Rwdd1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rwdd1
Entrez Gene ID	66521
Full Name	RWD domain containing 1
Synonyms	0710001K08Rik,2610002D06Rik,2700069A07Rik,IH1
General protein information	Preferred Names RWD domain containing 1 Names RWD domain-containing protein 1 DRG family-regulatory protein 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 10 Map Location: 10\|10 B1

mRNA and Protein(s)

mRNA	Protein	Name
NM_025614.3	NP_079890.1	RWD domain-containing protein 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	RWDD1	NP_057036.2
Caenorhabditis elegans (roundworm)	CELE_T26E3.4	NP_493207.1
	RWDD1	XP_001111296.1
Bos taurus (cattle)	RWDD1	NP_001029898.1
Drosophila melanogaster (fruit fly)	CG5515	NP_001262901.1
Oryza sativa (rice)	Os01g0558300	NP_001043334.1
Canis lupus familiaris (dog)	RWDD1	XP_851223.1
Xenopus tropicalis (tropical clawed frog)	rwdd1	NP_001005815.1
Pan troglodytes (chimpanzee)	RWDD1	XP_518709.2
Mus musculus (house mouse)	Rwdd1	NP_079890.1
Rattus norvegicus (Norway rat)	Rwdd1	NP_671487.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003063	XP_312750.4
Gallus gallus (chicken)	RWDD1	NP_001026246.2
Danio rerio (zebrafish)	rwdd1	NP_001002535.1
Arabidopsis thaliana (thale cress)	AT1G51730	NP_175584.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

RWDD1 interacts with the ligand binding domain of the androgen receptor and acts as a coactivator of androgen-dependent transactivation.
Gr?tsch H, Kunert M, Mooslehner KA, Gao Z, Struve D, Hughes IA, Hiort O, Werner R
Molecular and cellular endocrinology358(1)53-62(2012 Jul)

Rwdd1, a thymus aging related molecule, is a new member of the intrinsically unstructured protein family.
Kang N, Chen D, Wang L, Duan L, Liu S, Tang L, Liu Q, Cui L, He W
Cellular & molecular immunology5(5)333-9(2008 Oct)

Identification and characterization of a novel thymus aging related protein Rwdd1.
Kang N, Duan L, Tang L, Liu S, Li C, Li Y, Liu Q, Hu Y, Cui L, He W
Cellular & molecular immunology5(4)279-85(2008 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

data describe a new role for RWDD1 as androgen receptor (AR) coactivator; RWDD1 interacts with the androgen receptor in vitro and in vivo; AR ligand-binding dis sufficient for the interaction with RWDD1.
Title: RWDD1 interacts with the ligand binding domain of the androgen receptor and acts as a coactivator of androgen-dependent transactivation.

Rwdd1 is a novel member of the IUP family.
Title: Rwdd1, a thymus aging related molecule, is a new member of the intrinsically unstructured protein family.

Rwdd1 is a thymus involution related protein that may indirectly affect androgen receptor signaling pathway.
Title: Identification and characterization of a novel thymus aging related protein Rwdd1.

The following Rwdd1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rwdd1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu00769	NM_025614.3 Latest version!	Mus musculus RWD domain containing 1 (Rwdd1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rwdd1 ( NM_025614.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_079890.1 Mus musculus RWD domain containing 1 (Rwdd1), mRNA.

Price & Availability↑

CloneID	OMu00769
Clone ID Related Accession (Same CDS sequence)	NM_025614.3
Accession Version	NM_025614.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 732bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Mus musculus(house mouse)
Product	RWD domain-containing protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC153962.3. On Apr 29, 2007 this sequence version replaced NM_025614.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK011277.1, AK003262.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135 [ECO:0000348] ##Evidence-Data-END##

