Tmc4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tmc4
Entrez Gene ID	353499
Full Name	transmembrane channel-like gene family 4
General protein information	Preferred Names transmembrane channel-like gene family 4 Names transmembrane channel-like protein 4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 A1

mRNA and Protein(s)

mRNA	Protein	Name
NM_181820.2	NP_861541.2	transmembrane channel-like protein 4

Pathways from BioSystems

Homologies

Homo sapiens (human)	TMC4	NP_001138775.2
Pan troglodytes (chimpanzee)	TMC4	XP_003316705.1
Canis lupus familiaris (dog)	TMC4	XP_541427.4
Mus musculus (house mouse)	Tmc4	NP_861541.2

Gene Ontology
Bibliography

Related articles in PubMed

Transcriptome analysis of mouse stem cells and early embryos.
Sharov AA, Piao Y, Matoba R, Dudekula DB, Qian Y, VanBuren V, Falco G, Martin PR, Stagg CA, Bassey UC, Wang Y, Carter MG, Hamatani T, Aiba K, Akutsu H, Sharova L, Tanaka TS, Kimber WL, Yoshikawa T, Jaradat SA, Pantano S, Nagaraja R, Boheler KR, Taub D, Hodes RJ, Longo DL, Schlessinger D, Keller J, Klotz E, Kelsoe G, Umezawa A, Vescovi AL, Rossant J, Kunath T, Hogan BL, Curci A, D'Urso M, Kelso J, Hide W, Ko MS
PLoS biology1(3)E74(2003 Dec)

Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformis.
Kurima K, Yang Y, Sorber K, Griffith AJ
Genomics82(3)300-8(2003 Sep)

TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins.
Keresztes G, Mutai H, Heller S
BMC genomics4(1)24(2003 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Tmc4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tmc4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu08182	NM_181820.2 Latest version!	Mus musculus transmembrane channel-like gene family 4 (Tmc4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tmc4 ( NM_181820.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_861541.2 Mus musculus transmembrane channel-like gene family 4 (Tmc4), mRNA.

Price & Availability↑

CloneID	OMu08182
Clone ID Related Accession (Same CDS sequence)	NM_181820.2
Accession Version	NM_181820.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2085bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Mus musculus(house mouse)
Product	transmembrane channel-like protein 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB600173.1, AK050105.1 and CN719678.1. On Oct 12, 2006 this sequence version replaced NM_181820.1. ##Evidence-Data-START## Transcript exon combination :: BC040466.1, AY236493.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849377, SAMN01164134 [ECO:0000348] ##Evidence-Data-END##

