MATN2 cDNA ORF clone, Mus musculus(House mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	MATN2
Entrez Gene ID	17181
Full Name	matrilin 2
Synonyms	Crtm2,matrilin-2
General protein information	Preferred Names matrilin 2 Names matrilin-2
Gene Type	protein-coding
Organism	Mus musculus(House mouse)
Genome	Chromosome: 15 Map Location: 15\|15 B3.1

mRNA and Protein(s)

mRNA	Protein	Name
NM_016762.2	NP_058042.2	matrilin-2 isoform 2 precursor
NM_001358780.1	NP_001345709.1	matrilin-2 isoform 1 precursor
XM_006520023.2	XP_006520086.1	matrilin-2 isoform X1

Pathways from BioSystems

Homologies

	MATN2	XP_002805471.1
Homo sapiens (human)	MATN2	NP_002371.3
Bos taurus (cattle)	MATN2	NP_001095998.1
Danio rerio (zebrafish)	matn4	NP_998714.1
Pan troglodytes (chimpanzee)	MATN2	XP_003311906.1
Canis lupus familiaris (dog)	MATN2	XP_548552.4
Mus musculus (house mouse)	Matn2	NP_058042.2
Rattus norvegicus (Norway rat)	Matn2	XP_216941.6
Xenopus tropicalis (tropical clawed frog)	matn2	NP_989238.1

Gene Ontology
Bibliography

Related articles in PubMed

Matrilin-2 regulates proliferation, apoptosis and cell cycle during radiation-induced injury in HPAEpiC cell.
Luo J, Zhang M, Huang H, Wang Y, Yuan X, Ma S, Liu J, Zhou S, Zhang S
Biochemical and biophysical research communications485(3)577-583(2017 04)

Absence of collagen IX accelerates hypertrophic differentiation in the embryonic mouse spine through a disturbance of the Ihh-PTHrP feedback loop.
Kamper M, Paulsson M, Zaucke F
Cell and tissue research367(2)359-367(2017 Feb)

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.
Naba A, Clauser KR, Mani DR, Carr SA, Hynes RO
Scientific reports740495(2017 Jan)

The extracellular matrix protein matrilin-2 induces post-burn inflammatory responses as an endogenous danger signal.
Chi Y, Chai J, Xu C, Luo H, Zhang Q
Inflammation research : official journal of the European Histamine Research Society ... [et al.]64(10)833-9(2015 Oct)

Axonally derived matrilin-2 induces proinflammatory responses that exacerbate autoimmune neuroinflammation.
Jonas A, Thiem S, Kuhlmann T, Wagener R, Aszodi A, Nowell C, Hagemeier K, Laverick L, Perreau V, Jokubaitis V, Emery B, Kilpatrick T, Butzkueven H, Gresle M
The Journal of clinical investigation124(11)5042-56(2014 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that the mRNA and protein levels of matrilin-2 were increased after irradiation treatment in both mouse lung tissue and human pulmonary alveolar epithelial cells (HPAEpiC).
Title: Matrilin-2 regulates proliferation, apoptosis and cell cycle during radiation-induced injury in HPAEpiC cell.

Matrilin-2 induces post-burn inflammatory responses as an endogenous danger signal, partly through a TLR4-mediated mechanism
Title: The extracellular matrix protein matrilin-2 induces post-burn inflammatory responses as an endogenous danger signal.

The absence of matrilin-2 has no effect on hepatic stellate cell activation and regression kinetics, synthetic activity, proliferative capacity, motility, or HSC apoptosis.
Title: Upregulation of matrilin-2 expression in murine hepatic stellate cells during liver injury has no effect on fibrosis formation and resolution.

MATN2 is a deleterious endogenous neuroaxonal injury response signal that activates innate immune cells.
Title: Axonally derived matrilin-2 induces proinflammatory responses that exacerbate autoimmune neuroinflammation.

Matrilin-2 may play an important role in the communication of matrix to matrix and matrix to cells and will be used as a potential biomarker in the early stage of osteoarthritis of articular cartilage.
Title: Matrilin-2 is a widely distributed extracellular matrix protein and a potential biomarker in the early stage of osteoarthritis in articular cartilage.

The following MATN2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MATN2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu20787	NM_016762.2 Latest version!	Mus musculus matrilin 2 (Matn2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OMu50659	NM_001358780.1 Latest version!	Mus musculus matrilin 2 (Matn2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OMu50659	XM_006520023.2 Latest version!	Mus musculus matrilin 2 (Matn2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MATN2 ( NM_016762.2 ) cDNA ORF clone, Mus musculus(House mouse) -> NP_058042.2 Mus musculus matrilin 2 (Matn2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu20787
Clone ID Related Accession (Same CDS sequence)	NM_016762.2
Accession Version	NM_016762.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2814bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Mus musculus(house mouse)
Product	matrilin-2 isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY146293.1, AK138211.1 and AK163818.1. On or before Dec 17, 2010 this sequence version replaced XR_106898.1, XR_106899.1, XR_105671.1, XR_105672.1, NM_016762.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK138211.1, BC092298.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849381 [ECO:0000348] ##Evidence-Data-END##

