Oas2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Oas2
Entrez Gene ID	246728
Full Name	2'-5' oligoadenylate synthetase 2
Synonyms	Oasl11
General protein information	Preferred Names 2'-5' oligoadenylate synthetase 2 Names 2'-5'-oligoadenylate synthase 2 (2-5')oligo(A) synthase 2 2',5'-oligoadenylate synthetase-like 11 2,5-oligoadenylate synthetase-like 11 2-5A synthase 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5 F\|5 60.64 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_030254512.1	XP_030110372.1	2'-5'-oligoadenylate synthase 2 isoform X1
NM_001347448.1	NP_001334377.1	2'-5'-oligoadenylate synthase 2 isoform 1
XM_017320884.1	XP_017176373.1	2'-5'-oligoadenylate synthase 2 isoform X2
NM_145227.3	NP_660262.2	2'-5'-oligoadenylate synthase 2 isoform 2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	OAS2	NP_001041599.1
Homo sapiens (human)	OAS2	NP_058197.2
Pan troglodytes (chimpanzee)	OAS2	XP_001151534.1
	OAS2	XP_001110954.1
Bos taurus (cattle)	OAS2	NP_001019728.1
Mus musculus (house mouse)	Oas2	NP_660262.2
Rattus norvegicus (Norway rat)	Oas2	NP_001009715.1

Gene Ontology
Bibliography

Related articles in PubMed

A mutation in the viral sensor 2'-5'-oligoadenylate synthetase 2 causes failure of lactation.
Oakes SR, Gallego-Ortega D, Stanford PM, Junankar S, Au WWY, Kikhtyak Z, von Korff A, Sergio CM, Law AMK, Castillo LE, Allerdice SL, Young AIJ, Piggin C, Whittle B, Bertram E, Naylor MJ, Roden DL, Donovan J, Korennykh A, Goodnow CC, O'Bryan MK, Ormandy CJ
PLoS genetics13(11)e1007072(2017 Nov)

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Liu X, Jiao Y, Cao Y, Deng N, Ma Y, Hasty KA, Kang A, Chen H, Stuart JM, Gu W
BMC immunology17(1)25(2016 08)

The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.
Mannion NM, Greenwood SM, Young R, Cox S, Brindle J, Read D, Nell?ker C, Vesely C, Ponting CP, McLaughlin PJ, Jantsch MF, Dorin J, Adams IR, Scadden AD, Ohman M, Keegan LP, O'Connell MA
Cell reports9(4)1482-94(2014 Nov)

Impact of lactobacilli on orally acquired listeriosis.
Archambaud C, Nahori MA, Soubigou G, B?cavin C, Laval L, Lechat P, Smokvina T, Langella P, Lecuit M, Cossart P
Proceedings of the National Academy of Sciences of the United States of America109(41)16684-9(2012 Oct)

The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities.
Kristiansen H, Gad HH, Eskildsen-Larsen S, Despres P, Hartmann R
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research31(1)41-7(2011 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

A non-synonymous mutation in Oas2 (I405N) in the viral sensor Oas2 was found and the mutation caused post-partum failure of lactation in healthy mice with otherwise normally developed mammary glands, characterized by greatly reduced milk protein synthesis coupled with epithelial cell death, inhibition of proliferation and a robust interferon response. The mutation activates the OAS2 pathway.
Title: A mutation in the viral sensor 2'-5'-oligoadenylate synthetase 2 causes failure of lactation.

The following Oas2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Oas2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu88911	XM_030254512.1 Latest version!	Mus musculus 2'-5' oligoadenylate synthetase 2 (Oas2), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu11421	NM_145227.3 Latest version!	Mus musculus 2'-5' oligoadenylate synthetase 2 (Oas2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$391.30 $559.00
OMu35889	NM_001347448.1 Latest version!	Mus musculus 2'-5' oligoadenylate synthetase 2 (Oas2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$391.30 $559.00
OMu81376	XM_017320884.1 Latest version!	Mus musculus 2'-5' oligoadenylate synthetase 2 (Oas2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Oas2 ( XM_030254512.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030110372.1 Mus musculus 2'-5' oligoadenylate synthetase 2 (Oas2), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OMu88911
Clone ID Related Accession (Same CDS sequence)	XM_030254512.1
Accession Version	XM_030254512.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1383bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	2'-5'-oligoadenylate synthase 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCACAAG GCGTCAGGAC CGTGCTGCGA CTTATCCAGC GGCCGACAGA GCTGTGTGTC 
TACTGGACAG TCAATTACAA CTTTGAGGAT GAGACAGTCC GGAACATCCT TCTGCACCAG 
CTCAGGTCCC AAAGACCAGT CATCTTGGAT CCAACTGACC CAACCAATAA TGTGGGCAAA 
GATGATGGGT TCTGGGAGCT ACTGACAGAG GAAGCTATGG CCTGGCTGTA CTCTCCCAGC 
CTGAATACTG AGTCACCTGC ACCATATTGG GATGTTCTGC CCATGCCACT TTTCGTCACT 
CCAAGCCACT TACTGAACAA GTTCATCAAG GACTTTCTCC AGCCCAACAA GCTCTTCCTA 
AAGCAGATCA AGGAAGCTGT TGACATTATA TGTTCCTTCC TTAAAAATGT CTGCTTCTTG 
AATTCTGACA CCAAAGTCCT GAAGACCGTC AAGGGAGGAT CCACTGCCAA AGGCACAGCT 
CTGAAGCGGG GATCAGATGC TGACATTGTT GTGTTCCTCT CCTCGCTGGA GAGTTACGAC 
TCTCTAAAAA CCAACCGCTC CCAGTTCGTC CAGGAGATCC AGAAGCAGTT AGAAGAATTC 
GTGCAGGCGC AGGAGTGGGA GGTGACGTTT GAGATTTCAA AATGGAAGGC TCCCAGAGTG 
CTGAGTTTTA CCTTGAAATC CAAGACTCTC AATGAAAGTG TCGAGTTCGA TGTCCTTCCC 
GCCTATGATG CACTAGGTCA ACTGCGGTCT GACTTCACCC TCAGGCCCGA AGCCTACAAG 
GATCTCATTG AGCTGTGTGC ATCACAGGAC ATCAAAGAAG GAGAGTTTTC TATCTGTTTT 
ACTGAGCTGC AGAGAAACTT CATTCAAACC CGGCCCACCA AACTGAAGAG TCTACTCCGC 
CTGATCAAGC ACTGGTACAA ACAGTATGAA AGGAAGATGA AGCCAAAAGC ATCTTTACCC 
CCAAAGTACG CCCTGGAGCT GCTCACCGTG TATGCCTGGG AGCAGGGCAG TGGCACAGAT 
GACTTTGACA TTGCTGAAGG CTTCCGGACC GTCCTGGACC TGGTTATAAA ATACCGGCAG 
CTCTGCATCT TCTGGACAGT CAATTACAAC TTTGAAGAGG AATACATGCG GAAGTTCCTA 
CTGACCCAGA TCCAGAAAAA GAGGCCTGTA ATCCTGGATC CAGCAGATCC CACAGGCGAT 
GTGGGAGGAG GTGACCGCTG GTGCTGGCAT CTTCTAGCTG AAGAAGCGAA GGAGTGGCTG 
TCCTCCCCTT GTTTCCAAGT GGAGCAAAAA GGCCTGGTAC AGCCTTGGAA AGTGCCAGTA 
ATGCAGACCC CCGGAAGCTG TGGAGGTCAG ATCTACCCCA CTGTGGGTGG AGTTACTAAG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030110372.1
CDS	1155..2537
Translation	MAQGVRTVLRLIQRPTELCVYWTVNYNFEDETVRNILLHQLRSQRPVILDPTDPTNNVGKDDGFWELLTEEAMAWLYSPSLNTESPAPYWDVLPMPLFVTPSHLLNKFIKDFLQPNKLFLKQIKEAVDIICSFLKNVCFLNSDTKVLKTVKGGSTAKGTALKRGSDADIVVFLSSLESYDSLKTNRSQFVQEIQKQLEEFVQAQEWEVTFEISKWKAPRVLSFTLKSKTLNESVEFDVLPAYDALGQLRSDFTLRPEAYKDLIELCASQDIKEGEFSICFTELQRNFIQTRPTKLKSLLRLIKHWYKQYERKMKPKASLPPKYALELLTVYAWEQGSGTDDFDIAEGFRTVLDLVIKYRQLCIFWTVNYNFEEEYMRKFLLTQIQKKRPVILDPADPTGDVGGGDRWCWHLLAEEAKEWLSSPCFQVEQKGLVQPWKVPVMQTPGSCGGQIYPTVGGVTK

