Kcnq3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kcnq3
Entrez Gene ID	110862
Full Name	potassium voltage-gated channel, subfamily Q, member 3
General protein information	Preferred Names potassium voltage-gated channel, subfamily Q, member 3 Names potassium voltage-gated channel subfamily KQT member 3 KQT-like 3 potassium channel subunit alpha KvLQT3 voltage-gated potassium channel subunit Kv7.3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15 D1\|15 29.16 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_152923.2	NP_690887.2	potassium voltage-gated channel subfamily KQT member 3
XM_011245408.3	XP_011243710.1	potassium voltage-gated channel subfamily KQT member 3 isoform X1
XM_011245408.2	XP_011243710.1	potassium voltage-gated channel subfamily KQT member 3 isoform X1
NM_152923.3	NP_690887.2	potassium voltage-gated channel subfamily KQT member 3

Pathways from BioSystems

Homologies

	KCNQ3	XP_001089122.1
Xenopus tropicalis (tropical clawed frog)	kcnq3	XP_004915103.1
Canis lupus familiaris (dog)	KCNQ3	XP_532334.3
Gallus gallus (chicken)	KCNQ3	XP_003640915.2
Danio rerio (zebrafish)	kcnq3	XP_003197981.1
Bos taurus (cattle)	KCNQ3	NP_776799.1
Homo sapiens (human)	KCNQ3	NP_004510.1
Pan troglodytes (chimpanzee)	KCNQ3	XP_519963.2
Mus musculus (house mouse)	Kcnq3	NP_690887.2
Rattus norvegicus (Norway rat)	Kcnq3	NP_113785.3

Gene Ontology
Bibliography

Related articles in PubMed

Ubiquitin-specific Protease 36 (USP36) Controls Neuronal Precursor Cell-expressed Developmentally Down-regulated 4-2 (Nedd4-2) Actions over the Neurotrophin Receptor TrkA and Potassium Voltage-gated Channels 7.2/3 (Kv7.2/3).
Anta B, Mart?n-Rodr?guez C, Gomis-Perez C, Calvo L, L?pez-Benito S, Calder?n-Garc?a AA, Vicente-Garc?a C, Villarroel ?, Ar?valo JC
The Journal of biological chemistry291(36)19132-45(2016 09)

KCNQ channel openers reverse depressive symptoms via an active resilience mechanism.
Friedman AK, Juarez B, Ku SM, Zhang H, Calizo RC, Walsh JJ, Chaudhury D, Zhang S, Hawkins A, Dietz DM, Murrough JW, Ribadeneira M, Wong EH, Neve RL, Han MH
Nature communications711671(2016 May)

KCNQ Potassium Channels Modulate Sensitivity of Skin Down-hair (D-hair) Mechanoreceptors.
Sch?tze S, Orozco IJ, Jentsch TJ
The Journal of biological chemistry291(11)5566-75(2016 Mar)

The Voltage Activation of Cortical KCNQ Channels Depends on Global PIP2 Levels.
Kim KS, Duignan KM, Hawryluk JM, Soh H, Tzingounis AV
Biophysical journal110(5)1089-98(2016 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

USP36 actions extend beyond TrkA because the presence of USP36 interferes with Nedd4-2-dependent Kv7.2/3 channel regulation.
Title: Ubiquitin-specific Protease 36 (USP36) Controls Neuronal Precursor Cell-expressed Developmentally Down-regulated 4-2 (Nedd4-2) Actions over the Neurotrophin Receptor TrkA and Potassium Voltage-gated Channels 7.2/3 (Kv7.2/3).

Mechanosensitivity of Skin Down-hair mechanoeceptors is increased in Kcnq3-/- and in Kcnq2+/-/Kcnq3-/- Mutant Mice.
Title: KCNQ Potassium Channels Modulate Sensitivity of Skin Down-hair (D-hair) Mechanoreceptors.

KCNQ3 plays an essential role in maintaining the slow afterhyperpolarization under low phosphatidylinositol diphosphate conditions.
Title: The Voltage Activation of Cortical KCNQ Channels Depends on Global PIP2 Levels.

Resilience to tinnitus is developed in mice that show a re-emergence of KCNQ2/3 channel activity and a reduction in HCN channel activity.
Title: Noise-induced plasticity of KCNQ2/3 and HCN channels underlies vulnerability and resilience to tinnitus.

Data show that a reduction in Kv7.2/3 channel activity is essential for tinnitus induction and for the tinnitus-specific hyperactivity.
Title: Pathogenic plasticity of Kv7.2/3 channel activity is essential for the induction of tinnitus.

