KCNQ3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KCNQ3
Entrez Gene ID	3786
Full Name	potassium voltage-gated channel subfamily Q member 3
Synonyms	BFNC2,EBN2,KV7.3
General protein information	Preferred Names potassium voltage-gated channel subfamily Q member 3 Names potassium voltage-gated channel subfamily KQT member 3 potassium channel subunit alpha KvLQT3 potassium channel, voltage gated KQT-like subfamily Q, member 3 potassium channel, voltage-gated, subfamily Q, member 3 potassium voltage-gated channel, KQT-like subfamily, member 3 voltage-gated potassium channel subunit Kv7.3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 8 Map Location: 8q24.22
Summary	This gene encodes a protein that functions in the regulation of neuronal excitability. The encoded protein forms an M-channel by associating with the products of the related KCNQ2 or KCNQ5 genes, which both encode integral membrane proteins. M-channel currents are inhibited by M1 muscarinic acetylcholine receptors and are activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014].
Disorder MIM:	602232
Disorder Html:	Seizures, benign neonatal, type 2, 121201 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_017013400.1	XP_016868889.1	potassium voltage-gated channel subfamily KQT member 3 isoform X1
XM_006716555.3	XP_006716618.1	potassium voltage-gated channel subfamily KQT member 3 isoform X3
NM_004519.4	NP_004510.1	potassium voltage-gated channel subfamily KQT member 3 isoform 1
NM_001204824.1	NP_001191753.1	potassium voltage-gated channel subfamily KQT member 3 isoform 2 precursor
NM_004519.3	NP_004510.1	potassium voltage-gated channel subfamily KQT member 3 isoform 1
XM_011517026.2	XP_011515328.1	potassium voltage-gated channel subfamily KQT member 3 isoform X2
XM_005250914.3	XP_005250971.1	potassium voltage-gated channel subfamily KQT member 3 isoform X4

Pathways from BioSystems

Homologies

	KCNQ3	XP_001089122.1
Xenopus tropicalis (tropical clawed frog)	kcnq3	XP_004915103.1
Canis lupus familiaris (dog)	KCNQ3	XP_532334.3
Gallus gallus (chicken)	KCNQ3	XP_003640915.2
Danio rerio (zebrafish)	kcnq3	XP_003197981.1
Bos taurus (cattle)	KCNQ3	NP_776799.1
Homo sapiens (human)	KCNQ3	NP_004510.1
Pan troglodytes (chimpanzee)	KCNQ3	XP_519963.2
Mus musculus (house mouse)	Kcnq3	NP_690887.2
Rattus norvegicus (Norway rat)	Kcnq3	NP_113785.3

Gene Ontology
Bibliography

Related articles in PubMed

Pharmacophore modeling, 3D-QSAR, and in silico ADME prediction of N-pyridyl and pyrimidine benzamides as potent antiepileptic agents.
Malik R, Mehta P, Srivastava S, Choudhary BS, Sharma M
Journal of receptor and signal transduction research37(3)259-266(2017 Jun)

Structural Insights into the M-Channel Proximal C-Terminus/Calmodulin Complex.
Strulovich R, Tobelaim WS, Attali B, Hirsch JA
Biochemistry55(38)5353-65(2016 09)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In the present work, a pharmacophore-based 3D-QSAR model was generated for a series of N-pyridyl and pyrimidine benzamides possessing KCNQ2/Q3 opening activity. The pharmacophore model generated contains one hydrogen bond donor (D), one hydrophobic (H), and two aromatic rings (R). They are the crucial molecular write-up detailing predicted binding efficacy of high affinity and low affinity ligands for KCNQ2/Q3 opening a
Title: Pharmacophore modeling, 3D-QSAR, and in silico ADME prediction of N-pyridyl and pyrimidine benzamides as potent antiepileptic agents.

USP36 actions extend beyond TrkA because the presence of USP36 interferes with Nedd4-2-dependent Kv7.2/3 channel regulation.
Title: Ubiquitin-specific Protease 36 (USP36) Controls Neuronal Precursor Cell-expressed Developmentally Down-regulated 4-2 (Nedd4-2) Actions over the Neurotrophin Receptor TrkA and Potassium Voltage-gated Channels 7.2/3 (Kv7.2/3).