Target ORF information:

RefSeq Version	XM_030254512.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus 2'-5' oligoadenylate synthetase 2 (Oas2), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030254512.1

ORF Insert Sequence:

ATGGCACAAG GCGTCAGGAC CGTGCTGCGA CTTATCCAGC GGCCGACAGA GCTGTGTGTC 
TACTGGACAG TCAATTACAA CTTTGAGGAT GAGACAGTCC GGAACATCCT TCTGCACCAG 
CTCAGGTCCC AAAGACCAGT CATCTTGGAT CCAACTGACC CAACCAATAA TGTGGGCAAA 
GATGATGGGT TCTGGGAGCT ACTGACAGAG GAAGCTATGG CCTGGCTGTA CTCTCCCAGC 
CTGAATACTG AGTCACCTGC ACCATATTGG GATGTTCTGC CCATGCCACT TTTCGTCACT 
CCAAGCCACT TACTGAACAA GTTCATCAAG GACTTTCTCC AGCCCAACAA GCTCTTCCTA 
AAGCAGATCA AGGAAGCTGT TGACATTATA TGTTCCTTCC TTAAAAATGT CTGCTTCTTG 
AATTCTGACA CCAAAGTCCT GAAGACCGTC AAGGGAGGAT CCACTGCCAA AGGCACAGCT 
CTGAAGCGGG GATCAGATGC TGACATTGTT GTGTTCCTCT CCTCGCTGGA GAGTTACGAC 
TCTCTAAAAA CCAACCGCTC CCAGTTCGTC CAGGAGATCC AGAAGCAGTT AGAAGAATTC 
GTGCAGGCGC AGGAGTGGGA GGTGACGTTT GAGATTTCAA AATGGAAGGC TCCCAGAGTG 
CTGAGTTTTA CCTTGAAATC CAAGACTCTC AATGAAAGTG TCGAGTTCGA TGTCCTTCCC 
GCCTATGATG CACTAGGTCA ACTGCGGTCT GACTTCACCC TCAGGCCCGA AGCCTACAAG 
GATCTCATTG AGCTGTGTGC ATCACAGGAC ATCAAAGAAG GAGAGTTTTC TATCTGTTTT 
ACTGAGCTGC AGAGAAACTT CATTCAAACC CGGCCCACCA AACTGAAGAG TCTACTCCGC 
CTGATCAAGC ACTGGTACAA ACAGTATGAA AGGAAGATGA AGCCAAAAGC ATCTTTACCC 
CCAAAGTACG CCCTGGAGCT GCTCACCGTG TATGCCTGGG AGCAGGGCAG TGGCACAGAT 
GACTTTGACA TTGCTGAAGG CTTCCGGACC GTCCTGGACC TGGTTATAAA ATACCGGCAG 
CTCTGCATCT TCTGGACAGT CAATTACAAC TTTGAAGAGG AATACATGCG GAAGTTCCTA 
CTGACCCAGA TCCAGAAAAA GAGGCCTGTA ATCCTGGATC CAGCAGATCC CACAGGCGAT 
GTGGGAGGAG GTGACCGCTG GTGCTGGCAT CTTCTAGCTG AAGAAGCGAA GGAGTGGCTG 
TCCTCCCCTT GTTTCCAAGT GGAGCAAAAA GGCCTGGTAC AGCCTTGGAA AGTGCCAGTA 
ATGCAGACCC CCGGAAGCTG TGGAGGTCAG ATCTACCCCA CTGTGGGTGG AGTTACTAAG 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Oas2 ( NM_145227.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_660262.2 Mus musculus 2'-5' oligoadenylate synthetase 2 (Oas2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu11421
Clone ID Related Accession (Same CDS sequence)	NM_145227.3
Accession Version	NM_145227.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2229bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-14
Organism	Mus musculus(house mouse)
Product	2'-5'-oligoadenylate synthase 2 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU694306.1, AB067535.1 and BC118538.1. On May 7, 2009 this sequence version replaced NM_145227.2. Transcript Variant: This variant (2) lacks an alternate coding exon in the 3' end compared to variant 1, that causes a frameshift. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB067535.1, BC118538.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAAACT GGCTGACTGG AAACTGGTCA TCTGACAGGT CATCTGGCTA TTCATCTGGC 
TGGTCACCTG GTGGGTCTTC AGGGGTGCCC TCCGGGCCAG TGCACAAGTT AGAAAAGTCT 
ATCCAGGCAA ACCTCACACC CAACGAAAAC TGTCTGAAGC AGATTGCGGT GTCCTCGGTG 
CCATCGCAGA AGCTAGAAGG GTATATCCAG GAAAACCTCA AACCTAACAG AGAATCTCTG 
AAGCAGATAG ACCAGGCCGT GGATGCCATC TGGGACCTGC TGCGCAGTCA GATCCCTGTG 