The following Kcnq3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kcnq3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu72373	XM_011245408.3 Latest version!	Mus musculus potassium voltage-gated channel, subfamily Q, member 3 (Kcnq3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu02574	NM_152923.3 Latest version!	Mus musculus potassium voltage-gated channel, subfamily Q, member 3 (Kcnq3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$517.30 $739.00
View Old Accession Versions >>
OMu72373	XM_011245408.2	Mus musculus potassium voltage-gated channel, subfamily Q, member 3 (Kcnq3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu02574	NM_152923.2	Mus musculus potassium voltage-gated channel, subfamily Q, member 3 (Kcnq3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$517.30 $739.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kcnq3 ( XM_011245408.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011243710.1 Mus musculus potassium voltage-gated channel, subfamily Q, member 3 (Kcnq3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu72373
Clone ID Related Accession (Same CDS sequence)	XM_011245408.3 , XM_011245408.2
Accession Version	XM_011245408.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1374bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	potassium voltage-gated channel subfamily KQT member 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011245408.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTACCAA CCCCAACAGG TTGGATCTGG TGGCAACCTG GAGATTTTAT GAATCAGTTG 
TCTCTTTCCC ATTCTTCAGG AAAGAACAAC TGGAAGCAGC AGCCAGATGC CATAGAAGAA 
AGCCCTTCCA AAGAGCCAAA GCCTGTTGGC TTAAACAATA AAGAGCGTTT CCGCACCGCC 
TTCCGCATGA AAGCCTACGC TTTCTGGCAG AGTTCTGAAG ATGCTGGGAC AGGCGACCCC 
ATGGCAGAAG ACAGGGGCTA TGGGAATGAC TTCCTCATTG AAGACATGAT CCCTACCCTA 
AAGGCTGCCA TCCGAGCTGT CAGAATTCTA CAGTTCCGTC TATATAAAAA AAAGTTCAAG 
GAGACGTTGA GGCCTTATGA TGTGAAAGAT GTGATTGAGC AGTATTCGGC CGGACATCTT 
GACATGCTTT CCAGGATAAA GTACCTACAG ACAAGAATAG ATATGATTTT CACCCCTGGA 
CCTCCATCCA CTCCAAAACA TAAGAAGTCT CAGAAAGGGT CAGCATTTAC CTACCCATCC 
CAGCAGTCTC CAAGGAATGA ACCATATGTA GCCAGGGCAG CCACATCAGA AACTGAAGAC 
CAAAGCATGA TGGGGAAGTT TGTAAAAGTT GAAAGACAGG TTCATGACAT GGGGAAGAAA 
CTGGACTTCC TCGTGGACAT GCATATGCAG CATATGGAAC GCTTACAGGT ACATGTCACT 
GAGTACTACC CAACTAAGGG GGCCTCCTCC CCAGCCGAAG GGGAGAAGAA AGAAGACAAC 
AGGTACTCTG ATTTGAAAAC CATCATCTGC AACTACTCAG AGACAGGGCC CCCTGACCCT 
CCTTACAGCT TCCACCAGGT GCCCATCGAC AGAGTTGGCC CTTACGGGTT TTTTGCACAT 
GATCCTGTGA AACTGACCCG AGGGGGACCC AGTTCTACAA AGGCTCAAGC TAACCTTCCC 
TCCTCGGGAA GTACATATGC AGAGAGGCCC ACAGTCCTGC CCATCTTGAC TCTTCTGGAC 
TCATGTGTGA GCTACCACTC CCAGACAGAA CTGCAAGGTC CCTATTCGGA CCACATCTCG 
CCCCGCCAGA GACGCAGCAT CACTAGGGAC AGTGATACAC CTCTGTCCCT CATGTCCGTC 
AATCACGAGG AACTGGAGCG GTCTCCAAGT GGCTTCAGCA TCTCACAAGA CAGAGATGAT 
TATGTATTTG GCCCCAGTGG GGGATCGAGC TGGATGAGGG AAAAGCGGTA CCTGGCTGAA 
GGAGAAACGG ACACGGACAC AGACCCCTTC ACACCCAGTG GTTCCATGCC TATGTCATCC 
ACTGGGGATG GTATTTCAGA TTCCATATGG ACCCCTTCCA ACAAGCCCAC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011243710.1
CDS	103..1476
Translation	MLPTPTGWIWWQPGDFMNQLSLSHSSGKNNWKQQPDAIEESPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTGDPMAEDRGYGNDFLIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTYPSQQSPRNEPYVARAATSETEDQSMMGKFVKVERQVHDMGKKLDFLVDMHMQHMERLQVHVTEYYPTKGASSPAEGEKKEDNRYSDLKTIICNYSETGPPDPPYSFHQVPIDRVGPYGFFAHDPVKLTRGGPSSTKAQANLPSSGSTYAERPTVLPILTLLDSCVSYHSQTELQGPYSDHISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPSGGSSWMREKRYLAEGETDTDTDPFTPSGSMPMSSTGDGISDSIWTPSNKPT

Target ORF information:

RefSeq Version	XM_011245408.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus potassium voltage-gated channel, subfamily Q, member 3 (Kcnq3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011245408.2

ORF Insert Sequence:

ATGCTACCAA CCCCAACAGG TTGGATCTGG TGGCAACCTG GAGATTTTAT GAATCAGTTG 
TCTCTTTCCC ATTCTTCAGG AAAGAACAAC TGGAAGCAGC AGCCAGATGC CATAGAAGAA 
AGCCCTTCCA AAGAGCCAAA GCCTGTTGGC TTAAACAATA AAGAGCGTTT CCGCACCGCC 
TTCCGCATGA AAGCCTACGC TTTCTGGCAG AGTTCTGAAG ATGCTGGGAC AGGCGACCCC 
ATGGCAGAAG ACAGGGGCTA TGGGAATGAC TTCCTCATTG AAGACATGAT CCCTACCCTA 
AAGGCTGCCA TCCGAGCTGT CAGAATTCTA CAGTTCCGTC TATATAAAAA AAAGTTCAAG 
GAGACGTTGA GGCCTTATGA TGTGAAAGAT GTGATTGAGC AGTATTCGGC CGGACATCTT 
GACATGCTTT CCAGGATAAA GTACCTACAG ACAAGAATAG ATATGATTTT CACCCCTGGA 
CCTCCATCCA CTCCAAAACA TAAGAAGTCT CAGAAAGGGT CAGCATTTAC CTACCCATCC 
CAGCAGTCTC CAAGGAATGA ACCATATGTA GCCAGGGCAG CCACATCAGA AACTGAAGAC 
CAAAGCATGA TGGGGAAGTT TGTAAAAGTT GAAAGACAGG TTCATGACAT GGGGAAGAAA 
CTGGACTTCC TCGTGGACAT GCATATGCAG CATATGGAAC GCTTACAGGT ACATGTCACT 
GAGTACTACC CAACTAAGGG GGCCTCCTCC CCAGCCGAAG GGGAGAAGAA AGAAGACAAC 
AGGTACTCTG ATTTGAAAAC CATCATCTGC AACTACTCAG AGACAGGGCC CCCTGACCCT 
CCTTACAGCT TCCACCAGGT GCCCATCGAC AGAGTTGGCC CTTACGGGTT TTTTGCACAT 
GATCCTGTGA AACTGACCCG AGGGGGACCC AGTTCTACAA AGGCTCAAGC TAACCTTCCC 
TCCTCGGGAA GTACATATGC AGAGAGGCCC ACAGTCCTGC CCATCTTGAC TCTTCTGGAC 
TCATGTGTGA GCTACCACTC CCAGACAGAA CTGCAAGGTC CCTATTCGGA CCACATCTCG 
CCCCGCCAGA GACGCAGCAT CACTAGGGAC AGTGATACAC CTCTGTCCCT CATGTCCGTC 
AATCACGAGG AACTGGAGCG GTCTCCAAGT GGCTTCAGCA TCTCACAAGA CAGAGATGAT 
TATGTATTTG GCCCCAGTGG GGGATCGAGC TGGATGAGGG AAAAGCGGTA CCTGGCTGAA 
GGAGAAACGG ACACGGACAC AGACCCCTTC ACACCCAGTG GTTCCATGCC TATGTCATCC 
ACTGGGGATG GTATTTCAGA TTCCATATGG ACCCCTTCCA ACAAGCCCAC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kcnq3 ( XM_011245408.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011243710.1 Mus musculus potassium voltage-gated channel, subfamily Q, member 3 (Kcnq3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu72373
Clone ID Related Accession (Same CDS sequence)	XM_011245408.3 , XM_011245408.2
Accession Version	XM_011245408.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1374bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	potassium voltage-gated channel subfamily KQT member 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011245408.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTACCAA CCCCAACAGG TTGGATCTGG TGGCAACCTG GAGATTTTAT GAATCAGTTG 
TCTCTTTCCC ATTCTTCAGG AAAGAACAAC TGGAAGCAGC AGCCAGATGC CATAGAAGAA 
AGCCCTTCCA AAGAGCCAAA GCCTGTTGGC TTAAACAATA AAGAGCGTTT CCGCACCGCC 
TTCCGCATGA AAGCCTACGC TTTCTGGCAG AGTTCTGAAG ATGCTGGGAC AGGCGACCCC 
ATGGCAGAAG ACAGGGGCTA TGGGAATGAC TTCCTCATTG AAGACATGAT CCCTACCCTA 
AAGGCTGCCA TCCGAGCTGT CAGAATTCTA CAGTTCCGTC TATATAAAAA AAAGTTCAAG 
GAGACGTTGA GGCCTTATGA TGTGAAAGAT GTGATTGAGC AGTATTCGGC CGGACATCTT 
GACATGCTTT CCAGGATAAA GTACCTACAG ACAAGAATAG ATATGATTTT CACCCCTGGA 
CCTCCATCCA CTCCAAAACA TAAGAAGTCT CAGAAAGGGT CAGCATTTAC CTACCCATCC 
CAGCAGTCTC CAAGGAATGA ACCATATGTA GCCAGGGCAG CCACATCAGA AACTGAAGAC 
CAAAGCATGA TGGGGAAGTT TGTAAAAGTT GAAAGACAGG TTCATGACAT GGGGAAGAAA 
CTGGACTTCC TCGTGGACAT GCATATGCAG CATATGGAAC GCTTACAGGT ACATGTCACT 
GAGTACTACC CAACTAAGGG GGCCTCCTCC CCAGCCGAAG GGGAGAAGAA AGAAGACAAC 
AGGTACTCTG ATTTGAAAAC CATCATCTGC AACTACTCAG AGACAGGGCC CCCTGACCCT 
CCTTACAGCT TCCACCAGGT GCCCATCGAC AGAGTTGGCC CTTACGGGTT TTTTGCACAT 
GATCCTGTGA AACTGACCCG AGGGGGACCC AGTTCTACAA AGGCTCAAGC TAACCTTCCC 
TCCTCGGGAA GTACATATGC AGAGAGGCCC ACAGTCCTGC CCATCTTGAC TCTTCTGGAC 
TCATGTGTGA GCTACCACTC CCAGACAGAA CTGCAAGGTC CCTATTCGGA CCACATCTCG 
CCCCGCCAGA GACGCAGCAT CACTAGGGAC AGTGATACAC CTCTGTCCCT CATGTCCGTC 
AATCACGAGG AACTGGAGCG GTCTCCAAGT GGCTTCAGCA TCTCACAAGA CAGAGATGAT 
TATGTATTTG GCCCCAGTGG GGGATCGAGC TGGATGAGGG AAAAGCGGTA CCTGGCTGAA 
GGAGAAACGG ACACGGACAC AGACCCCTTC ACACCCAGTG GTTCCATGCC TATGTCATCC 
ACTGGGGATG GTATTTCAGA TTCCATATGG ACCCCTTCCA ACAAGCCCAC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011243710.1
CDS	113..1486
Translation	MLPTPTGWIWWQPGDFMNQLSLSHSSGKNNWKQQPDAIEESPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTGDPMAEDRGYGNDFLIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTYPSQQSPRNEPYVARAATSETEDQSMMGKFVKVERQVHDMGKKLDFLVDMHMQHMERLQVHVTEYYPTKGASSPAEGEKKEDNRYSDLKTIICNYSETGPPDPPYSFHQVPIDRVGPYGFFAHDPVKLTRGGPSSTKAQANLPSSGSTYAERPTVLPILTLLDSCVSYHSQTELQGPYSDHISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPSGGSSWMREKRYLAEGETDTDTDPFTPSGSMPMSSTGDGISDSIWTPSNKPT

Target ORF information:

RefSeq Version	XM_011245408.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus potassium voltage-gated channel, subfamily Q, member 3 (Kcnq3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011245408.3

ORF Insert Sequence:

