Ccdc159 cDNA ORF clone, Mus musculus(house mouse)

The following Ccdc159 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ccdc159 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu09946 NM_001164614.1
Latest version!
Mus musculus coiled-coil domain containing 159 (Ccdc159), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
OMu42360 XM_006510553.3
Latest version!
Mus musculus coiled-coil domain containing 159 (Ccdc159), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
OMu42361 XM_006510554.3
Latest version!
Mus musculus coiled-coil domain containing 159 (Ccdc159), transcript variant X2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
OMu42362 XM_017313526.1
Latest version!
Mus musculus coiled-coil domain containing 159 (Ccdc159), transcript variant X3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $139.30
$199.00
OMu42362 XM_006510555.2
Latest version!
Mus musculus coiled-coil domain containing 159 (Ccdc159), transcript variant X4, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $139.30
$199.00
OMu01353 NM_025977.3
Latest version!
Mus musculus coiled-coil domain containing 159 (Ccdc159), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 5-7 $223.30
$319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

  • Reference Sequences (Refseq)
    CloneID OMu09946
    Clone ID Related Accession (Same CDS sequence) NM_001164614.1
    Accession Version NM_001164614.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1236bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-02-22
    Organism Mus musculus(house mouse)
    Product coiled-coil domain-containing protein 159 isoform 1
    Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK011114.1 and AK042884.1. Transcript Variant: This variant (1) encodes the longer protein (isoform 1). ##Evidence-Data-START## Transcript exon combination :: AK042884.1, BC145014.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGGGAGAGC ATGAACGGGT GGTATGCTGT AGTAGTGACT CTCTTTTGGC TGGCCTATCC 
    CGGGACTCTG ACGACTGTGT TTCTCATCTC TGCACACCTC CGTTACTCGC CATCACATCT
    TGGGCTGCTA AGGAGAGGAG CCAGTACTCA CCACCTCCTG GAGAGCCTGG GCCCTCCTCA
    GACAAGGCTT TGGACTGTAT GACCCACTGG TCCAGGGTTT TGGAGCCTGA GATCGTGAAC
    ACTGCTTCTG AACAAGCAGG GAAGTCTGGG GCCTGGGAGA AGGAGTGGGA CTCAGAACCA
    CAGCCTCATG AGGGTACACC CTGTTCCAGC TCAGACGTGA ACAAGGACCA TTATCATGAC
    CAGGACCTTG TGAAGAGGAA CCACTGTGTA GCCAAGAAGT CCCTGGAGCC CAGCTCAGCC
    AAAGTAAAAG TTAAGAACAC CATGATAATT CCTGACTCTC AGAAGCTCTT GCGATGCGAA
    CTGGAGTCTC TCAGGAGCCA GCTGCAGGCT CAGAGCAAGG CTTTCGAGTT CCTGAATCAC
    TCTGTGACCA TGCTGGAGAA GGAGAGCTGC CTACAGCAGA TCAAGATTCA GCAGCTTGAA
    GAAGTGCTGA GCCCCACGAG CCGCCAAGGA GAGAAGTATG GCCGTAAGTG GAGCACAGAG
    CAGGAGCTGT ATGGGGCCCT GGCTCAAGGC CTGCAGGGGT TGCAGAAGAC ACTGAAGGAA
    GGCGAGGAGC TGCAACGGGC CCGTACCACT CGCTGCCTGC AGCTGTTGGC CCGGGAGATC
    CGGGACAGCA AGAAGTTCCT GTGGGAGGAA CTGGAGCTGG TGCGGGAAGA GGTGACTTTC
    ATCTATCAGA AACTCCAGGA CCAGGAGGAT GAGATCTCAG AGAATCTCCT GAATATCCAG
    AAGATGCAGA AAACTCAGGT GAAGTGCCGC AAGGTTCTTA CCAAGATGAA GCAGCAGGCA
    TACGATTCAT GGCCAGAAGC CGAGGGGGTG CCCACAGAAG GCAACGGTTG CTGTAAGGAT
    GACCTCCAGA AGGAGCTGGG TGACATATGG TCTGCCGTTC ACAGTCTGCA GAGCTCCATT
    GACTGTCTTG CTTTGTCAAT GGGCACCAGA CCCAGGGCCT CCAGCCTCAG AGGCCAGAAA
    GGACACCAGT GCAAGAGCTC TCAGTGCCCC TCCTGGGACT CCGATTCAGA CTGGGAGAGA
    CCTTTCAGCA AGAGTGGATC CTACCCTCCC GCTTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001158086.1
    CDS238..1473
    Translation

    Target ORF information:

