SYNM cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SYNM
Entrez Gene ID	23336
Full Name	synemin
Synonyms	DMN,SYN
General protein information	Preferred Names synemin Names synemin desmuslin synemin alpha synemin beta synemin, intermediate filament protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q26.3
Summary	The protein encoded by this gene is an intermediate filament (IF) family member. IF proteins are cytoskeletal proteins that confer resistance to mechanical stress and are encoded by a dispersed multigene family. This protein has been found to form a linkage between desmin, which is a subunit of the IF network, and the extracellular matrix, and provides an important structural support in muscle. Two alternatively spliced variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	606087

mRNA and Protein(s)

mRNA	Protein	Name
NM_145728.2	NP_663780.2	synemin isoform A
NM_015286.6	NP_056101.5	synemin isoform B
XM_017022035.1	XP_016877524.1	synemin isoform X1
NM_015286.5	NP_056101.5	synemin isoform B
NM_145728.3	NP_663780.2	synemin isoform A

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SYNM	XP_003314921.1
	SYNM	XP_001108469.2
Homo sapiens (human)	SYNM	NP_663780.2
Bos taurus (cattle)	SYNM	NP_001178382.1
Danio rerio (zebrafish)	synm	XP_005159213.1
Rattus norvegicus (Norway rat)	Synm	NP_001128330.1
Xenopus tropicalis (tropical clawed frog)	synm	XP_002939315.2
Mus musculus (house mouse)	Synm	NP_964001.2
Gallus gallus (chicken)	SYNM	NP_990140.1

Gene Ontology
Bibliography

Related articles in PubMed

Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM.
Perisic Matic L, Rykaczewska U, Razuvaev A, Sabater-Lleal M, Lengquist M, Miller CL, Ericsson I, R?hl S, Kronqvist M, Aldi S, Magn? J, Paloschi V, Vesterlund M, Li Y, Jin H, Diez MG, Roy J, Baldassarre D, Veglia F, Humphries SE, de Faire U, Tremoli E, Odeberg J, Vukojevi? V, Lehti? J, Maegdefessel L, Ehrenborg E, Paulsson-Berne G, Hansson GK, Lindeman JH, Eriksson P, Quertermous T, Hamsten A, Hedin U
Arteriosclerosis, thrombosis, and vascular biology36(9)1947-61(2016 Sep)

?-Synemin localizes to the M-band of the sarcomere through interaction with the M10 region of titin.
Prudner BC, Roy PS, Damron DS, Russell MA
FEBS letters588(24)4625-30(2014 Dec)

Synemin is expressed in reactive astrocytes and Rosenthal fibers in Alexander disease.
Pekny T, Faiz M, Wilhelmsson U, Curtis MA, Matej R, Skalli O, Pekny M
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica122(1)76-80(2014 Jan)

Synemin promotes AKT-dependent glioblastoma cell proliferation by antagonizing PP2A.
Pitre A, Davis N, Paul M, Orr AW, Skalli O
Molecular biology of the cell23(7)1243-53(2012 Apr)

Synemin down-regulation in human hepatocellular carcinoma does not destabilize cytoskeletons in vivo.
Liu YH, Cheng CC, Lai YS, Chao WT, Pei RJ, Hsu YH, Ho CC
Biochemical and biophysical research communications404(1)488-93(2011 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

LMOD1, SYNPO2, PDLIM7, PLN, and SYNM down-regulation reflect the altered phenotype of smooth muscle cells in vascular disease and could be early sensitive markers of SMC dedifferentiation.
Title: Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM.

alpha-Synemin localizes to the M-band of the sarcomere through interaction with the M10 region of titin
Title: ?-Synemin localizes to the M-band of the sarcomere through interaction with the M10 region of titin.

Immunohistochemistry of synemin in reactive astrocytes and Rosenthal fibers in two patients with Alexander disease. There was an abundance of GFAP-positive Rosenthal fibers and widespread reactive gliosis in the white matter and subpial regions.
Title: Synemin is expressed in reactive astrocytes and Rosenthal fibers in Alexander disease.

synemin positively regulates glioblastoma cell proliferation by helping sequester PP2A away from Akt, thereby favoring Akt activation.
Title: Synemin promotes AKT-dependent glioblastoma cell proliferation by antagonizing PP2A.

Synemin knock-down did not influence the cytoskeleton expression and organization of human Chang liver cells
Title: Synemin down-regulation in human hepatocellular carcinoma does not destabilize cytoskeletons in vivo.

The following SYNM gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SYNM cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu08894	NM_015286.6 Latest version!	Homo sapiens synemin (SYNM), transcript variant B, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$888.30 $1269.00
OHu18579	NM_145728.3 Latest version!	Homo sapiens synemin (SYNM), transcript variant A, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$384.30 $549.00
OHu85326	XM_017022035.1 Latest version!	Homo sapiens synemin (SYNM), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$643.30 $919.00
View Old Accession Versions >>
OHu08894	NM_015286.5	Homo sapiens synemin (SYNM), transcript variant B, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$888.30 $1269.00
OHu18579	NM_145728.2	Homo sapiens synemin (SYNM), transcript variant A, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$384.30 $549.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SYNM ( NM_015286.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_056101.5 Homo sapiens synemin (SYNM), transcript variant B, mRNA.

Price & Availability↑

CloneID	OHu08894
Clone ID Related Accession (Same CDS sequence)	NM_015286.6 , NM_015286.5
Accession Version	NM_015286.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-18
Organism	Homo sapiens(human)
Product	synemin isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB002351.2, AW292788.1 and AC036108.19. On Jun 1, 2019 this sequence version replaced NM_015286.5. Transcript Variant: This variant (B) lacks an internal segment of the coding region, compared to variant A. It maintains the reading frame and encodes a shorter isoform (B), compared to isoform A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ310521.1, SRR1660803.149476.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGTCCT GGCGGCTGCA GACGGGCCCC GAGAAGGCCG AGCTCCAGGA GCTCAACGCC 
CGGCTCTATG ACTACGTGTG TCGGGTGCGG GAGCTGGAGC GCGAAAACCT ACTCCTGGAG 
GAGGAGCTGC GCGGCCGGCG CGGGCGAGAG GGCCTGTGGG CCGAGGGGCA GGCCCGCTGC 
GCCGAGGAGG CGCGCAGCTT GCGGCAGCAG CTGGACGAGC TGAGCTGGGC CACTGCGCTG 
GCGGAGGGCG AGCGGGACGC TCTGCGGCGC GAGCTGCGGG AGCTGCAGCG CCTGGATGCG 
GAGGAGCGCG CCGCCCGCGG CCGCCTGGAC GCCGAGCTGG GTGCGCAGCA GCGCGAGCTG 
CAGGAGGCGC TGGGCGCGCG CGCCGCCCTC GAGGCGCTGC TGGGCCGGCT GCAGGCCGAG 
CGCCGAGGCC TCGACGCGGC CCACGAACGC GACGTGAGGG AGCTGCGCGC GCGCGCCGCC 
AGCCTTACCA TGCATTTCCG CGCCCGCGCC ACCGGCCCCG CCGCGCCGCC GCCACGCCTG 
CGGGAGGTGC ACGACAGCTA CGCACTGCTG GTGGCCGAGT CGTGGCGGGA GACGGTGCAG 
CTGTACGAGG ACGAGGTGCG CGAGCTGGAG GAGGCGCTGC GGCGCGGCCA GGAGAGCAGA 
CTCCAGGCGG AGGAAGAGAC GCGGCTGTGC GCGCAGGAGG CAGAGGCGCT GCGGCGCGAG 
GCGCTCGGGT TGGAGCAGCT GCGCGCGCGG CTGGAGGACG CGCTGCTGCG GATGCGCGAG 
GAGTACGGGA TACAGGCCGA GGAGCGGCAG AGAGTGATTG ACTGCCTGGA GGATGAGAAG 
GCAACCCTCA CCTTGGCCAT GGCTGACTGG CTGCGGGACT ATCAGGACCT CCTGCAGGTG 
AAGACCGGCC TCAGTCTGGA GGTGGCGACC TACCGGGCCT TATTGGAAGG AGAAAGTAAT 
CCAGAGATAG TGATCTGGGC TGAGCACGTT GAAAACATGC CGTCAGAATT CAGAAACAAA 
TCCTATCACT ATACCGACTC ACTACTACAG AGGGAAAATG AAAGGAATCT ATTTTCAAGG 
CAGAAAGCAC CTTTGGCAAG TTTCAATCAC AGCTCGGCAC TGTATTCTAA CCTGTCAGGG 
CACCGTGGAT CTCAGACGGG CACATCTATT GGAGGTGATG CCAGAAGAGG CTTCTTGGGC 
TCGGGATATT CTTCCTCGGC CACTACCCAG CAGGAAAACT CATACGGAAA AGCCGTCAGC 
AGTCAAACCA ACGTCAGAAC TTTCTCTCCA ACCTATGGCC TTTTAAGAAA TACTGAGGCT 
CAAGTGAAAA CATTCCCTGA CAGACCAAAA GCCGGAGATA CAAGGGAGGT CCCCGTTTAC 
ATAGGTGAAG ATTCCACAAT TGCCCGCGAG TCGTACCGGG ATCGCCGAGA CAAGGTGGCA 
GCAGGTGCTT CGGAAAGCAC ACGGTCAAAT GAGAGGACCG TCATTCTGGG AAAGAAAACA 
GAAGTGAAAG CCACGAGGGA GCAAGAAAGA AACAGACCAG AAACCATCCG AACAAAGCCA 
GAAGAGAAAA TGTTCGATTC TAAAGAGAAG GCTTCCGAGG AGAGAAACCT AAGATGGGAA 
GAATTGACAA AGTTAGATAA GGAAGCGAGA CAGAGAGAAA GCCAGCAGAT GAAGGAGAAG 
GCTAAGGAGA AGGACTCACC GAAGGAGAAG AGCGTGCGAG AGAGAGAGGT GCCGATTAGT 
CTAGAAGTAT CCCAGGACAG AAGAGCAGAG GTGTCCCCGA AAGGTTTGCA GACGCCTGTG 
AAGGATGCTG GTGGTGGGAC CGGTAGAGAG GCAGAAGCAA GAGAGCTACG GTTCAGGTTG 
GGCACCAGTG ATGCCACTGG TTCTCTGCAA GGCGATTCCA TGACAGAAAC CGTAGCAGAA 
AACATCGTTA CCAGTATCCT GAAGCAGTTC ACTCAGTCTC CAGAGACAGA AGCATCTGCT 
GATTCTTTTC CAGACACAAA AGTCACTTAC GTGGACAGGA AAGAGCTTCC TGGGGAAAGG 
AAAACAAAGA CTGAAATAGT TGTGGAGTCT AAACTGACTG AGGATGTTGA TGTTTCCGAT 
GAAGCTGGCC TGGACTACCT TTTAAGCAAG GATATTAAGG AAGTGGGGCT GAAAGGCAAG 
TCAGCCGAGC AGATGATAGG AGACATCATC AACCTCGGCC TGAAAGGGAG GGAGGGGAGA 
GCAAAGGTCG TCAACGTGGA GATCGTGGAG GAGCCCGTGA GTTATGTCAG CGGGGAGAAG 
CCGGAGGAGT TTTCCGTCCC ATTCAAAGTG GAGGAGGTCG AAGATGTGTC GCCAGGCCCC 
TGGGGGTTGG TTAAGGAGGA GGAAGGTTAT GGAGAAAGCG ATGTCACATT CTCAGTTAAT 
CAGCATCGAA GGACCAAGCA GCCTCAGGAG AACACGACTC ACGTGGAAGA AGTGACAGAG 
GCAGGTGATT CAGAGGGCGA GCAGAGTTAT TTTGTGTCCA CTCCAGATGA ACACCCCGGG 
GGGCACGACA GAGATGACGG CTCGGTGTAC GGGCAGATCC ACATCGAGGA GGAATCCACC 
ATCAGGTACT CTTGGCAGGA TGAAATCGTG CAGGGGACTC GAAGGAGGAC ACAGAAGGAC 
GGTGCAGTGG GCGAGAAGGT TGTGAAGCCC TTGGATGTCC CAGCGCCCTC TCTGGAGGGG 
GACCTGGGTT CCACTCACTG GAAAGAACAA GCTAGAAGCG GTGAATTTCA TGCCGAACCC 
ACAGTCATTG AAAAAGAAAT TAAAATACCC CACGAATTCC ACACCTCCAT GAAGGGCATC 
TCCTCCAAGG AGCCCCGGCA GCAGCTGGTG GAGGTCATCG GGCAGCTGGA GGAAACCCTT 
CCCGAGCGCA TGAGGGAGGA GCTGTCCGCC CTCACCAGAG AGGGGCAGGG TGGGCCGGGG 
AGCGTTTCCG TGGATGTCAA GAAGGTCCAG GGTGCTGGTG GCAGTTCCGT GACCCTGGTT 
GCTGAAGTCA ACGTCTCACA AACTGTGGAT GCCGATCGGT TAGACCTGGA GGAGCTGAGC 
AAAGATGAGG CCAGTGAGAT GGAGAAGGCT GTGGAGTCGG TGGTTCGGGA GAGCCTGAGC 
AGGCAACGCA GCCCAGCGCC TGGCAGCCCA GATGAGGAAG GTGGAGCGGA GGCCCCGGCT 
GCTGGCATTC GCTTTAGGCG TTGGGCCACC CGGGAGCTGT ACATCCCTTC AGGCGAGAGC 
GAGGTTGCTG GTGGGGCCTC TCACAGCTCG GGACAGCGCA CTCCCCAGGG CCCAGTGTCG 
GCCACTGTGG AGGTCAGCAG CCCCACAGGC TTTGCCCAGT CACAGGTGCT GGAGGATGTG 
AGCCAGGCTG CAAGGCACAT AAAACTCGGC CCCTCTGAAG TCTGGAGGAC TGAGCGAATG 
TCATATGAAG GACCCACTGC AGAAGTGGTG GAGATGGATG TGAGTAACGT AGAGGCGATC 
CGCAGCCGGA CACAGGAAGC GGGAGCTCTC GGTGTGTCTG ACCGTGGTTC CTGGAGAGAC 
GCGGACAGTA GGAATGACCA GGCAGTTGGT GTGAGCTTTA AGGCCTCTGC TGGGGAAGGA 
GACCAGGCCC ACAGAGAACA GGGCAAGGAG CAGGCCATGT TTGATAAGAA GGTGCAGCTC 
CAGAGAATGG TAGACCAAAG GTCGGTGATT TCAGATGAAA AGAAAGTTGC CCTCCTCTAT 
CTAGACAATG AGGAGGAGGA GAATGATGGG CATTGGTTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056101.5
CDS	121..3882
Translation	MLSWRLQTGPEKAELQELNARLYDYVCRVRELERENLLLEEELRGRRGREGLWAEGQARCAEEARSLRQQLDELSWATALAEGERDALRRELRELQRLDAEERAARGRLDAELGAQQRELQEALGARAALEALLGRLQAERRGLDAAHERDVRELRARAASLTMHFRARATGPAAPPPRLREVHDSYALLVAESWRETVQLYEDEVRELEEALRRGQESRLQAEEETRLCAQEAEALRREALGLEQLRARLEDALLRMREEYGIQAEERQRVIDCLEDEKATLTLAMADWLRDYQDLLQVKTGLSLEVATYRALLEGESNPEIVIWAEHVENMPSEFRNKSYHYTDSLLQRENERNLFSRQKAPLASFNHSSALYSNLSGHRGSQTGTSIGGDARRGFLGSGYSSSATTQQENSYGKAVSSQTNVRTFSPTYGLLRNTEAQVKTFPDRPKAGDTREVPVYIGEDSTIARESYRDRRDKVAAGASESTRSNERTVILGKKTEVKATREQERNRPETIRTKPEEKMFDSKEKASEERNLRWEELTKLDKEARQRESQQMKEKAKEKDSPKEKSVREREVPISLEVSQDRRAEVSPKGLQTPVKDAGGGTGREAEARELRFRLGTSDATGSLQGDSMTETVAENIVTSILKQFTQSPETEASADSFPDTKVTYVDRKELPGERKTKTEIVVESKLTEDVDVSDEAGLDYLLSKDIKEVGLKGKSAEQMIGDIINLGLKGREGRAKVVNVEIVEEPVSYVSGEKPEEFSVPFKVEEVEDVSPGPWGLVKEEEGYGESDVTFSVNQHRRTKQPQENTTHVEEVTEAGDSEGEQSYFVSTPDEHPGGHDRDDGSVYGQIHIEEESTIRYSWQDEIVQGTRRRTQKDGAVGEKVVKPLDVPAPSLEGDLGSTHWKEQARSGEFHAEPTVIEKEIKIPHEFHTSMKGISSKEPRQQLVEVIGQLEETLPERMREELSALTREGQGGPGSVSVDVKKVQGAGGSSVTLVAEVNVSQTVDADRLDLEELSKDEASEMEKAVESVVRESLSRQRSPAPGSPDEEGGAEAPAAGIRFRRWATRELYIPSGESEVAGGASHSSGQRTPQGPVSATVEVSSPTGFAQSQVLEDVSQAARHIKLGPSEVWRTERMSYEGPTAEVVEMDVSNVEAIRSRTQEAGALGVSDRGSWRDADSRNDQAVGVSFKASAGEGDQAHREQGKEQAMFDKKVQLQRMVDQRSVISDEKKVALLYLDNEEEENDGHWF

