Denr cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Denr
Entrez Gene ID	68184
Full Name	density-regulated protein
Synonyms	1500003K04Rik
General protein information	Preferred Names density-regulated protein Names density-regulated protein DRP
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5\|5 F

mRNA and Protein(s)

mRNA	Protein	Name
XM_006530452.3	XP_006530515.1	density-regulated protein isoform X1
XM_011248238.1	XP_011246540.1	density-regulated protein isoform X2
XM_011248238.2	XP_011246540.1	density-regulated protein isoform X2
NM_026603.4	NP_080879.1	density-regulated protein
XM_006530452.2	XP_006530515.1	density-regulated protein isoform X1

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	DENR	NP_001072973.1
Homo sapiens (human)	DENR	NP_003668.2
Caenorhabditis elegans (roundworm)	Y47D3A.21	NP_499450.1
Saccharomyces cerevisiae (baker's yeast)	TMA22	NP_012548.1
Magnaporthe oryzae (rice blast fungus)	MGG_04504	XP_003710951.1
Pan troglodytes (chimpanzee)	DENR	XP_003952390.1
Mus musculus (house mouse)	Denr	NP_080879.1
Kluyveromyces lactis	KLLA0F21934g	XP_456059.1
Neurospora crassa	NCU02984	XP_965370.1
Arabidopsis thaliana (thale cress)	AT5G11900	NP_196751.2
Rattus norvegicus (Norway rat)	LOC687565	NP_001108518.1
Drosophila melanogaster (fruit fly)	CG9099	NP_001259630.1
Schizosaccharomyces pombe (fission yeast)	SPBC16C6.05	NP_596803.1
Oryza sativa (rice)	Os01g0195500	NP_001042291.2
Xenopus tropicalis (tropical clawed frog)	denr	NP_001006814.1
Canis lupus familiaris (dog)	DENR	XP_853345.3
Bos taurus (cattle)	DENR	NP_001039993.1
Danio rerio (zebrafish)	denr	NP_001002697.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006125	XP_316185.3
Eremothecium gossypii	AGOS_ACL112C	NP_983292.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

De Novo Mutations in DENR Disrupt Neuronal Development and Link Congenital Neurological Disorders to Faulty mRNA Translation Re-initiation.
Haas MA, Ngo L, Li SS, Schleich S, Qu Z, Vanyai HK, Cullen HD, Cardona-Alberich A, Gladwyn-Ng IE, Pagnamenta AT, Taylor JC, Stewart H, Kini U, Duncan KE, Teleman AA, Keays DA, Heng JI
Cell reports15(10)2251-2265(2016 06)

An actin-dependent step in mitochondrial fission mediated by the ER-associated formin INF2.
Korobova F, Ramabhadran V, Higgs HN
Science (New York, N.Y.)339(6118)464-7(2013 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Denr influences the migration of murine cerebral cortical neurons in vivo with its binding partner Mcts1.
Title: De Novo Mutations in DENR Disrupt Neuronal Development and Link Congenital Neurological Disorders to Faulty mRNA Translation Re-initiation.

The following Denr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Denr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu02656	NM_026603.4 Latest version!	Mus musculus density-regulated protein (Denr), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu35994	XM_006530452.3 Latest version!	Mus musculus density-regulated protein (Denr), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OMu70230	XM_011248238.2 Latest version!	Mus musculus density-regulated protein (Denr), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu70230	XM_011248238.1	Mus musculus density-regulated protein (Denr), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu35994	XM_006530452.2	Mus musculus density-regulated protein (Denr), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Denr ( NM_026603.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_080879.1 Mus musculus density-regulated protein (Denr), mRNA.

