Snrpb cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Snrpb
Entrez Gene ID	20638
Full Name	small nuclear ribonucleoprotein B
Synonyms	AL024368,AU018828,SM-B,SM11,SMB,SNRNP-B
General protein information	Preferred Names small nuclear ribonucleoprotein B Names small nuclear ribonucleoprotein-associated protein B sm protein B
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2 F1\|2 63.19 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006499059.3	XP_006499122.1	small nuclear ribonucleoprotein-associated protein B isoform X1
XM_006499059.4	XP_006499122.1	small nuclear ribonucleoprotein-associated protein B isoform X1
NM_009225.2	NP_033251.1	small nuclear ribonucleoprotein-associated protein B

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SNRPB	XP_861671.1
Homo sapiens (human)	SNRPB	NP_937859.1
Bos taurus (cattle)	SNRPB	NP_001029903.1
Mus musculus (house mouse)	Snrpb	NP_033251.1
Pan troglodytes (chimpanzee)	SNRPB	XP_525398.2
	SNRPB	XP_001113951.1
Rattus norvegicus (Norway rat)	Snrpb	NP_599185.1

Gene Ontology
Bibliography

Related articles in PubMed

Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss.
Scekic-Zahirovic J, Sendscheid O, El Oussini H, Jambeau M, Sun Y, Mersmann S, Wagner M, Dieterl? S, Sinniger J, Dirrig-Grosch S, Drenner K, Birling MC, Qiu J, Zhou Y, Li H, Fu XD, Rouaux C, Shelkovnikova T, Witting A, Ludolph AC, Kiefer F, Storkebaum E, Lagier-Tourenne C, Dupuis L
The EMBO journal35(10)1077-97(2016 05)

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
Developmental cell17(6)836-48(2009 Dec)

Three proteins of the U7-specific Sm ring function as the molecular ruler to determine the site of 3'-end processing in mammalian histone pre-mRNA.
Yang XC, Torres MP, Marzluff WF, Dominski Z
Molecular and cellular biology29(15)4045-56(2009 Aug)

Promiscuous modification of the nuclear poly(A)-binding protein by multiple protein-arginine methyltransferases does not affect the aggregation behavior.
Fronz K, Otto S, K?lbel K, K?hn U, Friedrich H, Schierhorn A, Beck-Sickinger AG, Ostareck-Lederer A, Wahle E
The Journal of biological chemistry283(29)20408-20(2008 Jul)

The activity of the spinal muscular atrophy protein is regulated during development and cellular differentiation.
Gabanella F, Carissimi C, Usiello A, Pellizzoni L
Human molecular genetics14(23)3629-42(2005 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Snrpb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Snrpb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu20835	NM_009225.2 Latest version!	Mus musculus small nuclear ribonucleoprotein B (Snrpb), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OMu30198	XM_006499059.4 Latest version!	Mus musculus small nuclear ribonucleoprotein B (Snrpb), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu30198	XM_006499059.3	Mus musculus small nuclear ribonucleoprotein B (Snrpb), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Snrpb ( NM_009225.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033251.1 Mus musculus small nuclear ribonucleoprotein B (Snrpb), mRNA.

Price & Availability↑

CloneID	OMu20835
Clone ID Related Accession (Same CDS sequence)	NM_009225.2
Accession Version	NM_009225.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 696bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	small nuclear ribonucleoprotein-associated protein B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY280308.1, AK077537.1, BG086527.2 and BY474459.1. On Feb 2, 2007 this sequence version replaced NM_009225.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK146319.1, AK077537.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN01164131 [ECO:0000348] ##Evidence-Data-END##

ATGACGGTGG GCAAGAGCAG CAAGATGCTG CAGCACATTG ACTACAGGAT GAGGTGCATC 
CTGCAGGACG GCCGCATCTT CATCGGGACC TTCAAAGCCT TTGACAAGCA CATGAACTTG 
ATCCTGTGTG ACTGTGATGA GTTCAGGAAG ATCAAGCCAA AGAACTCCAA ACAAGCAGAA 
AGGGAAGAGA AGCGAGTCCT TGGTCTGGTG TTGCTTCGAG GGGAGAACCT GGTCTCCATG 
ACAGTAGAAG GACCTCCTCC CAAAGATACT GGCATTGCCC GAGTGCCACT TGCTGGAGCT 
GCTGGGGGGC CAGGCATCGG CAGGGCTGCT GGCAGAGGAA TCCCGGCTGG TGTTCCTATG 
CCCCAGGCTC CTGCAGGACT TGCTGGGCCA GTCCGAGGTG TTGGAGGGCC ATCCCAACAG 
GTGATGACCC CACAAGGAAG AGGCACTGTT GCAGCTGCTG CCGCTGCAGC CACAGCCAGT 
ATTGCAGGAG CCCCAACTCA GTACCCACCT GGTCGTGGGG GTCCTCCTCC ACCTATGGGC 
CGAGGAGCCC CTCCTCCAGG TATGATGGGC CCACCTCCTG GCATGCGGCC TCCCATGGGT 
CCCCCAATGG GGCTCCCTCC TGGCCGAGGA ACTCCAATGG GCATGCCCCC TCCTGGCATG 
CGGCCTCCTC CTCCAGGCAT GCGAGGTCTG CTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033251.1
CDS	129..824
Translation	MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGLPPGRGTPMGMPPPGMRPPPPGMRGLL

