Tsnax cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tsnax
Entrez Gene ID	53424
Full Name	translin-associated factor X
Synonyms	R74833,Trax
General protein information	Preferred Names translin-associated factor X Names translin-associated protein X
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8 E2\|8 73.1 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_016909.2	NP_058605.1	translin-associated protein X
NM_016909.3	NP_058605.1	translin-associated protein X

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TSNAX	XP_514271.3
Canis lupus familiaris (dog)	TSNAX	XP_536345.2
Drosophila melanogaster (fruit fly)	Trax	NP_732021.2
Magnaporthe oryzae (rice blast fungus)	MGG_09242	XP_003709868.1
Rattus norvegicus (Norway rat)	Tsnax	NP_071598.1
Bos taurus (cattle)	TSNAX	NP_001069474.2
Danio rerio (zebrafish)	tsnax	NP_001025275.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004585	XP_315244.4
Homo sapiens (human)	TSNAX	NP_005990.1
Xenopus tropicalis (tropical clawed frog)	tsnax	NP_001006778.1
	TSNAX	XP_001104647.1
Mus musculus (house mouse)	Tsnax	NP_058605.1
Gallus gallus (chicken)	TSNAX	NP_001006403.1
Neurospora crassa	NCU06059	XP_959822.1
Arabidopsis thaliana (thale cress)	AT2G03780	NP_178473.2
Oryza sativa (rice)	Os01g0265900	NP_001042673.2

Gene Ontology
Bibliography

Related articles in PubMed

Learning induces the translin/trax RNase complex to express activin receptors for persistent memory.
Park AJ, Havekes R, Fu X, Hansen R, Tudor JC, Peixoto L, Li Z, Wu YC, Poplawski SG, Baraban JM, Abel T
eLife6(2017 Sep)

A central role of TRAX in the ATM-mediated DNA repair.
Wang JY, Chen SY, Sun CN, Chien T, Chern Y
Oncogene35(13)1657-70(2016 Mar)

RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly.
Lo JC, Jamsai D, O'Connor AE, Borg C, Clark BJ, Whisstock JC, Field MC, Adams V, Ishikawa T, Aitken RJ, Whittle B, Goodnow CC, Ormandy CJ, O'Bryan MK
PLoS genetics8(10)e1002969(2012)

Analysis of nucleic acid binding by a recombinant translin-trax complex.
Lluis M, Hoe W, Schleit J, Robertus J
Biochemical and biophysical research communications396(3)709-13(2010 Jun)

Rescue of p53 blockage by the A(2A) adenosine receptor via a novel interacting protein, translin-associated protein X.
Sun CN, Cheng HC, Chou JL, Lee SY, Lin YW, Lai HL, Chen HM, Chern Y
Molecular pharmacology70(2)454-66(2006 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

TRAX is required for DNA repair, by interacting with activated ATM and protects cells from genotoxic stress-induced apoptosis.
Title: A central role of TRAX in the ATM-mediated DNA repair.

trax acts to regulate translin's RNA and DNA binding affinities as part of a cellular RNA trafficking mechanism.
Title: Analysis of nucleic acid binding by a recombinant translin-trax complex.

Trax was found to accumulate in the Golgi complex of mid-late pachytene spermatocytes
Title: Co-localization of Trax and Mea2 in Golgi complex of pachytene spermatocytes in the mouse.

subcellular locations of TB-RBP and TRAX in male germ cells are modulated by the relative ratios of TRAX and TB-RBP
Title: The relative levels of translin-associated factor X (TRAX) and testis brain RNA-binding protein determine their nucleocytoplasmic distribution in male germ cells.

TRAX is post-transcriptionally stabilized by TB-RBP and both proteins are needed for normal cell proliferation
Title: Translin-associated factor X is post-transcriptionally regulated by its partner protein TB-RBP, and both are essential for normal cell proliferation.

The following Tsnax gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tsnax cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu10705	NM_016909.3 Latest version!	Mus musculus translin-associated factor X (Tsnax), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OMu10705	NM_016909.2	Mus musculus translin-associated factor X (Tsnax), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tsnax ( NM_016909.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_058605.1 Mus musculus translin-associated factor X (Tsnax), mRNA.

