Ctsd cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ctsd
Entrez Gene ID	13033
Full Name	cathepsin D
Synonyms	CD,CatD
General protein information	Preferred Names cathepsin D Names cathepsin D
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7\|7 F5

mRNA and Protein(s)

mRNA	Protein	Name
NM_009983.3	NP_034113.1	cathepsin D precursor
NM_009983.2	NP_034113.1	cathepsin D precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	CTSD	NP_001900.1
Bos taurus (cattle)	CTSD	NP_001159993.1
Rattus norvegicus (Norway rat)	Ctsd	NP_599161.2
Gallus gallus (chicken)	CTSD	NP_990508.1
Danio rerio (zebrafish)	ctsd	NP_571785.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003277	XP_307784.1
Arabidopsis thaliana (thale cress)	AT1G62290	NP_001031219.1
Mus musculus (house mouse)	Ctsd	NP_034113.1
Caenorhabditis elegans (roundworm)	asp-4	NP_510191.1
Saccharomyces cerevisiae (baker's yeast)	PEP4	NP_015171.1
Xenopus tropicalis (tropical clawed frog)	ctsd	NP_988964.1
Xenopus tropicalis (tropical clawed frog)	LOC613063	NP_001136375.1
Canis lupus familiaris (dog)	CTSD	NP_001020792.1
Magnaporthe oryzae (rice blast fungus)	MGG_00922	XP_003718037.1
Neurospora crassa	NCU02273	XP_959917.1
Arabidopsis thaliana (thale cress)	APA1	NP_172655.1
Oryza sativa (rice)	Os05g0567100	NP_001056348.1
Xenopus tropicalis (tropical clawed frog)	LOC101735147	XP_004914286.1
	CTSD	XP_001091601.1
Drosophila melanogaster (fruit fly)	cathD	NP_652013.1
Kluyveromyces lactis	KLLA0D05929g	XP_453326.1
Oryza sativa (rice)	Os01g0663400	NP_001043786.1
Xenopus tropicalis (tropical clawed frog)	LOC100489529	XP_002938948.2

Gene Ontology
Bibliography

Related articles in PubMed

Cathepsin D regulates cathepsin B activation and disease severity predominantly in inflammatory cells during experimental pancreatitis.
Aghdassi AA, John DS, Sendler M, Weiss FU, Reinheckel T, Mayerle J, Lerch MM
The Journal of biological chemistry293(3)1018-1029(2018 Jan)

Lysosomal processing of progranulin.
Zhou X, Paushter DH, Feng T, Sun L, Reinheckel T, Hu F
Molecular neurodegeneration12(1)62(2017 08)

Cathepsin D regulates lipid metabolism in murine steatohepatitis.
Houben T, Oligschlaeger Y, Hendrikx T, Bitorina AV, Walenbergh SMA, van Gorp PJ, Gijbels MJJ, Friedrichs S, Plat J, Schaap FG, L?tjohann D, Hofker MH, Shiri-Sverdlov R
Scientific reports7(1)3494(2017 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results suggested that Purkinje cells (PCs) were more vulnerable to CTSD deficiency in lysosomes than to autophagy impairment, and this vulnerability does not depend on the severity of axonal swelling.
Title: Purkinje Cells Are More Vulnerable to the Specific Depletion of Cathepsin D Than to That of Atg7.

Study demonstrate that PGRN interacts with the lysosomal protease CTSD and maintains its proper activity in vivo. Therefore, by regulating CTSD activity, PGRN may modulate protein homeostasis. This could potentially explain the TDP-43 aggregation observed in frontotemporal lobar degeneration with GRN mutations.
Title: Regulation of cathepsin D activity by the FTLD protein progranulin.

the cytosolic Cat D level and Cat D activity was significantly upregulated in response to oxygen-glucose deprivation/reperfusion exposure.
Title: Cathepsin D is involved in the oxygen and glucose deprivation/reperfusion-induced apoptosis of astrocytes.

these results suggest that inhibition of lysosomal proteases, such as CtsD, could be a new therapeutic approach to reduce renal fibrosis and slow progression of chronic kidney disease.
Title: Inhibition of lysosomal protease cathepsin D reduces renal fibrosis in murine chronic kidney disease.