AAGGAAGTGG CTAAGGGTGG CTCCTATGGC CGGGAAACAG CCCTAAGAGG CTGCTCCGAT 
GGTACCCTTG TTCTCTTCAT GGACTGCTTC CAACAGTTCC AGGATCAGAT AAAATACCAA 
GATGCATACC TTGACGTCAT TGAACTGTGG CTGAAAATCC ATGAGAAGAA GTCAGTAAAG 
CATGAACATG CCCTTGTAGT ACAAGTGTCT GTACCAGGGC AGAGAATACT CCTGCAATTA 
CTTCCAGTCT TCAATCCTCT ACGCTCCAAT GAGAATCCCA GCTCCTGTGT CTATGTGGAT 
CTCAAAAAAT CCATGGATCA AGTAAGAGCC TCACCAGGGG AGTTCTCAGA CTGCTTCACC 
ACACTGCAGC AGCGGTTTTT CAAGAAATAT CCCCAAAGAC TGAAGGATTT GATCCTATTG 
GTCAAGCACT GGTATGAACA GTGCCAGGAG AAGTGGAAAA CACCCCCACC TCAGCCATTG 
CTGTACGCAC TGGAACTGCT CACTGTGTAT GCCTGGGAAC AGGGCTGCCA AGCTGAAGAC 
TTCGACATGG CACAAGGCGT CAGGACCGTG CTGCGACTTA TCCAGCGGCC GACAGAGCTG 
TGTGTCTACT GGACAGTCAA TTACAACTTT GAGGATGAGA CAGTCCGGAA CATCCTTCTG 
CACCAGCTCA GGTCCCAAAG ACCAGTCATC TTGGATCCAA CTGACCCAAC CAATAATGTG 
GGCAAAGATG ATGGGTTCTG GGAGCTACTG ACAGAGGAAG CTATGGCCTG GCTGTACTCT 
CCCAGCCTGA ATACTGAGTC ACCTGCACCA TATTGGGATG TTCTGCCCAT GCCACTTTTC 
GTCACTCCAA GCCACTTACT GAACAAGTTC ATCAAGGACT TTCTCCAGCC CAACAAGCTC 
TTCCTAAAGC AGATCAAGGA AGCTGTTGAC ATTATATGTT CCTTCCTTAA AAATGTCTGC 
TTCTTGAATT CTGACACCAA AGTCCTGAAG ACCGTCAAGG GAGGATCCAC TGCCAAAGGC 
ACAGCTCTGA AGCGGGGATC AGATGCTGAC ATTGTTGTGT TCCTCTCCTC GCTGGAGAGT 
TACGACTCTC TAAAAACCAA CCGCTCCCAG TTCGTCCAGG AGATCCAGAA GCAGTTAGAA 
GAATTCGTGC AGGCGCAGGA GTGGGAGGTG ACGTTTGAGA TTTCAAAATG GAAGGCTCCC 
AGAGTGCTGA GTTTTACCTT GAAATCCAAG ACTCTCAATG AAAGTGTCGA GTTCGATGTC 
CTTCCCGCCT ATGATGCACT AGGTCAACTG CGGTCTGACT TCACCCTCAG GCCCGAAGCC 
TACAAGGATC TCATTGAGCT GTGTGCATCA CAGGACATCA AAGAAGGAGA GTTTTCTATC 
TGTTTTACTG AGCTGCAGAG AAACTTCATT CAAACCCGGC CCACCAAACT GAAGAGTCTA 
CTCCGCCTGA TCAAGCACTG GTACAAACAG TATGAAAGGA AGATGAAGCC AAAAGCATCT 
TTACCCCCAA AGTACGCCCT GGAGCTGCTC ACCGTGTATG CCTGGGAGCA GGGCAGTGGC 
ACAGATGACT TTGACATTGC TGAAGGCTTC CGGACCGTCC TGGACCTGGT TATAAAATAC 
CGGCAGCTCT GCATCTTCTG GACAGTCAAT TACAACTTTG AAGAGGAATA CATGCGGAAG 
TTCCTACTGA CCCAGATCCA GAAAAAGAGG CCTGTAATCC TGGATCCAGC AGATCCCACA 
GGCGATGTGG GAGGAGGTGA CCGCTGGTGC TGGCATCTTC TAGCTGAAGA AGCGAAGGAG 
TGGCTGTCCT CCCCTTGTTT CCAAGTGGAG CAAAAAGGCC TGGTACAGCC TTGGAAAGTG 
CCAGTAATGC AGACCCCCGG AAGCTGTGGA GGTCAGATCT ACCCCACTGT GGGTGGAGTT 
ACTAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_660262.2
CDS	76..2304
Translation	MGNWLTGNWSSDRSSGYSSGWSPGGSSGVPSGPVHKLEKSIQANLTPNENCLKQIAVSSVPSQKLEGYIQENLKPNRESLKQIDQAVDAIWDLLRSQIPVKEVAKGGSYGRETALRGCSDGTLVLFMDCFQQFQDQIKYQDAYLDVIELWLKIHEKKSVKHEHALVVQVSVPGQRILLQLLPVFNPLRSNENPSSCVYVDLKKSMDQVRASPGEFSDCFTTLQQRFFKKYPQRLKDLILLVKHWYEQCQEKWKTPPPQPLLYALELLTVYAWEQGCQAEDFDMAQGVRTVLRLIQRPTELCVYWTVNYNFEDETVRNILLHQLRSQRPVILDPTDPTNNVGKDDGFWELLTEEAMAWLYSPSLNTESPAPYWDVLPMPLFVTPSHLLNKFIKDFLQPNKLFLKQIKEAVDIICSFLKNVCFLNSDTKVLKTVKGGSTAKGTALKRGSDADIVVFLSSLESYDSLKTNRSQFVQEIQKQLEEFVQAQEWEVTFEISKWKAPRVLSFTLKSKTLNESVEFDVLPAYDALGQLRSDFTLRPEAYKDLIELCASQDIKEGEFSICFTELQRNFIQTRPTKLKSLLRLIKHWYKQYERKMKPKASLPPKYALELLTVYAWEQGSGTDDFDIAEGFRTVLDLVIKYRQLCIFWTVNYNFEEEYMRKFLLTQIQKKRPVILDPADPTGDVGGGDRWCWHLLAEEAKEWLSSPCFQVEQKGLVQPWKVPVMQTPGSCGGQIYPTVGGVTK

