Pnpla3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pnpla3
Entrez Gene ID	116939
Full Name	patatin-like phospholipase domain containing 3
Synonyms	Adpn
General protein information	Preferred Names patatin-like phospholipase domain containing 3 Names patatin-like phospholipase domain-containing protein 3 acylglycerol O-acyltransferase adiponutrin calcium-independent phospholipase A2-epsilon iPLA2-epsilon
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15\|15 E2

mRNA and Protein(s)

mRNA	Protein	Name
NM_054088.3	NP_473429.2	1-acylglycerol-3-phosphate O-acyltransferase Pnpla3
XM_006520346.4	XP_006520409.1	1-acylglycerol-3-phosphate O-acyltransferase Pnpla3 isoform X2
XM_006520345.3	XP_006520408.1	patatin-like phospholipase domain-containing protein 3 isoform X1
XM_006520345.4	XP_006520408.1	1-acylglycerol-3-phosphate O-acyltransferase Pnpla3 isoform X1
XM_006520346.3	XP_006520409.1	patatin-like phospholipase domain-containing protein 3 isoform X2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PNPLA3	XP_515184.3
Bos taurus (cattle)	LOC786474	XP_005207516.1
	PNPLA3	XP_001109144.1
Canis lupus familiaris (dog)	PNPLA3	XP_005625821.1
Bos taurus (cattle)	PNPLA3	XP_002688020.2
Homo sapiens (human)	PNPLA3	NP_079501.2
Mus musculus (house mouse)	Pnpla3	NP_473429.2
Rattus norvegicus (Norway rat)	Pnpla3	NP_001269253.1

Gene Ontology
Bibliography

Related articles in PubMed

The PNPLA3 variant associated with fatty liver disease (I148M) accumulates on lipid droplets by evading ubiquitylation.
BasuRay S, Smagris E, Cohen JC, Hobbs HH
Hepatology (Baltimore, Md.)66(4)1111-1124(2017 10)

Binge alcohol alters PNPLA3 levels in liver through epigenetic mechanism involving histone H3 acetylation.
Restrepo RJ, Lim RW, Korthuis RJ, Shukla SD
Alcohol (Fayetteville, N.Y.)6077-82(2017 May)

Activation of the Constitutive Androstane Receptor induces hepatic lipogenesis and regulates Pnpla3 gene expression in a LXR-independent way.
Marmugi A, Lukowicz C, Lasserre F, Montagner A, Polizzi A, Ducheix S, Goron A, Gamet-Payrastre L, Gerbal-Chaloin S, Pascussi JM, Moldes M, Pineau T, Guillou H, Mselli-Lakhal L
Toxicology and applied pharmacology30390-100(2016 07)

Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis.
Smagris E, BasuRay S, Li J, Huang Y, Lai KM, Gromada J, Cohen JC, Hobbs HH
Hepatology (Baltimore, Md.)61(1)108-18(2015 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

148M variant disrupts ubiquitylation and proteasomal degradation
Title: The PNPLA3 variant associated with fatty liver disease (I148M) accumulates on lipid droplets by evading ubiquitylation.

Neither ablation nor overexpression of wild-type PNPLA3 affects liver fat content in mice, whereas hepatic overexpression of the human 148M transgene causes steatosis.
Title: Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis.

rs738409 exerts a marked influence on hepatocarcinogenesis in patients with cirrhosis of European descent.
Title: Association between the PNPLA3 (rs738409 C>G) variant and hepatocellular carcinoma: Evidence from a meta-analysis of individual participant data.

PNPLA3 plays a role in remodeling TAG in lipid droplets, as they accumulate in response to food intake
Title: Chronic overexpression of PNPLA3I148M in mouse liver causes hepatic steatosis.

adiponutrin/PNPLA3 is regulated by two key factors of the glycolytic and lipogenic pathways, raising the question of its implication in the metabolism of carbohydrates and lipids
Title: Distinct regulation of adiponutrin/PNPLA3 gene expression by the transcription factors ChREBP and SREBP1c in mouse and human hepatocytes.

The following Pnpla3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pnpla3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu09572	NM_054088.3 Latest version!	Mus musculus patatin-like phospholipase domain containing 3 (Pnpla3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu50880	XM_006520345.4 Latest version!	Mus musculus patatin-like phospholipase domain containing 3 (Pnpla3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu50881	XM_006520346.4 Latest version!	Mus musculus patatin-like phospholipase domain containing 3 (Pnpla3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OMu50880	XM_006520345.3	Mus musculus patatin-like phospholipase domain containing 3 (Pnpla3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu50881	XM_006520346.3	Mus musculus patatin-like phospholipase domain containing 3 (Pnpla3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pnpla3 ( NM_054088.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_473429.2 Mus musculus patatin-like phospholipase domain containing 3 (Pnpla3), mRNA.