ATGGAGAAGA TGTTGGTGGG GTGCTTGCTG ATGCTTGGGC AGCTCTTCCT TGTCCTCCCA 
GTTGACGGCA GAGAGCGTCC CCAAGCCAGG TTCCCTTCCA GAGGCCGTCA TGTCCGGATG 
TATCCGCAGA CTGCACTGCT GGAGAGTTCC TGTGAGAATA AGCGGGCAGA TCTGGTGTTC 
ATCATTGACA GCTCCCGAAG TGTCAACACC TATGACTATG CAAAGGTCAA GGAGTTCATT 
CTGGATATCC TGCAGTTCTT GGACATCGGT CCTGATGTTA CCCGAGTAGG TCTGCTCCAA 
TATGGCAGCA CGGTCAAGAA CGAGTTCTCC CTGAAGACCT TTAAGAGGAA GTCTGAGGTG 
GAGAGGGCTG TCAAGAGAAT GAGGCATCTA TCCACTGGCA CCATGACAGG GCTTGCCATC 
CAATATGCCC TCAACATTGC CTTCTCAGAA GCAGAGGGGG CCAGGCCCTT GCGGGAAAAT 
GTGCCACGCA TCATAATGAT TGTGACTGAT GGGAGGCCTC AGGACTCGGT GGCTGAGGTA 
GCTGCCAAGG CCCGGAACAC AGGCATCCTG ATCTTTGCCA TCGGTGTCGG TCAGGTGGAC 
CTGAATACAC TAAAGGCCAT TGGGAGTGAG CCCCACAAGG ACCATGTCTT CCTGGTGGCC 
AATTTCAGCC AGATTGAGTC CTTGACCTCA GTGTTCCAGA ACAAACTGTG CACAGTCCAC 
ATGTGCAGCG TCTTGGAACA CAACTGTGCC CACTTCTGCC TCAACACACC TGGCTCGTAC 
ATCTGCAAGT GCAAGCAAGG GTACATTCTC AGCACGGATC AGAAGACTTG CAGAATCCAG 
GATTTGTGTG CCACAGAGGA CCATGGTTGT GAGCAGCTGT GCGTGAACAT GCTGGGTTCC 
TTTGTCTGCC AGTGCTACAG TGGCTACACC TTGGCCGAGG ACGGGAAGCG ATGTACAGCT 
GTGGACTACT GTGCCTCAGA AAATCATGGA TGTGAACACG AGTGTGTAAA TGCTGAAAGT 
TCCTACCTGT GCCGGTGCCA CGAGGGATTT GCTCTTAACA GCGATAAGAA AACATGCTCA 
AAGATTGACT ATTGTGCCTC TTCAAATCAC GGATGTCAGC ATGAGTGTGT CAATGCCCAG 
ACGTCTGCTC TCTGCCGCTG CCTGAAAGGC TTCATGCTAA ATCCAGACAG GAAAACTTGC 
CGAAGGATCA ACTACTGTGC ACTGAACAAA CCAGGCTGTG AGCATGAGTG TGTGAACACA 
GAGGAGGGTC ACTACTGCCG CTGCCGTCAG GGCTACAATC TGGACCCCAA TGGCAAGACC 
TGCAGCCGGG TGGACCACTG TGCACAGCAG GACCATGGCT GTGAGCAGCT GTGCCTGAAC 
ACAGAGGAGT CCTTTGTCTG CCAGTGCTCA GAAGGCTTCC TTATTAATGA TGACCTCAAG 
ACCTGCTCCA GGGCAGATTA CTGCTTGCTG AGCAACCATG GTTGTGAATA CTCCTGCGTC 
AACACAGACA AATCCTTTGC CTGCCAATGT CCTGAGGGTC ATGTGCTCCG AAGCGATGGG 
AAGACCTGTG CAAAACTGGA CTCTTGTGCT TTGGGGGACC ATGGTTGTGA ACATTCATGT 
GTAAGCAGTG AAGACTCTTT CGTGTGTCAG TGCTTTGAGG GGTACATTCT TCGTGACGAT 
GGGAAGACCT GCAGAAGGAA AGATGTCTGC CAGGATGTTA ACCATGGATG TGAGCACCTT 
TGTGTGAACA GTGGCGAATC ATACGTCTGC AAGTGTCTGG AGGGGTTCAG GCTGGCTGAG 
GATGGGAAGC GCTGCAGGAG GAAGAATGTC TGCAAGTCAA CCCAGCATGG CTGTGAGCAC 
ATGTGTGTGA ACAATGGGAA CTCCTATCTG TGCAGGTGCT CAGAGGGCTT TGTCCTAGCT 
GAGGATGGAA AGCACTGCAA GAGATGCACT GAAGGCCCAA TTGACCTGGT CTTTGTGATT 
GATGGATCCA AGAGCCTTGG AGAAGAGAAC TTTGAGACTG TGAAGCACTT TGTCACTGGA 
ATCATAGATT CCTTGGCAGT TTCCCCCAAA GCTGCTCGTG TGGGGCTGCT GCAGTATTCC 
ACACAGGTCC GAACAGAGTT TACCCTGAGG GGCTTCAGCT CAGCCAAGGA AATGAAGAAA 
GCCGTGACCC ACATGAAATA CATGGGCAAA GGCTCTATGA CTGGGCTGGC CCTGAAACAC 
ATGTTTGAGA GAAGTTTTAC CCAAGTAGAA GGGGCCAGGC CCCCCTCCAC GCAGGTACCC 
AGAGTAGCCA TCGTGTTCAC CGACGGACGG GCTCAGGATG ATGTCTCTGA GTGGGCCAGT 
AAAGCCAAGG CCAATGGTAT CACTATGTAT GCCGTTGGGG TAGGAAAAGC CATTGAGGAA 
GAACTACAGG AGATTGCCTC TGAGCCCATT GACAAGCATC TCTTCTACGC TGAAGATTTC 
AGCACAATGG GCGAAATAAG TGAAAAGCTG AAAGAAGGCA TCTGTGAAGC TCTAGAAGAC 
TCTGGTGGAA GACAGGACTC AGCAGCATGG GACCTGCCAC AGCAGGCCCA CCAGCCAACA 
GTGCAACATA GATTCCTGTT TGAAGAAGAC AATCTTTCAC GGTCTACACA AAAACTTTTC 
CATTCAACCA AATCTTCAGG AAACCCTTTG GAAGAAAGCC AGGACCAATG CAAATGTGAA 
AACCTTATAC TGTTCCAGAA CGTTGCAAAT GAAGAAGTAA GAAAATTAAC CCAGCGCTTA 
GAAGAAATGA CTCAAAGAAT GGAAGCTTTG GAAAATCGCC TAAAATACAG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058042.2
CDS	252..3065
Translation	MEKMLVGCLLMLGQLFLVLPVDGRERPQARFPSRGRHVRMYPQTALLESSCENKRADLVFIIDSSRSVNTYDYAKVKEFILDILQFLDIGPDVTRVGLLQYGSTVKNEFSLKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRIIMIVTDGRPQDSVAEVAAKARNTGILIFAIGVGQVDLNTLKAIGSEPHKDHVFLVANFSQIESLTSVFQNKLCTVHMCSVLEHNCAHFCLNTPGSYICKCKQGYILSTDQKTCRIQDLCATEDHGCEQLCVNMLGSFVCQCYSGYTLAEDGKRCTAVDYCASENHGCEHECVNAESSYLCRCHEGFALNSDKKTCSKIDYCASSNHGCQHECVNAQTSALCRCLKGFMLNPDRKTCRRINYCALNKPGCEHECVNTEEGHYCRCRQGYNLDPNGKTCSRVDHCAQQDHGCEQLCLNTEESFVCQCSEGFLINDDLKTCSRADYCLLSNHGCEYSCVNTDKSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILRDDGKTCRRKDVCQDVNHGCEHLCVNSGESYVCKCLEGFRLAEDGKRCRRKNVCKSTQHGCEHMCVNNGNSYLCRCSEGFVLAEDGKHCKRCTEGPIDLVFVIDGSKSLGEENFETVKHFVTGIIDSLAVSPKAARVGLLQYSTQVRTEFTLRGFSSAKEMKKAVTHMKYMGKGSMTGLALKHMFERSFTQVEGARPPSTQVPRVAIVFTDGRAQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIASEPIDKHLFYAEDFSTMGEISEKLKEGICEALEDSGGRQDSAAWDLPQQAHQPTVQHRFLFEEDNLSRSTQKLFHSTKSSGNPLEESQDQCKCENLILFQNVANEEVRKLTQRLEEMTQRMEALENRLKYR