Target ORF information:

RefSeq Version	NM_015286.6
Organism	Homo sapiens(human)
Definition	Homo sapiens synemin (SYNM), transcript variant B, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015286.6

ORF Insert Sequence:

ATGCTGTCCT GGCGGCTGCA GACGGGCCCC GAGAAGGCCG AGCTCCAGGA GCTCAACGCC 
CGGCTCTATG ACTACGTGTG TCGGGTGCGG GAGCTGGAGC GCGAAAACCT ACTCCTGGAG 
GAGGAGCTGC GCGGCCGGCG CGGGCGAGAG GGCCTGTGGG CCGAGGGGCA GGCCCGCTGC 
GCCGAGGAGG CGCGCAGCTT GCGGCAGCAG CTGGACGAGC TGAGCTGGGC CACTGCGCTG 
GCGGAGGGCG AGCGGGACGC TCTGCGGCGC GAGCTGCGGG AGCTGCAGCG CCTGGATGCG 
GAGGAGCGCG CCGCCCGCGG CCGCCTGGAC GCCGAGCTGG GTGCGCAGCA GCGCGAGCTG 
CAGGAGGCGC TGGGCGCGCG CGCCGCCCTC GAGGCGCTGC TGGGCCGGCT GCAGGCCGAG 
CGCCGAGGCC TCGACGCGGC CCACGAACGC GACGTGAGGG AGCTGCGCGC GCGCGCCGCC 
AGCCTTACCA TGCATTTCCG CGCCCGCGCC ACCGGCCCCG CCGCGCCGCC GCCACGCCTG 
CGGGAGGTGC ACGACAGCTA CGCACTGCTG GTGGCCGAGT CGTGGCGGGA GACGGTGCAG 
CTGTACGAGG ACGAGGTGCG CGAGCTGGAG GAGGCGCTGC GGCGCGGCCA GGAGAGCAGA 
CTCCAGGCGG AGGAAGAGAC GCGGCTGTGC GCGCAGGAGG CAGAGGCGCT GCGGCGCGAG 
GCGCTCGGGT TGGAGCAGCT GCGCGCGCGG CTGGAGGACG CGCTGCTGCG GATGCGCGAG 
GAGTACGGGA TACAGGCCGA GGAGCGGCAG AGAGTGATTG ACTGCCTGGA GGATGAGAAG 
GCAACCCTCA CCTTGGCCAT GGCTGACTGG CTGCGGGACT ATCAGGACCT CCTGCAGGTG 
AAGACCGGCC TCAGTCTGGA GGTGGCGACC TACCGGGCCT TATTGGAAGG AGAAAGTAAT 
CCAGAGATAG TGATCTGGGC TGAGCACGTT GAAAACATGC CGTCAGAATT CAGAAACAAA 
TCCTATCACT ATACCGACTC ACTACTACAG AGGGAAAATG AAAGGAATCT ATTTTCAAGG 
CAGAAAGCAC CTTTGGCAAG TTTCAATCAC AGCTCGGCAC TGTATTCTAA CCTGTCAGGG 
CACCGTGGAT CTCAGACGGG CACATCTATT GGAGGTGATG CCAGAAGAGG CTTCTTGGGC 
TCGGGATATT CTTCCTCGGC CACTACCCAG CAGGAAAACT CATACGGAAA AGCCGTCAGC 
AGTCAAACCA ACGTCAGAAC TTTCTCTCCA ACCTATGGCC TTTTAAGAAA TACTGAGGCT 
CAAGTGAAAA CATTCCCTGA CAGACCAAAA GCCGGAGATA CAAGGGAGGT CCCCGTTTAC 
ATAGGTGAAG ATTCCACAAT TGCCCGCGAG TCGTACCGGG ATCGCCGAGA CAAGGTGGCA 
GCAGGTGCTT CGGAAAGCAC ACGGTCAAAT GAGAGGACCG TCATTCTGGG AAAGAAAACA 
GAAGTGAAAG CCACGAGGGA GCAAGAAAGA AACAGACCAG AAACCATCCG AACAAAGCCA 
GAAGAGAAAA TGTTCGATTC TAAAGAGAAG GCTTCCGAGG AGAGAAACCT AAGATGGGAA 
GAATTGACAA AGTTAGATAA GGAAGCGAGA CAGAGAGAAA GCCAGCAGAT GAAGGAGAAG 
GCTAAGGAGA AGGACTCACC GAAGGAGAAG AGCGTGCGAG AGAGAGAGGT GCCGATTAGT 
CTAGAAGTAT CCCAGGACAG AAGAGCAGAG GTGTCCCCGA AAGGTTTGCA GACGCCTGTG 
AAGGATGCTG GTGGTGGGAC CGGTAGAGAG GCAGAAGCAA GAGAGCTACG GTTCAGGTTG 
GGCACCAGTG ATGCCACTGG TTCTCTGCAA GGCGATTCCA TGACAGAAAC CGTAGCAGAA 
AACATCGTTA CCAGTATCCT GAAGCAGTTC ACTCAGTCTC CAGAGACAGA AGCATCTGCT 
GATTCTTTTC CAGACACAAA AGTCACTTAC GTGGACAGGA AAGAGCTTCC TGGGGAAAGG 
AAAACAAAGA CTGAAATAGT TGTGGAGTCT AAACTGACTG AGGATGTTGA TGTTTCCGAT 
GAAGCTGGCC TGGACTACCT TTTAAGCAAG GATATTAAGG AAGTGGGGCT GAAAGGCAAG 
TCAGCCGAGC AGATGATAGG AGACATCATC AACCTCGGCC TGAAAGGGAG GGAGGGGAGA 
GCAAAGGTCG TCAACGTGGA GATCGTGGAG GAGCCCGTGA GTTATGTCAG CGGGGAGAAG 
CCGGAGGAGT TTTCCGTCCC ATTCAAAGTG GAGGAGGTCG AAGATGTGTC GCCAGGCCCC 
TGGGGGTTGG TTAAGGAGGA GGAAGGTTAT GGAGAAAGCG ATGTCACATT CTCAGTTAAT 
CAGCATCGAA GGACCAAGCA GCCTCAGGAG AACACGACTC ACGTGGAAGA AGTGACAGAG 
GCAGGTGATT CAGAGGGCGA GCAGAGTTAT TTTGTGTCCA CTCCAGATGA ACACCCCGGG 
GGGCACGACA GAGATGACGG CTCGGTGTAC GGGCAGATCC ACATCGAGGA GGAATCCACC 
ATCAGGTACT CTTGGCAGGA TGAAATCGTG CAGGGGACTC GAAGGAGGAC ACAGAAGGAC 
GGTGCAGTGG GCGAGAAGGT TGTGAAGCCC TTGGATGTCC CAGCGCCCTC TCTGGAGGGG 
GACCTGGGTT CCACTCACTG GAAAGAACAA GCTAGAAGCG GTGAATTTCA TGCCGAACCC 
ACAGTCATTG AAAAAGAAAT TAAAATACCC CACGAATTCC ACACCTCCAT GAAGGGCATC 
TCCTCCAAGG AGCCCCGGCA GCAGCTGGTG GAGGTCATCG GGCAGCTGGA GGAAACCCTT 
CCCGAGCGCA TGAGGGAGGA GCTGTCCGCC CTCACCAGAG AGGGGCAGGG TGGGCCGGGG 
AGCGTTTCCG TGGATGTCAA GAAGGTCCAG GGTGCTGGTG GCAGTTCCGT GACCCTGGTT 
GCTGAAGTCA ACGTCTCACA AACTGTGGAT GCCGATCGGT TAGACCTGGA GGAGCTGAGC 
AAAGATGAGG CCAGTGAGAT GGAGAAGGCT GTGGAGTCGG TGGTTCGGGA GAGCCTGAGC 
AGGCAACGCA GCCCAGCGCC TGGCAGCCCA GATGAGGAAG GTGGAGCGGA GGCCCCGGCT 
GCTGGCATTC GCTTTAGGCG TTGGGCCACC CGGGAGCTGT ACATCCCTTC AGGCGAGAGC 
GAGGTTGCTG GTGGGGCCTC TCACAGCTCG GGACAGCGCA CTCCCCAGGG CCCAGTGTCG 
GCCACTGTGG AGGTCAGCAG CCCCACAGGC TTTGCCCAGT CACAGGTGCT GGAGGATGTG 
AGCCAGGCTG CAAGGCACAT AAAACTCGGC CCCTCTGAAG TCTGGAGGAC TGAGCGAATG 
TCATATGAAG GACCCACTGC AGAAGTGGTG GAGATGGATG TGAGTAACGT AGAGGCGATC 
CGCAGCCGGA CACAGGAAGC GGGAGCTCTC GGTGTGTCTG ACCGTGGTTC CTGGAGAGAC 
GCGGACAGTA GGAATGACCA GGCAGTTGGT GTGAGCTTTA AGGCCTCTGC TGGGGAAGGA 
GACCAGGCCC ACAGAGAACA GGGCAAGGAG CAGGCCATGT TTGATAAGAA GGTGCAGCTC 
CAGAGAATGG TAGACCAAAG GTCGGTGATT TCAGATGAAA AGAAAGTTGC CCTCCTCTAT 
CTAGACAATG AGGAGGAGGA GAATGATGGG CATTGGTTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SYNM ( NM_015286.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_056101.5 Homo sapiens synemin (SYNM), transcript variant B, mRNA.