Target ORF information:

RefSeq Version	NM_145227.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus 2'-5' oligoadenylate synthetase 2 (Oas2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145227.3

ORF Insert Sequence:

ATGGGAAACT GGCTGACTGG AAACTGGTCA TCTGACAGGT CATCTGGCTA TTCATCTGGC 
TGGTCACCTG GTGGGTCTTC AGGGGTGCCC TCCGGGCCAG TGCACAAGTT AGAAAAGTCT 
ATCCAGGCAA ACCTCACACC CAACGAAAAC TGTCTGAAGC AGATTGCGGT GTCCTCGGTG 
CCATCGCAGA AGCTAGAAGG GTATATCCAG GAAAACCTCA AACCTAACAG AGAATCTCTG 
AAGCAGATAG ACCAGGCCGT GGATGCCATC TGGGACCTGC TGCGCAGTCA GATCCCTGTG 
AAGGAAGTGG CTAAGGGTGG CTCCTATGGC CGGGAAACAG CCCTAAGAGG CTGCTCCGAT 
GGTACCCTTG TTCTCTTCAT GGACTGCTTC CAACAGTTCC AGGATCAGAT AAAATACCAA 
GATGCATACC TTGACGTCAT TGAACTGTGG CTGAAAATCC ATGAGAAGAA GTCAGTAAAG 
CATGAACATG CCCTTGTAGT ACAAGTGTCT GTACCAGGGC AGAGAATACT CCTGCAATTA 
CTTCCAGTCT TCAATCCTCT ACGCTCCAAT GAGAATCCCA GCTCCTGTGT CTATGTGGAT 
CTCAAAAAAT CCATGGATCA AGTAAGAGCC TCACCAGGGG AGTTCTCAGA CTGCTTCACC 
ACACTGCAGC AGCGGTTTTT CAAGAAATAT CCCCAAAGAC TGAAGGATTT GATCCTATTG 
GTCAAGCACT GGTATGAACA GTGCCAGGAG AAGTGGAAAA CACCCCCACC TCAGCCATTG 
CTGTACGCAC TGGAACTGCT CACTGTGTAT GCCTGGGAAC AGGGCTGCCA AGCTGAAGAC 
TTCGACATGG CACAAGGCGT CAGGACCGTG CTGCGACTTA TCCAGCGGCC GACAGAGCTG 
TGTGTCTACT GGACAGTCAA TTACAACTTT GAGGATGAGA CAGTCCGGAA CATCCTTCTG 
CACCAGCTCA GGTCCCAAAG ACCAGTCATC TTGGATCCAA CTGACCCAAC CAATAATGTG 
GGCAAAGATG ATGGGTTCTG GGAGCTACTG ACAGAGGAAG CTATGGCCTG GCTGTACTCT 
CCCAGCCTGA ATACTGAGTC ACCTGCACCA TATTGGGATG TTCTGCCCAT GCCACTTTTC 
GTCACTCCAA GCCACTTACT GAACAAGTTC ATCAAGGACT TTCTCCAGCC CAACAAGCTC 
TTCCTAAAGC AGATCAAGGA AGCTGTTGAC ATTATATGTT CCTTCCTTAA AAATGTCTGC 
TTCTTGAATT CTGACACCAA AGTCCTGAAG ACCGTCAAGG GAGGATCCAC TGCCAAAGGC 
ACAGCTCTGA AGCGGGGATC AGATGCTGAC ATTGTTGTGT TCCTCTCCTC GCTGGAGAGT 
TACGACTCTC TAAAAACCAA CCGCTCCCAG TTCGTCCAGG AGATCCAGAA GCAGTTAGAA 
GAATTCGTGC AGGCGCAGGA GTGGGAGGTG ACGTTTGAGA TTTCAAAATG GAAGGCTCCC 
AGAGTGCTGA GTTTTACCTT GAAATCCAAG ACTCTCAATG AAAGTGTCGA GTTCGATGTC 
CTTCCCGCCT ATGATGCACT AGGTCAACTG CGGTCTGACT TCACCCTCAG GCCCGAAGCC 
TACAAGGATC TCATTGAGCT GTGTGCATCA CAGGACATCA AAGAAGGAGA GTTTTCTATC 
TGTTTTACTG AGCTGCAGAG AAACTTCATT CAAACCCGGC CCACCAAACT GAAGAGTCTA 
CTCCGCCTGA TCAAGCACTG GTACAAACAG TATGAAAGGA AGATGAAGCC AAAAGCATCT 
TTACCCCCAA AGTACGCCCT GGAGCTGCTC ACCGTGTATG CCTGGGAGCA GGGCAGTGGC 
ACAGATGACT TTGACATTGC TGAAGGCTTC CGGACCGTCC TGGACCTGGT TATAAAATAC 
CGGCAGCTCT GCATCTTCTG GACAGTCAAT TACAACTTTG AAGAGGAATA CATGCGGAAG 
TTCCTACTGA CCCAGATCCA GAAAAAGAGG CCTGTAATCC TGGATCCAGC AGATCCCACA 
GGCGATGTGG GAGGAGGTGA CCGCTGGTGC TGGCATCTTC TAGCTGAAGA AGCGAAGGAG 
TGGCTGTCCT CCCCTTGTTT CCAAGTGGAG CAAAAAGGCC TGGTACAGCC TTGGAAAGTG 
CCAGTAATGC AGACCCCCGG AAGCTGTGGA GGTCAGATCT ACCCCACTGT GGGTGGAGTT 
ACTAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Oas2 ( NM_001347448.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001334377.1 Mus musculus 2'-5' oligoadenylate synthetase 2 (Oas2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu35889
Clone ID Related Accession (Same CDS sequence)	NM_001347448.1
Accession Version	NM_001347448.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2256bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Mus musculus(house mouse)
Product	2'-5'-oligoadenylate synthase 2 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC115937.14. On Nov 29, 2016 this sequence version replaced XM_006530325.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF418010.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAAACT GGCTGACTGG AAACTGGTCA TCTGACAGGT CATCTGGCTA TTCATCTGGC 
