Copb2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Copb2
Entrez Gene ID	50797
Full Name	coatomer protein complex, subunit beta 2 (beta prime)
Synonyms	AI256832
General protein information	Preferred Names coatomer protein complex, subunit beta 2 (beta prime) Names coatomer subunit beta' beta'-COP beta'-coat protein p102
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 9 Map Location: 9\|9 E3.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_015827.2	NP_056642.1	coatomer subunit beta'

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	COPB2	XP_005634562.1
Gallus gallus (chicken)	COPB2	XP_422637.2
Bos taurus (cattle)	COPB2	NP_776706.2
Mus musculus (house mouse)	Copb2	NP_056642.1
Rattus norvegicus (Norway rat)	Copb2	NP_068533.1
Saccharomyces cerevisiae (baker's yeast)	SEC27	NP_011378.1
Eremothecium gossypii	AGOS_AFL118W	NP_985432.1
Schizosaccharomyces pombe (fission yeast)	sec27	XP_001713153.1
Magnaporthe oryzae (rice blast fungus)	MGG_10504	XP_003710112.1
Neurospora crassa	NCU07319	XP_962477.1
Arabidopsis thaliana (thale cress)	AT3G15980	NP_001189907.1
Oryza sativa (rice)	Os06g0143900	NP_001056779.1
Danio rerio (zebrafish)	copb2	NP_001001940.1
Drosophila melanogaster (fruit fly)	beta'Cop	NP_524836.2
Xenopus tropicalis (tropical clawed frog)	copb2	NP_001027518.1
Homo sapiens (human)	COPB2	NP_004757.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004798	XP_318012.4
Arabidopsis thaliana (thale cress)	AT1G52360	NP_175645.1
Arabidopsis thaliana (thale cress)	AT1G79990	NP_001154478.1
Pan troglodytes (chimpanzee)	COPB2	XP_003310064.1
Caenorhabditis elegans (roundworm)	CELE_F38E11.5	NP_501671.1
Kluyveromyces lactis	KLLA0B01958g	XP_451618.1

Gene Ontology
Bibliography

Related articles in PubMed

Copb2 is essential for embryogenesis and hypomorphic mutations cause human microcephaly.
DiStasio A, Driver A, Sund K, Donlin M, Muraleedharan RM, Pooya S, Kline-Fath B, Kaufman KM, Prows CA, Schorry E, Dasgupta B, Stottmann RW
Human molecular genetics26(24)4836-4848(2017 Dec)

A piggyBac insertion disrupts Foxl2 expression that mimics BPES syndrome in mice.
Shi F, Ding S, Zhao S, Han M, Zhuang Y, Xu T, Wu X
Human molecular genetics23(14)3792-800(2014 Jul)

CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells.
Slater LH, Hett EC, Clatworthy AE, Mark KG, Hung DT
Proceedings of the National Academy of Sciences of the United States of America110(24)9932-7(2013 Jun)

A new role for the muscle repair protein dysferlin in endothelial cell adhesion and angiogenesis.
Sharma A, Yu C, Leung C, Trane A, Lau M, Utokaparch S, Shaheen F, Sheibani N, Bernatchez P
Arteriosclerosis, thrombosis, and vascular biology30(11)2196-204(2010 Nov)

Mammalian Bet3 functions as a cytosolic factor participating in transport from the ER to the Golgi apparatus.
Loh E, Peter F, Subramaniam VN, Hong W
Journal of cell science118(Pt 6)1209-22(2005 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Copb2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Copb2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu10363	NM_015827.2 Latest version!	Mus musculus coatomer protein complex, subunit beta 2 (beta prime) (Copb2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$531.30 $759.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Copb2 ( NM_015827.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_056642.1 Mus musculus coatomer protein complex, subunit beta 2 (beta prime) (Copb2), mRNA.

