGACCAT CCGCTGCAGG CAGCTACTCT CAGAGCTGTC CTACATTTAC 
CCTATTGATT TGAATGAGAA CAAGGATTAT TTTGTATGTG GTGTCAAGTT GCCTAATTCC 
GAGGACTTCC AAGCAAAAGA TGATGGAAGC ATTGCCGTCG CCCTTGGTTA CACTGCACAT 
TTGGTCTCCA TGATCTCCTT CTTCCTACAA GTACCCCTCA GGTATCCCAT AATTCACAAG 
GGGTCCAGAT CAACAATCAA AGATAACATC AACGACAAGC TGACAGAAAA GGAGCGAGAG 
TTTCCACTGT ATCCAAAGGG AGGGGAGAAG CTGCAGTTTG ACTATGGTGT CTACCTTCTG 
AACAAGAACA TAGCACAGCT GAGATACCAG CATGGCCTGG GGACTCCAGA CTTGAGGCAA 
ACTCTTCCTA ACCTGAAAAA CTTCATGGAG CACGGACTGA TGGTCAGGTG TGACAGACAT 
CACATCTCCA ATGCCATCCC TGTCCCGAAG AGACAAAGCT CCACGTTTGG GGGTGCAGAT 
GGAGGCTTCT CTGCGGGTAT CCCATCACCA GATAAAGTCC ATCGCAAGCG GGCCAGCTCA 
GAGAACGAGA GACTCCAGTA CAAAACCCCA CCTCCCAGCT ACAATTCAGC ATTGACACAG 
CCCGGGGTGG CCATGCCCAC CTCGGGAGAC TCTGAGAGAA AGGTCGCCCC TCTGTCCTCC 
TCCCTGGACA CCTCCCTGGA CTTCTCCAAA GAAAACAAGA AAGCAGGAGT AGACCTGGGC 
AGCAGTGTGA GCGGAGACCA CGGAAACTCG GACTCCGGCC AAGAGCAGGG GGAAGCCCTG 
CCTGGGCACC TGGCAGCCGT GAATGGCACT GCACTGCCCA GCGAGCAGGC TGGCCCTGCC 
GGCACCCTGC TGCCAGGCTC GTGCCACCCG GCCCCCTCAG CTGAGCTCTG CTGTGCAGTG 
GAGCAAGCAG AGGAAATCAT CGGGCTGGAA GCCACAGGCT TCACCTCGGG TGACCAGCTG 
GAGGCGCTCA GCTGCATCCC GGTGGACAGC GCAGTGGCAG TGGAGTGTGA CGAGCAGGTG 
CTGGGGGAGT TTGAGGAGTT CTCTCGCAGG ATCTATGCCC TCAGCGAGAA CGTGTCCAGC 
TTCCGCCGGC CTCGCAGGAG TTCCGACAAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030098976.1
CDS	916..2208
Translation	MALQDKGSAFSTEHGKLQLQKDSLSELRKECTAKRELFLKTNAQLTIRCRQLLSELSYIYPIDLNENKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGSRSTIKDNINDKLTEKEREFPLYPKGGEKLQFDYGVYLLNKNIAQLRYQHGLGTPDLRQTLPNLKNFMEHGLMVRCDRHHISNAIPVPKRQSSTFGGADGGFSAGIPSPDKVHRKRASSENERLQYKTPPPSYNSALTQPGVAMPTSGDSERKVAPLSSSLDTSLDFSKENKKAGVDLGSSVSGDHGNSDSGQEQGEALPGHLAAVNGTALPSEQAGPAGTLLPGSCHPAPSAELCCAVEQAEEIIGLEATGFTSGDQLEALSCIPVDSAVAVECDEQVLGEFEEFSRRIYALSENVSSFRRPRRSSDK

Target ORF information:

RefSeq Version	XM_030243116.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus UV radiation resistance associated gene (Uvrag), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030243116.1

ORF Insert Sequence:

