Slc39a4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc39a4
Entrez Gene ID	72027
Full Name	solute carrier family 39 (zinc transporter), member 4
Synonyms	1600025H15Rik,AU041686,AWMS2,ZIP4
General protein information	Preferred Names solute carrier family 39 (zinc transporter), member 4 Names zinc transporter ZIP4 ZIP-4 activated in W/Wv mouse stomach 2 mAWMS2 solute carrier family 39 member 4 zrt- and Irt-like protein 4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15\|15 D3

mRNA and Protein(s)

mRNA	Protein	Name
NM_028064.2	NP_082340.1	zinc transporter ZIP4 precursor
XM_006521427.2	XP_006521490.1	zinc transporter ZIP4 isoform X1
NM_028064.3	NP_082340.1	zinc transporter ZIP4 precursor
XM_006521427.1	XP_006521490.1	zinc transporter ZIP4 isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SLC39A4	XP_005628372.1
Homo sapiens (human)	SLC39A4	NP_570901.2
Pan troglodytes (chimpanzee)	SLC39A4	XP_001157597.3
	SLC39A4	XP_001098635.2
Bos taurus (cattle)	SLC39A4	NP_001039532.1
Rattus norvegicus (Norway rat)	Slc39a4	NP_001071137.1
Mus musculus (house mouse)	Slc39a4	NP_082340.1

Gene Ontology
Bibliography

Related articles in PubMed

Requirement of zinc transporter ZIP10 for epidermal development: Implication of the ZIP10-p63 axis in epithelial homeostasis.
Bin BH, Bhin J, Takaishi M, Toyoshima KE, Kawamata S, Ito K, Hara T, Watanabe T, Iri? T, Takagishi T, Lee SH, Jung HS, Rho S, Seo J, Choi DH, Hwang D, Koseki H, Ohara O, Sano S, Tsuji T, Mishima K, Fukada T
Proceedings of the National Academy of Sciences of the United States of America114(46)12243-12248(2017 Nov)

Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse.
Yu C, Ji SY, Dang YJ, Sha QQ, Yuan YF, Zhou JJ, Yan LY, Qiao J, Tang F, Fan HY
Cell research26(3)275-87(2016 Mar)

Zip4 mediated zinc influx stimulates insulin secretion in pancreatic beta cells.
Hardy AB, Prentice KJ, Froese S, Liu Y, Andrews GK, Wheeler MB
PloS one10(3)e0119136(2015)

Clioquinol synergistically augments rescue by zinc supplementation in a mouse model of acrodermatitis enteropathica.
Geiser J, De Lisle RC, Finkelstein D, Adlard PA, Bush AI, Andrews GK
PloS one8(8)e72543(2013)

A mouse model of acrodermatitis enteropathica: loss of intestine zinc transporter ZIP4 (Slc39a4) disrupts the stem cell niche and intestine integrity.
Geiser J, Venken KJ, De Lisle RC, Andrews GK
PLoS genetics8(6)e1002766(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

While Zip4 was not found to be essential for proper glucose homeostasis and insulin secretion in vivo in mice, this study found that Zip4 mediates increases in cytoplasmic and granular zinc pools and stimulates glucose dependent insulin secretion in-vitro
Title: Zip4 mediated zinc influx stimulates insulin secretion in pancreatic beta cells.

These studies strongly suggest that wasting and lethality in acrodermatitis enteropathica patients reflects the loss-of-function of the intestine zinc transporter ZIP4, which leads to abnormal Paneth cell gene expression
Title: A mouse model of acrodermatitis enteropathica: loss of intestine zinc transporter ZIP4 (Slc39a4) disrupts the stem cell niche and intestine integrity.

Cell migration assays revealed that RNAi knockdown of Zip4 in Hepa cells depressed in vitro migration whereas forced over-expression in Hepa cells and MCF-7 cells enhanced in vitro migration
Title: Zip4 (Slc39a4) expression is activated in hepatocellular carcinomas and functions to repress apoptosis, enhance cell cycle and increase migration.

ZIP4 physically interacts with tPA, correlating with an increased intracellular zinc influx and lysosomal sequestration after excitotoxin stimulation. Changes in prosurvival signals support the idea that this sequestration results in neuroprotection.
Title: Tissue plasminogen activator alters intracellular sequestration of zinc through interaction with the transporter ZIP4.

KLF4 is induced during zinc restriction and is a transcription factor involved in adaptive regulation of the zinc transporter ZIP4
Title: Kr?ppel-like factor 4 regulates adaptive expression of the zinc transporter Zip4 in mouse small intestine.