ATGCTACCAA CCCCAACAGG TTGGATCTGG TGGCAACCTG GAGATTTTAT GAATCAGTTG 
TCTCTTTCCC ATTCTTCAGG AAAGAACAAC TGGAAGCAGC AGCCAGATGC CATAGAAGAA 
AGCCCTTCCA AAGAGCCAAA GCCTGTTGGC TTAAACAATA AAGAGCGTTT CCGCACCGCC 
TTCCGCATGA AAGCCTACGC TTTCTGGCAG AGTTCTGAAG ATGCTGGGAC AGGCGACCCC 
ATGGCAGAAG ACAGGGGCTA TGGGAATGAC TTCCTCATTG AAGACATGAT CCCTACCCTA 
AAGGCTGCCA TCCGAGCTGT CAGAATTCTA CAGTTCCGTC TATATAAAAA AAAGTTCAAG 
GAGACGTTGA GGCCTTATGA TGTGAAAGAT GTGATTGAGC AGTATTCGGC CGGACATCTT 
GACATGCTTT CCAGGATAAA GTACCTACAG ACAAGAATAG ATATGATTTT CACCCCTGGA 
CCTCCATCCA CTCCAAAACA TAAGAAGTCT CAGAAAGGGT CAGCATTTAC CTACCCATCC 
CAGCAGTCTC CAAGGAATGA ACCATATGTA GCCAGGGCAG CCACATCAGA AACTGAAGAC 
CAAAGCATGA TGGGGAAGTT TGTAAAAGTT GAAAGACAGG TTCATGACAT GGGGAAGAAA 
CTGGACTTCC TCGTGGACAT GCATATGCAG CATATGGAAC GCTTACAGGT ACATGTCACT 
GAGTACTACC CAACTAAGGG GGCCTCCTCC CCAGCCGAAG GGGAGAAGAA AGAAGACAAC 
AGGTACTCTG ATTTGAAAAC CATCATCTGC AACTACTCAG AGACAGGGCC CCCTGACCCT 
CCTTACAGCT TCCACCAGGT GCCCATCGAC AGAGTTGGCC CTTACGGGTT TTTTGCACAT 
GATCCTGTGA AACTGACCCG AGGGGGACCC AGTTCTACAA AGGCTCAAGC TAACCTTCCC 
TCCTCGGGAA GTACATATGC AGAGAGGCCC ACAGTCCTGC CCATCTTGAC TCTTCTGGAC 
TCATGTGTGA GCTACCACTC CCAGACAGAA CTGCAAGGTC CCTATTCGGA CCACATCTCG 
CCCCGCCAGA GACGCAGCAT CACTAGGGAC AGTGATACAC CTCTGTCCCT CATGTCCGTC 
AATCACGAGG AACTGGAGCG GTCTCCAAGT GGCTTCAGCA TCTCACAAGA CAGAGATGAT 
TATGTATTTG GCCCCAGTGG GGGATCGAGC TGGATGAGGG AAAAGCGGTA CCTGGCTGAA 
GGAGAAACGG ACACGGACAC AGACCCCTTC ACACCCAGTG GTTCCATGCC TATGTCATCC 
ACTGGGGATG GTATTTCAGA TTCCATATGG ACCCCTTCCA ACAAGCCCAC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kcnq3 ( NM_152923.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_690887.2 Mus musculus potassium voltage-gated channel, subfamily Q, member 3 (Kcnq3), mRNA.

Price & Availability↑

CloneID	OMu02574
Clone ID Related Accession (Same CDS sequence)	NM_152923.2 , NM_152923.3
Accession Version	NM_152923.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2622bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-21
Organism	Mus musculus(house mouse)
Product	potassium voltage-gated channel subfamily KQT member 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY118171.1, AC110897.11 and AW494964.1. On Dec 30, 2009 this sequence version replaced NM_152923.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY118171.1, BC116306.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849378 [ECO:0000350] ##Evidence-Data-END##

ATGGGTCTCA AGGCTCGCAG GGCGGCGGGG GCGGCTGGCG GGGGCGGCGG CGAAGGGGGC 
GGCGGCGGCG GCGGGGCCGC TAACCCTGCT GGAGGGGACT CGGCGGTGGC CGGCGACGAG 
GAGCGGAAAG TGGGGCTGGC GCCAGGAGAC GTGGAGCAAG TCACCTTGGC GCTAGGGGCC 
GGAGCCGACA AAGACGGGAC CCTGCTGCTG GAGGGCGGTG GCCGCGAAGA GGGGCAGAGG 
AGGACCCCGC AGGGCATCGG GCTCCTGGCA AAGACCCCCC TGAGCCGCCC AGTCAAGAGG 
AACAACGCCA AGTACAGGCG CATCCAAACT TTGATCTATG ACGCCCTGGA GAGACCGCGG 
GGCTGGGCGC TGCTCTACCA CGCGCTTGTG TTCCTGATTG TCCTGGGATG CTTGATTCTG 
GCCGTGCTCA CCACCTTCAA GGAATATGAG ACTGTGTCTG GAGACTGGCT TTTGCTGCTG 
GAAACCTTTG CTATTTTCAT CTTTGGAGCT GAGTTTGCTT TGAGGATCTG GGCTGCAGGA 