ATGGCTCTAC AGGACAAAGG AAGTGCATTT TCCACTGAGC ATGGCAAGCT CCAGCTGCAG 
AAGGACTCCC TGAGTGAGCT GAGGAAGGAG TGTACTGCCA AAAGGGAACT CTTTCTGAAG 
ACTAATGCTC AGTTGACCAT CCGCTGCAGG CAGCTACTCT CAGAGCTGTC CTACATTTAC 
CCTATTGATT TGAATGAGAA CAAGGATTAT TTTGTATGTG GTGTCAAGTT GCCTAATTCC 
GAGGACTTCC AAGCAAAAGA TGATGGAAGC ATTGCCGTCG CCCTTGGTTA CACTGCACAT 
TTGGTCTCCA TGATCTCCTT CTTCCTACAA GTACCCCTCA GGTATCCCAT AATTCACAAG 
GGGTCCAGAT CAACAATCAA AGATAACATC AACGACAAGC TGACAGAAAA GGAGCGAGAG 
TTTCCACTGT ATCCAAAGGG AGGGGAGAAG CTGCAGTTTG ACTATGGTGT CTACCTTCTG 
AACAAGAACA TAGCACAGCT GAGATACCAG CATGGCCTGG GGACTCCAGA CTTGAGGCAA 
ACTCTTCCTA ACCTGAAAAA CTTCATGGAG CACGGACTGA TGGTCAGGTG TGACAGACAT 
CACATCTCCA ATGCCATCCC TGTCCCGAAG AGACAAAGCT CCACGTTTGG GGGTGCAGAT 
GGAGGCTTCT CTGCGGGTAT CCCATCACCA GATAAAGTCC ATCGCAAGCG GGCCAGCTCA 
GAGAACGAGA GACTCCAGTA CAAAACCCCA CCTCCCAGCT ACAATTCAGC ATTGACACAG 
CCCGGGGTGG CCATGCCCAC CTCGGGAGAC TCTGAGAGAA AGGTCGCCCC TCTGTCCTCC 
TCCCTGGACA CCTCCCTGGA CTTCTCCAAA GAAAACAAGA AAGCAGGAGT AGACCTGGGC 
AGCAGTGTGA GCGGAGACCA CGGAAACTCG GACTCCGGCC AAGAGCAGGG GGAAGCCCTG 
CCTGGGCACC TGGCAGCCGT GAATGGCACT GCACTGCCCA GCGAGCAGGC TGGCCCTGCC 
GGCACCCTGC TGCCAGGCTC GTGCCACCCG GCCCCCTCAG CTGAGCTCTG CTGTGCAGTG 
GAGCAAGCAG AGGAAATCAT CGGGCTGGAA GCCACAGGCT TCACCTCGGG TGACCAGCTG 
GAGGCGCTCA GCTGCATCCC GGTGGACAGC GCAGTGGCAG TGGAGTGTGA CGAGCAGGTG 
CTGGGGGAGT TTGAGGAGTT CTCTCGCAGG ATCTATGCCC TCAGCGAGAA CGTGTCCAGC 
TTCCGCCGGC CTCGCAGGAG TTCCGACAAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Uvrag ( XM_006508349.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006508412.1 Mus musculus UV radiation resistance associated gene (Uvrag), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu39964
Clone ID Related Accession (Same CDS sequence)	XM_006508349.2 , XM_006508349.3
Accession Version	XM_006508349.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1968bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	UV radiation resistance-associated protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006508349.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGAGCT GCCGTCTCAG CAGCGGCGTC TCCGACATCT CCGGAACATC GCTGCTCGGA 
ACATTGTTAA TAGAAATGGC CATCAGCTTC TGGATACCTA CTTCACTCTT CATTTGTGTG 
ATAATGAGAA AATCTTTAAA GAATCCGACG TGGAGGAGTC TTGACTTTGG AATAATGCCG 
GATCGTCTGG ATACATCTGT GTCCTGCTTT GTGGTGAAGA TTTGGGGTGG AAAGGAAGAG 
GCCTTTCAGC TGTTGATAGA GTGGAAAGTC TACCTGGATG GGCTGAAGTA CTTGGGACAG 
CAGATCCATG CCCGCAACCA GAATGAAATC ATTTTTGGGC TGAATGATGG CTACTACGGT 
GCTCCCTGTG AACACAAGGG TCATCCAAAC GCACAGAAGA ACCTCCTTCA GGTGGACCAG 