Target ORF information:

RefSeq Version	NM_016762.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus matrilin 2 (Matn2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016762.2

ORF Insert Sequence:

ATGGAGAAGA TGTTGGTGGG GTGCTTGCTG ATGCTTGGGC AGCTCTTCCT TGTCCTCCCA 
GTTGACGGCA GAGAGCGTCC CCAAGCCAGG TTCCCTTCCA GAGGCCGTCA TGTCCGGATG 
TATCCGCAGA CTGCACTGCT GGAGAGTTCC TGTGAGAATA AGCGGGCAGA TCTGGTGTTC 
ATCATTGACA GCTCCCGAAG TGTCAACACC TATGACTATG CAAAGGTCAA GGAGTTCATT 
CTGGATATCC TGCAGTTCTT GGACATCGGT CCTGATGTTA CCCGAGTAGG TCTGCTCCAA 
TATGGCAGCA CGGTCAAGAA CGAGTTCTCC CTGAAGACCT TTAAGAGGAA GTCTGAGGTG 
GAGAGGGCTG TCAAGAGAAT GAGGCATCTA TCCACTGGCA CCATGACAGG GCTTGCCATC 
CAATATGCCC TCAACATTGC CTTCTCAGAA GCAGAGGGGG CCAGGCCCTT GCGGGAAAAT 
GTGCCACGCA TCATAATGAT TGTGACTGAT GGGAGGCCTC AGGACTCGGT GGCTGAGGTA 
GCTGCCAAGG CCCGGAACAC AGGCATCCTG ATCTTTGCCA TCGGTGTCGG TCAGGTGGAC 
CTGAATACAC TAAAGGCCAT TGGGAGTGAG CCCCACAAGG ACCATGTCTT CCTGGTGGCC 
AATTTCAGCC AGATTGAGTC CTTGACCTCA GTGTTCCAGA ACAAACTGTG CACAGTCCAC 
ATGTGCAGCG TCTTGGAACA CAACTGTGCC CACTTCTGCC TCAACACACC TGGCTCGTAC 
ATCTGCAAGT GCAAGCAAGG GTACATTCTC AGCACGGATC AGAAGACTTG CAGAATCCAG 
GATTTGTGTG CCACAGAGGA CCATGGTTGT GAGCAGCTGT GCGTGAACAT GCTGGGTTCC 
TTTGTCTGCC AGTGCTACAG TGGCTACACC TTGGCCGAGG ACGGGAAGCG ATGTACAGCT 
GTGGACTACT GTGCCTCAGA AAATCATGGA TGTGAACACG AGTGTGTAAA TGCTGAAAGT 
TCCTACCTGT GCCGGTGCCA CGAGGGATTT GCTCTTAACA GCGATAAGAA AACATGCTCA 
AAGATTGACT ATTGTGCCTC TTCAAATCAC GGATGTCAGC ATGAGTGTGT CAATGCCCAG 
ACGTCTGCTC TCTGCCGCTG CCTGAAAGGC TTCATGCTAA ATCCAGACAG GAAAACTTGC 
CGAAGGATCA ACTACTGTGC ACTGAACAAA CCAGGCTGTG AGCATGAGTG TGTGAACACA 
GAGGAGGGTC ACTACTGCCG CTGCCGTCAG GGCTACAATC TGGACCCCAA TGGCAAGACC 
TGCAGCCGGG TGGACCACTG TGCACAGCAG GACCATGGCT GTGAGCAGCT GTGCCTGAAC 
ACAGAGGAGT CCTTTGTCTG CCAGTGCTCA GAAGGCTTCC TTATTAATGA TGACCTCAAG 
ACCTGCTCCA GGGCAGATTA CTGCTTGCTG AGCAACCATG GTTGTGAATA CTCCTGCGTC 
AACACAGACA AATCCTTTGC CTGCCAATGT CCTGAGGGTC ATGTGCTCCG AAGCGATGGG 
AAGACCTGTG CAAAACTGGA CTCTTGTGCT TTGGGGGACC ATGGTTGTGA ACATTCATGT 
GTAAGCAGTG AAGACTCTTT CGTGTGTCAG TGCTTTGAGG GGTACATTCT TCGTGACGAT 
GGGAAGACCT GCAGAAGGAA AGATGTCTGC CAGGATGTTA ACCATGGATG TGAGCACCTT 
TGTGTGAACA GTGGCGAATC ATACGTCTGC AAGTGTCTGG AGGGGTTCAG GCTGGCTGAG 
GATGGGAAGC GCTGCAGGAG GAAGAATGTC TGCAAGTCAA CCCAGCATGG CTGTGAGCAC 
ATGTGTGTGA ACAATGGGAA CTCCTATCTG TGCAGGTGCT CAGAGGGCTT TGTCCTAGCT 
GAGGATGGAA AGCACTGCAA GAGATGCACT GAAGGCCCAA TTGACCTGGT CTTTGTGATT 
GATGGATCCA AGAGCCTTGG AGAAGAGAAC TTTGAGACTG TGAAGCACTT TGTCACTGGA 
ATCATAGATT CCTTGGCAGT TTCCCCCAAA GCTGCTCGTG TGGGGCTGCT GCAGTATTCC 
ACACAGGTCC GAACAGAGTT TACCCTGAGG GGCTTCAGCT CAGCCAAGGA AATGAAGAAA 
GCCGTGACCC ACATGAAATA CATGGGCAAA GGCTCTATGA CTGGGCTGGC CCTGAAACAC 
ATGTTTGAGA GAAGTTTTAC CCAAGTAGAA GGGGCCAGGC CCCCCTCCAC GCAGGTACCC 
AGAGTAGCCA TCGTGTTCAC CGACGGACGG GCTCAGGATG ATGTCTCTGA GTGGGCCAGT 
AAAGCCAAGG CCAATGGTAT CACTATGTAT GCCGTTGGGG TAGGAAAAGC CATTGAGGAA 
GAACTACAGG AGATTGCCTC TGAGCCCATT GACAAGCATC TCTTCTACGC TGAAGATTTC 
AGCACAATGG GCGAAATAAG TGAAAAGCTG AAAGAAGGCA TCTGTGAAGC TCTAGAAGAC 
TCTGGTGGAA GACAGGACTC AGCAGCATGG GACCTGCCAC AGCAGGCCCA CCAGCCAACA 
GTGCAACATA GATTCCTGTT TGAAGAAGAC AATCTTTCAC GGTCTACACA AAAACTTTTC 
CATTCAACCA AATCTTCAGG AAACCCTTTG GAAGAAAGCC AGGACCAATG CAAATGTGAA 
AACCTTATAC TGTTCCAGAA CGTTGCAAAT GAAGAAGTAA GAAAATTAAC CCAGCGCTTA 
GAAGAAATGA CTCAAAGAAT GGAAGCTTTG GAAAATCGCC TAAAATACAG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MATN2 ( NM_001358780.1 ) cDNA ORF clone, Mus musculus(House mouse) -> NP_001345709.1 Mus musculus matrilin 2 (Matn2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu50659
Clone ID Related Accession (Same CDS sequence)	NM_001358780.1 , XM_006520023.2
Accession Version	NM_001358780.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2871bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Mus musculus(house mouse)
Product	matrilin-2 isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC133101.4, AC144632.4 and AC126028.4. On Dec 9, 2017 this sequence version replaced XM_006520023.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U69262.1, BC005429.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849381 [ECO:0000348] ##Evidence-Data-END##