    RefSeq Version NM_001164614.1
    Organism Mus musculus(house mouse)
    Definition Mus musculus coiled-coil domain containing 159 (Ccdc159), transcript variant 1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001164614.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGGGAGAGC ATGAACGGGT GGTATGCTGT AGTAGTGACT CTCTTTTGGC TGGCCTATCC 
    CGGGACTCTG ACGACTGTGT TTCTCATCTC TGCACACCTC CGTTACTCGC CATCACATCT
    TGGGCTGCTA AGGAGAGGAG CCAGTACTCA CCACCTCCTG GAGAGCCTGG GCCCTCCTCA
    GACAAGGCTT TGGACTGTAT GACCCACTGG TCCAGGGTTT TGGAGCCTGA GATCGTGAAC
    ACTGCTTCTG AACAAGCAGG GAAGTCTGGG GCCTGGGAGA AGGAGTGGGA CTCAGAACCA
    CAGCCTCATG AGGGTACACC CTGTTCCAGC TCAGACGTGA ACAAGGACCA TTATCATGAC
    CAGGACCTTG TGAAGAGGAA CCACTGTGTA GCCAAGAAGT CCCTGGAGCC CAGCTCAGCC
    AAAGTAAAAG TTAAGAACAC CATGATAATT CCTGACTCTC AGAAGCTCTT GCGATGCGAA
    CTGGAGTCTC TCAGGAGCCA GCTGCAGGCT CAGAGCAAGG CTTTCGAGTT CCTGAATCAC
    TCTGTGACCA TGCTGGAGAA GGAGAGCTGC CTACAGCAGA TCAAGATTCA GCAGCTTGAA
    GAAGTGCTGA GCCCCACGAG CCGCCAAGGA GAGAAGTATG GCCGTAAGTG GAGCACAGAG
    CAGGAGCTGT ATGGGGCCCT GGCTCAAGGC CTGCAGGGGT TGCAGAAGAC ACTGAAGGAA
    GGCGAGGAGC TGCAACGGGC CCGTACCACT CGCTGCCTGC AGCTGTTGGC CCGGGAGATC
    CGGGACAGCA AGAAGTTCCT GTGGGAGGAA CTGGAGCTGG TGCGGGAAGA GGTGACTTTC
    ATCTATCAGA AACTCCAGGA CCAGGAGGAT GAGATCTCAG AGAATCTCCT GAATATCCAG
    AAGATGCAGA AAACTCAGGT GAAGTGCCGC AAGGTTCTTA CCAAGATGAA GCAGCAGGCA
    TACGATTCAT GGCCAGAAGC CGAGGGGGTG CCCACAGAAG GCAACGGTTG CTGTAAGGAT
    GACCTCCAGA AGGAGCTGGG TGACATATGG TCTGCCGTTC ACAGTCTGCA GAGCTCCATT
    GACTGTCTTG CTTTGTCAAT GGGCACCAGA CCCAGGGCCT CCAGCCTCAG AGGCCAGAAA
    GGACACCAGT GCAAGAGCTC TCAGTGCCCC TCCTGGGACT CCGATTCAGA CTGGGAGAGA
    CCTTTCAGCA AGAGTGGATC CTACCCTCCC GCTTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OMu42360
    Clone ID Related Accession (Same CDS sequence) XM_006510553.3
    Accession Version XM_006510553.3 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1284bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2016-06-21
    Organism Mus musculus(house mouse)
    Product coiled-coil domain-containing protein 159 isoform X1
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006510553.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGGGAGAGC ATGAACGGGT GGTATGCTGT AGTAGTGACT CTCTTTTGGC TGGCCTATCC 
    CGGGACTCTG ACGACTGTGT TTCTCATCTC TGCACACCTC CGTTACTCGC CATCACATCT
    TGGGCTGCTA AGGAGAGGAG CCAGTACTCA CCACCTCCTG GAGAGCCTGG GCCCTCCTCA
    GACAAGGCTT TGGACTGTAT GACCCACTGG TCCAGGGTTT TGGAGCCTGA GATCGTGAAC
    ACTGCTTCTG AACAAGCAGG GAAGTCTGGG GCCTGGGAGA AGGAGTGGGA CTCAGAACCA
    CAGCCTCATG AGGGTACACC CTGTTCCAGC TCAGACGTGA ACAAGGACCA TTATCATGAC
    CAGGACCTTG TGAAGAGGAA CCACTGTGTA GCCAAGAAGT CCCTGGAGCC CAGCTCAGCC
    AAAGTAAAAG TTAAGAACAC CATGATAATT CCTGACTCTC AGAAGCTCTT GCGATGCGAA
    CTGGAGTCTC TCAGGAGCCA GCTGCAGGCT CAGAGCAAGG CTTTCGAGTT CCTGAATCAC
    TCTGTGACCA TGCTGGAGAA GGAGAGCTGC CTACAGCAGA TCAAGATTCA GCAGCTTGAA
    GAAGTGCTGA GCCCCACGAG CCGCCAAGGA GAGAAGTATG GCCGTAAGTG GAGCACAGAG
    CAGGAGCTGT ATGGGGCCCT GGCTCAAGGC CTGCAGGGGT TGCAGAAGAC ACTGAAGGAA
    GGCGAGGAGC TGCAACGGGC CCGTACCACT CGCTGCCTGC AGCTGTTGGC CCGGGAGATC
    CGGGACAGCA AGAAGTTCCT GTGGGAGGAA CTGGAGCTGG TGCGGGAAGA GGTGACTTTC
    ATCTATCAGA AACTCCAGGA CCAGGAGGAT GAGATCTCAG AGAATCTCCT GAATATCCAG
    AAGATGCAGA AAACTCAGGT GAAGTGCCGC AAGGTTCTTA CCAAGATGAA GCAGCAGGCA
    TACGATTCAT GGCCAGAAGC CGAGGGGGTG CCCACAGAAG GCAACGGTTG CTGTAAGGAT
    GACCTCCAGA AGGAGCTGGG TGACATATGG TCTGCCGTTC ACAGTCTGCA GAGCTCCATT
    GACTGTCTTG CTTTGTCAAT GGGCACCAGA CCCAGGGCCT CCAGCCTCAG AGGCCAGAAA
    GGACACCAGT GCAAGAGCTC TCAGTGCCCC TCCTGGGACT CCGATTCAGA CTGGGAGAGA
    CCTTTCAGCA AGAGTGGATC CTACCCTCCC GGTACAGACC CTACTCAGCC CCTCTCCATC
    CCTTACCATC TGGCCCACTT GTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_006510616.1
    CDS162..1445
    Translation