AACTGTGTTC GCAATTCTTA CGATGTCTTC TCTTTGCTGC GGCTTCATAG AGCCCAGTGT 
GCAATTAAAC AGACTCAGGT AACTGTTCAG AGACTTGGAA AGGAAATTGA AGAAAAACTA 
AGACTCACAT CGACAAGCAA TGAGCTGAAA AAAGAAAGTG AATGTCTGCG ATTGAAAATT 
TTGGTGCTTC GAAATGAACT GGAAAGACAG AAGAAAGCGC TGGGGCGGGA GGTGGCCTTC 
CTGCATAAGC AACAGATGGC TCTACAGGAC AAAGGAAGTG CATTTTCCAC TGAGCATGGC 
AAGCTCCAGC TGCAGAAGGA CTCCCTGAGT GAGCTGAGGA AGGAGTGTAC TGCCAAAAGG 
GAACTCTTTC TGAAGACTAA TGCTCAGTTG ACCATCCGCT GCAGGCAGCT ACTCTCAGAG 
CTGTCCTACA TTTACCCTAT TGATTTGAAT GAGAACAAGG ATTATTTTGT ATGTGGTGTC 
AAGTTGCCTA ATTCCGAGGA CTTCCAAGCA AAAGATGATG GAAGCATTGC CGTCGCCCTT 
GGTTACACTG CACATTTGGT CTCCATGATC TCCTTCTTCC TACAAGTACC CCTCAGGTAT 
CCCATAATTC ACAAGGGGTC CAGATCAACA ATCAAAGATA ACATCAACGA CAAGCTGACA 
GAAAAGGAGC GAGAGTTTCC ACTGTATCCA AAGGGAGGGG AGAAGCTGCA GTTTGACTAT 
GGTGTCTACC TTCTGAACAA GAACATAGCA CAGCTGAGAT ACCAGCATGG CCTGGGGACT 
CCAGACTTGA GGCAAACTCT TCCTAACCTG AAAAACTTCA TGGAGCACGG ACTGATGGTC 
AGGTGTGACA GACATCACAT CTCCAATGCC ATCCCTGTCC CGAAGAGACA AAGCTCCACG 
TTTGGGGGTG CAGATGGAGG CTTCTCTGCG GGTATCCCAT CACCAGATAA AGTCCATCGC 
AAGCGGGCCA GCTCAGAGAA CGAGAGACTC CAGTACAAAA CCCCACCTCC CAGCTACAAT 
TCAGCATTGA CACAGCCCGG GGTGGCCATG CCCACCTCGG GAGACTCTGA GAGAAAGGTC 
GCCCCTCTGT CCTCCTCCCT GGACACCTCC CTGGACTTCT CCAAAGAAAA CAAGAAAGCA 
GGAGTAGACC TGGGCAGCAG TGTGAGCGGA GACCACGGAA ACTCGGACTC CGGCCAAGAG 
CAGGGGGAAG CCCTGCCTGG GCACCTGGCA GCCGTGAATG GCACTGCACT GCCCAGCGAG 
CAGGCTGGCC CTGCCGGCAC CCTGCTGCCA GGCTCGTGCC ACCCGGCCCC CTCAGCTGAG 
CTCTGCTGTG CAGTGGAGCA AGCAGAGGAA ATCATCGGGC TGGAAGCCAC AGGCTTCACC 
TCGGGTGACC AGCTGGAGGC GCTCAGCTGC ATCCCGGTGG ACAGCGCAGT GGCAGTGGAG 
TGTGACGAGC AGGTGCTGGG GGAGTTTGAG GAGTTCTCTC GCAGGATCTA TGCCCTCAGC 
GAGAACGTGT CCAGCTTCCG CCGGCCTCGC AGGAGTTCCG ACAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006508412.1
CDS	312..2279
Translation	MWSCRLSSGVSDISGTSLLGTLLIEMAISFWIPTSLFICVIMRKSLKNPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKEEAFQLLIEWKVYLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPCEHKGHPNAQKNLLQVDQNCVRNSYDVFSLLRLHRAQCAIKQTQVTVQRLGKEIEEKLRLTSTSNELKKESECLRLKILVLRNELERQKKALGREVAFLHKQQMALQDKGSAFSTEHGKLQLQKDSLSELRKECTAKRELFLKTNAQLTIRCRQLLSELSYIYPIDLNENKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGSRSTIKDNINDKLTEKEREFPLYPKGGEKLQFDYGVYLLNKNIAQLRYQHGLGTPDLRQTLPNLKNFMEHGLMVRCDRHHISNAIPVPKRQSSTFGGADGGFSAGIPSPDKVHRKRASSENERLQYKTPPPSYNSALTQPGVAMPTSGDSERKVAPLSSSLDTSLDFSKENKKAGVDLGSSVSGDHGNSDSGQEQGEALPGHLAAVNGTALPSEQAGPAGTLLPGSCHPAPSAELCCAVEQAEEIIGLEATGFTSGDQLEALSCIPVDSAVAVECDEQVLGEFEEFSRRIYALSENVSSFRRPRRSSDK