ATGGAGAAGA TGTTGGTGGG GTGCTTGCTG ATGCTTGGGC AGCTCTTCCT TGTCCTCCCA 
GTTGACGGCA GAGAGCGTCC CCAAGCCAGG TTCCCTTCCA GAGGCCGTCA TGTCCGGATG 
TATCCGCAGA CTGCACTGCT GGAGAGTTCC TGTGAGAATA AGCGGGCAGA TCTGGTGTTC 
ATCATTGACA GCTCCCGAAG TGTCAACACC TATGACTATG CAAAGGTCAA GGAGTTCATT 
CTGGATATCC TGCAGTTCTT GGACATCGGT CCTGATGTTA CCCGAGTAGG TCTGCTCCAA 
TATGGCAGCA CGGTCAAGAA CGAGTTCTCC CTGAAGACCT TTAAGAGGAA GTCTGAGGTG 
GAGAGGGCTG TCAAGAGAAT GAGGCATCTA TCCACTGGCA CCATGACAGG GCTTGCCATC 
CAATATGCCC TCAACATTGC CTTCTCAGAA GCAGAGGGGG CCAGGCCCTT GCGGGAAAAT 
GTGCCACGCA TCATAATGAT TGTGACTGAT GGGAGGCCTC AGGACTCGGT GGCTGAGGTA 
GCTGCCAAGG CCCGGAACAC AGGCATCCTG ATCTTTGCCA TCGGTGTCGG TCAGGTGGAC 
CTGAATACAC TAAAGGCCAT TGGGAGTGAG CCCCACAAGG ACCATGTCTT CCTGGTGGCC 
AATTTCAGCC AGATTGAGTC CTTGACCTCA GTGTTCCAGA ACAAACTGTG CACAGTCCAC 
ATGTGCAGCG TCTTGGAACA CAACTGTGCC CACTTCTGCC TCAACACACC TGGCTCGTAC 
ATCTGCAAGT GCAAGCAAGG GTACATTCTC AGCACGGATC AGAAGACTTG CAGAATCCAG 
GATTTGTGTG CCACAGAGGA CCATGGTTGT GAGCAGCTGT GCGTGAACAT GCTGGGTTCC 
TTTGTCTGCC AGTGCTACAG TGGCTACACC TTGGCCGAGG ACGGGAAGCG ATGTACAGCT 
GTGGACTACT GTGCCTCAGA AAATCATGGA TGTGAACACG AGTGTGTAAA TGCTGAAAGT 
TCCTACCTGT GCCGGTGCCA CGAGGGATTT GCTCTTAACA GCGATAAGAA AACATGCTCA 
AAGATTGACT ATTGTGCCTC TTCAAATCAC GGATGTCAGC ATGAGTGTGT CAATGCCCAG 
ACGTCTGCTC TCTGCCGCTG CCTGAAAGGC TTCATGCTAA ATCCAGACAG GAAAACTTGC 
CGAAGGATCA ACTACTGTGC ACTGAACAAA CCAGGCTGTG AGCATGAGTG TGTGAACACA 
GAGGAGGGTC ACTACTGCCG CTGCCGTCAG GGCTACAATC TGGACCCCAA TGGCAAGACC 
TGCAGCCGGG TGGACCACTG TGCACAGCAG GACCATGGCT GTGAGCAGCT GTGCCTGAAC 
ACAGAGGAGT CCTTTGTCTG CCAGTGCTCA GAAGGCTTCC TTATTAATGA TGACCTCAAG 
ACCTGCTCCA GGGCAGATTA CTGCTTGCTG AGCAACCATG GTTGTGAATA CTCCTGCGTC 
AACACAGACA AATCCTTTGC CTGCCAATGT CCTGAGGGTC ATGTGCTCCG AAGCGATGGG 
AAGACCTGTG CAAAACTGGA CTCTTGTGCT TTGGGGGACC ATGGTTGTGA ACATTCATGT 
GTAAGCAGTG AAGACTCTTT CGTGTGTCAG TGCTTTGAGG GGTACATTCT TCGTGACGAT 
GGGAAGACCT GCAGAAGGAA AGATGTCTGC CAGGATGTTA ACCATGGATG TGAGCACCTT 
TGTGTGAACA GTGGCGAATC ATACGTCTGC AAGTGTCTGG AGGGGTTCAG GCTGGCTGAG 
GATGGGAAGC GCTGCAGGAG GAAGAATGTC TGCAAGTCAA CCCAGCATGG CTGTGAGCAC 
ATGTGTGTGA ACAATGGGAA CTCCTATCTG TGCAGGTGCT CAGAGGGCTT TGTCCTAGCT 
GAGGATGGAA AGCACTGCAA GAGATGCACT GAAGGCCCAA TTGACCTGGT CTTTGTGATT 
GATGGATCCA AGAGCCTTGG AGAAGAGAAC TTTGAGACTG TGAAGCACTT TGTCACTGGA 
ATCATAGATT CCTTGGCAGT TTCCCCCAAA GCTGCTCGTG TGGGGCTGCT GCAGTATTCC 
ACACAGGTCC GAACAGAGTT TACCCTGAGG GGCTTCAGCT CAGCCAAGGA AATGAAGAAA 
GCCGTGACCC ACATGAAATA CATGGGCAAA GGCTCTATGA CTGGGCTGGC CCTGAAACAC 
ATGTTTGAGA GAAGTTTTAC CCAAGTAGAA GGGGCCAGGC CCCCCTCCAC GCAGGTACCC 
AGAGTAGCCA TCGTGTTCAC CGACGGACGG GCTCAGGATG ATGTCTCTGA GTGGGCCAGT 
AAAGCCAAGG CCAATGGTAT CACTATGTAT GCCGTTGGGG TAGGAAAAGC CATTGAGGAA 
GAACTACAGG AGATTGCCTC TGAGCCCATT GACAAGCATC TCTTCTACGC TGAAGATTTC 
AGCACAATGG GCGAAATAAG TGAAAAGCTG AAAGAAGGCA TCTGTGAAGC TCTAGAAGAC 
TCTGGTGGAA GACAGGACTC AGCAGCATGG GACCTGCCAC AGCAGGCCCA CCAGCCAACA 
GAACCTGAGC CAGTCACCAT AAAGATCAAA GACCTACTTT CCTGTTCTAA TTTTGCAGTG 
CAACATAGAT TCCTGTTTGA AGAAGACAAT CTTTCACGGT CTACACAAAA ACTTTTCCAT 
TCAACCAAAT CTTCAGGAAA CCCTTTGGAA GAAAGCCAGG ACCAATGCAA ATGTGAAAAC 
CTTATACTGT TCCAGAACGT TGCAAATGAA GAAGTAAGAA AATTAACCCA GCGCTTAGAA 
GAAATGACTC AAAGAATGGA AGCTTTGGAA AATCGCCTAA AATACAGATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001345709.1
CDS	252..3122
Translation	MEKMLVGCLLMLGQLFLVLPVDGRERPQARFPSRGRHVRMYPQTALLESSCENKRADLVFIIDSSRSVNTYDYAKVKEFILDILQFLDIGPDVTRVGLLQYGSTVKNEFSLKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRIIMIVTDGRPQDSVAEVAAKARNTGILIFAIGVGQVDLNTLKAIGSEPHKDHVFLVANFSQIESLTSVFQNKLCTVHMCSVLEHNCAHFCLNTPGSYICKCKQGYILSTDQKTCRIQDLCATEDHGCEQLCVNMLGSFVCQCYSGYTLAEDGKRCTAVDYCASENHGCEHECVNAESSYLCRCHEGFALNSDKKTCSKIDYCASSNHGCQHECVNAQTSALCRCLKGFMLNPDRKTCRRINYCALNKPGCEHECVNTEEGHYCRCRQGYNLDPNGKTCSRVDHCAQQDHGCEQLCLNTEESFVCQCSEGFLINDDLKTCSRADYCLLSNHGCEYSCVNTDKSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILRDDGKTCRRKDVCQDVNHGCEHLCVNSGESYVCKCLEGFRLAEDGKRCRRKNVCKSTQHGCEHMCVNNGNSYLCRCSEGFVLAEDGKHCKRCTEGPIDLVFVIDGSKSLGEENFETVKHFVTGIIDSLAVSPKAARVGLLQYSTQVRTEFTLRGFSSAKEMKKAVTHMKYMGKGSMTGLALKHMFERSFTQVEGARPPSTQVPRVAIVFTDGRAQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIASEPIDKHLFYAEDFSTMGEISEKLKEGICEALEDSGGRQDSAAWDLPQQAHQPTEPEPVTIKIKDLLSCSNFAVQHRFLFEEDNLSRSTQKLFHSTKSSGNPLEESQDQCKCENLILFQNVANEEVRKLTQRLEEMTQRMEALENRLKYR