Price & Availability↑

CloneID	OMu09572
Clone ID Related Accession (Same CDS sequence)	NM_054088.3
Accession Version	NM_054088.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1155bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Mus musculus(house mouse)
Product	1-acylglycerol-3-phosphate O-acyltransferase Pnpla3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY277293.1, BC028792.1 and AL626769.18. On Apr 7, 2007 this sequence version replaced NM_054088.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY037763.1, BC028792.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGTATGACC CAGAGCGCCG CTGGAGCCTG TCGTTTGCAG GCTGCGGCTT CCTGGGCTTC 
TACCACGTCG GGGCTACGCT ATGTCTGAGC GAGCGCGCCC CGCACCTCCT CCGCGATGCG 
CGCACTTTCT TTGGCTGCTC GGCCGGTGCA CTGCACGCGG TCACCTTCGT GTGCAGTCTC 
CCTCTCGGCC GTATAATGGA GATCCTCATG GACCTCGTGC GGAAAGCCAG GAGCCGCAAC 
ATCGGCACCC TCCACCCGTT CTTCAACATT AACAAGTGCA TCAGAGACGG GCTCCAGGAG 
AGCCTCCCAG ACAATGTCCA CCAGGTCATT TCTGGCAAGG TTCACATCTC ACTCACCAGG 
GTGTCGGATG GGGAGAACGT GCTGGTGTCT GAGTTCCATT CCAAAGACGA AGTCGTGGAT 
GCCCTGGTGT GTTCCTGCTT CATTCCCCTC TTCTCTGGCC TAATCCCTCC TTCCTTCCGA 
GGCGAGCGGT ACGTGGACGG AGGAGTGAGC GACAACGTCC CTGTGCTGGA TGCCAAAACC 
ACCATCACGG TGTCACCTTT CTACGGTGAG CATGACATCT GCCCCAAAGT CAAGTCCACC 
AACTTCTTCC ACGTGAATAT CACCAACCTC AGCCTCCGCC TCTGCACTGG GAACCTCCAA 
CTTCTGACCA GAGCGCTCTT CCCGTCTGAT GTGAAGGTGA TGGGAGAGCT GTGCTATCAA 
GGGTACCTGG ACGCCTTCCG GTTCCTGGAG GAGAATGGCA TCTGTAACGG GCCACAGCGC 
AGCCTGAGTC TGTCCTTGGT GGCGCCAGAA GCCTGCTTGG AAAATGGCAA ACTTGTGGGA 
GACAAGGTGC CAGTCAGCCT ATGCTTTACA GATGAGAACA TCTGGGAGAC ACTGTCCCCC 
GAGCTCAGCA CAGCTCTGAG TGAAGCGATT AAGGACAGGG AGGGCTACCT GAGCAAAGTC 
TGCAACCTCC TGCCCGTCAG GATCCTGTCC TACATCATGC TGCCCTGCAG TCTGCCCGTG 
GAGTCGGCTA TCGCTGCAGT CCACAGGCTG GTGACATGGC TCCCTGATAT CCAGGATGAT 
ATCCAGTGGC TACAATGGGC GACATCCCAG GTTTGTGCCC GAATGACGAT GTGCCTGCTC 
CCCTCTACCA GGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_473429.2
CDS	59..1213
Translation	MYDPERRWSLSFAGCGFLGFYHVGATLCLSERAPHLLRDARTFFGCSAGALHAVTFVCSLPLGRIMEILMDLVRKARSRNIGTLHPFFNINKCIRDGLQESLPDNVHQVISGKVHISLTRVSDGENVLVSEFHSKDEVVDALVCSCFIPLFSGLIPPSFRGERYVDGGVSDNVPVLDAKTTITVSPFYGEHDICPKVKSTNFFHVNITNLSLRLCTGNLQLLTRALFPSDVKVMGELCYQGYLDAFRFLEENGICNGPQRSLSLSLVAPEACLENGKLVGDKVPVSLCFTDENIWETLSPELSTALSEAIKDREGYLSKVCNLLPVRILSYIMLPCSLPVESAIAAVHRLVTWLPDIQDDIQWLQWATSQVCARMTMCLLPSTR

Target ORF information:

RefSeq Version	NM_054088.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus patatin-like phospholipase domain containing 3 (Pnpla3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_054088.3

ORF Insert Sequence:

ATGTATGACC CAGAGCGCCG CTGGAGCCTG TCGTTTGCAG GCTGCGGCTT CCTGGGCTTC 
TACCACGTCG GGGCTACGCT ATGTCTGAGC GAGCGCGCCC CGCACCTCCT CCGCGATGCG 
CGCACTTTCT TTGGCTGCTC GGCCGGTGCA CTGCACGCGG TCACCTTCGT GTGCAGTCTC 
CCTCTCGGCC GTATAATGGA GATCCTCATG GACCTCGTGC GGAAAGCCAG GAGCCGCAAC 
ATCGGCACCC TCCACCCGTT CTTCAACATT AACAAGTGCA TCAGAGACGG GCTCCAGGAG 
AGCCTCCCAG ACAATGTCCA CCAGGTCATT TCTGGCAAGG TTCACATCTC ACTCACCAGG 
GTGTCGGATG GGGAGAACGT GCTGGTGTCT GAGTTCCATT CCAAAGACGA AGTCGTGGAT 
GCCCTGGTGT GTTCCTGCTT CATTCCCCTC TTCTCTGGCC TAATCCCTCC TTCCTTCCGA 
GGCGAGCGGT ACGTGGACGG AGGAGTGAGC GACAACGTCC CTGTGCTGGA TGCCAAAACC 
ACCATCACGG TGTCACCTTT CTACGGTGAG CATGACATCT GCCCCAAAGT CAAGTCCACC 
AACTTCTTCC ACGTGAATAT CACCAACCTC AGCCTCCGCC TCTGCACTGG GAACCTCCAA 
CTTCTGACCA GAGCGCTCTT CCCGTCTGAT GTGAAGGTGA TGGGAGAGCT GTGCTATCAA 
GGGTACCTGG ACGCCTTCCG GTTCCTGGAG GAGAATGGCA TCTGTAACGG GCCACAGCGC 
AGCCTGAGTC TGTCCTTGGT GGCGCCAGAA GCCTGCTTGG AAAATGGCAA ACTTGTGGGA 
GACAAGGTGC CAGTCAGCCT ATGCTTTACA GATGAGAACA TCTGGGAGAC ACTGTCCCCC 
GAGCTCAGCA CAGCTCTGAG TGAAGCGATT AAGGACAGGG AGGGCTACCT GAGCAAAGTC 
TGCAACCTCC TGCCCGTCAG GATCCTGTCC TACATCATGC TGCCCTGCAG TCTGCCCGTG 
GAGTCGGCTA TCGCTGCAGT CCACAGGCTG GTGACATGGC TCCCTGATAT CCAGGATGAT 
ATCCAGTGGC TACAATGGGC GACATCCCAG GTTTGTGCCC GAATGACGAT GTGCCTGCTC 
CCCTCTACCA GGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pnpla3 ( XM_006520345.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006520408.1 Mus musculus patatin-like phospholipase domain containing 3 (Pnpla3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu50880
Clone ID Related Accession (Same CDS sequence)	XM_006520345.3 , XM_006520345.4
Accession Version	XM_006520345.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1299bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	patatin-like phospholipase domain-containing protein 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006520345.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTATGACC CAGAGCGCCG CTGGAGCCTG TCGTTTGCAG GCTGCGGCTT CCTGGGCTTC 
TACCACGTCG GGGCTACGCT ATGTCTGAGC GAGCGCGCCC CGCACCTCCT CCGCGATGCG 
CGCACTTTCT TTGGCTGCTC GGCCGGTGCA CTGCACGCGG TCACCTTCGT GTGCAGTCTC 
CCTCTCGGCC GTATAATGGA GATCCTCATG GACCTCGTGC GGAAAGCCAG GAGCCGCAAC 
ATCGGCACCC TCCACCCGTT CTTCAACATT AACAAGTGCA TCAGAGACGG GCTCCAGGAG 
AGCCTCCCAG ACAATGTCCA CCAGGTCATT TCTGGCAAGG TTCACATCTC ACTCACCAGG 
GTGTCGGATG GGGAGAACGT GCTGGTGTCT GAGTTCCATT CCAAAGACGA AGTCGTGGAT 
GCCCTGGTGT GTTCCTGCTT CATTCCCCTC TTCTCTGGCC TAATCCCTCC TTCCTTCCGA 
GGCGAGCGGT ACGTGGACGG AGGAGTGAGC GACAACGTCC CTGTGCTGGA TGCCAAAACC 
ACCATCACGG TGTCACCTTT CTACGGTGAG CATGACATCT GCCCCAAAGT CAAGTCCACC 
AACTTCTTCC ACGTGAATAT CACCAACCTC AGCCTCCGCC TCTGCACTGG GAACCTCCAA 
CTTCTGACCA GAGCGCTCTT CCCGTCTGAT GTGAAGGTGA TGGGAGAGCT GTGCTATCAA 
GGGTACCTGG ACGCCTTCCG GTTCCTGGAG GAGAATGGCA TCTGTAACGG GCCACAGCGC 
AGCCTGAGTC TGTCCTTGGT GGCGCCAGAA GCCTGCTTGG AAAATGGCAA ACTTGTGGGA 
GACAAGGTGC CAGTCAGCCT ATGCTTTACA GATGAGAACA TCTGGGAGAC ACTGTCCCCC 
GAGCTCAGCA CAGCTCTGAG TGAAGCGATT AAGGACAGGG AGGGCTACCT GAGCAAAGTC 
TGCAACCTCC TGCCCGTCAG GATCCTGTCC TACATCATGC TGCCCTGCAG TCTGCCCGTG 
GAGTCGGCTA TCGCTGCAGT CCACAGGCTG GTGACATGGC TCCCTGATAT CCAGGATGAT 
ATCCAGTGGC TACAATGGGC GACATCCCAG GTTTGTGCCC GAATGACGAT GTGCCTGCTC 
CCCTCTACCA GCATGAGATT CCTGGGACAA TCCCAATTCC TTGGCCTCCA TTGTATCAAA 
GGGCTGAAAA CCAAAGGGAA GGCACAGCTG TCTCTTCAGC ATGCCTCTTC TGCCAGAACC 
ACTGCAAGGT TTGGTGCTCA GGCTGTGCAA ACATTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006520408.1
CDS	91..1389
Translation	MYDPERRWSLSFAGCGFLGFYHVGATLCLSERAPHLLRDARTFFGCSAGALHAVTFVCSLPLGRIMEILMDLVRKARSRNIGTLHPFFNINKCIRDGLQESLPDNVHQVISGKVHISLTRVSDGENVLVSEFHSKDEVVDALVCSCFIPLFSGLIPPSFRGERYVDGGVSDNVPVLDAKTTITVSPFYGEHDICPKVKSTNFFHVNITNLSLRLCTGNLQLLTRALFPSDVKVMGELCYQGYLDAFRFLEENGICNGPQRSLSLSLVAPEACLENGKLVGDKVPVSLCFTDENIWETLSPELSTALSEAIKDREGYLSKVCNLLPVRILSYIMLPCSLPVESAIAAVHRLVTWLPDIQDDIQWLQWATSQVCARMTMCLLPSTSMRFLGQSQFLGLHCIKGLKTKGKAQLSLQHASSARTTARFGAQAVQTF