Target ORF information:

RefSeq Version	XM_006508349.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus UV radiation resistance associated gene (Uvrag), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006508349.3

ORF Insert Sequence:

ATGTGGAGCT GCCGTCTCAG CAGCGGCGTC TCCGACATCT CCGGAACATC GCTGCTCGGA 
ACATTGTTAA TAGAAATGGC CATCAGCTTC TGGATACCTA CTTCACTCTT CATTTGTGTG 
ATAATGAGAA AATCTTTAAA GAATCCGACG TGGAGGAGTC TTGACTTTGG AATAATGCCG 
GATCGTCTGG ATACATCTGT GTCCTGCTTT GTGGTGAAGA TTTGGGGTGG AAAGGAAGAG 
GCCTTTCAGC TGTTGATAGA GTGGAAAGTC TACCTGGATG GGCTGAAGTA CTTGGGACAG 
CAGATCCATG CCCGCAACCA GAATGAAATC ATTTTTGGGC TGAATGATGG CTACTACGGT 
GCTCCCTGTG AACACAAGGG TCATCCAAAC GCACAGAAGA ACCTCCTTCA GGTGGACCAG 
AACTGTGTTC GCAATTCTTA CGATGTCTTC TCTTTGCTGC GGCTTCATAG AGCCCAGTGT 
GCAATTAAAC AGACTCAGGT AACTGTTCAG AGACTTGGAA AGGAAATTGA AGAAAAACTA 
AGACTCACAT CGACAAGCAA TGAGCTGAAA AAAGAAAGTG AATGTCTGCG ATTGAAAATT 
TTGGTGCTTC GAAATGAACT GGAAAGACAG AAGAAAGCGC TGGGGCGGGA GGTGGCCTTC 
CTGCATAAGC AACAGATGGC TCTACAGGAC AAAGGAAGTG CATTTTCCAC TGAGCATGGC 
AAGCTCCAGC TGCAGAAGGA CTCCCTGAGT GAGCTGAGGA AGGAGTGTAC TGCCAAAAGG 
GAACTCTTTC TGAAGACTAA TGCTCAGTTG ACCATCCGCT GCAGGCAGCT ACTCTCAGAG 
CTGTCCTACA TTTACCCTAT TGATTTGAAT GAGAACAAGG ATTATTTTGT ATGTGGTGTC 
AAGTTGCCTA ATTCCGAGGA CTTCCAAGCA AAAGATGATG GAAGCATTGC CGTCGCCCTT 
GGTTACACTG CACATTTGGT CTCCATGATC TCCTTCTTCC TACAAGTACC CCTCAGGTAT 
CCCATAATTC ACAAGGGGTC CAGATCAACA ATCAAAGATA ACATCAACGA CAAGCTGACA 
GAAAAGGAGC GAGAGTTTCC ACTGTATCCA AAGGGAGGGG AGAAGCTGCA GTTTGACTAT 
GGTGTCTACC TTCTGAACAA GAACATAGCA CAGCTGAGAT ACCAGCATGG CCTGGGGACT 
CCAGACTTGA GGCAAACTCT TCCTAACCTG AAAAACTTCA TGGAGCACGG ACTGATGGTC 
AGGTGTGACA GACATCACAT CTCCAATGCC ATCCCTGTCC CGAAGAGACA AAGCTCCACG 
TTTGGGGGTG CAGATGGAGG CTTCTCTGCG GGTATCCCAT CACCAGATAA AGTCCATCGC 
AAGCGGGCCA GCTCAGAGAA CGAGAGACTC CAGTACAAAA CCCCACCTCC CAGCTACAAT 
TCAGCATTGA CACAGCCCGG GGTGGCCATG CCCACCTCGG GAGACTCTGA GAGAAAGGTC 
GCCCCTCTGT CCTCCTCCCT GGACACCTCC CTGGACTTCT CCAAAGAAAA CAAGAAAGCA 
GGAGTAGACC TGGGCAGCAG TGTGAGCGGA GACCACGGAA ACTCGGACTC CGGCCAAGAG 
CAGGGGGAAG CCCTGCCTGG GCACCTGGCA GCCGTGAATG GCACTGCACT GCCCAGCGAG 
CAGGCTGGCC CTGCCGGCAC CCTGCTGCCA GGCTCGTGCC ACCCGGCCCC CTCAGCTGAG 
CTCTGCTGTG CAGTGGAGCA AGCAGAGGAA ATCATCGGGC TGGAAGCCAC AGGCTTCACC 
TCGGGTGACC AGCTGGAGGC GCTCAGCTGC ATCCCGGTGG ACAGCGCAGT GGCAGTGGAG 
TGTGACGAGC AGGTGCTGGG GGAGTTTGAG GAGTTCTCTC GCAGGATCTA TGCCCTCAGC 
GAGAACGTGT CCAGCTTCCG CCGGCCTCGC AGGAGTTCCG ACAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Uvrag ( NM_178635.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_848750.3 Mus musculus UV radiation resistance associated gene (Uvrag), mRNA.