Price & Availability↑

CloneID	OHu08894
Clone ID Related Accession (Same CDS sequence)	NM_015286.6 , NM_015286.5
Accession Version	NM_015286.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	synemin isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB002351.2, AW292788.1 and AC036108.19. On Aug 16, 2006 this sequence version replaced NM_015286.4. Transcript Variant: This variant (B) lacks an internal segment of the coding region, compared to variant A. It maintains the reading frame and encodes a shorter isoform (B), compared to isoform A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ310521.1, SRR1803612.30269.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGTCCT GGCGGCTGCA GACGGGCCCC GAGAAGGCCG AGCTCCAGGA GCTCAACGCC 
CGGCTCTATG ACTACGTGTG TCGGGTGCGG GAGCTGGAGC GCGAAAACCT ACTCCTGGAG 
GAGGAGCTGC GCGGCCGGCG CGGGCGAGAG GGCCTGTGGG CCGAGGGGCA GGCCCGCTGC 
GCCGAGGAGG CGCGCAGCTT GCGGCAGCAG CTGGACGAGC TGAGCTGGGC CACTGCGCTG 
GCGGAGGGCG AGCGGGACGC TCTGCGGCGC GAGCTGCGGG AGCTGCAGCG CCTGGATGCG 
GAGGAGCGCG CCGCCCGCGG CCGCCTGGAC GCCGAGCTGG GTGCGCAGCA GCGCGAGCTG 
CAGGAGGCGC TGGGCGCGCG CGCCGCCCTC GAGGCGCTGC TGGGCCGGCT GCAGGCCGAG 
CGCCGAGGCC TCGACGCGGC CCACGAACGC GACGTGAGGG AGCTGCGCGC GCGCGCCGCC 
AGCCTTACCA TGCATTTCCG CGCCCGCGCC ACCGGCCCCG CCGCGCCGCC GCCACGCCTG 
CGGGAGGTGC ACGACAGCTA CGCACTGCTG GTGGCCGAGT CGTGGCGGGA GACGGTGCAG 
CTGTACGAGG ACGAGGTGCG CGAGCTGGAG GAGGCGCTGC GGCGCGGCCA GGAGAGCAGA 
CTCCAGGCGG AGGAAGAGAC GCGGCTGTGC GCGCAGGAGG CAGAGGCGCT GCGGCGCGAG 
GCGCTCGGGT TGGAGCAGCT GCGCGCGCGG CTGGAGGACG CGCTGCTGCG GATGCGCGAG 
GAGTACGGGA TACAGGCCGA GGAGCGGCAG AGAGTGATTG ACTGCCTGGA GGATGAGAAG 
GCAACCCTCA CCTTGGCCAT GGCTGACTGG CTGCGGGACT ATCAGGACCT CCTGCAGGTG 
AAGACCGGCC TCAGTCTGGA GGTGGCGACC TACCGGGCCT TATTGGAAGG AGAAAGTAAT 
CCAGAGATAG TGATCTGGGC TGAGCACGTT GAAAACATGC CGTCAGAATT CAGAAACAAA 
TCCTATCACT ATACCGACTC ACTACTACAG AGGGAAAATG AAAGGAATCT ATTTTCAAGG 
CAGAAAGCAC CTTTGGCAAG TTTCAATCAC AGCTCGGCAC TGTATTCTAA CCTGTCAGGG 
CACCGTGGAT CTCAGACGGG CACATCTATT GGAGGTGATG CCAGAAGAGG CTTCTTGGGC 
TCGGGATATT CTTCCTCGGC CACTACCCAG CAGGAAAACT CATACGGAAA AGCCGTCAGC 
AGTCAAACCA ACGTCAGAAC TTTCTCTCCA ACCTATGGCC TTTTAAGAAA TACTGAGGCT 
CAAGTGAAAA CATTCCCTGA CAGACCAAAA GCCGGAGATA CAAGGGAGGT CCCCGTTTAC 
ATAGGTGAAG ATTCCACAAT TGCCCGCGAG TCGTACCGGG ATCGCCGAGA CAAGGTGGCA 
GCAGGTGCTT CGGAAAGCAC ACGGTCAAAT GAGAGGACCG TCATTCTGGG AAAGAAAACA 
GAAGTGAAAG CCACGAGGGA GCAAGAAAGA AACAGACCAG AAACCATCCG AACAAAGCCA 
GAAGAGAAAA TGTTCGATTC TAAAGAGAAG GCTTCCGAGG AGAGAAACCT AAGATGGGAA 
GAATTGACAA AGTTAGATAA GGAAGCGAGA CAGAGAGAAA GCCAGCAGAT GAAGGAGAAG 
GCTAAGGAGA AGGACTCACC GAAGGAGAAG AGCGTGCGAG AGAGAGAGGT GCCGATTAGT 
CTAGAAGTAT CCCAGGACAG AAGAGCAGAG GTGTCCCCGA AAGGTTTGCA GACGCCTGTG 
AAGGATGCTG GTGGTGGGAC CGGTAGAGAG GCAGAAGCAA GAGAGCTACG GTTCAGGTTG 
GGCACCAGTG ATGCCACTGG TTCTCTGCAA GGCGATTCCA TGACAGAAAC CGTAGCAGAA 
AACATCGTTA CCAGTATCCT GAAGCAGTTC ACTCAGTCTC CAGAGACAGA AGCATCTGCT 
GATTCTTTTC CAGACACAAA AGTCACTTAC GTGGACAGGA AAGAGCTTCC TGGGGAAAGG 
AAAACAAAGA CTGAAATAGT TGTGGAGTCT AAACTGACTG AGGATGTTGA TGTTTCCGAT 
GAAGCTGGCC TGGACTACCT TTTAAGCAAG GATATTAAGG AAGTGGGGCT GAAAGGCAAG 
TCAGCCGAGC AGATGATAGG AGACATCATC AACCTCGGCC TGAAAGGGAG GGAGGGGAGA 
GCAAAGGTCG TCAACGTGGA GATCGTGGAG GAGCCCGTGA GTTATGTCAG CGGGGAGAAG 
CCGGAGGAGT TTTCCGTCCC ATTCAAAGTG GAGGAGGTCG AAGATGTGTC GCCAGGCCCC 
TGGGGGTTGG TTAAGGAGGA GGAAGGTTAT GGAGAAAGCG ATGTCACATT CTCAGTTAAT 
CAGCATCGAA GGACCAAGCA GCCTCAGGAG AACACGACTC ACGTGGAAGA AGTGACAGAG 
GCAGGTGATT CAGAGGGCGA GCAGAGTTAT TTTGTGTCCA CTCCAGATGA ACACCCCGGG 
GGGCACGACA GAGATGACGG CTCGGTGTAC GGGCAGATCC ACATCGAGGA GGAATCCACC 
ATCAGGTACT CTTGGCAGGA TGAAATCGTG CAGGGGACTC GAAGGAGGAC ACAGAAGGAC 
GGTGCAGTGG GCGAGAAGGT TGTGAAGCCC TTGGATGTCC CAGCGCCCTC TCTGGAGGGG 
GACCTGGGTT CCACTCACTG GAAAGAACAA GCTAGAAGCG GTGAATTTCA TGCCGAACCC 
ACAGTCATTG AAAAAGAAAT TAAAATACCC CACGAATTCC ACACCTCCAT GAAGGGCATC 
TCCTCCAAGG AGCCCCGGCA GCAGCTGGTG GAGGTCATCG GGCAGCTGGA GGAAACCCTT 
CCCGAGCGCA TGAGGGAGGA GCTGTCCGCC CTCACCAGAG AGGGGCAGGG TGGGCCGGGG 
AGCGTTTCCG TGGATGTCAA GAAGGTCCAG GGTGCTGGTG GCAGTTCCGT GACCCTGGTT 
GCTGAAGTCA ACGTCTCACA AACTGTGGAT GCCGATCGGT TAGACCTGGA GGAGCTGAGC 
AAAGATGAGG CCAGTGAGAT GGAGAAGGCT GTGGAGTCGG TGGTTCGGGA GAGCCTGAGC 
AGGCAACGCA GCCCAGCGCC TGGCAGCCCA GATGAGGAAG GTGGAGCGGA GGCCCCGGCT 
GCTGGCATTC GCTTTAGGCG TTGGGCCACC CGGGAGCTGT ACATCCCTTC AGGCGAGAGC 
GAGGTTGCTG GTGGGGCCTC TCACAGCTCG GGACAGCGCA CTCCCCAGGG CCCAGTGTCG 
GCCACTGTGG AGGTCAGCAG CCCCACAGGC TTTGCCCAGT CACAGGTGCT GGAGGATGTG 
AGCCAGGCTG CAAGGCACAT AAAACTCGGC CCCTCTGAAG TCTGGAGGAC TGAGCGAATG 
TCATATGAAG GACCCACTGC AGAAGTGGTG GAGATGGATG TGAGTAACGT AGAGGCGATC 
CGCAGCCGGA CACAGGAAGC GGGAGCTCTC GGTGTGTCTG ACCGTGGTTC CTGGAGAGAC 
GCGGACAGTA GGAATGACCA GGCAGTTGGT GTGAGCTTTA AGGCCTCTGC TGGGGAAGGA 
GACCAGGCCC ACAGAGAACA GGGCAAGGAG CAGGCCATGT TTGATAAGAA GGTGCAGCTC 
CAGAGAATGG TAGACCAAAG GTCGGTGATT TCAGATGAAA AGAAAGTTGC CCTCCTCTAT 
CTAGACAATG AGGAGGAGGA GAATGATGGG CATTGGTTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056101.5
CDS	121..3882
Translation	MLSWRLQTGPEKAELQELNARLYDYVCRVRELERENLLLEEELRGRRGREGLWAEGQARCAEEARSLRQQLDELSWATALAEGERDALRRELRELQRLDAEERAARGRLDAELGAQQRELQEALGARAALEALLGRLQAERRGLDAAHERDVRELRARAASLTMHFRARATGPAAPPPRLREVHDSYALLVAESWRETVQLYEDEVRELEEALRRGQESRLQAEEETRLCAQEAEALRREALGLEQLRARLEDALLRMREEYGIQAEERQRVIDCLEDEKATLTLAMADWLRDYQDLLQVKTGLSLEVATYRALLEGESNPEIVIWAEHVENMPSEFRNKSYHYTDSLLQRENERNLFSRQKAPLASFNHSSALYSNLSGHRGSQTGTSIGGDARRGFLGSGYSSSATTQQENSYGKAVSSQTNVRTFSPTYGLLRNTEAQVKTFPDRPKAGDTREVPVYIGEDSTIARESYRDRRDKVAAGASESTRSNERTVILGKKTEVKATREQERNRPETIRTKPEEKMFDSKEKASEERNLRWEELTKLDKEARQRESQQMKEKAKEKDSPKEKSVREREVPISLEVSQDRRAEVSPKGLQTPVKDAGGGTGREAEARELRFRLGTSDATGSLQGDSMTETVAENIVTSILKQFTQSPETEASADSFPDTKVTYVDRKELPGERKTKTEIVVESKLTEDVDVSDEAGLDYLLSKDIKEVGLKGKSAEQMIGDIINLGLKGREGRAKVVNVEIVEEPVSYVSGEKPEEFSVPFKVEEVEDVSPGPWGLVKEEEGYGESDVTFSVNQHRRTKQPQENTTHVEEVTEAGDSEGEQSYFVSTPDEHPGGHDRDDGSVYGQIHIEEESTIRYSWQDEIVQGTRRRTQKDGAVGEKVVKPLDVPAPSLEGDLGSTHWKEQARSGEFHAEPTVIEKEIKIPHEFHTSMKGISSKEPRQQLVEVIGQLEETLPERMREELSALTREGQGGPGSVSVDVKKVQGAGGSSVTLVAEVNVSQTVDADRLDLEELSKDEASEMEKAVESVVRESLSRQRSPAPGSPDEEGGAEAPAAGIRFRRWATRELYIPSGESEVAGGASHSSGQRTPQGPVSATVEVSSPTGFAQSQVLEDVSQAARHIKLGPSEVWRTERMSYEGPTAEVVEMDVSNVEAIRSRTQEAGALGVSDRGSWRDADSRNDQAVGVSFKASAGEGDQAHREQGKEQAMFDKKVQLQRMVDQRSVISDEKKVALLYLDNEEEENDGHWF

Target ORF information:

RefSeq Version	NM_015286.5
Organism	Homo sapiens(human)
Definition	Homo sapiens synemin (SYNM), transcript variant B, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015286.5

ORF Insert Sequence:

ATGCTGTCCT GGCGGCTGCA GACGGGCCCC GAGAAGGCCG AGCTCCAGGA GCTCAACGCC 
CGGCTCTATG ACTACGTGTG TCGGGTGCGG GAGCTGGAGC GCGAAAACCT ACTCCTGGAG 
GAGGAGCTGC GCGGCCGGCG CGGGCGAGAG GGCCTGTGGG CCGAGGGGCA GGCCCGCTGC 
GCCGAGGAGG CGCGCAGCTT GCGGCAGCAG CTGGACGAGC TGAGCTGGGC CACTGCGCTG 
GCGGAGGGCG AGCGGGACGC TCTGCGGCGC GAGCTGCGGG AGCTGCAGCG CCTGGATGCG 
GAGGAGCGCG CCGCCCGCGG CCGCCTGGAC GCCGAGCTGG GTGCGCAGCA GCGCGAGCTG 
CAGGAGGCGC TGGGCGCGCG CGCCGCCCTC GAGGCGCTGC TGGGCCGGCT GCAGGCCGAG 
CGCCGAGGCC TCGACGCGGC CCACGAACGC GACGTGAGGG AGCTGCGCGC GCGCGCCGCC 
AGCCTTACCA TGCATTTCCG CGCCCGCGCC ACCGGCCCCG CCGCGCCGCC GCCACGCCTG 
CGGGAGGTGC ACGACAGCTA CGCACTGCTG GTGGCCGAGT CGTGGCGGGA GACGGTGCAG 
CTGTACGAGG ACGAGGTGCG CGAGCTGGAG GAGGCGCTGC GGCGCGGCCA GGAGAGCAGA 
CTCCAGGCGG AGGAAGAGAC GCGGCTGTGC GCGCAGGAGG CAGAGGCGCT GCGGCGCGAG 
GCGCTCGGGT TGGAGCAGCT GCGCGCGCGG CTGGAGGACG CGCTGCTGCG GATGCGCGAG 
GAGTACGGGA TACAGGCCGA GGAGCGGCAG AGAGTGATTG ACTGCCTGGA GGATGAGAAG 
GCAACCCTCA CCTTGGCCAT GGCTGACTGG CTGCGGGACT ATCAGGACCT CCTGCAGGTG 
AAGACCGGCC TCAGTCTGGA GGTGGCGACC TACCGGGCCT TATTGGAAGG AGAAAGTAAT 
CCAGAGATAG TGATCTGGGC TGAGCACGTT GAAAACATGC CGTCAGAATT CAGAAACAAA 
TCCTATCACT ATACCGACTC ACTACTACAG AGGGAAAATG AAAGGAATCT ATTTTCAAGG 
CAGAAAGCAC CTTTGGCAAG TTTCAATCAC AGCTCGGCAC TGTATTCTAA CCTGTCAGGG 
CACCGTGGAT CTCAGACGGG CACATCTATT GGAGGTGATG CCAGAAGAGG CTTCTTGGGC 
TCGGGATATT CTTCCTCGGC CACTACCCAG CAGGAAAACT CATACGGAAA AGCCGTCAGC 
AGTCAAACCA ACGTCAGAAC TTTCTCTCCA ACCTATGGCC TTTTAAGAAA TACTGAGGCT 
CAAGTGAAAA CATTCCCTGA CAGACCAAAA GCCGGAGATA CAAGGGAGGT CCCCGTTTAC 
ATAGGTGAAG ATTCCACAAT TGCCCGCGAG TCGTACCGGG ATCGCCGAGA CAAGGTGGCA 
GCAGGTGCTT CGGAAAGCAC ACGGTCAAAT GAGAGGACCG TCATTCTGGG AAAGAAAACA 
GAAGTGAAAG CCACGAGGGA GCAAGAAAGA AACAGACCAG AAACCATCCG AACAAAGCCA 
GAAGAGAAAA TGTTCGATTC TAAAGAGAAG GCTTCCGAGG AGAGAAACCT AAGATGGGAA 
GAATTGACAA AGTTAGATAA GGAAGCGAGA CAGAGAGAAA GCCAGCAGAT GAAGGAGAAG 
GCTAAGGAGA AGGACTCACC GAAGGAGAAG AGCGTGCGAG AGAGAGAGGT GCCGATTAGT 
CTAGAAGTAT CCCAGGACAG AAGAGCAGAG GTGTCCCCGA AAGGTTTGCA GACGCCTGTG 
AAGGATGCTG GTGGTGGGAC CGGTAGAGAG GCAGAAGCAA GAGAGCTACG GTTCAGGTTG 
GGCACCAGTG ATGCCACTGG TTCTCTGCAA GGCGATTCCA TGACAGAAAC CGTAGCAGAA 
AACATCGTTA CCAGTATCCT GAAGCAGTTC ACTCAGTCTC CAGAGACAGA AGCATCTGCT 
GATTCTTTTC CAGACACAAA AGTCACTTAC GTGGACAGGA AAGAGCTTCC TGGGGAAAGG 
AAAACAAAGA CTGAAATAGT TGTGGAGTCT AAACTGACTG AGGATGTTGA TGTTTCCGAT 
GAAGCTGGCC TGGACTACCT TTTAAGCAAG GATATTAAGG AAGTGGGGCT GAAAGGCAAG 
TCAGCCGAGC AGATGATAGG AGACATCATC AACCTCGGCC TGAAAGGGAG GGAGGGGAGA 
GCAAAGGTCG TCAACGTGGA GATCGTGGAG GAGCCCGTGA GTTATGTCAG CGGGGAGAAG 
CCGGAGGAGT TTTCCGTCCC ATTCAAAGTG GAGGAGGTCG AAGATGTGTC GCCAGGCCCC 
TGGGGGTTGG TTAAGGAGGA GGAAGGTTAT GGAGAAAGCG ATGTCACATT CTCAGTTAAT 
CAGCATCGAA GGACCAAGCA GCCTCAGGAG AACACGACTC ACGTGGAAGA AGTGACAGAG 
GCAGGTGATT CAGAGGGCGA GCAGAGTTAT TTTGTGTCCA CTCCAGATGA ACACCCCGGG 
GGGCACGACA GAGATGACGG CTCGGTGTAC GGGCAGATCC ACATCGAGGA GGAATCCACC 
ATCAGGTACT CTTGGCAGGA TGAAATCGTG CAGGGGACTC GAAGGAGGAC ACAGAAGGAC 
GGTGCAGTGG GCGAGAAGGT TGTGAAGCCC TTGGATGTCC CAGCGCCCTC TCTGGAGGGG 
GACCTGGGTT CCACTCACTG GAAAGAACAA GCTAGAAGCG GTGAATTTCA TGCCGAACCC 
ACAGTCATTG AAAAAGAAAT TAAAATACCC CACGAATTCC ACACCTCCAT GAAGGGCATC 
TCCTCCAAGG AGCCCCGGCA GCAGCTGGTG GAGGTCATCG GGCAGCTGGA GGAAACCCTT 
CCCGAGCGCA TGAGGGAGGA GCTGTCCGCC CTCACCAGAG AGGGGCAGGG TGGGCCGGGG 
AGCGTTTCCG TGGATGTCAA GAAGGTCCAG GGTGCTGGTG GCAGTTCCGT GACCCTGGTT 
GCTGAAGTCA ACGTCTCACA AACTGTGGAT GCCGATCGGT TAGACCTGGA GGAGCTGAGC 
AAAGATGAGG CCAGTGAGAT GGAGAAGGCT GTGGAGTCGG TGGTTCGGGA GAGCCTGAGC 
AGGCAACGCA GCCCAGCGCC TGGCAGCCCA GATGAGGAAG GTGGAGCGGA GGCCCCGGCT 
GCTGGCATTC GCTTTAGGCG TTGGGCCACC CGGGAGCTGT ACATCCCTTC AGGCGAGAGC 
GAGGTTGCTG GTGGGGCCTC TCACAGCTCG GGACAGCGCA CTCCCCAGGG CCCAGTGTCG 
GCCACTGTGG AGGTCAGCAG CCCCACAGGC TTTGCCCAGT CACAGGTGCT GGAGGATGTG 
AGCCAGGCTG CAAGGCACAT AAAACTCGGC CCCTCTGAAG TCTGGAGGAC TGAGCGAATG 
TCATATGAAG GACCCACTGC AGAAGTGGTG GAGATGGATG TGAGTAACGT AGAGGCGATC 
CGCAGCCGGA CACAGGAAGC GGGAGCTCTC GGTGTGTCTG ACCGTGGTTC CTGGAGAGAC 
GCGGACAGTA GGAATGACCA GGCAGTTGGT GTGAGCTTTA AGGCCTCTGC TGGGGAAGGA 
GACCAGGCCC ACAGAGAACA GGGCAAGGAG CAGGCCATGT TTGATAAGAA GGTGCAGCTC 
CAGAGAATGG TAGACCAAAG GTCGGTGATT TCAGATGAAA AGAAAGTTGC CCTCCTCTAT 
CTAGACAATG AGGAGGAGGA GAATGATGGG CATTGGTTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SYNM ( NM_145728.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_663780.2 Homo sapiens synemin (SYNM), transcript variant A, mRNA.