Price & Availability↑

CloneID	OMu10363
Clone ID Related Accession (Same CDS sequence)	NM_015827.2
Accession Version	NM_015827.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2718bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	coatomer subunit beta'
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK088064.1. On Apr 6, 2007 this sequence version replaced NM_015827.1. ##Evidence-Data-START## Transcript exon combination :: AK088064.1, AK153352.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGCCTCTTC GACTTGACAT CAAGAGAAAG CTGACTGCTA GGTCTGACCG AGTTAAGAGC 
GTGGATTTGC ATCCCACAGA GCCATGGATG TTGGCTAGTC TTTACAATGG CAGTGTGTGT 
GTTTGGAATC ATGAAACTCA GACACTGGTG AAGACGTTTG AAGTATGTGA TCTTCCTGTT 
CGAGCTGCAA AGTTTGTCGC AAGGAAGAAC TGGGTGGTGA CAGGAGCAGA CGATATGCAG 
ATCAGAGTGT TCAATTATAA CACCCTGGAG AGGGTGCATA TGTTTGAAGC ACACTCGGAT 
TACATTCGTT GTATTGCTGT TCATCCCACC CAGCCGTTCA TTCTCACCAG CAGTGATGAC 
ATGCTTATTA AGCTCTGGGA CTGGGATAAA AAATGGTCTT GTTCACAAGT GTTTGAAGGA 
CACACGCACT ACGTTATGCA GATTGTGATA AACCCCAAAG ATAACAATCA GTTTGCCAGT 
GCATCTCTCG ACAGGACCAT CAAGGTGTGG CAGCTGGGCT CCTCATCACC AAACTTCACT 
CTGGAAGGAC ATGAAAAAGG CGTGAATTGC ATTGACTACT ACAGTGGTGG TGACAAGCCA 
TACCTCATTT CAGGTGCAGA TGACCGGCTT GTTAAAATAT GGGATTATCA GAACAAAACG 
TGTGTGCAGA CCCTGGAGGG GCATGCCCAG AATGTGTCGT GTGCGAGCTT CCATCCTGAG 
CTGCCCATCA TCATCACAGG GTCAGAAGAC GGAACTGTGC GAATCTGGCA TTCTAGCACC 
TACCGGCTTG AGAGCACGCT GAATTACGGA ATGGAGAGGG TGTGGTGTGT GGCCAGTCTG 
AGAGGGTCCA ACAATGTCGC TCTGGGCTAT GATGAAGGGA GCATCATTGT TAAGCTTGGT 
CGGGAGGAAC CTGCCATGTC CATGGATGCC AATGGAAAGA TAATCTGGGC CAAGCATTCA 
GAAGTCCAGC AGGCCAACCT GAAAGCAATG GGTGACACTG AGATTAAAGA TGGAGAAAGA 
TTGCCACTGG CAGTAAAGGA CATGGGCAGT TGTGAAATAT ATCCACAGAC CATTCAGCAC 
AATCCTAATG GGAGGTTTGT TGTGGTATGT GGTGATGGGG AGTATATCAT CTACACAGCA 
ATGGCATTGA GGAACAAGAG CTTCGGGTCT GCCCAGGAGT TTGCATGGGC CCACGATTCT 
TCAGAGTATG CAATAAGAGA AAGCAACAGT ATTGTAAAGA TATTTAAAAA CTTTAAGGAA 
AAAAAATCAT TTAAACCCGA TTTTGGAGCT GAAAGTATCT ATGGGGGCTT CTTGCTGGGA 
GTCAGATCTG TAAATGGCTT AGCCTTCTAT GACTGGGAGA ATACTGAACT CATCCGCAGA 
ATTGAAATTC AGCCCAAGCA CATCTTCTGG TCTGACTCTG GAGAGCTGGT CTGTATCGCC 
ACCGAGGAGT CATTTTTTAT TCTTAAATAT CTGTCAGAAA AAGTCTTGGC TGCACAGGAA 
