Fv1 cDNA ORF clone, Mus musculus(house mouse)

Expression levels of Fv1: effects on retroviral restriction specificities.
Li W, Yap MW, Voss V, Stoye JP
Retrovirology13(1)42(2016 06)

Structural studies of postentry restriction factors reveal antiparallel dimers that enable avid binding to the HIV-1 capsid lattice.
Goldstone DC, Walker PA, Calder LJ, Coombs PJ, Kirkpatrick J, Ball NJ, Hilditch L, Yap MW, Rosenthal PB, Stoye JP, Taylor IA
Proceedings of the National Academy of Sciences of the United States of America111(26)9609-14(2014 Jul)

Evolution of the retroviral restriction gene Fv1: inhibition of non-MLV retroviruses.
Yap MW, Colbeck E, Ellis SA, Stoye JP
PLoS pathogens10(3)e1003968(2014 Mar)

data indicate that for some but not all Fv1 proteins, gain of restriction activities could be achieved by increasing the expression level of Fv1; however such a concentration dependent effect is not seen with most Fv1s and cannot explain the recently reported activities against non-MLVs
Title: Expression levels of Fv1: effects on retroviral restriction specificities.

The antiparallel organization of the NtD regions of Fv1 and Trim5alpha dimers correctly positions C-terminal specificity and N-terminal effector domains and facilitates stable binding to adjacent capsid hexamers in viral cores.
Title: Structural studies of postentry restriction factors reveal antiparallel dimers that enable avid binding to the HIV-1 capsid lattice.

These results support the hypothesis that Fv1 defended mice against waves of retroviral infection
Title: Evolution of the retroviral restriction gene Fv1: inhibition of non-MLV retroviruses.

Ordered assembly of murine leukemia virus capsid protein on lipid nanotubes directs specific binding by the restriction factor, Fv1.
Title: Ordered assembly of murine leukemia virus capsid protein on lipid nanotubes directs specific binding by the restriction factor, Fv1.

Virus with deletion of 114His in the capsid gene failed to replicate in Fv1-expressing cells.
Title: Generation and characterization of a stable full-length ecotropic murine leukemia virus molecular clone that produces novel phenotypes to Fv1 restriction.