Uvrag cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Uvrag
Entrez Gene ID	308846
Full Name	UV radiation resistance associated
General protein information	Preferred Names UV radiation resistance associated Names UV radiation resistance-associated gene protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q32

mRNA and Protein(s)

mRNA	Protein	Name
XM_006229763.2	XP_006229825.1	UV radiation resistance-associated gene protein isoform X1
NM_001107536.1	NP_001101006.1	UV radiation resistance-associated gene protein

Pathways from BioSystems

Homologies

	UVRAG	XP_001086725.1
Canis lupus familiaris (dog)	UVRAG	XP_849891.1
Mus musculus (house mouse)	Uvrag	NP_848750.3
Danio rerio (zebrafish)	uvrag	NP_957363.1
Xenopus tropicalis (tropical clawed frog)	uvrag	XP_002941209.2
Bos taurus (cattle)	UVRAG	NP_001179955.1
Rattus norvegicus (Norway rat)	Uvrag	NP_001101006.1
Homo sapiens (human)	UVRAG	NP_003360.2
Pan troglodytes (chimpanzee)	UVRAG	XP_508649.3
Gallus gallus (chicken)	UVRAG	NP_001026010.1

Gene Ontology
Bibliography

Related articles in PubMed

Pacer Mediates the Function of Class III PI3K and HOPS Complexes in Autophagosome Maturation by Engaging Stx17.
Cheng X, Ma X, Ding X, Li L, Jiang X, Shen Z, Chen S, Liu W, Gong W, Sun Q
Molecular cell65(6)1029-1043.e5(2017 Mar)

UVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREs.
Pirooz SD, He S, Zhang T, Zhang X, Zhao Z, Oh S, O'Connell D, Khalilzadeh P, Amini-Bavil-Olyaee S, Farzan M, Liang C
Proceedings of the National Academy of Sciences of the United States of America111(7)2716-21(2014 Feb)

PtdIns(3)P-bound UVRAG coordinates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin?1 complex.
He S, Ni D, Ma B, Lee JH, Zhang T, Ghozalli I, Pirooz SD, Zhao Z, Bharatham N, Li B, Oh S, Lee WH, Takahashi Y, Wang HG, Minassian A, Feng P, Deretic V, Pepperkok R, Tagaya M, Yoon HS, Liang C
Nature cell biology15(10)1206-1219(2013 Oct)

A dual role for UVRAG in maintaining chromosomal stability independent of autophagy.
Zhao Z, Oh S, Li D, Ni D, Pirooz SD, Lee JH, Yang S, Lee JY, Ghozalli I, Costanzo V, Stark JM, Liang C
Developmental cell22(5)1001-16(2012 May)

Receptor signaling lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation resistance-associated gene (UVRAG) complex.
Ma C, Wang N, Detre C, Wang G, O'Keeffe M, Terhorst C
The Journal of biological chemistry287(22)18359-65(2012 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In cultured hippocampal neurons, MAP2 and p63 were found to concomitantly compartmentalize to the dendritic processes during neuronal differentiation.
Title: Interaction of microtubule-associated protein-2 and p63: a new link between microtubules and rough endoplasmic reticulum membranes in neurons.

The following Uvrag gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Uvrag cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03876	NM_001107536.1 Latest version!	Rattus norvegicus UV radiation resistance associated (Uvrag), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
ORa23137	XM_006229763.2 Latest version!	Rattus norvegicus UV radiation resistance associated gene (Uvrag), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Uvrag ( NM_001107536.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101006.1 Rattus norvegicus UV radiation resistance associated (Uvrag), mRNA.

Price & Availability↑

CloneID	ORa03876
Clone ID Related Accession (Same CDS sequence)	NM_001107536.1
Accession Version	NM_001107536.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1398bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Rattus norvegicus(Norway rat)
Product	UV radiation resistance-associated gene protein
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473956.2. On or before Oct 4, 2007 this sequence version replaced XM_218951.4, XM_001065167.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN01906352 [ECO:0000350] ##Evidence-Data-END##