TGGTCACCTG GTGGGTCTTC AGGGGTGCCC TCCGGGCCAG TGCACAAGTT AGAAAAGTCT 
ATCCAGGCAA ACCTCACACC CAACGAAAAC TGTCTGAAGC AGATTGCGGT GTCCTCGGTG 
CCATCGCAGA AGCTAGAAGG GTATATCCAG GAAAACCTCA AACCTAACAG AGAATCTCTG 
AAGCAGATAG ACCAGGCCGT GGATGCCATC TGGGACCTGC TGCGCAGTCA GATCCCTGTG 
AAGGAAGTGG CTAAGGGTGG CTCCTATGGC CGGGAAACAG CCCTAAGAGG CTGCTCCGAT 
GGTACCCTTG TTCTCTTCAT GGACTGCTTC CAACAGTTCC AGGATCAGAT AAAATACCAA 
GATGCATACC TTGACGTCAT TGAACTGTGG CTGAAAATCC ATGAGAAGAA GTCAGTAAAG 
CATGAACATG CCCTTGTAGT ACAAGTGTCT GTACCAGGGC AGAGAATACT CCTGCAATTA 
CTTCCAGTCT TCAATCCTCT ACGCTCCAAT GAGAATCCCA GCTCCTGTGT CTATGTGGAT 
CTCAAAAAAT CCATGGATCA AGTAAGAGCC TCACCAGGGG AGTTCTCAGA CTGCTTCACC 
ACACTGCAGC AGCGGTTTTT CAAGAAATAT CCCCAAAGAC TGAAGGATTT GATCCTATTG 
GTCAAGCACT GGTATGAACA GTGCCAGGAG AAGTGGAAAA CACCCCCACC TCAGCCATTG 
CTGTACGCAC TGGAACTGCT CACTGTGTAT GCCTGGGAAC AGGGCTGCCA AGCTGAAGAC 
TTCGACATGG CACAAGGCGT CAGGACCGTG CTGCGACTTA TCCAGCGGCC GACAGAGCTG 
TGTGTCTACT GGACAGTCAA TTACAACTTT GAGGATGAGA CAGTCCGGAA CATCCTTCTG 
CACCAGCTCA GGTCCCAAAG ACCAGTCATC TTGGATCCAA CTGACCCAAC CAATAATGTG 
GGCAAAGATG ATGGGTTCTG GGAGCTACTG ACAGAGGAAG CTATGGCCTG GCTGTACTCT 
CCCAGCCTGA ATACTGAGTC ACCTGCACCA TATTGGGATG TTCTGCCCAT GCCACTTTTC 
GTCACTCCAA GCCACTTACT GAACAAGTTC ATCAAGGACT TTCTCCAGCC CAACAAGCTC 
TTCCTAAAGC AGATCAAGGA AGCTGTTGAC ATTATATGTT CCTTCCTTAA AAATGTCTGC 
TTCTTGAATT CTGACACCAA AGTCCTGAAG ACCGTCAAGG GAGGATCCAC TGCCAAAGGC 
ACAGCTCTGA AGCGGGGATC AGATGCTGAC ATTGTTGTGT TCCTCTCCTC GCTGGAGAGT 
TACGACTCTC TAAAAACCAA CCGCTCCCAG TTCGTCCAGG AGATCCAGAA GCAGTTAGAA 
GAATTCGTGC AGGCGCAGGA GTGGGAGGTG ACGTTTGAGA TTTCAAAATG GAAGGCTCCC 
AGAGTGCTGA GTTTTACCTT GAAATCCAAG ACTCTCAATG AAAGTGTCGA GTTCGATGTC 
CTTCCCGCCT ATGATGCACT AGGTCAACTG CGGTCTGACT TCACCCTCAG GCCCGAAGCC 
TACAAGGATC TCATTGAGCT GTGTGCATCA CAGGACATCA AAGAAGGAGA GTTTTCTATC 
TGTTTTACTG AGCTGCAGAG AAACTTCATT CAAACCCGGC CCACCAAACT GAAGAGTCTA 
CTCCGCCTGA TCAAGCACTG GTACAAACAG TATGAAAGGA AGATGAAGCC AAAAGCATCT 
TTACCCCCAA AGTACGCCCT GGAGCTGCTC ACCGTGTATG CCTGGGAGCA GGGCAGTGGC 
ACAGATGACT TTGACATTGC TGAAGGCTTC CGGACCGTCC TGGACCTGGT TATAAAATAC 
CGGCAGCTCT GCATCTTCTG GACAGTCAAT TACAACTTTG AAGAGGAATA CATGCGGAAG 
TTCCTACTGA CCCAGATCCA GAAAAAGAGG CCTGTAATCC TGGATCCAGC AGATCCCACA 
GGCGATGTGG GAGGAGGTGA CCGCTGGTGC TGGCATCTTC TAGCTGAAGA AGCGAAGGAG 
TGGCTGTCCT CCCCTTGTTT CCAAGTGGAG CAAAAAGGCC TGGTACAGCC TTGGAAAGTG 
CCAGTACCTA GAGATCTAAA GACAAGTGAC ATGGTGGGAG TGTTCACTAC AGGAGGGATC 
TTGTGGCAGG ACCAAGGCTT TTTGTCATTT GTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001334377.1
CDS	76..2331
Translation	MGNWLTGNWSSDRSSGYSSGWSPGGSSGVPSGPVHKLEKSIQANLTPNENCLKQIAVSSVPSQKLEGYIQENLKPNRESLKQIDQAVDAIWDLLRSQIPVKEVAKGGSYGRETALRGCSDGTLVLFMDCFQQFQDQIKYQDAYLDVIELWLKIHEKKSVKHEHALVVQVSVPGQRILLQLLPVFNPLRSNENPSSCVYVDLKKSMDQVRASPGEFSDCFTTLQQRFFKKYPQRLKDLILLVKHWYEQCQEKWKTPPPQPLLYALELLTVYAWEQGCQAEDFDMAQGVRTVLRLIQRPTELCVYWTVNYNFEDETVRNILLHQLRSQRPVILDPTDPTNNVGKDDGFWELLTEEAMAWLYSPSLNTESPAPYWDVLPMPLFVTPSHLLNKFIKDFLQPNKLFLKQIKEAVDIICSFLKNVCFLNSDTKVLKTVKGGSTAKGTALKRGSDADIVVFLSSLESYDSLKTNRSQFVQEIQKQLEEFVQAQEWEVTFEISKWKAPRVLSFTLKSKTLNESVEFDVLPAYDALGQLRSDFTLRPEAYKDLIELCASQDIKEGEFSICFTELQRNFIQTRPTKLKSLLRLIKHWYKQYERKMKPKASLPPKYALELLTVYAWEQGSGTDDFDIAEGFRTVLDLVIKYRQLCIFWTVNYNFEEEYMRKFLLTQIQKKRPVILDPADPTGDVGGGDRWCWHLLAEEAKEWLSSPCFQVEQKGLVQPWKVPVPRDLKTSDMVGVFTTGGILWQDQGFLSFV