Price & Availability↑

CloneID	OMu02656
Clone ID Related Accession (Same CDS sequence)	NM_026603.4
Accession Version	NM_026603.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 597bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Mus musculus(house mouse)
Product	density-regulated protein
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC122753.11. On Oct 19, 2007 this sequence version replaced NM_026603.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK018762.1, AK135127.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849384 [ECO:0000348] ##Evidence-Data-END##

ATGGCTACTG ACATTTCTGA ATCCAGCGGG GCGGATTGCA AAGGCGATAC GAAGAACAGT 
GCCAAGTTAG ATGCGGATTA CCCTCTTCGA GTCCTTTATT GTGGAGTCTG TTCATTACCA 
ACAGAGTACT GTGAATACAT GCCGGATGTT GCTAAATGTA GACAATGGCT AGAGAAGAAC 
TTTCCAAATG AATTTGCAAA ACTTACTGTA GAAAATTCAC CCAAACAAGA AACTGGAATT 
ACTGAAGGCC AAGGACCAGT AGGGGAAGAG GAGGAGAAGA AAAAACAAAA AAGAGGTGGA 
AGAGGTCAAA TAAAACAGAA GAAGAAGACA GTACCACAGA AGGTCACGAT AGCCAAAATT 
CCCAGAGCAA AGAAGAAATA CGTGACGAGA GTGTGTGGCC TTGCAACTTT TGAAATTGAT 
CTCAAAGAAG CACAAAGATT TTTTGCTCAA AAATTCTCGT GCGGTGCCTC AGTGACAGGG 
GAGGACGAGA TCATCATTCA GGGAGACTTC ACAGATGACA TCATTGACGT CATTCAGGAA 
AAGTGGCCAG AGGTGGATGA CGACAGCATT GAAGACCTTG GAGAAGTGAA GAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_080879.1
CDS	102..698
Translation	MATDISESSGADCKGDTKNSAKLDADYPLRVLYCGVCSLPTEYCEYMPDVAKCRQWLEKNFPNEFAKLTVENSPKQETGITEGQGPVGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK

Target ORF information:

RefSeq Version	NM_026603.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus density-regulated protein (Denr), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_026603.4

ORF Insert Sequence:

ATGGCTACTG ACATTTCTGA ATCCAGCGGG GCGGATTGCA AAGGCGATAC GAAGAACAGT 
GCCAAGTTAG ATGCGGATTA CCCTCTTCGA GTCCTTTATT GTGGAGTCTG TTCATTACCA 
ACAGAGTACT GTGAATACAT GCCGGATGTT GCTAAATGTA GACAATGGCT AGAGAAGAAC 
TTTCCAAATG AATTTGCAAA ACTTACTGTA GAAAATTCAC CCAAACAAGA AACTGGAATT 
ACTGAAGGCC AAGGACCAGT AGGGGAAGAG GAGGAGAAGA AAAAACAAAA AAGAGGTGGA 
AGAGGTCAAA TAAAACAGAA GAAGAAGACA GTACCACAGA AGGTCACGAT AGCCAAAATT 
CCCAGAGCAA AGAAGAAATA CGTGACGAGA GTGTGTGGCC TTGCAACTTT TGAAATTGAT 
CTCAAAGAAG CACAAAGATT TTTTGCTCAA AAATTCTCGT GCGGTGCCTC AGTGACAGGG 
GAGGACGAGA TCATCATTCA GGGAGACTTC ACAGATGACA TCATTGACGT CATTCAGGAA 
AAGTGGCCAG AGGTGGATGA CGACAGCATT GAAGACCTTG GAGAAGTGAA GAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Denr ( XM_011248238.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011246540.1 Mus musculus density-regulated protein (Denr), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu70230
Clone ID Related Accession (Same CDS sequence)	XM_011248238.1 , XM_011248238.2
Accession Version	XM_011248238.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 459bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	density-regulated protein isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGGATG TTGCTAAATG TAGACAATGG CTAGAGAAGA ACTTTCCAAA TGAATTTGCA 
AAACTTACTG TAGAAAATTC ACCCAAACAA GAAACTGGAA TTACTGAAGG CCAAGGACCA 
GTAGGGGAAG AGGAGGAGAA GAAAAAACAA AAAAGAGGTG GAAGAGGTCA AATAAAACAG 
AAGAAGAAGA CAGTACCACA GAAGGTCACG ATAGCCAAAA TTCCCAGAGC AAAGAAGAAA 
TACGTGACGA GAGTGTGTGG CCTTGCAACT TTTGAAATTG ATCTCAAAGA AGCACAAAGA 
TTTTTTGCTC AAAAATTCTC GTGCGGTGCC TCAGTGACAG GGGAGGACGA GATCATCATT 
CAGGGAGACT TCACAGATGA CATCATTGAC GTCATTCAGG AAAAGTGGCC AGAGGTGGAT 
GACGACAGCA TTGAAGACCT TGGAGAAGTG AAGAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011246540.1
CDS	405..863
Translation	MPDVAKCRQWLEKNFPNEFAKLTVENSPKQETGITEGQGPVGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK