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CloneID	OMu18164
Clone ID Related Accession (Same CDS sequence)	NM_178635.3
Accession Version	NM_178635.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2097bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-21
Organism	Mus musculus(house mouse)
Product	UV radiation resistance-associated protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY024873.1, AK078085.1, AK030814.1 and BB530952.1. On Mar 22, 2008 this sequence version replaced NM_178635.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK154903.1, AK165185.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCTCCT GCGCCTCGCT CGGGGGCCCG GTGCCCCTGC CACCCCCGGG CCCGTCCGCC 
GCGCTGACGT CCGGTGCCCC CGCGCGGGCC CTGCATGTGG AGCTGCCGTC TCAGCAGCGG 
CGTCTCCGAC ATCTCCGGAA CATCGCTGCT CGGAACATTG TTAATAGAAA TGGCCATCAG 
CTTCTGGATA CCTACTTCAC TCTTCATTTG TGTGATAATG AGAAAATCTT TAAAGAATTT 
TATAGGAGTG AAGTGATTAA GAATTCCTTG AATCCGACGT GGAGGAGTCT TGACTTTGGA 
ATAATGCCGG ATCGTCTGGA TACATCTGTG TCCTGCTTTG TGGTGAAGAT TTGGGGTGGA 
AAGGAAGAGG CCTTTCAGCT GTTGATAGAG TGGAAAGTCT ACCTGGATGG GCTGAAGTAC 
TTGGGACAGC AGATCCATGC CCGCAACCAG AATGAAATCA TTTTTGGGCT GAATGATGGC 
TACTACGGTG CTCCCTGTGA ACACAAGGGT CATCCAAACG CACAGAAGAA CCTCCTTCAG 
GTGGACCAGA ACTGTGTTCG CAATTCTTAC GATGTCTTCT CTTTGCTGCG GCTTCATAGA 
GCCCAGTGTG CAATTAAACA GACTCAGGTA ACTGTTCAGA GACTTGGAAA GGAAATTGAA 
GAAAAACTAA GACTCACATC GACAAGCAAT GAGCTGAAAA AAGAAAGTGA ATGTCTGCGA 
TTGAAAATTT TGGTGCTTCG AAATGAACTG GAAAGACAGA AGAAAGCGCT GGGGCGGGAG 
GTGGCCTTCC TGCATAAGCA ACAGATGGCT CTACAGGACA AAGGAAGTGC ATTTTCCACT 
GAGCATGGCA AGCTCCAGCT GCAGAAGGAC TCCCTGAGTG AGCTGAGGAA GGAGTGTACT 
GCCAAAAGGG AACTCTTTCT GAAGACTAAT GCTCAGTTGA CCATCCGCTG CAGGCAGCTA 
CTCTCAGAGC TGTCCTACAT TTACCCTATT GATTTGAATG AGAACAAGGA TTATTTTGTA 
TGTGGTGTCA AGTTGCCTAA TTCCGAGGAC TTCCAAGCAA AAGATGATGG AAGCATTGCC 
GTCGCCCTTG GTTACACTGC ACATTTGGTC TCCATGATCT CCTTCTTCCT ACAAGTACCC 
