OAS2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	OAS2
Entrez Gene ID	4939
Full Name	2'-5'-oligoadenylate synthetase 2
General protein information	Preferred Names 2'-5'-oligoadenylate synthetase 2 Names 2'-5'-oligoadenylate synthase 2 (2'-5')oligo(A) synthetase 2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 2-5A synthase 2 p69 OAS / p71 OAS
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q24.13
Summary	This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
Disorder MIM:	603350

mRNA and Protein(s)

mRNA	Protein	Name
NM_001032731.2	NP_001027903.1	2'-5'-oligoadenylate synthase 2 isoform 3
NM_016817.3	NP_058197.2	2'-5'-oligoadenylate synthase 2 isoform 1
NM_016817.2	NP_058197.2	2'-5'-oligoadenylate synthase 2 isoform 1
NM_001032731.1	NP_001027903.1	2'-5'-oligoadenylate synthase 2 isoform 3
NM_002535.2	NP_002526.2	2'-5'-oligoadenylate synthase 2 isoform 2
NM_002535.3	NP_002526.2	2'-5'-oligoadenylate synthase 2 isoform 2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	OAS2	NP_001041599.1
Homo sapiens (human)	OAS2	NP_058197.2
Pan troglodytes (chimpanzee)	OAS2	XP_001151534.1
	OAS2	XP_001110954.1
Bos taurus (cattle)	OAS2	NP_001019728.1
Mus musculus (house mouse)	Oas2	NP_660262.2
Rattus norvegicus (Norway rat)	Oas2	NP_001009715.1

Gene Ontology
Bibliography

Related articles in PubMed

Mx1, OAS1 and OAS2 polymorphisms are associated with the severity of liver disease in HIV/HCV-coinfected patients: A cross-sectional study.
Garc?a-?lvarez M, Berenguer J, Jim?nez-Sousa MA, Pineda-Tenor D, Ald?miz-Echevarria T, Tejerina F, Diez C, V?zquez-Mor?n S, Resino S
Scientific reports741516(2017 Jan)

Adaptively introgressed Neandertal haplotype at the OAS locus functionally impacts innate immune responses in humans.
Sams AJ, Dumaine A, N?d?lec Y, Yotova V, Alfieri C, Tanner JE, Messer PW, Barreiro LB
Genome biology17(1)246(2016 Nov)

Epigenetic regulation of OAS2 shows disease-specific DNA methylation profiles at individual CpG sites.
Gu X, Boldrup L, Coates PJ, Fahraeus R, Nylander E, Loizou C, Olofsson K, Norberg-Spaak L, G?rskog O, Nylander K
Scientific reports632579(2016 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

we characterized the functional consequences of the Neandertal haplotype in the transcriptional regulation of OAS genes at baseline and infected conditions. We found that cells from people with the Neandertal-like haplotype express lower levels of OAS3 upon infection, as well as distinct isoforms of OAS1 and OAS2
Title: Adaptively introgressed Neandertal haplotype at the OAS locus functionally impacts innate immune responses in humans.

Suggest 2'5'-oligoadenylate synthetase 2 mediates T-cell receptor CD3-zeta chain down-regulation via caspase-3 activation in oral cancer.
Title: Extracellular 2'5'-oligoadenylate synthetase 2 mediates T-cell receptor CD3-? chain down-regulation via caspase-3 activation in oral cancer.

Data obtained suggest that the OAS2 rs1293762 and CD209 rs2287886 SNPs are associated with predisposition to chronic hepatitis C in Russian population.
Title: Association between polymorphisms in OAS2 and CD209 genes and predisposition to chronic hepatitis C in Russian population.

Primary mononuclear cells from patients with systemic sclerosis have increased basal levels of OASL and OAS2 genes.
Title: Differential upregulation of human 2'5'OAS genes on systemic sclerosis: Detection of increased basal levels of OASL and OAS2 genes through a qPCR based assay.

The results suggest that OAS1-OAS3-OAS2 haplotypes are associated with differential susceptibility to clinical outcomes of dengue infection.
Title: Polymorphisms in the oligoadenylate synthetase gene cluster and its association with clinical outcomes of dengue virus infection.

The following OAS2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the OAS2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu00823	NM_001032731.2 Latest version!	Homo sapiens 2'-5'-oligoadenylate synthetase 2 (OAS2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu19262	NM_016817.3 Latest version!	Homo sapiens 2'-5'-oligoadenylate synthetase 2 (OAS2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$364.50-$510.30 $729.00
OHu03082	NM_002535.3 Latest version!	Homo sapiens 2'-5'-oligoadenylate synthetase 2 (OAS2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
View Old Accession Versions >>
OHu19262	NM_016817.2	Homo sapiens 2'-5'-oligoadenylate synthetase 2 (OAS2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$364.50-$510.30 $729.00
OHu00823	NM_001032731.1	Homo sapiens 2'-5'-oligoadenylate synthetase 2 (OAS2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu03082	NM_002535.2	Homo sapiens 2'-5'-oligoadenylate synthetase 2 (OAS2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

OAS2 ( NM_001032731.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001027903.1 Homo sapiens 2'-5'-oligoadenylate synthetase 2 (OAS2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu00823
Clone ID Related Accession (Same CDS sequence)	NM_001032731.2 , NM_001032731.1
Accession Version	NM_001032731.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 519bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Homo sapiens(human)
Product	2'-5'-oligoadenylate synthase 2 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BE885222.1, AC004551.1 and BC069052.1. On Jun 2, 2019 this sequence version replaced NM_001032731.1. Transcript Variant: This variant (3) contains an additional segment in the 5' coding region, compared to variant 1, which leads to a premature stop codon. It encodes isoform 3, which has a shorter, distinct N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC023637.2, SRR1163657.376310.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAAATG GGGAGTCCCA GCTGTCCTCG GTGCCTGCTC AGAAGCTGGG TTGGTTTATC 
CAGGAATACC TGAAGCCCTA CGAAGAATGT CAGACACTGA TCGACGAGAT GGTGAACACC 
ATCTGTGACG TCCTGCAGGA ACCCGAACAG TTCCCCCTGG TGCAGGGAGT GGCCATAGGT 
GGCTCCTATG GACGGAAAAC AGTCTTAAGA GGCAACTCCG ATGGTACCCT TGTCCTCTTC 
TTCAGTGACT TAAAACAATT CCAGGATCAG AAGAGAAGCC AACGTGACAT CCTCGATAAA 
ACTGGGGATA AGCTGAAGTT CTGTCTGTTC ACGAAGTGGT TGAAAAACAA TTTCGAGATC 
CAGAAGTCCC TTGATGGGTT CACCATCCAG GTGTTCACAA AAAATCAGAG AATCTCTTTC 
GAGGTGCTGG CCGCCTTCAA CGCTCTGAGT AAGCATTGCT GGGTGTCAGG AGAGAAAAGC 
CAAAGAAGCG GGTGCCAGAC AGCTCTGTGC AACCTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001027903.1
CDS	91..609
Translation	MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIGGSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEIQKSLDGFTIQVFTKNQRISFEVLAAFNALSKHCWVSGEKSQRSGCQTALCNL

Target ORF information:

RefSeq Version	NM_001032731.2
Organism	Homo sapiens(human)
Definition	Homo sapiens 2'-5'-oligoadenylate synthetase 2 (OAS2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001032731.2

ORF Insert Sequence:

ATGGGAAATG GGGAGTCCCA GCTGTCCTCG GTGCCTGCTC AGAAGCTGGG TTGGTTTATC 
CAGGAATACC TGAAGCCCTA CGAAGAATGT CAGACACTGA TCGACGAGAT GGTGAACACC 
ATCTGTGACG TCCTGCAGGA ACCCGAACAG TTCCCCCTGG TGCAGGGAGT GGCCATAGGT 
GGCTCCTATG GACGGAAAAC AGTCTTAAGA GGCAACTCCG ATGGTACCCT TGTCCTCTTC 
TTCAGTGACT TAAAACAATT CCAGGATCAG AAGAGAAGCC AACGTGACAT CCTCGATAAA 
ACTGGGGATA AGCTGAAGTT CTGTCTGTTC ACGAAGTGGT TGAAAAACAA TTTCGAGATC 
CAGAAGTCCC TTGATGGGTT CACCATCCAG GTGTTCACAA AAAATCAGAG AATCTCTTTC 
GAGGTGCTGG CCGCCTTCAA CGCTCTGAGT AAGCATTGCT GGGTGTCAGG AGAGAAAAGC 
CAAAGAAGCG GGTGCCAGAC AGCTCTGTGC AACCTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

OAS2 ( NM_001032731.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001027903.1 Homo sapiens 2'-5'-oligoadenylate synthetase 2 (OAS2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu00823
Clone ID Related Accession (Same CDS sequence)	NM_001032731.2 , NM_001032731.1
Accession Version	NM_001032731.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 519bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	2'-5'-oligoadenylate synthase 2 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BE885222.1, AC004551.1 and BC069052.1. Transcript Variant: This variant (3) contains an additional segment in the 5' coding region, compared to variant 1, which leads to a premature stop codon. It encodes isoform 3, which has a shorter, distinct N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.51340.1, BC010625.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAAATG GGGAGTCCCA GCTGTCCTCG GTGCCTGCTC AGAAGCTGGG TTGGTTTATC 
CAGGAATACC TGAAGCCCTA CGAAGAATGT CAGACACTGA TCGACGAGAT GGTGAACACC 
ATCTGTGACG TCCTGCAGGA ACCCGAACAG TTCCCCCTGG TGCAGGGAGT GGCCATAGGT 
GGCTCCTATG GACGGAAAAC AGTCTTAAGA GGCAACTCCG ATGGTACCCT TGTCCTCTTC 
TTCAGTGACT TAAAACAATT CCAGGATCAG AAGAGAAGCC AACGTGACAT CCTCGATAAA 
ACTGGGGATA AGCTGAAGTT CTGTCTGTTC ACGAAGTGGT TGAAAAACAA TTTCGAGATC 
CAGAAGTCCC TTGATGGGTT CACCATCCAG GTGTTCACAA AAAATCAGAG AATCTCTTTC 
GAGGTGCTGG CCGCCTTCAA CGCTCTGAGT AAGCATTGCT GGGTGTCAGG AGAGAAAAGC 
CAAAGAAGCG GGTGCCAGAC AGCTCTGTGC AACCTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001027903.1
CDS	141..659
Translation	MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIGGSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEIQKSLDGFTIQVFTKNQRISFEVLAAFNALSKHCWVSGEKSQRSGCQTALCNL

Target ORF information:

RefSeq Version	NM_001032731.1
Organism	Homo sapiens(human)
Definition	Homo sapiens 2'-5'-oligoadenylate synthetase 2 (OAS2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001032731.1

ORF Insert Sequence:

ATGGGAAATG GGGAGTCCCA GCTGTCCTCG GTGCCTGCTC AGAAGCTGGG TTGGTTTATC 
CAGGAATACC TGAAGCCCTA CGAAGAATGT CAGACACTGA TCGACGAGAT GGTGAACACC 
ATCTGTGACG TCCTGCAGGA ACCCGAACAG TTCCCCCTGG TGCAGGGAGT GGCCATAGGT 
GGCTCCTATG GACGGAAAAC AGTCTTAAGA GGCAACTCCG ATGGTACCCT TGTCCTCTTC 
TTCAGTGACT TAAAACAATT CCAGGATCAG AAGAGAAGCC AACGTGACAT CCTCGATAAA 
ACTGGGGATA AGCTGAAGTT CTGTCTGTTC ACGAAGTGGT TGAAAAACAA TTTCGAGATC 
CAGAAGTCCC TTGATGGGTT CACCATCCAG GTGTTCACAA AAAATCAGAG AATCTCTTTC 
GAGGTGCTGG CCGCCTTCAA CGCTCTGAGT AAGCATTGCT GGGTGTCAGG AGAGAAAAGC 
CAAAGAAGCG GGTGCCAGAC AGCTCTGTGC AACCTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

