Kir3dl1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kir3dl1
Entrez Gene ID	245616
Full Name	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
Synonyms	Kirl1,Kirl2,Krl1
General protein information	Preferred Names killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 Names killer cell immunoglobulin-like receptor 3DL1 KIR-like receptor 1 killer cell immunoglobulin-like receptor Kir3dl1 killer immunoglobulin receptor-like protein 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: X Map Location: X F1\|X 58.77 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_001310690.1	NP_001297619.1	killer cell immunoglobulin-like receptor 3DL1 isoform 2 precursor
NM_177749.4	NP_808417.2	killer cell immunoglobulin-like receptor 3DL1 isoform 1 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	KIR3DL3	NP_703144.2
Mus musculus (house mouse)	Kir3dl1	NP_808417.2
	KIR3DL2	NP_001098022.1
Rattus norvegicus (Norway rat)	Kir3dl1	NP_852144.1
Pan troglodytes (chimpanzee)	KIR3DL3	XP_003316727.1
Mus musculus (house mouse)	Kir3dl2	NP_808416.1

Gene Ontology
Bibliography

Related articles in PubMed

Killer cell Ig-like receptor (KIR) 3DL1 down-regulation enhances inhibition of type 1 diabetes by autoantigen-specific regulatory T cells.
Qin H, Wang Z, Du W, Lee WH, Wu X, Riggs AD, Liu CP
Proceedings of the National Academy of Sciences of the United States of America108(5)2016-21(2011 Feb)

Expression of murine killer immunoglobulin-like receptor KIRL1 on CD1d-independent NK1.1(+) T cells.
Wilson EB, Parachoniak CA, Carpenito C, Mager DL, Takei F
Immunogenetics59(8)641-51(2007 Aug)

Expression of a killer cell receptor-like gene in plastic regions of the central nervous system.
Bryceson YT, Foster JA, Kuppusamy SP, Herkenham M, Long EO
Journal of neuroimmunology161(1-2)177-82(2005 Apr)

Cutting edge: molecular cloning of a killer cell Ig-like receptor in the mouse and rat.
Hoelsbrekken SE, Nylenna ?, Saether PC, Slettedal IO, Ryan JC, Fossum S, Dissen E
Journal of immunology (Baltimore, Md. : 1950)170(5)2259-63(2003 Mar)

Identification of the mouse killer immunoglobulin-like receptor-like (Kirl) gene family mapping to chromosome X.
Welch AY, Kasahara M, Spain LM
Immunogenetics54(11)782-90(2003 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

studies indicate that KIR3DL1 expression may negatively regulate Treg function and suggest a previously undescribed target for improving immune tolerance for potential treatment of autoimmune diseases like IDDM
Title: Killer cell Ig-like receptor (KIR) 3DL1 down-regulation enhances inhibition of type 1 diabetes by autoantigen-specific regulatory T cells.

cloned Kir cDNAs from multiple strains of mice. Sequencing of the cDNA clones showed that the Kir3dl1 gene is found in C3H/HeJ and CBA/J but not in B6 mice.
Title: Expression of murine killer immunoglobulin-like receptor KIRL1 on CD1d-independent NK1.1(+) T cells.

Selective expression of killer cell immunoglobulin-like receptor (KIR) genes in subregions of the mouse brain where synaptic plasticity and neurogenesis occur, including olfactory bulbs, rostral migratory stream and dentate gyrus of hippocampus.
Title: Expression of a killer cell receptor-like gene in plastic regions of the central nervous system.

first close rodent homologue of the NK receptor KIR family; shares 40% amino acid identity with primate KIR family members
Title: Identification of the mouse killer immunoglobulin-like receptor-like (Kirl) gene family mapping to chromosome X.

The following Kir3dl1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kir3dl1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu58172	NM_177749.4 Latest version!	Mus musculus killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 (Kir3dl1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu74237	NM_001310690.1 Latest version!	Mus musculus killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 (Kir3dl1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kir3dl1 ( NM_177749.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_808417.2 Mus musculus killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 (Kir3dl1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu58172
Clone ID Related Accession (Same CDS sequence)	NM_177749.4
Accession Version	NM_177749.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1230bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Mus musculus(house mouse)
Product	killer cell immunoglobulin-like receptor 3DL1 isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY152727.1 and AY530782.1. On Jul 17, 2015 this sequence version replaced NM_177749.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1). ##Evidence-Data-START## Transcript exon combination :: AY530782.1, AY130461.1 [ECO:0000332] ##Evidence-Data-END##