ACACATGAGG GAGTTACTGA AGATGGCATT GAAGACGCCT TTGAGGTTCT TGGTGAAATT 
CAGGAAATTG TGAAAACTGG GCTGTGGGTA GGTGACTGCT TCATTTACAC AAGTTCTGTG 
AACAGATTAA ACTATTACGT GGGAGGAGAG ATAGTCACCA TCGCCCACCT GGACAGGACA 
ATGTATCTTC TGGGCTATAT TCCAAAAGAC AATAGACTTT ATCTGGGGGA TAAGGAATTG 
AATATTGTTA GCTACTCCCT GTTGGTTTCA GTCCTGGAAT ACCAGACTGC TGTCATGCGG 
AGGGATTTTA GCATGGCGGA TAAAGTCCTC CCTACCATCC CCAAAGAACA GAGGACCAGA 
GTTGCACACT TTTTGGAAAA ACAGGGCTTC AAGCAGCAAG CACTTACAGT ATCCACAGAT 
CCTGAACATC GTTTTGAGCT TGCTCTTCAA CTTGGAGAGT TGAAAATTGC TTACCAGTTA 
GCAGTGGAAG CAGAGTCGGA GCAGAAGTGG AAACAACTTG CTGAACTTGC CATTAGTAAA 
TGTCAGTTCA GCCTAGCCCA GGAGTGTCTG CACCATGCTC AGGATTATGG TGGTCTGCTG 
CTCTTGGCCA CTGCTTCTGG AAATGCTAGT ATGGTGAACA AGCTGGCAGA AGGTGCGGAG 
AGAGACGGCA AAAATAACGT GGCATTCATG AGCTATTTTT TACAGGGCAA GCTTGATGCT 
TGCCTAGAGC TCTTGATCAG AACAGGAAGA CTCCCAGAAG CTGCCTTCCT GGCCCGAACT 
TACTTACCCA GTCAGGTCTC AAGGGTGGTG AAACTGTGGA GGGAGAATCT CTCAAAAGTC 
AACCAGAAAG CAGCAGAATC CCTTGCTGAT CCTACAGAGT ATGAAAACCT TTTCCCTGGA 
TTAAAAGAAG CCTTTGTTGT TGAAGAATGG GTGAAGGAGA CACATGCGGA TTTGTGGCCA 
GCCAAGCAGT ACCCTCTTGT CACGCCAAAT GAAGAGAGAA ATGTTATGGA AGAGGCAAAA 
GGCTTTCAGC CCTCAAGACC CACAGCCCAG CAGGAACCTG ATGGAAAACC TGCTTCTAGC 
CCAGTTATCA TGGCCTCCCA AACTACCCAC AAAGAAGAAA AGAGTTTACT AGAACTAGAA 
GTTGATTTGG ATAACTTGGA ATTAGAGGAT ATTGACACAA CAGACATTAA TCTGGATGAA 
GATATTCTGG ATGATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056642.1
CDS	91..2808
Translation	MPLRLDIKRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVASLRGSNNVALGYDEGSIIVKLGREEPAMSMDANGKIIWAKHSEVQQANLKAMGDTEIKDGERLPLAVKDMGSCEIYPQTIQHNPNGRFVVVCGDGEYIIYTAMALRNKSFGSAQEFAWAHDSSEYAIRESNSIVKIFKNFKEKKSFKPDFGAESIYGGFLLGVRSVNGLAFYDWENTELIRRIEIQPKHIFWSDSGELVCIATEESFFILKYLSEKVLAAQETHEGVTEDGIEDAFEVLGEIQEIVKTGLWVGDCFIYTSSVNRLNYYVGGEIVTIAHLDRTMYLLGYIPKDNRLYLGDKELNIVSYSLLVSVLEYQTAVMRRDFSMADKVLPTIPKEQRTRVAHFLEKQGFKQQALTVSTDPEHRFELALQLGELKIAYQLAVEAESEQKWKQLAELAISKCQFSLAQECLHHAQDYGGLLLLATASGNASMVNKLAEGAERDGKNNVAFMSYFLQGKLDACLELLIRTGRLPEAAFLARTYLPSQVSRVVKLWRENLSKVNQKAAESLADPTEYENLFPGLKEAFVVEEWVKETHADLWPAKQYPLVTPNEERNVMEEAKGFQPSRPTAQQEPDGKPASSPVIMASQTTHKEEKSLLELEVDLDNLELEDIDTTDINLDEDILDD