CTCAGGTATC CCATAATTCA CAAGGGGTCC AGATCAACAA TCAAAGATAA CATCAACGAC 
AAGCTGACAG AAAAGGAGCG AGAGTTTCCA CTGTATCCAA AGGGAGGGGA GAAGCTGCAG 
TTTGACTATG GTGTCTACCT TCTGAACAAG AACATAGCAC AGCTGAGATA CCAGCATGGC 
CTGGGGACTC CAGACTTGAG GCAAACTCTT CCTAACCTGA AAAACTTCAT GGAGCACGGA 
CTGATGGTCA GGTGTGACAG ACATCACATC TCCAATGCCA TCCCTGTCCC GAAGAGACAA 
AGCTCCACGT TTGGGGGTGC AGATGGAGGC TTCTCTGCGG GTATCCCATC ACCAGATAAA 
GTCCATCGCA AGCGGGCCAG CTCAGAGAAC GAGAGACTCC AGTACAAAAC CCCACCTCCC 
AGCTACAATT CAGCATTGAC ACAGCCCGGG GTGGCCATGC CCACCTCGGG AGACTCTGAG 
AGAAAGGTCG CCCCTCTGTC CTCCTCCCTG GACACCTCCC TGGACTTCTC CAAAGAAAAC 
AAGAAAGCAG GAGTAGACCT GGGCAGCAGT GTGAGCGGAG ACCACGGAAA CTCGGACTCC 
GGCCAAGAGC AGGGGGAAGC CCTGCCTGGG CACCTGGCAG CCGTGAATGG CACTGCACTG 
CCCAGCGAGC AGGCTGGCCC TGCCGGCACC CTGCTGCCAG GCTCGTGCCA CCCGGCCCCC 
TCAGCTGAGC TCTGCTGTGC AGTGGAGCAA GCAGAGGAAA TCATCGGGCT GGAAGCCACA 
GGCTTCACCT CGGGTGACCA GCTGGAGGCG CTCAGCTGCA TCCCGGTGGA CAGCGCAGTG 
GCAGTGGAGT GTGACGAGCA GGTGCTGGGG GAGTTTGAGG AGTTCTCTCG CAGGATCTAT 
GCCCTCAGCG AGAACGTGTC CAGCTTCCGC CGGCCTCGCA GGAGTTCCGA CAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_848750.3
CDS	195..2291
Translation	MSSCASLGGPVPLPPPGPSAALTSGAPARALHVELPSQQRRLRHLRNIAARNIVNRNGHQLLDTYFTLHLCDNEKIFKEFYRSEVIKNSLNPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKEEAFQLLIEWKVYLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPCEHKGHPNAQKNLLQVDQNCVRNSYDVFSLLRLHRAQCAIKQTQVTVQRLGKEIEEKLRLTSTSNELKKESECLRLKILVLRNELERQKKALGREVAFLHKQQMALQDKGSAFSTEHGKLQLQKDSLSELRKECTAKRELFLKTNAQLTIRCRQLLSELSYIYPIDLNENKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGSRSTIKDNINDKLTEKEREFPLYPKGGEKLQFDYGVYLLNKNIAQLRYQHGLGTPDLRQTLPNLKNFMEHGLMVRCDRHHISNAIPVPKRQSSTFGGADGGFSAGIPSPDKVHRKRASSENERLQYKTPPPSYNSALTQPGVAMPTSGDSERKVAPLSSSLDTSLDFSKENKKAGVDLGSSVSGDHGNSDSGQEQGEALPGHLAAVNGTALPSEQAGPAGTLLPGSCHPAPSAELCCAVEQAEEIIGLEATGFTSGDQLEALSCIPVDSAVAVECDEQVLGEFEEFSRRIYALSENVSSFRRPRRSSDK