OAS2 ( NM_016817.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_058197.2 Homo sapiens 2'-5'-oligoadenylate synthetase 2 (OAS2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu19262
Clone ID Related Accession (Same CDS sequence)	NM_016817.3 , NM_016817.2
Accession Version	NM_016817.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2160bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	2'-5'-oligoadenylate synthase 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BE885222.1, BC049215.1, BQ213828.1 and AC004551.1. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2019 this sequence version replaced NM_016817.2. Transcript Variant: This variant (1) encodes the longest isoform (1), which is also known as the p71 isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.140780.1, SRR1660807.25592.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAAATG GGGAGTCCCA GCTGTCCTCG GTGCCTGCTC AGAAGCTGGG TTGGTTTATC 
CAGGAATACC TGAAGCCCTA CGAAGAATGT CAGACACTGA TCGACGAGAT GGTGAACACC 
ATCTGTGACG TCCTGCAGGA ACCCGAACAG TTCCCCCTGG TGCAGGGAGT GGCCATAGGT 
GGCTCCTATG GACGGAAAAC AGTCTTAAGA GGCAACTCCG ATGGTACCCT TGTCCTCTTC 
TTCAGTGACT TAAAACAATT CCAGGATCAG AAGAGAAGCC AACGTGACAT CCTCGATAAA 
ACTGGGGATA AGCTGAAGTT CTGTCTGTTC ACGAAGTGGT TGAAAAACAA TTTCGAGATC 
CAGAAGTCCC TTGATGGGTT CACCATCCAG GTGTTCACAA AAAATCAGAG AATCTCTTTC 
GAGGTGCTGG CCGCCTTCAA CGCTCTGAGC TTAAATGATA ATCCCAGCCC CTGGATCTAT 
CGAGAGCTCA AAAGATCCTT GGATAAGACA AATGCCAGTC CTGGTGAGTT TGCAGTCTGC 
TTCACTGAAC TCCAGCAGAA GTTTTTTGAC AACCGTCCTG GAAAACTAAA GGATTTGATC 
CTCTTGATAA AGCACTGGCA TCAACAGTGC CAGAAAAAAA TCAAGGATTT ACCCTCGCTG 
TCTCCGTATG CCCTGGAGCT GCTTACGGTG TATGCCTGGG AACAGGGGTG CAGAAAAGAC 
AACTTTGACA TTGCTGAAGG CGTCAGAACC GTACTGGAGC TGATCAAATG CCAGGAGAAG 
CTGTGTATCT ATTGGATGGT CAACTACAAC TTTGAAGATG AGACCATCAG GAACATCCTG 
CTGCACCAGC TCCAATCAGC GAGGCCAGTA ATCTTGGATC CAGTTGACCC AACCAATAAT 
GTGAGTGGAG ATAAAATATG CTGGCAATGG CTGAAAAAAG AAGCTCAAAC CTGGTTGACT 
TCTCCCAACC TGGATAATGA GTTACCTGCA CCATCTTGGA ATGTTCTGCC TGCACCACTC 
TTCACGACCC CAGGCCACCT TCTGGATAAG TTCATCAAGG AGTTTCTCCA GCCCAACAAA 
TGCTTCCTAG AGCAGATTGA CAGTGCTGTT AACATCATCC GTACATTCCT TAAAGAAAAC 
TGCTTCCGAC AATCAACAGC CAAGATCCAG ATTGTCCGGG GAGGATCAAC CGCCAAAGGC 
ACAGCTCTGA AGACTGGCTC TGATGCCGAT CTCGTCGTGT TCCATAACTC ACTTAAAAGC 
TACACCTCCC AAAAAAACGA GCGGCACAAA ATCGTCAAGG AAATCCATGA ACAGCTGAAA 
GCCTTTTGGA GGGAGAAGGA GGAGGAGCTT GAAGTCAGCT TTGAGCCTCC CAAGTGGAAG 
GCTCCCAGGG TGCTGAGCTT CTCTCTGAAA TCCAAAGTCC TCAACGAAAG TGTCAGCTTT 
GATGTGCTTC CTGCCTTTAA TGCACTGGGT CAGCTGAGTT CTGGCTCCAC ACCCAGCCCC 
GAGGTTTATG CAGGGCTCAT TGATCTGTAT AAATCCTCGG ACCTCCCGGG AGGAGAGTTT 
TCTACCTGTT TCACAGTCCT GCAGCGAAAC TTCATTCGCT CCCGGCCCAC CAAACTAAAG 
GATTTAATTC GCCTGGTGAA GCACTGGTAC AAAGAGTGTG AAAGGAAACT GAAGCCAAAG 
GGGTCTTTGC CCCCAAAGTA TGCCTTGGAG CTGCTCACCA TCTATGCCTG GGAGCAGGGG 
AGTGGAGTGC CGGATTTTGA CACTGCAGAA GGTTTCCGGA CAGTCCTGGA GCTGGTCACA 
CAATATCAGC AGCTCTGCAT CTTCTGGAAG GTCAATTACA ACTTTGAAGA TGAGACCGTG 
AGGAAGTTTC TACTGAGCCA GTTGCAGAAA ACCAGGCCTG TGATCTTGGA CCCAGCCGAA 
CCCACAGGTG ACGTGGGTGG AGGGGACCGT TGGTGTTGGC ATCTTCTGGC AAAAGAAGCA 
AAGGAATGGT TATCCTCTCC CTGCTTCAAG GATGGGACTG GAAACCCAAT ACCACCTTGG 
AAAGTGCCGA CAATGCAGAC ACCAGGAAGT TGTGGAGCTA GGATCCATCC TATTGTCAAT 
GAGATGTTCT CATCCAGAAG CCATAGAATC CTGAATAATA ATTCTAAAAG AAACTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058197.2
CDS	91..2250
Translation	MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIGGSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEIQKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVCFTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILDPVDPTNNVSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPWKVPTMQTPGSCGARIHPIVNEMFSSRSHRILNNNSKRNF

Target ORF information:

RefSeq Version	NM_016817.3
Organism	Homo sapiens(human)
Definition	Homo sapiens 2'-5'-oligoadenylate synthetase 2 (OAS2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016817.3

ORF Insert Sequence:

ATGGGAAATG GGGAGTCCCA GCTGTCCTCG GTGCCTGCTC AGAAGCTGGG TTGGTTTATC 
CAGGAATACC TGAAGCCCTA CGAAGAATGT CAGACACTGA TCGACGAGAT GGTGAACACC 
ATCTGTGACG TCCTGCAGGA ACCCGAACAG TTCCCCCTGG TGCAGGGAGT GGCCATAGGT 
GGCTCCTATG GACGGAAAAC AGTCTTAAGA GGCAACTCCG ATGGTACCCT TGTCCTCTTC 
TTCAGTGACT TAAAACAATT CCAGGATCAG AAGAGAAGCC AACGTGACAT CCTCGATAAA 
ACTGGGGATA AGCTGAAGTT CTGTCTGTTC ACGAAGTGGT TGAAAAACAA TTTCGAGATC 
CAGAAGTCCC TTGATGGGTT CACCATCCAG GTGTTCACAA AAAATCAGAG AATCTCTTTC 
GAGGTGCTGG CCGCCTTCAA CGCTCTGAGC TTAAATGATA ATCCCAGCCC CTGGATCTAT 
CGAGAGCTCA AAAGATCCTT GGATAAGACA AATGCCAGTC CTGGTGAGTT TGCAGTCTGC 
TTCACTGAAC TCCAGCAGAA GTTTTTTGAC AACCGTCCTG GAAAACTAAA GGATTTGATC 
CTCTTGATAA AGCACTGGCA TCAACAGTGC CAGAAAAAAA TCAAGGATTT ACCCTCGCTG 
TCTCCGTATG CCCTGGAGCT GCTTACGGTG TATGCCTGGG AACAGGGGTG CAGAAAAGAC 
AACTTTGACA TTGCTGAAGG CGTCAGAACC GTACTGGAGC TGATCAAATG CCAGGAGAAG 
CTGTGTATCT ATTGGATGGT CAACTACAAC TTTGAAGATG AGACCATCAG GAACATCCTG 
CTGCACCAGC TCCAATCAGC GAGGCCAGTA ATCTTGGATC CAGTTGACCC AACCAATAAT 
GTGAGTGGAG ATAAAATATG CTGGCAATGG CTGAAAAAAG AAGCTCAAAC CTGGTTGACT 
TCTCCCAACC TGGATAATGA GTTACCTGCA CCATCTTGGA ATGTTCTGCC TGCACCACTC 
TTCACGACCC CAGGCCACCT TCTGGATAAG TTCATCAAGG AGTTTCTCCA GCCCAACAAA 
TGCTTCCTAG AGCAGATTGA CAGTGCTGTT AACATCATCC GTACATTCCT TAAAGAAAAC 
TGCTTCCGAC AATCAACAGC CAAGATCCAG ATTGTCCGGG GAGGATCAAC CGCCAAAGGC 
ACAGCTCTGA AGACTGGCTC TGATGCCGAT CTCGTCGTGT TCCATAACTC ACTTAAAAGC 
TACACCTCCC AAAAAAACGA GCGGCACAAA ATCGTCAAGG AAATCCATGA ACAGCTGAAA 
GCCTTTTGGA GGGAGAAGGA GGAGGAGCTT GAAGTCAGCT TTGAGCCTCC CAAGTGGAAG 
GCTCCCAGGG TGCTGAGCTT CTCTCTGAAA TCCAAAGTCC TCAACGAAAG TGTCAGCTTT 
GATGTGCTTC CTGCCTTTAA TGCACTGGGT CAGCTGAGTT CTGGCTCCAC ACCCAGCCCC 
GAGGTTTATG CAGGGCTCAT TGATCTGTAT AAATCCTCGG ACCTCCCGGG AGGAGAGTTT 
TCTACCTGTT TCACAGTCCT GCAGCGAAAC TTCATTCGCT CCCGGCCCAC CAAACTAAAG 
GATTTAATTC GCCTGGTGAA GCACTGGTAC AAAGAGTGTG AAAGGAAACT GAAGCCAAAG 
GGGTCTTTGC CCCCAAAGTA TGCCTTGGAG CTGCTCACCA TCTATGCCTG GGAGCAGGGG 
AGTGGAGTGC CGGATTTTGA CACTGCAGAA GGTTTCCGGA CAGTCCTGGA GCTGGTCACA 
CAATATCAGC AGCTCTGCAT CTTCTGGAAG GTCAATTACA ACTTTGAAGA TGAGACCGTG 
AGGAAGTTTC TACTGAGCCA GTTGCAGAAA ACCAGGCCTG TGATCTTGGA CCCAGCCGAA 
CCCACAGGTG ACGTGGGTGG AGGGGACCGT TGGTGTTGGC ATCTTCTGGC AAAAGAAGCA 
AAGGAATGGT TATCCTCTCC CTGCTTCAAG GATGGGACTG GAAACCCAAT ACCACCTTGG 
AAAGTGCCGA CAATGCAGAC ACCAGGAAGT TGTGGAGCTA GGATCCATCC TATTGTCAAT 
GAGATGTTCT CATCCAGAAG CCATAGAATC CTGAATAATA ATTCTAAAAG AAACTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