Target ORF information:

RefSeq Version	NM_001347448.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus 2'-5' oligoadenylate synthetase 2 (Oas2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001347448.1

ORF Insert Sequence:

ATGGGAAACT GGCTGACTGG AAACTGGTCA TCTGACAGGT CATCTGGCTA TTCATCTGGC 
TGGTCACCTG GTGGGTCTTC AGGGGTGCCC TCCGGGCCAG TGCACAAGTT AGAAAAGTCT 
ATCCAGGCAA ACCTCACACC CAACGAAAAC TGTCTGAAGC AGATTGCGGT GTCCTCGGTG 
CCATCGCAGA AGCTAGAAGG GTATATCCAG GAAAACCTCA AACCTAACAG AGAATCTCTG 
AAGCAGATAG ACCAGGCCGT GGATGCCATC TGGGACCTGC TGCGCAGTCA GATCCCTGTG 
AAGGAAGTGG CTAAGGGTGG CTCCTATGGC CGGGAAACAG CCCTAAGAGG CTGCTCCGAT 
GGTACCCTTG TTCTCTTCAT GGACTGCTTC CAACAGTTCC AGGATCAGAT AAAATACCAA 
GATGCATACC TTGACGTCAT TGAACTGTGG CTGAAAATCC ATGAGAAGAA GTCAGTAAAG 
CATGAACATG CCCTTGTAGT ACAAGTGTCT GTACCAGGGC AGAGAATACT CCTGCAATTA 
CTTCCAGTCT TCAATCCTCT ACGCTCCAAT GAGAATCCCA GCTCCTGTGT CTATGTGGAT 
CTCAAAAAAT CCATGGATCA AGTAAGAGCC TCACCAGGGG AGTTCTCAGA CTGCTTCACC 
ACACTGCAGC AGCGGTTTTT CAAGAAATAT CCCCAAAGAC TGAAGGATTT GATCCTATTG 
GTCAAGCACT GGTATGAACA GTGCCAGGAG AAGTGGAAAA CACCCCCACC TCAGCCATTG 
CTGTACGCAC TGGAACTGCT CACTGTGTAT GCCTGGGAAC AGGGCTGCCA AGCTGAAGAC 
TTCGACATGG CACAAGGCGT CAGGACCGTG CTGCGACTTA TCCAGCGGCC GACAGAGCTG 
TGTGTCTACT GGACAGTCAA TTACAACTTT GAGGATGAGA CAGTCCGGAA CATCCTTCTG 
CACCAGCTCA GGTCCCAAAG ACCAGTCATC TTGGATCCAA CTGACCCAAC CAATAATGTG 
GGCAAAGATG ATGGGTTCTG GGAGCTACTG ACAGAGGAAG CTATGGCCTG GCTGTACTCT 
CCCAGCCTGA ATACTGAGTC ACCTGCACCA TATTGGGATG TTCTGCCCAT GCCACTTTTC 
GTCACTCCAA GCCACTTACT GAACAAGTTC ATCAAGGACT TTCTCCAGCC CAACAAGCTC 
TTCCTAAAGC AGATCAAGGA AGCTGTTGAC ATTATATGTT CCTTCCTTAA AAATGTCTGC 
TTCTTGAATT CTGACACCAA AGTCCTGAAG ACCGTCAAGG GAGGATCCAC TGCCAAAGGC 
ACAGCTCTGA AGCGGGGATC AGATGCTGAC ATTGTTGTGT TCCTCTCCTC GCTGGAGAGT 
TACGACTCTC TAAAAACCAA CCGCTCCCAG TTCGTCCAGG AGATCCAGAA GCAGTTAGAA 
GAATTCGTGC AGGCGCAGGA GTGGGAGGTG ACGTTTGAGA TTTCAAAATG GAAGGCTCCC 
AGAGTGCTGA GTTTTACCTT GAAATCCAAG ACTCTCAATG AAAGTGTCGA GTTCGATGTC 
CTTCCCGCCT ATGATGCACT AGGTCAACTG CGGTCTGACT TCACCCTCAG GCCCGAAGCC 
TACAAGGATC TCATTGAGCT GTGTGCATCA CAGGACATCA AAGAAGGAGA GTTTTCTATC 
TGTTTTACTG AGCTGCAGAG AAACTTCATT CAAACCCGGC CCACCAAACT GAAGAGTCTA 
CTCCGCCTGA TCAAGCACTG GTACAAACAG TATGAAAGGA AGATGAAGCC AAAAGCATCT 
TTACCCCCAA AGTACGCCCT GGAGCTGCTC ACCGTGTATG CCTGGGAGCA GGGCAGTGGC 
ACAGATGACT TTGACATTGC TGAAGGCTTC CGGACCGTCC TGGACCTGGT TATAAAATAC 
CGGCAGCTCT GCATCTTCTG GACAGTCAAT TACAACTTTG AAGAGGAATA CATGCGGAAG 
TTCCTACTGA CCCAGATCCA GAAAAAGAGG CCTGTAATCC TGGATCCAGC AGATCCCACA 
GGCGATGTGG GAGGAGGTGA CCGCTGGTGC TGGCATCTTC TAGCTGAAGA AGCGAAGGAG 
TGGCTGTCCT CCCCTTGTTT CCAAGTGGAG CAAAAAGGCC TGGTACAGCC TTGGAAAGTG 
CCAGTACCTA GAGATCTAAA GACAAGTGAC ATGGTGGGAG TGTTCACTAC AGGAGGGATC 
TTGTGGCAGG ACCAAGGCTT TTTGTCATTT GTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Oas2 ( XM_017320884.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017176373.1 Mus musculus 2'-5' oligoadenylate synthetase 2 (Oas2), transcript variant X3, mRNA.

