Tmem102 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tmem102
Entrez Gene ID	380705
Full Name	transmembrane protein 102
Synonyms	4632403M07Rik,Cbap,Tmem102-ps
General protein information	Preferred Names transmembrane protein 102 Names transmembrane protein 102 transmembrane protein 102, pseudogene
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11\|11 B3

mRNA and Protein(s)

mRNA	Protein	Name
NM_001033433.4	NP_001028605.2	transmembrane protein 102

Pathways from BioSystems

Homologies

Bos taurus (cattle)	TMEM102	NP_001068812.1
Rattus norvegicus (Norway rat)	Tmem102	XP_573124.4
Homo sapiens (human)	TMEM102	NP_848613.1
Pan troglodytes (chimpanzee)	TMEM102	XP_001170143.1
Canis lupus familiaris (dog)	TMEM102	XP_546590.3
Mus musculus (house mouse)	Tmem102	NP_001028605.2
	TMEM102	XP_001108700.1

Gene Ontology
Bibliography

Related articles in PubMed

CBAP promotes thymocyte negative selection by facilitating T-cell receptor proximal signaling.
Ho KC, Chiang YJ, Lai AC, Liao NS, Chang YJ, Yang-Yen HF, Yen JJ
Cell death & disease5e1518(2014 Nov)

CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration.
Chiang YJ, Ho KC, Sun CT, Chiu JJ, Lee FJ, Liao F, Yang-Yen HF, Yen JJ
PloS one8(4)e61761(2013)

CBAP interacts with the un-liganded common beta-subunit of the GM-CSF/IL-3/IL-5 receptor and induces apoptosis via mitochondrial dysfunction.
Kao CJ, Chiang YJ, Chen PH, Lin KR, Hwang PI, Yang-Yen HF, Yen JJ
Oncogene27(10)1397-403(2008 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

CBAP is a novel component in the TCR signaling pathway, and it modulates thymocyte apoptosis during negative selection.
Title: CBAP promotes thymocyte negative selection by facilitating T-cell receptor proximal signaling.

CBAP indeed can function as a novel signaling component within the ZAP70/Vav1/talin complex and plays an important role in regulating chemokine-promoted T-cell trafficking.
Title: CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration.

Shows functional evidence for the homologous human protein.
Title: CBAP interacts with the un-liganded common beta-subunit of the GM-CSF/IL-3/IL-5 receptor and induces apoptosis via mitochondrial dysfunction.

The following Tmem102 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tmem102 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu12672	NM_001033433.4 Latest version!	Mus musculus transmembrane protein 102 (Tmem102), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tmem102 ( NM_001033433.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001028605.2 Mus musculus transmembrane protein 102 (Tmem102), mRNA.