ATGACAGATT ACGGCGAGGA ACAACGCAAC GAGTTGGAGG CTCTGGAGTC CATCTACCCC 
GACTCCTTCA CAGTGTTATC AGAAAGCCCG CCAAGCTTCA CCATTACTGT GACATCGGAG 
GCTGGAGAAA ATGATGAAAC TGTCCAGACT ACTCTCAAGT TTACATACAG TGAAAAGTAC 
CCTGATGAGA CTCCACTTTA TGAAATATTC TCCCAGGAAA ATCTAGAAGA CAATGATGTC 
TCAGACATTT TAAAATTACT GGCATTGCAG GCCGAGGAGA ATCTCGGCAT GGTGATGATC 
TTCACCCTCG TGACAGCTGT TCAAGAAAAG TTAAATGAAA TAGTTGATCA GATCAAAACA 
AGAAGAGAGG AAGAAAAGAA GCAGAAAGAA AAGGAAGCAG AAGAAGCAGA GAAGAAACTG 
TTCCATGGCA CCCCTGTTAC GATTGAGAAT TTCTTGAGTT GGAAGGCCAA ATTTGATGCA 
GAACTCCTGG AAATTAAAAA GAAACGAATG AAAGAAGAGG AGCAAGCAGG GAAAAATAAA 
CTAAGTGGGA AACAGTTATT TGAAACAGAT CACAATCTTG ACACATCTGA TATCCAGTTC 
CTGGAGGATG CTGGGAACAA TGTGGAGGTG GATGAGTCAT TGTTCCAAGA AATGGACGAT 
TTGGAGCTAG AAGATGGTGA AGATGATCCT GACTACAATC CTGTTGCCCC AGGGAGTGAC 
TCCTCAGACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079890.1
CDS	179..910
Translation	MTDYGEEQRNELEALESIYPDSFTVLSESPPSFTITVTSEAGENDETVQTTLKFTYSEKYPDETPLYEIFSQENLEDNDVSDILKLLALQAEENLGMVMIFTLVTAVQEKLNEIVDQIKTRREEEKKQKEKEAEEAEKKLFHGTPVTIENFLSWKAKFDAELLEIKKKRMKEEEQAGKNKLSGKQLFETDHNLDTSDIQFLEDAGNNVEVDESLFQEMDDLELEDGEDDPDYNPVAPGSDSSD

Target ORF information:

RefSeq Version	NM_025614.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus RWD domain containing 1 (Rwdd1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025614.3

ORF Insert Sequence:

ATGACAGATT ACGGCGAGGA ACAACGCAAC GAGTTGGAGG CTCTGGAGTC CATCTACCCC 
GACTCCTTCA CAGTGTTATC AGAAAGCCCG CCAAGCTTCA CCATTACTGT GACATCGGAG 
GCTGGAGAAA ATGATGAAAC TGTCCAGACT ACTCTCAAGT TTACATACAG TGAAAAGTAC 
CCTGATGAGA CTCCACTTTA TGAAATATTC TCCCAGGAAA ATCTAGAAGA CAATGATGTC 
TCAGACATTT TAAAATTACT GGCATTGCAG GCCGAGGAGA ATCTCGGCAT GGTGATGATC 
TTCACCCTCG TGACAGCTGT TCAAGAAAAG TTAAATGAAA TAGTTGATCA GATCAAAACA 
AGAAGAGAGG AAGAAAAGAA GCAGAAAGAA AAGGAAGCAG AAGAAGCAGA GAAGAAACTG 
TTCCATGGCA CCCCTGTTAC GATTGAGAAT TTCTTGAGTT GGAAGGCCAA ATTTGATGCA 
GAACTCCTGG AAATTAAAAA GAAACGAATG AAAGAAGAGG AGCAAGCAGG GAAAAATAAA 
CTAAGTGGGA AACAGTTATT TGAAACAGAT CACAATCTTG ACACATCTGA TATCCAGTTC 
CTGGAGGATG CTGGGAACAA TGTGGAGGTG GATGAGTCAT TGTTCCAAGA AATGGACGAT 
TTGGAGCTAG AAGATGGTGA AGATGATCCT GACTACAATC CTGTTGCCCC AGGGAGTGAC 
TCCTCAGACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

RWDD1 interacts with the ligand binding domain of the androgen receptor and acts as a coactivator of androgen-dependent transactivation.
Molecular and cellular endocrinology358(1)53-62(2012 Jul)
Gr?tsch H,Kunert M,Mooslehner KA,Gao Z,Struve D,Hughes IA,Hiort O,Werner R

Rwdd1, a thymus aging related molecule, is a new member of the intrinsically unstructured protein family.
Cellular & molecular immunology5(5)333-9(2008 Oct)
Kang N,Chen D,Wang L,Duan L,Liu S,Tang L,Liu Q,Cui L,He W

Identification and characterization of a novel thymus aging related protein Rwdd1.
Cellular & molecular immunology5(4)279-85(2008 Aug)
Kang N,Duan L,Tang L,Liu S,Li C,Li Y,Liu Q,Hu Y,Cui L,He W

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Rwdd1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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