Exposure of J774A.1 cells to HOCl or HOSCN resulted in a significant decrease in the activity of the Cys-dependent cathepsins B and L, but not the Asp-dependent cathepsin D.
Title: Role of Myeloperoxidase Oxidants in the Modulation of Cellular Lysosomal Enzyme Function: A Contributing Factor to Macrophage Dysfunction in Atherosclerosis?

The following Ctsd gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ctsd cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu18028	NM_009983.3 Latest version!	Mus musculus cathepsin D (Ctsd), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
View Old Accession Versions >>
OMu18028	NM_009983.2	Mus musculus cathepsin D (Ctsd), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ctsd ( NM_009983.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034113.1 Mus musculus cathepsin D (Ctsd), mRNA.

Price & Availability↑

CloneID	OMu18028
Clone ID Related Accession (Same CDS sequence)	NM_009983.3 , NM_009983.2
Accession Version	NM_009983.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1233bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-22
Organism	Mus musculus(house mouse)
Product	cathepsin D precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from X52886.1 and CD741449.1. On Jun 3, 2018 this sequence version replaced NM_009983.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC054758.1, X52886.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGACTC CCGGCGTCTT GCTGCTCATT CTCGGCCTCC TGGCTTCGTC CTCCTTCGCG 
ATTATCAGAA TCCCTCTGCG CAAGTTCACA TCTATCCGTC GGACTATGAC GGAGGTGGGC 
GGCTCTGTGG AAGACCTGAT CCTCAAAGGC CCCATCACCA AGTACTCCAT GCAGTCATCG 
CCTAAGACCA CGGAGCCAGT GTCAGAGTTA CTCAAAAACT ACCTGGATGC CCAGTACTAT 
GGCGATATCG GCATCGGAAC CCCGCCGCAG TGTTTCACAG TCGTCTTTGA TACTGGCTCC 
TCTAACCTGT GGGTCCCCTC CATTCATTGC AAGATACTTG ACATAGCCTG CTGGGTCCAC 
CATAAGTACA ACAGTGACAA GTCCAGCACC TATGTGAAGA ACGGCACGTC CTTTGACATC 
CACTACGGCT CAGGAAGCCT CTCTGGGTAC CTGAGCCAGG ACACTGTATC GGTTCCATGT 
AAGTCTGACC AGTCAAAGGC AAGAGGTATC AAGGTGGAGA AACAGATCTT TGGAGAAGCC 
ACCAAGCAGC CTGGAATCGT ATTTGTTGCA GCCAAGTTTG ATGGCATCTT GGGCATGGGC 
TACCCTCATA TCTCTGTTAA CAACGTGCTT CCGGTCTTTG ACAACCTGAT GCAACAGAAG 
CTGGTGGACA AGAACATCTT CTCCTTCTAC CTGAACAGGG ACCCAGAAGG GCAACCCGGA 
GGAGAACTAA TGCTTGGTGG CACTGACTCC AAGTACTACC ACGGGGAGCT GTCCTACCTG 
AACGTCACTC GAAAGGCCTA CTGGCAGGTG CACATGGACC AGTTGGAGGT GGGCAATGAG 
CTGACCCTGT GCAAGGGAGG CTGTGAGGCT ATTGTGGACA CAGGGACATC TCTTCTGGTG 
GGGCCTGTGG AAGAGGTGAA GGAGCTGCAG AAGGCCATCG GGGCAGTGCC TCTTATCCAG 
GGTGAGTATA TGATTCCTTG TGAGAAGGTG TCCAGCCTGC CCACGGTCTA CCTGAAGCTA 
GGAGGCAAAA ACTATGAACT ACACCCAGAC AAGTATATAC TCAAGGTATC GCAGGGTGGA 
AAGACAATCT GCCTGAGTGG CTTCATGGGA ATGGACATAC CCCCTCCCAG TGGGCCGCTC 
TGGATCCTGG GCGATGTCTT CATTGGTTCC TACTACACTG TGTTTGACAG AGACAACAAT 
AGGGTCGGCT TTGCCAATGC TGTCGTACTC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034113.1
CDS	24..1256
Translation	MKTPGVLLLILGLLASSSFAIIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPKTTEPVSELLKNYLDAQYYGDIGIGTPPQCFTVVFDTGSSNLWVPSIHCKILDIACWVHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDQSKARGIKVEKQIFGEATKQPGIVFVAAKFDGILGMGYPHISVNNVLPVFDNLMQQKLVDKNIFSFYLNRDPEGQPGGELMLGGTDSKYYHGELSYLNVTRKAYWQVHMDQLEVGNELTLCKGGCEAIVDTGTSLLVGPVEEVKELQKAIGAVPLIQGEYMIPCEKVSSLPTVYLKLGGKNYELHPDKYILKVSQGGKTICLSGFMGMDIPPPSGPLWILGDVFIGSYYTVFDRDNNRVGFANAVVL