The following Slc39a4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc39a4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu05060	NM_028064.3 Latest version!	Mus musculus solute carrier family 39 (zinc transporter), member 4 (Slc39a4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
OMu51608	XM_006521427.2 Latest version!	Mus musculus solute carrier family 39 (zinc transporter), member 4 (Slc39a4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OMu05060	NM_028064.2	Mus musculus solute carrier family 39 (zinc transporter), member 4 (Slc39a4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
OMu51608	XM_006521427.1	Mus musculus solute carrier family 39 (zinc transporter), member 4 (Slc39a4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc39a4 ( XM_006521427.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006521490.1 Mus musculus solute carrier family 39 (zinc transporter), member 4 (Slc39a4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu51608
Clone ID Related Accession (Same CDS sequence)	XM_006521427.2 , XM_006521427.1
Accession Version	XM_006521427.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1698bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	zinc transporter ZIP4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTCCCAA AGTCGGTCAC ACAGGGACTT GTGTTGGCTC TGCTGGTGGG CACAGTGGCA 
GTGGCCCGGC CCAGGAACCT GCTCAGCCTG CTCGCCTTGG GCCAGGGTGC TCTGGATCGC 
CTGGAACTGG ACGGCCTGTT AAATACGCTG GTGGCCCGTG TGCACTGCAC CGACGGGCCG 
TGTGAAAAGA CCTGTGTAGA TCTTCCCCAA CTGCTGGAGG AGGCTGAGGC AGCAGGGGTT 
TCCAAAAGCG CCGGCCTGGT CTTGACTGCC TTGCTGGATC ATGTCATTAA TGGGTCCTGC 
TTCCAAGGCC TGCCTAGCCC TCAGTACTTT GTGGACTTTG TGTTCAGGCT ACACAGTAGT 
GACCCTCCCA ATATCACGCT GCATGAACTG GAGAATTTGA TGCATCACCT TGGGGTGGGT 
GGAGAGGACC ACAGTGACCA TGATGACCAC GGTGATCATG CTGACCACAG TCATCCGGAC 
AGGAAAGCCA GCCACCAAGA CTCTGAGCTC CATACTCCCC ACAACAGCAA CTCTAGTGTA 
TGGGACACGC TGTGCCTGAG TGCCAAAGAT ATAATGGCTG TGTATGGGCT ATCTGAAGAG 
GCTGGGGTGA GCCCTCAGGC CTGGGCCCAA CTGACCCCTG CCTTGGTCCA GCAGCAGCTA 
AGTGGAGCCT GCAGCCCCTA CCCCACTATC CGTATTCAGG ACCAGCTCAG TCAAACAGAG 
AGGTATCTCT ATGGCTCGCT GGCCACCCTG CTCATCTGCC TCTGTGCTGT GTTCGGTCTT 
CTGCTGCTGA CCTGTGCCAA ATGCAGCACA GCCACCCACT ACATCATGCA GACCTTCCTA 
AGCTTGGCTG TGGGCGCACT TACCGGCGAT GCTCTTCTGC ACCTGATACC CAAGGTGCTG 
GGACTGCACA CACATGGTGG AGAGGGTCAC ACCCATGAGG AGGAGGTGGG CGTTGGTGGG 
CAGGCCACCT GGCGCCTGCT GGCTGTACTT GGAGGCTTCT ACATCTTCTT CCTGTTTGAG 
AGCTTCTTCA ACCTCTTGTT GCCCAGGGAC CAGGATTCTG AGAAAGATGG GCCTTGTAGC 
CATGGTGGGC ACAGCCATGG AATATCTCTG CAGCTGGCAC CAAGCAATCT CCGACAGTCC 
AAACAGACCC ATGAAAGCTC TCGTTCAGAC TTGGTGGCAG AGGAGACCCC GGAACTACTG 
AACCCAGAGA CCCGGCGACT GAGAGCAGAG CTGAGACTGT TGCCCTATCT GATCACACTG 
GGCGACGCGG TACACAACTT CGCTGACGGG CTCGCTGTGG GCGCCGCCTT CTCATCCTCG 
TGGAAGACTG GGCTGGCCAC TTCATTGGCG GTGTTCTGTC ATGAGCTGCC CCATGAACTC 
GGGGACTTCG CTGCTCTGCT GCATGCCGGG CTGAGTGTGA AGCGTGCGCT TTTGCTGAAT 
CTGGCCTCAG CGCTCACAGC ATTCGCAGGC CTCTACGTGG CTCTAGCAGT CGGAGTAGGC 
GAGGAGGGCG AGGCTTGGAT TCTGGCGGTA GCAACCGGCC TCTTCCTTTA CGTGGCGCTT 
TGTGACATGC TCCCAGCCAT GATGAATGTG CGCGACCAGC GGCCCTGGCT TCTTTTCCTG 
CTCCACAACG TGGGTCTGCT GGGCGGCTGG ACCGTCCTGC TGCTGCTGTC ATTGTACGAA 
GACAACATCA CCTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006521490.1
CDS	619..2316
Translation	MLPKSVTQGLVLALLVGTVAVARPRNLLSLLALGQGALDRLELDGLLNTLVARVHCTDGPCEKTCVDLPQLLEEAEAAGVSKSAGLVLTALLDHVINGSCFQGLPSPQYFVDFVFRLHSSDPPNITLHELENLMHHLGVGGEDHSDHDDHGDHADHSHPDRKASHQDSELHTPHNSNSSVWDTLCLSAKDIMAVYGLSEEAGVSPQAWAQLTPALVQQQLSGACSPYPTIRIQDQLSQTERYLYGSLATLLICLCAVFGLLLLTCAKCSTATHYIMQTFLSLAVGALTGDALLHLIPKVLGLHTHGGEGHTHEEEVGVGGQATWRLLAVLGGFYIFFLFESFFNLLLPRDQDSEKDGPCSHGGHSHGISLQLAPSNLRQSKQTHESSRSDLVAEETPELLNPETRRLRAELRLLPYLITLGDAVHNFADGLAVGAAFSSSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVKRALLLNLASALTAFAGLYVALAVGVGEEGEAWILAVATGLFLYVALCDMLPAMMNVRDQRPWLLFLLHNVGLLGGWTVLLLLSLYEDNITF

Target ORF information:

RefSeq Version	XM_006521427.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier family 39 (zinc transporter), member 4 (Slc39a4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006521427.1

ORF Insert Sequence:

ATGCTCCCAA AGTCGGTCAC ACAGGGACTT GTGTTGGCTC TGCTGGTGGG CACAGTGGCA 
GTGGCCCGGC CCAGGAACCT GCTCAGCCTG CTCGCCTTGG GCCAGGGTGC TCTGGATCGC 
CTGGAACTGG ACGGCCTGTT AAATACGCTG GTGGCCCGTG TGCACTGCAC CGACGGGCCG 
TGTGAAAAGA CCTGTGTAGA TCTTCCCCAA CTGCTGGAGG AGGCTGAGGC AGCAGGGGTT 
TCCAAAAGCG CCGGCCTGGT CTTGACTGCC TTGCTGGATC ATGTCATTAA TGGGTCCTGC 
TTCCAAGGCC TGCCTAGCCC TCAGTACTTT GTGGACTTTG TGTTCAGGCT ACACAGTAGT 
GACCCTCCCA ATATCACGCT GCATGAACTG GAGAATTTGA TGCATCACCT TGGGGTGGGT 
GGAGAGGACC ACAGTGACCA TGATGACCAC GGTGATCATG CTGACCACAG TCATCCGGAC 
AGGAAAGCCA GCCACCAAGA CTCTGAGCTC CATACTCCCC ACAACAGCAA CTCTAGTGTA 
TGGGACACGC TGTGCCTGAG TGCCAAAGAT ATAATGGCTG TGTATGGGCT ATCTGAAGAG 
GCTGGGGTGA GCCCTCAGGC CTGGGCCCAA CTGACCCCTG CCTTGGTCCA GCAGCAGCTA 
AGTGGAGCCT GCAGCCCCTA CCCCACTATC CGTATTCAGG ACCAGCTCAG TCAAACAGAG 
AGGTATCTCT ATGGCTCGCT GGCCACCCTG CTCATCTGCC TCTGTGCTGT GTTCGGTCTT 
CTGCTGCTGA CCTGTGCCAA ATGCAGCACA GCCACCCACT ACATCATGCA GACCTTCCTA 
AGCTTGGCTG TGGGCGCACT TACCGGCGAT GCTCTTCTGC ACCTGATACC CAAGGTGCTG 
GGACTGCACA CACATGGTGG AGAGGGTCAC ACCCATGAGG AGGAGGTGGG CGTTGGTGGG 
CAGGCCACCT GGCGCCTGCT GGCTGTACTT GGAGGCTTCT ACATCTTCTT CCTGTTTGAG 
AGCTTCTTCA ACCTCTTGTT GCCCAGGGAC CAGGATTCTG AGAAAGATGG GCCTTGTAGC 
CATGGTGGGC ACAGCCATGG AATATCTCTG CAGCTGGCAC CAAGCAATCT CCGACAGTCC 
AAACAGACCC ATGAAAGCTC TCGTTCAGAC TTGGTGGCAG AGGAGACCCC GGAACTACTG 
AACCCAGAGA CCCGGCGACT GAGAGCAGAG CTGAGACTGT TGCCCTATCT GATCACACTG 
GGCGACGCGG TACACAACTT CGCTGACGGG CTCGCTGTGG GCGCCGCCTT CTCATCCTCG 
TGGAAGACTG GGCTGGCCAC TTCATTGGCG GTGTTCTGTC ATGAGCTGCC CCATGAACTC 
GGGGACTTCG CTGCTCTGCT GCATGCCGGG CTGAGTGTGA AGCGTGCGCT TTTGCTGAAT 
CTGGCCTCAG CGCTCACAGC ATTCGCAGGC CTCTACGTGG CTCTAGCAGT CGGAGTAGGC 
GAGGAGGGCG AGGCTTGGAT TCTGGCGGTA GCAACCGGCC TCTTCCTTTA CGTGGCGCTT 
TGTGACATGC TCCCAGCCAT GATGAATGTG CGCGACCAGC GGCCCTGGCT TCTTTTCCTG 
CTCCACAACG TGGGTCTGCT GGGCGGCTGG ACCGTCCTGC TGCTGCTGTC ATTGTACGAA 
GACAACATCA CCTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc39a4 ( NM_028064.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_082340.1 Mus musculus solute carrier family 39 (zinc transporter), member 4 (Slc39a4), mRNA.

Price & Availability↑

CloneID	OMu05060
Clone ID Related Accession (Same CDS sequence)	NM_028064.2 , NM_028064.3
Accession Version	NM_028064.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1983bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-05-12
Organism	Mus musculus(house mouse)
Product	zinc transporter ZIP4 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC023498.1. On Jan 15, 2003 this sequence version replaced NM_028064.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC023498.1, AK005535.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380 [ECO:0000348] ##Evidence-Data-END##

ATGCTCCCAA AGTCGGTCAC ACAGGGACTT GTGTTGGCTC TGCTGGTGGG CACAGTGGCA 
GTGGCCCGGC CCAGGAACCT GCTCAGCCTG CTCGCCTTGG GCCAGGGTGC TCTGGATCGC 
CTGGAACTGG ACGGCCTGTT AAATACGCTG GTGGCCCGTG TGCACTGCAC CGACGGGCCG 
TGTGAAAAGT GTCTGTCTGT GGAGAATGTC TTGGCTCTAG GCAAACCTGA CAAGCCACAG 
CCTGCCCCAG AATCAGTCCT GGAGTCCAGA CACATTATTT ACCTTAGTGC TGCTGCTGCC 
CTCTACCTTA ACAACCCAGA GAAAACATGC AAGGACATCC AAGCTGGCCT CTTGGCCTCC 
CATGTGGACG ATTACCTGGC CACACTGGAG AGTCCAGAGG CCATGACCCT GGGTCTGAGC 
CAGCTACTGC AGAAGATTGA GGCCCATGCT GCCAGCCAAC CCACCGGGGA GAAGACCTGT 
GTAGATCTTC CCCAACTGCT GGAGGAGGCT GAGGCAGCAG GGGTTTCCAA AAGCGCCGGC 
CTGGTCTTGA CTGCCTTGCT GGATCATGTC ATTAATGGGT CCTGCTTCCA AGGCCTGCCT 
AGCCCTCAGT ACTTTGTGGA CTTTGTGTTC AGGCTACACA GTAGTGACCC TCCCAATATC 
ACGCTGCATG AACTGGAGAA TTTGATGCAT CACCTTGGGG TGGGTGGAGA GGACCACAGT 
GACCATGATG ACCACGGTGA TCATGCTGAC CACAGTCATC CGGACAGGAA AGCCAGCCAC 
CAAGACTCTG AGCTCCATAC TCCCCACAAC AGCAACTCTA GTGTATGGGA CACGCTGTGC 
CTGAGTGCCA AAGATATAAT GGCTGTGTAT GGGCTATCTG AAGAGGCTGG GGTGAGCCCT 
CAGGCCTGGG CCCAACTGAC CCCTGCCTTG GTCCAGCAGC AGCTAAGTGG AGCCTGCAGC 
CCCTACCCCA CTATCCGTAT TCAGGACCAG CTCAGTCAAA CAGAGAGGTA TCTCTATGGC 
TCGCTGGCCA CCCTGCTCAT CTGCCTCTGT GCTGTGTTCG GTCTTCTGCT GCTGACCTGT 
GCCAAATGCA GCACAGCCAC CCACTACATC ATGCAGACCT TCCTAAGCTT GGCTGTGGGC 
GCACTTACCG GCGATGCTCT TCTGCACCTG ATACCCAAGG TGCTGGGACT GCACACACAT 
GGTGGAGAGG GTCACACCCA TGAGGAGGAG GTGGGCGTTG GTGGGCAGGC CACCTGGCGC 
CTGCTGGCTG TACTTGGAGG CTTCTACATC TTCTTCCTGT TTGAGAGCTT CTTCAACCTC 
TTGTTGCCCA GGGACCAGGA TTCTGAGAAA GATGGGCCTT GTAGCCATGG TGGGCACAGC 
CATGGAATAT CTCTGCAGCT GGCACCAAGC AATCTCCGAC AGTCCAAACA GACCCATGAA 
AGCTCTCGTT CAGACTTGGT GGCAGAGGAG ACCCCGGAAC TACTGAACCC AGAGACCCGG 
CGACTGAGAG CAGAGCTGAG ACTGTTGCCC TATCTGATCA CACTGGGCGA CGCGGTACAC 
AACTTCGCTG ACGGGCTCGC TGTGGGCGCC GCCTTCTCAT CCTCGTGGAA GACTGGGCTG 
GCCACTTCAT TGGCGGTGTT CTGTCATGAG CTGCCCCATG AACTCGGGGA CTTCGCTGCT 
CTGCTGCATG CCGGGCTGAG TGTGAAGCGT GCGCTTTTGC TGAATCTGGC CTCAGCGCTC 
ACAGCATTCG CAGGCCTCTA CGTGGCTCTA GCAGTCGGAG TAGGCGAGGA GGGCGAGGCT 
TGGATTCTGG CGGTAGCAAC CGGCCTCTTC CTTTACGTGG CGCTTTGTGA CATGCTCCCA 
GCCATGATGA ATGTGCGCGA CCAGCGGCCC TGGCTTCTTT TCCTGCTCCA CAACGTGGGT 
CTGCTGGGCG GCTGGACCGT CCTGCTGCTG CTGTCATTGT ACGAAGACAA CATCACCTTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_082340.1
CDS	92..2074
Translation	MLPKSVTQGLVLALLVGTVAVARPRNLLSLLALGQGALDRLELDGLLNTLVARVHCTDGPCEKCLSVENVLALGKPDKPQPAPESVLESRHIIYLSAAAALYLNNPEKTCKDIQAGLLASHVDDYLATLESPEAMTLGLSQLLQKIEAHAASQPTGEKTCVDLPQLLEEAEAAGVSKSAGLVLTALLDHVINGSCFQGLPSPQYFVDFVFRLHSSDPPNITLHELENLMHHLGVGGEDHSDHDDHGDHADHSHPDRKASHQDSELHTPHNSNSSVWDTLCLSAKDIMAVYGLSEEAGVSPQAWAQLTPALVQQQLSGACSPYPTIRIQDQLSQTERYLYGSLATLLICLCAVFGLLLLTCAKCSTATHYIMQTFLSLAVGALTGDALLHLIPKVLGLHTHGGEGHTHEEEVGVGGQATWRLLAVLGGFYIFFLFESFFNLLLPRDQDSEKDGPCSHGGHSHGISLQLAPSNLRQSKQTHESSRSDLVAEETPELLNPETRRLRAELRLLPYLITLGDAVHNFADGLAVGAAFSSSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVKRALLLNLASALTAFAGLYVALAVGVGEEGEAWILAVATGLFLYVALCDMLPAMMNVRDQRPWLLFLLHNVGLLGGWTVLLLLSLYEDNITF