ATGCTGCTCT GGTTCCTCAG CCTCGTGTGT TCTGGTTTCT TCCTAGTCCA GAGGATGTCA 
GCACACTTGG GAAGCCATGA TAAACCATTC CTATCTGCCT GGCCAAGTTA TGTTGTTCCT 
CTGGGACAGA ATGTGACTCT TACATGTGAC TCTCATAGAG GATCTAACAT ATTCAAGCTG 
TACAAAGAAG AAGGGTCTCC AAACCATCAG TTACATGAGA CTACATTTCA GAAGAGCCAG 
GTCTTTGGTC CTGTGACAAC AGAACATGCA GGAACCTACA GATGCTTCCA TCCTCAATAT 
GCTAATGTAT TGTCAGCACA TAGTGAGCCT CTGAAAATCA TAATTTCAGG AATCTACATG 
AAGCCTTTCC TCTTGATTCT ACAAAGTCCC CTGGTGGATA CAGGAGGGAA TGTGACCCTG 
GAATGTCACT CAGAGAATAT GTTCGATACA TACATTTTGA TTTCACACAG AATGGGAATA 
ATCAAGAACT CTGTCCAAGT TTCTGCAGAA CATCATGAAA GTGGGTCACA TGTCAGCTAC 
TCAATAGGTC CCATGACACC TGACCTTGTT GGGACTTACA CATGCTATGG TGCTAACAGT 
TACTACCCCT ATGAATGGTC AGACTCCAGT GACCCCATTG ACATCAAGAT CACAGGTATA 
TACAAGAAAC CTTCTCTGTC AGCCCTGATG GGCCCTGTGC TGATGATGTC AGGAGAGACC 
ATGACCCTGT CTTGCATCTC TGACCATCAG TTTGACACGT TCCATATGTC CAGGGAAGGG 
GTGCCTCGGG GACAGGGGAT GCCTGCAGTG CAGAGCCACA GTGGTAAATT CGAGGCAAAA 
TTCCTTCTTA GTCCAATGAT CCAAAAAGGG AACTATAGAT GCTATGGCTC TTTCAGGAAC 
GCTTCCCATG TGTGGTCCTC CCCAAGTGAC CCCTTGTACC TTCCTGCCAA AGGAAACTGT 
CCTGCATACA CAGAAGCAGA TACCAAAACA AATAACTACA AGAACCTGCA CATTCTAACT 
GGGCTCTTAG TAACCATGGT CCTTGTCGTC ATCATCATCT TTTACTCTTG TTACTTCTCC 
AAACAGAATA AGTCTCAGAA ACAAGCAGCA GCCAGCATGG AACAAGAGTA TGAAGTTAAA 
AACACAATAA ACACACAGGA CTTTGAAAGA CAAGAAGGAC AGGGGTTACA TACACAGAAC 
TTGAGCAGAG AATCTTCAAC CAAAACTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_808417.2
CDS	33..1262
Translation	MLLWFLSLVCSGFFLVQRMSAHLGSHDKPFLSAWPSYVVPLGQNVTLTCDSHRGSNIFKLYKEEGSPNHQLHETTFQKSQVFGPVTTEHAGTYRCFHPQYANVLSAHSEPLKIIISGIYMKPFLLILQSPLVDTGGNVTLECHSENMFDTYILISHRMGIIKNSVQVSAEHHESGSHVSYSIGPMTPDLVGTYTCYGANSYYPYEWSDSSDPIDIKITGIYKKPSLSALMGPVLMMSGETMTLSCISDHQFDTFHMSREGVPRGQGMPAVQSHSGKFEAKFLLSPMIQKGNYRCYGSFRNASHVWSSPSDPLYLPAKGNCPAYTEADTKTNNYKNLHILTGLLVTMVLVVIIIFYSCYFSKQNKSQKQAAASMEQEYEVKNTINTQDFERQEGQGLHTQNLSRESSTKT

Target ORF information:

RefSeq Version	NM_177749.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 (Kir3dl1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_177749.4

ORF Insert Sequence:

ATGCTGCTCT GGTTCCTCAG CCTCGTGTGT TCTGGTTTCT TCCTAGTCCA GAGGATGTCA 
GCACACTTGG GAAGCCATGA TAAACCATTC CTATCTGCCT GGCCAAGTTA TGTTGTTCCT 
CTGGGACAGA ATGTGACTCT TACATGTGAC TCTCATAGAG GATCTAACAT ATTCAAGCTG 
TACAAAGAAG AAGGGTCTCC AAACCATCAG TTACATGAGA CTACATTTCA GAAGAGCCAG 
GTCTTTGGTC CTGTGACAAC AGAACATGCA GGAACCTACA GATGCTTCCA TCCTCAATAT 
GCTAATGTAT TGTCAGCACA TAGTGAGCCT CTGAAAATCA TAATTTCAGG AATCTACATG 
AAGCCTTTCC TCTTGATTCT ACAAAGTCCC CTGGTGGATA CAGGAGGGAA TGTGACCCTG 
GAATGTCACT CAGAGAATAT GTTCGATACA TACATTTTGA TTTCACACAG AATGGGAATA 
ATCAAGAACT CTGTCCAAGT TTCTGCAGAA CATCATGAAA GTGGGTCACA TGTCAGCTAC 
TCAATAGGTC CCATGACACC TGACCTTGTT GGGACTTACA CATGCTATGG TGCTAACAGT 
TACTACCCCT ATGAATGGTC AGACTCCAGT GACCCCATTG ACATCAAGAT CACAGGTATA 
TACAAGAAAC CTTCTCTGTC AGCCCTGATG GGCCCTGTGC TGATGATGTC AGGAGAGACC 
ATGACCCTGT CTTGCATCTC TGACCATCAG TTTGACACGT TCCATATGTC CAGGGAAGGG 
GTGCCTCGGG GACAGGGGAT GCCTGCAGTG CAGAGCCACA GTGGTAAATT CGAGGCAAAA 
TTCCTTCTTA GTCCAATGAT CCAAAAAGGG AACTATAGAT GCTATGGCTC TTTCAGGAAC 
GCTTCCCATG TGTGGTCCTC CCCAAGTGAC CCCTTGTACC TTCCTGCCAA AGGAAACTGT 
CCTGCATACA CAGAAGCAGA TACCAAAACA AATAACTACA AGAACCTGCA CATTCTAACT 
GGGCTCTTAG TAACCATGGT CCTTGTCGTC ATCATCATCT TTTACTCTTG TTACTTCTCC 
AAACAGAATA AGTCTCAGAA ACAAGCAGCA GCCAGCATGG AACAAGAGTA TGAAGTTAAA 
AACACAATAA ACACACAGGA CTTTGAAAGA CAAGAAGGAC AGGGGTTACA TACACAGAAC 
TTGAGCAGAG AATCTTCAAC CAAAACTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kir3dl1 ( NM_001310690.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001297619.1 Mus musculus killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 (Kir3dl1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu74237
Clone ID Related Accession (Same CDS sequence)	NM_001310690.1
Accession Version	NM_001310690.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 951bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Mus musculus(house mouse)
Product	killer cell immunoglobulin-like receptor 3DL1 isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY152727.1, AL672068.13 and AY530782.1. On Jul 17, 2015 this sequence version replaced XM_011247741.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. It encodes isoform 2 which is shorter than isoform 1. ##Evidence-Data-START## Transcript exon combination :: AY152727.1 [ECO:0000332] ##Evidence-Data-END##

ATGCTGCTCT GGTTCCTCAG CCTCGTGTGT TCTGGTTTCT TCCTAGTCCA GAGGATGTCA 
GCACACTTGG GAATCTACAT GAAGCCTTTC CTCTTGATTC TACAAAGTCC CCTGGTGGAT 
ACAGGAGGGA ATGTGACCCT GGAATGTCAC TCAGAGAATA TGTTCGATAC ATACATTTTG 
ATTTCACACA GAATGGGAAT AATCAAGAAC TCTGTCCAAG TTTCTGCAGA ACATCATGAA 
AGTGGGTCAC ATGTCAGCTA CTCAATAGGT CCCATGACAC CTGACCTTGT TGGGACTTAC 
ACATGCTATG GTGCTAACAG TTACTACCCC TATGAATGGT CAGACTCCAG TGACCCCATT 
GACATCAAGA TCACAGGTAT ATACAAGAAA CCTTCTCTGT CAGCCCTGAT GGGCCCTGTG 
CTGATGATGT CAGGAGAGAC CATGACCCTG TCTTGCATCT CTGACCATCA GTTTGACACG 
TTCCATATGT CCAGGGAAGG GGTGCCTCGG GGACAGGGGA TGCCTGCAGT GCAGAGCCAC 
AGTGGTAAAT TCGAGGCAAA ATTCCTTCTT AGTCCAATGA TCCAAAAAGG GAACTATAGA 
TGCTATGGCT CTTTCAGGAA CGCTTCCCAT GTGTGGTCCT CCCCAAGTGA CCCCTTGTAC 
CTTCCTGCCA AAGGAAACTG TCCTGCATAC ACAGAAGCAG ATACCAAAAC AAATAACTAC 
AAGAACCTGC ACATTCTAAC TGGGCTCTTA GTAACCATGG TCCTTGTCGT CATCATCATC 
TTTTACTCTT GTTACTTCTC CAAACAGAAT AAGTCTCAGA AACAAGCAGC AGCCAGCATG 
GAACAAGAGT ATGAAGTTAA AAACACAATA AACACACAGG ACTTTGAAAG ACAAGAAGGA 
CAGGGGTTAC ATACACAGAA CTTGAGCAGA GAATCTTCAA CCAAAACTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001297619.1
CDS	33..983
Translation	MLLWFLSLVCSGFFLVQRMSAHLGIYMKPFLLILQSPLVDTGGNVTLECHSENMFDTYILISHRMGIIKNSVQVSAEHHESGSHVSYSIGPMTPDLVGTYTCYGANSYYPYEWSDSSDPIDIKITGIYKKPSLSALMGPVLMMSGETMTLSCISDHQFDTFHMSREGVPRGQGMPAVQSHSGKFEAKFLLSPMIQKGNYRCYGSFRNASHVWSSPSDPLYLPAKGNCPAYTEADTKTNNYKNLHILTGLLVTMVLVVIIIFYSCYFSKQNKSQKQAAASMEQEYEVKNTINTQDFERQEGQGLHTQNLSRESSTKT

