Rnase2b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rnase2b
Entrez Gene ID	54159
Full Name	ribonuclease, RNase A family, 2B (liver, eosinophil-derived neurotoxin)
Synonyms	Ear5,Raf4,mR5
General protein information	Preferred Names ribonuclease, RNase A family, 2B (liver, eosinophil-derived neurotoxin) Names ribonuclease 2B MR-5 eosinophil cationic-type ribonuclease 5 eosinophil-associated ribonuclease 5 eosinophil-associated, ribonuclease A family, member 5 murine ribonuclease 5 ribonuclease A f4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 14 Map Location: 14\|14 C1

mRNA and Protein(s)

mRNA	Protein	Name
NM_019398.2	NP_062271.2	ribonuclease 2B precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	RNASE3	XP_005211584.1
Mus musculus (house mouse)	Ear11	NP_444343.2
Mus musculus (house mouse)	Ear5	NP_062271.2
	RNASE2	XP_001094839.1
Homo sapiens (human)	RNASE2	NP_002925.1
Pan troglodytes (chimpanzee)	RNASE2	NP_001009133.1

Gene Ontology
Bibliography

Related articles in PubMed

Mouse eosinophil associated ribonucleases: Mechanism of cytotoxic, antibacterial and antiparasitic activities.
Attery A, Batra JK
International journal of biological macromolecules94(Pt A)445-450(2017 Jan)

Comparative genomic analysis of eutherian ribonuclease A genes.
Premzl M
Molecular genetics and genomics : MGG289(2)161-7(2014 Apr)

Comprehensive analysis of the transcriptional landscape of the human FMR1 gene reveals two new long noncoding RNAs differentially expressed in Fragile X syndrome and Fragile X-associated tremor/ataxia syndrome.
Pastori C, Peschansky VJ, Barbouth D, Mehta A, Silva JP, Wahlestedt C
Human genetics133(1)59-67(2014 Jan)

The ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories.
Cho S, Beintema JJ, Zhang J
Genomics85(2)208-20(2005 Feb)

Identification of a purine-rich intronic enhancer element in the mouse eosinophil-associated ribonuclease 2 (mEar 2) gene.
Dyer KD, Nitto T, Moreau JM, McDevitt AL, Rosenberg HF
Mammalian genome : official journal of the International Mammalian Genome Society15(2)126-34(2004 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Functional activity of four mouse eosinophil associated ribonucleases, mEAR2, mEAR5, mEAR7 and mEAR11.
Title: Mouse eosinophil associated ribonucleases: Mechanism of cytotoxic, antibacterial and antiparasitic activities.

two novel lncRNAs, FMR5 and FMR6, are differentially expressed in Fragile X syndrome and Fragile X-associated tremor/ataxia syndrome
Title: Comprehensive analysis of the transcriptional landscape of the human FMR1 gene reveals two new long noncoding RNAs differentially expressed in Fragile X syndrome and Fragile X-associated tremor/ataxia syndrome.

The following Rnase2b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rnase2b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu17882	NM_019398.2 Latest version!	Mus musculus ribonuclease, RNase A family, 2B (liver, eosinophil-derived neurotoxin) (Rnase2b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rnase2b ( NM_019398.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_062271.2 Mus musculus ribonuclease, RNase A family, 2B (liver, eosinophil-derived neurotoxin) (Rnase2b), mRNA.