Target ORF information:

RefSeq Version	NM_015827.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus coatomer protein complex, subunit beta 2 (beta prime) (Copb2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015827.2

ORF Insert Sequence:

ATGCCTCTTC GACTTGACAT CAAGAGAAAG CTGACTGCTA GGTCTGACCG AGTTAAGAGC 
GTGGATTTGC ATCCCACAGA GCCATGGATG TTGGCTAGTC TTTACAATGG CAGTGTGTGT 
GTTTGGAATC ATGAAACTCA GACACTGGTG AAGACGTTTG AAGTATGTGA TCTTCCTGTT 
CGAGCTGCAA AGTTTGTCGC AAGGAAGAAC TGGGTGGTGA CAGGAGCAGA CGATATGCAG 
ATCAGAGTGT TCAATTATAA CACCCTGGAG AGGGTGCATA TGTTTGAAGC ACACTCGGAT 
TACATTCGTT GTATTGCTGT TCATCCCACC CAGCCGTTCA TTCTCACCAG CAGTGATGAC 
ATGCTTATTA AGCTCTGGGA CTGGGATAAA AAATGGTCTT GTTCACAAGT GTTTGAAGGA 
CACACGCACT ACGTTATGCA GATTGTGATA AACCCCAAAG ATAACAATCA GTTTGCCAGT 
GCATCTCTCG ACAGGACCAT CAAGGTGTGG CAGCTGGGCT CCTCATCACC AAACTTCACT 
CTGGAAGGAC ATGAAAAAGG CGTGAATTGC ATTGACTACT ACAGTGGTGG TGACAAGCCA 
TACCTCATTT CAGGTGCAGA TGACCGGCTT GTTAAAATAT GGGATTATCA GAACAAAACG 
TGTGTGCAGA CCCTGGAGGG GCATGCCCAG AATGTGTCGT GTGCGAGCTT CCATCCTGAG 
CTGCCCATCA TCATCACAGG GTCAGAAGAC GGAACTGTGC GAATCTGGCA TTCTAGCACC 
TACCGGCTTG AGAGCACGCT GAATTACGGA ATGGAGAGGG TGTGGTGTGT GGCCAGTCTG 
AGAGGGTCCA ACAATGTCGC TCTGGGCTAT GATGAAGGGA GCATCATTGT TAAGCTTGGT 
CGGGAGGAAC CTGCCATGTC CATGGATGCC AATGGAAAGA TAATCTGGGC CAAGCATTCA 
GAAGTCCAGC AGGCCAACCT GAAAGCAATG GGTGACACTG AGATTAAAGA TGGAGAAAGA 
TTGCCACTGG CAGTAAAGGA CATGGGCAGT TGTGAAATAT ATCCACAGAC CATTCAGCAC 
AATCCTAATG GGAGGTTTGT TGTGGTATGT GGTGATGGGG AGTATATCAT CTACACAGCA 
ATGGCATTGA GGAACAAGAG CTTCGGGTCT GCCCAGGAGT TTGCATGGGC CCACGATTCT 
TCAGAGTATG CAATAAGAGA AAGCAACAGT ATTGTAAAGA TATTTAAAAA CTTTAAGGAA 
AAAAAATCAT TTAAACCCGA TTTTGGAGCT GAAAGTATCT ATGGGGGCTT CTTGCTGGGA 
GTCAGATCTG TAAATGGCTT AGCCTTCTAT GACTGGGAGA ATACTGAACT CATCCGCAGA 
ATTGAAATTC AGCCCAAGCA CATCTTCTGG TCTGACTCTG GAGAGCTGGT CTGTATCGCC 
ACCGAGGAGT CATTTTTTAT TCTTAAATAT CTGTCAGAAA AAGTCTTGGC TGCACAGGAA 
ACACATGAGG GAGTTACTGA AGATGGCATT GAAGACGCCT TTGAGGTTCT TGGTGAAATT 
CAGGAAATTG TGAAAACTGG GCTGTGGGTA GGTGACTGCT TCATTTACAC AAGTTCTGTG 
AACAGATTAA ACTATTACGT GGGAGGAGAG ATAGTCACCA TCGCCCACCT GGACAGGACA 
ATGTATCTTC TGGGCTATAT TCCAAAAGAC AATAGACTTT ATCTGGGGGA TAAGGAATTG 
AATATTGTTA GCTACTCCCT GTTGGTTTCA GTCCTGGAAT ACCAGACTGC TGTCATGCGG 
AGGGATTTTA GCATGGCGGA TAAAGTCCTC CCTACCATCC CCAAAGAACA GAGGACCAGA 