Target ORF information:

RefSeq Version	NM_028064.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier family 39 (zinc transporter), member 4 (Slc39a4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_028064.2

ORF Insert Sequence:

ATGCTCCCAA AGTCGGTCAC ACAGGGACTT GTGTTGGCTC TGCTGGTGGG CACAGTGGCA 
GTGGCCCGGC CCAGGAACCT GCTCAGCCTG CTCGCCTTGG GCCAGGGTGC TCTGGATCGC 
CTGGAACTGG ACGGCCTGTT AAATACGCTG GTGGCCCGTG TGCACTGCAC CGACGGGCCG 
TGTGAAAAGT GTCTGTCTGT GGAGAATGTC TTGGCTCTAG GCAAACCTGA CAAGCCACAG 
CCTGCCCCAG AATCAGTCCT GGAGTCCAGA CACATTATTT ACCTTAGTGC TGCTGCTGCC 
CTCTACCTTA ACAACCCAGA GAAAACATGC AAGGACATCC AAGCTGGCCT CTTGGCCTCC 
CATGTGGACG ATTACCTGGC CACACTGGAG AGTCCAGAGG CCATGACCCT GGGTCTGAGC 
CAGCTACTGC AGAAGATTGA GGCCCATGCT GCCAGCCAAC CCACCGGGGA GAAGACCTGT 
GTAGATCTTC CCCAACTGCT GGAGGAGGCT GAGGCAGCAG GGGTTTCCAA AAGCGCCGGC 
CTGGTCTTGA CTGCCTTGCT GGATCATGTC ATTAATGGGT CCTGCTTCCA AGGCCTGCCT 
AGCCCTCAGT ACTTTGTGGA CTTTGTGTTC AGGCTACACA GTAGTGACCC TCCCAATATC 
ACGCTGCATG AACTGGAGAA TTTGATGCAT CACCTTGGGG TGGGTGGAGA GGACCACAGT 
GACCATGATG ACCACGGTGA TCATGCTGAC CACAGTCATC CGGACAGGAA AGCCAGCCAC 
CAAGACTCTG AGCTCCATAC TCCCCACAAC AGCAACTCTA GTGTATGGGA CACGCTGTGC 
CTGAGTGCCA AAGATATAAT GGCTGTGTAT GGGCTATCTG AAGAGGCTGG GGTGAGCCCT 
CAGGCCTGGG CCCAACTGAC CCCTGCCTTG GTCCAGCAGC AGCTAAGTGG AGCCTGCAGC 
CCCTACCCCA CTATCCGTAT TCAGGACCAG CTCAGTCAAA CAGAGAGGTA TCTCTATGGC 
TCGCTGGCCA CCCTGCTCAT CTGCCTCTGT GCTGTGTTCG GTCTTCTGCT GCTGACCTGT 
GCCAAATGCA GCACAGCCAC CCACTACATC ATGCAGACCT TCCTAAGCTT GGCTGTGGGC 
GCACTTACCG GCGATGCTCT TCTGCACCTG ATACCCAAGG TGCTGGGACT GCACACACAT 
GGTGGAGAGG GTCACACCCA TGAGGAGGAG GTGGGCGTTG GTGGGCAGGC CACCTGGCGC 
CTGCTGGCTG TACTTGGAGG CTTCTACATC TTCTTCCTGT TTGAGAGCTT CTTCAACCTC 
TTGTTGCCCA GGGACCAGGA TTCTGAGAAA GATGGGCCTT GTAGCCATGG TGGGCACAGC 
CATGGAATAT CTCTGCAGCT GGCACCAAGC AATCTCCGAC AGTCCAAACA GACCCATGAA 
AGCTCTCGTT CAGACTTGGT GGCAGAGGAG ACCCCGGAAC TACTGAACCC AGAGACCCGG 
CGACTGAGAG CAGAGCTGAG ACTGTTGCCC TATCTGATCA CACTGGGCGA CGCGGTACAC 
AACTTCGCTG ACGGGCTCGC TGTGGGCGCC GCCTTCTCAT CCTCGTGGAA GACTGGGCTG 
GCCACTTCAT TGGCGGTGTT CTGTCATGAG CTGCCCCATG AACTCGGGGA CTTCGCTGCT 
CTGCTGCATG CCGGGCTGAG TGTGAAGCGT GCGCTTTTGC TGAATCTGGC CTCAGCGCTC 
ACAGCATTCG CAGGCCTCTA CGTGGCTCTA GCAGTCGGAG TAGGCGAGGA GGGCGAGGCT 
TGGATTCTGG CGGTAGCAAC CGGCCTCTTC CTTTACGTGG CGCTTTGTGA CATGCTCCCA 
GCCATGATGA ATGTGCGCGA CCAGCGGCCC TGGCTTCTTT TCCTGCTCCA CAACGTGGGT 
CTGCTGGGCG GCTGGACCGT CCTGCTGCTG CTGTCATTGT ACGAAGACAA CATCACCTTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc39a4 ( NM_028064.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_082340.1 Mus musculus solute carrier family 39 (zinc transporter), member 4 (Slc39a4), mRNA.