TGTTGCTGTC GATACAAAGG CTGGCGTGGA CGGCTAAAGT TTGCCAGGAA GCCCCTGTGC 
ATGTTGGACA TCTTCGTACT GATTGCCTCT GTGCCAGTGG TTGCCGTGGG AAACCAGGGC 
AATGTCTTGG CCACCTCCCT GCGAAGCCTT CGCTTCCTGC AGATCCTGCG CATGCTTCGA 
ATGGATAGGA GGGGTGGCAC CTGGAAGCTC CTGGGCTCGG CTATCTGTGC CCACAGCAAA 
GAACTCATCA CTGCCTGGTA CATAGGCTTC CTGACACTCA TCCTTTCTTC ATTTCTTGTC 
TACCTGGTGG AGAAGGATGT GCCAGAGATG GATGCCCAAG GAGAGGAAAT GAAGGAGGAG 
TTTGAGACCT ATGCAGATGC TCTGTGGTGG GGCCTGATCA CACTGGCCAC CATTGGTTAT 
GGAGACAAGA CACCTAAAAC CTGGGAAGGA CGTCTGATTG CTGCCACCTT TTCTTTAATC 
GGCGTCTCCT TTTTTGCCCT TCCGGCAGGC ATCCTTGGCT CAGGACTGGC ACTGAAGGTT 
CAGGAGCAGC ACCGTCAGAA GCACTTTGAG AAGAGAAGGA AGCCAGCTGC GGAACTCATC 
CAGGCTGCCT GGAGATATTA TGCTACCAAC CCCAACAGGT TGGATCTGGT GGCAACCTGG 
AGATTTTATG AATCAGTTGT CTCTTTCCCA TTCTTCAGGA AAGAACAACT GGAAGCAGCA 
GCCAGCCAAA AGCTGGGTCT CTTGGATCGG GTTCGCCTTT CTAATCCTCG TGGTAGCAAT 
ACTAAAGGAA AGCTATTTAC CCCTCTGAAT GTAGATGCCA TAGAAGAAAG CCCTTCCAAA 
GAGCCAAAGC CTGTTGGCTT AAACAATAAA GAGCGTTTCC GCACCGCCTT CCGCATGAAA 
GCCTACGCTT TCTGGCAGAG TTCTGAAGAT GCTGGGACAG GCGACCCCAT GGCAGAAGAC 
AGGGGCTATG GGAATGACTT CCTCATTGAA GACATGATCC CTACCCTAAA GGCTGCCATC 
CGAGCTGTCA GAATTCTACA GTTCCGTCTA TATAAAAAAA AGTTCAAGGA GACGTTGAGG 
CCTTATGATG TGAAAGATGT GATTGAGCAG TATTCGGCCG GACATCTTGA CATGCTTTCC 
AGGATAAAGT ACCTACAGAC AAGAATAGAT ATGATTTTCA CCCCTGGACC TCCATCCACT 
CCAAAACATA AGAAGTCTCA GAAAGGGTCA GCATTTACCT ACCCATCCCA GCAGTCTCCA 
AGGAATGAAC CATATGTAGC CAGGGCAGCC ACATCAGAAA CTGAAGACCA AAGCATGATG 
GGGAAGTTTG TAAAAGTTGA AAGACAGGTT CATGACATGG GGAAGAAACT GGACTTCCTC 
GTGGACATGC ATATGCAGCA TATGGAACGC TTACAGGTAC ATGTCACTGA GTACTACCCA 
ACTAAGGGGG CCTCCTCCCC AGCCGAAGGG GAGAAGAAAG AAGACAACAG GTACTCTGAT 
TTGAAAACCA TCATCTGCAA CTACTCAGAG ACAGGGCCCC CTGACCCTCC TTACAGCTTC 
CACCAGGTGC CCATCGACAG AGTTGGCCCT TACGGGTTTT TTGCACATGA TCCTGTGAAA 
CTGACCCGAG GGGGACCCAG TTCTACAAAG GCTCAAGCTA ACCTTCCCTC CTCGGGAAGT 
ACATATGCAG AGAGGCCCAC AGTCCTGCCC ATCTTGACTC TTCTGGACTC ATGTGTGAGC 
TACCACTCCC AGACAGAACT GCAAGGTCCC TATTCGGACC ACATCTCGCC CCGCCAGAGA 
CGCAGCATCA CTAGGGACAG TGATACACCT CTGTCCCTCA TGTCCGTCAA TCACGAGGAA 
CTGGAGCGGT CTCCAAGTGG CTTCAGCATC TCACAAGACA GAGATGATTA TGTATTTGGC 
CCCAGTGGGG GATCGAGCTG GATGAGGGAA AAGCGGTACC TGGCTGAAGG AGAAACGGAC 
ACGGACACAG ACCCCTTCAC ACCCAGTGGT TCCATGCCTA TGTCATCCAC TGGGGATGGT 
ATTTCAGATT CCATATGGAC CCCTTCCAAC AAGCCCACTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_690887.2
CDS	1..2622
Translation	MGLKARRAAGAAGGGGGEGGGGGGGAANPAGGDSAVAGDEERKVGLAPGDVEQVTLALGAGADKDGTLLLEGGGREEGQRRTPQGIGLLAKTPLSRPVKRNNAKYRRIQTLIYDALERPRGWALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEMDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRLDLVATWRFYESVVSFPFFRKEQLEAAASQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTGDPMAEDRGYGNDFLIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTYPSQQSPRNEPYVARAATSETEDQSMMGKFVKVERQVHDMGKKLDFLVDMHMQHMERLQVHVTEYYPTKGASSPAEGEKKEDNRYSDLKTIICNYSETGPPDPPYSFHQVPIDRVGPYGFFAHDPVKLTRGGPSSTKAQANLPSSGSTYAERPTVLPILTLLDSCVSYHSQTELQGPYSDHISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPSGGSSWMREKRYLAEGETDTDTDPFTPSGSMPMSSTGDGISDSIWTPSNKPT