Target ORF information:

RefSeq Version	XM_006520345.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus patatin-like phospholipase domain containing 3 (Pnpla3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006520345.3

ORF Insert Sequence:

ATGTATGACC CAGAGCGCCG CTGGAGCCTG TCGTTTGCAG GCTGCGGCTT CCTGGGCTTC 
TACCACGTCG GGGCTACGCT ATGTCTGAGC GAGCGCGCCC CGCACCTCCT CCGCGATGCG 
CGCACTTTCT TTGGCTGCTC GGCCGGTGCA CTGCACGCGG TCACCTTCGT GTGCAGTCTC 
CCTCTCGGCC GTATAATGGA GATCCTCATG GACCTCGTGC GGAAAGCCAG GAGCCGCAAC 
ATCGGCACCC TCCACCCGTT CTTCAACATT AACAAGTGCA TCAGAGACGG GCTCCAGGAG 
AGCCTCCCAG ACAATGTCCA CCAGGTCATT TCTGGCAAGG TTCACATCTC ACTCACCAGG 
GTGTCGGATG GGGAGAACGT GCTGGTGTCT GAGTTCCATT CCAAAGACGA AGTCGTGGAT 
GCCCTGGTGT GTTCCTGCTT CATTCCCCTC TTCTCTGGCC TAATCCCTCC TTCCTTCCGA 
GGCGAGCGGT ACGTGGACGG AGGAGTGAGC GACAACGTCC CTGTGCTGGA TGCCAAAACC 
ACCATCACGG TGTCACCTTT CTACGGTGAG CATGACATCT GCCCCAAAGT CAAGTCCACC 
AACTTCTTCC ACGTGAATAT CACCAACCTC AGCCTCCGCC TCTGCACTGG GAACCTCCAA 
CTTCTGACCA GAGCGCTCTT CCCGTCTGAT GTGAAGGTGA TGGGAGAGCT GTGCTATCAA 
GGGTACCTGG ACGCCTTCCG GTTCCTGGAG GAGAATGGCA TCTGTAACGG GCCACAGCGC 
AGCCTGAGTC TGTCCTTGGT GGCGCCAGAA GCCTGCTTGG AAAATGGCAA ACTTGTGGGA 
GACAAGGTGC CAGTCAGCCT ATGCTTTACA GATGAGAACA TCTGGGAGAC ACTGTCCCCC 
GAGCTCAGCA CAGCTCTGAG TGAAGCGATT AAGGACAGGG AGGGCTACCT GAGCAAAGTC 
TGCAACCTCC TGCCCGTCAG GATCCTGTCC TACATCATGC TGCCCTGCAG TCTGCCCGTG 
GAGTCGGCTA TCGCTGCAGT CCACAGGCTG GTGACATGGC TCCCTGATAT CCAGGATGAT 
ATCCAGTGGC TACAATGGGC GACATCCCAG GTTTGTGCCC GAATGACGAT GTGCCTGCTC 
CCCTCTACCA GCATGAGATT CCTGGGACAA TCCCAATTCC TTGGCCTCCA TTGTATCAAA 
GGGCTGAAAA CCAAAGGGAA GGCACAGCTG TCTCTTCAGC ATGCCTCTTC TGCCAGAACC 
ACTGCAAGGT TTGGTGCTCA GGCTGTGCAA ACATTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pnpla3 ( XM_006520346.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006520409.1 Mus musculus patatin-like phospholipase domain containing 3 (Pnpla3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu50881
Clone ID Related Accession (Same CDS sequence)	XM_006520346.4 , XM_006520346.3
Accession Version	XM_006520346.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1104bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	patatin-like phospholipase domain-containing protein 3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006520346.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGATCC TCATGGACCT CGTGCGGAAA GCCAGGAGCC GCAACATCGG CACCCTCCAC 
CCGTTCTTCA ACATTAACAA GTGCATCAGA GACGGGCTCC AGGAGAGCCT CCCAGACAAT 
GTCCACCAGG TCATTTCTGG CAAGGTTCAC ATCTCACTCA CCAGGGTGTC GGATGGGGAG 
AACGTGCTGG TGTCTGAGTT CCATTCCAAA GACGAAGTCG TGGATGCCCT GGTGTGTTCC 
TGCTTCATTC CCCTCTTCTC TGGCCTAATC CCTCCTTCCT TCCGAGGCGA GCGGTACGTG 
GACGGAGGAG TGAGCGACAA CGTCCCTGTG CTGGATGCCA AAACCACCAT CACGGTGTCA 
CCTTTCTACG GTGAGCATGA CATCTGCCCC AAAGTCAAGT CCACCAACTT CTTCCACGTG 
AATATCACCA ACCTCAGCCT CCGCCTCTGC ACTGGGAACC TCCAACTTCT GACCAGAGCG 
CTCTTCCCGT CTGATGTGAA GGTGATGGGA GAGCTGTGCT ATCAAGGGTA CCTGGACGCC 
TTCCGGTTCC TGGAGGAGAA TGGCATCTGT AACGGGCCAC AGCGCAGCCT GAGTCTGTCC 
TTGGTGGCGC CAGAAGCCTG CTTGGAAAAT GGCAAACTTG TGGGAGACAA GGTGCCAGTC 
AGCCTATGCT TTACAGATGA GAACATCTGG GAGACACTGT CCCCCGAGCT CAGCACAGCT 
CTGAGTGAAG CGATTAAGGA CAGGGAGGGC TACCTGAGCA AAGTCTGCAA CCTCCTGCCC 
GTCAGGATCC TGTCCTACAT CATGCTGCCC TGCAGTCTGC CCGTGGAGTC GGCTATCGCT 
GCAGTCCACA GGCTGGTGAC ATGGCTCCCT GATATCCAGG ATGATATCCA GTGGCTACAA 
TGGGCGACAT CCCAGGTTTG TGCCCGAATG ACGATGTGCC TGCTCCCCTC TACCAGCATG 
AGATTCCTGG GACAATCCCA ATTCCTTGGC CTCCATTGTA TCAAAGGGCT GAAAACCAAA 
GGGAAGGCAC AGCTGTCTCT TCAGCATGCC TCTTCTGCCA GAACCACTGC AAGGTTTGGT 
GCTCAGGCTG TGCAAACATT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006520409.1
CDS	318..1421
Translation	MEILMDLVRKARSRNIGTLHPFFNINKCIRDGLQESLPDNVHQVISGKVHISLTRVSDGENVLVSEFHSKDEVVDALVCSCFIPLFSGLIPPSFRGERYVDGGVSDNVPVLDAKTTITVSPFYGEHDICPKVKSTNFFHVNITNLSLRLCTGNLQLLTRALFPSDVKVMGELCYQGYLDAFRFLEENGICNGPQRSLSLSLVAPEACLENGKLVGDKVPVSLCFTDENIWETLSPELSTALSEAIKDREGYLSKVCNLLPVRILSYIMLPCSLPVESAIAAVHRLVTWLPDIQDDIQWLQWATSQVCARMTMCLLPSTSMRFLGQSQFLGLHCIKGLKTKGKAQLSLQHASSARTTARFGAQAVQTF