Target ORF information:

RefSeq Version	XM_011248238.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus density-regulated protein (Denr), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011248238.1

ORF Insert Sequence:

ATGCCGGATG TTGCTAAATG TAGACAATGG CTAGAGAAGA ACTTTCCAAA TGAATTTGCA 
AAACTTACTG TAGAAAATTC ACCCAAACAA GAAACTGGAA TTACTGAAGG CCAAGGACCA 
GTAGGGGAAG AGGAGGAGAA GAAAAAACAA AAAAGAGGTG GAAGAGGTCA AATAAAACAG 
AAGAAGAAGA CAGTACCACA GAAGGTCACG ATAGCCAAAA TTCCCAGAGC AAAGAAGAAA 
TACGTGACGA GAGTGTGTGG CCTTGCAACT TTTGAAATTG ATCTCAAAGA AGCACAAAGA 
TTTTTTGCTC AAAAATTCTC GTGCGGTGCC TCAGTGACAG GGGAGGACGA GATCATCATT 
CAGGGAGACT TCACAGATGA CATCATTGAC GTCATTCAGG AAAAGTGGCC AGAGGTGGAT 
GACGACAGCA TTGAAGACCT TGGAGAAGTG AAGAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Denr ( XM_006530452.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006530515.1 Mus musculus density-regulated protein (Denr), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu35994
Clone ID Related Accession (Same CDS sequence)	XM_006530452.3 , XM_006530452.2
Accession Version	XM_006530452.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 507bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	density-regulated protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006530452.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGGATTA CCCTCTTCGA GTCCTTTATT GTGGAGTACT GTGAATACAT GCCGGATGTT 
GCTAAATGTA GACAATGGCT AGAGAAGAAC TTTCCAAATG AATTTGCAAA ACTTACTGTA 
GAAAATTCAC CCAAACAAGA AACTGGAATT ACTGAAGGCC AAGGACCAGT AGGGGAAGAG 
GAGGAGAAGA AAAAACAAAA AAGAGGTGGA AGAGGTCAAA TAAAACAGAA GAAGAAGACA 
GTACCACAGA AGGTCACGAT AGCCAAAATT CCCAGAGCAA AGAAGAAATA CGTGACGAGA 
GTGTGTGGCC TTGCAACTTT TGAAATTGAT CTCAAAGAAG CACAAAGATT TTTTGCTCAA 
AAATTCTCGT GCGGTGCCTC AGTGACAGGG GAGGACGAGA TCATCATTCA GGGAGACTTC 
ACAGATGACA TCATTGACGT CATTCAGGAA AAGTGGCCAG AGGTGGATGA CGACAGCATT 
GAAGACCTTG GAGAAGTGAA GAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006530515.1
CDS	131..637
Translation	MRITLFESFIVEYCEYMPDVAKCRQWLEKNFPNEFAKLTVENSPKQETGITEGQGPVGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK

Target ORF information:

RefSeq Version	XM_006530452.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus density-regulated protein (Denr), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006530452.2

ORF Insert Sequence:

ATGCGGATTA CCCTCTTCGA GTCCTTTATT GTGGAGTACT GTGAATACAT GCCGGATGTT 
GCTAAATGTA GACAATGGCT AGAGAAGAAC TTTCCAAATG AATTTGCAAA ACTTACTGTA 
GAAAATTCAC CCAAACAAGA AACTGGAATT ACTGAAGGCC AAGGACCAGT AGGGGAAGAG 
GAGGAGAAGA AAAAACAAAA AAGAGGTGGA AGAGGTCAAA TAAAACAGAA GAAGAAGACA 
GTACCACAGA AGGTCACGAT AGCCAAAATT CCCAGAGCAA AGAAGAAATA CGTGACGAGA 
GTGTGTGGCC TTGCAACTTT TGAAATTGAT CTCAAAGAAG CACAAAGATT TTTTGCTCAA 
AAATTCTCGT GCGGTGCCTC AGTGACAGGG GAGGACGAGA TCATCATTCA GGGAGACTTC 
ACAGATGACA TCATTGACGT CATTCAGGAA AAGTGGCCAG AGGTGGATGA CGACAGCATT 
GAAGACCTTG GAGAAGTGAA GAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Denr ( XM_006530452.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006530515.1 Mus musculus density-regulated protein (Denr), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu35994
Clone ID Related Accession (Same CDS sequence)	XM_006530452.3 , XM_006530452.2
Accession Version	XM_006530452.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 507bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	density-regulated protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006530452.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGGATTA CCCTCTTCGA GTCCTTTATT GTGGAGTACT GTGAATACAT GCCGGATGTT 
GCTAAATGTA GACAATGGCT AGAGAAGAAC TTTCCAAATG AATTTGCAAA ACTTACTGTA 
GAAAATTCAC CCAAACAAGA AACTGGAATT ACTGAAGGCC AAGGACCAGT AGGGGAAGAG 
GAGGAGAAGA AAAAACAAAA AAGAGGTGGA AGAGGTCAAA TAAAACAGAA GAAGAAGACA 
GTACCACAGA AGGTCACGAT AGCCAAAATT CCCAGAGCAA AGAAGAAATA CGTGACGAGA 
GTGTGTGGCC TTGCAACTTT TGAAATTGAT CTCAAAGAAG CACAAAGATT TTTTGCTCAA 
AAATTCTCGT GCGGTGCCTC AGTGACAGGG GAGGACGAGA TCATCATTCA GGGAGACTTC 
ACAGATGACA TCATTGACGT CATTCAGGAA AAGTGGCCAG AGGTGGATGA CGACAGCATT 
GAAGACCTTG GAGAAGTGAA GAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006530515.1
CDS	242..748
Translation	MRITLFESFIVEYCEYMPDVAKCRQWLEKNFPNEFAKLTVENSPKQETGITEGQGPVGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK

Target ORF information:

RefSeq Version	XM_006530452.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus density-regulated protein (Denr), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006530452.3

ORF Insert Sequence:

ATGCGGATTA CCCTCTTCGA GTCCTTTATT GTGGAGTACT GTGAATACAT GCCGGATGTT 
GCTAAATGTA GACAATGGCT AGAGAAGAAC TTTCCAAATG AATTTGCAAA ACTTACTGTA 
GAAAATTCAC CCAAACAAGA AACTGGAATT ACTGAAGGCC AAGGACCAGT AGGGGAAGAG 
GAGGAGAAGA AAAAACAAAA AAGAGGTGGA AGAGGTCAAA TAAAACAGAA GAAGAAGACA 
GTACCACAGA AGGTCACGAT AGCCAAAATT CCCAGAGCAA AGAAGAAATA CGTGACGAGA 
GTGTGTGGCC TTGCAACTTT TGAAATTGAT CTCAAAGAAG CACAAAGATT TTTTGCTCAA 
AAATTCTCGT GCGGTGCCTC AGTGACAGGG GAGGACGAGA TCATCATTCA GGGAGACTTC 
ACAGATGACA TCATTGACGT CATTCAGGAA AAGTGGCCAG AGGTGGATGA CGACAGCATT 
GAAGACCTTG GAGAAGTGAA GAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Denr ( XM_011248238.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011246540.1 Mus musculus density-regulated protein (Denr), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu70230
Clone ID Related Accession (Same CDS sequence)	XM_011248238.1 , XM_011248238.2
Accession Version	XM_011248238.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 459bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	density-regulated protein isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011248238.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGGATG TTGCTAAATG TAGACAATGG CTAGAGAAGA ACTTTCCAAA TGAATTTGCA 
AAACTTACTG TAGAAAATTC ACCCAAACAA GAAACTGGAA TTACTGAAGG CCAAGGACCA 
GTAGGGGAAG AGGAGGAGAA GAAAAAACAA AAAAGAGGTG GAAGAGGTCA AATAAAACAG 
AAGAAGAAGA CAGTACCACA GAAGGTCACG ATAGCCAAAA TTCCCAGAGC AAAGAAGAAA 
TACGTGACGA GAGTGTGTGG CCTTGCAACT TTTGAAATTG ATCTCAAAGA AGCACAAAGA 
TTTTTTGCTC AAAAATTCTC GTGCGGTGCC TCAGTGACAG GGGAGGACGA GATCATCATT 
CAGGGAGACT TCACAGATGA CATCATTGAC GTCATTCAGG AAAAGTGGCC AGAGGTGGAT 
GACGACAGCA TTGAAGACCT TGGAGAAGTG AAGAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011246540.1
CDS	409..867
Translation	MPDVAKCRQWLEKNFPNEFAKLTVENSPKQETGITEGQGPVGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK

Target ORF information:

RefSeq Version	XM_011248238.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus density-regulated protein (Denr), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011248238.2

ORF Insert Sequence:

ATGCCGGATG TTGCTAAATG TAGACAATGG CTAGAGAAGA ACTTTCCAAA TGAATTTGCA 
AAACTTACTG TAGAAAATTC ACCCAAACAA GAAACTGGAA TTACTGAAGG CCAAGGACCA 
GTAGGGGAAG AGGAGGAGAA GAAAAAACAA AAAAGAGGTG GAAGAGGTCA AATAAAACAG 
AAGAAGAAGA CAGTACCACA GAAGGTCACG ATAGCCAAAA TTCCCAGAGC AAAGAAGAAA 
TACGTGACGA GAGTGTGTGG CCTTGCAACT TTTGAAATTG ATCTCAAAGA AGCACAAAGA 
TTTTTTGCTC AAAAATTCTC GTGCGGTGCC TCAGTGACAG GGGAGGACGA GATCATCATT 
CAGGGAGACT TCACAGATGA CATCATTGAC GTCATTCAGG AAAAGTGGCC AGAGGTGGAT 
GACGACAGCA TTGAAGACCT TGGAGAAGTG AAGAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

De Novo Mutations in DENR Disrupt Neuronal Development and Link Congenital Neurological Disorders to Faulty mRNA Translation Re-initiation.
Cell reports15(10)2251-2265(2016 06)
Haas MA,Ngo L,Li SS,Schleich S,Qu Z,Vanyai HK,Cullen HD,Cardona-Alberich A,Gladwyn-Ng IE,Pagnamenta AT,Taylor JC,Stewart H,Kini U,Duncan KE,Teleman AA,Keays DA,Heng JI

An actin-dependent step in mitochondrial fission mediated by the ER-associated formin INF2.
Science (New York, N.Y.)339(6118)464-7(2013 Jan)
Korobova F,Ramabhadran V,Higgs HN

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Denr cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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