Target ORF information:

RefSeq Version	NM_152923.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus potassium voltage-gated channel, subfamily Q, member 3 (Kcnq3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_152923.2

ORF Insert Sequence:

ATGGGTCTCA AGGCTCGCAG GGCGGCGGGG GCGGCTGGCG GGGGCGGCGG CGAAGGGGGC 
GGCGGCGGCG GCGGGGCCGC TAACCCTGCT GGAGGGGACT CGGCGGTGGC CGGCGACGAG 
GAGCGGAAAG TGGGGCTGGC GCCAGGAGAC GTGGAGCAAG TCACCTTGGC GCTAGGGGCC 
GGAGCCGACA AAGACGGGAC CCTGCTGCTG GAGGGCGGTG GCCGCGAAGA GGGGCAGAGG 
AGGACCCCGC AGGGCATCGG GCTCCTGGCA AAGACCCCCC TGAGCCGCCC AGTCAAGAGG 
AACAACGCCA AGTACAGGCG CATCCAAACT TTGATCTATG ACGCCCTGGA GAGACCGCGG 
GGCTGGGCGC TGCTCTACCA CGCGCTTGTG TTCCTGATTG TCCTGGGATG CTTGATTCTG 
GCCGTGCTCA CCACCTTCAA GGAATATGAG ACTGTGTCTG GAGACTGGCT TTTGCTGCTG 
GAAACCTTTG CTATTTTCAT CTTTGGAGCT GAGTTTGCTT TGAGGATCTG GGCTGCAGGA 
TGTTGCTGTC GATACAAAGG CTGGCGTGGA CGGCTAAAGT TTGCCAGGAA GCCCCTGTGC 
ATGTTGGACA TCTTCGTACT GATTGCCTCT GTGCCAGTGG TTGCCGTGGG AAACCAGGGC 
AATGTCTTGG CCACCTCCCT GCGAAGCCTT CGCTTCCTGC AGATCCTGCG CATGCTTCGA 
ATGGATAGGA GGGGTGGCAC CTGGAAGCTC CTGGGCTCGG CTATCTGTGC CCACAGCAAA 
GAACTCATCA CTGCCTGGTA CATAGGCTTC CTGACACTCA TCCTTTCTTC ATTTCTTGTC 
TACCTGGTGG AGAAGGATGT GCCAGAGATG GATGCCCAAG GAGAGGAAAT GAAGGAGGAG 
TTTGAGACCT ATGCAGATGC TCTGTGGTGG GGCCTGATCA CACTGGCCAC CATTGGTTAT 
GGAGACAAGA CACCTAAAAC CTGGGAAGGA CGTCTGATTG CTGCCACCTT TTCTTTAATC 
GGCGTCTCCT TTTTTGCCCT TCCGGCAGGC ATCCTTGGCT CAGGACTGGC ACTGAAGGTT 
CAGGAGCAGC ACCGTCAGAA GCACTTTGAG AAGAGAAGGA AGCCAGCTGC GGAACTCATC 
CAGGCTGCCT GGAGATATTA TGCTACCAAC CCCAACAGGT TGGATCTGGT GGCAACCTGG 
AGATTTTATG AATCAGTTGT CTCTTTCCCA TTCTTCAGGA AAGAACAACT GGAAGCAGCA 
GCCAGCCAAA AGCTGGGTCT CTTGGATCGG GTTCGCCTTT CTAATCCTCG TGGTAGCAAT 
ACTAAAGGAA AGCTATTTAC CCCTCTGAAT GTAGATGCCA TAGAAGAAAG CCCTTCCAAA 
GAGCCAAAGC CTGTTGGCTT AAACAATAAA GAGCGTTTCC GCACCGCCTT CCGCATGAAA 
GCCTACGCTT TCTGGCAGAG TTCTGAAGAT GCTGGGACAG GCGACCCCAT GGCAGAAGAC 
AGGGGCTATG GGAATGACTT CCTCATTGAA GACATGATCC CTACCCTAAA GGCTGCCATC 
CGAGCTGTCA GAATTCTACA GTTCCGTCTA TATAAAAAAA AGTTCAAGGA GACGTTGAGG 
CCTTATGATG TGAAAGATGT GATTGAGCAG TATTCGGCCG GACATCTTGA CATGCTTTCC 
AGGATAAAGT ACCTACAGAC AAGAATAGAT ATGATTTTCA CCCCTGGACC TCCATCCACT 
CCAAAACATA AGAAGTCTCA GAAAGGGTCA GCATTTACCT ACCCATCCCA GCAGTCTCCA 
AGGAATGAAC CATATGTAGC CAGGGCAGCC ACATCAGAAA CTGAAGACCA AAGCATGATG 
GGGAAGTTTG TAAAAGTTGA AAGACAGGTT CATGACATGG GGAAGAAACT GGACTTCCTC 
GTGGACATGC ATATGCAGCA TATGGAACGC TTACAGGTAC ATGTCACTGA GTACTACCCA 
ACTAAGGGGG CCTCCTCCCC AGCCGAAGGG GAGAAGAAAG AAGACAACAG GTACTCTGAT 
TTGAAAACCA TCATCTGCAA CTACTCAGAG ACAGGGCCCC CTGACCCTCC TTACAGCTTC 
CACCAGGTGC CCATCGACAG AGTTGGCCCT TACGGGTTTT TTGCACATGA TCCTGTGAAA 
CTGACCCGAG GGGGACCCAG TTCTACAAAG GCTCAAGCTA ACCTTCCCTC CTCGGGAAGT 
ACATATGCAG AGAGGCCCAC AGTCCTGCCC ATCTTGACTC TTCTGGACTC ATGTGTGAGC 
TACCACTCCC AGACAGAACT GCAAGGTCCC TATTCGGACC ACATCTCGCC CCGCCAGAGA 
CGCAGCATCA CTAGGGACAG TGATACACCT CTGTCCCTCA TGTCCGTCAA TCACGAGGAA 
CTGGAGCGGT CTCCAAGTGG CTTCAGCATC TCACAAGACA GAGATGATTA TGTATTTGGC 
CCCAGTGGGG GATCGAGCTG GATGAGGGAA AAGCGGTACC TGGCTGAAGG AGAAACGGAC 
ACGGACACAG ACCCCTTCAC ACCCAGTGGT TCCATGCCTA TGTCATCCAC TGGGGATGGT 
ATTTCAGATT CCATATGGAC CCCTTCCAAC AAGCCCACTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kcnq3 ( NM_152923.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_690887.2 Mus musculus potassium voltage-gated channel, subfamily Q, member 3 (Kcnq3), mRNA.