Price & Availability↑

CloneID	OMu12672
Clone ID Related Accession (Same CDS sequence)	NM_001033433.4
Accession Version	NM_001033433.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1530bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-21
Organism	Mus musculus(house mouse)
Product	transmembrane protein 102
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK143262.1, AL603707.5 and CK032079.1. On Jun 9, 2010 this sequence version replaced NM_001033433.3. ##Evidence-Data-START## Transcript exon combination :: AK143262.1, BQ951571.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTTCCA CCGTCTGGGG GGGTGCCCCC TGGTGGGGAC CACCGCCCCC AGCCCCAGCC 
CGGCCTCTCA CAGACATAGA TTTCTGCTCG GGCGCCCAGC TGCAGGAGCT CACTCAGTTA 
ATTCAGGAGC TCCGTGTTCA GGAGAGTTGG AGTGAAGGGC CCAAGCCTGG AGCTGATCTT 
CTCCGAGCCA AGGATTTTGT CTTCGCTCTA CTCGGTCTGG TTCACCGCCA AGACCCTCGT 
TTTCCACCCC AGGCAGAACT CTTGCTGCTT CGTGGTGGGA TTCGCGAAGG TTCCCTAGAT 
TTAGGGCACG CCCCCTTAGG TCCCTACTCC CGGGGACCTC ATTATGATGC CGGCTTTACA 
CTCCTTGTGC CTGTGTTTTC TCTGGATGGC ACTGGGCCCG AGCTGCTACT GGATCTGGAA 
TCCTGTTCTG CATGGCTCCG CCTTCCAGAA CTGATGCGTG GAATTTTGGT CCGGGAGGCC 
TGGCAGGATT GCTTAGGACC TCCTGTCCCA GAAGAAAGTG ATATGACTCA CCAAACCCAT 
AGCAAAGAGA GTCCCACCGA CCGGGAAAAC TCTGTAGATC CGTCACATGA TTATGTCCCT 
GAACCTGAGC CACACATGTC TTTGCAAAAA TCATCTAGTG ACCTTTCAGA GTCCCAATCG 
TCTTATAAGG ACATTACCAA TCCTGAAACT CCTGAGCCAT TGGAAACACT GAGCAGCGAC 
GCCTTGGACG CCGACGAAAG CCAAGTCCCA AAGCCGTCGG AGGCTCCAAA GGCATGGCCC 
ACATTATGCC CGACCCAAGT AACTTCCTGG TTCTTCGTTA AGTTGGCTGA GGTTGCTGAG 
TCCCTGATCC CGGTCCCAGG CGCCCCACGG CTAGTTCATG CAGCTCGTCA CGCAGGTGTC 
ACCACGGTCC TCCTGGCAAC TCCAGAGCCC CCACGCCACC TCCTGCTCTT CGACTTGATC 
CCGGTGGTGA CCGTGACAGG CTGGCCTGAC ACGGCTCGGA GCCACTCGTG GGCGGGTCCA 
CTGGTCTCTG AATCGGCCTC TTTCTACCTA GTGCCGGGCA GCCTCCCAGA GCAGCCGAGC 
ACCTCTGGAT GGCAGCTGTG CTTCGCTCGC CAGGAGCTGG CGCTCAAAGA GCGCATCCCC 
ACGCCGCTGC TTCAGGCACA CGCGGCGGCC CAGGCGCTGC TGCGCCCGCT GGTGGCGGGG 
ACCCGAGCCG CTGCGCCCTA CCTCCTGCGG ACCTTGCTCT ACTGGGCGTG CGAGCGGCTC 
CCGGCGCTCT ACTTGGCGCG GCCGGAAAAT GCCGGCGCTT GTTGCCTTGG GCTACTGGAT 
GAGCTGAGCC GAGTGCTAGA GGCCGGGGCG CTGCCTCATT ATTTTTTGAG CGGCCGAAAG 
CTCCGTGTGG GAGACGGCTC CGCTGCTCTG CGCGGGGCAT TGGCCCAGCT CCGCGGGGAC 
CCTGCACAGG CCTTGCGTGA GGCTGTAGAG GAAGCCAAGG TTGCCCGCAA AGGGGGCGGT 
TTAGCGGGCG TAGGGGGCGG GACCCATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001028605.2
CDS	392..1921
Translation	MASTVWGGAPWWGPPPPAPARPLTDIDFCSGAQLQELTQLIQELRVQESWSEGPKPGADLLRAKDFVFALLGLVHRQDPRFPPQAELLLLRGGIREGSLDLGHAPLGPYSRGPHYDAGFTLLVPVFSLDGTGPELLLDLESCSAWLRLPELMRGILVREAWQDCLGPPVPEESDMTHQTHSKESPTDRENSVDPSHDYVPEPEPHMSLQKSSSDLSESQSSYKDITNPETPEPLETLSSDALDADESQVPKPSEAPKAWPTLCPTQVTSWFFVKLAEVAESLIPVPGAPRLVHAARHAGVTTVLLATPEPPRHLLLFDLIPVVTVTGWPDTARSHSWAGPLVSESASFYLVPGSLPEQPSTSGWQLCFARQELALKERIPTPLLQAHAAAQALLRPLVAGTRAAAPYLLRTLLYWACERLPALYLARPENAGACCLGLLDELSRVLEAGALPHYFLSGRKLRVGDGSAALRGALAQLRGDPAQALREAVEEAKVARKGGGLAGVGGGTH