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CloneID	OHu18579
Clone ID Related Accession (Same CDS sequence)	NM_145728.2 , NM_145728.3
Accession Version	NM_145728.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4698bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	synemin isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB002351.2, AW292788.1 and AC036108.19. This sequence is a reference standard in the RefSeqGene project. On Aug 16, 2006 this sequence version replaced NM_145728.1. Transcript Variant: This variant (A) encodes the longer isoform (A). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ310522.1, BC151243.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGTCCT GGCGGCTGCA GACGGGCCCC GAGAAGGCCG AGCTCCAGGA GCTCAACGCC 
CGGCTCTATG ACTACGTGTG TCGGGTGCGG GAGCTGGAGC GCGAAAACCT ACTCCTGGAG 
GAGGAGCTGC GCGGCCGGCG CGGGCGAGAG GGCCTGTGGG CCGAGGGGCA GGCCCGCTGC 
GCCGAGGAGG CGCGCAGCTT GCGGCAGCAG CTGGACGAGC TGAGCTGGGC CACTGCGCTG 
GCGGAGGGCG AGCGGGACGC TCTGCGGCGC GAGCTGCGGG AGCTGCAGCG CCTGGATGCG 
GAGGAGCGCG CCGCCCGCGG CCGCCTGGAC GCCGAGCTGG GTGCGCAGCA GCGCGAGCTG 
CAGGAGGCGC TGGGCGCGCG CGCCGCCCTC GAGGCGCTGC TGGGCCGGCT GCAGGCCGAG 
CGCCGAGGCC TCGACGCGGC CCACGAACGC GACGTGAGGG AGCTGCGCGC GCGCGCCGCC 
AGCCTTACCA TGCATTTCCG CGCCCGCGCC ACCGGCCCCG CCGCGCCGCC GCCACGCCTG 
CGGGAGGTGC ACGACAGCTA CGCACTGCTG GTGGCCGAGT CGTGGCGGGA GACGGTGCAG 
CTGTACGAGG ACGAGGTGCG CGAGCTGGAG GAGGCGCTGC GGCGCGGCCA GGAGAGCAGA 
CTCCAGGCGG AGGAAGAGAC GCGGCTGTGC GCGCAGGAGG CAGAGGCGCT GCGGCGCGAG 
GCGCTCGGGT TGGAGCAGCT GCGCGCGCGG CTGGAGGACG CGCTGCTGCG GATGCGCGAG 
GAGTACGGGA TACAGGCCGA GGAGCGGCAG AGAGTGATTG ACTGCCTGGA GGATGAGAAG 
GCAACCCTCA CCTTGGCCAT GGCTGACTGG CTGCGGGACT ATCAGGACCT CCTGCAGGTG 
AAGACCGGCC TCAGTCTGGA GGTGGCGACC TACCGGGCCT TATTGGAAGG AGAAAGTAAT 
CCAGAGATAG TGATCTGGGC TGAGCACGTT GAAAACATGC CGTCAGAATT CAGAAACAAA 
TCCTATCACT ATACCGACTC ACTACTACAG AGGGAAAATG AAAGGAATCT ATTTTCAAGG 
CAGAAAGCAC CTTTGGCAAG TTTCAATCAC AGCTCGGCAC TGTATTCTAA CCTGTCAGGG 
CACCGTGGAT CTCAGACGGG CACATCTATT GGAGGTGATG CCAGAAGAGG CTTCTTGGGC 
TCGGGATATT CTTCCTCGGC CACTACCCAG CAGGAAAACT CATACGGAAA AGCCGTCAGC 
AGTCAAACCA ACGTCAGAAC TTTCTCTCCA ACCTATGGCC TTTTAAGAAA TACTGAGGCT 
CAAGTGAAAA CATTCCCTGA CAGACCAAAA GCCGGAGATA CAAGGGAGGT CCCCGTTTAC 
ATAGGTGAAG ATTCCACAAT TGCCCGCGAG TCGTACCGGG ATCGCCGAGA CAAGGTGGCA 
GCAGGTGCTT CGGAAAGCAC ACGGTCAAAT GAGAGGACCG TCATTCTGGG AAAGAAAACA 
GAAGTGAAAG CCACGAGGGA GCAAGAAAGA AACAGACCAG AAACCATCCG AACAAAGCCA 
GAAGAGAAAA TGTTCGATTC TAAAGAGAAG GCTTCCGAGG AGAGAAACCT AAGATGGGAA 
GAATTGACAA AGTTAGATAA GGAAGCGAGA CAGAGAGAAA GCCAGCAGAT GAAGGAGAAG 
GCTAAGGAGA AGGACTCACC GAAGGAGAAG AGCGTGCGAG AGAGAGAGGT GCCGATTAGT 
CTAGAAGTAT CCCAGGACAG AAGAGCAGAG GTGTCCCCGA AAGGTTTGCA GACGCCTGTG 
AAGGATGCTG GTGGTGGGAC CGGTAGAGAG GCAGAAGCAA GAGAGCTACG GTTCAGGTTG 
GGCACCAGTG ATGCCACTGG TTCTCTGCAA GGCGATTCCA TGACAGAAAC CGTAGCAGAA 
AACATCGTTA CCAGTATCCT GAAGCAGTTC ACTCAGTCTC CAGAGACAGA AGCATCTGCT 
GATTCTTTTC CAGACACAAA AGTCACTTAC GTGGACAGGA AAGAGCTTCC TGGGGAAAGG 
AAAACAAAGA CTGAAATAGT TGTGGAGTCT AAACTGACTG AGGATGTTGA TGTTTCCGAT 
GAAGCTGGCC TGGACTACCT TTTAAGCAAG GATATTAAGG AAGTGGGGCT GAAAGGCAAG 
TCAGCCGAGC AGATGATAGG AGACATCATC AACCTCGGCC TGAAAGGGAG GGAGGGGAGA 
GCAAAGGTCG TCAACGTGGA GATCGTGGAG GAGCCCGTGA GTTATGTCAG CGGGGAGAAG 
CCGGAGGAGT TTTCCGTCCC ATTCAAAGTG GAGGAGGTCG AAGATGTGTC GCCAGGCCCC 
TGGGGGTTGG TTAAGGAGGA GGAAGGTTAT GGAGAAAGCG ATGTCACATT CTCAGTTAAT 
CAGCATCGAA GGACCAAGCA GCCTCAGGAG AACACGACTC ACGTGGAAGA AGTGACAGAG 
GCAGGTGATT CAGAGGGCGA GCAGAGTTAT TTTGTGTCCA CTCCAGATGA ACACCCCGGG 
GGGCACGACA GAGATGACGG CTCGGTGTAC GGGCAGATCC ACATCGAGGA GGAATCCACC 
ATCAGGTACT CTTGGCAGGA TGAAATCGTG CAGGGGACTC GAAGGAGGAC ACAGAAGGAC 
GGTGCAGTGG GCGAGAAGGT TGTGAAGCCC TTGGATGTCC CAGCGCCCTC TCTGGAGGGG 
GACCTGGGTT CCACTCACTG GAAAGAACAA GCTAGAAGCG GTGAATTTCA TGCCGAACCC 
ACAGTCATTG AAAAAGAAAT TAAAATACCC CACGAATTCC ACACCTCCAT GAAGGGCATC 
TCCTCCAAGG AGCCCCGGCA GCAGCTGGTG GAGGTCATCG GGCAGCTGGA GGAAACCCTT 
CCCGAGCGCA TGAGGGAGGA GCTGTCCGCC CTCACCAGAG AGGGGCAGGG TGGGCCGGGG 
AGCGTTTCCG TGGATGTCAA GAAGGTCCAG GGTGCTGGTG GCAGTTCCGT GACCCTGGTT 
GCTGAAGTCA ACGTCTCACA AACTGTGGAT GCCGATCGGT TAGACCTGGA GGAGCTGAGC 
AAAGATGAGG CCAGTGAGAT GGAGAAGGCT GTGGAGTCGG TGGTTCGGGA GAGCCTGAGC 
AGGCAACGCA GCCCAGCGCC TGGCAGCCCA GATGAGGAAG GTGGAGCGGA GGCCCCGGCT 
GCTGGCATTC GCTTTAGGCG TTGGGCCACC CGGGAGCTGT ACATCCCTTC AGGCGAGAGC 
GAGGTTGCTG GTGGGGCCTC TCACAGCTCG GGACAGCGCA CTCCCCAGGG CCCAGTGTCG 
GCCACTGTGG AGGTCAGCAG CCCCACAGGC TTTGCCCAGT CACAGGTGCT GGAGGATGTG 
AGCCAGGCTG CAAGGCACAT AAAACTCGGC CCCTCTGAAG TCTGGAGGAC TGAGCGAATG 
TCATATGAAG GACCCACTGC AGAAGTGGTG GAGGTAAGTG CGGGAGGTGA CCTAAGTCAG 
GCAGCGAGCC CGACCGGAGC CAGCCGGTCT GTGAGGCATG TCACGCTGGG TCCCGGTCAA 
AGTCCACTGT CCAGAGAAGT CATCTTCCTA GGCCCTGCCC CTGCCTGTCC AGAGGCATGG 
GGCTCGCCAG AACCTGGCCC AGCAGAGTCT TCTGCAGATA TGGACGGATC AGGGAGGCAC 
AGCACATTTG GCTGCAGACA ATTTCATGCT GAAAAGGAGA TTATTTTTCA GGGCCCCATT 
TCTGCTGCAG GGAAGGTTGG TGATTATTTT GCAACAGAAG AGTCAGTGGG TACCCAGACT 
TCTGTCAGGC AACTCCAGTT AGGCCCTAAA GAAGGGTTCA GTGGGCAAAT CCAGTTCACA 
GCTCCACTTT CAGACAAGGT GGAGTTGGGT GTCATAGGAG ATTCTGTACA CATGGAAGGG 
TTGCCAGGGA GCAGCACATC CATCAGGCAC ATCAGCATTG GGCCTCAGAG GCATCAGACC 
ACCCAGCAGA TAGTTTACCA TGGGCTGGTT CCCCAACTGG GGGAATCTGG TGACTCAGAG 
AGCACTGTGC ACGGAGAGGG CTCAGCAGAT GTGCACCAGG CCACTCACAG TCATACCTCG 
GGTAGACAAA CCGTTATGAC TGAAAAGAGC ACCTTCCAAA GTGTCGTTTC TGAATCTCCC 
CAGGAGGATA GTGCAGAGGA CACATCAGGG GCAGAAATGA CATCGGGTGT TAGCAGATCC 
TTTAGGCACA TTCGACTAGG TCCTACAGAA ACGGAAACCT CTGAACACAT TGCCATCCGT 
GGACCCGTGT CCAGAACATT TGTGCTTGCT GGTTCAGCGG ACTCCCCTGA GCTAGGCAAG 
TTAGCAGACA GCAGCAGAAC GCTAAGGCAC ATTGCACCAG GGCCCAAAGA AACTTCGTTT 
ACCTTTCAGA TGGATGTGAG TAACGTAGAG GCGATCCGCA GCCGGACACA GGAAGCGGGA 
GCTCTCGGTG TGTCTGACCG TGGTTCCTGG AGAGACGCGG ACAGTAGGAA TGACCAGGCA 
GTTGGTGTGA GCTTTAAGGC CTCTGCTGGG GAAGGAGACC AGGCCCACAG AGAACAGGGC 
AAGGAGCAGG CCATGTTTGA TAAGAAGGTG CAGCTCCAGA GAATGGTAGA CCAAAGGTCG 
GTGATTTCAG ATGAAAAGAA AGTTGCCCTC CTCTATCTAG ACAATGAGGA GGAGGAGAAT 
GATGGGCATT GGTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_663780.2
CDS	121..4818
Translation	MLSWRLQTGPEKAELQELNARLYDYVCRVRELERENLLLEEELRGRRGREGLWAEGQARCAEEARSLRQQLDELSWATALAEGERDALRRELRELQRLDAEERAARGRLDAELGAQQRELQEALGARAALEALLGRLQAERRGLDAAHERDVRELRARAASLTMHFRARATGPAAPPPRLREVHDSYALLVAESWRETVQLYEDEVRELEEALRRGQESRLQAEEETRLCAQEAEALRREALGLEQLRARLEDALLRMREEYGIQAEERQRVIDCLEDEKATLTLAMADWLRDYQDLLQVKTGLSLEVATYRALLEGESNPEIVIWAEHVENMPSEFRNKSYHYTDSLLQRENERNLFSRQKAPLASFNHSSALYSNLSGHRGSQTGTSIGGDARRGFLGSGYSSSATTQQENSYGKAVSSQTNVRTFSPTYGLLRNTEAQVKTFPDRPKAGDTREVPVYIGEDSTIARESYRDRRDKVAAGASESTRSNERTVILGKKTEVKATREQERNRPETIRTKPEEKMFDSKEKASEERNLRWEELTKLDKEARQRESQQMKEKAKEKDSPKEKSVREREVPISLEVSQDRRAEVSPKGLQTPVKDAGGGTGREAEARELRFRLGTSDATGSLQGDSMTETVAENIVTSILKQFTQSPETEASADSFPDTKVTYVDRKELPGERKTKTEIVVESKLTEDVDVSDEAGLDYLLSKDIKEVGLKGKSAEQMIGDIINLGLKGREGRAKVVNVEIVEEPVSYVSGEKPEEFSVPFKVEEVEDVSPGPWGLVKEEEGYGESDVTFSVNQHRRTKQPQENTTHVEEVTEAGDSEGEQSYFVSTPDEHPGGHDRDDGSVYGQIHIEEESTIRYSWQDEIVQGTRRRTQKDGAVGEKVVKPLDVPAPSLEGDLGSTHWKEQARSGEFHAEPTVIEKEIKIPHEFHTSMKGISSKEPRQQLVEVIGQLEETLPERMREELSALTREGQGGPGSVSVDVKKVQGAGGSSVTLVAEVNVSQTVDADRLDLEELSKDEASEMEKAVESVVRESLSRQRSPAPGSPDEEGGAEAPAAGIRFRRWATRELYIPSGESEVAGGASHSSGQRTPQGPVSATVEVSSPTGFAQSQVLEDVSQAARHIKLGPSEVWRTERMSYEGPTAEVVEVSAGGDLSQAASPTGASRSVRHVTLGPGQSPLSREVIFLGPAPACPEAWGSPEPGPAESSADMDGSGRHSTFGCRQFHAEKEIIFQGPISAAGKVGDYFATEESVGTQTSVRQLQLGPKEGFSGQIQFTAPLSDKVELGVIGDSVHMEGLPGSSTSIRHISIGPQRHQTTQQIVYHGLVPQLGESGDSESTVHGEGSADVHQATHSHTSGRQTVMTEKSTFQSVVSESPQEDSAEDTSGAEMTSGVSRSFRHIRLGPTETETSEHIAIRGPVSRTFVLAGSADSPELGKLADSSRTLRHIAPGPKETSFTFQMDVSNVEAIRSRTQEAGALGVSDRGSWRDADSRNDQAVGVSFKASAGEGDQAHREQGKEQAMFDKKVQLQRMVDQRSVISDEKKVALLYLDNEEEENDGHWF