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CloneID	OMu81376
Clone ID Related Accession (Same CDS sequence)	XM_017320884.1
Accession Version	XM_017320884.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1593bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	2'-5'-oligoadenylate synthase 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAAACT GGCTGACTGG AAACTGGTCA TCTGACAGGT CATCTGGCTA TTCATCTGGC 
TGGTCACCTG GTGGGTCTTC AGGGGTGCCC TCCGGGCCAG TGCACAAGTT AGAAAAGTCT 
ATCCAGGCAA ACCTCACACC CAACGAAAAC TGTCTGAAGC AGATTGCGGT GTCCTCGGTG 
CCATCGCAGA AGCTAGAAGG GTATATCCAG GAAAACCTCA AACCTAACAG AGAATCTCTG 
AAGCAGATAG ACCAGGCCGT GGATGCCATC TGGGACCTGC TGCGCAGTCA GATCCCTGTG 
AAGGAAGTGG CTAAGGGTGG CTCCTATGGC CGGGAAACAG CCCTAAGAGG CTGCTCCGAT 
GGTACCCTTG TTCTCTTCAT GGACTGCTTC CAACAGTTCC AGGATCAGAT AAAATACCAA 
GATGCATACC TTGACGTCAT TGAACTGTGG CTGAAAATCC ATGAGAAGAA GTCAGTAAAG 
CATGAACATG CCCTTGTAGT ACAAGTGTCT GTACCAGGGC AGAGAATACT CCTGCAATTA 
CTTCCAGTCT TCAATCCTCT ACGCTCCAAT GAGAATCCCA GCTCCTGTGT CTATGTGGAT 
CTCAAAAAAT CCATGGATCA AGTAAGAGCC TCACCAGGGG AGTTCTCAGA CTGCTTCACC 
ACACTGCAGC AGCGGTTTTT CAAGAAATAT CCCCAAAGAC TGAAGGATTT GATCCTATTG 
GTCAAGCACT GGTATGAACA GTGCCAGGAG AAGTGGAAAA CACCCCCACC TCAGCCATTG 
CTGTACGCAC TGGAACTGCT CACTGTGTAT GCCTGGGAAC AGGGCTGCCA AGCTGAAGAC 
TTCGACATGG CACAAGGCGT CAGGACCGTG CTGCGACTTA TCCAGCGGCC GACAGAGCTG 
TGTGTCTACT GGACAGTCAA TTACAACTTT GAGGATGAGA CAGTCCGGAA CATCCTTCTG 
CACCAGCTCA GGTCCCAAAG ACCAGTCATC TTGGATCCAA CTGACCCAAC CAATAATGTG 
GGCAAAGATG ATGGGTTCTG GGAGCTACTG ACAGAGGAAG CTATGGCCTG GCTGTACTCT 
CCCAGCCTGA ATACTGAGTC ACCTGCACCA TATTGGGATG TTCTGCCCAT GCCACTTTTC 
GTCACTCCAA GCCACTTACT GAACAAGTTC ATCAAGGACT TTCTCCAGCC CAACAAGCTC 
TTCCTAAAGC AGATCAAGGA AGCTGTTGAC ATTATATGTT CCTTCCTTAA AAATGTCTGC 
TTCTTGAATT CTGACACCAA AGTCCTGAAG ACCGTCAAGG GAGGATCCAC TGCCAAAGGC 
ACAGCTCTGA AGCGGGGATC AGATGCTGAC ATTGTTGTGT TCCTCTCCTC GCTGGAGAGT 
TACGACTCTC TAAAAACCAA CCGCTCCCAG TTCGTCCAGG AGATCCAGAA GCAGTTAGAA 
GAATTCGTGC AGGCGCAGGA GTGGGAGGTG ACGTTTGAGA TTTCAAAATG GAAGGCTCCC 
AGAGTGCTGA GTTTTACCTT GAAATCCAAG ACTCTCAATG AAAGTGTCGA GTTCGATGTC 
CTTCCCGCCT ATGATGCACT AGGGTGGAGA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017176373.1
CDS	102..1694
Translation	MGNWLTGNWSSDRSSGYSSGWSPGGSSGVPSGPVHKLEKSIQANLTPNENCLKQIAVSSVPSQKLEGYIQENLKPNRESLKQIDQAVDAIWDLLRSQIPVKEVAKGGSYGRETALRGCSDGTLVLFMDCFQQFQDQIKYQDAYLDVIELWLKIHEKKSVKHEHALVVQVSVPGQRILLQLLPVFNPLRSNENPSSCVYVDLKKSMDQVRASPGEFSDCFTTLQQRFFKKYPQRLKDLILLVKHWYEQCQEKWKTPPPQPLLYALELLTVYAWEQGCQAEDFDMAQGVRTVLRLIQRPTELCVYWTVNYNFEDETVRNILLHQLRSQRPVILDPTDPTNNVGKDDGFWELLTEEAMAWLYSPSLNTESPAPYWDVLPMPLFVTPSHLLNKFIKDFLQPNKLFLKQIKEAVDIICSFLKNVCFLNSDTKVLKTVKGGSTAKGTALKRGSDADIVVFLSSLESYDSLKTNRSQFVQEIQKQLEEFVQAQEWEVTFEISKWKAPRVLSFTLKSKTLNESVEFDVLPAYDALGWR