Tannic acid activates Kv7.4 and Kv7.3/7.5 K(+) channels resulting in vasodilation.
Title: Tannic acid activates the Kv7.4 and Kv7.3/7.5 K(+) channels expressed in HEK293 cells and reduces tension in the rat mesenteric arteries.

a structural mechanism for the gating of the Kv7.3 PM and for the site of action of RTG as a Kv7.2/Kv7.3 K(+) current activator.
Title: The Sensorless Pore Module of Voltage-gated K+ Channel Family 7 Embodies the Target Site for the Anticonvulsant Retigabine.

Carboxyl terminus helix C-D linker residues play a role in KCNQ3 current amplitudes by controlling the exit of the KCNQ3 channel from the endoplasmic reticulum.
Title: The Role of the Carboxyl Terminus Helix C-D Linker in Regulating KCNQ3 K+ Current Amplitudes by Controlling Channel Trafficking.

The following KCNQ3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KCNQ3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu24527	NM_004519.4 Latest version!	Homo sapiens potassium voltage-gated channel subfamily Q member 3 (KCNQ3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$439.50-$615.30 $879.00
OHu42445	XM_006716555.3 Latest version!	Homo sapiens potassium voltage-gated channel subfamily Q member 3 (KCNQ3), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu42446	XM_005250914.3 Latest version!	Homo sapiens potassium voltage-gated channel subfamily Q member 3 (KCNQ3), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu24538	NM_001204824.1 Latest version!	Homo sapiens potassium voltage-gated channel subfamily Q member 3 (KCNQ3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu58600	XM_011517026.2 Latest version!	Homo sapiens potassium voltage-gated channel subfamily Q member 3 (KCNQ3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu97962	XM_017013400.1 Latest version!	Homo sapiens potassium voltage-gated channel subfamily Q member 3 (KCNQ3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
View Old Accession Versions >>
OHu24527	NM_004519.3	Homo sapiens potassium voltage-gated channel subfamily Q member 3 (KCNQ3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$439.50-$615.30 $879.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KCNQ3 ( NM_004519.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_004510.1 Homo sapiens potassium voltage-gated channel subfamily Q member 3 (KCNQ3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu24527
Clone ID Related Accession (Same CDS sequence)	NM_004519.4 , NM_004519.3
Accession Version	NM_004519.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2619bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	potassium voltage-gated channel subfamily KQT member 3 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC018540.13, AF033347.1, AV728013.1, AC131042.6 and BX538233.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_004519.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). The 5' extent of this variant is inferred based on orthologous alignments. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.190413.1, SRR1660807.94543.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1966682, SAMEA1968189 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000388996.10/ ENSP00000373648.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGGCTCA AGGCGCGCAG GGCGGCGGGG GCGGCTGGCG GCGGCGGCGA CGGGGGCGGC 
GGAGGCGGCG GGGCGGCTAA CCCAGCCGGA GGGGACGCGG CGGCGGCCGG CGACGAGGAG 
CGGAAAGTGG GGCTGGCGCC CGGCGACGTG GAGCAAGTCA CCTTGGCGCT CGGGGCCGGA 