    Target ORF information:

    RefSeq Version XM_006510553.3
    Organism Mus musculus(house mouse)
    Definition Mus musculus coiled-coil domain containing 159 (Ccdc159), transcript variant X1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_006510553.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGGGAGAGC ATGAACGGGT GGTATGCTGT AGTAGTGACT CTCTTTTGGC TGGCCTATCC 
    CGGGACTCTG ACGACTGTGT TTCTCATCTC TGCACACCTC CGTTACTCGC CATCACATCT
    TGGGCTGCTA AGGAGAGGAG CCAGTACTCA CCACCTCCTG GAGAGCCTGG GCCCTCCTCA
    GACAAGGCTT TGGACTGTAT GACCCACTGG TCCAGGGTTT TGGAGCCTGA GATCGTGAAC
    ACTGCTTCTG AACAAGCAGG GAAGTCTGGG GCCTGGGAGA AGGAGTGGGA CTCAGAACCA
    CAGCCTCATG AGGGTACACC CTGTTCCAGC TCAGACGTGA ACAAGGACCA TTATCATGAC
    CAGGACCTTG TGAAGAGGAA CCACTGTGTA GCCAAGAAGT CCCTGGAGCC CAGCTCAGCC
    AAAGTAAAAG TTAAGAACAC CATGATAATT CCTGACTCTC AGAAGCTCTT GCGATGCGAA
    CTGGAGTCTC TCAGGAGCCA GCTGCAGGCT CAGAGCAAGG CTTTCGAGTT CCTGAATCAC
    TCTGTGACCA TGCTGGAGAA GGAGAGCTGC CTACAGCAGA TCAAGATTCA GCAGCTTGAA
    GAAGTGCTGA GCCCCACGAG CCGCCAAGGA GAGAAGTATG GCCGTAAGTG GAGCACAGAG
    CAGGAGCTGT ATGGGGCCCT GGCTCAAGGC CTGCAGGGGT TGCAGAAGAC ACTGAAGGAA
    GGCGAGGAGC TGCAACGGGC CCGTACCACT CGCTGCCTGC AGCTGTTGGC CCGGGAGATC
    CGGGACAGCA AGAAGTTCCT GTGGGAGGAA CTGGAGCTGG TGCGGGAAGA GGTGACTTTC
    ATCTATCAGA AACTCCAGGA CCAGGAGGAT GAGATCTCAG AGAATCTCCT GAATATCCAG
    AAGATGCAGA AAACTCAGGT GAAGTGCCGC AAGGTTCTTA CCAAGATGAA GCAGCAGGCA
    TACGATTCAT GGCCAGAAGC CGAGGGGGTG CCCACAGAAG GCAACGGTTG CTGTAAGGAT
    GACCTCCAGA AGGAGCTGGG TGACATATGG TCTGCCGTTC ACAGTCTGCA GAGCTCCATT
    GACTGTCTTG CTTTGTCAAT GGGCACCAGA CCCAGGGCCT CCAGCCTCAG AGGCCAGAAA
    GGACACCAGT GCAAGAGCTC TCAGTGCCCC TCCTGGGACT CCGATTCAGA CTGGGAGAGA
    CCTTTCAGCA AGAGTGGATC CTACCCTCCC GGTACAGACC CTACTCAGCC CCTCTCCATC
    CCTTACCATC TGGCCCACTT GTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OMu42361
    Clone ID Related Accession (Same CDS sequence) XM_006510554.3