Target ORF information:

RefSeq Version	NM_145728.2
Organism	Homo sapiens(human)
Definition	Homo sapiens synemin (SYNM), transcript variant A, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145728.2

ORF Insert Sequence:

ATGCTGTCCT GGCGGCTGCA GACGGGCCCC GAGAAGGCCG AGCTCCAGGA GCTCAACGCC 
CGGCTCTATG ACTACGTGTG TCGGGTGCGG GAGCTGGAGC GCGAAAACCT ACTCCTGGAG 
GAGGAGCTGC GCGGCCGGCG CGGGCGAGAG GGCCTGTGGG CCGAGGGGCA GGCCCGCTGC 
GCCGAGGAGG CGCGCAGCTT GCGGCAGCAG CTGGACGAGC TGAGCTGGGC CACTGCGCTG 
GCGGAGGGCG AGCGGGACGC TCTGCGGCGC GAGCTGCGGG AGCTGCAGCG CCTGGATGCG 
GAGGAGCGCG CCGCCCGCGG CCGCCTGGAC GCCGAGCTGG GTGCGCAGCA GCGCGAGCTG 
CAGGAGGCGC TGGGCGCGCG CGCCGCCCTC GAGGCGCTGC TGGGCCGGCT GCAGGCCGAG 
CGCCGAGGCC TCGACGCGGC CCACGAACGC GACGTGAGGG AGCTGCGCGC GCGCGCCGCC 
AGCCTTACCA TGCATTTCCG CGCCCGCGCC ACCGGCCCCG CCGCGCCGCC GCCACGCCTG 
CGGGAGGTGC ACGACAGCTA CGCACTGCTG GTGGCCGAGT CGTGGCGGGA GACGGTGCAG 
CTGTACGAGG ACGAGGTGCG CGAGCTGGAG GAGGCGCTGC GGCGCGGCCA GGAGAGCAGA 
CTCCAGGCGG AGGAAGAGAC GCGGCTGTGC GCGCAGGAGG CAGAGGCGCT GCGGCGCGAG 
GCGCTCGGGT TGGAGCAGCT GCGCGCGCGG CTGGAGGACG CGCTGCTGCG GATGCGCGAG 
GAGTACGGGA TACAGGCCGA GGAGCGGCAG AGAGTGATTG ACTGCCTGGA GGATGAGAAG 
GCAACCCTCA CCTTGGCCAT GGCTGACTGG CTGCGGGACT ATCAGGACCT CCTGCAGGTG 
AAGACCGGCC TCAGTCTGGA GGTGGCGACC TACCGGGCCT TATTGGAAGG AGAAAGTAAT 
CCAGAGATAG TGATCTGGGC TGAGCACGTT GAAAACATGC CGTCAGAATT CAGAAACAAA 
TCCTATCACT ATACCGACTC ACTACTACAG AGGGAAAATG AAAGGAATCT ATTTTCAAGG 
CAGAAAGCAC CTTTGGCAAG TTTCAATCAC AGCTCGGCAC TGTATTCTAA CCTGTCAGGG 
CACCGTGGAT CTCAGACGGG CACATCTATT GGAGGTGATG CCAGAAGAGG CTTCTTGGGC 
TCGGGATATT CTTCCTCGGC CACTACCCAG CAGGAAAACT CATACGGAAA AGCCGTCAGC 
AGTCAAACCA ACGTCAGAAC TTTCTCTCCA ACCTATGGCC TTTTAAGAAA TACTGAGGCT 
CAAGTGAAAA CATTCCCTGA CAGACCAAAA GCCGGAGATA CAAGGGAGGT CCCCGTTTAC 
ATAGGTGAAG ATTCCACAAT TGCCCGCGAG TCGTACCGGG ATCGCCGAGA CAAGGTGGCA 
GCAGGTGCTT CGGAAAGCAC ACGGTCAAAT GAGAGGACCG TCATTCTGGG AAAGAAAACA 
GAAGTGAAAG CCACGAGGGA GCAAGAAAGA AACAGACCAG AAACCATCCG AACAAAGCCA 
GAAGAGAAAA TGTTCGATTC TAAAGAGAAG GCTTCCGAGG AGAGAAACCT AAGATGGGAA 
GAATTGACAA AGTTAGATAA GGAAGCGAGA CAGAGAGAAA GCCAGCAGAT GAAGGAGAAG 
GCTAAGGAGA AGGACTCACC GAAGGAGAAG AGCGTGCGAG AGAGAGAGGT GCCGATTAGT 
CTAGAAGTAT CCCAGGACAG AAGAGCAGAG GTGTCCCCGA AAGGTTTGCA GACGCCTGTG 
AAGGATGCTG GTGGTGGGAC CGGTAGAGAG GCAGAAGCAA GAGAGCTACG GTTCAGGTTG 
GGCACCAGTG ATGCCACTGG TTCTCTGCAA GGCGATTCCA TGACAGAAAC CGTAGCAGAA 
AACATCGTTA CCAGTATCCT GAAGCAGTTC ACTCAGTCTC CAGAGACAGA AGCATCTGCT 
GATTCTTTTC CAGACACAAA AGTCACTTAC GTGGACAGGA AAGAGCTTCC TGGGGAAAGG 
AAAACAAAGA CTGAAATAGT TGTGGAGTCT AAACTGACTG AGGATGTTGA TGTTTCCGAT 
GAAGCTGGCC TGGACTACCT TTTAAGCAAG GATATTAAGG AAGTGGGGCT GAAAGGCAAG 
TCAGCCGAGC AGATGATAGG AGACATCATC AACCTCGGCC TGAAAGGGAG GGAGGGGAGA 
GCAAAGGTCG TCAACGTGGA GATCGTGGAG GAGCCCGTGA GTTATGTCAG CGGGGAGAAG 
CCGGAGGAGT TTTCCGTCCC ATTCAAAGTG GAGGAGGTCG AAGATGTGTC GCCAGGCCCC 
TGGGGGTTGG TTAAGGAGGA GGAAGGTTAT GGAGAAAGCG ATGTCACATT CTCAGTTAAT 
CAGCATCGAA GGACCAAGCA GCCTCAGGAG AACACGACTC ACGTGGAAGA AGTGACAGAG 
GCAGGTGATT CAGAGGGCGA GCAGAGTTAT TTTGTGTCCA CTCCAGATGA ACACCCCGGG 
GGGCACGACA GAGATGACGG CTCGGTGTAC GGGCAGATCC ACATCGAGGA GGAATCCACC 
ATCAGGTACT CTTGGCAGGA TGAAATCGTG CAGGGGACTC GAAGGAGGAC ACAGAAGGAC 
GGTGCAGTGG GCGAGAAGGT TGTGAAGCCC TTGGATGTCC CAGCGCCCTC TCTGGAGGGG 
GACCTGGGTT CCACTCACTG GAAAGAACAA GCTAGAAGCG GTGAATTTCA TGCCGAACCC 
ACAGTCATTG AAAAAGAAAT TAAAATACCC CACGAATTCC ACACCTCCAT GAAGGGCATC 
TCCTCCAAGG AGCCCCGGCA GCAGCTGGTG GAGGTCATCG GGCAGCTGGA GGAAACCCTT 
CCCGAGCGCA TGAGGGAGGA GCTGTCCGCC CTCACCAGAG AGGGGCAGGG TGGGCCGGGG 
AGCGTTTCCG TGGATGTCAA GAAGGTCCAG GGTGCTGGTG GCAGTTCCGT GACCCTGGTT 
GCTGAAGTCA ACGTCTCACA AACTGTGGAT GCCGATCGGT TAGACCTGGA GGAGCTGAGC 
AAAGATGAGG CCAGTGAGAT GGAGAAGGCT GTGGAGTCGG TGGTTCGGGA GAGCCTGAGC 
AGGCAACGCA GCCCAGCGCC TGGCAGCCCA GATGAGGAAG GTGGAGCGGA GGCCCCGGCT 
GCTGGCATTC GCTTTAGGCG TTGGGCCACC CGGGAGCTGT ACATCCCTTC AGGCGAGAGC 
GAGGTTGCTG GTGGGGCCTC TCACAGCTCG GGACAGCGCA CTCCCCAGGG CCCAGTGTCG 
GCCACTGTGG AGGTCAGCAG CCCCACAGGC TTTGCCCAGT CACAGGTGCT GGAGGATGTG 
AGCCAGGCTG CAAGGCACAT AAAACTCGGC CCCTCTGAAG TCTGGAGGAC TGAGCGAATG 
TCATATGAAG GACCCACTGC AGAAGTGGTG GAGGTAAGTG CGGGAGGTGA CCTAAGTCAG 
GCAGCGAGCC CGACCGGAGC CAGCCGGTCT GTGAGGCATG TCACGCTGGG TCCCGGTCAA 
AGTCCACTGT CCAGAGAAGT CATCTTCCTA GGCCCTGCCC CTGCCTGTCC AGAGGCATGG 
GGCTCGCCAG AACCTGGCCC AGCAGAGTCT TCTGCAGATA TGGACGGATC AGGGAGGCAC 
AGCACATTTG GCTGCAGACA ATTTCATGCT GAAAAGGAGA TTATTTTTCA GGGCCCCATT 
TCTGCTGCAG GGAAGGTTGG TGATTATTTT GCAACAGAAG AGTCAGTGGG TACCCAGACT 
TCTGTCAGGC AACTCCAGTT AGGCCCTAAA GAAGGGTTCA GTGGGCAAAT CCAGTTCACA 
GCTCCACTTT CAGACAAGGT GGAGTTGGGT GTCATAGGAG ATTCTGTACA CATGGAAGGG 
TTGCCAGGGA GCAGCACATC CATCAGGCAC ATCAGCATTG GGCCTCAGAG GCATCAGACC 
ACCCAGCAGA TAGTTTACCA TGGGCTGGTT CCCCAACTGG GGGAATCTGG TGACTCAGAG 
AGCACTGTGC ACGGAGAGGG CTCAGCAGAT GTGCACCAGG CCACTCACAG TCATACCTCG 
GGTAGACAAA CCGTTATGAC TGAAAAGAGC ACCTTCCAAA GTGTCGTTTC TGAATCTCCC 
CAGGAGGATA GTGCAGAGGA CACATCAGGG GCAGAAATGA CATCGGGTGT TAGCAGATCC 
TTTAGGCACA TTCGACTAGG TCCTACAGAA ACGGAAACCT CTGAACACAT TGCCATCCGT 
GGACCCGTGT CCAGAACATT TGTGCTTGCT GGTTCAGCGG ACTCCCCTGA GCTAGGCAAG 
TTAGCAGACA GCAGCAGAAC GCTAAGGCAC ATTGCACCAG GGCCCAAAGA AACTTCGTTT 
ACCTTTCAGA TGGATGTGAG TAACGTAGAG GCGATCCGCA GCCGGACACA GGAAGCGGGA 
GCTCTCGGTG TGTCTGACCG TGGTTCCTGG AGAGACGCGG ACAGTAGGAA TGACCAGGCA 
GTTGGTGTGA GCTTTAAGGC CTCTGCTGGG GAAGGAGACC AGGCCCACAG AGAACAGGGC 
AAGGAGCAGG CCATGTTTGA TAAGAAGGTG CAGCTCCAGA GAATGGTAGA CCAAAGGTCG 
GTGATTTCAG ATGAAAAGAA AGTTGCCCTC CTCTATCTAG ACAATGAGGA GGAGGAGAAT 
GATGGGCATT GGTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SYNM ( NM_145728.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_663780.2 Homo sapiens synemin (SYNM), transcript variant A, mRNA.