Target ORF information:

RefSeq Version	NM_178635.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus UV radiation resistance associated gene (Uvrag), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_178635.3

ORF Insert Sequence:

ATGAGCTCCT GCGCCTCGCT CGGGGGCCCG GTGCCCCTGC CACCCCCGGG CCCGTCCGCC 
GCGCTGACGT CCGGTGCCCC CGCGCGGGCC CTGCATGTGG AGCTGCCGTC TCAGCAGCGG 
CGTCTCCGAC ATCTCCGGAA CATCGCTGCT CGGAACATTG TTAATAGAAA TGGCCATCAG 
CTTCTGGATA CCTACTTCAC TCTTCATTTG TGTGATAATG AGAAAATCTT TAAAGAATTT 
TATAGGAGTG AAGTGATTAA GAATTCCTTG AATCCGACGT GGAGGAGTCT TGACTTTGGA 
ATAATGCCGG ATCGTCTGGA TACATCTGTG TCCTGCTTTG TGGTGAAGAT TTGGGGTGGA 
AAGGAAGAGG CCTTTCAGCT GTTGATAGAG TGGAAAGTCT ACCTGGATGG GCTGAAGTAC 
TTGGGACAGC AGATCCATGC CCGCAACCAG AATGAAATCA TTTTTGGGCT GAATGATGGC 
TACTACGGTG CTCCCTGTGA ACACAAGGGT CATCCAAACG CACAGAAGAA CCTCCTTCAG 
GTGGACCAGA ACTGTGTTCG CAATTCTTAC GATGTCTTCT CTTTGCTGCG GCTTCATAGA 
GCCCAGTGTG CAATTAAACA GACTCAGGTA ACTGTTCAGA GACTTGGAAA GGAAATTGAA 
GAAAAACTAA GACTCACATC GACAAGCAAT GAGCTGAAAA AAGAAAGTGA ATGTCTGCGA 
TTGAAAATTT TGGTGCTTCG AAATGAACTG GAAAGACAGA AGAAAGCGCT GGGGCGGGAG 
GTGGCCTTCC TGCATAAGCA ACAGATGGCT CTACAGGACA AAGGAAGTGC ATTTTCCACT 
GAGCATGGCA AGCTCCAGCT GCAGAAGGAC TCCCTGAGTG AGCTGAGGAA GGAGTGTACT 
GCCAAAAGGG AACTCTTTCT GAAGACTAAT GCTCAGTTGA CCATCCGCTG CAGGCAGCTA 
CTCTCAGAGC TGTCCTACAT TTACCCTATT GATTTGAATG AGAACAAGGA TTATTTTGTA 
TGTGGTGTCA AGTTGCCTAA TTCCGAGGAC TTCCAAGCAA AAGATGATGG AAGCATTGCC 
GTCGCCCTTG GTTACACTGC ACATTTGGTC TCCATGATCT CCTTCTTCCT ACAAGTACCC 
CTCAGGTATC CCATAATTCA CAAGGGGTCC AGATCAACAA TCAAAGATAA CATCAACGAC 
AAGCTGACAG AAAAGGAGCG AGAGTTTCCA CTGTATCCAA AGGGAGGGGA GAAGCTGCAG 
TTTGACTATG GTGTCTACCT TCTGAACAAG AACATAGCAC AGCTGAGATA CCAGCATGGC 
CTGGGGACTC CAGACTTGAG GCAAACTCTT CCTAACCTGA AAAACTTCAT GGAGCACGGA 
CTGATGGTCA GGTGTGACAG ACATCACATC TCCAATGCCA TCCCTGTCCC GAAGAGACAA 