ATGAGCTCCT GCGCCTCGCT CGGGGGCCCG GTGCCCCTGC CACCCCCGGG CCCGTCCGCC 
GCGCTGACAC CGGGTGCCCC CACGCGGGCC CTGCATGTGG AGCTGCCGTC TCAGCAGCGG 
CGTCTGCGTC ATCTCCGGAA CATTGCTGCT CGGAACATTG TTAACAGAAA TGGCCATCAG 
CTTCTGGATA CCTACTTCAC TCTTCATTTG TGTGATAACG AGAAGATCTG TAAAGAATTT 
TATAGGAGTG AAGTGATTAA GAATTCCTTG AATCCAACGT GGAGGAGTCT TGACTTTGGA 
ATAATGCCGG ACCGTCTGGA TACATCTGTG TCCTGCTTTG TGGTGAAGAT TTGGGGTGGA 
AAGGAAGAGG CCTATCAGCT GTTGATAGAG TGGAAAGTCT ACTTGGATGG GCTGAAGTAC 
TTGGGTCAGC AGATCCATGC CCGCAACCAG AATGAAATCA TTTTTGGGCT GAACGATGGC 
TACTACGGTG CTCCATTTGA ACACAAGGCT CATCCAAATG CACAGAAGAA CCTCCTTCAG 
GTGGACCAGA ACTGTGTTCG CAATTCCTAT GATGTGTTTT CTTTGCTGCG GCTTCATAGA 
GCCCAGTGTG CAATTAAACA GACTCAGGTA ACTGTTCAGA GAATTGGAAA GGAAATTGAA 
GAAAAACTAA GACTCACATC GACAAGCAAT GAGCTGAAAA AAGAAAGTGA ATGTCTGCGA 
TTAAAAATTT TGGTGCTTCG AAATGAACTG GAAAGACAGA AGAAAGCTCT GGGACGGGAG 
GTGGCCTTCC TGCATAAGCA ACAAATGGCT CTACAAGACA AAGGAAGTGC ATTTGCCGCG 
GAGCACGCGA AGCTTCAGCT GCAGAAGGAA TCGCTGAGGG AGCTGAGGAA GGAGTGCACC 
GCCAAAAGAG AACTCTTTCT GAAGACAAAC GCTCAGCTGA CCATCCGCTG CAGGCAGTTA 
CTCTCGGAGC TGTCCTACAT TTACCCTATT GATCTGAATG AGCATAAGGA TTATTTTGTA 
TGTGGTGTCA AGTTGCCTAA TTCCGAGGAC TTCCAAGCAA AAGATGATGG AAGCATTGCC 
GTCGCCCTTG GTTACACTGC ACATTTGGTC TCCATGATCT CCTTCTTCCT ACAAGTACCC 
CTCAGATATC CCATAATTCA TAAGGGGTCC AGATCAACCA TCAAAGATAA CATCAACGAC 
AAGCTGACAG AAAAGGAGAG AGAGTTTCCA CTGTATCCAA AGGGAGGGGA GAAGCTGCAG 
TTTGATTATG GTGTCTACCT TCTGAACAAG AACATAGCAC AGCTGAGATA CCAGCACGGC 
CTGGGGACTC CAGACTTGAG GCAAACTCTT CCTAACCTGA AAAACTTCAT GGAGCACGGA 
CTGATGGTCA GATGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101006.1
CDS	181..1578
Translation	MSSCASLGGPVPLPPPGPSAALTPGAPTRALHVELPSQQRRLRHLRNIAARNIVNRNGHQLLDTYFTLHLCDNEKICKEFYRSEVIKNSLNPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKEEAYQLLIEWKVYLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPFEHKAHPNAQKNLLQVDQNCVRNSYDVFSLLRLHRAQCAIKQTQVTVQRIGKEIEEKLRLTSTSNELKKESECLRLKILVLRNELERQKKALGREVAFLHKQQMALQDKGSAFAAEHAKLQLQKESLRELRKECTAKRELFLKTNAQLTIRCRQLLSELSYIYPIDLNEHKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGSRSTIKDNINDKLTEKEREFPLYPKGGEKLQFDYGVYLLNKNIAQLRYQHGLGTPDLRQTLPNLKNFMEHGLMVRW

Target ORF information:

RefSeq Version	NM_001107536.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus UV radiation resistance associated (Uvrag), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107536.1

ORF Insert Sequence:

ATGAGCTCCT GCGCCTCGCT CGGGGGCCCG GTGCCCCTGC CACCCCCGGG CCCGTCCGCC 
GCGCTGACAC CGGGTGCCCC CACGCGGGCC CTGCATGTGG AGCTGCCGTC TCAGCAGCGG 
CGTCTGCGTC ATCTCCGGAA CATTGCTGCT CGGAACATTG TTAACAGAAA TGGCCATCAG 
CTTCTGGATA CCTACTTCAC TCTTCATTTG TGTGATAACG AGAAGATCTG TAAAGAATTT 
TATAGGAGTG AAGTGATTAA GAATTCCTTG AATCCAACGT GGAGGAGTCT TGACTTTGGA 
ATAATGCCGG ACCGTCTGGA TACATCTGTG TCCTGCTTTG TGGTGAAGAT TTGGGGTGGA 
AAGGAAGAGG CCTATCAGCT GTTGATAGAG TGGAAAGTCT ACTTGGATGG GCTGAAGTAC 
TTGGGTCAGC AGATCCATGC CCGCAACCAG AATGAAATCA TTTTTGGGCT GAACGATGGC 
TACTACGGTG CTCCATTTGA ACACAAGGCT CATCCAAATG CACAGAAGAA CCTCCTTCAG 
GTGGACCAGA ACTGTGTTCG CAATTCCTAT GATGTGTTTT CTTTGCTGCG GCTTCATAGA 
GCCCAGTGTG CAATTAAACA GACTCAGGTA ACTGTTCAGA GAATTGGAAA GGAAATTGAA 
GAAAAACTAA GACTCACATC GACAAGCAAT GAGCTGAAAA AAGAAAGTGA ATGTCTGCGA 
TTAAAAATTT TGGTGCTTCG AAATGAACTG GAAAGACAGA AGAAAGCTCT GGGACGGGAG 
GTGGCCTTCC TGCATAAGCA ACAAATGGCT CTACAAGACA AAGGAAGTGC ATTTGCCGCG 
GAGCACGCGA AGCTTCAGCT GCAGAAGGAA TCGCTGAGGG AGCTGAGGAA GGAGTGCACC 
GCCAAAAGAG AACTCTTTCT GAAGACAAAC GCTCAGCTGA CCATCCGCTG CAGGCAGTTA 
CTCTCGGAGC TGTCCTACAT TTACCCTATT GATCTGAATG AGCATAAGGA TTATTTTGTA 
TGTGGTGTCA AGTTGCCTAA TTCCGAGGAC TTCCAAGCAA AAGATGATGG AAGCATTGCC 
GTCGCCCTTG GTTACACTGC ACATTTGGTC TCCATGATCT CCTTCTTCCT ACAAGTACCC 
CTCAGATATC CCATAATTCA TAAGGGGTCC AGATCAACCA TCAAAGATAA CATCAACGAC 
AAGCTGACAG AAAAGGAGAG AGAGTTTCCA CTGTATCCAA AGGGAGGGGA GAAGCTGCAG 
TTTGATTATG GTGTCTACCT TCTGAACAAG AACATAGCAC AGCTGAGATA CCAGCACGGC 
CTGGGGACTC CAGACTTGAG GCAAACTCTT CCTAACCTGA AAAACTTCAT GGAGCACGGA 
CTGATGGTCA GATGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Uvrag ( XM_006229763.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006229825.1 Rattus norvegicus UV radiation resistance associated gene (Uvrag), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa23137
Clone ID Related Accession (Same CDS sequence)	XM_006229763.2
Accession Version	XM_006229763.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2097bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	UV radiation resistance-associated gene protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006229763.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCTCCT GCGCCTCGCT CGGGGGCCCG GTGCCCCTGC CACCCCCGGG CCCGTCCGCC 
GCGCTGACAC CGGGTGCCCC CACGCGGGCC CTGCATGTGG AGCTGCCGTC TCAGCAGCGG 
CGTCTGCGTC ATCTCCGGAA CATTGCTGCT CGGAACATTG TTAACAGAAA TGGCCATCAG 
CTTCTGGATA CCTACTTCAC TCTTCATTTG TGTGATAACG AGAAGATCTG TAAAGAATTT 
TATAGGAGTG AAGTGATTAA GAATTCCTTG AATCCAACGT GGAGGAGTCT TGACTTTGGA 
ATAATGCCGG ACCGTCTGGA TACATCTGTG TCCTGCTTTG TGGTGAAGAT TTGGGGTGGA 
AAGGAAGAGG CCTATCAGCT GTTGATAGAG TGGAAAGTCT ACTTGGATGG GCTGAAGTAC 