Target ORF information:

RefSeq Version	NM_001358780.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus matrilin 2 (Matn2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001358780.1

ORF Insert Sequence:

ATGGAGAAGA TGTTGGTGGG GTGCTTGCTG ATGCTTGGGC AGCTCTTCCT TGTCCTCCCA 
GTTGACGGCA GAGAGCGTCC CCAAGCCAGG TTCCCTTCCA GAGGCCGTCA TGTCCGGATG 
TATCCGCAGA CTGCACTGCT GGAGAGTTCC TGTGAGAATA AGCGGGCAGA TCTGGTGTTC 
ATCATTGACA GCTCCCGAAG TGTCAACACC TATGACTATG CAAAGGTCAA GGAGTTCATT 
CTGGATATCC TGCAGTTCTT GGACATCGGT CCTGATGTTA CCCGAGTAGG TCTGCTCCAA 
TATGGCAGCA CGGTCAAGAA CGAGTTCTCC CTGAAGACCT TTAAGAGGAA GTCTGAGGTG 
GAGAGGGCTG TCAAGAGAAT GAGGCATCTA TCCACTGGCA CCATGACAGG GCTTGCCATC 
CAATATGCCC TCAACATTGC CTTCTCAGAA GCAGAGGGGG CCAGGCCCTT GCGGGAAAAT 
GTGCCACGCA TCATAATGAT TGTGACTGAT GGGAGGCCTC AGGACTCGGT GGCTGAGGTA 
GCTGCCAAGG CCCGGAACAC AGGCATCCTG ATCTTTGCCA TCGGTGTCGG TCAGGTGGAC 
CTGAATACAC TAAAGGCCAT TGGGAGTGAG CCCCACAAGG ACCATGTCTT CCTGGTGGCC 
AATTTCAGCC AGATTGAGTC CTTGACCTCA GTGTTCCAGA ACAAACTGTG CACAGTCCAC 
ATGTGCAGCG TCTTGGAACA CAACTGTGCC CACTTCTGCC TCAACACACC TGGCTCGTAC 
ATCTGCAAGT GCAAGCAAGG GTACATTCTC AGCACGGATC AGAAGACTTG CAGAATCCAG 
GATTTGTGTG CCACAGAGGA CCATGGTTGT GAGCAGCTGT GCGTGAACAT GCTGGGTTCC 
TTTGTCTGCC AGTGCTACAG TGGCTACACC TTGGCCGAGG ACGGGAAGCG ATGTACAGCT 
GTGGACTACT GTGCCTCAGA AAATCATGGA TGTGAACACG AGTGTGTAAA TGCTGAAAGT 
TCCTACCTGT GCCGGTGCCA CGAGGGATTT GCTCTTAACA GCGATAAGAA AACATGCTCA 
AAGATTGACT ATTGTGCCTC TTCAAATCAC GGATGTCAGC ATGAGTGTGT CAATGCCCAG 
ACGTCTGCTC TCTGCCGCTG CCTGAAAGGC TTCATGCTAA ATCCAGACAG GAAAACTTGC 
CGAAGGATCA ACTACTGTGC ACTGAACAAA CCAGGCTGTG AGCATGAGTG TGTGAACACA 
GAGGAGGGTC ACTACTGCCG CTGCCGTCAG GGCTACAATC TGGACCCCAA TGGCAAGACC 
TGCAGCCGGG TGGACCACTG TGCACAGCAG GACCATGGCT GTGAGCAGCT GTGCCTGAAC 
ACAGAGGAGT CCTTTGTCTG CCAGTGCTCA GAAGGCTTCC TTATTAATGA TGACCTCAAG 
ACCTGCTCCA GGGCAGATTA CTGCTTGCTG AGCAACCATG GTTGTGAATA CTCCTGCGTC 
AACACAGACA AATCCTTTGC CTGCCAATGT CCTGAGGGTC ATGTGCTCCG AAGCGATGGG 
AAGACCTGTG CAAAACTGGA CTCTTGTGCT TTGGGGGACC ATGGTTGTGA ACATTCATGT 
GTAAGCAGTG AAGACTCTTT CGTGTGTCAG TGCTTTGAGG GGTACATTCT TCGTGACGAT 
GGGAAGACCT GCAGAAGGAA AGATGTCTGC CAGGATGTTA ACCATGGATG TGAGCACCTT 
TGTGTGAACA GTGGCGAATC ATACGTCTGC AAGTGTCTGG AGGGGTTCAG GCTGGCTGAG 
GATGGGAAGC GCTGCAGGAG GAAGAATGTC TGCAAGTCAA CCCAGCATGG CTGTGAGCAC 
ATGTGTGTGA ACAATGGGAA CTCCTATCTG TGCAGGTGCT CAGAGGGCTT TGTCCTAGCT 
GAGGATGGAA AGCACTGCAA GAGATGCACT GAAGGCCCAA TTGACCTGGT CTTTGTGATT 
GATGGATCCA AGAGCCTTGG AGAAGAGAAC TTTGAGACTG TGAAGCACTT TGTCACTGGA 
ATCATAGATT CCTTGGCAGT TTCCCCCAAA GCTGCTCGTG TGGGGCTGCT GCAGTATTCC 
ACACAGGTCC GAACAGAGTT TACCCTGAGG GGCTTCAGCT CAGCCAAGGA AATGAAGAAA 
GCCGTGACCC ACATGAAATA CATGGGCAAA GGCTCTATGA CTGGGCTGGC CCTGAAACAC 
ATGTTTGAGA GAAGTTTTAC CCAAGTAGAA GGGGCCAGGC CCCCCTCCAC GCAGGTACCC 
AGAGTAGCCA TCGTGTTCAC CGACGGACGG GCTCAGGATG ATGTCTCTGA GTGGGCCAGT 
AAAGCCAAGG CCAATGGTAT CACTATGTAT GCCGTTGGGG TAGGAAAAGC CATTGAGGAA 
GAACTACAGG AGATTGCCTC TGAGCCCATT GACAAGCATC TCTTCTACGC TGAAGATTTC 
AGCACAATGG GCGAAATAAG TGAAAAGCTG AAAGAAGGCA TCTGTGAAGC TCTAGAAGAC 
TCTGGTGGAA GACAGGACTC AGCAGCATGG GACCTGCCAC AGCAGGCCCA CCAGCCAACA 
GAACCTGAGC CAGTCACCAT AAAGATCAAA GACCTACTTT CCTGTTCTAA TTTTGCAGTG 
CAACATAGAT TCCTGTTTGA AGAAGACAAT CTTTCACGGT CTACACAAAA ACTTTTCCAT 
TCAACCAAAT CTTCAGGAAA CCCTTTGGAA GAAAGCCAGG ACCAATGCAA ATGTGAAAAC 
CTTATACTGT TCCAGAACGT TGCAAATGAA GAAGTAAGAA AATTAACCCA GCGCTTAGAA 
GAAATGACTC AAAGAATGGA AGCTTTGGAA AATCGCCTAA AATACAGATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MATN2 ( XM_006520023.2 ) cDNA ORF clone, Mus musculus(House mouse) -> XP_006520086.1 Mus musculus matrilin 2 (Matn2), transcript variant X1, mRNA.