Target ORF information:

RefSeq Version	XM_006520346.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus patatin-like phospholipase domain containing 3 (Pnpla3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006520346.3

ORF Insert Sequence:

ATGGAGATCC TCATGGACCT CGTGCGGAAA GCCAGGAGCC GCAACATCGG CACCCTCCAC 
CCGTTCTTCA ACATTAACAA GTGCATCAGA GACGGGCTCC AGGAGAGCCT CCCAGACAAT 
GTCCACCAGG TCATTTCTGG CAAGGTTCAC ATCTCACTCA CCAGGGTGTC GGATGGGGAG 
AACGTGCTGG TGTCTGAGTT CCATTCCAAA GACGAAGTCG TGGATGCCCT GGTGTGTTCC 
TGCTTCATTC CCCTCTTCTC TGGCCTAATC CCTCCTTCCT TCCGAGGCGA GCGGTACGTG 
GACGGAGGAG TGAGCGACAA CGTCCCTGTG CTGGATGCCA AAACCACCAT CACGGTGTCA 
CCTTTCTACG GTGAGCATGA CATCTGCCCC AAAGTCAAGT CCACCAACTT CTTCCACGTG 
AATATCACCA ACCTCAGCCT CCGCCTCTGC ACTGGGAACC TCCAACTTCT GACCAGAGCG 
CTCTTCCCGT CTGATGTGAA GGTGATGGGA GAGCTGTGCT ATCAAGGGTA CCTGGACGCC 
TTCCGGTTCC TGGAGGAGAA TGGCATCTGT AACGGGCCAC AGCGCAGCCT GAGTCTGTCC 
TTGGTGGCGC CAGAAGCCTG CTTGGAAAAT GGCAAACTTG TGGGAGACAA GGTGCCAGTC 
AGCCTATGCT TTACAGATGA GAACATCTGG GAGACACTGT CCCCCGAGCT CAGCACAGCT 
CTGAGTGAAG CGATTAAGGA CAGGGAGGGC TACCTGAGCA AAGTCTGCAA CCTCCTGCCC 
GTCAGGATCC TGTCCTACAT CATGCTGCCC TGCAGTCTGC CCGTGGAGTC GGCTATCGCT 
GCAGTCCACA GGCTGGTGAC ATGGCTCCCT GATATCCAGG ATGATATCCA GTGGCTACAA 
TGGGCGACAT CCCAGGTTTG TGCCCGAATG ACGATGTGCC TGCTCCCCTC TACCAGCATG 
AGATTCCTGG GACAATCCCA ATTCCTTGGC CTCCATTGTA TCAAAGGGCT GAAAACCAAA 
GGGAAGGCAC AGCTGTCTCT TCAGCATGCC TCTTCTGCCA GAACCACTGC AAGGTTTGGT 
GCTCAGGCTG TGCAAACATT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pnpla3 ( XM_006520345.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006520408.1 Mus musculus patatin-like phospholipase domain containing 3 (Pnpla3), transcript variant X1, mRNA.