AGCTCCACGT TTGGGGGTGC AGATGGAGGC TTCTCTGCGG GTATCCCATC ACCAGATAAA 
GTCCATCGCA AGCGGGCCAG CTCAGAGAAC GAGAGACTCC AGTACAAAAC CCCACCTCCC 
AGCTACAATT CAGCATTGAC ACAGCCCGGG GTGGCCATGC CCACCTCGGG AGACTCTGAG 
AGAAAGGTCG CCCCTCTGTC CTCCTCCCTG GACACCTCCC TGGACTTCTC CAAAGAAAAC 
AAGAAAGCAG GAGTAGACCT GGGCAGCAGT GTGAGCGGAG ACCACGGAAA CTCGGACTCC 
GGCCAAGAGC AGGGGGAAGC CCTGCCTGGG CACCTGGCAG CCGTGAATGG CACTGCACTG 
CCCAGCGAGC AGGCTGGCCC TGCCGGCACC CTGCTGCCAG GCTCGTGCCA CCCGGCCCCC 
TCAGCTGAGC TCTGCTGTGC AGTGGAGCAA GCAGAGGAAA TCATCGGGCT GGAAGCCACA 
GGCTTCACCT CGGGTGACCA GCTGGAGGCG CTCAGCTGCA TCCCGGTGGA CAGCGCAGTG 
GCAGTGGAGT GTGACGAGCA GGTGCTGGGG GAGTTTGAGG AGTTCTCTCG CAGGATCTAT 
GCCCTCAGCG AGAACGTGTC CAGCTTCCGC CGGCCTCGCA GGAGTTCCGA CAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

UVRAG Deficiency Exacerbates Doxorubicin-Induced Cardiotoxicity.
Scientific reports743251(2017 Feb)
An L,Hu XW,Zhang S,Hu X,Song Z,Naz A,Zi Z,Wu J,Li C,Zou Y,He L,Zhu H

Focal Adhesion Kinase-mediated Phosphorylation of Beclin1 Protein Suppresses Cardiomyocyte Autophagy and Initiates Hypertrophic Growth.
The Journal of biological chemistry292(6)2065-2079(2017 02)
Cheng Z,Zhu Q,Dee R,Opheim Z,Mack CP,Cyr DM,Taylor JM

Autophagic UVRAG Promotes UV-Induced Photolesion Repair by Activation of the CRL4(DDB2) E3 Ligase.
Molecular cell62(4)507-19(2016 05)
Yang Y,He S,Wang Q,Li F,Kwak MJ,Chen S,O'Connell D,Zhang T,Pirooz SD,Jeon Y,Chimge NO,Frenkel B,Choi Y,Aldrovandi GM,Oh BH,Yuan Z,Liang C

mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival.
The EMBO journal34(17)2272-90(2015 Sep)
Munson MJ,Allen GF,Toth R,Campbell DG,Lucocq JM,Ganley IG

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Uvrag cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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