GCCGACAAAG ACGGGACCCT GCTGCTGGAG GGCGGCGGCC GCGACGAGGG GCAGCGGAGG 
ACCCCGCAGG GCATCGGGCT CCTGGCCAAG ACCCCGCTGA GCCGCCCAGT CAAGAGAAAC 
AACGCCAAGT ACCGGCGCAT CCAAACTTTG ATCTACGACG CCCTGGAGAG ACCGCGGGGC 
TGGGCGCTGC TTTACCACGC GTTGGTGTTC CTGATTGTCC TGGGGTGCTT GATTCTGGCT 
GTCCTGACCA CATTCAAGGA GTATGAGACT GTCTCGGGAG ACTGGCTTCT GTTACTGGAG 
ACATTTGCTA TTTTCATCTT TGGAGCCGAG TTTGCTTTGA GGATCTGGGC TGCTGGATGT 
TGCTGCCGAT ACAAAGGCTG GCGGGGCCGA CTGAAGTTTG CCAGGAAGCC CCTGTGCATG 
TTGGACATCT TTGTGCTGAT TGCCTCTGTG CCAGTGGTTG CTGTGGGAAA CCAAGGCAAT 
GTTCTGGCCA CCTCCCTGCG AAGCCTGCGC TTCCTGCAGA TCCTGCGCAT GCTGCGGATG 
GACCGGAGAG GTGGCACCTG GAAGCTTCTG GGCTCAGCCA TCTGTGCCCA CAGCAAAGAA 
CTCATCACGG CCTGGTACAT CGGTTTCCTG ACACTCATCC TTTCTTCATT TCTTGTCTAC 
CTGGTTGAGA AAGACGTCCC AGAGGTGGAT GCACAAGGAG AGGAGATGAA AGAGGAGTTT 
GAGACCTATG CAGATGCCCT GTGGTGGGGC CTGATCACAC TGGCCACCAT TGGCTATGGA 
GACAAGACAC CCAAAACGTG GGAAGGCCGT CTGATTGCCG CCACCTTTTC CTTAATTGGC 
GTCTCCTTTT TTGCCCTTCC AGCGGGCATC CTGGGGTCCG GGCTGGCCCT CAAGGTGCAG 
GAGCAACACC GTCAGAAGCA CTTTGAGAAA AGGAGGAAGC CAGCTGCTGA GCTCATTCAG 
GCTGCCTGGA GGTATTATGC TACCAACCCC AACAGGATTG ACCTGGTGGC GACATGGAGA 
TTTTATGAAT CAGTCGTCTC TTTTCCTTTC TTCAGGAAAG AACAGCTGGA GGCAGCATCC 
AGCCAAAAGC TGGGTCTCTT GGATCGGGTT CGCCTTTCTA ATCCTCGTGG TAGCAATACT 
AAAGGAAAGC TATTTACCCC TCTGAATGTA GATGCCATAG AAGAAAGTCC TTCTAAAGAA 
CCAAAGCCTG TTGGCTTAAA CAATAAAGAG CGTTTCCGCA CGGCCTTCCG CATGAAAGCC 
TACGCTTTCT GGCAGAGTTC TGAAGATGCC GGGACAGGTG ACCCCATGGC GGAAGACAGG 
GGCTATGGGA ATGACTTCCC CATCGAAGAC ATGATCCCCA CCCTGAAGGC CGCCATCCGA 
GCCGTCAGAA TTCTACAATT CCGTCTCTAT AAAAAAAAAT TCAAGGAGAC TTTGAGGCCT 
TACGATGTGA AGGATGTGAT TGAGCAGTAT TCTGCCGGGC ATCTCGACAT GCTTTCCAGG 
ATAAAGTACC TTCAGACGAG AATAGATATG ATTTTCACCC CTGGACCTCC CTCCACGCCA 
AAACACAAGA AGTCTCAGAA AGGGTCAGCA TTCACCTTCC CATCCCAGCA ATCTCCCAGG 
AATGAACCAT ATGTAGCCAG ACCATCCACA TCAGAAATCG AAGACCAAAG CATGATGGGG 
AAGTTTGTAA AAGTTGAAAG ACAGGTTCAG GACATGGGGA AGAAGCTGGA CTTCCTCGTG 
GATATGCACA TGCAACACAT GGAACGGTTG CAGGTGCAGG TCACGGAGTA TTACCCAACC 
AAGGGCACCT CCTCGCCAGC TGAAGCAGAG AAGAAGGAGG ACAACAGGTA TTCCGATTTG 
AAAACCATCA TCTGCAACTA TTCTGAGACA GGCCCCCCGG AACCACCCTA CAGCTTCCAC 
CAGGTGACCA TTGACAAAGT CAGCCCCTAT GGGTTTTTTG CACATGACCC TGTGAACCTG 
CCCCGAGGGG GACCCAGTTC TGGAAAGGTT CAGGCAACTC CTCCTTCCTC AGCAACAACG 
TATGTGGAGA GGCCCACGGT CCTGCCTATC TTGACTCTTC TCGACTCCCG AGTGAGCTGC 
CACTCCCAGG CTGACCTGCA GGGCCCCTAC TCGGACCGAA TCTCCCCCCG GCAGAGACGT 
AGCATCACGC GAGACAGTGA CACACCTCTG TCCCTGATGT CGGTCAACCA CGAGGAGCTG 
GAGAGGTCTC CAAGTGGCTT CAGCATCTCC CAGGACAGAG ATGATTATGT GTTCGGCCCC 
AATGGGGGGT CGAGCTGGAT GAGGGAGAAG CGGTACCTCG CCGAGGGTGA GACGGACACA 
GACACGGACC CCTTCACGCC CAGCGGCTCC ATGCCTCTGT CGTCCACAGG GGATGGGATT 
TCTGATTCAG TATGGACCCC TTCCAATAAG CCCATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004510.1
CDS	564..3182
Translation	MGLKARRAAGAAGGGGDGGGGGGGAANPAGGDAAAAGDEERKVGLAPGDVEQVTLALGAGADKDGTLLLEGGGRDEGQRRTPQGIGLLAKTPLSRPVKRNNAKYRRIQTLIYDALERPRGWALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWRFYESVVSFPFFRKEQLEAASSQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTGDPMAEDRGYGNDFPIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTFPSQQSPRNEPYVARPSTSEIEDQSMMGKFVKVERQVQDMGKKLDFLVDMHMQHMERLQVQVTEYYPTKGTSSPAEAEKKEDNRYSDLKTIICNYSETGPPEPPYSFHQVTIDKVSPYGFFAHDPVNLPRGGPSSGKVQATPPSSATTYVERPTVLPILTLLDSRVSCHSQADLQGPYSDRISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPNGGSSWMREKRYLAEGETDTDTDPFTPSGSMPLSSTGDGISDSVWTPSNKPI

