Fcer1a cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fcer1a
Entrez Gene ID	14125
Full Name	Fc receptor, IgE, high affinity I, alpha polypeptide
Synonyms	FcERI,Fce1a,Fcr-5,fcepsilonri
General protein information	Preferred Names Fc receptor, IgE, high affinity I, alpha polypeptide Names high affinity immunoglobulin epsilon receptor subunit alpha fc-epsilon RI-alpha igE Fc receptor subunit alpha
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1 H3\|1 80.33 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_010184.2	NP_034314.2	high affinity immunoglobulin epsilon receptor subunit alpha precursor
XM_006496655.1	XP_006496718.1	high affinity immunoglobulin epsilon receptor subunit alpha isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	FCER1A	NP_001093780.1
Pan troglodytes (chimpanzee)	FCER1A	XP_001170670.2
	FCER1A	XP_001117218.2
Homo sapiens (human)	FCER1A	NP_001992.1
Canis lupus familiaris (dog)	FCER1A	NP_001104236.1
Mus musculus (house mouse)	Fcer1a	NP_034314.2
Rattus norvegicus (Norway rat)	Fcer1a	NP_036856.1

Gene Ontology
Bibliography

Related articles in PubMed

IgE induces hypotension in asthma mice by down-regulating vascular NCX1 expression through activating MiR-212-5p.
Zhao H, Song X, Yan L, Ren M, Cui X, Li Y, Gao R, Zhang W, Liu M, Liu B, Hu Y, Wang J
Biochimica et biophysica acta1864(1)189-196(2018 Jan)

House Dust Mite-Induced Allergic Airway Disease Is Independent of IgE and Fc?RI?.
McKnight CG, Jude JA, Zhu Z, Panettieri RA Jr, Finkelman FD
American journal of respiratory cell and molecular biology57(6)674-682(2017 Dec)

Spontaneous food allergy in Was
Lexmond WS, Goettel JA, Sallis BF, McCann K, Rings EHHM, Jensen-Jarolim E, Nurko S, Snapper SB, Fiebiger E
Allergy72(12)1916-1924(2017 Dec)

Complete structure of the mouse mast cell receptor for IgE (Fc epsilon RI) and surface expression of chimeric receptors (rat-mouse-human) on transfected cells.
Ra C, Jouvin MH, Kinet JP
The Journal of biological chemistry264(26)15323-7(1989 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

House Dust Mite-Induced Allergic Airway Disease Is Independent of IgE and FcepsilonRIalpha.
Title: House Dust Mite-Induced Allergic Airway Disease Is Independent of IgE and Fc?RI?.

this study shows that mast cells co-cultured with macrophages alter protein expression of both cell types, and that mast cells transfer FceRI-encompassed cellular regions directly to macrophages during Francisella tularensis
Title: Contribution of Fc?RI-associated vesicles to mast cell-macrophage communication following Francisella tularensis infection.

Tim-3 acts at a receptor-proximal point to enhance Lyn kinase-dependent signaling pathways that modulate both immediate-phase degranulation and late-phase cytokine production downstream of FcepsilonRI ligation.
Title: Tim-3 enhances Fc?RI-proximal signaling to modulate mast cell activation.

Data indicate that white adipose tissue from IgE receptor FcR1-deficient Fcer1a(-/-) mice showed an increased expression of CCAAT-enhancer-binding protein-alpha (C-EBPalpha) and peroxisome proliferator-activated receptor-gamma (PPARgamma).
Title: Deficiency of Fc?R1 Increases Body Weight Gain but Improves Glucose Tolerance in Diet-Induced Obese Mice.

Tetraspanin CD151 Is a Negative Regulator of FcepsilonRI-Mediated Mast Cell Activation
Title: Tetraspanin CD151 Is a Negative Regulator of Fc?RI-Mediated Mast Cell Activation.

