Oas2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Oas2
Entrez Gene ID	363938
Full Name	2'-5' oligoadenylate synthetase 2
General protein information	Preferred Names 2'-5' oligoadenylate synthetase 2 Names 2'-5'-oligoadenylate synthase 2 (2-5')oligo(A) synthase 2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 2-5A synthase 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 12 Map Location: 12q16

mRNA and Protein(s)

mRNA	Protein	Name
NM_001009715.1	NP_001009715.1	2'-5'-oligoadenylate synthase 2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	OAS2	NP_001041599.1
Homo sapiens (human)	OAS2	NP_058197.2
Pan troglodytes (chimpanzee)	OAS2	XP_001151534.1
	OAS2	XP_001110954.1
Bos taurus (cattle)	OAS2	NP_001019728.1
Mus musculus (house mouse)	Oas2	NP_660262.2
Rattus norvegicus (Norway rat)	Oas2	NP_001009715.1

Gene Ontology
Bibliography

Related articles in PubMed

A mutation in the viral sensor 2'-5'-oligoadenylate synthetase 2 causes failure of lactation.
Oakes SR, Gallego-Ortega D, Stanford PM, Junankar S, Au WWY, Kikhtyak Z, von Korff A, Sergio CM, Law AMK, Castillo LE, Allerdice SL, Young AIJ, Piggin C, Whittle B, Bertram E, Naylor MJ, Roden DL, Donovan J, Korennykh A, Goodnow CC, O'Bryan MK, Ormandy CJ
PLoS genetics13(11)e1007072(2017 Nov)

Impact of lactobacilli on orally acquired listeriosis.
Archambaud C, Nahori MA, Soubigou G, B?cavin C, Laval L, Lechat P, Smokvina T, Langella P, Lecuit M, Cossart P
Proceedings of the National Academy of Sciences of the United States of America109(41)16684-9(2012 Oct)

Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)

Distinct antiviral roles for human 2',5'-oligoadenylate synthetase family members against dengue virus infection.
Lin RJ, Yu HP, Chang BL, Tang WC, Liao CL, Lin YL
Journal of immunology (Baltimore, Md. : 1950)183(12)8035-43(2009 Dec)

The mammalian 2'-5' oligoadenylate synthetase gene family: evidence for concerted evolution of paralogous Oas1 genes in Rodentia and Artiodactyla.
Perelygin AA, Zharkikh AA, Scherbik SV, Brinton MA
Journal of molecular evolution63(4)562-76(2006 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Oas2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Oas2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00972	NM_001009715.1 Latest version!	Rattus norvegicus 2'-5' oligoadenylate synthetase 2 (Oas2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Oas2 ( NM_001009715.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001009715.1 Rattus norvegicus 2'-5' oligoadenylate synthetase 2 (Oas2), mRNA.

Price & Availability↑

CloneID	ORa00972
Clone ID Related Accession (Same CDS sequence)	NM_001009715.1
Accession Version	NM_001009715.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2202bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-17
Organism	Rattus norvegicus(Norway rat)
Product	2'-5'-oligoadenylate synthase 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY230746.1. On Jan 13, 2005 this sequence version replaced XM_344120.1. ##Evidence-Data-START## Transcript exon combination :: AY230746.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689603, SAMN02642647 [ECO:0000348] ##Evidence-Data-END##