TTGGGTCAGC AGATCCATGC CCGCAACCAG AATGAAATCA TTTTTGGGCT GAACGATGGC 
TACTACGGTG CTCCATTTGA ACACAAGGCT CATCCAAATG CACAGAAGAA CCTCCTTCAG 
GTGGACCAGA ACTGTGTTCG CAATTCCTAT GATGTGTTTT CTTTGCTGCG GCTTCATAGA 
GCCCAGTGTG CAATTAAACA GACTCAGGTA ACTGTTCAGA GAATTGGAAA GGAAATTGAA 
GAAAAACTAA GACTCACATC GACAAGCAAT GAGCTGAAAA AAGAAAGTGA ATGTCTGCGA 
TTAAAAATTT TGGTGCTTCG AAATGAACTG GAAAGACAGA AGAAAGCTCT GGGACGGGAG 
GTGGCCTTCC TGCATAAGCA ACAAATGGCT CTACAAGACA AAGGAAGTGC ATTTGCCGCG 
GAGCACGCGA AGCTTCAGCT GCAGAAGGAA TCGCTGAGGG AGCTGAGGAA GGAGTGCACC 
GCCAAAAGAG AACTCTTTCT GAAGACAAAC GCTCAGCTGA CCATCCGCTG CAGGCAGTTA 
CTCTCGGAGC TGTCCTACAT TTACCCTATT GATCTGAATG AGCATAAGGA TTATTTTGTA 
TGTGGTGTCA AGTTGCCTAA TTCCGAGGAC TTCCAAGCAA AAGATGATGG AAGCATTGCC 
GTCGCCCTTG GTTACACTGC ACATTTGGTC TCCATGATCT CCTTCTTCCT ACAAGTACCC 
CTCAGATATC CCATAATTCA TAAGGGGTCC AGATCAACCA TCAAAGATAA CATCAACGAC 
AAGCTGACAG AAAAGGAGAG AGAGTTTCCA CTGTATCCAA AGGGAGGGGA GAAGCTGCAG 
TTTGATTATG GTGTCTACCT TCTGAACAAG AACATAGCAC AGCTGAGATA CCAGCACGGC 
CTGGGGACTC CAGACTTGAG GCAAACTCTT CCTAACCTGA AAAACTTCAT GGAGCACGGA 
CTGATGGTCA GATGTGACAG ACATCACATC TCCAGTGCCA TCCCTGTTCC GAAGAGACAG 
AGCTCCACGT TTCGGGGTGC AGATGTAGGC CTCTCTACGG GTGTCCCTTC ACCAGATAAC 
GTACATCGAA AACGGGCCAG CTCAGAGAAT GAGAGACTCC AGTACAAAAC CCCTCCTCCC 
AGCTACAACT CAGCATTGAC ACAGCACGGG GTGGCCATGC CCACCTTGGG AGACTCTGAG 
AGGAAGGTCA CCCCACTGTC CTCCTCCCTG GACACCTCCT TGGACTTCTC CAAAGAAAGT 
AAGAAAACAG GAGTAGACCT GGGCAACAGT GTAAGTGGAG ACCACAGAAA TGTGGACTCC 
AGCCAAGAAC AAGGGGAAGC CCTGCCTGGG CACCTGGCCA CCATAAATGG CACTGCGCTT 
CCCAGCGAGC AGCCTGGCCC TGCCGGCACC CTGCTGCCAG GCCTGTGCCA CCCGGCCCCC 
TCAGCCGAGC TCTGCTGTGC AGTGGAGCAA GCAGAAGAAA TTATCGGGCT GGAAGCCACA 
GGCTTCACGT CAGGCGACCA GCTCGAAGCA CTCAGCTGCA TCCCGGTGGA CAGCGCGGTG 
GCGGTGGAGT GTGACGAGCA GGTGCTGGGG GAGTTTGAGG AGTTCTCTCG GAGGATCTAC 
GCCCTCAGCG AAAACGTGTC CAGCTTCCGC CGGCCTCGCA GGAGTTCTGA CAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006229825.1
CDS	179..2275
Translation	MSSCASLGGPVPLPPPGPSAALTPGAPTRALHVELPSQQRRLRHLRNIAARNIVNRNGHQLLDTYFTLHLCDNEKICKEFYRSEVIKNSLNPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKEEAYQLLIEWKVYLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPFEHKAHPNAQKNLLQVDQNCVRNSYDVFSLLRLHRAQCAIKQTQVTVQRIGKEIEEKLRLTSTSNELKKESECLRLKILVLRNELERQKKALGREVAFLHKQQMALQDKGSAFAAEHAKLQLQKESLRELRKECTAKRELFLKTNAQLTIRCRQLLSELSYIYPIDLNEHKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGSRSTIKDNINDKLTEKEREFPLYPKGGEKLQFDYGVYLLNKNIAQLRYQHGLGTPDLRQTLPNLKNFMEHGLMVRCDRHHISSAIPVPKRQSSTFRGADVGLSTGVPSPDNVHRKRASSENERLQYKTPPPSYNSALTQHGVAMPTLGDSERKVTPLSSSLDTSLDFSKESKKTGVDLGNSVSGDHRNVDSSQEQGEALPGHLATINGTALPSEQPGPAGTLLPGLCHPAPSAELCCAVEQAEEIIGLEATGFTSGDQLEALSCIPVDSAVAVECDEQVLGEFEEFSRRIYALSENVSSFRRPRRSSDK