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CloneID	OMu50880
Clone ID Related Accession (Same CDS sequence)	XM_006520345.3 , XM_006520345.4
Accession Version	XM_006520345.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1299bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	1-acylglycerol-3-phosphate O-acyltransferase Pnpla3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006520345.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTATGACC CAGAGCGCCG CTGGAGCCTG TCGTTTGCAG GCTGCGGCTT CCTGGGCTTC 
TACCACGTCG GGGCTACGCT ATGTCTGAGC GAGCGCGCCC CGCACCTCCT CCGCGATGCG 
CGCACTTTCT TTGGCTGCTC GGCCGGTGCA CTGCACGCGG TCACCTTCGT GTGCAGTCTC 
CCTCTCGGCC GTATAATGGA GATCCTCATG GACCTCGTGC GGAAAGCCAG GAGCCGCAAC 
ATCGGCACCC TCCACCCGTT CTTCAACATT AACAAGTGCA TCAGAGACGG GCTCCAGGAG 
AGCCTCCCAG ACAATGTCCA CCAGGTCATT TCTGGCAAGG TTCACATCTC ACTCACCAGG 
GTGTCGGATG GGGAGAACGT GCTGGTGTCT GAGTTCCATT CCAAAGACGA AGTCGTGGAT 
GCCCTGGTGT GTTCCTGCTT CATTCCCCTC TTCTCTGGCC TAATCCCTCC TTCCTTCCGA 
GGCGAGCGGT ACGTGGACGG AGGAGTGAGC GACAACGTCC CTGTGCTGGA TGCCAAAACC 
ACCATCACGG TGTCACCTTT CTACGGTGAG CATGACATCT GCCCCAAAGT CAAGTCCACC 
AACTTCTTCC ACGTGAATAT CACCAACCTC AGCCTCCGCC TCTGCACTGG GAACCTCCAA 
CTTCTGACCA GAGCGCTCTT CCCGTCTGAT GTGAAGGTGA TGGGAGAGCT GTGCTATCAA 
GGGTACCTGG ACGCCTTCCG GTTCCTGGAG GAGAATGGCA TCTGTAACGG GCCACAGCGC 
AGCCTGAGTC TGTCCTTGGT GGCGCCAGAA GCCTGCTTGG AAAATGGCAA ACTTGTGGGA 
GACAAGGTGC CAGTCAGCCT ATGCTTTACA GATGAGAACA TCTGGGAGAC ACTGTCCCCC 
GAGCTCAGCA CAGCTCTGAG TGAAGCGATT AAGGACAGGG AGGGCTACCT GAGCAAAGTC 
TGCAACCTCC TGCCCGTCAG GATCCTGTCC TACATCATGC TGCCCTGCAG TCTGCCCGTG 
GAGTCGGCTA TCGCTGCAGT CCACAGGCTG GTGACATGGC TCCCTGATAT CCAGGATGAT 
ATCCAGTGGC TACAATGGGC GACATCCCAG GTTTGTGCCC GAATGACGAT GTGCCTGCTC 
CCCTCTACCA GCATGAGATT CCTGGGACAA TCCCAATTCC TTGGCCTCCA TTGTATCAAA 
GGGCTGAAAA CCAAAGGGAA GGCACAGCTG TCTCTTCAGC ATGCCTCTTC TGCCAGAACC 
ACTGCAAGGT TTGGTGCTCA GGCTGTGCAA ACATTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006520408.1
CDS	99..1397
Translation	MYDPERRWSLSFAGCGFLGFYHVGATLCLSERAPHLLRDARTFFGCSAGALHAVTFVCSLPLGRIMEILMDLVRKARSRNIGTLHPFFNINKCIRDGLQESLPDNVHQVISGKVHISLTRVSDGENVLVSEFHSKDEVVDALVCSCFIPLFSGLIPPSFRGERYVDGGVSDNVPVLDAKTTITVSPFYGEHDICPKVKSTNFFHVNITNLSLRLCTGNLQLLTRALFPSDVKVMGELCYQGYLDAFRFLEENGICNGPQRSLSLSLVAPEACLENGKLVGDKVPVSLCFTDENIWETLSPELSTALSEAIKDREGYLSKVCNLLPVRILSYIMLPCSLPVESAIAAVHRLVTWLPDIQDDIQWLQWATSQVCARMTMCLLPSTSMRFLGQSQFLGLHCIKGLKTKGKAQLSLQHASSARTTARFGAQAVQTF

Target ORF information:

RefSeq Version	XM_006520345.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus patatin-like phospholipase domain containing 3 (Pnpla3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006520345.4

ORF Insert Sequence:

ATGTATGACC CAGAGCGCCG CTGGAGCCTG TCGTTTGCAG GCTGCGGCTT CCTGGGCTTC 
TACCACGTCG GGGCTACGCT ATGTCTGAGC GAGCGCGCCC CGCACCTCCT CCGCGATGCG 
CGCACTTTCT TTGGCTGCTC GGCCGGTGCA CTGCACGCGG TCACCTTCGT GTGCAGTCTC 
CCTCTCGGCC GTATAATGGA GATCCTCATG GACCTCGTGC GGAAAGCCAG GAGCCGCAAC 
ATCGGCACCC TCCACCCGTT CTTCAACATT AACAAGTGCA TCAGAGACGG GCTCCAGGAG 
AGCCTCCCAG ACAATGTCCA CCAGGTCATT TCTGGCAAGG TTCACATCTC ACTCACCAGG 
GTGTCGGATG GGGAGAACGT GCTGGTGTCT GAGTTCCATT CCAAAGACGA AGTCGTGGAT 
GCCCTGGTGT GTTCCTGCTT CATTCCCCTC TTCTCTGGCC TAATCCCTCC TTCCTTCCGA 
GGCGAGCGGT ACGTGGACGG AGGAGTGAGC GACAACGTCC CTGTGCTGGA TGCCAAAACC 
ACCATCACGG TGTCACCTTT CTACGGTGAG CATGACATCT GCCCCAAAGT CAAGTCCACC 
AACTTCTTCC ACGTGAATAT CACCAACCTC AGCCTCCGCC TCTGCACTGG GAACCTCCAA 
CTTCTGACCA GAGCGCTCTT CCCGTCTGAT GTGAAGGTGA TGGGAGAGCT GTGCTATCAA 
GGGTACCTGG ACGCCTTCCG GTTCCTGGAG GAGAATGGCA TCTGTAACGG GCCACAGCGC 
AGCCTGAGTC TGTCCTTGGT GGCGCCAGAA GCCTGCTTGG AAAATGGCAA ACTTGTGGGA 
GACAAGGTGC CAGTCAGCCT ATGCTTTACA GATGAGAACA TCTGGGAGAC ACTGTCCCCC 
GAGCTCAGCA CAGCTCTGAG TGAAGCGATT AAGGACAGGG AGGGCTACCT GAGCAAAGTC 
TGCAACCTCC TGCCCGTCAG GATCCTGTCC TACATCATGC TGCCCTGCAG TCTGCCCGTG 
GAGTCGGCTA TCGCTGCAGT CCACAGGCTG GTGACATGGC TCCCTGATAT CCAGGATGAT 
ATCCAGTGGC TACAATGGGC GACATCCCAG GTTTGTGCCC GAATGACGAT GTGCCTGCTC 
CCCTCTACCA GCATGAGATT CCTGGGACAA TCCCAATTCC TTGGCCTCCA TTGTATCAAA 
GGGCTGAAAA CCAAAGGGAA GGCACAGCTG TCTCTTCAGC ATGCCTCTTC TGCCAGAACC 
ACTGCAAGGT TTGGTGCTCA GGCTGTGCAA ACATTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pnpla3 ( XM_006520346.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006520409.1 Mus musculus patatin-like phospholipase domain containing 3 (Pnpla3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu50881
Clone ID Related Accession (Same CDS sequence)	XM_006520346.4 , XM_006520346.3
Accession Version	XM_006520346.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1104bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	1-acylglycerol-3-phosphate O-acyltransferase Pnpla3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006520346.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGATCC TCATGGACCT CGTGCGGAAA GCCAGGAGCC GCAACATCGG CACCCTCCAC 
CCGTTCTTCA ACATTAACAA GTGCATCAGA GACGGGCTCC AGGAGAGCCT CCCAGACAAT 
GTCCACCAGG TCATTTCTGG CAAGGTTCAC ATCTCACTCA CCAGGGTGTC GGATGGGGAG 
AACGTGCTGG TGTCTGAGTT CCATTCCAAA GACGAAGTCG TGGATGCCCT GGTGTGTTCC 
TGCTTCATTC CCCTCTTCTC TGGCCTAATC CCTCCTTCCT TCCGAGGCGA GCGGTACGTG 
GACGGAGGAG TGAGCGACAA CGTCCCTGTG CTGGATGCCA AAACCACCAT CACGGTGTCA 
CCTTTCTACG GTGAGCATGA CATCTGCCCC AAAGTCAAGT CCACCAACTT CTTCCACGTG 
AATATCACCA ACCTCAGCCT CCGCCTCTGC ACTGGGAACC TCCAACTTCT GACCAGAGCG 
CTCTTCCCGT CTGATGTGAA GGTGATGGGA GAGCTGTGCT ATCAAGGGTA CCTGGACGCC 
TTCCGGTTCC TGGAGGAGAA TGGCATCTGT AACGGGCCAC AGCGCAGCCT GAGTCTGTCC 
TTGGTGGCGC CAGAAGCCTG CTTGGAAAAT GGCAAACTTG TGGGAGACAA GGTGCCAGTC 
AGCCTATGCT TTACAGATGA GAACATCTGG GAGACACTGT CCCCCGAGCT CAGCACAGCT 
CTGAGTGAAG CGATTAAGGA CAGGGAGGGC TACCTGAGCA AAGTCTGCAA CCTCCTGCCC 
GTCAGGATCC TGTCCTACAT CATGCTGCCC TGCAGTCTGC CCGTGGAGTC GGCTATCGCT 
GCAGTCCACA GGCTGGTGAC ATGGCTCCCT GATATCCAGG ATGATATCCA GTGGCTACAA 
TGGGCGACAT CCCAGGTTTG TGCCCGAATG ACGATGTGCC TGCTCCCCTC TACCAGCATG 
AGATTCCTGG GACAATCCCA ATTCCTTGGC CTCCATTGTA TCAAAGGGCT GAAAACCAAA 
GGGAAGGCAC AGCTGTCTCT TCAGCATGCC TCTTCTGCCA GAACCACTGC AAGGTTTGGT 
GCTCAGGCTG TGCAAACATT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006520409.1
CDS	609..1712
Translation	MEILMDLVRKARSRNIGTLHPFFNINKCIRDGLQESLPDNVHQVISGKVHISLTRVSDGENVLVSEFHSKDEVVDALVCSCFIPLFSGLIPPSFRGERYVDGGVSDNVPVLDAKTTITVSPFYGEHDICPKVKSTNFFHVNITNLSLRLCTGNLQLLTRALFPSDVKVMGELCYQGYLDAFRFLEENGICNGPQRSLSLSLVAPEACLENGKLVGDKVPVSLCFTDENIWETLSPELSTALSEAIKDREGYLSKVCNLLPVRILSYIMLPCSLPVESAIAAVHRLVTWLPDIQDDIQWLQWATSQVCARMTMCLLPSTSMRFLGQSQFLGLHCIKGLKTKGKAQLSLQHASSARTTARFGAQAVQTF