ATGGGAAACT GGATGCCTGG CTGGTCATCC AGTGGGTCTT TGGGGGTGCC CCCCATGCCA 
GTGCAGAAGC TAGAAAAGTC TGTCCAGGTA AACCTTGAAC CAGATGAAAA ATGTCTGAGT 
CAGACCGAGG TGTCCTCTGT ACCATCCCAG AAGCTAGAAG AATATATCCA GGCAAACCTC 
AAACCCGATG AAGAATCTCT GAAGCAGATA GACCAGGCTG TGGATGCCAT CTCTGACCTG 
CTGTGCAGTG AGGTGATGAT CGATGTGCTG AAAGTGGTTA AGGGTGGCTC CTATGGTCGG 
AAAACAGTCC TAAGAGACTG CTCCGATGGT ACACTTGTTC TCTTCACCGG TCTCTTCAAA 
CAGTTCCAAG ACCAGAAGAA ATACCAAGAT AAGCTCCTTG ACTTGATTGA ACAACGGCTG 
AAAAGCCATG AGAAATACAA GAAGTCAGTA AAACGTAAAC TTAGCCTCCT TGAAGTACAA 
GTGTCTATAC CAGGGCAGAG TATACTCTTG CAGTTGCTTC CAACCTTCAA TCCTCTGTGC 
ATCAGTGAGA ATCCCAGCGC CCAGGTCTAT CAGAATCTCA AAAGATCCAT GGATCAAGTA 
AAAGCATCAC CTGGGGAATT CTCAGACTGC TTCACCACAC TGCAGCAGAG GTTTTTCGAG 
AAATATCCCG GGAGACTGAA GGATTTGATT CTATTGGTCA AGCACTGGTA TAAACAGTTG 
CAGGATAAGT GGATAATACC CTCACCTCCG CCATTGCTAT ATGCACTGGA GCTGCTTACT 
GTGTATGCCT GGGAACAGGG CTGCCAGACT AAAGACTTTG ACATCACGCA AGGTATCAGG 
ACTGTGCTGC AACTCATCAG TCAGCCGACA AACCTGTGTG TCTACTGGTT AGACAATTAC 
AACTTTGAGG ATGAGACAGT CCGGAACAAC CTTCTGCACC AGCTCAACTC CCCAAGACCG 
GTCATCTTGG ATCCAACCGA CCCAACCAAC AATGTGGGCA AAGATGACAG GTTCTGGCAG 
CTACTGGCAG AAGAGGCTCA GGAGTGGCTG AACTCTCTCA GACTGAATAA GCCACACAAA 
CCATGTTGGG ATGTTCTGCC CATGCCATTT TTCATCACCC CAAGCCACTG CCTGGACAAG 
TTCATCAAAG ACTTCCTCCA ACCTGACAAG GTCTTCCTAA ACCAAATCAA AAGAGCTGTT 
GACATTATCT GTTCATTCTT AAAAGAGACC TGCTTCCAGA ATTCTGACAT CAAAGTCCTG 
AAGATCATCA AGGGAGGATC CACTGCCAAA GGCACAGCTC TGCAGCAGAG ATCAGATGCT 
GACATCATAG TGTTCCTCAG CTCACTGGAT AGTTATGACT CCCTAGAAAC TGAACGCTCC 
CAGTACGTCC AGGAGATCCG AAAGCAGTTA GAAGCCTGCC AGAAGGCCTT TAATTTAGGG 
GTGAAGTTTG ATATTTCCAA ATGGATGGCC CCCAGGGTGC TGAGTTTTAC CCTGGAATCC 
AAGAGTCTCA AGCAAAGTGT GGAGTTCGAT GTCCTTCCCG CCTATGATGC ACTAGGTCAG 
CTGCGGTCTG ACTACACCTC CAGGCTCAAA GCCTACAAGA AGCTCATTGA GCTGTATGCC 
TCACAGGACA GCCTCAAAGG AGGGGAGTTT TCAGTCTGTT TTACAGAGCT ACAGAGAGAC 
TTCATTGAAA CCAGGCCCAC CAAACTCAAG GGTCTGATCC GCCTGATCAA GCACTGGTAC 
AAACAGTGTG AAAGGAAGAT GAAGCCAAAA GCATCTTTGC CTCCAAAGTA CGCACTGGAG 
CTGCTCACCG TGTATGCGTG GGAGCATGGC AGTGGCACAG ATGGCTTCGA CACTGCTGAA 
GGCTTCCGGA CCGTCCTGGA CTTGGTCATA AGATACCGGC AGCTCTGCGT CTTCTGGACA 
GTCAATTACA ACTTTGAGGA GGATCACATG AGGAAGTTCC TACTGACCCA GATCCAGAAA 
AAGAGGCCTG TGATCCTGGA TCCAGCAGAT CCCACAGGTG ATGTGGGAGG AGGTGACCGC 
TGGTGTTGGC ATCTTCTAGC CAAAGAAGCA AAGGAGTGGC TGTCCTCCTC CTGTTTCCAA 
GTGGAGCCAA AAAGCCCCGT GCAGCCGTGG AAAGTACCAG TAGTACAGAC TCCAGGAAGC 
TGTGGAGCTC AGATCTACCC TGTGGTGGGT GGGGTGTACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001009715.1
CDS	41..2242
Translation	MGNWMPGWSSSGSLGVPPMPVQKLEKSVQVNLEPDEKCLSQTEVSSVPSQKLEEYIQANLKPDEESLKQIDQAVDAISDLLCSEVMIDVLKVVKGGSYGRKTVLRDCSDGTLVLFTGLFKQFQDQKKYQDKLLDLIEQRLKSHEKYKKSVKRKLSLLEVQVSIPGQSILLQLLPTFNPLCISENPSAQVYQNLKRSMDQVKASPGEFSDCFTTLQQRFFEKYPGRLKDLILLVKHWYKQLQDKWIIPSPPPLLYALELLTVYAWEQGCQTKDFDITQGIRTVLQLISQPTNLCVYWLDNYNFEDETVRNNLLHQLNSPRPVILDPTDPTNNVGKDDRFWQLLAEEAQEWLNSLRLNKPHKPCWDVLPMPFFITPSHCLDKFIKDFLQPDKVFLNQIKRAVDIICSFLKETCFQNSDIKVLKIIKGGSTAKGTALQQRSDADIIVFLSSLDSYDSLETERSQYVQEIRKQLEACQKAFNLGVKFDISKWMAPRVLSFTLESKSLKQSVEFDVLPAYDALGQLRSDYTSRLKAYKKLIELYASQDSLKGGEFSVCFTELQRDFIETRPTKLKGLIRLIKHWYKQCERKMKPKASLPPKYALELLTVYAWEHGSGTDGFDTAEGFRTVLDLVIRYRQLCVFWTVNYNFEEDHMRKFLLTQIQKKRPVILDPADPTGDVGGGDRWCWHLLAKEAKEWLSSSCFQVEPKSPVQPWKVPVVQTPGSCGAQIYPVVGGVY