OAS2 ( NM_016817.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_058197.2 Homo sapiens 2'-5'-oligoadenylate synthetase 2 (OAS2), transcript variant 1, mRNA.

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CloneID	OHu19262
Clone ID Related Accession (Same CDS sequence)	NM_016817.3 , NM_016817.2
Accession Version	NM_016817.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2160bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	2'-5'-oligoadenylate synthase 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BE885222.1, BC049215.1, BQ213828.1 and AC004551.1. This sequence is a reference standard in the RefSeqGene project. On Sep 7, 2005 this sequence version replaced NM_016817.1. Transcript Variant: This variant (1) encodes the longest isoform (1), which is also known as the p71 isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.140780.1, M87434.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAAATG GGGAGTCCCA GCTGTCCTCG GTGCCTGCTC AGAAGCTGGG TTGGTTTATC 
CAGGAATACC TGAAGCCCTA CGAAGAATGT CAGACACTGA TCGACGAGAT GGTGAACACC 
ATCTGTGACG TCCTGCAGGA ACCCGAACAG TTCCCCCTGG TGCAGGGAGT GGCCATAGGT 
GGCTCCTATG GACGGAAAAC AGTCTTAAGA GGCAACTCCG ATGGTACCCT TGTCCTCTTC 
TTCAGTGACT TAAAACAATT CCAGGATCAG AAGAGAAGCC AACGTGACAT CCTCGATAAA 
ACTGGGGATA AGCTGAAGTT CTGTCTGTTC ACGAAGTGGT TGAAAAACAA TTTCGAGATC 
CAGAAGTCCC TTGATGGGTT CACCATCCAG GTGTTCACAA AAAATCAGAG AATCTCTTTC 
GAGGTGCTGG CCGCCTTCAA CGCTCTGAGC TTAAATGATA ATCCCAGCCC CTGGATCTAT 
CGAGAGCTCA AAAGATCCTT GGATAAGACA AATGCCAGTC CTGGTGAGTT TGCAGTCTGC 
TTCACTGAAC TCCAGCAGAA GTTTTTTGAC AACCGTCCTG GAAAACTAAA GGATTTGATC 
CTCTTGATAA AGCACTGGCA TCAACAGTGC CAGAAAAAAA TCAAGGATTT ACCCTCGCTG 
TCTCCGTATG CCCTGGAGCT GCTTACGGTG TATGCCTGGG AACAGGGGTG CAGAAAAGAC 
AACTTTGACA TTGCTGAAGG CGTCAGAACC GTACTGGAGC TGATCAAATG CCAGGAGAAG 
CTGTGTATCT ATTGGATGGT CAACTACAAC TTTGAAGATG AGACCATCAG GAACATCCTG 
CTGCACCAGC TCCAATCAGC GAGGCCAGTA ATCTTGGATC CAGTTGACCC AACCAATAAT 
GTGAGTGGAG ATAAAATATG CTGGCAATGG CTGAAAAAAG AAGCTCAAAC CTGGTTGACT 
TCTCCCAACC TGGATAATGA GTTACCTGCA CCATCTTGGA ATGTTCTGCC TGCACCACTC 
TTCACGACCC CAGGCCACCT TCTGGATAAG TTCATCAAGG AGTTTCTCCA GCCCAACAAA 
TGCTTCCTAG AGCAGATTGA CAGTGCTGTT AACATCATCC GTACATTCCT TAAAGAAAAC 
TGCTTCCGAC AATCAACAGC CAAGATCCAG ATTGTCCGGG GAGGATCAAC CGCCAAAGGC 
ACAGCTCTGA AGACTGGCTC TGATGCCGAT CTCGTCGTGT TCCATAACTC ACTTAAAAGC 
TACACCTCCC AAAAAAACGA GCGGCACAAA ATCGTCAAGG AAATCCATGA ACAGCTGAAA 
GCCTTTTGGA GGGAGAAGGA GGAGGAGCTT GAAGTCAGCT TTGAGCCTCC CAAGTGGAAG 
GCTCCCAGGG TGCTGAGCTT CTCTCTGAAA TCCAAAGTCC TCAACGAAAG TGTCAGCTTT 
GATGTGCTTC CTGCCTTTAA TGCACTGGGT CAGCTGAGTT CTGGCTCCAC ACCCAGCCCC 
GAGGTTTATG CAGGGCTCAT TGATCTGTAT AAATCCTCGG ACCTCCCGGG AGGAGAGTTT 
TCTACCTGTT TCACAGTCCT GCAGCGAAAC TTCATTCGCT CCCGGCCCAC CAAACTAAAG 
GATTTAATTC GCCTGGTGAA GCACTGGTAC AAAGAGTGTG AAAGGAAACT GAAGCCAAAG 
GGGTCTTTGC CCCCAAAGTA TGCCTTGGAG CTGCTCACCA TCTATGCCTG GGAGCAGGGG 
AGTGGAGTGC CGGATTTTGA CACTGCAGAA GGTTTCCGGA CAGTCCTGGA GCTGGTCACA 
CAATATCAGC AGCTCTGCAT CTTCTGGAAG GTCAATTACA ACTTTGAAGA TGAGACCGTG 
AGGAAGTTTC TACTGAGCCA GTTGCAGAAA ACCAGGCCTG TGATCTTGGA CCCAGCCGAA 
CCCACAGGTG ACGTGGGTGG AGGGGACCGT TGGTGTTGGC ATCTTCTGGC AAAAGAAGCA 
AAGGAATGGT TATCCTCTCC CTGCTTCAAG GATGGGACTG GAAACCCAAT ACCACCTTGG 
AAAGTGCCGA CAATGCAGAC ACCAGGAAGT TGTGGAGCTA GGATCCATCC TATTGTCAAT 
GAGATGTTCT CATCCAGAAG CCATAGAATC CTGAATAATA ATTCTAAAAG AAACTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058197.2
CDS	141..2300
Translation	MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIGGSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEIQKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVCFTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILDPVDPTNNVSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPWKVPTMQTPGSCGARIHPIVNEMFSSRSHRILNNNSKRNF