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CloneID	OMu50659
Clone ID Related Accession (Same CDS sequence)	NM_001358780.1 , XM_006520023.2
Accession Version	XM_006520023.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2871bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(House mouse)
Product	matrilin-2 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006520023.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAAGA TGTTGGTGGG GTGCTTGCTG ATGCTTGGGC AGCTCTTCCT TGTCCTCCCA 
GTTGACGGCA GAGAGCGTCC CCAAGCCAGG TTCCCTTCCA GAGGCCGTCA TGTCCGGATG 
TATCCGCAGA CTGCACTGCT GGAGAGTTCC TGTGAGAATA AGCGGGCAGA TCTGGTGTTC 
ATCATTGACA GCTCCCGAAG TGTCAACACC TATGACTATG CAAAGGTCAA GGAGTTCATT 
CTGGATATCC TGCAGTTCTT GGACATCGGT CCTGATGTTA CCCGAGTAGG TCTGCTCCAA 
TATGGCAGCA CGGTCAAGAA CGAGTTCTCC CTGAAGACCT TTAAGAGGAA GTCTGAGGTG 
GAGAGGGCTG TCAAGAGAAT GAGGCATCTA TCCACTGGCA CCATGACAGG GCTTGCCATC 
CAATATGCCC TCAACATTGC CTTCTCAGAA GCAGAGGGGG CCAGGCCCTT GCGGGAAAAT 
GTGCCACGCA TCATAATGAT TGTGACTGAT GGGAGGCCTC AGGACTCGGT GGCTGAGGTA 
GCTGCCAAGG CCCGGAACAC AGGCATCCTG ATCTTTGCCA TCGGTGTCGG TCAGGTGGAC 
CTGAATACAC TAAAGGCCAT TGGGAGTGAG CCCCACAAGG ACCATGTCTT CCTGGTGGCC 
AATTTCAGCC AGATTGAGTC CTTGACCTCA GTGTTCCAGA ACAAACTGTG CACAGTCCAC 
ATGTGCAGCG TCTTGGAACA CAACTGTGCC CACTTCTGCC TCAACACACC TGGCTCGTAC 
ATCTGCAAGT GCAAGCAAGG GTACATTCTC AGCACGGATC AGAAGACTTG CAGAATCCAG 
GATTTGTGTG CCACAGAGGA CCATGGTTGT GAGCAGCTGT GCGTGAACAT GCTGGGTTCC 
TTTGTCTGCC AGTGCTACAG TGGCTACACC TTGGCCGAGG ACGGGAAGCG ATGTACAGCT 
GTGGACTACT GTGCCTCAGA AAATCATGGA TGTGAACACG AGTGTGTAAA TGCTGAAAGT 
TCCTACCTGT GCCGGTGCCA CGAGGGATTT GCTCTTAACA GCGATAAGAA AACATGCTCA 
AAGATTGACT ATTGTGCCTC TTCAAATCAC GGATGTCAGC ATGAGTGTGT CAATGCCCAG 
ACGTCTGCTC TCTGCCGCTG CCTGAAAGGC TTCATGCTAA ATCCAGACAG GAAAACTTGC 
CGAAGGATCA ACTACTGTGC ACTGAACAAA CCAGGCTGTG AGCATGAGTG TGTGAACACA 
GAGGAGGGTC ACTACTGCCG CTGCCGTCAG GGCTACAATC TGGACCCCAA TGGCAAGACC 
TGCAGCCGGG TGGACCACTG TGCACAGCAG GACCATGGCT GTGAGCAGCT GTGCCTGAAC 
ACAGAGGAGT CCTTTGTCTG CCAGTGCTCA GAAGGCTTCC TTATTAATGA TGACCTCAAG 
ACCTGCTCCA GGGCAGATTA CTGCTTGCTG AGCAACCATG GTTGTGAATA CTCCTGCGTC 
AACACAGACA AATCCTTTGC CTGCCAATGT CCTGAGGGTC ATGTGCTCCG AAGCGATGGG 
AAGACCTGTG CAAAACTGGA CTCTTGTGCT TTGGGGGACC ATGGTTGTGA ACATTCATGT 
GTAAGCAGTG AAGACTCTTT CGTGTGTCAG TGCTTTGAGG GGTACATTCT TCGTGACGAT 
GGGAAGACCT GCAGAAGGAA AGATGTCTGC CAGGATGTTA ACCATGGATG TGAGCACCTT 
