Fgf18 cDNA ORF clone, Mus musculus(house mouse)

Lack of Fgf18 causes abnormal clustering of motor nerve terminals at the neuromuscular junction with reduced acetylcholine receptor clusters.
Ito K, Ohkawara B, Yagi H, Nakashima H, Tsushima M, Ota K, Konishi H, Masuda A, Imagama S, Kiyama H, Ishiguro N, Ohno K
Scientific reports8(1)434(2018 Jan)

Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior.
Jung EM, Moffat JJ, Liu J, Dravid SM, Gurumurthy CB, Kim WY
Nature neuroscience20(12)1694-1707(2017 Dec)

An Atoh1-S193A Phospho-Mutant Allele Causes Hearing Deficits and Motor Impairment.
Xie WR, Jen HI, Seymour ML, Yeh SY, Pereira FA, Groves AK, Klisch TJ, Zoghbi HY
The Journal of neuroscience : the official journal of the Society for Neuroscience37(36)8583-8594(2017 09)

Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice.
Zhang H, Kamiya N, Tsuji T, Takeda H, Scott G, Rajderkar S, Ray MK, Mochida Y, Allen B, Lefebvre V, Hung IH, Ornitz DM, Kunieda T, Mishina Y
PLoS genetics12(12)e1006510(2016 Dec)

Elevation of FGF signaling, mainly due to increased Fgf18 expression upon inactivation of Evc2 in the perichondrium, critically contributes to the pathogenesis of limb dwarfism. The limb dwarfism phenotype is partially rescued by inactivation of one allele of Fgf18 in the Evc2 mutant mice
Title: Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice.

Loss of alleles of Fgf9 and Fgf18 also affect the expression of genes encoding other key intrinsic skeletal regulators, including IHH, PTHLH (PTHrP), and RUNX2, revealing potential direct, indirect, and compensatory mechanisms to coordinate chondrogenesis and osteogenesis.
Title: A combined series of Fgf9 and Fgf18 mutant alleles identifies unique and redundant roles in skeletal development.

retinoic acid is produced by pulmonary endothelial cells and regulates pulmonary angiogenesis and elastin synthesis by induction of VEGF-A and fibroblast growth factor (FGF)-18, respectively
Title: VEGF and endothelium-derived retinoic acid regulate lung vascular and alveolar development.

novel Shh-Foxf-Fgf18-Shh circuit in the palate development molecular network, in which Foxf1 and Foxf2 regulate palatal shelf growth downstream of Shh signaling, at least in part, by repressing Fgf18 expression
Title: A Shh-Foxf-Fgf18-Shh Molecular Circuit Regulating Palate Development.

post-natal induction of chondrocyte autophagy is mediated by the growth factor FGF18 through FGFR4 and JNK-dependent activation of the autophagy initiation complex VPS34-beclin-1
Title: FGF signalling regulates bone growth through autophagy.