Price & Availability↑

CloneID	OMu05060
Clone ID Related Accession (Same CDS sequence)	NM_028064.2 , NM_028064.3
Accession Version	NM_028064.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1983bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-27
Organism	Mus musculus(house mouse)
Product	zinc transporter ZIP4 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC157566.6. On Jul 12, 2018 this sequence version replaced NM_028064.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC023498.1, AK005535.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTCCCAA AGTCGGTCAC ACAGGGACTT GTGTTGGCTC TGCTGGTGGG CACAGTGGCA 
GTGGCCCGGC CCAGGAACCT GCTCAGCCTG CTCGCCTTGG GCCAGGGTGC TCTGGATCGC 
CTGGAACTGG ACGGCCTGTT AAATACGCTG GTGGCCCGTG TGCACTGCAC CGACGGGCCG 
TGTGAAAAGT GTCTGTCTGT GGAGAATGTC TTGGCTCTAG GCAAACCTGA CAAGCCACAG 
CCTGCCCCAG AATCAGTCCT GGAGTCCAGA CACATTATTT ACCTTAGTGC TGCTGCTGCC 
CTCTACCTTA ACAACCCAGA GAAAACATGC AAGGACATCC AAGCTGGCCT CTTGGCCTCC 
CATGTGGACG ATTACCTGGC CACACTGGAG AGTCCAGAGG CCATGACCCT GGGTCTGAGC 
CAGCTACTGC AGAAGATTGA GGCCCATGCT GCCAGCCAAC CCACCGGGGA GAAGACCTGT 
GTAGATCTTC CCCAACTGCT GGAGGAGGCT GAGGCAGCAG GGGTTTCCAA AAGCGCCGGC 
CTGGTCTTGA CTGCCTTGCT GGATCATGTC ATTAATGGGT CCTGCTTCCA AGGCCTGCCT 
AGCCCTCAGT ACTTTGTGGA CTTTGTGTTC AGGCTACACA GTAGTGACCC TCCCAATATC 
ACGCTGCATG AACTGGAGAA TTTGATGCAT CACCTTGGGG TGGGTGGAGA GGACCACAGT 
GACCATGATG ACCACGGTGA TCATGCTGAC CACAGTCATC CGGACAGGAA AGCCAGCCAC 
CAAGACTCTG AGCTCCATAC TCCCCACAAC AGCAACTCTA GTGTATGGGA CACGCTGTGC 
CTGAGTGCCA AAGATATAAT GGCTGTGTAT GGGCTATCTG AAGAGGCTGG GGTGAGCCCT 
CAGGCCTGGG CCCAACTGAC CCCTGCCTTG GTCCAGCAGC AGCTAAGTGG AGCCTGCAGC 
CCCTACCCCA CTATCCGTAT TCAGGACCAG CTCAGTCAAA CAGAGAGGTA TCTCTATGGC 
TCGCTGGCCA CCCTGCTCAT CTGCCTCTGT GCTGTGTTCG GTCTTCTGCT GCTGACCTGT 
GCCAAATGCA GCACAGCCAC CCACTACATC ATGCAGACCT TCCTAAGCTT GGCTGTGGGC 
GCACTTACCG GCGATGCTCT TCTGCACCTG ATACCCAAGG TGCTGGGACT GCACACACAT 
GGTGGAGAGG GTCACACCCA TGAGGAGGAG GTGGGCGTTG GTGGGCAGGC CACCTGGCGC 
CTGCTGGCTG TACTTGGAGG CTTCTACATC TTCTTCCTGT TTGAGAGCTT CTTCAACCTC 
TTGTTGCCCA GGGACCAGGA TTCTGAGAAA GATGGGCCTT GTAGCCATGG TGGGCACAGC 
CATGGAATAT CTCTGCAGCT GGCACCAAGC AATCTCCGAC AGTCCAAACA GACCCATGAA 
AGCTCTCGTT CAGACTTGGT GGCAGAGGAG ACCCCGGAAC TACTGAACCC AGAGACCCGG 
CGACTGAGAG CAGAGCTGAG ACTGTTGCCC TATCTGATCA CACTGGGCGA CGCGGTACAC 
AACTTCGCTG ACGGGCTCGC TGTGGGCGCC GCCTTCTCAT CCTCGTGGAA GACTGGGCTG 
GCCACTTCAT TGGCGGTGTT CTGTCATGAG CTGCCCCATG AACTCGGGGA CTTCGCTGCT 
CTGCTGCATG CCGGGCTGAG TGTGAAGCGT GCGCTTTTGC TGAATCTGGC CTCAGCGCTC 
ACAGCATTCG CAGGCCTCTA CGTGGCTCTA GCAGTCGGAG TAGGCGAGGA GGGCGAGGCT 
TGGATTCTGG CGGTAGCAAC CGGCCTCTTC CTTTACGTGG CGCTTTGTGA CATGCTCCCA 
GCCATGATGA ATGTGCGCGA CCAGCGGCCC TGGCTTCTTT TCCTGCTCCA CAACGTGGGT 
CTGCTGGGCG GCTGGACCGT CCTGCTGCTG CTGTCATTGT ACGAAGACAA CATCACCTTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_082340.1
CDS	110..2092
Translation	MLPKSVTQGLVLALLVGTVAVARPRNLLSLLALGQGALDRLELDGLLNTLVARVHCTDGPCEKCLSVENVLALGKPDKPQPAPESVLESRHIIYLSAAAALYLNNPEKTCKDIQAGLLASHVDDYLATLESPEAMTLGLSQLLQKIEAHAASQPTGEKTCVDLPQLLEEAEAAGVSKSAGLVLTALLDHVINGSCFQGLPSPQYFVDFVFRLHSSDPPNITLHELENLMHHLGVGGEDHSDHDDHGDHADHSHPDRKASHQDSELHTPHNSNSSVWDTLCLSAKDIMAVYGLSEEAGVSPQAWAQLTPALVQQQLSGACSPYPTIRIQDQLSQTERYLYGSLATLLICLCAVFGLLLLTCAKCSTATHYIMQTFLSLAVGALTGDALLHLIPKVLGLHTHGGEGHTHEEEVGVGGQATWRLLAVLGGFYIFFLFESFFNLLLPRDQDSEKDGPCSHGGHSHGISLQLAPSNLRQSKQTHESSRSDLVAEETPELLNPETRRLRAELRLLPYLITLGDAVHNFADGLAVGAAFSSSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVKRALLLNLASALTAFAGLYVALAVGVGEEGEAWILAVATGLFLYVALCDMLPAMMNVRDQRPWLLFLLHNVGLLGGWTVLLLLSLYEDNITF