    Accession Version XM_006510554.3 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1260bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2016-06-21
    Organism Mus musculus(house mouse)
    Product coiled-coil domain-containing protein 159 isoform X2
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006510554.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGAACGGGT GTGACTCTCT TTTGGCTGGC CTATCCCGGG ACTCTGACGA CTGTGTTTCT 
    CATCTCTGCA CACCTCCGTT ACTCGCCATC ACATCTTGGG CTGCTAAGGA GAGGAGCCAG
    TACTCACCAC CTCCTGGAGA GCCTGGGCCC TCCTCAGACA AGGCTTTGGA CTGTATGACC
    CACTGGTCCA GGGTTTTGGA GCCTGAGATC GTGAACACTG CTTCTGAACA AGCAGGGAAG
    TCTGGGGCCT GGGAGAAGGA GTGGGACTCA GAACCACAGC CTCATGAGGG TACACCCTGT
    TCCAGCTCAG ACGTGAACAA GGACCATTAT CATGACCAGG ACCTTGTGAA GAGGAACCAC
    TGTGTAGCCA AGAAGTCCCT GGAGCCCAGC TCAGCCAAAG TAAAAGTTAA GAACACCATG
    ATAATTCCTG ACTCTCAGAA GCTCTTGCGA TGCGAACTGG AGTCTCTCAG GAGCCAGCTG
    CAGGCTCAGA GCAAGGCTTT CGAGTTCCTG AATCACTCTG TGACCATGCT GGAGAAGGAG
    AGCTGCCTAC AGCAGATCAA GATTCAGCAG CTTGAAGAAG TGCTGAGCCC CACGAGCCGC
    CAAGGAGAGA AGTATGGCCG TAAGTGGAGC ACAGAGCAGG AGCTGTATGG GGCCCTGGCT
    CAAGGCCTGC AGGGGTTGCA GAAGACACTG AAGGAAGGCG AGGAGCTGCA ACGGGCCCGT
    ACCACTCGCT GCCTGCAGCT GTTGGCCCGG GAGATCCGGG ACAGCAAGAA GTTCCTGTGG
    GAGGAACTGG AGCTGGTGCG GGAAGAGGTG ACTTTCATCT ATCAGAAACT CCAGGACCAG
    GAGGATGAGA TCTCAGAGAA TCTCCTGAAT ATCCAGAAGA TGCAGAAAAC TCAGGTGAAG
    TGCCGCAAGG TTCTTACCAA GATGAAGCAG CAGGCATACG ATTCATGGCC AGAAGCCGAG
    GGGGTGCCCA CAGAAGGCAA CGGTTGCTGT AAGGATGACC TCCAGAAGGA GCTGGGTGAC
    ATATGGTCTG CCGTTCACAG TCTGCAGAGC TCCATTGACT GTCTTGCTTT GTCAATGGGC
    ACCAGACCCA GGGCCTCCAG CCTCAGAGGC CAGAAAGGAC ACCAGTGCAA GAGCTCTCAG
    TGCCCCTCCT GGGACTCCGA TTCAGACTGG GAGAGACCTT TCAGCAAGAG TGGATCCTAC
    CCTCCCGGTA CAGACCCTAC TCAGCCCCTC TCCATCCCTT ACCATCTGGC CCACTTGTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_006510617.1
    CDS171..1430
    Translation

    Target ORF information:

    RefSeq Version XM_006510554.3
    Organism Mus musculus(house mouse)
    Definition Mus musculus coiled-coil domain containing 159 (Ccdc159), transcript variant X2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_006510554.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGAACGGGT GTGACTCTCT TTTGGCTGGC CTATCCCGGG ACTCTGACGA CTGTGTTTCT 
    CATCTCTGCA CACCTCCGTT ACTCGCCATC ACATCTTGGG CTGCTAAGGA GAGGAGCCAG
    TACTCACCAC CTCCTGGAGA GCCTGGGCCC TCCTCAGACA AGGCTTTGGA CTGTATGACC
    CACTGGTCCA GGGTTTTGGA GCCTGAGATC GTGAACACTG CTTCTGAACA AGCAGGGAAG
    TCTGGGGCCT GGGAGAAGGA GTGGGACTCA GAACCACAGC CTCATGAGGG TACACCCTGT
    TCCAGCTCAG ACGTGAACAA GGACCATTAT CATGACCAGG ACCTTGTGAA GAGGAACCAC
    TGTGTAGCCA AGAAGTCCCT GGAGCCCAGC TCAGCCAAAG TAAAAGTTAA GAACACCATG
    ATAATTCCTG ACTCTCAGAA GCTCTTGCGA TGCGAACTGG AGTCTCTCAG GAGCCAGCTG
    CAGGCTCAGA GCAAGGCTTT CGAGTTCCTG AATCACTCTG TGACCATGCT GGAGAAGGAG
    AGCTGCCTAC AGCAGATCAA GATTCAGCAG CTTGAAGAAG TGCTGAGCCC CACGAGCCGC
    CAAGGAGAGA AGTATGGCCG TAAGTGGAGC ACAGAGCAGG AGCTGTATGG GGCCCTGGCT
    CAAGGCCTGC AGGGGTTGCA GAAGACACTG AAGGAAGGCG AGGAGCTGCA ACGGGCCCGT
    ACCACTCGCT GCCTGCAGCT GTTGGCCCGG GAGATCCGGG ACAGCAAGAA GTTCCTGTGG
    GAGGAACTGG AGCTGGTGCG GGAAGAGGTG ACTTTCATCT ATCAGAAACT CCAGGACCAG
    GAGGATGAGA TCTCAGAGAA TCTCCTGAAT ATCCAGAAGA TGCAGAAAAC TCAGGTGAAG
    TGCCGCAAGG TTCTTACCAA GATGAAGCAG CAGGCATACG ATTCATGGCC AGAAGCCGAG
    GGGGTGCCCA CAGAAGGCAA CGGTTGCTGT AAGGATGACC TCCAGAAGGA GCTGGGTGAC
    ATATGGTCTG CCGTTCACAG TCTGCAGAGC TCCATTGACT GTCTTGCTTT GTCAATGGGC
    ACCAGACCCA GGGCCTCCAG CCTCAGAGGC CAGAAAGGAC ACCAGTGCAA GAGCTCTCAG
    TGCCCCTCCT GGGACTCCGA TTCAGACTGG GAGAGACCTT TCAGCAAGAG TGGATCCTAC
    CCTCCCGGTA CAGACCCTAC TCAGCCCCTC TCCATCCCTT ACCATCTGGC CCACTTGTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OMu42362
    Clone ID Related Accession (Same CDS sequence) XM_006510555.2 , XM_017313526.1
    Accession Version XM_006510555.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 843bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2016-06-21
    Organism Mus musculus(house mouse)
    Product coiled-coil domain-containing protein 159 isoform X3
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006510555.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGATAATTC CTGACTCTCA GAAGCTCTTG CGATGCGAAC TGGAGTCTCT CAGGAGCCAG 
    CTGCAGGCTC AGAGCAAGGC TTTCGAGTTC CTGAATCACT CTGTGACCAT GCTGGAGAAG
    GAGAGCTGCC TACAGCAGAT CAAGATTCAG CAGCTTGAAG AAGTGCTGAG CCCCACGAGC
    CGCCAAGGAG AGAAGTATGG CCGTAAGTGG AGCACAGAGC AGGAGCTGTA TGGGGCCCTG
    GCTCAAGGCC TGCAGGGGTT GCAGAAGACA CTGAAGGAAG GCGAGGAGCT GCAACGGGCC
    CGTACCACTC GCTGCCTGCA GCTGTTGGCC CGGGAGATCC GGGACAGCAA GAAGTTCCTG
    TGGGAGGAAC TGGAGCTGGT GCGGGAAGAG GTGACTTTCA TCTATCAGAA ACTCCAGGAC
    CAGGAGGATG AGATCTCAGA GAATCTCCTG AATATCCAGA AGATGCAGAA AACTCAGGTG
    AAGTGCCGCA AGGTTCTTAC CAAGATGAAG CAGCAGGCAT ACGATTCATG GCCAGAAGCC
    GAGGGGGTGC CCACAGAAGG CAACGGTTGC TGTAAGGATG ACCTCCAGAA GGAGCTGGGT
    GACATATGGT CTGCCGTTCA CAGTCTGCAG AGCTCCATTG ACTGTCTTGC TTTGTCAATG
    GGCACCAGAC CCAGGGCCTC CAGCCTCAGA GGCCAGAAAG GACACCAGTG CAAGAGCTCT
    CAGTGCCCCT CCTGGGACTC CGATTCAGAC TGGGAGAGAC CTTTCAGCAA GAGTGGATCC
    TACCCTCCCG GTACAGACCC TACTCAGCCC CTCTCCATCC CTTACCATCT GGCCCACTTG
    TGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_006510618.1
    CDS99..941
    Translation

    Target ORF information:

    RefSeq Version XM_006510555.2
    Organism Mus musculus(house mouse)
    Definition Mus musculus coiled-coil domain containing 159 (Ccdc159), transcript variant X4, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_006510555.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGATAATTC CTGACTCTCA GAAGCTCTTG CGATGCGAAC TGGAGTCTCT CAGGAGCCAG 
    CTGCAGGCTC AGAGCAAGGC TTTCGAGTTC CTGAATCACT CTGTGACCAT GCTGGAGAAG
    GAGAGCTGCC TACAGCAGAT CAAGATTCAG CAGCTTGAAG AAGTGCTGAG CCCCACGAGC
    CGCCAAGGAG AGAAGTATGG CCGTAAGTGG AGCACAGAGC AGGAGCTGTA TGGGGCCCTG
    GCTCAAGGCC TGCAGGGGTT GCAGAAGACA CTGAAGGAAG GCGAGGAGCT GCAACGGGCC
    CGTACCACTC GCTGCCTGCA GCTGTTGGCC CGGGAGATCC GGGACAGCAA GAAGTTCCTG
    TGGGAGGAAC TGGAGCTGGT GCGGGAAGAG GTGACTTTCA TCTATCAGAA ACTCCAGGAC
    CAGGAGGATG AGATCTCAGA GAATCTCCTG AATATCCAGA AGATGCAGAA AACTCAGGTG
    AAGTGCCGCA AGGTTCTTAC CAAGATGAAG CAGCAGGCAT ACGATTCATG GCCAGAAGCC
    GAGGGGGTGC CCACAGAAGG CAACGGTTGC TGTAAGGATG ACCTCCAGAA GGAGCTGGGT
    GACATATGGT CTGCCGTTCA CAGTCTGCAG AGCTCCATTG ACTGTCTTGC TTTGTCAATG
    GGCACCAGAC CCAGGGCCTC CAGCCTCAGA GGCCAGAAAG GACACCAGTG CAAGAGCTCT
    CAGTGCCCCT CCTGGGACTC CGATTCAGAC TGGGAGAGAC CTTTCAGCAA GAGTGGATCC
    TACCCTCCCG GTACAGACCC TACTCAGCCC CTCTCCATCC CTTACCATCT GGCCCACTTG
    TGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OMu42362
    Clone ID Related Accession (Same CDS sequence) XM_006510555.2 , XM_017313526.1
    Accession Version XM_017313526.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 843bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2016-06-21
    Organism Mus musculus(house mouse)
    Product coiled-coil domain-containing protein 159 isoform X3
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGATAATTC CTGACTCTCA GAAGCTCTTG CGATGCGAAC TGGAGTCTCT CAGGAGCCAG 
    CTGCAGGCTC AGAGCAAGGC TTTCGAGTTC CTGAATCACT CTGTGACCAT GCTGGAGAAG
    GAGAGCTGCC TACAGCAGAT CAAGATTCAG CAGCTTGAAG AAGTGCTGAG CCCCACGAGC
    CGCCAAGGAG AGAAGTATGG CCGTAAGTGG AGCACAGAGC AGGAGCTGTA TGGGGCCCTG
    GCTCAAGGCC TGCAGGGGTT GCAGAAGACA CTGAAGGAAG GCGAGGAGCT GCAACGGGCC
    CGTACCACTC GCTGCCTGCA GCTGTTGGCC CGGGAGATCC GGGACAGCAA GAAGTTCCTG
    TGGGAGGAAC TGGAGCTGGT GCGGGAAGAG GTGACTTTCA TCTATCAGAA ACTCCAGGAC
    CAGGAGGATG AGATCTCAGA GAATCTCCTG AATATCCAGA AGATGCAGAA AACTCAGGTG
    AAGTGCCGCA AGGTTCTTAC CAAGATGAAG CAGCAGGCAT ACGATTCATG GCCAGAAGCC
    GAGGGGGTGC CCACAGAAGG CAACGGTTGC TGTAAGGATG ACCTCCAGAA GGAGCTGGGT
    GACATATGGT CTGCCGTTCA CAGTCTGCAG AGCTCCATTG ACTGTCTTGC TTTGTCAATG
    GGCACCAGAC CCAGGGCCTC CAGCCTCAGA GGCCAGAAAG GACACCAGTG CAAGAGCTCT
    CAGTGCCCCT CCTGGGACTC CGATTCAGAC TGGGAGAGAC CTTTCAGCAA GAGTGGATCC
    TACCCTCCCG GTACAGACCC TACTCAGCCC CTCTCCATCC CTTACCATCT GGCCCACTTG
    TGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_017169015.1
    CDS306..1148
    Translation

    Target ORF information:

    RefSeq Version XM_017313526.1
    Organism Mus musculus(house mouse)
    Definition Mus musculus coiled-coil domain containing 159 (Ccdc159), transcript variant X3, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_017313526.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGATAATTC CTGACTCTCA GAAGCTCTTG CGATGCGAAC TGGAGTCTCT CAGGAGCCAG 
    CTGCAGGCTC AGAGCAAGGC TTTCGAGTTC CTGAATCACT CTGTGACCAT GCTGGAGAAG
    GAGAGCTGCC TACAGCAGAT CAAGATTCAG CAGCTTGAAG AAGTGCTGAG CCCCACGAGC
    CGCCAAGGAG AGAAGTATGG CCGTAAGTGG AGCACAGAGC AGGAGCTGTA TGGGGCCCTG
    GCTCAAGGCC TGCAGGGGTT GCAGAAGACA CTGAAGGAAG GCGAGGAGCT GCAACGGGCC
    CGTACCACTC GCTGCCTGCA GCTGTTGGCC CGGGAGATCC GGGACAGCAA GAAGTTCCTG
    TGGGAGGAAC TGGAGCTGGT GCGGGAAGAG GTGACTTTCA TCTATCAGAA ACTCCAGGAC
    CAGGAGGATG AGATCTCAGA GAATCTCCTG AATATCCAGA AGATGCAGAA AACTCAGGTG
    AAGTGCCGCA AGGTTCTTAC CAAGATGAAG CAGCAGGCAT ACGATTCATG GCCAGAAGCC
    GAGGGGGTGC CCACAGAAGG CAACGGTTGC TGTAAGGATG ACCTCCAGAA GGAGCTGGGT
    GACATATGGT CTGCCGTTCA CAGTCTGCAG AGCTCCATTG ACTGTCTTGC TTTGTCAATG
    GGCACCAGAC CCAGGGCCTC CAGCCTCAGA GGCCAGAAAG GACACCAGTG CAAGAGCTCT
    CAGTGCCCCT CCTGGGACTC CGATTCAGAC TGGGAGAGAC CTTTCAGCAA GAGTGGATCC
    TACCCTCCCG GTACAGACCC TACTCAGCCC CTCTCCATCC CTTACCATCT GGCCCACTTG
    TGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OMu01353
    Clone ID Related Accession (Same CDS sequence) NM_025977.3
    Accession Version NM_025977.3 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1212bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-02-21
    Organism Mus musculus(house mouse)
    Product coiled-coil domain-containing protein 159 isoform 2
    Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK011114.1 and BC120702.1. On Sep 3, 2009 this sequence version replaced NM_025977.2. Transcript Variant: This variant (2) uses a different splice site at the 5' end which results in the use of a downstream start codon, compared to variant 1. The resulting protein (isoform 2) has a shorter and distinct N-terminus when compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK011114.1, BC120702.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGAACGGGT GTGACTCTCT TTTGGCTGGC CTATCCCGGG ACTCTGACGA CTGTGTTTCT 
    CATCTCTGCA CACCTCCGTT ACTCGCCATC ACATCTTGGG CTGCTAAGGA GAGGAGCCAG
    TACTCACCAC CTCCTGGAGA GCCTGGGCCC TCCTCAGACA AGGCTTTGGA CTGTATGACC
    CACTGGTCCA GGGTTTTGGA GCCTGAGATC GTGAACACTG CTTCTGAACA AGCAGGGAAG
    TCTGGGGCCT GGGAGAAGGA GTGGGACTCA GAACCACAGC CTCATGAGGG TACACCCTGT
    TCCAGCTCAG ACGTGAACAA GGACCATTAT CATGACCAGG ACCTTGTGAA GAGGAACCAC
    TGTGTAGCCA AGAAGTCCCT GGAGCCCAGC TCAGCCAAAG TAAAAGTTAA GAACACCATG
    ATAATTCCTG ACTCTCAGAA GCTCTTGCGA TGCGAACTGG AGTCTCTCAG GAGCCAGCTG
    CAGGCTCAGA GCAAGGCTTT CGAGTTCCTG AATCACTCTG TGACCATGCT GGAGAAGGAG
    AGCTGCCTAC AGCAGATCAA GATTCAGCAG CTTGAAGAAG TGCTGAGCCC CACGAGCCGC
    CAAGGAGAGA AGTATGGCCG TAAGTGGAGC ACAGAGCAGG AGCTGTATGG GGCCCTGGCT
    CAAGGCCTGC AGGGGTTGCA GAAGACACTG AAGGAAGGCG AGGAGCTGCA ACGGGCCCGT
    ACCACTCGCT GCCTGCAGCT GTTGGCCCGG GAGATCCGGG ACAGCAAGAA GTTCCTGTGG
    GAGGAACTGG AGCTGGTGCG GGAAGAGGTG ACTTTCATCT ATCAGAAACT CCAGGACCAG
    GAGGATGAGA TCTCAGAGAA TCTCCTGAAT ATCCAGAAGA TGCAGAAAAC TCAGGTGAAG
    TGCCGCAAGG TTCTTACCAA GATGAAGCAG CAGGCATACG ATTCATGGCC AGAAGCCGAG
    GGGGTGCCCA CAGAAGGCAA CGGTTGCTGT AAGGATGACC TCCAGAAGGA GCTGGGTGAC
    ATATGGTCTG CCGTTCACAG TCTGCAGAGC TCCATTGACT GTCTTGCTTT GTCAATGGGC
    ACCAGACCCA GGGCCTCCAG CCTCAGAGGC CAGAAAGGAC ACCAGTGCAA GAGCTCTCAG
    TGCCCCTCCT GGGACTCCGA TTCAGACTGG GAGAGACCTT TCAGCAAGAG TGGATCCTAC
    CCTCCCGCTT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_080253.2
    CDS248..1459
    Translation