ATGGAAGCCT GGGGCCAGTC CCCAGCCTGC TCCAGCTCCC GGAAAGCCAG AACAGGCCCA 
TCGCTGGCGT CTGTGCTGAA CGATCTCCCC AGCGCTGCTA CGCTGCGATA CCGCGGCCCT 
GGTGTGCTCC CTTGGGGAAC ACTGGATGAA GATGATGATG AAGGAGGAAG GAGCCTTCAG 
GCCTTTGCAG AAACTGCACA AATGGAATCT CACCCTTCCC GGGAACTTCC CTGGCCTATG 
CAGGCAAGGC GGGCACACAG GAAGAGCCAG GCTACAGGGC AGCTGGCTTC TGGCTCTGAA 
TCCAGGGCTG CCTACTGGAC CCGACAGCTT TCCCGGACCA AGGGAAAAAT GAAAGAAGGC 
TTTCAAACTA TACAGCCCTG GGCATGGACG CTGAAGAAAA TTGGGGGTCA GTTTGGAGCA 
GGCACTGAGT CCTACTTCTC CCTGCTGCGC TTCCTGCTCT TTCTCAACCT GGTGGCATCT 
GTCATTGAAA TCTGCATGAA GCTGATCCCC ACCTGGCTGG AAGGGGCTCC TCCAGGTCCC 
CCTGGCCCTA ACATCTCTTC ACCCTGTGGT TCCTATATTC CACACACTCA TGGCCTGGTC 
GCCTTCCCCA CCCAGCTTTT CAACTTGCTC TCTGGAGAGG GTTACCTTGA GTGGTCCCCT 
CTATTCTATG GGTTCTACCC ACCCCGATCG AACCTGGCCA TCACCTACCT GTGCTCCGTC 
TTTGCCATCA GCATCATCTA CTTGCTGTGC ATCCTACGAC GTTCGGTGTC CGGGTTGAAG 
GAGACACTGT TGGCGGAGTC AGACATTCTG ACCAGCTACA GTCACCGAGT GTTCTCAGCT 
TGGAATTTTG GCCTCTGCGG GGACGTGCAC GTGCGGCTGC GCCAGCGCAT CATTTTGTAT 
GAACTACAGG TGGACCTAGA GGAAGCAGTA GTCCGGCGCC GTGCTGCGGA GCAGACTCTG 
AGCCAACGAG CCAAGGTGTG GTCGATGAGG GCGCTGCTCA ACGTGCTGGT CCTCGCGCTG 
CTCGGGGCGG CCTTCTATGG CATCTACTGG GCCACCGAGT ACACCTTGAC ACTACAGGAG 
ACGCCCCTTG TCCGACAGAC CCCACTATTC AAGCTTCTGG TGGATTATCT ACCATCCATC 
TTCATTTCTC TGTTCAACTT TGTGCTGCCT CCTGTGTTCA AGTTCATTGC CTCACTAGAG 
GGCTACACTC AAAGCCGACA GATCGTCTTG ATCCTGCTTA GGACTGTGTT TTTGCGTCTG 
GCCTCGCTGG TGTTCCTTCT GGTCTCTCTG TGGAGTCAGA TCACGTGTGG GGGAAACATG 
GAGGCAGAAG GATGCAAGGC CTGCGGCTAT AATTACAAAG AAATTCCGTG CTGGGAGACT 