Price & Availability↑

CloneID	OMu17882
Clone ID Related Accession (Same CDS sequence)	NM_019398.2
Accession Version	NM_019398.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 468bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	ribonuclease 2B precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC163664.3. On Aug 21, 2009 this sequence version replaced NM_019398.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript is intronless :: BC117776.2 [ECO:0000345] ##Evidence-Data-END##

ATGGGTCTGA AGCTGCTTGA ATCCAGACTT TGTCTCCTGC TGCTGCTGGG ACTTGTCCTA 
ACGCTTGTCT CATGCCAGCG ACCAACCCCT TCCCAGAAGT TTGACATCCA GCATATCTAT 
AAGAAATCCT CTCCCAAATG TGATGATGCA ATGCGGGTCG TTAACAAGTA TACAGGAAAA 
TGTAAGGACT TGAATACTTT TCTTCATACA ACTTTTGCTG ATGTTGTCCG TGTGTGTCAC 
AATCCACCCA AGACTTGCAA AGACGGGACA AGTCCAAATT GTCATGATAG TTCATCTAAG 
GTATCTGTAA CTATCTGTAA ACTCACAAAA CGGGCAAGGA ATTATACCCA CTGCAGATAC 
AAAACAACAG GAGCAAAGAA GTCCTACACA GTTGCCTGTA ACCCCAGAAC TCCAAAGGAC 
CGTCCCACCT ATCCAGTAGT TCCGGTTCAC TTGGATCGGC TATTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062271.2
CDS	205..672
Translation	MGLKLLESRLCLLLLLGLVLTLVSCQRPTPSQKFDIQHIYKKSSPKCDDAMRVVNKYTGKCKDLNTFLHTTFADVVRVCHNPPKTCKDGTSPNCHDSSSKVSVTICKLTKRARNYTHCRYKTTGAKKSYTVACNPRTPKDRPTYPVVPVHLDRLF

Target ORF information:

RefSeq Version	NM_019398.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ribonuclease, RNase A family, 2B (liver, eosinophil-derived neurotoxin) (Rnase2b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019398.2

ORF Insert Sequence:

ATGGGTCTGA AGCTGCTTGA ATCCAGACTT TGTCTCCTGC TGCTGCTGGG ACTTGTCCTA 
ACGCTTGTCT CATGCCAGCG ACCAACCCCT TCCCAGAAGT TTGACATCCA GCATATCTAT 
AAGAAATCCT CTCCCAAATG TGATGATGCA ATGCGGGTCG TTAACAAGTA TACAGGAAAA 
TGTAAGGACT TGAATACTTT TCTTCATACA ACTTTTGCTG ATGTTGTCCG TGTGTGTCAC 
AATCCACCCA AGACTTGCAA AGACGGGACA AGTCCAAATT GTCATGATAG TTCATCTAAG 
GTATCTGTAA CTATCTGTAA ACTCACAAAA CGGGCAAGGA ATTATACCCA CTGCAGATAC 
AAAACAACAG GAGCAAAGAA GTCCTACACA GTTGCCTGTA ACCCCAGAAC TCCAAAGGAC 
CGTCCCACCT ATCCAGTAGT TCCGGTTCAC TTGGATCGGC TATTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mouse eosinophil associated ribonucleases: Mechanism of cytotoxic, antibacterial and antiparasitic activities.
International journal of biological macromolecules94(Pt A)445-450(2017 Jan)
Attery A,Batra JK

Comparative genomic analysis of eutherian ribonuclease A genes.
Molecular genetics and genomics : MGG289(2)161-7(2014 Apr)
Premzl M

Comprehensive analysis of the transcriptional landscape of the human FMR1 gene reveals two new long noncoding RNAs differentially expressed in Fragile X syndrome and Fragile X-associated tremor/ataxia syndrome.
Human genetics133(1)59-67(2014 Jan)
Pastori C,Peschansky VJ,Barbouth D,Mehta A,Silva JP,Wahlestedt C

The ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories.
Genomics85(2)208-20(2005 Feb)
Cho S,Beintema JJ,Zhang J

Identification of a purine-rich intronic enhancer element in the mouse eosinophil-associated ribonuclease 2 (mEar 2) gene.
Mammalian genome : official journal of the International Mammalian Genome Society15(2)126-34(2004 Feb)
Dyer KD,Nitto T,Moreau JM,McDevitt AL,Rosenberg HF