GTTGCACACT TTTTGGAAAA ACAGGGCTTC AAGCAGCAAG CACTTACAGT ATCCACAGAT 
CCTGAACATC GTTTTGAGCT TGCTCTTCAA CTTGGAGAGT TGAAAATTGC TTACCAGTTA 
GCAGTGGAAG CAGAGTCGGA GCAGAAGTGG AAACAACTTG CTGAACTTGC CATTAGTAAA 
TGTCAGTTCA GCCTAGCCCA GGAGTGTCTG CACCATGCTC AGGATTATGG TGGTCTGCTG 
CTCTTGGCCA CTGCTTCTGG AAATGCTAGT ATGGTGAACA AGCTGGCAGA AGGTGCGGAG 
AGAGACGGCA AAAATAACGT GGCATTCATG AGCTATTTTT TACAGGGCAA GCTTGATGCT 
TGCCTAGAGC TCTTGATCAG AACAGGAAGA CTCCCAGAAG CTGCCTTCCT GGCCCGAACT 
TACTTACCCA GTCAGGTCTC AAGGGTGGTG AAACTGTGGA GGGAGAATCT CTCAAAAGTC 
AACCAGAAAG CAGCAGAATC CCTTGCTGAT CCTACAGAGT ATGAAAACCT TTTCCCTGGA 
TTAAAAGAAG CCTTTGTTGT TGAAGAATGG GTGAAGGAGA CACATGCGGA TTTGTGGCCA 
GCCAAGCAGT ACCCTCTTGT CACGCCAAAT GAAGAGAGAA ATGTTATGGA AGAGGCAAAA 
GGCTTTCAGC CCTCAAGACC CACAGCCCAG CAGGAACCTG ATGGAAAACC TGCTTCTAGC 
CCAGTTATCA TGGCCTCCCA AACTACCCAC AAAGAAGAAA AGAGTTTACT AGAACTAGAA 
GTTGATTTGG ATAACTTGGA ATTAGAGGAT ATTGACACAA CAGACATTAA TCTGGATGAA 
GATATTCTGG ATGATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Copb2 is essential for embryogenesis and hypomorphic mutations cause human microcephaly.
Human molecular genetics26(24)4836-4848(2017 Dec)
DiStasio A,Driver A,Sund K,Donlin M,Muraleedharan RM,Pooya S,Kline-Fath B,Kaufman KM,Prows CA,Schorry E,Dasgupta B,Stottmann RW

A piggyBac insertion disrupts Foxl2 expression that mimics BPES syndrome in mice.
Human molecular genetics23(14)3792-800(2014 Jul)
Shi F,Ding S,Zhao S,Han M,Zhuang Y,Xu T,Wu X

CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells.
Proceedings of the National Academy of Sciences of the United States of America110(24)9932-7(2013 Jun)
Slater LH,Hett EC,Clatworthy AE,Mark KG,Hung DT

A new role for the muscle repair protein dysferlin in endothelial cell adhesion and angiogenesis.
Arteriosclerosis, thrombosis, and vascular biology30(11)2196-204(2010 Nov)
Sharma A,Yu C,Leung C,Trane A,Lau M,Utokaparch S,Shaheen F,Sheibani N,Bernatchez P

Mammalian Bet3 functions as a cytosolic factor participating in transport from the ER to the Golgi apparatus.
Journal of cell science118(Pt 6)1209-22(2005 Mar)
Loh E,Peter F,Subramaniam VN,Hong W

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Copb2 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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