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CloneID	OMu02574
Clone ID Related Accession (Same CDS sequence)	NM_152923.2 , NM_152923.3
Accession Version	NM_152923.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2622bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Mus musculus(house mouse)
Product	potassium voltage-gated channel subfamily KQT member 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC110897.11, AC102633.8 and AC091276.7. On Jun 24, 2019 this sequence version replaced NM_152923.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY118171.1, BC116306.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849378 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGTCTCA AGGCTCGCAG GGCGGCGGGG GCGGCTGGCG GGGGCGGCGG CGAAGGGGGC 
GGCGGCGGCG GCGGGGCCGC TAACCCTGCT GGAGGGGACT CGGCGGTGGC CGGCGACGAG 
GAGCGGAAAG TGGGGCTGGC GCCAGGAGAC GTGGAGCAAG TCACCTTGGC GCTAGGGGCC 
GGAGCCGACA AAGACGGGAC CCTGCTGCTG GAGGGCGGTG GCCGCGAAGA GGGGCAGAGG 
AGGACCCCGC AGGGCATCGG GCTCCTGGCA AAGACCCCCC TGAGCCGCCC AGTCAAGAGG 
AACAACGCCA AGTACAGGCG CATCCAAACT TTGATCTATG ACGCCCTGGA GAGACCGCGG 
GGCTGGGCGC TGCTCTACCA CGCGCTTGTG TTCCTGATTG TCCTGGGATG CTTGATTCTG 
GCCGTGCTCA CCACCTTCAA GGAATATGAG ACTGTGTCTG GAGACTGGCT TTTGCTGCTG 
GAAACCTTTG CTATTTTCAT CTTTGGAGCT GAGTTTGCTT TGAGGATCTG GGCTGCAGGA 
TGTTGCTGTC GATACAAAGG CTGGCGTGGA CGGCTAAAGT TTGCCAGGAA GCCCCTGTGC 
ATGTTGGACA TCTTCGTACT GATTGCCTCT GTGCCAGTGG TTGCCGTGGG AAACCAGGGC 
AATGTCTTGG CCACCTCCCT GCGAAGCCTT CGCTTCCTGC AGATCCTGCG CATGCTTCGA 
ATGGATAGGA GGGGTGGCAC CTGGAAGCTC CTGGGCTCGG CTATCTGTGC CCACAGCAAA 
GAACTCATCA CTGCCTGGTA CATAGGCTTC CTGACACTCA TCCTTTCTTC ATTTCTTGTC 
TACCTGGTGG AGAAGGATGT GCCAGAGATG GATGCCCAAG GAGAGGAAAT GAAGGAGGAG 
TTTGAGACCT ATGCAGATGC TCTGTGGTGG GGCCTGATCA CACTGGCCAC CATTGGTTAT 
GGAGACAAGA CACCTAAAAC CTGGGAAGGA CGTCTGATTG CTGCCACCTT TTCTTTAATC 
GGCGTCTCCT TTTTTGCCCT TCCGGCAGGC ATCCTTGGCT CAGGACTGGC ACTGAAGGTT 
CAGGAGCAGC ACCGTCAGAA GCACTTTGAG AAGAGAAGGA AGCCAGCTGC GGAACTCATC 
CAGGCTGCCT GGAGATATTA TGCTACCAAC CCCAACAGGT TGGATCTGGT GGCAACCTGG 
AGATTTTATG AATCAGTTGT CTCTTTCCCA TTCTTCAGGA AAGAACAACT GGAAGCAGCA 
GCCAGCCAAA AGCTGGGTCT CTTGGATCGG GTTCGCCTTT CTAATCCTCG TGGTAGCAAT 
ACTAAAGGAA AGCTATTTAC CCCTCTGAAT GTAGATGCCA TAGAAGAAAG CCCTTCCAAA 
GAGCCAAAGC CTGTTGGCTT AAACAATAAA GAGCGTTTCC GCACCGCCTT CCGCATGAAA 
GCCTACGCTT TCTGGCAGAG TTCTGAAGAT GCTGGGACAG GCGACCCCAT GGCAGAAGAC 
AGGGGCTATG GGAATGACTT CCTCATTGAA GACATGATCC CTACCCTAAA GGCTGCCATC 
CGAGCTGTCA GAATTCTACA GTTCCGTCTA TATAAAAAAA AGTTCAAGGA GACGTTGAGG 
CCTTATGATG TGAAAGATGT GATTGAGCAG TATTCGGCCG GACATCTTGA CATGCTTTCC 
AGGATAAAGT ACCTACAGAC AAGAATAGAT ATGATTTTCA CCCCTGGACC TCCATCCACT 
CCAAAACATA AGAAGTCTCA GAAAGGGTCA GCATTTACCT ACCCATCCCA GCAGTCTCCA 
AGGAATGAAC CATATGTAGC CAGGGCAGCC ACATCAGAAA CTGAAGACCA AAGCATGATG 
GGGAAGTTTG TAAAAGTTGA AAGACAGGTT CATGACATGG GGAAGAAACT GGACTTCCTC 
GTGGACATGC ATATGCAGCA TATGGAACGC TTACAGGTAC ATGTCACTGA GTACTACCCA 
ACTAAGGGGG CCTCCTCCCC AGCCGAAGGG GAGAAGAAAG AAGACAACAG GTACTCTGAT 
TTGAAAACCA TCATCTGCAA CTACTCAGAG ACAGGGCCCC CTGACCCTCC TTACAGCTTC 
CACCAGGTGC CCATCGACAG AGTTGGCCCT TACGGGTTTT TTGCACATGA TCCTGTGAAA 
CTGACCCGAG GGGGACCCAG TTCTACAAAG GCTCAAGCTA ACCTTCCCTC CTCGGGAAGT 
ACATATGCAG AGAGGCCCAC AGTCCTGCCC ATCTTGACTC TTCTGGACTC ATGTGTGAGC 
TACCACTCCC AGACAGAACT GCAAGGTCCC TATTCGGACC ACATCTCGCC CCGCCAGAGA 
CGCAGCATCA CTAGGGACAG TGATACACCT CTGTCCCTCA TGTCCGTCAA TCACGAGGAA 
CTGGAGCGGT CTCCAAGTGG CTTCAGCATC TCACAAGACA GAGATGATTA TGTATTTGGC 
CCCAGTGGGG GATCGAGCTG GATGAGGGAA AAGCGGTACC TGGCTGAAGG AGAAACGGAC 
ACGGACACAG ACCCCTTCAC ACCCAGTGGT TCCATGCCTA TGTCATCCAC TGGGGATGGT 
ATTTCAGATT CCATATGGAC CCCTTCCAAC AAGCCCACTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_690887.2
CDS	406..3027
Translation	MGLKARRAAGAAGGGGGEGGGGGGGAANPAGGDSAVAGDEERKVGLAPGDVEQVTLALGAGADKDGTLLLEGGGREEGQRRTPQGIGLLAKTPLSRPVKRNNAKYRRIQTLIYDALERPRGWALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEMDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRLDLVATWRFYESVVSFPFFRKEQLEAAASQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTGDPMAEDRGYGNDFLIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTYPSQQSPRNEPYVARAATSETEDQSMMGKFVKVERQVHDMGKKLDFLVDMHMQHMERLQVHVTEYYPTKGASSPAEGEKKEDNRYSDLKTIICNYSETGPPDPPYSFHQVPIDRVGPYGFFAHDPVKLTRGGPSSTKAQANLPSSGSTYAERPTVLPILTLLDSCVSYHSQTELQGPYSDHISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPSGGSSWMREKRYLAEGETDTDTDPFTPSGSMPMSSTGDGISDSIWTPSNKPT

Target ORF information:

RefSeq Version	NM_152923.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus potassium voltage-gated channel, subfamily Q, member 3 (Kcnq3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_152923.3

ORF Insert Sequence:

ATGGGTCTCA AGGCTCGCAG GGCGGCGGGG GCGGCTGGCG GGGGCGGCGG CGAAGGGGGC 
GGCGGCGGCG GCGGGGCCGC TAACCCTGCT GGAGGGGACT CGGCGGTGGC CGGCGACGAG 
GAGCGGAAAG TGGGGCTGGC GCCAGGAGAC GTGGAGCAAG TCACCTTGGC GCTAGGGGCC 
GGAGCCGACA AAGACGGGAC CCTGCTGCTG GAGGGCGGTG GCCGCGAAGA GGGGCAGAGG 
AGGACCCCGC AGGGCATCGG GCTCCTGGCA AAGACCCCCC TGAGCCGCCC AGTCAAGAGG 
AACAACGCCA AGTACAGGCG CATCCAAACT TTGATCTATG ACGCCCTGGA GAGACCGCGG 
GGCTGGGCGC TGCTCTACCA CGCGCTTGTG TTCCTGATTG TCCTGGGATG CTTGATTCTG 
GCCGTGCTCA CCACCTTCAA GGAATATGAG ACTGTGTCTG GAGACTGGCT TTTGCTGCTG 
GAAACCTTTG CTATTTTCAT CTTTGGAGCT GAGTTTGCTT TGAGGATCTG GGCTGCAGGA 
TGTTGCTGTC GATACAAAGG CTGGCGTGGA CGGCTAAAGT TTGCCAGGAA GCCCCTGTGC 
ATGTTGGACA TCTTCGTACT GATTGCCTCT GTGCCAGTGG TTGCCGTGGG AAACCAGGGC 
AATGTCTTGG CCACCTCCCT GCGAAGCCTT CGCTTCCTGC AGATCCTGCG CATGCTTCGA 
ATGGATAGGA GGGGTGGCAC CTGGAAGCTC CTGGGCTCGG CTATCTGTGC CCACAGCAAA 
GAACTCATCA CTGCCTGGTA CATAGGCTTC CTGACACTCA TCCTTTCTTC ATTTCTTGTC 
TACCTGGTGG AGAAGGATGT GCCAGAGATG GATGCCCAAG GAGAGGAAAT GAAGGAGGAG 
TTTGAGACCT ATGCAGATGC TCTGTGGTGG GGCCTGATCA CACTGGCCAC CATTGGTTAT 
GGAGACAAGA CACCTAAAAC CTGGGAAGGA CGTCTGATTG CTGCCACCTT TTCTTTAATC 
GGCGTCTCCT TTTTTGCCCT TCCGGCAGGC ATCCTTGGCT CAGGACTGGC ACTGAAGGTT 
CAGGAGCAGC ACCGTCAGAA GCACTTTGAG AAGAGAAGGA AGCCAGCTGC GGAACTCATC 
CAGGCTGCCT GGAGATATTA TGCTACCAAC CCCAACAGGT TGGATCTGGT GGCAACCTGG 
AGATTTTATG AATCAGTTGT CTCTTTCCCA TTCTTCAGGA AAGAACAACT GGAAGCAGCA 
GCCAGCCAAA AGCTGGGTCT CTTGGATCGG GTTCGCCTTT CTAATCCTCG TGGTAGCAAT 
ACTAAAGGAA AGCTATTTAC CCCTCTGAAT GTAGATGCCA TAGAAGAAAG CCCTTCCAAA 
GAGCCAAAGC CTGTTGGCTT AAACAATAAA GAGCGTTTCC GCACCGCCTT CCGCATGAAA 
GCCTACGCTT TCTGGCAGAG TTCTGAAGAT GCTGGGACAG GCGACCCCAT GGCAGAAGAC 
AGGGGCTATG GGAATGACTT CCTCATTGAA GACATGATCC CTACCCTAAA GGCTGCCATC 
CGAGCTGTCA GAATTCTACA GTTCCGTCTA TATAAAAAAA AGTTCAAGGA GACGTTGAGG 
CCTTATGATG TGAAAGATGT GATTGAGCAG TATTCGGCCG GACATCTTGA CATGCTTTCC 
AGGATAAAGT ACCTACAGAC AAGAATAGAT ATGATTTTCA CCCCTGGACC TCCATCCACT 
CCAAAACATA AGAAGTCTCA GAAAGGGTCA GCATTTACCT ACCCATCCCA GCAGTCTCCA 
AGGAATGAAC CATATGTAGC CAGGGCAGCC ACATCAGAAA CTGAAGACCA AAGCATGATG 
GGGAAGTTTG TAAAAGTTGA AAGACAGGTT CATGACATGG GGAAGAAACT GGACTTCCTC 
GTGGACATGC ATATGCAGCA TATGGAACGC TTACAGGTAC ATGTCACTGA GTACTACCCA 
ACTAAGGGGG CCTCCTCCCC AGCCGAAGGG GAGAAGAAAG AAGACAACAG GTACTCTGAT 
TTGAAAACCA TCATCTGCAA CTACTCAGAG ACAGGGCCCC CTGACCCTCC TTACAGCTTC 
CACCAGGTGC CCATCGACAG AGTTGGCCCT TACGGGTTTT TTGCACATGA TCCTGTGAAA 
CTGACCCGAG GGGGACCCAG TTCTACAAAG GCTCAAGCTA ACCTTCCCTC CTCGGGAAGT 
ACATATGCAG AGAGGCCCAC AGTCCTGCCC ATCTTGACTC TTCTGGACTC ATGTGTGAGC 
TACCACTCCC AGACAGAACT GCAAGGTCCC TATTCGGACC ACATCTCGCC CCGCCAGAGA 
CGCAGCATCA CTAGGGACAG TGATACACCT CTGTCCCTCA TGTCCGTCAA TCACGAGGAA 
CTGGAGCGGT CTCCAAGTGG CTTCAGCATC TCACAAGACA GAGATGATTA TGTATTTGGC 
CCCAGTGGGG GATCGAGCTG GATGAGGGAA AAGCGGTACC TGGCTGAAGG AGAAACGGAC 
ACGGACACAG ACCCCTTCAC ACCCAGTGGT TCCATGCCTA TGTCATCCAC TGGGGATGGT 
ATTTCAGATT CCATATGGAC CCCTTCCAAC AAGCCCACTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Ubiquitin-specific Protease 36 (USP36) Controls Neuronal Precursor Cell-expressed Developmentally Down-regulated 4-2 (Nedd4-2) Actions over the Neurotrophin Receptor TrkA and Potassium Voltage-gated Channels 7.2/3 (Kv7.2/3).
The Journal of biological chemistry291(36)19132-45(2016 09)
Anta B,Mart?n-Rodr?guez C,Gomis-Perez C,Calvo L,L?pez-Benito S,Calder?n-Garc?a AA,Vicente-Garc?a C,Villarroel ?,Ar?valo JC

KCNQ channel openers reverse depressive symptoms via an active resilience mechanism.
Nature communications711671(2016 May)
Friedman AK,Juarez B,Ku SM,Zhang H,Calizo RC,Walsh JJ,Chaudhury D,Zhang S,Hawkins A,Dietz DM,Murrough JW,Ribadeneira M,Wong EH,Neve RL,Han MH

KCNQ Potassium Channels Modulate Sensitivity of Skin Down-hair (D-hair) Mechanoreceptors.
The Journal of biological chemistry291(11)5566-75(2016 Mar)
Sch?tze S,Orozco IJ,Jentsch TJ

The Voltage Activation of Cortical KCNQ Channels Depends on Global PIP2 Levels.
Biophysical journal110(5)1089-98(2016 Mar)
Kim KS,Duignan KM,Hawryluk JM,Soh H,Tzingounis AV

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Kcnq3 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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