Target ORF information:

RefSeq Version	NM_028064.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier family 39 (zinc transporter), member 4 (Slc39a4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_028064.3

ORF Insert Sequence:

ATGCTCCCAA AGTCGGTCAC ACAGGGACTT GTGTTGGCTC TGCTGGTGGG CACAGTGGCA 
GTGGCCCGGC CCAGGAACCT GCTCAGCCTG CTCGCCTTGG GCCAGGGTGC TCTGGATCGC 
CTGGAACTGG ACGGCCTGTT AAATACGCTG GTGGCCCGTG TGCACTGCAC CGACGGGCCG 
TGTGAAAAGT GTCTGTCTGT GGAGAATGTC TTGGCTCTAG GCAAACCTGA CAAGCCACAG 
CCTGCCCCAG AATCAGTCCT GGAGTCCAGA CACATTATTT ACCTTAGTGC TGCTGCTGCC 
CTCTACCTTA ACAACCCAGA GAAAACATGC AAGGACATCC AAGCTGGCCT CTTGGCCTCC 
CATGTGGACG ATTACCTGGC CACACTGGAG AGTCCAGAGG CCATGACCCT GGGTCTGAGC 
CAGCTACTGC AGAAGATTGA GGCCCATGCT GCCAGCCAAC CCACCGGGGA GAAGACCTGT 
GTAGATCTTC CCCAACTGCT GGAGGAGGCT GAGGCAGCAG GGGTTTCCAA AAGCGCCGGC 
CTGGTCTTGA CTGCCTTGCT GGATCATGTC ATTAATGGGT CCTGCTTCCA AGGCCTGCCT 
AGCCCTCAGT ACTTTGTGGA CTTTGTGTTC AGGCTACACA GTAGTGACCC TCCCAATATC 
ACGCTGCATG AACTGGAGAA TTTGATGCAT CACCTTGGGG TGGGTGGAGA GGACCACAGT 
GACCATGATG ACCACGGTGA TCATGCTGAC CACAGTCATC CGGACAGGAA AGCCAGCCAC 
CAAGACTCTG AGCTCCATAC TCCCCACAAC AGCAACTCTA GTGTATGGGA CACGCTGTGC 
CTGAGTGCCA AAGATATAAT GGCTGTGTAT GGGCTATCTG AAGAGGCTGG GGTGAGCCCT 
CAGGCCTGGG CCCAACTGAC CCCTGCCTTG GTCCAGCAGC AGCTAAGTGG AGCCTGCAGC 
CCCTACCCCA CTATCCGTAT TCAGGACCAG CTCAGTCAAA CAGAGAGGTA TCTCTATGGC 
TCGCTGGCCA CCCTGCTCAT CTGCCTCTGT GCTGTGTTCG GTCTTCTGCT GCTGACCTGT 
GCCAAATGCA GCACAGCCAC CCACTACATC ATGCAGACCT TCCTAAGCTT GGCTGTGGGC 
GCACTTACCG GCGATGCTCT TCTGCACCTG ATACCCAAGG TGCTGGGACT GCACACACAT 
GGTGGAGAGG GTCACACCCA TGAGGAGGAG GTGGGCGTTG GTGGGCAGGC CACCTGGCGC 
CTGCTGGCTG TACTTGGAGG CTTCTACATC TTCTTCCTGT TTGAGAGCTT CTTCAACCTC 
TTGTTGCCCA GGGACCAGGA TTCTGAGAAA GATGGGCCTT GTAGCCATGG TGGGCACAGC 
CATGGAATAT CTCTGCAGCT GGCACCAAGC AATCTCCGAC AGTCCAAACA GACCCATGAA 
AGCTCTCGTT CAGACTTGGT GGCAGAGGAG ACCCCGGAAC TACTGAACCC AGAGACCCGG 
CGACTGAGAG CAGAGCTGAG ACTGTTGCCC TATCTGATCA CACTGGGCGA CGCGGTACAC 
AACTTCGCTG ACGGGCTCGC TGTGGGCGCC GCCTTCTCAT CCTCGTGGAA GACTGGGCTG 
GCCACTTCAT TGGCGGTGTT CTGTCATGAG CTGCCCCATG AACTCGGGGA CTTCGCTGCT 
CTGCTGCATG CCGGGCTGAG TGTGAAGCGT GCGCTTTTGC TGAATCTGGC CTCAGCGCTC 
ACAGCATTCG CAGGCCTCTA CGTGGCTCTA GCAGTCGGAG TAGGCGAGGA GGGCGAGGCT 
TGGATTCTGG CGGTAGCAAC CGGCCTCTTC CTTTACGTGG CGCTTTGTGA CATGCTCCCA 
GCCATGATGA ATGTGCGCGA CCAGCGGCCC TGGCTTCTTT TCCTGCTCCA CAACGTGGGT 
CTGCTGGGCG GCTGGACCGT CCTGCTGCTG CTGTCATTGT ACGAAGACAA CATCACCTTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc39a4 ( XM_006521427.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006521490.1 Mus musculus solute carrier family 39 (zinc transporter), member 4 (Slc39a4), transcript variant X1, mRNA.