Target ORF information:

RefSeq Version	XM_006229763.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus UV radiation resistance associated gene (Uvrag), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006229763.2

ORF Insert Sequence:

ATGAGCTCCT GCGCCTCGCT CGGGGGCCCG GTGCCCCTGC CACCCCCGGG CCCGTCCGCC 
GCGCTGACAC CGGGTGCCCC CACGCGGGCC CTGCATGTGG AGCTGCCGTC TCAGCAGCGG 
CGTCTGCGTC ATCTCCGGAA CATTGCTGCT CGGAACATTG TTAACAGAAA TGGCCATCAG 
CTTCTGGATA CCTACTTCAC TCTTCATTTG TGTGATAACG AGAAGATCTG TAAAGAATTT 
TATAGGAGTG AAGTGATTAA GAATTCCTTG AATCCAACGT GGAGGAGTCT TGACTTTGGA 
ATAATGCCGG ACCGTCTGGA TACATCTGTG TCCTGCTTTG TGGTGAAGAT TTGGGGTGGA 
AAGGAAGAGG CCTATCAGCT GTTGATAGAG TGGAAAGTCT ACTTGGATGG GCTGAAGTAC 
TTGGGTCAGC AGATCCATGC CCGCAACCAG AATGAAATCA TTTTTGGGCT GAACGATGGC 
TACTACGGTG CTCCATTTGA ACACAAGGCT CATCCAAATG CACAGAAGAA CCTCCTTCAG 
GTGGACCAGA ACTGTGTTCG CAATTCCTAT GATGTGTTTT CTTTGCTGCG GCTTCATAGA 
GCCCAGTGTG CAATTAAACA GACTCAGGTA ACTGTTCAGA GAATTGGAAA GGAAATTGAA 
GAAAAACTAA GACTCACATC GACAAGCAAT GAGCTGAAAA AAGAAAGTGA ATGTCTGCGA 
TTAAAAATTT TGGTGCTTCG AAATGAACTG GAAAGACAGA AGAAAGCTCT GGGACGGGAG 
GTGGCCTTCC TGCATAAGCA ACAAATGGCT CTACAAGACA AAGGAAGTGC ATTTGCCGCG 
GAGCACGCGA AGCTTCAGCT GCAGAAGGAA TCGCTGAGGG AGCTGAGGAA GGAGTGCACC 
GCCAAAAGAG AACTCTTTCT GAAGACAAAC GCTCAGCTGA CCATCCGCTG CAGGCAGTTA 
CTCTCGGAGC TGTCCTACAT TTACCCTATT GATCTGAATG AGCATAAGGA TTATTTTGTA 
TGTGGTGTCA AGTTGCCTAA TTCCGAGGAC TTCCAAGCAA AAGATGATGG AAGCATTGCC 
GTCGCCCTTG GTTACACTGC ACATTTGGTC TCCATGATCT CCTTCTTCCT ACAAGTACCC 
CTCAGATATC CCATAATTCA TAAGGGGTCC AGATCAACCA TCAAAGATAA CATCAACGAC 
AAGCTGACAG AAAAGGAGAG AGAGTTTCCA CTGTATCCAA AGGGAGGGGA GAAGCTGCAG 
TTTGATTATG GTGTCTACCT TCTGAACAAG AACATAGCAC AGCTGAGATA CCAGCACGGC 
CTGGGGACTC CAGACTTGAG GCAAACTCTT CCTAACCTGA AAAACTTCAT GGAGCACGGA 
CTGATGGTCA GATGTGACAG ACATCACATC TCCAGTGCCA TCCCTGTTCC GAAGAGACAG 
AGCTCCACGT TTCGGGGTGC AGATGTAGGC CTCTCTACGG GTGTCCCTTC ACCAGATAAC 
GTACATCGAA AACGGGCCAG CTCAGAGAAT GAGAGACTCC AGTACAAAAC CCCTCCTCCC 
AGCTACAACT CAGCATTGAC ACAGCACGGG GTGGCCATGC CCACCTTGGG AGACTCTGAG 