Price & Availability↑

CloneID	OMu10705
Clone ID Related Accession (Same CDS sequence)	NM_016909.2 , NM_016909.3
Accession Version	NM_016909.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 873bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-24
Organism	Mus musculus(house mouse)
Product	translin-associated protein X
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL672234.27. On Nov 17, 2006 this sequence version replaced NM_016909.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF187040.1, AK159223.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGAACGGCA AAGAAGGACC AGGAGGGTTC AGGAAGAGGA AGCATGACAC CTTCCCACAT 
AACCAAAGGA GAGAGGGGAA GGATGCCAGT TTGTCTTCGC CGGTGATGCT GGCCTTCAAA 
TCATTTCAGC AGGAGCTGGA CGCCAGGCAC GACAAATATG AGAGACTCGT GAAGCTAAGC 
CGGGATATTA CTGTGGAGAG TAAGAGGACA ATTTTTCTTC TCCATAGGAT TACAAGTGCT 
CCTGATATGG AGGAGATACT GACTGAATCA GAAAGTAAGC TGGATGGTGT CAGACAGAAG 
ATCCTGCAGG TAGCCCAAGA GCTGTCGGGG GAAGACATGC ACCAGTTCCA TCGAGCCGTC 
ACCACAGGAC TGCAGGAATA CGTGGAGGCT GTCTCTTTTC AACACTTCAT CAAAACTCGT 
TCATTGATCA GTATGGAAGA GATTAACAAG CAGTTGACAT TTACAGCAGA AGACAGTGGG 
AAAGAGAGCA AGACTCCTCC CGCGGAAGGA CAAGAGAAGC AGCTGGTTAC ATGGAGACTG 
AAGCTCACCC CTGTTGACTA CCTGCTGGGC GTGGCCGACC TAACTGGAGA GTTGATGCGG 
ATGTGTATTA ACAGTGTGGG GAACGGGGAC ATCGACACCC CCTTTGAAGT GAGCCAGTTT 
TTACGCCAGG TTTACGATGG GTTCTCGTTC ATTGGCAACA CTGGGCCCTA TGAGGTCTCT 
AAGAAGCTGT ACACCTTGAA ACAGAGCCTG GCCAAAGTGG AGAACGCTTG CTATGCCCTT 
AAAGTCCGGG GTTCTGAGAT TCCTAAGCAC ATGCTGGCAG ATGTGTTTTC AGTTAAAACA 
GACATGATTG ATCAGGAAGA GAGCATTTCT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058605.1
CDS	201..1073
Translation	MNGKEGPGGFRKRKHDTFPHNQRREGKDASLSSPVMLAFKSFQQELDARHDKYERLVKLSRDITVESKRTIFLLHRITSAPDMEEILTESESKLDGVRQKILQVAQELSGEDMHQFHRAVTTGLQEYVEAVSFQHFIKTRSLISMEEINKQLTFTAEDSGKESKTPPAEGQEKQLVTWRLKLTPVDYLLGVADLTGELMRMCINSVGNGDIDTPFEVSQFLRQVYDGFSFIGNTGPYEVSKKLYTLKQSLAKVENACYALKVRGSEIPKHMLADVFSVKTDMIDQEESIS

Target ORF information:

RefSeq Version	NM_016909.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus translin-associated factor X (Tsnax), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016909.2

ORF Insert Sequence:

ATGAACGGCA AAGAAGGACC AGGAGGGTTC AGGAAGAGGA AGCATGACAC CTTCCCACAT 
AACCAAAGGA GAGAGGGGAA GGATGCCAGT TTGTCTTCGC CGGTGATGCT GGCCTTCAAA 
TCATTTCAGC AGGAGCTGGA CGCCAGGCAC GACAAATATG AGAGACTCGT GAAGCTAAGC 
CGGGATATTA CTGTGGAGAG TAAGAGGACA ATTTTTCTTC TCCATAGGAT TACAAGTGCT 
CCTGATATGG AGGAGATACT GACTGAATCA GAAAGTAAGC TGGATGGTGT CAGACAGAAG 
ATCCTGCAGG TAGCCCAAGA GCTGTCGGGG GAAGACATGC ACCAGTTCCA TCGAGCCGTC 
ACCACAGGAC TGCAGGAATA CGTGGAGGCT GTCTCTTTTC AACACTTCAT CAAAACTCGT 
TCATTGATCA GTATGGAAGA GATTAACAAG CAGTTGACAT TTACAGCAGA AGACAGTGGG 
AAAGAGAGCA AGACTCCTCC CGCGGAAGGA CAAGAGAAGC AGCTGGTTAC ATGGAGACTG 
AAGCTCACCC CTGTTGACTA CCTGCTGGGC GTGGCCGACC TAACTGGAGA GTTGATGCGG 
ATGTGTATTA ACAGTGTGGG GAACGGGGAC ATCGACACCC CCTTTGAAGT GAGCCAGTTT 
TTACGCCAGG TTTACGATGG GTTCTCGTTC ATTGGCAACA CTGGGCCCTA TGAGGTCTCT 
AAGAAGCTGT ACACCTTGAA ACAGAGCCTG GCCAAAGTGG AGAACGCTTG CTATGCCCTT 
AAAGTCCGGG GTTCTGAGAT TCCTAAGCAC ATGCTGGCAG ATGTGTTTTC AGTTAAAACA 
GACATGATTG ATCAGGAAGA GAGCATTTCT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tsnax ( NM_016909.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_058605.1 Mus musculus translin-associated factor X (Tsnax), mRNA.

Price & Availability↑

CloneID	OMu10705
Clone ID Related Accession (Same CDS sequence)	NM_016909.2 , NM_016909.3
Accession Version	NM_016909.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 873bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Mus musculus(house mouse)
Product	translin-associated protein X
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL672234.27. On Feb 7, 2019 this sequence version replaced NM_016909.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7345562.2516076.1, SRR7345562.4771418.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGAACGGCA AAGAAGGACC AGGAGGGTTC AGGAAGAGGA AGCATGACAC CTTCCCACAT 
AACCAAAGGA GAGAGGGGAA GGATGCCAGT TTGTCTTCGC CGGTGATGCT GGCCTTCAAA 
TCATTTCAGC AGGAGCTGGA CGCCAGGCAC GACAAATATG AGAGACTCGT GAAGCTAAGC 
CGGGATATTA CTGTGGAGAG TAAGAGGACA ATTTTTCTTC TCCATAGGAT TACAAGTGCT 
CCTGATATGG AGGAGATACT GACTGAATCA GAAAGTAAGC TGGATGGTGT CAGACAGAAG 
ATCCTGCAGG TAGCCCAAGA GCTGTCGGGG GAAGACATGC ACCAGTTCCA TCGAGCCGTC 
ACCACAGGAC TGCAGGAATA CGTGGAGGCT GTCTCTTTTC AACACTTCAT CAAAACTCGT 
TCATTGATCA GTATGGAAGA GATTAACAAG CAGTTGACAT TTACAGCAGA AGACAGTGGG 
AAAGAGAGCA AGACTCCTCC CGCGGAAGGA CAAGAGAAGC AGCTGGTTAC ATGGAGACTG 
AAGCTCACCC CTGTTGACTA CCTGCTGGGC GTGGCCGACC TAACTGGAGA GTTGATGCGG 
ATGTGTATTA ACAGTGTGGG GAACGGGGAC ATCGACACCC CCTTTGAAGT GAGCCAGTTT 
TTACGCCAGG TTTACGATGG GTTCTCGTTC ATTGGCAACA CTGGGCCCTA TGAGGTCTCT 
AAGAAGCTGT ACACCTTGAA ACAGAGCCTG GCCAAAGTGG AGAACGCTTG CTATGCCCTT 
AAAGTCCGGG GTTCTGAGAT TCCTAAGCAC ATGCTGGCAG ATGTGTTTTC AGTTAAAACA 
GACATGATTG ATCAGGAAGA GAGCATTTCT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058605.1
CDS	157..1029
Translation	MNGKEGPGGFRKRKHDTFPHNQRREGKDASLSSPVMLAFKSFQQELDARHDKYERLVKLSRDITVESKRTIFLLHRITSAPDMEEILTESESKLDGVRQKILQVAQELSGEDMHQFHRAVTTGLQEYVEAVSFQHFIKTRSLISMEEINKQLTFTAEDSGKESKTPPAEGQEKQLVTWRLKLTPVDYLLGVADLTGELMRMCINSVGNGDIDTPFEVSQFLRQVYDGFSFIGNTGPYEVSKKLYTLKQSLAKVENACYALKVRGSEIPKHMLADVFSVKTDMIDQEESIS