The following Fcer1a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fcer1a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu28624	XM_006496655.1 Latest version!	Mus musculus Fc receptor, IgE, high affinity I, alpha polypeptide (Fcer1a), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu22630	NM_010184.2 Latest version!	Mus musculus Fc receptor, IgE, high affinity I, alpha polypeptide (Fcer1a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fcer1a ( XM_006496655.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006496718.1 Mus musculus Fc receptor, IgE, high affinity I, alpha polypeptide (Fcer1a), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu28624
Clone ID Related Accession (Same CDS sequence)	XM_006496655.1
Accession Version	XM_006496655.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 732bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	high affinity immunoglobulin epsilon receptor subunit alpha isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCACTG GAAGGTCTGC CCAGCTGTGC CTAGCACTGC TGTTCATGTC CACTGAGAAA 
TCTGTACTGA CCTTGGACCC ACCATGGATT AGAATATTTA CAGGAGAGAA AGTGACCCTT 
TCCTGCTATG GGAACAATCA CCTTCAAATG AACTCTACTA CTAAATGGAT CCACAATGGT 
ACCGTCTCTG AGGTGAACTC TTCACATTTG GTCATTGTGA GTGCCACCGT TCAAGACAGT 
GGAAAATACA TATGTCAGAA GCAAGGATTG TTTAAGAGTA AACCTGTGTA CTTGAATGTA 
ACGCAAGATT GGCTGCTCCT TCAGACATCT GCTGACATGG TCTTAGTCCA TGGATCCTTT 
GACATCAGAT GCCATGGCTG GAAGAACTGG AATGTCCGCA AGGTGATCTA CTACAGGAAT 
GACCATGCTT TCAACTACAG TTATGAGAGC CCCGTCTCCA TTAGAGAGGC CACACTGAAT 
GACAGTGGCA CCTACCACTG CAAGGGCTAT CTTAGGCAGG TGAAATATGA ATCTGACAAA 
TTCAGAATTG CTGTAGTAAA AGCTTACAAA TGCAAGTATT ATTGGCTACA ACTAATTTTC 
CCATTGTTGG TGGCGATTCT GTTTGCTGTG GACACGGGGT TATTGCTCTC AACCGAAGAA 
CAGTTCAAAT CAGTCTTGGA GATTCAGAAG ACTGGAAAAT ACAAGAAAGT TGAAACCGAA 
CTCCTAACCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006496718.1
CDS	58..789
Translation	MVTGRSAQLCLALLFMSTEKSVLTLDPPWIRIFTGEKVTLSCYGNNHLQMNSTTKWIHNGTVSEVNSSHLVIVSATVQDSGKYICQKQGLFKSKPVYLNVTQDWLLLQTSADMVLVHGSFDIRCHGWKNWNVRKVIYYRNDHAFNYSYESPVSIREATLNDSGTYHCKGYLRQVKYESDKFRIAVVKAYKCKYYWLQLIFPLLVAILFAVDTGLLLSTEEQFKSVLEIQKTGKYKKVETELLT

Target ORF information:

RefSeq Version	XM_006496655.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus Fc receptor, IgE, high affinity I, alpha polypeptide (Fcer1a), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006496655.1

ORF Insert Sequence:

ATGGTCACTG GAAGGTCTGC CCAGCTGTGC CTAGCACTGC TGTTCATGTC CACTGAGAAA 
TCTGTACTGA CCTTGGACCC ACCATGGATT AGAATATTTA CAGGAGAGAA AGTGACCCTT 
TCCTGCTATG GGAACAATCA CCTTCAAATG AACTCTACTA CTAAATGGAT CCACAATGGT 
ACCGTCTCTG AGGTGAACTC TTCACATTTG GTCATTGTGA GTGCCACCGT TCAAGACAGT 
GGAAAATACA TATGTCAGAA GCAAGGATTG TTTAAGAGTA AACCTGTGTA CTTGAATGTA 
ACGCAAGATT GGCTGCTCCT TCAGACATCT GCTGACATGG TCTTAGTCCA TGGATCCTTT 
GACATCAGAT GCCATGGCTG GAAGAACTGG AATGTCCGCA AGGTGATCTA CTACAGGAAT 
GACCATGCTT TCAACTACAG TTATGAGAGC CCCGTCTCCA TTAGAGAGGC CACACTGAAT 
GACAGTGGCA CCTACCACTG CAAGGGCTAT CTTAGGCAGG TGAAATATGA ATCTGACAAA 
TTCAGAATTG CTGTAGTAAA AGCTTACAAA TGCAAGTATT ATTGGCTACA ACTAATTTTC 
CCATTGTTGG TGGCGATTCT GTTTGCTGTG GACACGGGGT TATTGCTCTC AACCGAAGAA 
CAGTTCAAAT CAGTCTTGGA GATTCAGAAG ACTGGAAAAT ACAAGAAAGT TGAAACCGAA 
CTCCTAACCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fcer1a ( NM_010184.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034314.2 Mus musculus Fc receptor, IgE, high affinity I, alpha polypeptide (Fcer1a), mRNA.

Price & Availability↑

CloneID	OMu22630
Clone ID Related Accession (Same CDS sequence)	NM_010184.2
Accession Version	NM_010184.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 753bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	high affinity immunoglobulin epsilon receptor subunit alpha precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ142191.1, BC125455.1, CJ142154.1, J05018.1 and BY585428.1. On Apr 15, 2009 this sequence version replaced NM_010184.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: J05018.1, BC125455.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849380, SAMN00849387 [ECO:0000350] ##Evidence-Data-END##