Target ORF information:

RefSeq Version	NM_016817.2
Organism	Homo sapiens(human)
Definition	Homo sapiens 2'-5'-oligoadenylate synthetase 2 (OAS2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016817.2

ORF Insert Sequence:

ATGGGAAATG GGGAGTCCCA GCTGTCCTCG GTGCCTGCTC AGAAGCTGGG TTGGTTTATC 
CAGGAATACC TGAAGCCCTA CGAAGAATGT CAGACACTGA TCGACGAGAT GGTGAACACC 
ATCTGTGACG TCCTGCAGGA ACCCGAACAG TTCCCCCTGG TGCAGGGAGT GGCCATAGGT 
GGCTCCTATG GACGGAAAAC AGTCTTAAGA GGCAACTCCG ATGGTACCCT TGTCCTCTTC 
TTCAGTGACT TAAAACAATT CCAGGATCAG AAGAGAAGCC AACGTGACAT CCTCGATAAA 
ACTGGGGATA AGCTGAAGTT CTGTCTGTTC ACGAAGTGGT TGAAAAACAA TTTCGAGATC 
CAGAAGTCCC TTGATGGGTT CACCATCCAG GTGTTCACAA AAAATCAGAG AATCTCTTTC 
GAGGTGCTGG CCGCCTTCAA CGCTCTGAGC TTAAATGATA ATCCCAGCCC CTGGATCTAT 
CGAGAGCTCA AAAGATCCTT GGATAAGACA AATGCCAGTC CTGGTGAGTT TGCAGTCTGC 
TTCACTGAAC TCCAGCAGAA GTTTTTTGAC AACCGTCCTG GAAAACTAAA GGATTTGATC 
CTCTTGATAA AGCACTGGCA TCAACAGTGC CAGAAAAAAA TCAAGGATTT ACCCTCGCTG 
TCTCCGTATG CCCTGGAGCT GCTTACGGTG TATGCCTGGG AACAGGGGTG CAGAAAAGAC 
AACTTTGACA TTGCTGAAGG CGTCAGAACC GTACTGGAGC TGATCAAATG CCAGGAGAAG 
CTGTGTATCT ATTGGATGGT CAACTACAAC TTTGAAGATG AGACCATCAG GAACATCCTG 
CTGCACCAGC TCCAATCAGC GAGGCCAGTA ATCTTGGATC CAGTTGACCC AACCAATAAT 
GTGAGTGGAG ATAAAATATG CTGGCAATGG CTGAAAAAAG AAGCTCAAAC CTGGTTGACT 
TCTCCCAACC TGGATAATGA GTTACCTGCA CCATCTTGGA ATGTTCTGCC TGCACCACTC 
TTCACGACCC CAGGCCACCT TCTGGATAAG TTCATCAAGG AGTTTCTCCA GCCCAACAAA 
TGCTTCCTAG AGCAGATTGA CAGTGCTGTT AACATCATCC GTACATTCCT TAAAGAAAAC 
TGCTTCCGAC AATCAACAGC CAAGATCCAG ATTGTCCGGG GAGGATCAAC CGCCAAAGGC 
ACAGCTCTGA AGACTGGCTC TGATGCCGAT CTCGTCGTGT TCCATAACTC ACTTAAAAGC 
TACACCTCCC AAAAAAACGA GCGGCACAAA ATCGTCAAGG AAATCCATGA ACAGCTGAAA 
GCCTTTTGGA GGGAGAAGGA GGAGGAGCTT GAAGTCAGCT TTGAGCCTCC CAAGTGGAAG 
GCTCCCAGGG TGCTGAGCTT CTCTCTGAAA TCCAAAGTCC TCAACGAAAG TGTCAGCTTT 
GATGTGCTTC CTGCCTTTAA TGCACTGGGT CAGCTGAGTT CTGGCTCCAC ACCCAGCCCC 
GAGGTTTATG CAGGGCTCAT TGATCTGTAT AAATCCTCGG ACCTCCCGGG AGGAGAGTTT 
TCTACCTGTT TCACAGTCCT GCAGCGAAAC TTCATTCGCT CCCGGCCCAC CAAACTAAAG 
GATTTAATTC GCCTGGTGAA GCACTGGTAC AAAGAGTGTG AAAGGAAACT GAAGCCAAAG 
GGGTCTTTGC CCCCAAAGTA TGCCTTGGAG CTGCTCACCA TCTATGCCTG GGAGCAGGGG 
AGTGGAGTGC CGGATTTTGA CACTGCAGAA GGTTTCCGGA CAGTCCTGGA GCTGGTCACA 
CAATATCAGC AGCTCTGCAT CTTCTGGAAG GTCAATTACA ACTTTGAAGA TGAGACCGTG 
AGGAAGTTTC TACTGAGCCA GTTGCAGAAA ACCAGGCCTG TGATCTTGGA CCCAGCCGAA 
CCCACAGGTG ACGTGGGTGG AGGGGACCGT TGGTGTTGGC ATCTTCTGGC AAAAGAAGCA 
AAGGAATGGT TATCCTCTCC CTGCTTCAAG GATGGGACTG GAAACCCAAT ACCACCTTGG 
AAAGTGCCGA CAATGCAGAC ACCAGGAAGT TGTGGAGCTA GGATCCATCC TATTGTCAAT 
GAGATGTTCT CATCCAGAAG CCATAGAATC CTGAATAATA ATTCTAAAAG AAACTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

OAS2 ( NM_002535.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_002526.2 Homo sapiens 2'-5'-oligoadenylate synthetase 2 (OAS2), transcript variant 2, mRNA.