Target ORF information:

RefSeq Version	NM_009983.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus cathepsin D (Ctsd), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009983.3

ORF Insert Sequence:

ATGAAGACTC CCGGCGTCTT GCTGCTCATT CTCGGCCTCC TGGCTTCGTC CTCCTTCGCG 
ATTATCAGAA TCCCTCTGCG CAAGTTCACA TCTATCCGTC GGACTATGAC GGAGGTGGGC 
GGCTCTGTGG AAGACCTGAT CCTCAAAGGC CCCATCACCA AGTACTCCAT GCAGTCATCG 
CCTAAGACCA CGGAGCCAGT GTCAGAGTTA CTCAAAAACT ACCTGGATGC CCAGTACTAT 
GGCGATATCG GCATCGGAAC CCCGCCGCAG TGTTTCACAG TCGTCTTTGA TACTGGCTCC 
TCTAACCTGT GGGTCCCCTC CATTCATTGC AAGATACTTG ACATAGCCTG CTGGGTCCAC 
CATAAGTACA ACAGTGACAA GTCCAGCACC TATGTGAAGA ACGGCACGTC CTTTGACATC 
CACTACGGCT CAGGAAGCCT CTCTGGGTAC CTGAGCCAGG ACACTGTATC GGTTCCATGT 
AAGTCTGACC AGTCAAAGGC AAGAGGTATC AAGGTGGAGA AACAGATCTT TGGAGAAGCC 
ACCAAGCAGC CTGGAATCGT ATTTGTTGCA GCCAAGTTTG ATGGCATCTT GGGCATGGGC 
TACCCTCATA TCTCTGTTAA CAACGTGCTT CCGGTCTTTG ACAACCTGAT GCAACAGAAG 
CTGGTGGACA AGAACATCTT CTCCTTCTAC CTGAACAGGG ACCCAGAAGG GCAACCCGGA 
GGAGAACTAA TGCTTGGTGG CACTGACTCC AAGTACTACC ACGGGGAGCT GTCCTACCTG 
AACGTCACTC GAAAGGCCTA CTGGCAGGTG CACATGGACC AGTTGGAGGT GGGCAATGAG 
CTGACCCTGT GCAAGGGAGG CTGTGAGGCT ATTGTGGACA CAGGGACATC TCTTCTGGTG 
GGGCCTGTGG AAGAGGTGAA GGAGCTGCAG AAGGCCATCG GGGCAGTGCC TCTTATCCAG 
GGTGAGTATA TGATTCCTTG TGAGAAGGTG TCCAGCCTGC CCACGGTCTA CCTGAAGCTA 
GGAGGCAAAA ACTATGAACT ACACCCAGAC AAGTATATAC TCAAGGTATC GCAGGGTGGA 
AAGACAATCT GCCTGAGTGG CTTCATGGGA ATGGACATAC CCCCTCCCAG TGGGCCGCTC 
TGGATCCTGG GCGATGTCTT CATTGGTTCC TACTACACTG TGTTTGACAG AGACAACAAT 
AGGGTCGGCT TTGCCAATGC TGTCGTACTC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ctsd ( NM_009983.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034113.1 Mus musculus cathepsin D (Ctsd), mRNA.