ATGGTCACTG GAAGGTCTGC CCAGCTGTGC CTAGCACTGC TGTTCATGTC TCTTGATGTC 
ATTCTGACAG CCACTGAGAA ATCTGTACTG ACCTTGGACC CACCATGGAT TAGAATATTT 
ACAGGAGAGA AAGTGACCCT TTCCTGCTAT GGGAACAATC ACCTTCAAAT GAACTCTACT 
ACTAAATGGA TCCACAATGG TACCGTCTCT GAGGTGAACT CTTCACATTT GGTCATTGTG 
AGTGCCACCG TTCAAGACAG TGGAAAATAC ATATGTCAGA AGCAAGGATT GTTTAAGAGT 
AAACCTGTGT ACTTGAATGT AACGCAAGAT TGGCTGCTCC TTCAGACATC TGCTGACATG 
GTCTTAGTCC ATGGATCCTT TGACATCAGA TGCCATGGCT GGAAGAACTG GAATGTCCGC 
AAGGTGATCT ACTACAGGAA TGACCATGCT TTCAACTACA GTTATGAGAG CCCCGTCTCC 
ATTAGAGAGG CCACACTGAA TGACAGTGGC ACCTACCACT GCAAGGGCTA TCTTAGGCAG 
GTGAAATATG AATCTGACAA ATTCAGAATT GCTGTAGTAA AAGCTTACAA ATGCAAGTAT 
TATTGGCTAC AACTAATTTT CCCATTGTTG GTGGCGATTC TGTTTGCTGT GGACACGGGG 
TTATTGCTCT CAACCGAAGA ACAGTTCAAA TCAGTCTTGG AGATTCAGAA GACTGGAAAA 
TACAAGAAAG TTGAAACCGA ACTCCTAACC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034314.2
CDS	55..807
Translation	MVTGRSAQLCLALLFMSLDVILTATEKSVLTLDPPWIRIFTGEKVTLSCYGNNHLQMNSTTKWIHNGTVSEVNSSHLVIVSATVQDSGKYICQKQGLFKSKPVYLNVTQDWLLLQTSADMVLVHGSFDIRCHGWKNWNVRKVIYYRNDHAFNYSYESPVSIREATLNDSGTYHCKGYLRQVKYESDKFRIAVVKAYKCKYYWLQLIFPLLVAILFAVDTGLLLSTEEQFKSVLEIQKTGKYKKVETELLT

Target ORF information:

RefSeq Version	NM_010184.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus Fc receptor, IgE, high affinity I, alpha polypeptide (Fcer1a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010184.2

ORF Insert Sequence:

ATGGTCACTG GAAGGTCTGC CCAGCTGTGC CTAGCACTGC TGTTCATGTC TCTTGATGTC 
ATTCTGACAG CCACTGAGAA ATCTGTACTG ACCTTGGACC CACCATGGAT TAGAATATTT 
ACAGGAGAGA AAGTGACCCT TTCCTGCTAT GGGAACAATC ACCTTCAAAT GAACTCTACT 
ACTAAATGGA TCCACAATGG TACCGTCTCT GAGGTGAACT CTTCACATTT GGTCATTGTG 
AGTGCCACCG TTCAAGACAG TGGAAAATAC ATATGTCAGA AGCAAGGATT GTTTAAGAGT 
AAACCTGTGT ACTTGAATGT AACGCAAGAT TGGCTGCTCC TTCAGACATC TGCTGACATG 
GTCTTAGTCC ATGGATCCTT TGACATCAGA TGCCATGGCT GGAAGAACTG GAATGTCCGC 
AAGGTGATCT ACTACAGGAA TGACCATGCT TTCAACTACA GTTATGAGAG CCCCGTCTCC 
ATTAGAGAGG CCACACTGAA TGACAGTGGC ACCTACCACT GCAAGGGCTA TCTTAGGCAG 
GTGAAATATG AATCTGACAA ATTCAGAATT GCTGTAGTAA AAGCTTACAA ATGCAAGTAT 
TATTGGCTAC AACTAATTTT CCCATTGTTG GTGGCGATTC TGTTTGCTGT GGACACGGGG 
TTATTGCTCT CAACCGAAGA ACAGTTCAAA TCAGTCTTGG AGATTCAGAA GACTGGAAAA 
TACAAGAAAG TTGAAACCGA ACTCCTAACC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

IgE induces hypotension in asthma mice by down-regulating vascular NCX1 expression through activating MiR-212-5p.
Biochimica et biophysica acta1864(1)189-196(2018 Jan)
Zhao H,Song X,Yan L,Ren M,Cui X,Li Y,Gao R,Zhang W,Liu M,Liu B,Hu Y,Wang J

House Dust Mite-Induced Allergic Airway Disease Is Independent of IgE and Fc?RI?.
American journal of respiratory cell and molecular biology57(6)674-682(2017 Dec)
McKnight CG,Jude JA,Zhu Z,Panettieri RA Jr,Finkelman FD

Spontaneous food allergy in Was
Allergy72(12)1916-1924(2017 Dec)
Lexmond WS,Goettel JA,Sallis BF,McCann K,Rings EHHM,Jensen-Jarolim E,Nurko S,Snapper SB,Fiebiger E

Complete structure of the mouse mast cell receptor for IgE (Fc epsilon RI) and surface expression of chimeric receptors (rat-mouse-human) on transfected cells.
The Journal of biological chemistry264(26)15323-7(1989 Sep)
Ra C,Jouvin MH,Kinet JP

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Fcer1a cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報