Target ORF information:

RefSeq Version	NM_004519.4
Organism	Homo sapiens(human)
Definition	Homo sapiens potassium voltage-gated channel subfamily Q member 3 (KCNQ3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004519.4

ORF Insert Sequence:

ATGGGGCTCA AGGCGCGCAG GGCGGCGGGG GCGGCTGGCG GCGGCGGCGA CGGGGGCGGC 
GGAGGCGGCG GGGCGGCTAA CCCAGCCGGA GGGGACGCGG CGGCGGCCGG CGACGAGGAG 
CGGAAAGTGG GGCTGGCGCC CGGCGACGTG GAGCAAGTCA CCTTGGCGCT CGGGGCCGGA 
GCCGACAAAG ACGGGACCCT GCTGCTGGAG GGCGGCGGCC GCGACGAGGG GCAGCGGAGG 
ACCCCGCAGG GCATCGGGCT CCTGGCCAAG ACCCCGCTGA GCCGCCCAGT CAAGAGAAAC 
AACGCCAAGT ACCGGCGCAT CCAAACTTTG ATCTACGACG CCCTGGAGAG ACCGCGGGGC 
TGGGCGCTGC TTTACCACGC GTTGGTGTTC CTGATTGTCC TGGGGTGCTT GATTCTGGCT 
GTCCTGACCA CATTCAAGGA GTATGAGACT GTCTCGGGAG ACTGGCTTCT GTTACTGGAG 
ACATTTGCTA TTTTCATCTT TGGAGCCGAG TTTGCTTTGA GGATCTGGGC TGCTGGATGT 
TGCTGCCGAT ACAAAGGCTG GCGGGGCCGA CTGAAGTTTG CCAGGAAGCC CCTGTGCATG 
TTGGACATCT TTGTGCTGAT TGCCTCTGTG CCAGTGGTTG CTGTGGGAAA CCAAGGCAAT 
GTTCTGGCCA CCTCCCTGCG AAGCCTGCGC TTCCTGCAGA TCCTGCGCAT GCTGCGGATG 
GACCGGAGAG GTGGCACCTG GAAGCTTCTG GGCTCAGCCA TCTGTGCCCA CAGCAAAGAA 
CTCATCACGG CCTGGTACAT CGGTTTCCTG ACACTCATCC TTTCTTCATT TCTTGTCTAC 
CTGGTTGAGA AAGACGTCCC AGAGGTGGAT GCACAAGGAG AGGAGATGAA AGAGGAGTTT 
GAGACCTATG CAGATGCCCT GTGGTGGGGC CTGATCACAC TGGCCACCAT TGGCTATGGA 
GACAAGACAC CCAAAACGTG GGAAGGCCGT CTGATTGCCG CCACCTTTTC CTTAATTGGC 
GTCTCCTTTT TTGCCCTTCC AGCGGGCATC CTGGGGTCCG GGCTGGCCCT CAAGGTGCAG 
GAGCAACACC GTCAGAAGCA CTTTGAGAAA AGGAGGAAGC CAGCTGCTGA GCTCATTCAG 
GCTGCCTGGA GGTATTATGC TACCAACCCC AACAGGATTG ACCTGGTGGC GACATGGAGA 
TTTTATGAAT CAGTCGTCTC TTTTCCTTTC TTCAGGAAAG AACAGCTGGA GGCAGCATCC 
AGCCAAAAGC TGGGTCTCTT GGATCGGGTT CGCCTTTCTA ATCCTCGTGG TAGCAATACT 
AAAGGAAAGC TATTTACCCC TCTGAATGTA GATGCCATAG AAGAAAGTCC TTCTAAAGAA 
CCAAAGCCTG TTGGCTTAAA CAATAAAGAG CGTTTCCGCA CGGCCTTCCG CATGAAAGCC 
TACGCTTTCT GGCAGAGTTC TGAAGATGCC GGGACAGGTG ACCCCATGGC GGAAGACAGG 
GGCTATGGGA ATGACTTCCC CATCGAAGAC ATGATCCCCA CCCTGAAGGC CGCCATCCGA 
GCCGTCAGAA TTCTACAATT CCGTCTCTAT AAAAAAAAAT TCAAGGAGAC TTTGAGGCCT 
TACGATGTGA AGGATGTGAT TGAGCAGTAT TCTGCCGGGC ATCTCGACAT GCTTTCCAGG 