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CloneID	OMu51608
Clone ID Related Accession (Same CDS sequence)	XM_006521427.2 , XM_006521427.1
Accession Version	XM_006521427.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1698bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	zinc transporter ZIP4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006521427.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTCCCAA AGTCGGTCAC ACAGGGACTT GTGTTGGCTC TGCTGGTGGG CACAGTGGCA 
GTGGCCCGGC CCAGGAACCT GCTCAGCCTG CTCGCCTTGG GCCAGGGTGC TCTGGATCGC 
CTGGAACTGG ACGGCCTGTT AAATACGCTG GTGGCCCGTG TGCACTGCAC CGACGGGCCG 
TGTGAAAAGA CCTGTGTAGA TCTTCCCCAA CTGCTGGAGG AGGCTGAGGC AGCAGGGGTT 
TCCAAAAGCG CCGGCCTGGT CTTGACTGCC TTGCTGGATC ATGTCATTAA TGGGTCCTGC 
TTCCAAGGCC TGCCTAGCCC TCAGTACTTT GTGGACTTTG TGTTCAGGCT ACACAGTAGT 
GACCCTCCCA ATATCACGCT GCATGAACTG GAGAATTTGA TGCATCACCT TGGGGTGGGT 
GGAGAGGACC ACAGTGACCA TGATGACCAC GGTGATCATG CTGACCACAG TCATCCGGAC 
AGGAAAGCCA GCCACCAAGA CTCTGAGCTC CATACTCCCC ACAACAGCAA CTCTAGTGTA 
TGGGACACGC TGTGCCTGAG TGCCAAAGAT ATAATGGCTG TGTATGGGCT ATCTGAAGAG 
GCTGGGGTGA GCCCTCAGGC CTGGGCCCAA CTGACCCCTG CCTTGGTCCA GCAGCAGCTA 
AGTGGAGCCT GCAGCCCCTA CCCCACTATC CGTATTCAGG ACCAGCTCAG TCAAACAGAG 
AGGTATCTCT ATGGCTCGCT GGCCACCCTG CTCATCTGCC TCTGTGCTGT GTTCGGTCTT 
CTGCTGCTGA CCTGTGCCAA ATGCAGCACA GCCACCCACT ACATCATGCA GACCTTCCTA 
AGCTTGGCTG TGGGCGCACT TACCGGCGAT GCTCTTCTGC ACCTGATACC CAAGGTGCTG 
GGACTGCACA CACATGGTGG AGAGGGTCAC ACCCATGAGG AGGAGGTGGG CGTTGGTGGG 
CAGGCCACCT GGCGCCTGCT GGCTGTACTT GGAGGCTTCT ACATCTTCTT CCTGTTTGAG 
AGCTTCTTCA ACCTCTTGTT GCCCAGGGAC CAGGATTCTG AGAAAGATGG GCCTTGTAGC 
CATGGTGGGC ACAGCCATGG AATATCTCTG CAGCTGGCAC CAAGCAATCT CCGACAGTCC 
AAACAGACCC ATGAAAGCTC TCGTTCAGAC TTGGTGGCAG AGGAGACCCC GGAACTACTG 
AACCCAGAGA CCCGGCGACT GAGAGCAGAG CTGAGACTGT TGCCCTATCT GATCACACTG 
GGCGACGCGG TACACAACTT CGCTGACGGG CTCGCTGTGG GCGCCGCCTT CTCATCCTCG 
TGGAAGACTG GGCTGGCCAC TTCATTGGCG GTGTTCTGTC ATGAGCTGCC CCATGAACTC 
GGGGACTTCG CTGCTCTGCT GCATGCCGGG CTGAGTGTGA AGCGTGCGCT TTTGCTGAAT 
CTGGCCTCAG CGCTCACAGC ATTCGCAGGC CTCTACGTGG CTCTAGCAGT CGGAGTAGGC 
GAGGAGGGCG AGGCTTGGAT TCTGGCGGTA GCAACCGGCC TCTTCCTTTA CGTGGCGCTT 
TGTGACATGC TCCCAGCCAT GATGAATGTG CGCGACCAGC GGCCCTGGCT TCTTTTCCTG 
CTCCACAACG TGGGTCTGCT GGGCGGCTGG ACCGTCCTGC TGCTGCTGTC ATTGTACGAA 
GACAACATCA CCTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006521490.1
CDS	1746..3443
Translation	MLPKSVTQGLVLALLVGTVAVARPRNLLSLLALGQGALDRLELDGLLNTLVARVHCTDGPCEKTCVDLPQLLEEAEAAGVSKSAGLVLTALLDHVINGSCFQGLPSPQYFVDFVFRLHSSDPPNITLHELENLMHHLGVGGEDHSDHDDHGDHADHSHPDRKASHQDSELHTPHNSNSSVWDTLCLSAKDIMAVYGLSEEAGVSPQAWAQLTPALVQQQLSGACSPYPTIRIQDQLSQTERYLYGSLATLLICLCAVFGLLLLTCAKCSTATHYIMQTFLSLAVGALTGDALLHLIPKVLGLHTHGGEGHTHEEEVGVGGQATWRLLAVLGGFYIFFLFESFFNLLLPRDQDSEKDGPCSHGGHSHGISLQLAPSNLRQSKQTHESSRSDLVAEETPELLNPETRRLRAELRLLPYLITLGDAVHNFADGLAVGAAFSSSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVKRALLLNLASALTAFAGLYVALAVGVGEEGEAWILAVATGLFLYVALCDMLPAMMNVRDQRPWLLFLLHNVGLLGGWTVLLLLSLYEDNITF