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CloneID	OHu03082
Clone ID Related Accession (Same CDS sequence)	NM_002535.2 , NM_002535.3
Accession Version	NM_002535.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2064bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	2'-5'-oligoadenylate synthase 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BE885222.1, BC049215.1, BQ213828.1 and AC004551.1. On Sep 7, 2005 this sequence version replaced NM_002535.1. Transcript Variant: This variant (2) contains an additional segment in the 3' coding region, compared to variant 1, which leads to a premature stop codon. It encodes isoform 2, also known as p69, which has a shorter, distinct C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.163673.1, SRR1660807.124886.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAAATG GGGAGTCCCA GCTGTCCTCG GTGCCTGCTC AGAAGCTGGG TTGGTTTATC 
CAGGAATACC TGAAGCCCTA CGAAGAATGT CAGACACTGA TCGACGAGAT GGTGAACACC 
ATCTGTGACG TCCTGCAGGA ACCCGAACAG TTCCCCCTGG TGCAGGGAGT GGCCATAGGT 
GGCTCCTATG GACGGAAAAC AGTCTTAAGA GGCAACTCCG ATGGTACCCT TGTCCTCTTC 
TTCAGTGACT TAAAACAATT CCAGGATCAG AAGAGAAGCC AACGTGACAT CCTCGATAAA 
ACTGGGGATA AGCTGAAGTT CTGTCTGTTC ACGAAGTGGT TGAAAAACAA TTTCGAGATC 
CAGAAGTCCC TTGATGGGTT CACCATCCAG GTGTTCACAA AAAATCAGAG AATCTCTTTC 
GAGGTGCTGG CCGCCTTCAA CGCTCTGAGC TTAAATGATA ATCCCAGCCC CTGGATCTAT 
CGAGAGCTCA AAAGATCCTT GGATAAGACA AATGCCAGTC CTGGTGAGTT TGCAGTCTGC 
TTCACTGAAC TCCAGCAGAA GTTTTTTGAC AACCGTCCTG GAAAACTAAA GGATTTGATC 
CTCTTGATAA AGCACTGGCA TCAACAGTGC CAGAAAAAAA TCAAGGATTT ACCCTCGCTG 
TCTCCGTATG CCCTGGAGCT GCTTACGGTG TATGCCTGGG AACAGGGGTG CAGAAAAGAC 
AACTTTGACA TTGCTGAAGG CGTCAGAACC GTACTGGAGC TGATCAAATG CCAGGAGAAG 
CTGTGTATCT ATTGGATGGT CAACTACAAC TTTGAAGATG AGACCATCAG GAACATCCTG 
CTGCACCAGC TCCAATCAGC GAGGCCAGTA ATCTTGGATC CAGTTGACCC AACCAATAAT 
GTGAGTGGAG ATAAAATATG CTGGCAATGG CTGAAAAAAG AAGCTCAAAC CTGGTTGACT 
TCTCCCAACC TGGATAATGA GTTACCTGCA CCATCTTGGA ATGTTCTGCC TGCACCACTC 
TTCACGACCC CAGGCCACCT TCTGGATAAG TTCATCAAGG AGTTTCTCCA GCCCAACAAA 
TGCTTCCTAG AGCAGATTGA CAGTGCTGTT AACATCATCC GTACATTCCT TAAAGAAAAC 
TGCTTCCGAC AATCAACAGC CAAGATCCAG ATTGTCCGGG GAGGATCAAC CGCCAAAGGC 
ACAGCTCTGA AGACTGGCTC TGATGCCGAT CTCGTCGTGT TCCATAACTC ACTTAAAAGC 
TACACCTCCC AAAAAAACGA GCGGCACAAA ATCGTCAAGG AAATCCATGA ACAGCTGAAA 
GCCTTTTGGA GGGAGAAGGA GGAGGAGCTT GAAGTCAGCT TTGAGCCTCC CAAGTGGAAG 
GCTCCCAGGG TGCTGAGCTT CTCTCTGAAA TCCAAAGTCC TCAACGAAAG TGTCAGCTTT 
GATGTGCTTC CTGCCTTTAA TGCACTGGGT CAGCTGAGTT CTGGCTCCAC ACCCAGCCCC 
GAGGTTTATG CAGGGCTCAT TGATCTGTAT AAATCCTCGG ACCTCCCGGG AGGAGAGTTT 
TCTACCTGTT TCACAGTCCT GCAGCGAAAC TTCATTCGCT CCCGGCCCAC CAAACTAAAG 
GATTTAATTC GCCTGGTGAA GCACTGGTAC AAAGAGTGTG AAAGGAAACT GAAGCCAAAG 
GGGTCTTTGC CCCCAAAGTA TGCCTTGGAG CTGCTCACCA TCTATGCCTG GGAGCAGGGG 
AGTGGAGTGC CGGATTTTGA CACTGCAGAA GGTTTCCGGA CAGTCCTGGA GCTGGTCACA 
CAATATCAGC AGCTCTGCAT CTTCTGGAAG GTCAATTACA ACTTTGAAGA TGAGACCGTG 
AGGAAGTTTC TACTGAGCCA GTTGCAGAAA ACCAGGCCTG TGATCTTGGA CCCAGCCGAA 
CCCACAGGTG ACGTGGGTGG AGGGGACCGT TGGTGTTGGC ATCTTCTGGC AAAAGAAGCA 
AAGGAATGGT TATCCTCTCC CTGCTTCAAG GATGGGACTG GAAACCCAAT ACCACCTTGG 
AAAGTGCCGG TAAAAGTCAT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002526.2
CDS	141..2204
Translation	MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIGGSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEIQKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVCFTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILDPVDPTNNVSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPWKVPVKVI

Target ORF information:

RefSeq Version	NM_002535.2
Organism	Homo sapiens(human)
Definition	Homo sapiens 2'-5'-oligoadenylate synthetase 2 (OAS2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002535.2

ORF Insert Sequence:

ATGGGAAATG GGGAGTCCCA GCTGTCCTCG GTGCCTGCTC AGAAGCTGGG TTGGTTTATC 
CAGGAATACC TGAAGCCCTA CGAAGAATGT CAGACACTGA TCGACGAGAT GGTGAACACC 
ATCTGTGACG TCCTGCAGGA ACCCGAACAG TTCCCCCTGG TGCAGGGAGT GGCCATAGGT 
GGCTCCTATG GACGGAAAAC AGTCTTAAGA GGCAACTCCG ATGGTACCCT TGTCCTCTTC 
TTCAGTGACT TAAAACAATT CCAGGATCAG AAGAGAAGCC AACGTGACAT CCTCGATAAA 
ACTGGGGATA AGCTGAAGTT CTGTCTGTTC ACGAAGTGGT TGAAAAACAA TTTCGAGATC 
CAGAAGTCCC TTGATGGGTT CACCATCCAG GTGTTCACAA AAAATCAGAG AATCTCTTTC 
GAGGTGCTGG CCGCCTTCAA CGCTCTGAGC TTAAATGATA ATCCCAGCCC CTGGATCTAT 
CGAGAGCTCA AAAGATCCTT GGATAAGACA AATGCCAGTC CTGGTGAGTT TGCAGTCTGC 
TTCACTGAAC TCCAGCAGAA GTTTTTTGAC AACCGTCCTG GAAAACTAAA GGATTTGATC 
CTCTTGATAA AGCACTGGCA TCAACAGTGC CAGAAAAAAA TCAAGGATTT ACCCTCGCTG 
TCTCCGTATG CCCTGGAGCT GCTTACGGTG TATGCCTGGG AACAGGGGTG CAGAAAAGAC 
AACTTTGACA TTGCTGAAGG CGTCAGAACC GTACTGGAGC TGATCAAATG CCAGGAGAAG 
CTGTGTATCT ATTGGATGGT CAACTACAAC TTTGAAGATG AGACCATCAG GAACATCCTG 
CTGCACCAGC TCCAATCAGC GAGGCCAGTA ATCTTGGATC CAGTTGACCC AACCAATAAT 
GTGAGTGGAG ATAAAATATG CTGGCAATGG CTGAAAAAAG AAGCTCAAAC CTGGTTGACT 
TCTCCCAACC TGGATAATGA GTTACCTGCA CCATCTTGGA ATGTTCTGCC TGCACCACTC 
TTCACGACCC CAGGCCACCT TCTGGATAAG TTCATCAAGG AGTTTCTCCA GCCCAACAAA 
TGCTTCCTAG AGCAGATTGA CAGTGCTGTT AACATCATCC GTACATTCCT TAAAGAAAAC 
TGCTTCCGAC AATCAACAGC CAAGATCCAG ATTGTCCGGG GAGGATCAAC CGCCAAAGGC 
ACAGCTCTGA AGACTGGCTC TGATGCCGAT CTCGTCGTGT TCCATAACTC ACTTAAAAGC 
TACACCTCCC AAAAAAACGA GCGGCACAAA ATCGTCAAGG AAATCCATGA ACAGCTGAAA 
GCCTTTTGGA GGGAGAAGGA GGAGGAGCTT GAAGTCAGCT TTGAGCCTCC CAAGTGGAAG 
GCTCCCAGGG TGCTGAGCTT CTCTCTGAAA TCCAAAGTCC TCAACGAAAG TGTCAGCTTT 
GATGTGCTTC CTGCCTTTAA TGCACTGGGT CAGCTGAGTT CTGGCTCCAC ACCCAGCCCC 
GAGGTTTATG CAGGGCTCAT TGATCTGTAT AAATCCTCGG ACCTCCCGGG AGGAGAGTTT 
TCTACCTGTT TCACAGTCCT GCAGCGAAAC TTCATTCGCT CCCGGCCCAC CAAACTAAAG 
GATTTAATTC GCCTGGTGAA GCACTGGTAC AAAGAGTGTG AAAGGAAACT GAAGCCAAAG 
GGGTCTTTGC CCCCAAAGTA TGCCTTGGAG CTGCTCACCA TCTATGCCTG GGAGCAGGGG 
AGTGGAGTGC CGGATTTTGA CACTGCAGAA GGTTTCCGGA CAGTCCTGGA GCTGGTCACA 
CAATATCAGC AGCTCTGCAT CTTCTGGAAG GTCAATTACA ACTTTGAAGA TGAGACCGTG 
AGGAAGTTTC TACTGAGCCA GTTGCAGAAA ACCAGGCCTG TGATCTTGGA CCCAGCCGAA 
CCCACAGGTG ACGTGGGTGG AGGGGACCGT TGGTGTTGGC ATCTTCTGGC AAAAGAAGCA 
AAGGAATGGT TATCCTCTCC CTGCTTCAAG GATGGGACTG GAAACCCAAT ACCACCTTGG 
AAAGTGCCGG TAAAAGTCAT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