ATAAAGTACC TTCAGACGAG AATAGATATG ATTTTCACCC CTGGACCTCC CTCCACGCCA 
AAACACAAGA AGTCTCAGAA AGGGTCAGCA TTCACCTTCC CATCCCAGCA ATCTCCCAGG 
AATGAACCAT ATGTAGCCAG ACCATCCACA TCAGAAATCG AAGACCAAAG CATGATGGGG 
AAGTTTGTAA AAGTTGAAAG ACAGGTTCAG GACATGGGGA AGAAGCTGGA CTTCCTCGTG 
GATATGCACA TGCAACACAT GGAACGGTTG CAGGTGCAGG TCACGGAGTA TTACCCAACC 
AAGGGCACCT CCTCGCCAGC TGAAGCAGAG AAGAAGGAGG ACAACAGGTA TTCCGATTTG 
AAAACCATCA TCTGCAACTA TTCTGAGACA GGCCCCCCGG AACCACCCTA CAGCTTCCAC 
CAGGTGACCA TTGACAAAGT CAGCCCCTAT GGGTTTTTTG CACATGACCC TGTGAACCTG 
CCCCGAGGGG GACCCAGTTC TGGAAAGGTT CAGGCAACTC CTCCTTCCTC AGCAACAACG 
TATGTGGAGA GGCCCACGGT CCTGCCTATC TTGACTCTTC TCGACTCCCG AGTGAGCTGC 
CACTCCCAGG CTGACCTGCA GGGCCCCTAC TCGGACCGAA TCTCCCCCCG GCAGAGACGT 
AGCATCACGC GAGACAGTGA CACACCTCTG TCCCTGATGT CGGTCAACCA CGAGGAGCTG 
GAGAGGTCTC CAAGTGGCTT CAGCATCTCC CAGGACAGAG ATGATTATGT GTTCGGCCCC 
AATGGGGGGT CGAGCTGGAT GAGGGAGAAG CGGTACCTCG CCGAGGGTGA GACGGACACA 
GACACGGACC CCTTCACGCC CAGCGGCTCC ATGCCTCTGT CGTCCACAGG GGATGGGATT 
TCTGATTCAG TATGGACCCC TTCCAATAAG CCCATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KCNQ3 ( NM_004519.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004510.1 Homo sapiens potassium voltage-gated channel subfamily Q member 3 (KCNQ3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu24527
Clone ID Related Accession (Same CDS sequence)	NM_004519.4 , NM_004519.3
Accession Version	NM_004519.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2619bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	potassium voltage-gated channel subfamily KQT member 3 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC018540.13, AF033347.1, AV728013.1, AC131042.6 and BX538233.1. This sequence is a reference standard in the RefSeqGene project. On Mar 10, 2011 this sequence version replaced NM_004519.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). The 5' extent of this variant is inferred based on orthologous alignments. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.190413.1, SRR1660807.94543.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1966682, SAMEA1968189 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGCTCA AGGCGCGCAG GGCGGCGGGG GCGGCTGGCG GCGGCGGCGA CGGGGGCGGC 