Target ORF information:

RefSeq Version	XM_006520346.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus patatin-like phospholipase domain containing 3 (Pnpla3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006520346.4

ORF Insert Sequence:

ATGGAGATCC TCATGGACCT CGTGCGGAAA GCCAGGAGCC GCAACATCGG CACCCTCCAC 
CCGTTCTTCA ACATTAACAA GTGCATCAGA GACGGGCTCC AGGAGAGCCT CCCAGACAAT 
GTCCACCAGG TCATTTCTGG CAAGGTTCAC ATCTCACTCA CCAGGGTGTC GGATGGGGAG 
AACGTGCTGG TGTCTGAGTT CCATTCCAAA GACGAAGTCG TGGATGCCCT GGTGTGTTCC 
TGCTTCATTC CCCTCTTCTC TGGCCTAATC CCTCCTTCCT TCCGAGGCGA GCGGTACGTG 
GACGGAGGAG TGAGCGACAA CGTCCCTGTG CTGGATGCCA AAACCACCAT CACGGTGTCA 
CCTTTCTACG GTGAGCATGA CATCTGCCCC AAAGTCAAGT CCACCAACTT CTTCCACGTG 
AATATCACCA ACCTCAGCCT CCGCCTCTGC ACTGGGAACC TCCAACTTCT GACCAGAGCG 
CTCTTCCCGT CTGATGTGAA GGTGATGGGA GAGCTGTGCT ATCAAGGGTA CCTGGACGCC 
TTCCGGTTCC TGGAGGAGAA TGGCATCTGT AACGGGCCAC AGCGCAGCCT GAGTCTGTCC 
TTGGTGGCGC CAGAAGCCTG CTTGGAAAAT GGCAAACTTG TGGGAGACAA GGTGCCAGTC 
AGCCTATGCT TTACAGATGA GAACATCTGG GAGACACTGT CCCCCGAGCT CAGCACAGCT 
CTGAGTGAAG CGATTAAGGA CAGGGAGGGC TACCTGAGCA AAGTCTGCAA CCTCCTGCCC 
GTCAGGATCC TGTCCTACAT CATGCTGCCC TGCAGTCTGC CCGTGGAGTC GGCTATCGCT 
GCAGTCCACA GGCTGGTGAC ATGGCTCCCT GATATCCAGG ATGATATCCA GTGGCTACAA 
TGGGCGACAT CCCAGGTTTG TGCCCGAATG ACGATGTGCC TGCTCCCCTC TACCAGCATG 
AGATTCCTGG GACAATCCCA ATTCCTTGGC CTCCATTGTA TCAAAGGGCT GAAAACCAAA 
GGGAAGGCAC AGCTGTCTCT TCAGCATGCC TCTTCTGCCA GAACCACTGC AAGGTTTGGT 
GCTCAGGCTG TGCAAACATT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The PNPLA3 variant associated with fatty liver disease (I148M) accumulates on lipid droplets by evading ubiquitylation.
Hepatology (Baltimore, Md.)66(4)1111-1124(2017 10)
BasuRay S,Smagris E,Cohen JC,Hobbs HH

Binge alcohol alters PNPLA3 levels in liver through epigenetic mechanism involving histone H3 acetylation.
Alcohol (Fayetteville, N.Y.)6077-82(2017 May)
Restrepo RJ,Lim RW,Korthuis RJ,Shukla SD

Activation of the Constitutive Androstane Receptor induces hepatic lipogenesis and regulates Pnpla3 gene expression in a LXR-independent way.
Toxicology and applied pharmacology30390-100(2016 07)
Marmugi A,Lukowicz C,Lasserre F,Montagner A,Polizzi A,Ducheix S,Goron A,Gamet-Payrastre L,Gerbal-Chaloin S,Pascussi JM,Moldes M,Pineau T,Guillou H,Mselli-Lakhal L

Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis.
Hepatology (Baltimore, Md.)61(1)108-18(2015 Jan)
Smagris E,BasuRay S,Li J,Huang Y,Lai KM,Gromada J,Cohen JC,Hobbs HH

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Pnpla3 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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