The following Synm gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Synm cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu09624 | |
| Clone ID Related Accession (Same CDS sequence) | NM_201639.2 | |
| Accession Version | NM_201639.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4686bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-02 | |
| Organism | Mus musculus(house mouse) | |
| Product | synemin isoform H | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK143019.1 and AC158296.6. On Jul 25, 2007 this sequence version replaced NM_201639.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (H). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ579700.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164133 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGCTGTCCT GGCGGCTGCA GACGGGCTCT GAAAAGGCGG AGCTGCAGGA GCTCAACGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_964001.2 |
| CDS | 115..4800 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_201639.2 |
1 | ATGCTGTCCT GGCGGCTGCA GACGGGCTCT GAAAAGGCGG AGCTGCAGGA GCTCAACGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu10105 | |
| Clone ID Related Accession (Same CDS sequence) | NM_207663.3 | |
| Accession Version | NM_207663.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3780bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-02 | |
| Organism | Mus musculus(house mouse) | |
| Product | synemin isoform M | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK143019.1 and AC158296.6. On Jul 25, 2007 this sequence version replaced NM_207663.2. Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, compared to variant 1, that results in a shorter protein (isoform M), compared to isoform H. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ579701.1, AK143019.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## | |
1 | ATGCTGTCCT GGCGGCTGCA GACGGGCTCT GAAAAGGCGG AGCTGCAGGA GCTCAACGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_997546.2 |
| CDS | 115..3894 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_207663.3 |
1 | ATGCTGTCCT GGCGGCTGCA GACGGGCTCT GAAAAGGCGG AGCTGCAGGA GCTCAACGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu58365 | |
| Clone ID Related Accession (Same CDS sequence) | NM_183312.3 | |
| Accession Version | NM_183312.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1116bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-02 | |
| Organism | Mus musculus(house mouse) | |
| Product | synemin isoform L | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK143019.1 and AC158296.6. On Jul 25, 2007 this sequence version replaced NM_183312.2. Transcript Variant: This variant (3) uses an alternate splice site in the 3' coding region that results in a frameshift and early stop codon, compared to variant 1. The encoded protein (isoform L) has a shorter and distinct C-terminus, compared to isoform H. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ579702.1 [ECO:0000332] ##Evidence-Data-END## | |
1 | ATGCTGTCCT GGCGGCTGCA GACGGGCTCT GAAAAGGCGG AGCTGCAGGA GCTCAACGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_899135.3 |
| CDS | 115..1230 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_183312.3 |
1 | ATGCTGTCCT GGCGGCTGCA GACGGGCTCT GAAAAGGCGG AGCTGCAGGA GCTCAACGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Absence of synemin in mice causes structural and functional abnormalities in heart. |
Vimentin knockout results in increased expression of sub-endothelial basement membrane components and carotid stiffness in mice. |
Deficiency of the intermediate filament synemin reduces bone mass in vivo. |
High-throughput discovery of novel developmental phenotypes. |
Myopathic changes in murine skeletal muscle lacking synemin. |