Target ORF information:

RefSeq Version	XM_017320884.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus 2'-5' oligoadenylate synthetase 2 (Oas2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017320884.1

ORF Insert Sequence:

ATGGGAAACT GGCTGACTGG AAACTGGTCA TCTGACAGGT CATCTGGCTA TTCATCTGGC 
TGGTCACCTG GTGGGTCTTC AGGGGTGCCC TCCGGGCCAG TGCACAAGTT AGAAAAGTCT 
ATCCAGGCAA ACCTCACACC CAACGAAAAC TGTCTGAAGC AGATTGCGGT GTCCTCGGTG 
CCATCGCAGA AGCTAGAAGG GTATATCCAG GAAAACCTCA AACCTAACAG AGAATCTCTG 
AAGCAGATAG ACCAGGCCGT GGATGCCATC TGGGACCTGC TGCGCAGTCA GATCCCTGTG 
AAGGAAGTGG CTAAGGGTGG CTCCTATGGC CGGGAAACAG CCCTAAGAGG CTGCTCCGAT 
GGTACCCTTG TTCTCTTCAT GGACTGCTTC CAACAGTTCC AGGATCAGAT AAAATACCAA 
GATGCATACC TTGACGTCAT TGAACTGTGG CTGAAAATCC ATGAGAAGAA GTCAGTAAAG 
CATGAACATG CCCTTGTAGT ACAAGTGTCT GTACCAGGGC AGAGAATACT CCTGCAATTA 
CTTCCAGTCT TCAATCCTCT ACGCTCCAAT GAGAATCCCA GCTCCTGTGT CTATGTGGAT 
CTCAAAAAAT CCATGGATCA AGTAAGAGCC TCACCAGGGG AGTTCTCAGA CTGCTTCACC 
ACACTGCAGC AGCGGTTTTT CAAGAAATAT CCCCAAAGAC TGAAGGATTT GATCCTATTG 
GTCAAGCACT GGTATGAACA GTGCCAGGAG AAGTGGAAAA CACCCCCACC TCAGCCATTG 
CTGTACGCAC TGGAACTGCT CACTGTGTAT GCCTGGGAAC AGGGCTGCCA AGCTGAAGAC 
TTCGACATGG CACAAGGCGT CAGGACCGTG CTGCGACTTA TCCAGCGGCC GACAGAGCTG 
TGTGTCTACT GGACAGTCAA TTACAACTTT GAGGATGAGA CAGTCCGGAA CATCCTTCTG 
CACCAGCTCA GGTCCCAAAG ACCAGTCATC TTGGATCCAA CTGACCCAAC CAATAATGTG 
GGCAAAGATG ATGGGTTCTG GGAGCTACTG ACAGAGGAAG CTATGGCCTG GCTGTACTCT 
CCCAGCCTGA ATACTGAGTC ACCTGCACCA TATTGGGATG TTCTGCCCAT GCCACTTTTC 
GTCACTCCAA GCCACTTACT GAACAAGTTC ATCAAGGACT TTCTCCAGCC CAACAAGCTC 
TTCCTAAAGC AGATCAAGGA AGCTGTTGAC ATTATATGTT CCTTCCTTAA AAATGTCTGC 
TTCTTGAATT CTGACACCAA AGTCCTGAAG ACCGTCAAGG GAGGATCCAC TGCCAAAGGC 
ACAGCTCTGA AGCGGGGATC AGATGCTGAC ATTGTTGTGT TCCTCTCCTC GCTGGAGAGT 
TACGACTCTC TAAAAACCAA CCGCTCCCAG TTCGTCCAGG AGATCCAGAA GCAGTTAGAA 
GAATTCGTGC AGGCGCAGGA GTGGGAGGTG ACGTTTGAGA TTTCAAAATG GAAGGCTCCC 
AGAGTGCTGA GTTTTACCTT GAAATCCAAG ACTCTCAATG AAAGTGTCGA GTTCGATGTC 
CTTCCCGCCT ATGATGCACT AGGGTGGAGA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A mutation in the viral sensor 2'-5'-oligoadenylate synthetase 2 causes failure of lactation.
PLoS genetics13(11)e1007072(2017 Nov)
Oakes SR,Gallego-Ortega D,Stanford PM,Junankar S,Au WWY,Kikhtyak Z,von Korff A,Sergio CM,Law AMK,Castillo LE,Allerdice SL,Young AIJ,Piggin C,Whittle B,Bertram E,Naylor MJ,Roden DL,Donovan J,Korennykh A,Goodnow CC,O'Bryan MK,Ormandy CJ

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
BMC immunology17(1)25(2016 08)
Liu X,Jiao Y,Cao Y,Deng N,Ma Y,Hasty KA,Kang A,Chen H,Stuart JM,Gu W

The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.
Cell reports9(4)1482-94(2014 Nov)
Mannion NM,Greenwood SM,Young R,Cox S,Brindle J,Read D,Nell?ker C,Vesely C,Ponting CP,McLaughlin PJ,Jantsch MF,Dorin J,Adams IR,Scadden AD,Ohman M,Keegan LP,O'Connell MA

Impact of lactobacilli on orally acquired listeriosis.
Proceedings of the National Academy of Sciences of the United States of America109(41)16684-9(2012 Oct)
Archambaud C,Nahori MA,Soubigou G,B?cavin C,Laval L,Lechat P,Smokvina T,Langella P,Lecuit M,Cossart P

The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research31(1)41-7(2011 Jan)
Kristiansen H,Gad HH,Eskildsen-Larsen S,Despres P,Hartmann R

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Oas2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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