Target ORF information:

RefSeq Version	NM_016909.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus translin-associated factor X (Tsnax), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016909.3

ORF Insert Sequence:

ATGAACGGCA AAGAAGGACC AGGAGGGTTC AGGAAGAGGA AGCATGACAC CTTCCCACAT 
AACCAAAGGA GAGAGGGGAA GGATGCCAGT TTGTCTTCGC CGGTGATGCT GGCCTTCAAA 
TCATTTCAGC AGGAGCTGGA CGCCAGGCAC GACAAATATG AGAGACTCGT GAAGCTAAGC 
CGGGATATTA CTGTGGAGAG TAAGAGGACA ATTTTTCTTC TCCATAGGAT TACAAGTGCT 
CCTGATATGG AGGAGATACT GACTGAATCA GAAAGTAAGC TGGATGGTGT CAGACAGAAG 
ATCCTGCAGG TAGCCCAAGA GCTGTCGGGG GAAGACATGC ACCAGTTCCA TCGAGCCGTC 
ACCACAGGAC TGCAGGAATA CGTGGAGGCT GTCTCTTTTC AACACTTCAT CAAAACTCGT 
TCATTGATCA GTATGGAAGA GATTAACAAG CAGTTGACAT TTACAGCAGA AGACAGTGGG 
AAAGAGAGCA AGACTCCTCC CGCGGAAGGA CAAGAGAAGC AGCTGGTTAC ATGGAGACTG 
AAGCTCACCC CTGTTGACTA CCTGCTGGGC GTGGCCGACC TAACTGGAGA GTTGATGCGG 
ATGTGTATTA ACAGTGTGGG GAACGGGGAC ATCGACACCC CCTTTGAAGT GAGCCAGTTT 
TTACGCCAGG TTTACGATGG GTTCTCGTTC ATTGGCAACA CTGGGCCCTA TGAGGTCTCT 
AAGAAGCTGT ACACCTTGAA ACAGAGCCTG GCCAAAGTGG AGAACGCTTG CTATGCCCTT 
AAAGTCCGGG GTTCTGAGAT TCCTAAGCAC ATGCTGGCAG ATGTGTTTTC AGTTAAAACA 
GACATGATTG ATCAGGAAGA GAGCATTTCT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Learning induces the translin/trax RNase complex to express activin receptors for persistent memory.
eLife6(2017 Sep)
Park AJ,Havekes R,Fu X,Hansen R,Tudor JC,Peixoto L,Li Z,Wu YC,Poplawski SG,Baraban JM,Abel T

A central role of TRAX in the ATM-mediated DNA repair.
Oncogene35(13)1657-70(2016 Mar)
Wang JY,Chen SY,Sun CN,Chien T,Chern Y

RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly.
PLoS genetics8(10)e1002969(2012)
Lo JC,Jamsai D,O'Connor AE,Borg C,Clark BJ,Whisstock JC,Field MC,Adams V,Ishikawa T,Aitken RJ,Whittle B,Goodnow CC,Ormandy CJ,O'Bryan MK

Analysis of nucleic acid binding by a recombinant translin-trax complex.
Biochemical and biophysical research communications396(3)709-13(2010 Jun)
Lluis M,Hoe W,Schleit J,Robertus J

Rescue of p53 blockage by the A(2A) adenosine receptor via a novel interacting protein, translin-associated protein X.
Molecular pharmacology70(2)454-66(2006 Aug)
Sun CN,Cheng HC,Chou JL,Lee SY,Lin YW,Lai HL,Chen HM,Chern Y

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Tsnax cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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