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CloneID	OHu18579
Clone ID Related Accession (Same CDS sequence)	NM_145728.2 , NM_145728.3
Accession Version	NM_145728.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4698bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-18
Organism	Homo sapiens(human)
Product	synemin isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB002351.2, AW292788.1 and AC036108.19. On May 17, 2019 this sequence version replaced NM_145728.2. Transcript Variant: This variant (A) encodes the longer isoform (A). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ310522.1, AB002351.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000336292.11/ ENSP00000336775.7 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGTCCT GGCGGCTGCA GACGGGCCCC GAGAAGGCCG AGCTCCAGGA GCTCAACGCC 
CGGCTCTATG ACTACGTGTG TCGGGTGCGG GAGCTGGAGC GCGAAAACCT ACTCCTGGAG 
GAGGAGCTGC GCGGCCGGCG CGGGCGAGAG GGCCTGTGGG CCGAGGGGCA GGCCCGCTGC 
GCCGAGGAGG CGCGCAGCTT GCGGCAGCAG CTGGACGAGC TGAGCTGGGC CACTGCGCTG 
GCGGAGGGCG AGCGGGACGC TCTGCGGCGC GAGCTGCGGG AGCTGCAGCG CCTGGATGCG 
GAGGAGCGCG CCGCCCGCGG CCGCCTGGAC GCCGAGCTGG GTGCGCAGCA GCGCGAGCTG 
CAGGAGGCGC TGGGCGCGCG CGCCGCCCTC GAGGCGCTGC TGGGCCGGCT GCAGGCCGAG 
CGCCGAGGCC TCGACGCGGC CCACGAACGC GACGTGAGGG AGCTGCGCGC GCGCGCCGCC 
AGCCTTACCA TGCATTTCCG CGCCCGCGCC ACCGGCCCCG CCGCGCCGCC GCCACGCCTG 
CGGGAGGTGC ACGACAGCTA CGCACTGCTG GTGGCCGAGT CGTGGCGGGA GACGGTGCAG 
CTGTACGAGG ACGAGGTGCG CGAGCTGGAG GAGGCGCTGC GGCGCGGCCA GGAGAGCAGA 
CTCCAGGCGG AGGAAGAGAC GCGGCTGTGC GCGCAGGAGG CAGAGGCGCT GCGGCGCGAG 
GCGCTCGGGT TGGAGCAGCT GCGCGCGCGG CTGGAGGACG CGCTGCTGCG GATGCGCGAG 
GAGTACGGGA TACAGGCCGA GGAGCGGCAG AGAGTGATTG ACTGCCTGGA GGATGAGAAG 
GCAACCCTCA CCTTGGCCAT GGCTGACTGG CTGCGGGACT ATCAGGACCT CCTGCAGGTG 
AAGACCGGCC TCAGTCTGGA GGTGGCGACC TACCGGGCCT TATTGGAAGG AGAAAGTAAT 
CCAGAGATAG TGATCTGGGC TGAGCACGTT GAAAACATGC CGTCAGAATT CAGAAACAAA 
TCCTATCACT ATACCGACTC ACTACTACAG AGGGAAAATG AAAGGAATCT ATTTTCAAGG 
CAGAAAGCAC CTTTGGCAAG TTTCAATCAC AGCTCGGCAC TGTATTCTAA CCTGTCAGGG 
CACCGTGGAT CTCAGACGGG CACATCTATT GGAGGTGATG CCAGAAGAGG CTTCTTGGGC 
TCGGGATATT CTTCCTCGGC CACTACCCAG CAGGAAAACT CATACGGAAA AGCCGTCAGC 
AGTCAAACCA ACGTCAGAAC TTTCTCTCCA ACCTATGGCC TTTTAAGAAA TACTGAGGCT 
CAAGTGAAAA CATTCCCTGA CAGACCAAAA GCCGGAGATA CAAGGGAGGT CCCCGTTTAC 
ATAGGTGAAG ATTCCACAAT TGCCCGCGAG TCGTACCGGG ATCGCCGAGA CAAGGTGGCA 
GCAGGTGCTT CGGAAAGCAC ACGGTCAAAT GAGAGGACCG TCATTCTGGG AAAGAAAACA 
GAAGTGAAAG CCACGAGGGA GCAAGAAAGA AACAGACCAG AAACCATCCG AACAAAGCCA 
GAAGAGAAAA TGTTCGATTC TAAAGAGAAG GCTTCCGAGG AGAGAAACCT AAGATGGGAA 
GAATTGACAA AGTTAGATAA GGAAGCGAGA CAGAGAGAAA GCCAGCAGAT GAAGGAGAAG 
GCTAAGGAGA AGGACTCACC GAAGGAGAAG AGCGTGCGAG AGAGAGAGGT GCCGATTAGT 
CTAGAAGTAT CCCAGGACAG AAGAGCAGAG GTGTCCCCGA AAGGTTTGCA GACGCCTGTG 
AAGGATGCTG GTGGTGGGAC CGGTAGAGAG GCAGAAGCAA GAGAGCTACG GTTCAGGTTG 
GGCACCAGTG ATGCCACTGG TTCTCTGCAA GGCGATTCCA TGACAGAAAC CGTAGCAGAA 
AACATCGTTA CCAGTATCCT GAAGCAGTTC ACTCAGTCTC CAGAGACAGA AGCATCTGCT 
GATTCTTTTC CAGACACAAA AGTCACTTAC GTGGACAGGA AAGAGCTTCC TGGGGAAAGG 
AAAACAAAGA CTGAAATAGT TGTGGAGTCT AAACTGACTG AGGATGTTGA TGTTTCCGAT 
GAAGCTGGCC TGGACTACCT TTTAAGCAAG GATATTAAGG AAGTGGGGCT GAAAGGCAAG 
TCAGCCGAGC AGATGATAGG AGACATCATC AACCTCGGCC TGAAAGGGAG GGAGGGGAGA 
GCAAAGGTCG TCAACGTGGA GATCGTGGAG GAGCCCGTGA GTTATGTCAG CGGGGAGAAG 
CCGGAGGAGT TTTCCGTCCC ATTCAAAGTG GAGGAGGTCG AAGATGTGTC GCCAGGCCCC 
TGGGGGTTGG TTAAGGAGGA GGAAGGTTAT GGAGAAAGCG ATGTCACATT CTCAGTTAAT 
CAGCATCGAA GGACCAAGCA GCCTCAGGAG AACACGACTC ACGTGGAAGA AGTGACAGAG 
GCAGGTGATT CAGAGGGCGA GCAGAGTTAT TTTGTGTCCA CTCCAGATGA ACACCCCGGG 
GGGCACGACA GAGATGACGG CTCGGTGTAC GGGCAGATCC ACATCGAGGA GGAATCCACC 
ATCAGGTACT CTTGGCAGGA TGAAATCGTG CAGGGGACTC GAAGGAGGAC ACAGAAGGAC 
GGTGCAGTGG GCGAGAAGGT TGTGAAGCCC TTGGATGTCC CAGCGCCCTC TCTGGAGGGG 
GACCTGGGTT CCACTCACTG GAAAGAACAA GCTAGAAGCG GTGAATTTCA TGCCGAACCC 
ACAGTCATTG AAAAAGAAAT TAAAATACCC CACGAATTCC ACACCTCCAT GAAGGGCATC 
TCCTCCAAGG AGCCCCGGCA GCAGCTGGTG GAGGTCATCG GGCAGCTGGA GGAAACCCTT 
CCCGAGCGCA TGAGGGAGGA GCTGTCCGCC CTCACCAGAG AGGGGCAGGG TGGGCCGGGG 
AGCGTTTCCG TGGATGTCAA GAAGGTCCAG GGTGCTGGTG GCAGTTCCGT GACCCTGGTT 
GCTGAAGTCA ACGTCTCACA AACTGTGGAT GCCGATCGGT TAGACCTGGA GGAGCTGAGC 
AAAGATGAGG CCAGTGAGAT GGAGAAGGCT GTGGAGTCGG TGGTTCGGGA GAGCCTGAGC 
AGGCAACGCA GCCCAGCGCC TGGCAGCCCA GATGAGGAAG GTGGAGCGGA GGCCCCGGCT 
GCTGGCATTC GCTTTAGGCG TTGGGCCACC CGGGAGCTGT ACATCCCTTC AGGCGAGAGC 
GAGGTTGCTG GTGGGGCCTC TCACAGCTCG GGACAGCGCA CTCCCCAGGG CCCAGTGTCG 
GCCACTGTGG AGGTCAGCAG CCCCACAGGC TTTGCCCAGT CACAGGTGCT GGAGGATGTG 
AGCCAGGCTG CAAGGCACAT AAAACTCGGC CCCTCTGAAG TCTGGAGGAC TGAGCGAATG 
TCATATGAAG GACCCACTGC AGAAGTGGTG GAGGTAAGTG CGGGAGGTGA CCTAAGTCAG 
GCAGCGAGCC CGACCGGAGC CAGCCGGTCT GTGAGGCATG TCACGCTGGG TCCCGGTCAA 
AGTCCACTGT CCAGAGAAGT CATCTTCCTA GGCCCTGCCC CTGCCTGTCC AGAGGCATGG 
GGCTCGCCAG AACCTGGCCC AGCAGAGTCT TCTGCAGATA TGGACGGATC AGGGAGGCAC 
AGCACATTTG GCTGCAGACA ATTTCATGCT GAAAAGGAGA TTATTTTTCA GGGCCCCATT 
TCTGCTGCAG GGAAGGTTGG TGATTATTTT GCAACAGAAG AGTCAGTGGG TACCCAGACT 
TCTGTCAGGC AACTCCAGTT AGGCCCTAAA GAAGGGTTCA GTGGGCAAAT CCAGTTCACA 
GCTCCACTTT CAGACAAGGT GGAGTTGGGT GTCATAGGAG ATTCTGTACA CATGGAAGGG 
TTGCCAGGGA GCAGCACATC CATCAGGCAC ATCAGCATTG GGCCTCAGAG GCATCAGACC 
ACCCAGCAGA TAGTTTACCA TGGGCTGGTT CCCCAACTGG GGGAATCTGG TGACTCAGAG 
AGCACTGTGC ACGGAGAGGG CTCAGCAGAT GTGCACCAGG CCACTCACAG TCATACCTCG 
GGTAGACAAA CCGTTATGAC TGAAAAGAGC ACCTTCCAAA GTGTCGTTTC TGAATCTCCC 
CAGGAGGATA GTGCAGAGGA CACATCAGGG GCAGAAATGA CATCGGGTGT TAGCAGATCC 
TTTAGGCACA TTCGACTAGG TCCTACAGAA ACGGAAACCT CTGAACACAT TGCCATCCGT 
GGACCCGTGT CCAGAACATT TGTGCTTGCT GGTTCAGCGG ACTCCCCTGA GCTAGGCAAG 
TTAGCAGACA GCAGCAGAAC GCTAAGGCAC ATTGCACCAG GGCCCAAAGA AACTTCGTTT 
ACCTTTCAGA TGGATGTGAG TAACGTAGAG GCGATCCGCA GCCGGACACA GGAAGCGGGA 
GCTCTCGGTG TGTCTGACCG TGGTTCCTGG AGAGACGCGG ACAGTAGGAA TGACCAGGCA 
GTTGGTGTGA GCTTTAAGGC CTCTGCTGGG GAAGGAGACC AGGCCCACAG AGAACAGGGC 
AAGGAGCAGG CCATGTTTGA TAAGAAGGTG CAGCTCCAGA GAATGGTAGA CCAAAGGTCG 
GTGATTTCAG ATGAAAAGAA AGTTGCCCTC CTCTATCTAG ACAATGAGGA GGAGGAGAAT 
GATGGGCATT GGTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_663780.2
CDS	121..4818
Translation	MLSWRLQTGPEKAELQELNARLYDYVCRVRELERENLLLEEELRGRRGREGLWAEGQARCAEEARSLRQQLDELSWATALAEGERDALRRELRELQRLDAEERAARGRLDAELGAQQRELQEALGARAALEALLGRLQAERRGLDAAHERDVRELRARAASLTMHFRARATGPAAPPPRLREVHDSYALLVAESWRETVQLYEDEVRELEEALRRGQESRLQAEEETRLCAQEAEALRREALGLEQLRARLEDALLRMREEYGIQAEERQRVIDCLEDEKATLTLAMADWLRDYQDLLQVKTGLSLEVATYRALLEGESNPEIVIWAEHVENMPSEFRNKSYHYTDSLLQRENERNLFSRQKAPLASFNHSSALYSNLSGHRGSQTGTSIGGDARRGFLGSGYSSSATTQQENSYGKAVSSQTNVRTFSPTYGLLRNTEAQVKTFPDRPKAGDTREVPVYIGEDSTIARESYRDRRDKVAAGASESTRSNERTVILGKKTEVKATREQERNRPETIRTKPEEKMFDSKEKASEERNLRWEELTKLDKEARQRESQQMKEKAKEKDSPKEKSVREREVPISLEVSQDRRAEVSPKGLQTPVKDAGGGTGREAEARELRFRLGTSDATGSLQGDSMTETVAENIVTSILKQFTQSPETEASADSFPDTKVTYVDRKELPGERKTKTEIVVESKLTEDVDVSDEAGLDYLLSKDIKEVGLKGKSAEQMIGDIINLGLKGREGRAKVVNVEIVEEPVSYVSGEKPEEFSVPFKVEEVEDVSPGPWGLVKEEEGYGESDVTFSVNQHRRTKQPQENTTHVEEVTEAGDSEGEQSYFVSTPDEHPGGHDRDDGSVYGQIHIEEESTIRYSWQDEIVQGTRRRTQKDGAVGEKVVKPLDVPAPSLEGDLGSTHWKEQARSGEFHAEPTVIEKEIKIPHEFHTSMKGISSKEPRQQLVEVIGQLEETLPERMREELSALTREGQGGPGSVSVDVKKVQGAGGSSVTLVAEVNVSQTVDADRLDLEELSKDEASEMEKAVESVVRESLSRQRSPAPGSPDEEGGAEAPAAGIRFRRWATRELYIPSGESEVAGGASHSSGQRTPQGPVSATVEVSSPTGFAQSQVLEDVSQAARHIKLGPSEVWRTERMSYEGPTAEVVEVSAGGDLSQAASPTGASRSVRHVTLGPGQSPLSREVIFLGPAPACPEAWGSPEPGPAESSADMDGSGRHSTFGCRQFHAEKEIIFQGPISAAGKVGDYFATEESVGTQTSVRQLQLGPKEGFSGQIQFTAPLSDKVELGVIGDSVHMEGLPGSSTSIRHISIGPQRHQTTQQIVYHGLVPQLGESGDSESTVHGEGSADVHQATHSHTSGRQTVMTEKSTFQSVVSESPQEDSAEDTSGAEMTSGVSRSFRHIRLGPTETETSEHIAIRGPVSRTFVLAGSADSPELGKLADSSRTLRHIAPGPKETSFTFQMDVSNVEAIRSRTQEAGALGVSDRGSWRDADSRNDQAVGVSFKASAGEGDQAHREQGKEQAMFDKKVQLQRMVDQRSVISDEKKVALLYLDNEEEENDGHWF

Target ORF information:

RefSeq Version	NM_145728.3
Organism	Homo sapiens(human)
Definition	Homo sapiens synemin (SYNM), transcript variant A, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145728.3

ORF Insert Sequence:

ATGCTGTCCT GGCGGCTGCA GACGGGCCCC GAGAAGGCCG AGCTCCAGGA GCTCAACGCC 
CGGCTCTATG ACTACGTGTG TCGGGTGCGG GAGCTGGAGC GCGAAAACCT ACTCCTGGAG 
GAGGAGCTGC GCGGCCGGCG CGGGCGAGAG GGCCTGTGGG CCGAGGGGCA GGCCCGCTGC 
GCCGAGGAGG CGCGCAGCTT GCGGCAGCAG CTGGACGAGC TGAGCTGGGC CACTGCGCTG 
GCGGAGGGCG AGCGGGACGC TCTGCGGCGC GAGCTGCGGG AGCTGCAGCG CCTGGATGCG 
GAGGAGCGCG CCGCCCGCGG CCGCCTGGAC GCCGAGCTGG GTGCGCAGCA GCGCGAGCTG 
CAGGAGGCGC TGGGCGCGCG CGCCGCCCTC GAGGCGCTGC TGGGCCGGCT GCAGGCCGAG 
CGCCGAGGCC TCGACGCGGC CCACGAACGC GACGTGAGGG AGCTGCGCGC GCGCGCCGCC 
AGCCTTACCA TGCATTTCCG CGCCCGCGCC ACCGGCCCCG CCGCGCCGCC GCCACGCCTG 
CGGGAGGTGC ACGACAGCTA CGCACTGCTG GTGGCCGAGT CGTGGCGGGA GACGGTGCAG 
CTGTACGAGG ACGAGGTGCG CGAGCTGGAG GAGGCGCTGC GGCGCGGCCA GGAGAGCAGA 
CTCCAGGCGG AGGAAGAGAC GCGGCTGTGC GCGCAGGAGG CAGAGGCGCT GCGGCGCGAG 
GCGCTCGGGT TGGAGCAGCT GCGCGCGCGG CTGGAGGACG CGCTGCTGCG GATGCGCGAG 
GAGTACGGGA TACAGGCCGA GGAGCGGCAG AGAGTGATTG ACTGCCTGGA GGATGAGAAG 
GCAACCCTCA CCTTGGCCAT GGCTGACTGG CTGCGGGACT ATCAGGACCT CCTGCAGGTG 
AAGACCGGCC TCAGTCTGGA GGTGGCGACC TACCGGGCCT TATTGGAAGG AGAAAGTAAT 
CCAGAGATAG TGATCTGGGC TGAGCACGTT GAAAACATGC CGTCAGAATT CAGAAACAAA 
TCCTATCACT ATACCGACTC ACTACTACAG AGGGAAAATG AAAGGAATCT ATTTTCAAGG 
CAGAAAGCAC CTTTGGCAAG TTTCAATCAC AGCTCGGCAC TGTATTCTAA CCTGTCAGGG 
CACCGTGGAT CTCAGACGGG CACATCTATT GGAGGTGATG CCAGAAGAGG CTTCTTGGGC 
TCGGGATATT CTTCCTCGGC CACTACCCAG CAGGAAAACT CATACGGAAA AGCCGTCAGC 
AGTCAAACCA ACGTCAGAAC TTTCTCTCCA ACCTATGGCC TTTTAAGAAA TACTGAGGCT 
CAAGTGAAAA CATTCCCTGA CAGACCAAAA GCCGGAGATA CAAGGGAGGT CCCCGTTTAC 
ATAGGTGAAG ATTCCACAAT TGCCCGCGAG TCGTACCGGG ATCGCCGAGA CAAGGTGGCA 
GCAGGTGCTT CGGAAAGCAC ACGGTCAAAT GAGAGGACCG TCATTCTGGG AAAGAAAACA 
GAAGTGAAAG CCACGAGGGA GCAAGAAAGA AACAGACCAG AAACCATCCG AACAAAGCCA 
GAAGAGAAAA TGTTCGATTC TAAAGAGAAG GCTTCCGAGG AGAGAAACCT AAGATGGGAA 
GAATTGACAA AGTTAGATAA GGAAGCGAGA CAGAGAGAAA GCCAGCAGAT GAAGGAGAAG 
GCTAAGGAGA AGGACTCACC GAAGGAGAAG AGCGTGCGAG AGAGAGAGGT GCCGATTAGT 
CTAGAAGTAT CCCAGGACAG AAGAGCAGAG GTGTCCCCGA AAGGTTTGCA GACGCCTGTG 
AAGGATGCTG GTGGTGGGAC CGGTAGAGAG GCAGAAGCAA GAGAGCTACG GTTCAGGTTG 
GGCACCAGTG ATGCCACTGG TTCTCTGCAA GGCGATTCCA TGACAGAAAC CGTAGCAGAA 
AACATCGTTA CCAGTATCCT GAAGCAGTTC ACTCAGTCTC CAGAGACAGA AGCATCTGCT 
GATTCTTTTC CAGACACAAA AGTCACTTAC GTGGACAGGA AAGAGCTTCC TGGGGAAAGG 
AAAACAAAGA CTGAAATAGT TGTGGAGTCT AAACTGACTG AGGATGTTGA TGTTTCCGAT 
GAAGCTGGCC TGGACTACCT TTTAAGCAAG GATATTAAGG AAGTGGGGCT GAAAGGCAAG 
TCAGCCGAGC AGATGATAGG AGACATCATC AACCTCGGCC TGAAAGGGAG GGAGGGGAGA 
GCAAAGGTCG TCAACGTGGA GATCGTGGAG GAGCCCGTGA GTTATGTCAG CGGGGAGAAG 
CCGGAGGAGT TTTCCGTCCC ATTCAAAGTG GAGGAGGTCG AAGATGTGTC GCCAGGCCCC 
TGGGGGTTGG TTAAGGAGGA GGAAGGTTAT GGAGAAAGCG ATGTCACATT CTCAGTTAAT 
CAGCATCGAA GGACCAAGCA GCCTCAGGAG AACACGACTC ACGTGGAAGA AGTGACAGAG 
GCAGGTGATT CAGAGGGCGA GCAGAGTTAT TTTGTGTCCA CTCCAGATGA ACACCCCGGG 
GGGCACGACA GAGATGACGG CTCGGTGTAC GGGCAGATCC ACATCGAGGA GGAATCCACC 
ATCAGGTACT CTTGGCAGGA TGAAATCGTG CAGGGGACTC GAAGGAGGAC ACAGAAGGAC 
GGTGCAGTGG GCGAGAAGGT TGTGAAGCCC TTGGATGTCC CAGCGCCCTC TCTGGAGGGG 
GACCTGGGTT CCACTCACTG GAAAGAACAA GCTAGAAGCG GTGAATTTCA TGCCGAACCC 
ACAGTCATTG AAAAAGAAAT TAAAATACCC CACGAATTCC ACACCTCCAT GAAGGGCATC 
TCCTCCAAGG AGCCCCGGCA GCAGCTGGTG GAGGTCATCG GGCAGCTGGA GGAAACCCTT 
CCCGAGCGCA TGAGGGAGGA GCTGTCCGCC CTCACCAGAG AGGGGCAGGG TGGGCCGGGG 
AGCGTTTCCG TGGATGTCAA GAAGGTCCAG GGTGCTGGTG GCAGTTCCGT GACCCTGGTT 
GCTGAAGTCA ACGTCTCACA AACTGTGGAT GCCGATCGGT TAGACCTGGA GGAGCTGAGC 
AAAGATGAGG CCAGTGAGAT GGAGAAGGCT GTGGAGTCGG TGGTTCGGGA GAGCCTGAGC 
AGGCAACGCA GCCCAGCGCC TGGCAGCCCA GATGAGGAAG GTGGAGCGGA GGCCCCGGCT 
GCTGGCATTC GCTTTAGGCG TTGGGCCACC CGGGAGCTGT ACATCCCTTC AGGCGAGAGC 
GAGGTTGCTG GTGGGGCCTC TCACAGCTCG GGACAGCGCA CTCCCCAGGG CCCAGTGTCG 
GCCACTGTGG AGGTCAGCAG CCCCACAGGC TTTGCCCAGT CACAGGTGCT GGAGGATGTG 
AGCCAGGCTG CAAGGCACAT AAAACTCGGC CCCTCTGAAG TCTGGAGGAC TGAGCGAATG 
TCATATGAAG GACCCACTGC AGAAGTGGTG GAGGTAAGTG CGGGAGGTGA CCTAAGTCAG 
GCAGCGAGCC CGACCGGAGC CAGCCGGTCT GTGAGGCATG TCACGCTGGG TCCCGGTCAA 
AGTCCACTGT CCAGAGAAGT CATCTTCCTA GGCCCTGCCC CTGCCTGTCC AGAGGCATGG 
GGCTCGCCAG AACCTGGCCC AGCAGAGTCT TCTGCAGATA TGGACGGATC AGGGAGGCAC 
AGCACATTTG GCTGCAGACA ATTTCATGCT GAAAAGGAGA TTATTTTTCA GGGCCCCATT 
TCTGCTGCAG GGAAGGTTGG TGATTATTTT GCAACAGAAG AGTCAGTGGG TACCCAGACT 
TCTGTCAGGC AACTCCAGTT AGGCCCTAAA GAAGGGTTCA GTGGGCAAAT CCAGTTCACA 
GCTCCACTTT CAGACAAGGT GGAGTTGGGT GTCATAGGAG ATTCTGTACA CATGGAAGGG 
TTGCCAGGGA GCAGCACATC CATCAGGCAC ATCAGCATTG GGCCTCAGAG GCATCAGACC 
ACCCAGCAGA TAGTTTACCA TGGGCTGGTT CCCCAACTGG GGGAATCTGG TGACTCAGAG 
AGCACTGTGC ACGGAGAGGG CTCAGCAGAT GTGCACCAGG CCACTCACAG TCATACCTCG 
GGTAGACAAA CCGTTATGAC TGAAAAGAGC ACCTTCCAAA GTGTCGTTTC TGAATCTCCC 
CAGGAGGATA GTGCAGAGGA CACATCAGGG GCAGAAATGA CATCGGGTGT TAGCAGATCC 
TTTAGGCACA TTCGACTAGG TCCTACAGAA ACGGAAACCT CTGAACACAT TGCCATCCGT 
GGACCCGTGT CCAGAACATT TGTGCTTGCT GGTTCAGCGG ACTCCCCTGA GCTAGGCAAG 
TTAGCAGACA GCAGCAGAAC GCTAAGGCAC ATTGCACCAG GGCCCAAAGA AACTTCGTTT 
ACCTTTCAGA TGGATGTGAG TAACGTAGAG GCGATCCGCA GCCGGACACA GGAAGCGGGA 
GCTCTCGGTG TGTCTGACCG TGGTTCCTGG AGAGACGCGG ACAGTAGGAA TGACCAGGCA 
GTTGGTGTGA GCTTTAAGGC CTCTGCTGGG GAAGGAGACC AGGCCCACAG AGAACAGGGC 
AAGGAGCAGG CCATGTTTGA TAAGAAGGTG CAGCTCCAGA GAATGGTAGA CCAAAGGTCG 
GTGATTTCAG ATGAAAAGAA AGTTGCCCTC CTCTATCTAG ACAATGAGGA GGAGGAGAAT 
GATGGGCATT GGTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SYNM ( XM_017022035.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016877524.1 Homo sapiens synemin (SYNM), transcript variant X1, mRNA.

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CloneID	OHu85326
Clone ID Related Accession (Same CDS sequence)	XM_017022035.1
Accession Version	XM_017022035.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3603bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	synemin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGTCCT GGCGGCTGCA GACGGGCCCC GAGAAGGCCG AGCTCCAGGA GCTCAACGCC 
CGGCTCTATG ACTACGTGTG TCGGGTGCGG GAGCTGGAGC GCGAAAACCT ACTCCTGGAG 
GAGGAGCTGC GCGGCCGGCG CGGGCGAGAG GGCCTGTGGG CCGAGGGGCA GGCCCGCTGC 
GCCGAGGAGG CGCGCAGCTT GCGGCAGCAG CTGGACGAGC TGAGCTGGGC CACTGCGCTG 
GCGGAGGGCG AGCGGGACGC TCTGCGGCGC GAGCTGCGGG AGCTGCAGCG CCTGGATGCG 
GAGGAGCGCG CCGCCCGCGG CCGCCTGGAC GCCGAGCTGG GTGCGCAGCA GCGCGAGCTG 
CAGGAGGCGC TGGGCGCGCG CGCCGCCCTC GAGGCGCTGC TGGGCCGGCT GCAGGCCGAG 
CGCCGAGGCC TCGACGCGGC CCACGAACGC GACGTGAGGG AGCTGCGCGC GCGCGCCGCC 
AGCCTTACCA TGCATTTCCG CGCCCGCGCC ACCGGCCCCG CCGCGCCGCC GCCACGCCTG 
CGGGAGGTGC ACGACAGCTA CGCACTGCTG GTGGCCGAGT CGTGGCGGGA GACGGTGCAG 
CTGTACGAGG ACGAGGTGCG CGAGCTGGAG GAGGCGCTGC GGCGCGGCCA GGAGAGCAGA 
CTCCAGGCGG AGGAAGAGAC GCGGCTGTGC GCGCAGGAGG CAGAGGCGCT GCGGCGCGAG 
GCGCTCGGGT TGGAGCAGCT GCGCGCGCGG CTGGAGGACG CGCTGCTGCG GATGCGCGAG 
GAGTACGGGA TACAGGCCGA GGAGCGGCAG AGAGTGATTG ACTGCCTGGA GGATGAGAAG 
GCAACCCTCA CCTTGGCCAT GGCTGACTGG CTGCGGGACT ATCAGGACCT CCTGCAGGTG 
AAGACCGGCC TCAGTCTGGA GGTGGCGACC TACCGGGCCT TATTGGAAGG AGAAAGTAAT 
CCAGAGATAG TGATCTGGGC TGAGCACGTT GAAAACATGC CGTCAGAATT CAGAAACAAA 
TCCTATCACT ATACCGACTC ACTACTACAG AGGGAAAATG AAAGGAATCT ATTTTCAAGG 
CAGAAAGCAC CTTTGGCAAG TTTCAATCAC AGCTCGGCAC TGTATTCTAA CCTGTCAGGG 
CACCGTGGAT CTCAGACGGG CACATCTATT GGAGGTGATG CCAGAAGAGG CTTCTTGGGC 
TCGGGATATT CTTCCTCGGC CACTACCCAG CAGGAAAACT CATACGGAAA AGCCGTCAGC 
AGTCAAACCA ACGTCAGAAC TTTCTCTCCA ACCTATGGCC TTTTAAGAAA TACTGAGGCT 
CAAGTGAAAA CATTCCCTGA CAGACCAAAA GCCGGAGATA CAAGGGAGGT CCCCGTTTAC 
ATAGGTGAAG ATTCCACAAT TGCCCGCGAG TCGTACCGGG ATCGCCGAGA CAAGGTGGCA 
GCAGGTGCTT CGGAAAGCAC ACGGTCAAAT GAGAGGACCG TCATTCTGGG AAAGAAAACA 
GAAGTGAAAG CCACGAGGGA GCAAGAAAGA AACAGACCAG AAACCATCCG AACAAAGCCA 
GAAGAGAAAA TGTTCGATTC TAAAGAGAAG GCTTCCGAGG AGAGAAACCT AAGATGGGAA 
GAATTGACAA AGTTAGATAA GGAAGCGAGA CAGAGAGAAA GCCAGCAGAT GAAGGAGAAG 
GCTAAGGAGA AGGACTCACC GAAGGAGAAG AGCGTGCGAG AGAGAGAGGT GCCGATTAGT 
CTAGAAGTAT CCCAGGACAG AAGAGCAGAG GTGTCCCCGA AAGGTTTGCA GACGCCTGTG 
AAGGATGCTG GTGGTGGGAC CGGTAGAGAG GCAGAAGCAA GAGAGCTACG GTTCAGGTTG 
GGCACCAGTG ATGCCACTGG TTCTCTGCAA GGCGATTCCA TGACAGAAAC CGTAGCAGAA 
AACATCGTTA CCAGTATCCT GAAGCAGTTC ACTCAGTCTC CAGAGACAGA AGCATCTGCT 
GATTCTTTTC CAGACACAAA AGTCACTTAC GTGGACAGGA AAGAGCTTCC TGGGGAAAGG 
AAAACAAAGA CTGAAATAGT TGTGGAGTCT AAACTGACTG AGGATGTTGA TGTTTCCGAT 
GAAGCTGGCC TGGACTACCT TTTAAGCAAG GATATTAAGG AAGTGGGGCT GAAAGGCAAG 
TCAGCCGAGC AGATGATAGG AGACATCATC AACCTCGGCC TGAAAGGGAG GGAGGGGAGA 
GCAAAGGTCG TCAACGTGGA GATCGTGGAG GAGCCCGTGA GTTATGTCAG CGGGGAGAAG 
CCGGAGGAGT TTTCCGTCCC ATTCAAAGTG GAGGAGGTCG AAGATGTGTC GCCAGGCCCC 
TGGGGGTTGG TTAAGGAGGA GGAAGGTTAT GGAGAAAGCG ATGTCACATT CTCAGTTAAT 
CAGCATCGAA GGACCAAGCA GCCTCAGGAG AACACGACTC ACGTGGAAGA AGTGACAGAG 
GCAGGTGATT CAGAGGGCGA GCAGAGTTAT TTTGTGTCCA CTCCAGATGA ACACCCCGGG 
GGGCACGACA GAGATGACGG CTCGGTGTAC GGGCAGATCC ACATCGAGGA GGAATCCACC 
ATCAGGTACT CTTGGCAGGA TGAAATCGTG CAGGGGACTC GAAGGAGGAC ACAGAAGGAC 
GGTGCAGTGG GCGAGAAGGT TGTGAAGCCC TTGGATGTCC CAGCGCCCTC TCTGGAGGGG 
GACCTGGGTT CCACTCACTG GAAAGAACAA GCTAGAAGCG GTGAATTTCA TGCCGAACCC 
ACAGTCATTG AAAAAGAAAT TAAAATACCC CACGAATTCC ACACCTCCAT GAAGGGCATC 
TCCTCCAAGG AGCCCCGGCA GCAGCTGGTG GAGGTCATCG GGCAGCTGGA GGAAACCCTT 
CCCGAGCGCA TGAGGGAGGA GCTGTCCGCC CTCACCAGAG AGGGGCAGGG TGGGCCGGGG 
AGCGTTTCCG TGGATGTCAA GAAGGTCCAG GGTGCTGGTG GCAGTTCCGT GACCCTGGTT 
GCTGAAGTCA ACGTCTCACA AACTGTGGAT GCCGATCGGT TAGACCTGGA GGAGCTGAGC 
AAAGATGAGG CCAGTGAGAT GGAGAAGGCT GTGGAGTCGG TGGTTCGGGA GAGCCTGAGC 
AGGCAACGCA GCCCAGCGCC TGGCAGCCCA GATGAGGAAG GTGGAGCGGA GGCCCCGGCT 
GCTGGCATTC GCTTTAGGCG TTGGGCCACC CGGGAGCTGT ACATCCCTTC AGGCGAGAGC 
GAGGTTGCTG GTGGGGCCTC TCACAGCTCG GGACAGCGCA CTCCCCAGGG CCCAGTGTCG 
GCCACTGTGG AGGTCAGCAG CCCCACAGGC TTTGCCCAGT CACAGGTGCT GGAGGATGTG 
AGCCAGGCTG CAAGGCACAT AAAACTCGGC CCCTCTGAAG TCTGGAGGAC TGAGCGAATG 
TCATATGAAG GACCCACTGC AGAAGTGGTG GAGTTCTGGA AGCTGGGAAG TCTCAAGGTG 
CCAACAGTTT CATTTCCTGG TGAGGGCTCT CTTCCGGGCC TGCAGACGGC TGTCTTCTCA 
CTGTGTCCTC ACATGGTGGA GAGAGAGATC ATCTCTCTGG TGTCTCTCCT TATAAAGCAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016877524.1
CDS	132..3734
Translation	MLSWRLQTGPEKAELQELNARLYDYVCRVRELERENLLLEEELRGRRGREGLWAEGQARCAEEARSLRQQLDELSWATALAEGERDALRRELRELQRLDAEERAARGRLDAELGAQQRELQEALGARAALEALLGRLQAERRGLDAAHERDVRELRARAASLTMHFRARATGPAAPPPRLREVHDSYALLVAESWRETVQLYEDEVRELEEALRRGQESRLQAEEETRLCAQEAEALRREALGLEQLRARLEDALLRMREEYGIQAEERQRVIDCLEDEKATLTLAMADWLRDYQDLLQVKTGLSLEVATYRALLEGESNPEIVIWAEHVENMPSEFRNKSYHYTDSLLQRENERNLFSRQKAPLASFNHSSALYSNLSGHRGSQTGTSIGGDARRGFLGSGYSSSATTQQENSYGKAVSSQTNVRTFSPTYGLLRNTEAQVKTFPDRPKAGDTREVPVYIGEDSTIARESYRDRRDKVAAGASESTRSNERTVILGKKTEVKATREQERNRPETIRTKPEEKMFDSKEKASEERNLRWEELTKLDKEARQRESQQMKEKAKEKDSPKEKSVREREVPISLEVSQDRRAEVSPKGLQTPVKDAGGGTGREAEARELRFRLGTSDATGSLQGDSMTETVAENIVTSILKQFTQSPETEASADSFPDTKVTYVDRKELPGERKTKTEIVVESKLTEDVDVSDEAGLDYLLSKDIKEVGLKGKSAEQMIGDIINLGLKGREGRAKVVNVEIVEEPVSYVSGEKPEEFSVPFKVEEVEDVSPGPWGLVKEEEGYGESDVTFSVNQHRRTKQPQENTTHVEEVTEAGDSEGEQSYFVSTPDEHPGGHDRDDGSVYGQIHIEEESTIRYSWQDEIVQGTRRRTQKDGAVGEKVVKPLDVPAPSLEGDLGSTHWKEQARSGEFHAEPTVIEKEIKIPHEFHTSMKGISSKEPRQQLVEVIGQLEETLPERMREELSALTREGQGGPGSVSVDVKKVQGAGGSSVTLVAEVNVSQTVDADRLDLEELSKDEASEMEKAVESVVRESLSRQRSPAPGSPDEEGGAEAPAAGIRFRRWATRELYIPSGESEVAGGASHSSGQRTPQGPVSATVEVSSPTGFAQSQVLEDVSQAARHIKLGPSEVWRTERMSYEGPTAEVVEFWKLGSLKVPTVSFPGEGSLPGLQTAVFSLCPHMVEREIISLVSLLIKH