Price & Availability↑

CloneID	OMu18028
Clone ID Related Accession (Same CDS sequence)	NM_009983.3 , NM_009983.2
Accession Version	NM_009983.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1233bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Mus musculus(house mouse)
Product	cathepsin D precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X52886.1. On Jun 18, 2002 this sequence version replaced NM_009983.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X52886.1, BC054758.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGAAGACTC CCGGCGTCTT GCTGCTCATT CTCGGCCTCC TGGCTTCGTC CTCCTTCGCG 
ATTATCAGAA TCCCTCTGCG CAAGTTCACA TCTATCCGTC GGACTATGAC GGAGGTGGGC 
GGCTCTGTGG AAGACCTGAT CCTCAAAGGC CCCATCACCA AGTACTCCAT GCAGTCATCG 
CCTAAGACCA CGGAGCCAGT GTCAGAGTTA CTCAAAAACT ACCTGGATGC CCAGTACTAT 
GGCGATATCG GCATCGGAAC CCCGCCGCAG TGTTTCACAG TCGTCTTTGA TACTGGCTCC 
TCTAACCTGT GGGTCCCCTC CATTCATTGC AAGATACTTG ACATAGCCTG CTGGGTCCAC 
CATAAGTACA ACAGTGACAA GTCCAGCACC TATGTGAAGA ACGGCACGTC CTTTGACATC 
CACTACGGCT CAGGAAGCCT CTCTGGGTAC CTGAGCCAGG ACACTGTATC GGTTCCATGT 
AAGTCTGACC AGTCAAAGGC AAGAGGTATC AAGGTGGAGA AACAGATCTT TGGAGAAGCC 
ACCAAGCAGC CTGGAATCGT ATTTGTTGCA GCCAAGTTTG ATGGCATCTT GGGCATGGGC 
TACCCTCATA TCTCTGTTAA CAACGTGCTT CCGGTCTTTG ACAACCTGAT GCAACAGAAG 
CTGGTGGACA AGAACATCTT CTCCTTCTAC CTGAACAGGG ACCCAGAAGG GCAACCCGGA 
GGAGAACTAA TGCTTGGTGG CACTGACTCC AAGTACTACC ACGGGGAGCT GTCCTACCTG 
AACGTCACTC GAAAGGCCTA CTGGCAGGTG CACATGGACC AGTTGGAGGT GGGCAATGAG 
CTGACCCTGT GCAAGGGAGG CTGTGAGGCT ATTGTGGACA CAGGGACATC TCTTCTGGTG 
GGGCCTGTGG AAGAGGTGAA GGAGCTGCAG AAGGCCATCG GGGCAGTGCC TCTTATCCAG 
GGTGAGTATA TGATTCCTTG TGAGAAGGTG TCCAGCCTGC CCACGGTCTA CCTGAAGCTA 
GGAGGCAAAA ACTATGAACT ACACCCAGAC AAGTATATAC TCAAGGTATC GCAGGGTGGA 
AAGACAATCT GCCTGAGTGG CTTCATGGGA ATGGACATAC CCCCTCCCAG TGGGCCGCTC 
TGGATCCTGG GCGATGTCTT CATTGGTTCC TACTACACTG TGTTTGACAG AGACAACAAT 
AGGGTCGGCT TTGCCAATGC TGTCGTACTC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034113.1
CDS	67..1299
Translation	MKTPGVLLLILGLLASSSFAIIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPKTTEPVSELLKNYLDAQYYGDIGIGTPPQCFTVVFDTGSSNLWVPSIHCKILDIACWVHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDQSKARGIKVEKQIFGEATKQPGIVFVAAKFDGILGMGYPHISVNNVLPVFDNLMQQKLVDKNIFSFYLNRDPEGQPGGELMLGGTDSKYYHGELSYLNVTRKAYWQVHMDQLEVGNELTLCKGGCEAIVDTGTSLLVGPVEEVKELQKAIGAVPLIQGEYMIPCEKVSSLPTVYLKLGGKNYELHPDKYILKVSQGGKTICLSGFMGMDIPPPSGPLWILGDVFIGSYYTVFDRDNNRVGFANAVVL