AGGAAGGTCA CCCCACTGTC CTCCTCCCTG GACACCTCCT TGGACTTCTC CAAAGAAAGT 
AAGAAAACAG GAGTAGACCT GGGCAACAGT GTAAGTGGAG ACCACAGAAA TGTGGACTCC 
AGCCAAGAAC AAGGGGAAGC CCTGCCTGGG CACCTGGCCA CCATAAATGG CACTGCGCTT 
CCCAGCGAGC AGCCTGGCCC TGCCGGCACC CTGCTGCCAG GCCTGTGCCA CCCGGCCCCC 
TCAGCCGAGC TCTGCTGTGC AGTGGAGCAA GCAGAAGAAA TTATCGGGCT GGAAGCCACA 
GGCTTCACGT CAGGCGACCA GCTCGAAGCA CTCAGCTGCA TCCCGGTGGA CAGCGCGGTG 
GCGGTGGAGT GTGACGAGCA GGTGCTGGGG GAGTTTGAGG AGTTCTCTCG GAGGATCTAC 
GCCCTCAGCG AAAACGTGTC CAGCTTCCGC CGGCCTCGCA GGAGTTCTGA CAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Pacer Mediates the Function of Class III PI3K and HOPS Complexes in Autophagosome Maturation by Engaging Stx17.
Molecular cell65(6)1029-1043.e5(2017 Mar)
Cheng X,Ma X,Ding X,Li L,Jiang X,Shen Z,Chen S,Liu W,Gong W,Sun Q

UVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREs.
Proceedings of the National Academy of Sciences of the United States of America111(7)2716-21(2014 Feb)
Pirooz SD,He S,Zhang T,Zhang X,Zhao Z,Oh S,O'Connell D,Khalilzadeh P,Amini-Bavil-Olyaee S,Farzan M,Liang C

PtdIns(3)P-bound UVRAG coordinates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin?1 complex.
Nature cell biology15(10)1206-1219(2013 Oct)
He S,Ni D,Ma B,Lee JH,Zhang T,Ghozalli I,Pirooz SD,Zhao Z,Bharatham N,Li B,Oh S,Lee WH,Takahashi Y,Wang HG,Minassian A,Feng P,Deretic V,Pepperkok R,Tagaya M,Yoon HS,Liang C

A dual role for UVRAG in maintaining chromosomal stability independent of autophagy.
Developmental cell22(5)1001-16(2012 May)
Zhao Z,Oh S,Li D,Ni D,Pirooz SD,Lee JH,Yang S,Lee JY,Ghozalli I,Costanzo V,Stark JM,Liang C

Receptor signaling lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation resistance-associated gene (UVRAG) complex.
The Journal of biological chemistry287(22)18359-65(2012 May)
Ma C,Wang N,Detre C,Wang G,O'Keeffe M,Terhorst C

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Uvrag cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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