Target ORF information:

RefSeq Version	NM_001009715.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus 2'-5' oligoadenylate synthetase 2 (Oas2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001009715.1

ORF Insert Sequence:

ATGGGAAACT GGATGCCTGG CTGGTCATCC AGTGGGTCTT TGGGGGTGCC CCCCATGCCA 
GTGCAGAAGC TAGAAAAGTC TGTCCAGGTA AACCTTGAAC CAGATGAAAA ATGTCTGAGT 
CAGACCGAGG TGTCCTCTGT ACCATCCCAG AAGCTAGAAG AATATATCCA GGCAAACCTC 
AAACCCGATG AAGAATCTCT GAAGCAGATA GACCAGGCTG TGGATGCCAT CTCTGACCTG 
CTGTGCAGTG AGGTGATGAT CGATGTGCTG AAAGTGGTTA AGGGTGGCTC CTATGGTCGG 
AAAACAGTCC TAAGAGACTG CTCCGATGGT ACACTTGTTC TCTTCACCGG TCTCTTCAAA 
CAGTTCCAAG ACCAGAAGAA ATACCAAGAT AAGCTCCTTG ACTTGATTGA ACAACGGCTG 
AAAAGCCATG AGAAATACAA GAAGTCAGTA AAACGTAAAC TTAGCCTCCT TGAAGTACAA 
GTGTCTATAC CAGGGCAGAG TATACTCTTG CAGTTGCTTC CAACCTTCAA TCCTCTGTGC 
ATCAGTGAGA ATCCCAGCGC CCAGGTCTAT CAGAATCTCA AAAGATCCAT GGATCAAGTA 
AAAGCATCAC CTGGGGAATT CTCAGACTGC TTCACCACAC TGCAGCAGAG GTTTTTCGAG 
AAATATCCCG GGAGACTGAA GGATTTGATT CTATTGGTCA AGCACTGGTA TAAACAGTTG 
CAGGATAAGT GGATAATACC CTCACCTCCG CCATTGCTAT ATGCACTGGA GCTGCTTACT 
GTGTATGCCT GGGAACAGGG CTGCCAGACT AAAGACTTTG ACATCACGCA AGGTATCAGG 
ACTGTGCTGC AACTCATCAG TCAGCCGACA AACCTGTGTG TCTACTGGTT AGACAATTAC 
AACTTTGAGG ATGAGACAGT CCGGAACAAC CTTCTGCACC AGCTCAACTC CCCAAGACCG 
GTCATCTTGG ATCCAACCGA CCCAACCAAC AATGTGGGCA AAGATGACAG GTTCTGGCAG 
CTACTGGCAG AAGAGGCTCA GGAGTGGCTG AACTCTCTCA GACTGAATAA GCCACACAAA 
CCATGTTGGG ATGTTCTGCC CATGCCATTT TTCATCACCC CAAGCCACTG CCTGGACAAG 
TTCATCAAAG ACTTCCTCCA ACCTGACAAG GTCTTCCTAA ACCAAATCAA AAGAGCTGTT 
GACATTATCT GTTCATTCTT AAAAGAGACC TGCTTCCAGA ATTCTGACAT CAAAGTCCTG 
AAGATCATCA AGGGAGGATC CACTGCCAAA GGCACAGCTC TGCAGCAGAG ATCAGATGCT 
GACATCATAG TGTTCCTCAG CTCACTGGAT AGTTATGACT CCCTAGAAAC TGAACGCTCC 
CAGTACGTCC AGGAGATCCG AAAGCAGTTA GAAGCCTGCC AGAAGGCCTT TAATTTAGGG 
GTGAAGTTTG ATATTTCCAA ATGGATGGCC CCCAGGGTGC TGAGTTTTAC CCTGGAATCC 
AAGAGTCTCA AGCAAAGTGT GGAGTTCGAT GTCCTTCCCG CCTATGATGC ACTAGGTCAG 
CTGCGGTCTG ACTACACCTC CAGGCTCAAA GCCTACAAGA AGCTCATTGA GCTGTATGCC 
TCACAGGACA GCCTCAAAGG AGGGGAGTTT TCAGTCTGTT TTACAGAGCT ACAGAGAGAC 