    Target ORF information:

    RefSeq Version NM_025977.3
    Organism Mus musculus(house mouse)
    Definition Mus musculus coiled-coil domain containing 159 (Ccdc159), transcript variant 2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_025977.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGAACGGGT GTGACTCTCT TTTGGCTGGC CTATCCCGGG ACTCTGACGA CTGTGTTTCT 
    CATCTCTGCA CACCTCCGTT ACTCGCCATC ACATCTTGGG CTGCTAAGGA GAGGAGCCAG
    TACTCACCAC CTCCTGGAGA GCCTGGGCCC TCCTCAGACA AGGCTTTGGA CTGTATGACC
    CACTGGTCCA GGGTTTTGGA GCCTGAGATC GTGAACACTG CTTCTGAACA AGCAGGGAAG
    TCTGGGGCCT GGGAGAAGGA GTGGGACTCA GAACCACAGC CTCATGAGGG TACACCCTGT
    TCCAGCTCAG ACGTGAACAA GGACCATTAT CATGACCAGG ACCTTGTGAA GAGGAACCAC
    TGTGTAGCCA AGAAGTCCCT GGAGCCCAGC TCAGCCAAAG TAAAAGTTAA GAACACCATG
    ATAATTCCTG ACTCTCAGAA GCTCTTGCGA TGCGAACTGG AGTCTCTCAG GAGCCAGCTG
    CAGGCTCAGA GCAAGGCTTT CGAGTTCCTG AATCACTCTG TGACCATGCT GGAGAAGGAG
    AGCTGCCTAC AGCAGATCAA GATTCAGCAG CTTGAAGAAG TGCTGAGCCC CACGAGCCGC
    CAAGGAGAGA AGTATGGCCG TAAGTGGAGC ACAGAGCAGG AGCTGTATGG GGCCCTGGCT
    CAAGGCCTGC AGGGGTTGCA GAAGACACTG AAGGAAGGCG AGGAGCTGCA ACGGGCCCGT
    ACCACTCGCT GCCTGCAGCT GTTGGCCCGG GAGATCCGGG ACAGCAAGAA GTTCCTGTGG
    GAGGAACTGG AGCTGGTGCG GGAAGAGGTG ACTTTCATCT ATCAGAAACT CCAGGACCAG
    GAGGATGAGA TCTCAGAGAA TCTCCTGAAT ATCCAGAAGA TGCAGAAAAC TCAGGTGAAG
    TGCCGCAAGG TTCTTACCAA GATGAAGCAG CAGGCATACG ATTCATGGCC AGAAGCCGAG
    GGGGTGCCCA CAGAAGGCAA CGGTTGCTGT AAGGATGACC TCCAGAAGGA GCTGGGTGAC
    ATATGGTCTG CCGTTCACAG TCTGCAGAGC TCCATTGACT GTCTTGCTTT GTCAATGGGC
    ACCAGACCCA GGGCCTCCAG CCTCAGAGGC CAGAAAGGAC ACCAGTGCAA GAGCTCTCAG
    TGCCCCTCCT GGGACTCCGA TTCAGACTGG GAGAGACCTT TCAGCAAGAG TGGATCCTAC
    CCTCCCGCTT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

  • PubMed

    A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
    PLoS biology9(1)e1000582(2011 Jan)
    Diez-Roux G,Banfi S,Sultan M,Geffers L,Anand S,Rozado D,Magen A,Canidio E,Pagani M,Peluso I,Lin-Marq N,Koch M,Bilio M,Cantiello I,Verde R,De Masi C,Bianchi SA,Cicchini J,Perroud E,Mehmeti S,Dagand E,Schrinner S,N?rnberger A,Schmidt K,Metz K,Zwingmann C,Brieske N,Springer C,Hernandez AM,Herzog S,Grabbe F,Sieverding C,Fischer B,Schrader K,Brockmeyer M,Dettmer S,Helbig C,Alunni V,Battaini MA,Mura C,Henrichsen CN,Garcia-Lopez R,Echevarria D,Puelles E,Garcia-Calero E,Kruse S,Uhr M,Kauck C,Feng G,Milyaev N,Ong CK,Kumar L,Lam M,Semple CA,Gyenesei A,Mundlos S,Radelof U,Lehrach H,Sarmientos P,Reymond A,Davidson DR,Doll? P,Antonarakis SE,Yaspo ML,Martinez S,Baldock RA,Eichele G,Ballabio A