Target ORF information:

RefSeq Version	NM_001033433.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus transmembrane protein 102 (Tmem102), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001033433.4

ORF Insert Sequence:

ATGGCTTCCA CCGTCTGGGG GGGTGCCCCC TGGTGGGGAC CACCGCCCCC AGCCCCAGCC 
CGGCCTCTCA CAGACATAGA TTTCTGCTCG GGCGCCCAGC TGCAGGAGCT CACTCAGTTA 
ATTCAGGAGC TCCGTGTTCA GGAGAGTTGG AGTGAAGGGC CCAAGCCTGG AGCTGATCTT 
CTCCGAGCCA AGGATTTTGT CTTCGCTCTA CTCGGTCTGG TTCACCGCCA AGACCCTCGT 
TTTCCACCCC AGGCAGAACT CTTGCTGCTT CGTGGTGGGA TTCGCGAAGG TTCCCTAGAT 
TTAGGGCACG CCCCCTTAGG TCCCTACTCC CGGGGACCTC ATTATGATGC CGGCTTTACA 
CTCCTTGTGC CTGTGTTTTC TCTGGATGGC ACTGGGCCCG AGCTGCTACT GGATCTGGAA 
TCCTGTTCTG CATGGCTCCG CCTTCCAGAA CTGATGCGTG GAATTTTGGT CCGGGAGGCC 
TGGCAGGATT GCTTAGGACC TCCTGTCCCA GAAGAAAGTG ATATGACTCA CCAAACCCAT 
AGCAAAGAGA GTCCCACCGA CCGGGAAAAC TCTGTAGATC CGTCACATGA TTATGTCCCT 
GAACCTGAGC CACACATGTC TTTGCAAAAA TCATCTAGTG ACCTTTCAGA GTCCCAATCG 
TCTTATAAGG ACATTACCAA TCCTGAAACT CCTGAGCCAT TGGAAACACT GAGCAGCGAC 
GCCTTGGACG CCGACGAAAG CCAAGTCCCA AAGCCGTCGG AGGCTCCAAA GGCATGGCCC 
ACATTATGCC CGACCCAAGT AACTTCCTGG TTCTTCGTTA AGTTGGCTGA GGTTGCTGAG 
TCCCTGATCC CGGTCCCAGG CGCCCCACGG CTAGTTCATG CAGCTCGTCA CGCAGGTGTC 
ACCACGGTCC TCCTGGCAAC TCCAGAGCCC CCACGCCACC TCCTGCTCTT CGACTTGATC 
CCGGTGGTGA CCGTGACAGG CTGGCCTGAC ACGGCTCGGA GCCACTCGTG GGCGGGTCCA 
CTGGTCTCTG AATCGGCCTC TTTCTACCTA GTGCCGGGCA GCCTCCCAGA GCAGCCGAGC 
ACCTCTGGAT GGCAGCTGTG CTTCGCTCGC CAGGAGCTGG CGCTCAAAGA GCGCATCCCC 
ACGCCGCTGC TTCAGGCACA CGCGGCGGCC CAGGCGCTGC TGCGCCCGCT GGTGGCGGGG 
ACCCGAGCCG CTGCGCCCTA CCTCCTGCGG ACCTTGCTCT ACTGGGCGTG CGAGCGGCTC 
CCGGCGCTCT ACTTGGCGCG GCCGGAAAAT GCCGGCGCTT GTTGCCTTGG GCTACTGGAT 
GAGCTGAGCC GAGTGCTAGA GGCCGGGGCG CTGCCTCATT ATTTTTTGAG CGGCCGAAAG 
CTCCGTGTGG GAGACGGCTC CGCTGCTCTG CGCGGGGCAT TGGCCCAGCT CCGCGGGGAC 
CCTGCACAGG CCTTGCGTGA GGCTGTAGAG GAAGCCAAGG TTGCCCGCAA AGGGGGCGGT 
TTAGCGGGCG TAGGGGGCGG GACCCATTAA