CGGCTGGGCC AGGAGATGTA CAAACTTGTA CTCTTTGATC TGCTGATGGG CCTGTTGGTC 
ACGCTGTTGG TCCAGTTTCC TAGGAAGATA CTCTGTGGCC TCTGTCCTGG GGCACTGGGT 
CGTCTGTCGG GAACCCTGGA GTTCCAGGTG CCAGATGAGG TGCTGGGGCT CATCTATGCG 
CAGACCGTGG TCTGGGTGGG AAGCTTCTTC TGCCCTTTAC TGCCTTTGAT CAACACTGCT 
AAGTTCCTCA TACTGTTCTG CCTGAAGAAG ATAACCCTCT TCTCCATCTA CTCACCGGCT 
TCCCGCACCT TCCGAGCATC CACGGCAAAC TTCTTTTTCC CCCTGGTTCT CCTTGTGGGT 
CTGGCGATCT CTGCAGTTCC CGTGCTTTAC AGTATCTTCC TGATCCCACC TTCGAAACTG 
TGTGGCCCGT TCCGCGGGAA GCTGTCCATT TGGGCCCAGA TCCCTGAGGC CATTGAGAGC 
CTCCCTCAGA CTGCCCAGAA TTTTCTCTAC TTTCTGGGAA CCCAAGCTTT TACTGTACCT 
CTTCTGATCC TCTCTAGCAT CCTGATGATG TATACCGTAG CCCTGGCTAA CTGTTACGGA 
CGCCTCATCT CTGAGCTCAA ACGCCAGATA GAGACGGAAG TGCAGAATAA AGTCTTCCTG 
GCCCAGCGAG CTGTGGCTCT GAGCTCAAGG AATGGAACTT CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_861541.2
CDS	76..2160
Translation	MEAWGQSPACSSSRKARTGPSLASVLNDLPSAATLRYRGPGVLPWGTLDEDDDEGGRSLQAFAETAQMESHPSRELPWPMQARRAHRKSQATGQLASGSESRAAYWTRQLSRTKGKMKEGFQTIQPWAWTLKKIGGQFGAGTESYFSLLRFLLFLNLVASVIEICMKLIPTWLEGAPPGPPGPNISSPCGSYIPHTHGLVAFPTQLFNLLSGEGYLEWSPLFYGFYPPRSNLAITYLCSVFAISIIYLLCILRRSVSGLKETLLAESDILTSYSHRVFSAWNFGLCGDVHVRLRQRIILYELQVDLEEAVVRRRAAEQTLSQRAKVWSMRALLNVLVLALLGAAFYGIYWATEYTLTLQETPLVRQTPLFKLLVDYLPSIFISLFNFVLPPVFKFIASLEGYTQSRQIVLILLRTVFLRLASLVFLLVSLWSQITCGGNMEAEGCKACGYNYKEIPCWETRLGQEMYKLVLFDLLMGLLVTLLVQFPRKILCGLCPGALGRLSGTLEFQVPDEVLGLIYAQTVVWVGSFFCPLLPLINTAKFLILFCLKKITLFSIYSPASRTFRASTANFFFPLVLLVGLAISAVPVLYSIFLIPPSKLCGPFRGKLSIWAQIPEAIESLPQTAQNFLYFLGTQAFTVPLLILSSILMMYTVALANCYGRLISELKRQIETEVQNKVFLAQRAVALSSRNGTS