TGTGTGAACA GTGGCGAATC ATACGTCTGC AAGTGTCTGG AGGGGTTCAG GCTGGCTGAG 
GATGGGAAGC GCTGCAGGAG GAAGAATGTC TGCAAGTCAA CCCAGCATGG CTGTGAGCAC 
ATGTGTGTGA ACAATGGGAA CTCCTATCTG TGCAGGTGCT CAGAGGGCTT TGTCCTAGCT 
GAGGATGGAA AGCACTGCAA GAGATGCACT GAAGGCCCAA TTGACCTGGT CTTTGTGATT 
GATGGATCCA AGAGCCTTGG AGAAGAGAAC TTTGAGACTG TGAAGCACTT TGTCACTGGA 
ATCATAGATT CCTTGGCAGT TTCCCCCAAA GCTGCTCGTG TGGGGCTGCT GCAGTATTCC 
ACACAGGTCC GAACAGAGTT TACCCTGAGG GGCTTCAGCT CAGCCAAGGA AATGAAGAAA 
GCCGTGACCC ACATGAAATA CATGGGCAAA GGCTCTATGA CTGGGCTGGC CCTGAAACAC 
ATGTTTGAGA GAAGTTTTAC CCAAGTAGAA GGGGCCAGGC CCCCCTCCAC GCAGGTACCC 
AGAGTAGCCA TCGTGTTCAC CGACGGACGG GCTCAGGATG ATGTCTCTGA GTGGGCCAGT 
AAAGCCAAGG CCAATGGTAT CACTATGTAT GCCGTTGGGG TAGGAAAAGC CATTGAGGAA 
GAACTACAGG AGATTGCCTC TGAGCCCATT GACAAGCATC TCTTCTACGC TGAAGATTTC 
AGCACAATGG GCGAAATAAG TGAAAAGCTG AAAGAAGGCA TCTGTGAAGC TCTAGAAGAC 
TCTGGTGGAA GACAGGACTC AGCAGCATGG GACCTGCCAC AGCAGGCCCA CCAGCCAACA 
GAACCTGAGC CAGTCACCAT AAAGATCAAA GACCTACTTT CCTGTTCTAA TTTTGCAGTG 
CAACATAGAT TCCTGTTTGA AGAAGACAAT CTTTCACGGT CTACACAAAA ACTTTTCCAT 
TCAACCAAAT CTTCAGGAAA CCCTTTGGAA GAAAGCCAGG ACCAATGCAA ATGTGAAAAC 
CTTATACTGT TCCAGAACGT TGCAAATGAA GAAGTAAGAA AATTAACCCA GCGCTTAGAA 
GAAATGACTC AAAGAATGGA AGCTTTGGAA AATCGCCTAA AATACAGATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006520086.1
CDS	279..3149
Translation	MEKMLVGCLLMLGQLFLVLPVDGRERPQARFPSRGRHVRMYPQTALLESSCENKRADLVFIIDSSRSVNTYDYAKVKEFILDILQFLDIGPDVTRVGLLQYGSTVKNEFSLKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRIIMIVTDGRPQDSVAEVAAKARNTGILIFAIGVGQVDLNTLKAIGSEPHKDHVFLVANFSQIESLTSVFQNKLCTVHMCSVLEHNCAHFCLNTPGSYICKCKQGYILSTDQKTCRIQDLCATEDHGCEQLCVNMLGSFVCQCYSGYTLAEDGKRCTAVDYCASENHGCEHECVNAESSYLCRCHEGFALNSDKKTCSKIDYCASSNHGCQHECVNAQTSALCRCLKGFMLNPDRKTCRRINYCALNKPGCEHECVNTEEGHYCRCRQGYNLDPNGKTCSRVDHCAQQDHGCEQLCLNTEESFVCQCSEGFLINDDLKTCSRADYCLLSNHGCEYSCVNTDKSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILRDDGKTCRRKDVCQDVNHGCEHLCVNSGESYVCKCLEGFRLAEDGKRCRRKNVCKSTQHGCEHMCVNNGNSYLCRCSEGFVLAEDGKHCKRCTEGPIDLVFVIDGSKSLGEENFETVKHFVTGIIDSLAVSPKAARVGLLQYSTQVRTEFTLRGFSSAKEMKKAVTHMKYMGKGSMTGLALKHMFERSFTQVEGARPPSTQVPRVAIVFTDGRAQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIASEPIDKHLFYAEDFSTMGEISEKLKEGICEALEDSGGRQDSAAWDLPQQAHQPTEPEPVTIKIKDLLSCSNFAVQHRFLFEEDNLSRSTQKLFHSTKSSGNPLEESQDQCKCENLILFQNVANEEVRKLTQRLEEMTQRMEALENRLKYR