Target ORF information:

RefSeq Version	NM_009225.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus small nuclear ribonucleoprotein B (Snrpb), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009225.2

ORF Insert Sequence:

ATGACGGTGG GCAAGAGCAG CAAGATGCTG CAGCACATTG ACTACAGGAT GAGGTGCATC 
CTGCAGGACG GCCGCATCTT CATCGGGACC TTCAAAGCCT TTGACAAGCA CATGAACTTG 
ATCCTGTGTG ACTGTGATGA GTTCAGGAAG ATCAAGCCAA AGAACTCCAA ACAAGCAGAA 
AGGGAAGAGA AGCGAGTCCT TGGTCTGGTG TTGCTTCGAG GGGAGAACCT GGTCTCCATG 
ACAGTAGAAG GACCTCCTCC CAAAGATACT GGCATTGCCC GAGTGCCACT TGCTGGAGCT 
GCTGGGGGGC CAGGCATCGG CAGGGCTGCT GGCAGAGGAA TCCCGGCTGG TGTTCCTATG 
CCCCAGGCTC CTGCAGGACT TGCTGGGCCA GTCCGAGGTG TTGGAGGGCC ATCCCAACAG 
GTGATGACCC CACAAGGAAG AGGCACTGTT GCAGCTGCTG CCGCTGCAGC CACAGCCAGT 
ATTGCAGGAG CCCCAACTCA GTACCCACCT GGTCGTGGGG GTCCTCCTCC ACCTATGGGC 
CGAGGAGCCC CTCCTCCAGG TATGATGGGC CCACCTCCTG GCATGCGGCC TCCCATGGGT 
CCCCCAATGG GGCTCCCTCC TGGCCGAGGA ACTCCAATGG GCATGCCCCC TCCTGGCATG 
CGGCCTCCTC CTCCAGGCAT GCGAGGTCTG CTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Snrpb ( XM_006499059.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006499122.1 Mus musculus small nuclear ribonucleoprotein B (Snrpb), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu30198
Clone ID Related Accession (Same CDS sequence)	XM_006499059.3 , XM_006499059.4
Accession Version	XM_006499059.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 459bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	small nuclear ribonucleoprotein-associated protein B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006499059.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACAGTAG AAGGACCTCC TCCCAAAGAT ACTGGCATTG CCCGAGTGCC ACTTGCTGGA 
GCTGCTGGGG GGCCAGGCAT CGGCAGGGCT GCTGGCAGAG GAATCCCGGC TGGTGTTCCT 
ATGCCCCAGG CTCCTGCAGG ACTTGCTGGG CCAGTCCGAG GTGTTGGAGG GCCATCCCAA 
CAGGTGATGA CCCCACAAGG AAGAGGCACT GTTGCAGCTG CTGCCGCTGC AGCCACAGCC 
AGTATTGCAG GAGCCCCAAC TCAGTACCCA CCTGGTCGTG GGGGTCCTCC TCCACCTATG 
GGCCGAGGAG CCCCTCCTCC AGGTATGATG GGCCCACCTC CTGGCATGCG GCCTCCCATG 
GGTCCCCCAA TGGGGCTCCC TCCTGGCCGA GGAACTCCAA TGGGCATGCC CCCTCCTGGC 
ATGCGGCCTC CTCCTCCAGG CATGCGAGGT CTGCTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006499122.1
CDS	500..958
Translation	MTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGLPPGRGTPMGMPPPGMRPPPPGMRGLL

Target ORF information:

RefSeq Version	XM_006499059.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus small nuclear ribonucleoprotein B (Snrpb), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006499059.3

ORF Insert Sequence:

ATGACAGTAG AAGGACCTCC TCCCAAAGAT ACTGGCATTG CCCGAGTGCC ACTTGCTGGA 
GCTGCTGGGG GGCCAGGCAT CGGCAGGGCT GCTGGCAGAG GAATCCCGGC TGGTGTTCCT 
ATGCCCCAGG CTCCTGCAGG ACTTGCTGGG CCAGTCCGAG GTGTTGGAGG GCCATCCCAA 
CAGGTGATGA CCCCACAAGG AAGAGGCACT GTTGCAGCTG CTGCCGCTGC AGCCACAGCC 
AGTATTGCAG GAGCCCCAAC TCAGTACCCA CCTGGTCGTG GGGGTCCTCC TCCACCTATG 
GGCCGAGGAG CCCCTCCTCC AGGTATGATG GGCCCACCTC CTGGCATGCG GCCTCCCATG 
GGTCCCCCAA TGGGGCTCCC TCCTGGCCGA GGAACTCCAA TGGGCATGCC CCCTCCTGGC 
ATGCGGCCTC CTCCTCCAGG CATGCGAGGT CTGCTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Snrpb ( XM_006499059.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006499122.1 Mus musculus small nuclear ribonucleoprotein B (Snrpb), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu30198
Clone ID Related Accession (Same CDS sequence)	XM_006499059.3 , XM_006499059.4
Accession Version	XM_006499059.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 459bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	small nuclear ribonucleoprotein-associated protein B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006499059.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACAGTAG AAGGACCTCC TCCCAAAGAT ACTGGCATTG CCCGAGTGCC ACTTGCTGGA 
GCTGCTGGGG GGCCAGGCAT CGGCAGGGCT GCTGGCAGAG GAATCCCGGC TGGTGTTCCT 
ATGCCCCAGG CTCCTGCAGG ACTTGCTGGG CCAGTCCGAG GTGTTGGAGG GCCATCCCAA 
CAGGTGATGA CCCCACAAGG AAGAGGCACT GTTGCAGCTG CTGCCGCTGC AGCCACAGCC 
AGTATTGCAG GAGCCCCAAC TCAGTACCCA CCTGGTCGTG GGGGTCCTCC TCCACCTATG 
GGCCGAGGAG CCCCTCCTCC AGGTATGATG GGCCCACCTC CTGGCATGCG GCCTCCCATG 
GGTCCCCCAA TGGGGCTCCC TCCTGGCCGA GGAACTCCAA TGGGCATGCC CCCTCCTGGC 
ATGCGGCCTC CTCCTCCAGG CATGCGAGGT CTGCTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006499122.1
CDS	508..966
Translation	MTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGLPPGRGTPMGMPPPGMRPPPPGMRGLL

Target ORF information:

RefSeq Version	XM_006499059.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus small nuclear ribonucleoprotein B (Snrpb), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006499059.4

ORF Insert Sequence:

ATGACAGTAG AAGGACCTCC TCCCAAAGAT ACTGGCATTG CCCGAGTGCC ACTTGCTGGA 
GCTGCTGGGG GGCCAGGCAT CGGCAGGGCT GCTGGCAGAG GAATCCCGGC TGGTGTTCCT 
ATGCCCCAGG CTCCTGCAGG ACTTGCTGGG CCAGTCCGAG GTGTTGGAGG GCCATCCCAA 
CAGGTGATGA CCCCACAAGG AAGAGGCACT GTTGCAGCTG CTGCCGCTGC AGCCACAGCC 
AGTATTGCAG GAGCCCCAAC TCAGTACCCA CCTGGTCGTG GGGGTCCTCC TCCACCTATG 
GGCCGAGGAG CCCCTCCTCC AGGTATGATG GGCCCACCTC CTGGCATGCG GCCTCCCATG 
GGTCCCCCAA TGGGGCTCCC TCCTGGCCGA GGAACTCCAA TGGGCATGCC CCCTCCTGGC 
ATGCGGCCTC CTCCTCCAGG CATGCGAGGT CTGCTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss.
The EMBO journal35(10)1077-97(2016 05)
Scekic-Zahirovic J,Sendscheid O,El Oussini H,Jambeau M,Sun Y,Mersmann S,Wagner M,Dieterl? S,Sinniger J,Dirrig-Grosch S,Drenner K,Birling MC,Qiu J,Zhou Y,Li H,Fu XD,Rouaux C,Shelkovnikova T,Witting A,Ludolph AC,Kiefer F,Storkebaum E,Lagier-Tourenne C,Dupuis L

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Developmental cell17(6)836-48(2009 Dec)
Yokoyama S,Ito Y,Ueno-Kudoh H,Shimizu H,Uchibe K,Albini S,Mitsuoka K,Miyaki S,Kiso M,Nagai A,Hikata T,Osada T,Fukuda N,Yamashita S,Harada D,Mezzano V,Kasai M,Puri PL,Hayashizaki Y,Okado H,Hashimoto M,Asahara H

Three proteins of the U7-specific Sm ring function as the molecular ruler to determine the site of 3'-end processing in mammalian histone pre-mRNA.
Molecular and cellular biology29(15)4045-56(2009 Aug)
Yang XC,Torres MP,Marzluff WF,Dominski Z

Promiscuous modification of the nuclear poly(A)-binding protein by multiple protein-arginine methyltransferases does not affect the aggregation behavior.
The Journal of biological chemistry283(29)20408-20(2008 Jul)
Fronz K,Otto S,K?lbel K,K?hn U,Friedrich H,Schierhorn A,Beck-Sickinger AG,Ostareck-Lederer A,Wahle E

The activity of the spinal muscular atrophy protein is regulated during development and cellular differentiation.
Human molecular genetics14(23)3629-42(2005 Dec)
Gabanella F,Carissimi C,Usiello A,Pellizzoni L