Target ORF information:

RefSeq Version	NM_181820.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus transmembrane channel-like gene family 4 (Tmc4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181820.2

ORF Insert Sequence:

ATGGAAGCCT GGGGCCAGTC CCCAGCCTGC TCCAGCTCCC GGAAAGCCAG AACAGGCCCA 
TCGCTGGCGT CTGTGCTGAA CGATCTCCCC AGCGCTGCTA CGCTGCGATA CCGCGGCCCT 
GGTGTGCTCC CTTGGGGAAC ACTGGATGAA GATGATGATG AAGGAGGAAG GAGCCTTCAG 
GCCTTTGCAG AAACTGCACA AATGGAATCT CACCCTTCCC GGGAACTTCC CTGGCCTATG 
CAGGCAAGGC GGGCACACAG GAAGAGCCAG GCTACAGGGC AGCTGGCTTC TGGCTCTGAA 
TCCAGGGCTG CCTACTGGAC CCGACAGCTT TCCCGGACCA AGGGAAAAAT GAAAGAAGGC 
TTTCAAACTA TACAGCCCTG GGCATGGACG CTGAAGAAAA TTGGGGGTCA GTTTGGAGCA 
GGCACTGAGT CCTACTTCTC CCTGCTGCGC TTCCTGCTCT TTCTCAACCT GGTGGCATCT 
GTCATTGAAA TCTGCATGAA GCTGATCCCC ACCTGGCTGG AAGGGGCTCC TCCAGGTCCC 
CCTGGCCCTA ACATCTCTTC ACCCTGTGGT TCCTATATTC CACACACTCA TGGCCTGGTC 
GCCTTCCCCA CCCAGCTTTT CAACTTGCTC TCTGGAGAGG GTTACCTTGA GTGGTCCCCT 
CTATTCTATG GGTTCTACCC ACCCCGATCG AACCTGGCCA TCACCTACCT GTGCTCCGTC 
TTTGCCATCA GCATCATCTA CTTGCTGTGC ATCCTACGAC GTTCGGTGTC CGGGTTGAAG 
GAGACACTGT TGGCGGAGTC AGACATTCTG ACCAGCTACA GTCACCGAGT GTTCTCAGCT 
TGGAATTTTG GCCTCTGCGG GGACGTGCAC GTGCGGCTGC GCCAGCGCAT CATTTTGTAT 
GAACTACAGG TGGACCTAGA GGAAGCAGTA GTCCGGCGCC GTGCTGCGGA GCAGACTCTG 
AGCCAACGAG CCAAGGTGTG GTCGATGAGG GCGCTGCTCA ACGTGCTGGT CCTCGCGCTG 
CTCGGGGCGG CCTTCTATGG CATCTACTGG GCCACCGAGT ACACCTTGAC ACTACAGGAG 
ACGCCCCTTG TCCGACAGAC CCCACTATTC AAGCTTCTGG TGGATTATCT ACCATCCATC 
TTCATTTCTC TGTTCAACTT TGTGCTGCCT CCTGTGTTCA AGTTCATTGC CTCACTAGAG 
GGCTACACTC AAAGCCGACA GATCGTCTTG ATCCTGCTTA GGACTGTGTT TTTGCGTCTG 
GCCTCGCTGG TGTTCCTTCT GGTCTCTCTG TGGAGTCAGA TCACGTGTGG GGGAAACATG 
GAGGCAGAAG GATGCAAGGC CTGCGGCTAT AATTACAAAG AAATTCCGTG CTGGGAGACT 
CGGCTGGGCC AGGAGATGTA CAAACTTGTA CTCTTTGATC TGCTGATGGG CCTGTTGGTC 
ACGCTGTTGG TCCAGTTTCC TAGGAAGATA CTCTGTGGCC TCTGTCCTGG GGCACTGGGT 
CGTCTGTCGG GAACCCTGGA GTTCCAGGTG CCAGATGAGG TGCTGGGGCT CATCTATGCG 
CAGACCGTGG TCTGGGTGGG AAGCTTCTTC TGCCCTTTAC TGCCTTTGAT CAACACTGCT 
AAGTTCCTCA TACTGTTCTG CCTGAAGAAG ATAACCCTCT TCTCCATCTA CTCACCGGCT 
TCCCGCACCT TCCGAGCATC CACGGCAAAC TTCTTTTTCC CCCTGGTTCT CCTTGTGGGT 
CTGGCGATCT CTGCAGTTCC CGTGCTTTAC AGTATCTTCC TGATCCCACC TTCGAAACTG 
TGTGGCCCGT TCCGCGGGAA GCTGTCCATT TGGGCCCAGA TCCCTGAGGC CATTGAGAGC 
CTCCCTCAGA CTGCCCAGAA TTTTCTCTAC TTTCTGGGAA CCCAAGCTTT TACTGTACCT 
CTTCTGATCC TCTCTAGCAT CCTGATGATG TATACCGTAG CCCTGGCTAA CTGTTACGGA 
CGCCTCATCT CTGAGCTCAA ACGCCAGATA GAGACGGAAG TGCAGAATAA AGTCTTCCTG 
GCCCAGCGAG CTGTGGCTCT GAGCTCAAGG AATGGAACTT CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Transcriptome analysis of mouse stem cells and early embryos.
PLoS biology1(3)E74(2003 Dec)
Sharov AA,Piao Y,Matoba R,Dudekula DB,Qian Y,VanBuren V,Falco G,Martin PR,Stagg CA,Bassey UC,Wang Y,Carter MG,Hamatani T,Aiba K,Akutsu H,Sharova L,Tanaka TS,Kimber WL,Yoshikawa T,Jaradat SA,Pantano S,Nagaraja R,Boheler KR,Taub D,Hodes RJ,Longo DL,Schlessinger D,Keller J,Klotz E,Kelsoe G,Umezawa A,Vescovi AL,Rossant J,Kunath T,Hogan BL,Curci A,D'Urso M,Kelso J,Hide W,Ko MS

Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformis.
Genomics82(3)300-8(2003 Sep)
Kurima K,Yang Y,Sorber K,Griffith AJ

TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins.
BMC genomics4(1)24(2003 Jun)
Keresztes G,Mutai H,Heller S