Target ORF information:

RefSeq Version	NM_001310690.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 (Kir3dl1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001310690.1

ORF Insert Sequence:

ATGCTGCTCT GGTTCCTCAG CCTCGTGTGT TCTGGTTTCT TCCTAGTCCA GAGGATGTCA 
GCACACTTGG GAATCTACAT GAAGCCTTTC CTCTTGATTC TACAAAGTCC CCTGGTGGAT 
ACAGGAGGGA ATGTGACCCT GGAATGTCAC TCAGAGAATA TGTTCGATAC ATACATTTTG 
ATTTCACACA GAATGGGAAT AATCAAGAAC TCTGTCCAAG TTTCTGCAGA ACATCATGAA 
AGTGGGTCAC ATGTCAGCTA CTCAATAGGT CCCATGACAC CTGACCTTGT TGGGACTTAC 
ACATGCTATG GTGCTAACAG TTACTACCCC TATGAATGGT CAGACTCCAG TGACCCCATT 
GACATCAAGA TCACAGGTAT ATACAAGAAA CCTTCTCTGT CAGCCCTGAT GGGCCCTGTG 
CTGATGATGT CAGGAGAGAC CATGACCCTG TCTTGCATCT CTGACCATCA GTTTGACACG 
TTCCATATGT CCAGGGAAGG GGTGCCTCGG GGACAGGGGA TGCCTGCAGT GCAGAGCCAC 
AGTGGTAAAT TCGAGGCAAA ATTCCTTCTT AGTCCAATGA TCCAAAAAGG GAACTATAGA 
TGCTATGGCT CTTTCAGGAA CGCTTCCCAT GTGTGGTCCT CCCCAAGTGA CCCCTTGTAC 
CTTCCTGCCA AAGGAAACTG TCCTGCATAC ACAGAAGCAG ATACCAAAAC AAATAACTAC 
AAGAACCTGC ACATTCTAAC TGGGCTCTTA GTAACCATGG TCCTTGTCGT CATCATCATC 
TTTTACTCTT GTTACTTCTC CAAACAGAAT AAGTCTCAGA AACAAGCAGC AGCCAGCATG 
GAACAAGAGT ATGAAGTTAA AAACACAATA AACACACAGG ACTTTGAAAG ACAAGAAGGA 
CAGGGGTTAC ATACACAGAA CTTGAGCAGA GAATCTTCAA CCAAAACTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Killer cell Ig-like receptor (KIR) 3DL1 down-regulation enhances inhibition of type 1 diabetes by autoantigen-specific regulatory T cells.
Proceedings of the National Academy of Sciences of the United States of America108(5)2016-21(2011 Feb)
Qin H,Wang Z,Du W,Lee WH,Wu X,Riggs AD,Liu CP

Expression of murine killer immunoglobulin-like receptor KIRL1 on CD1d-independent NK1.1(+) T cells.
Immunogenetics59(8)641-51(2007 Aug)
Wilson EB,Parachoniak CA,Carpenito C,Mager DL,Takei F

Expression of a killer cell receptor-like gene in plastic regions of the central nervous system.
Journal of neuroimmunology161(1-2)177-82(2005 Apr)
Bryceson YT,Foster JA,Kuppusamy SP,Herkenham M,Long EO

Cutting edge: molecular cloning of a killer cell Ig-like receptor in the mouse and rat.
Journal of immunology (Baltimore, Md. : 1950)170(5)2259-63(2003 Mar)
Hoelsbrekken SE,Nylenna ?,Saether PC,Slettedal IO,Ryan JC,Fossum S,Dissen E

Identification of the mouse killer immunoglobulin-like receptor-like (Kirl) gene family mapping to chromosome X.
Immunogenetics54(11)782-90(2003 Feb)
Welch AY,Kasahara M,Spain LM

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Kir3dl1 cDNA ORF clone, Mus musculus(house mouse)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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