OAS2 ( NM_002535.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002526.2 Homo sapiens 2'-5'-oligoadenylate synthetase 2 (OAS2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu03082
Clone ID Related Accession (Same CDS sequence)	NM_002535.2 , NM_002535.3
Accession Version	NM_002535.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2064bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-03
Organism	Homo sapiens(human)
Product	2'-5'-oligoadenylate synthase 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BE885222.1, BC049215.1, BQ213828.1 and AC004551.1. On Jun 2, 2019 this sequence version replaced NM_002535.2. Transcript Variant: This variant (2) contains an additional segment in the 3' coding region, compared to variant 1, which leads to a premature stop codon. It encodes isoform 2, also known as p69, which has a shorter, distinct C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7346977.1711286.1, SRR1803615.163673.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGAAATG GGGAGTCCCA GCTGTCCTCG GTGCCTGCTC AGAAGCTGGG TTGGTTTATC 
CAGGAATACC TGAAGCCCTA CGAAGAATGT CAGACACTGA TCGACGAGAT GGTGAACACC 
ATCTGTGACG TCCTGCAGGA ACCCGAACAG TTCCCCCTGG TGCAGGGAGT GGCCATAGGT 
GGCTCCTATG GACGGAAAAC AGTCTTAAGA GGCAACTCCG ATGGTACCCT TGTCCTCTTC 
TTCAGTGACT TAAAACAATT CCAGGATCAG AAGAGAAGCC AACGTGACAT CCTCGATAAA 
ACTGGGGATA AGCTGAAGTT CTGTCTGTTC ACGAAGTGGT TGAAAAACAA TTTCGAGATC 
CAGAAGTCCC TTGATGGGTT CACCATCCAG GTGTTCACAA AAAATCAGAG AATCTCTTTC 
GAGGTGCTGG CCGCCTTCAA CGCTCTGAGC TTAAATGATA ATCCCAGCCC CTGGATCTAT 
CGAGAGCTCA AAAGATCCTT GGATAAGACA AATGCCAGTC CTGGTGAGTT TGCAGTCTGC 
TTCACTGAAC TCCAGCAGAA GTTTTTTGAC AACCGTCCTG GAAAACTAAA GGATTTGATC 
CTCTTGATAA AGCACTGGCA TCAACAGTGC CAGAAAAAAA TCAAGGATTT ACCCTCGCTG 
TCTCCGTATG CCCTGGAGCT GCTTACGGTG TATGCCTGGG AACAGGGGTG CAGAAAAGAC 
AACTTTGACA TTGCTGAAGG CGTCAGAACC GTACTGGAGC TGATCAAATG CCAGGAGAAG 
CTGTGTATCT ATTGGATGGT CAACTACAAC TTTGAAGATG AGACCATCAG GAACATCCTG 
CTGCACCAGC TCCAATCAGC GAGGCCAGTA ATCTTGGATC CAGTTGACCC AACCAATAAT 
GTGAGTGGAG ATAAAATATG CTGGCAATGG CTGAAAAAAG AAGCTCAAAC CTGGTTGACT 
TCTCCCAACC TGGATAATGA GTTACCTGCA CCATCTTGGA ATGTTCTGCC TGCACCACTC 
TTCACGACCC CAGGCCACCT TCTGGATAAG TTCATCAAGG AGTTTCTCCA GCCCAACAAA 
TGCTTCCTAG AGCAGATTGA CAGTGCTGTT AACATCATCC GTACATTCCT TAAAGAAAAC 
TGCTTCCGAC AATCAACAGC CAAGATCCAG ATTGTCCGGG GAGGATCAAC CGCCAAAGGC 
ACAGCTCTGA AGACTGGCTC TGATGCCGAT CTCGTCGTGT TCCATAACTC ACTTAAAAGC 
TACACCTCCC AAAAAAACGA GCGGCACAAA ATCGTCAAGG AAATCCATGA ACAGCTGAAA 
GCCTTTTGGA GGGAGAAGGA GGAGGAGCTT GAAGTCAGCT TTGAGCCTCC CAAGTGGAAG 
GCTCCCAGGG TGCTGAGCTT CTCTCTGAAA TCCAAAGTCC TCAACGAAAG TGTCAGCTTT 
GATGTGCTTC CTGCCTTTAA TGCACTGGGT CAGCTGAGTT CTGGCTCCAC ACCCAGCCCC 
GAGGTTTATG CAGGGCTCAT TGATCTGTAT AAATCCTCGG ACCTCCCGGG AGGAGAGTTT 
TCTACCTGTT TCACAGTCCT GCAGCGAAAC TTCATTCGCT CCCGGCCCAC CAAACTAAAG 
GATTTAATTC GCCTGGTGAA GCACTGGTAC AAAGAGTGTG AAAGGAAACT GAAGCCAAAG 
GGGTCTTTGC CCCCAAAGTA TGCCTTGGAG CTGCTCACCA TCTATGCCTG GGAGCAGGGG 
AGTGGAGTGC CGGATTTTGA CACTGCAGAA GGTTTCCGGA CAGTCCTGGA GCTGGTCACA 
CAATATCAGC AGCTCTGCAT CTTCTGGAAG GTCAATTACA ACTTTGAAGA TGAGACCGTG 
AGGAAGTTTC TACTGAGCCA GTTGCAGAAA ACCAGGCCTG TGATCTTGGA CCCAGCCGAA 
CCCACAGGTG ACGTGGGTGG AGGGGACCGT TGGTGTTGGC ATCTTCTGGC AAAAGAAGCA 
AAGGAATGGT TATCCTCTCC CTGCTTCAAG GATGGGACTG GAAACCCAAT ACCACCTTGG 
AAAGTGCCGG TAAAAGTCAT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002526.2
CDS	91..2154
Translation	MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIGGSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEIQKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVCFTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILDPVDPTNNVSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPWKVPVKVI

Target ORF information:

RefSeq Version	NM_002535.3
Organism	Homo sapiens(human)
Definition	Homo sapiens 2'-5'-oligoadenylate synthetase 2 (OAS2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002535.3

ORF Insert Sequence:

ATGGGAAATG GGGAGTCCCA GCTGTCCTCG GTGCCTGCTC AGAAGCTGGG TTGGTTTATC 
CAGGAATACC TGAAGCCCTA CGAAGAATGT CAGACACTGA TCGACGAGAT GGTGAACACC 
ATCTGTGACG TCCTGCAGGA ACCCGAACAG TTCCCCCTGG TGCAGGGAGT GGCCATAGGT 
GGCTCCTATG GACGGAAAAC AGTCTTAAGA GGCAACTCCG ATGGTACCCT TGTCCTCTTC 
TTCAGTGACT TAAAACAATT CCAGGATCAG AAGAGAAGCC AACGTGACAT CCTCGATAAA 
ACTGGGGATA AGCTGAAGTT CTGTCTGTTC ACGAAGTGGT TGAAAAACAA TTTCGAGATC 
CAGAAGTCCC TTGATGGGTT CACCATCCAG GTGTTCACAA AAAATCAGAG AATCTCTTTC 
GAGGTGCTGG CCGCCTTCAA CGCTCTGAGC TTAAATGATA ATCCCAGCCC CTGGATCTAT 
CGAGAGCTCA AAAGATCCTT GGATAAGACA AATGCCAGTC CTGGTGAGTT TGCAGTCTGC 
TTCACTGAAC TCCAGCAGAA GTTTTTTGAC AACCGTCCTG GAAAACTAAA GGATTTGATC 
CTCTTGATAA AGCACTGGCA TCAACAGTGC CAGAAAAAAA TCAAGGATTT ACCCTCGCTG 
TCTCCGTATG CCCTGGAGCT GCTTACGGTG TATGCCTGGG AACAGGGGTG CAGAAAAGAC 
AACTTTGACA TTGCTGAAGG CGTCAGAACC GTACTGGAGC TGATCAAATG CCAGGAGAAG 
CTGTGTATCT ATTGGATGGT CAACTACAAC TTTGAAGATG AGACCATCAG GAACATCCTG 
CTGCACCAGC TCCAATCAGC GAGGCCAGTA ATCTTGGATC CAGTTGACCC AACCAATAAT 
GTGAGTGGAG ATAAAATATG CTGGCAATGG CTGAAAAAAG AAGCTCAAAC CTGGTTGACT 
TCTCCCAACC TGGATAATGA GTTACCTGCA CCATCTTGGA ATGTTCTGCC TGCACCACTC 
TTCACGACCC CAGGCCACCT TCTGGATAAG TTCATCAAGG AGTTTCTCCA GCCCAACAAA 
TGCTTCCTAG AGCAGATTGA CAGTGCTGTT AACATCATCC GTACATTCCT TAAAGAAAAC 
TGCTTCCGAC AATCAACAGC CAAGATCCAG ATTGTCCGGG GAGGATCAAC CGCCAAAGGC 
ACAGCTCTGA AGACTGGCTC TGATGCCGAT CTCGTCGTGT TCCATAACTC ACTTAAAAGC 
TACACCTCCC AAAAAAACGA GCGGCACAAA ATCGTCAAGG AAATCCATGA ACAGCTGAAA 
GCCTTTTGGA GGGAGAAGGA GGAGGAGCTT GAAGTCAGCT TTGAGCCTCC CAAGTGGAAG 
GCTCCCAGGG TGCTGAGCTT CTCTCTGAAA TCCAAAGTCC TCAACGAAAG TGTCAGCTTT 
GATGTGCTTC CTGCCTTTAA TGCACTGGGT CAGCTGAGTT CTGGCTCCAC ACCCAGCCCC 
GAGGTTTATG CAGGGCTCAT TGATCTGTAT AAATCCTCGG ACCTCCCGGG AGGAGAGTTT 
TCTACCTGTT TCACAGTCCT GCAGCGAAAC TTCATTCGCT CCCGGCCCAC CAAACTAAAG 
GATTTAATTC GCCTGGTGAA GCACTGGTAC AAAGAGTGTG AAAGGAAACT GAAGCCAAAG 
GGGTCTTTGC CCCCAAAGTA TGCCTTGGAG CTGCTCACCA TCTATGCCTG GGAGCAGGGG 
AGTGGAGTGC CGGATTTTGA CACTGCAGAA GGTTTCCGGA CAGTCCTGGA GCTGGTCACA 
CAATATCAGC AGCTCTGCAT CTTCTGGAAG GTCAATTACA ACTTTGAAGA TGAGACCGTG 
AGGAAGTTTC TACTGAGCCA GTTGCAGAAA ACCAGGCCTG TGATCTTGGA CCCAGCCGAA 
CCCACAGGTG ACGTGGGTGG AGGGGACCGT TGGTGTTGGC ATCTTCTGGC AAAAGAAGCA 
AAGGAATGGT TATCCTCTCC CTGCTTCAAG GATGGGACTG GAAACCCAAT ACCACCTTGG 
AAAGTGCCGG TAAAAGTCAT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mx1, OAS1 and OAS2 polymorphisms are associated with the severity of liver disease in HIV/HCV-coinfected patients: A cross-sectional study.
Scientific reports741516(2017 Jan)
Garc?a-?lvarez M,Berenguer J,Jim?nez-Sousa MA,Pineda-Tenor D,Ald?miz-Echevarria T,Tejerina F,Diez C,V?zquez-Mor?n S,Resino S

Adaptively introgressed Neandertal haplotype at the OAS locus functionally impacts innate immune responses in humans.
Genome biology17(1)246(2016 Nov)
Sams AJ,Dumaine A,N?d?lec Y,Yotova V,Alfieri C,Tanner JE,Messer PW,Barreiro LB

Epigenetic regulation of OAS2 shows disease-specific DNA methylation profiles at individual CpG sites.
Scientific reports632579(2016 Aug)
Gu X,Boldrup L,Coates PJ,Fahraeus R,Nylander E,Loizou C,Olofsson K,Norberg-Spaak L,G?rskog O,Nylander K

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OAS2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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