Target ORF information:

RefSeq Version	XM_006520023.2
Organism	Mus musculus(House mouse)
Definition	Mus musculus matrilin 2 (Matn2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006520023.2

ORF Insert Sequence:

ATGGAGAAGA TGTTGGTGGG GTGCTTGCTG ATGCTTGGGC AGCTCTTCCT TGTCCTCCCA 
GTTGACGGCA GAGAGCGTCC CCAAGCCAGG TTCCCTTCCA GAGGCCGTCA TGTCCGGATG 
TATCCGCAGA CTGCACTGCT GGAGAGTTCC TGTGAGAATA AGCGGGCAGA TCTGGTGTTC 
ATCATTGACA GCTCCCGAAG TGTCAACACC TATGACTATG CAAAGGTCAA GGAGTTCATT 
CTGGATATCC TGCAGTTCTT GGACATCGGT CCTGATGTTA CCCGAGTAGG TCTGCTCCAA 
TATGGCAGCA CGGTCAAGAA CGAGTTCTCC CTGAAGACCT TTAAGAGGAA GTCTGAGGTG 
GAGAGGGCTG TCAAGAGAAT GAGGCATCTA TCCACTGGCA CCATGACAGG GCTTGCCATC 
CAATATGCCC TCAACATTGC CTTCTCAGAA GCAGAGGGGG CCAGGCCCTT GCGGGAAAAT 
GTGCCACGCA TCATAATGAT TGTGACTGAT GGGAGGCCTC AGGACTCGGT GGCTGAGGTA 
GCTGCCAAGG CCCGGAACAC AGGCATCCTG ATCTTTGCCA TCGGTGTCGG TCAGGTGGAC 
CTGAATACAC TAAAGGCCAT TGGGAGTGAG CCCCACAAGG ACCATGTCTT CCTGGTGGCC 
AATTTCAGCC AGATTGAGTC CTTGACCTCA GTGTTCCAGA ACAAACTGTG CACAGTCCAC 
ATGTGCAGCG TCTTGGAACA CAACTGTGCC CACTTCTGCC TCAACACACC TGGCTCGTAC 
ATCTGCAAGT GCAAGCAAGG GTACATTCTC AGCACGGATC AGAAGACTTG CAGAATCCAG 
GATTTGTGTG CCACAGAGGA CCATGGTTGT GAGCAGCTGT GCGTGAACAT GCTGGGTTCC 
TTTGTCTGCC AGTGCTACAG TGGCTACACC TTGGCCGAGG ACGGGAAGCG ATGTACAGCT 
GTGGACTACT GTGCCTCAGA AAATCATGGA TGTGAACACG AGTGTGTAAA TGCTGAAAGT 
TCCTACCTGT GCCGGTGCCA CGAGGGATTT GCTCTTAACA GCGATAAGAA AACATGCTCA 
AAGATTGACT ATTGTGCCTC TTCAAATCAC GGATGTCAGC ATGAGTGTGT CAATGCCCAG 
ACGTCTGCTC TCTGCCGCTG CCTGAAAGGC TTCATGCTAA ATCCAGACAG GAAAACTTGC 
CGAAGGATCA ACTACTGTGC ACTGAACAAA CCAGGCTGTG AGCATGAGTG TGTGAACACA 
GAGGAGGGTC ACTACTGCCG CTGCCGTCAG GGCTACAATC TGGACCCCAA TGGCAAGACC 
TGCAGCCGGG TGGACCACTG TGCACAGCAG GACCATGGCT GTGAGCAGCT GTGCCTGAAC 
ACAGAGGAGT CCTTTGTCTG CCAGTGCTCA GAAGGCTTCC TTATTAATGA TGACCTCAAG 
ACCTGCTCCA GGGCAGATTA CTGCTTGCTG AGCAACCATG GTTGTGAATA CTCCTGCGTC 
AACACAGACA AATCCTTTGC CTGCCAATGT CCTGAGGGTC ATGTGCTCCG AAGCGATGGG 
AAGACCTGTG CAAAACTGGA CTCTTGTGCT TTGGGGGACC ATGGTTGTGA ACATTCATGT 
GTAAGCAGTG AAGACTCTTT CGTGTGTCAG TGCTTTGAGG GGTACATTCT TCGTGACGAT 
GGGAAGACCT GCAGAAGGAA AGATGTCTGC CAGGATGTTA ACCATGGATG TGAGCACCTT 
TGTGTGAACA GTGGCGAATC ATACGTCTGC AAGTGTCTGG AGGGGTTCAG GCTGGCTGAG 
GATGGGAAGC GCTGCAGGAG GAAGAATGTC TGCAAGTCAA CCCAGCATGG CTGTGAGCAC 
ATGTGTGTGA ACAATGGGAA CTCCTATCTG TGCAGGTGCT CAGAGGGCTT TGTCCTAGCT 
GAGGATGGAA AGCACTGCAA GAGATGCACT GAAGGCCCAA TTGACCTGGT CTTTGTGATT 
GATGGATCCA AGAGCCTTGG AGAAGAGAAC TTTGAGACTG TGAAGCACTT TGTCACTGGA 
ATCATAGATT CCTTGGCAGT TTCCCCCAAA GCTGCTCGTG TGGGGCTGCT GCAGTATTCC 
ACACAGGTCC GAACAGAGTT TACCCTGAGG GGCTTCAGCT CAGCCAAGGA AATGAAGAAA 
GCCGTGACCC ACATGAAATA CATGGGCAAA GGCTCTATGA CTGGGCTGGC CCTGAAACAC 
ATGTTTGAGA GAAGTTTTAC CCAAGTAGAA GGGGCCAGGC CCCCCTCCAC GCAGGTACCC 
AGAGTAGCCA TCGTGTTCAC CGACGGACGG GCTCAGGATG ATGTCTCTGA GTGGGCCAGT 
AAAGCCAAGG CCAATGGTAT CACTATGTAT GCCGTTGGGG TAGGAAAAGC CATTGAGGAA 
GAACTACAGG AGATTGCCTC TGAGCCCATT GACAAGCATC TCTTCTACGC TGAAGATTTC 
AGCACAATGG GCGAAATAAG TGAAAAGCTG AAAGAAGGCA TCTGTGAAGC TCTAGAAGAC 
TCTGGTGGAA GACAGGACTC AGCAGCATGG GACCTGCCAC AGCAGGCCCA CCAGCCAACA 
GAACCTGAGC CAGTCACCAT AAAGATCAAA GACCTACTTT CCTGTTCTAA TTTTGCAGTG 
CAACATAGAT TCCTGTTTGA AGAAGACAAT CTTTCACGGT CTACACAAAA ACTTTTCCAT 
TCAACCAAAT CTTCAGGAAA CCCTTTGGAA GAAAGCCAGG ACCAATGCAA ATGTGAAAAC 
CTTATACTGT TCCAGAACGT TGCAAATGAA GAAGTAAGAA AATTAACCCA GCGCTTAGAA 
GAAATGACTC AAAGAATGGA AGCTTTGGAA AATCGCCTAA AATACAGATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Matrilin-2 regulates proliferation, apoptosis and cell cycle during radiation-induced injury in HPAEpiC cell.
Biochemical and biophysical research communications485(3)577-583(2017 04)
Luo J,Zhang M,Huang H,Wang Y,Yuan X,Ma S,Liu J,Zhou S,Zhang S

Absence of collagen IX accelerates hypertrophic differentiation in the embryonic mouse spine through a disturbance of the Ihh-PTHrP feedback loop.
Cell and tissue research367(2)359-367(2017 Feb)
Kamper M,Paulsson M,Zaucke F

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.
Scientific reports740495(2017 Jan)
Naba A,Clauser KR,Mani DR,Carr SA,Hynes RO

The extracellular matrix protein matrilin-2 induces post-burn inflammatory responses as an endogenous danger signal.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]64(10)833-9(2015 Oct)
Chi Y,Chai J,Xu C,Luo H,Zhang Q

Axonally derived matrilin-2 induces proinflammatory responses that exacerbate autoimmune neuroinflammation.
The Journal of clinical investigation124(11)5042-56(2014 Nov)
Jonas A,Thiem S,Kuhlmann T,Wagener R,Aszodi A,Nowell C,Hagemeier K,Laverick L,Perreau V,Jokubaitis V,Emery B,Kilpatrick T,Butzkueven H,Gresle M

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MATN2 cDNA ORF clone, Mus musculus(House mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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