Target ORF information:

RefSeq Version	NM_009983.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus cathepsin D (Ctsd), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009983.2

ORF Insert Sequence:

ATGAAGACTC CCGGCGTCTT GCTGCTCATT CTCGGCCTCC TGGCTTCGTC CTCCTTCGCG 
ATTATCAGAA TCCCTCTGCG CAAGTTCACA TCTATCCGTC GGACTATGAC GGAGGTGGGC 
GGCTCTGTGG AAGACCTGAT CCTCAAAGGC CCCATCACCA AGTACTCCAT GCAGTCATCG 
CCTAAGACCA CGGAGCCAGT GTCAGAGTTA CTCAAAAACT ACCTGGATGC CCAGTACTAT 
GGCGATATCG GCATCGGAAC CCCGCCGCAG TGTTTCACAG TCGTCTTTGA TACTGGCTCC 
TCTAACCTGT GGGTCCCCTC CATTCATTGC AAGATACTTG ACATAGCCTG CTGGGTCCAC 
CATAAGTACA ACAGTGACAA GTCCAGCACC TATGTGAAGA ACGGCACGTC CTTTGACATC 
CACTACGGCT CAGGAAGCCT CTCTGGGTAC CTGAGCCAGG ACACTGTATC GGTTCCATGT 
AAGTCTGACC AGTCAAAGGC AAGAGGTATC AAGGTGGAGA AACAGATCTT TGGAGAAGCC 
ACCAAGCAGC CTGGAATCGT ATTTGTTGCA GCCAAGTTTG ATGGCATCTT GGGCATGGGC 
TACCCTCATA TCTCTGTTAA CAACGTGCTT CCGGTCTTTG ACAACCTGAT GCAACAGAAG 
CTGGTGGACA AGAACATCTT CTCCTTCTAC CTGAACAGGG ACCCAGAAGG GCAACCCGGA 
GGAGAACTAA TGCTTGGTGG CACTGACTCC AAGTACTACC ACGGGGAGCT GTCCTACCTG 
AACGTCACTC GAAAGGCCTA CTGGCAGGTG CACATGGACC AGTTGGAGGT GGGCAATGAG 
CTGACCCTGT GCAAGGGAGG CTGTGAGGCT ATTGTGGACA CAGGGACATC TCTTCTGGTG 
GGGCCTGTGG AAGAGGTGAA GGAGCTGCAG AAGGCCATCG GGGCAGTGCC TCTTATCCAG 
GGTGAGTATA TGATTCCTTG TGAGAAGGTG TCCAGCCTGC CCACGGTCTA CCTGAAGCTA 
GGAGGCAAAA ACTATGAACT ACACCCAGAC AAGTATATAC TCAAGGTATC GCAGGGTGGA 
AAGACAATCT GCCTGAGTGG CTTCATGGGA ATGGACATAC CCCCTCCCAG TGGGCCGCTC 
TGGATCCTGG GCGATGTCTT CATTGGTTCC TACTACACTG TGTTTGACAG AGACAACAAT 
AGGGTCGGCT TTGCCAATGC TGTCGTACTC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cathepsin D regulates cathepsin B activation and disease severity predominantly in inflammatory cells during experimental pancreatitis.
The Journal of biological chemistry293(3)1018-1029(2018 Jan)
Aghdassi AA,John DS,Sendler M,Weiss FU,Reinheckel T,Mayerle J,Lerch MM

Lysosomal processing of progranulin.
Molecular neurodegeneration12(1)62(2017 08)
Zhou X,Paushter DH,Feng T,Sun L,Reinheckel T,Hu F

Cathepsin D regulates lipid metabolism in murine steatohepatitis.
Scientific reports7(1)3494(2017 Jun)
Houben T,Oligschlaeger Y,Hendrikx T,Bitorina AV,Walenbergh SMA,van Gorp PJ,Gijbels MJJ,Friedrichs S,Plat J,Schaap FG,L?tjohann D,Hofker MH,Shiri-Sverdlov R

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Ctsd cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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