Target ORF information:

RefSeq Version	XM_006521427.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier family 39 (zinc transporter), member 4 (Slc39a4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006521427.2

ORF Insert Sequence:

ATGCTCCCAA AGTCGGTCAC ACAGGGACTT GTGTTGGCTC TGCTGGTGGG CACAGTGGCA 
GTGGCCCGGC CCAGGAACCT GCTCAGCCTG CTCGCCTTGG GCCAGGGTGC TCTGGATCGC 
CTGGAACTGG ACGGCCTGTT AAATACGCTG GTGGCCCGTG TGCACTGCAC CGACGGGCCG 
TGTGAAAAGA CCTGTGTAGA TCTTCCCCAA CTGCTGGAGG AGGCTGAGGC AGCAGGGGTT 
TCCAAAAGCG CCGGCCTGGT CTTGACTGCC TTGCTGGATC ATGTCATTAA TGGGTCCTGC 
TTCCAAGGCC TGCCTAGCCC TCAGTACTTT GTGGACTTTG TGTTCAGGCT ACACAGTAGT 
GACCCTCCCA ATATCACGCT GCATGAACTG GAGAATTTGA TGCATCACCT TGGGGTGGGT 
GGAGAGGACC ACAGTGACCA TGATGACCAC GGTGATCATG CTGACCACAG TCATCCGGAC 
AGGAAAGCCA GCCACCAAGA CTCTGAGCTC CATACTCCCC ACAACAGCAA CTCTAGTGTA 
TGGGACACGC TGTGCCTGAG TGCCAAAGAT ATAATGGCTG TGTATGGGCT ATCTGAAGAG 
GCTGGGGTGA GCCCTCAGGC CTGGGCCCAA CTGACCCCTG CCTTGGTCCA GCAGCAGCTA 
AGTGGAGCCT GCAGCCCCTA CCCCACTATC CGTATTCAGG ACCAGCTCAG TCAAACAGAG 
AGGTATCTCT ATGGCTCGCT GGCCACCCTG CTCATCTGCC TCTGTGCTGT GTTCGGTCTT 
CTGCTGCTGA CCTGTGCCAA ATGCAGCACA GCCACCCACT ACATCATGCA GACCTTCCTA 
AGCTTGGCTG TGGGCGCACT TACCGGCGAT GCTCTTCTGC ACCTGATACC CAAGGTGCTG 
GGACTGCACA CACATGGTGG AGAGGGTCAC ACCCATGAGG AGGAGGTGGG CGTTGGTGGG 
CAGGCCACCT GGCGCCTGCT GGCTGTACTT GGAGGCTTCT ACATCTTCTT CCTGTTTGAG 
AGCTTCTTCA ACCTCTTGTT GCCCAGGGAC CAGGATTCTG AGAAAGATGG GCCTTGTAGC 
CATGGTGGGC ACAGCCATGG AATATCTCTG CAGCTGGCAC CAAGCAATCT CCGACAGTCC 
AAACAGACCC ATGAAAGCTC TCGTTCAGAC TTGGTGGCAG AGGAGACCCC GGAACTACTG 
AACCCAGAGA CCCGGCGACT GAGAGCAGAG CTGAGACTGT TGCCCTATCT GATCACACTG 
GGCGACGCGG TACACAACTT CGCTGACGGG CTCGCTGTGG GCGCCGCCTT CTCATCCTCG 
TGGAAGACTG GGCTGGCCAC TTCATTGGCG GTGTTCTGTC ATGAGCTGCC CCATGAACTC 
GGGGACTTCG CTGCTCTGCT GCATGCCGGG CTGAGTGTGA AGCGTGCGCT TTTGCTGAAT 
CTGGCCTCAG CGCTCACAGC ATTCGCAGGC CTCTACGTGG CTCTAGCAGT CGGAGTAGGC 
GAGGAGGGCG AGGCTTGGAT TCTGGCGGTA GCAACCGGCC TCTTCCTTTA CGTGGCGCTT 
TGTGACATGC TCCCAGCCAT GATGAATGTG CGCGACCAGC GGCCCTGGCT TCTTTTCCTG 
CTCCACAACG TGGGTCTGCT GGGCGGCTGG ACCGTCCTGC TGCTGCTGTC ATTGTACGAA 
GACAACATCA CCTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Requirement of zinc transporter ZIP10 for epidermal development: Implication of the ZIP10-p63 axis in epithelial homeostasis.
Proceedings of the National Academy of Sciences of the United States of America114(46)12243-12248(2017 Nov)
Bin BH,Bhin J,Takaishi M,Toyoshima KE,Kawamata S,Ito K,Hara T,Watanabe T,Iri? T,Takagishi T,Lee SH,Jung HS,Rho S,Seo J,Choi DH,Hwang D,Koseki H,Ohara O,Sano S,Tsuji T,Mishima K,Fukada T

Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse.
Cell research26(3)275-87(2016 Mar)
Yu C,Ji SY,Dang YJ,Sha QQ,Yuan YF,Zhou JJ,Yan LY,Qiao J,Tang F,Fan HY

Zip4 mediated zinc influx stimulates insulin secretion in pancreatic beta cells.
PloS one10(3)e0119136(2015)
Hardy AB,Prentice KJ,Froese S,Liu Y,Andrews GK,Wheeler MB

Clioquinol synergistically augments rescue by zinc supplementation in a mouse model of acrodermatitis enteropathica.
PloS one8(8)e72543(2013)
Geiser J,De Lisle RC,Finkelstein D,Adlard PA,Bush AI,Andrews GK

A mouse model of acrodermatitis enteropathica: loss of intestine zinc transporter ZIP4 (Slc39a4) disrupts the stem cell niche and intestine integrity.
PLoS genetics8(6)e1002766(2012)
Geiser J,Venken KJ,De Lisle RC,Andrews GK

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Slc39a4 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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