Target ORF information:

RefSeq Version	XM_017022035.1
Organism	Homo sapiens(human)
Definition	Homo sapiens synemin (SYNM), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017022035.1

ORF Insert Sequence:

ATGCTGTCCT GGCGGCTGCA GACGGGCCCC GAGAAGGCCG AGCTCCAGGA GCTCAACGCC 
CGGCTCTATG ACTACGTGTG TCGGGTGCGG GAGCTGGAGC GCGAAAACCT ACTCCTGGAG 
GAGGAGCTGC GCGGCCGGCG CGGGCGAGAG GGCCTGTGGG CCGAGGGGCA GGCCCGCTGC 
GCCGAGGAGG CGCGCAGCTT GCGGCAGCAG CTGGACGAGC TGAGCTGGGC CACTGCGCTG 
GCGGAGGGCG AGCGGGACGC TCTGCGGCGC GAGCTGCGGG AGCTGCAGCG CCTGGATGCG 
GAGGAGCGCG CCGCCCGCGG CCGCCTGGAC GCCGAGCTGG GTGCGCAGCA GCGCGAGCTG 
CAGGAGGCGC TGGGCGCGCG CGCCGCCCTC GAGGCGCTGC TGGGCCGGCT GCAGGCCGAG 
CGCCGAGGCC TCGACGCGGC CCACGAACGC GACGTGAGGG AGCTGCGCGC GCGCGCCGCC 
AGCCTTACCA TGCATTTCCG CGCCCGCGCC ACCGGCCCCG CCGCGCCGCC GCCACGCCTG 
CGGGAGGTGC ACGACAGCTA CGCACTGCTG GTGGCCGAGT CGTGGCGGGA GACGGTGCAG 
CTGTACGAGG ACGAGGTGCG CGAGCTGGAG GAGGCGCTGC GGCGCGGCCA GGAGAGCAGA 
CTCCAGGCGG AGGAAGAGAC GCGGCTGTGC GCGCAGGAGG CAGAGGCGCT GCGGCGCGAG 
GCGCTCGGGT TGGAGCAGCT GCGCGCGCGG CTGGAGGACG CGCTGCTGCG GATGCGCGAG 
GAGTACGGGA TACAGGCCGA GGAGCGGCAG AGAGTGATTG ACTGCCTGGA GGATGAGAAG 
GCAACCCTCA CCTTGGCCAT GGCTGACTGG CTGCGGGACT ATCAGGACCT CCTGCAGGTG 
AAGACCGGCC TCAGTCTGGA GGTGGCGACC TACCGGGCCT TATTGGAAGG AGAAAGTAAT 
CCAGAGATAG TGATCTGGGC TGAGCACGTT GAAAACATGC CGTCAGAATT CAGAAACAAA 
TCCTATCACT ATACCGACTC ACTACTACAG AGGGAAAATG AAAGGAATCT ATTTTCAAGG 
CAGAAAGCAC CTTTGGCAAG TTTCAATCAC AGCTCGGCAC TGTATTCTAA CCTGTCAGGG 
CACCGTGGAT CTCAGACGGG CACATCTATT GGAGGTGATG CCAGAAGAGG CTTCTTGGGC 
TCGGGATATT CTTCCTCGGC CACTACCCAG CAGGAAAACT CATACGGAAA AGCCGTCAGC 
AGTCAAACCA ACGTCAGAAC TTTCTCTCCA ACCTATGGCC TTTTAAGAAA TACTGAGGCT 
CAAGTGAAAA CATTCCCTGA CAGACCAAAA GCCGGAGATA CAAGGGAGGT CCCCGTTTAC 
ATAGGTGAAG ATTCCACAAT TGCCCGCGAG TCGTACCGGG ATCGCCGAGA CAAGGTGGCA 
GCAGGTGCTT CGGAAAGCAC ACGGTCAAAT GAGAGGACCG TCATTCTGGG AAAGAAAACA 
GAAGTGAAAG CCACGAGGGA GCAAGAAAGA AACAGACCAG AAACCATCCG AACAAAGCCA 
GAAGAGAAAA TGTTCGATTC TAAAGAGAAG GCTTCCGAGG AGAGAAACCT AAGATGGGAA 
GAATTGACAA AGTTAGATAA GGAAGCGAGA CAGAGAGAAA GCCAGCAGAT GAAGGAGAAG 
GCTAAGGAGA AGGACTCACC GAAGGAGAAG AGCGTGCGAG AGAGAGAGGT GCCGATTAGT 
CTAGAAGTAT CCCAGGACAG AAGAGCAGAG GTGTCCCCGA AAGGTTTGCA GACGCCTGTG 
AAGGATGCTG GTGGTGGGAC CGGTAGAGAG GCAGAAGCAA GAGAGCTACG GTTCAGGTTG 
GGCACCAGTG ATGCCACTGG TTCTCTGCAA GGCGATTCCA TGACAGAAAC CGTAGCAGAA 
AACATCGTTA CCAGTATCCT GAAGCAGTTC ACTCAGTCTC CAGAGACAGA AGCATCTGCT 
GATTCTTTTC CAGACACAAA AGTCACTTAC GTGGACAGGA AAGAGCTTCC TGGGGAAAGG 
AAAACAAAGA CTGAAATAGT TGTGGAGTCT AAACTGACTG AGGATGTTGA TGTTTCCGAT 
GAAGCTGGCC TGGACTACCT TTTAAGCAAG GATATTAAGG AAGTGGGGCT GAAAGGCAAG 
TCAGCCGAGC AGATGATAGG AGACATCATC AACCTCGGCC TGAAAGGGAG GGAGGGGAGA 
GCAAAGGTCG TCAACGTGGA GATCGTGGAG GAGCCCGTGA GTTATGTCAG CGGGGAGAAG 
CCGGAGGAGT TTTCCGTCCC ATTCAAAGTG GAGGAGGTCG AAGATGTGTC GCCAGGCCCC 
TGGGGGTTGG TTAAGGAGGA GGAAGGTTAT GGAGAAAGCG ATGTCACATT CTCAGTTAAT 
CAGCATCGAA GGACCAAGCA GCCTCAGGAG AACACGACTC ACGTGGAAGA AGTGACAGAG 
GCAGGTGATT CAGAGGGCGA GCAGAGTTAT TTTGTGTCCA CTCCAGATGA ACACCCCGGG 
GGGCACGACA GAGATGACGG CTCGGTGTAC GGGCAGATCC ACATCGAGGA GGAATCCACC 
ATCAGGTACT CTTGGCAGGA TGAAATCGTG CAGGGGACTC GAAGGAGGAC ACAGAAGGAC 
GGTGCAGTGG GCGAGAAGGT TGTGAAGCCC TTGGATGTCC CAGCGCCCTC TCTGGAGGGG 
GACCTGGGTT CCACTCACTG GAAAGAACAA GCTAGAAGCG GTGAATTTCA TGCCGAACCC 
ACAGTCATTG AAAAAGAAAT TAAAATACCC CACGAATTCC ACACCTCCAT GAAGGGCATC 
TCCTCCAAGG AGCCCCGGCA GCAGCTGGTG GAGGTCATCG GGCAGCTGGA GGAAACCCTT 
CCCGAGCGCA TGAGGGAGGA GCTGTCCGCC CTCACCAGAG AGGGGCAGGG TGGGCCGGGG 
AGCGTTTCCG TGGATGTCAA GAAGGTCCAG GGTGCTGGTG GCAGTTCCGT GACCCTGGTT 
GCTGAAGTCA ACGTCTCACA AACTGTGGAT GCCGATCGGT TAGACCTGGA GGAGCTGAGC 
AAAGATGAGG CCAGTGAGAT GGAGAAGGCT GTGGAGTCGG TGGTTCGGGA GAGCCTGAGC 
AGGCAACGCA GCCCAGCGCC TGGCAGCCCA GATGAGGAAG GTGGAGCGGA GGCCCCGGCT 
GCTGGCATTC GCTTTAGGCG TTGGGCCACC CGGGAGCTGT ACATCCCTTC AGGCGAGAGC 
GAGGTTGCTG GTGGGGCCTC TCACAGCTCG GGACAGCGCA CTCCCCAGGG CCCAGTGTCG 
GCCACTGTGG AGGTCAGCAG CCCCACAGGC TTTGCCCAGT CACAGGTGCT GGAGGATGTG 
AGCCAGGCTG CAAGGCACAT AAAACTCGGC CCCTCTGAAG TCTGGAGGAC TGAGCGAATG 
TCATATGAAG GACCCACTGC AGAAGTGGTG GAGTTCTGGA AGCTGGGAAG TCTCAAGGTG 
CCAACAGTTT CATTTCCTGG TGAGGGCTCT CTTCCGGGCC TGCAGACGGC TGTCTTCTCA 
CTGTGTCCTC ACATGGTGGA GAGAGAGATC ATCTCTCTGG TGTCTCTCCT TATAAAGCAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM.
Arteriosclerosis, thrombosis, and vascular biology36(9)1947-61(2016 Sep)
Perisic Matic L,Rykaczewska U,Razuvaev A,Sabater-Lleal M,Lengquist M,Miller CL,Ericsson I,R?hl S,Kronqvist M,Aldi S,Magn? J,Paloschi V,Vesterlund M,Li Y,Jin H,Diez MG,Roy J,Baldassarre D,Veglia F,Humphries SE,de Faire U,Tremoli E,Odeberg J,Vukojevi? V,Lehti? J,Maegdefessel L,Ehrenborg E,Paulsson-Berne G,Hansson GK,Lindeman JH,Eriksson P,Quertermous T,Hamsten A,Hedin U

?-Synemin localizes to the M-band of the sarcomere through interaction with the M10 region of titin.
FEBS letters588(24)4625-30(2014 Dec)
Prudner BC,Roy PS,Damron DS,Russell MA

Synemin is expressed in reactive astrocytes and Rosenthal fibers in Alexander disease.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica122(1)76-80(2014 Jan)
Pekny T,Faiz M,Wilhelmsson U,Curtis MA,Matej R,Skalli O,Pekny M

Synemin promotes AKT-dependent glioblastoma cell proliferation by antagonizing PP2A.
Molecular biology of the cell23(7)1243-53(2012 Apr)
Pitre A,Davis N,Paul M,Orr AW,Skalli O

Synemin down-regulation in human hepatocellular carcinoma does not destabilize cytoskeletons in vivo.
Biochemical and biophysical research communications404(1)488-93(2011 Jan)
Liu YH,Cheng CC,Lai YS,Chao WT,Pei RJ,Hsu YH,Ho CC

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SYNM cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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