TTCATTGAAA CCAGGCCCAC CAAACTCAAG GGTCTGATCC GCCTGATCAA GCACTGGTAC 
AAACAGTGTG AAAGGAAGAT GAAGCCAAAA GCATCTTTGC CTCCAAAGTA CGCACTGGAG 
CTGCTCACCG TGTATGCGTG GGAGCATGGC AGTGGCACAG ATGGCTTCGA CACTGCTGAA 
GGCTTCCGGA CCGTCCTGGA CTTGGTCATA AGATACCGGC AGCTCTGCGT CTTCTGGACA 
GTCAATTACA ACTTTGAGGA GGATCACATG AGGAAGTTCC TACTGACCCA GATCCAGAAA 
AAGAGGCCTG TGATCCTGGA TCCAGCAGAT CCCACAGGTG ATGTGGGAGG AGGTGACCGC 
TGGTGTTGGC ATCTTCTAGC CAAAGAAGCA AAGGAGTGGC TGTCCTCCTC CTGTTTCCAA 
GTGGAGCCAA AAAGCCCCGT GCAGCCGTGG AAAGTACCAG TAGTACAGAC TCCAGGAAGC 
TGTGGAGCTC AGATCTACCC TGTGGTGGGT GGGGTGTACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A mutation in the viral sensor 2'-5'-oligoadenylate synthetase 2 causes failure of lactation.
PLoS genetics13(11)e1007072(2017 Nov)
Oakes SR,Gallego-Ortega D,Stanford PM,Junankar S,Au WWY,Kikhtyak Z,von Korff A,Sergio CM,Law AMK,Castillo LE,Allerdice SL,Young AIJ,Piggin C,Whittle B,Bertram E,Naylor MJ,Roden DL,Donovan J,Korennykh A,Goodnow CC,O'Bryan MK,Ormandy CJ

Impact of lactobacilli on orally acquired listeriosis.
Proceedings of the National Academy of Sciences of the United States of America109(41)16684-9(2012 Oct)
Archambaud C,Nahori MA,Soubigou G,B?cavin C,Laval L,Lechat P,Smokvina T,Langella P,Lecuit M,Cossart P

Defining the membrane proteome of NK cells.
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Ghosh D,Lippert D,Krokhin O,Cortens JP,Wilkins JA

Distinct antiviral roles for human 2',5'-oligoadenylate synthetase family members against dengue virus infection.
Journal of immunology (Baltimore, Md. : 1950)183(12)8035-43(2009 Dec)
Lin RJ,Yu HP,Chang BL,Tang WC,Liao CL,Lin YL

The mammalian 2'-5' oligoadenylate synthetase gene family: evidence for concerted evolution of paralogous Oas1 genes in Rodentia and Artiodactyla.
Journal of molecular evolution63(4)562-76(2006 Oct)
Perelygin AA,Zharkikh AA,Scherbik SV,Brinton MA

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Oas2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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