GGAGGCGGCG GGGCGGCTAA CCCAGCCGGA GGGGACGCGG CGGCGGCCGG CGACGAGGAG 
CGGAAAGTGG GGCTGGCGCC CGGCGACGTG GAGCAAGTCA CCTTGGCGCT CGGGGCCGGA 
GCCGACAAAG ACGGGACCCT GCTGCTGGAG GGCGGCGGCC GCGACGAGGG GCAGCGGAGG 
ACCCCGCAGG GCATCGGGCT CCTGGCCAAG ACCCCGCTGA GCCGCCCAGT CAAGAGAAAC 
AACGCCAAGT ACCGGCGCAT CCAAACTTTG ATCTACGACG CCCTGGAGAG ACCGCGGGGC 
TGGGCGCTGC TTTACCACGC GTTGGTGTTC CTGATTGTCC TGGGGTGCTT GATTCTGGCT 
GTCCTGACCA CATTCAAGGA GTATGAGACT GTCTCGGGAG ACTGGCTTCT GTTACTGGAG 
ACATTTGCTA TTTTCATCTT TGGAGCCGAG TTTGCTTTGA GGATCTGGGC TGCTGGATGT 
TGCTGCCGAT ACAAAGGCTG GCGGGGCCGA CTGAAGTTTG CCAGGAAGCC CCTGTGCATG 
TTGGACATCT TTGTGCTGAT TGCCTCTGTG CCAGTGGTTG CTGTGGGAAA CCAAGGCAAT 
GTTCTGGCCA CCTCCCTGCG AAGCCTGCGC TTCCTGCAGA TCCTGCGCAT GCTGCGGATG 
GACCGGAGAG GTGGCACCTG GAAGCTTCTG GGCTCAGCCA TCTGTGCCCA CAGCAAAGAA 
CTCATCACGG CCTGGTACAT CGGTTTCCTG ACACTCATCC TTTCTTCATT TCTTGTCTAC 
CTGGTTGAGA AAGACGTCCC AGAGGTGGAT GCACAAGGAG AGGAGATGAA AGAGGAGTTT 
GAGACCTATG CAGATGCCCT GTGGTGGGGC CTGATCACAC TGGCCACCAT TGGCTATGGA 
GACAAGACAC CCAAAACGTG GGAAGGCCGT CTGATTGCCG CCACCTTTTC CTTAATTGGC 
GTCTCCTTTT TTGCCCTTCC AGCGGGCATC CTGGGGTCCG GGCTGGCCCT CAAGGTGCAG 
GAGCAACACC GTCAGAAGCA CTTTGAGAAA AGGAGGAAGC CAGCTGCTGA GCTCATTCAG 
GCTGCCTGGA GGTATTATGC TACCAACCCC AACAGGATTG ACCTGGTGGC GACATGGAGA 
TTTTATGAAT CAGTCGTCTC TTTTCCTTTC TTCAGGAAAG AACAGCTGGA GGCAGCATCC 
AGCCAAAAGC TGGGTCTCTT GGATCGGGTT CGCCTTTCTA ATCCTCGTGG TAGCAATACT 
AAAGGAAAGC TATTTACCCC TCTGAATGTA GATGCCATAG AAGAAAGTCC TTCTAAAGAA 
CCAAAGCCTG TTGGCTTAAA CAATAAAGAG CGTTTCCGCA CGGCCTTCCG CATGAAAGCC 
TACGCTTTCT GGCAGAGTTC TGAAGATGCC GGGACAGGTG ACCCCATGGC GGAAGACAGG 
GGCTATGGGA ATGACTTCCC CATCGAAGAC ATGATCCCCA CCCTGAAGGC CGCCATCCGA 
GCCGTCAGAA TTCTACAATT CCGTCTCTAT AAAAAAAAAT TCAAGGAGAC TTTGAGGCCT 
TACGATGTGA AGGATGTGAT TGAGCAGTAT TCTGCCGGGC ATCTCGACAT GCTTTCCAGG 
ATAAAGTACC TTCAGACGAG AATAGATATG ATTTTCACCC CTGGACCTCC CTCCACGCCA 
AAACACAAGA AGTCTCAGAA AGGGTCAGCA TTCACCTTCC CATCCCAGCA ATCTCCCAGG 
AATGAACCAT ATGTAGCCAG ACCATCCACA TCAGAAATCG AAGACCAAAG CATGATGGGG 
AAGTTTGTAA AAGTTGAAAG ACAGGTTCAG GACATGGGGA AGAAGCTGGA CTTCCTCGTG 
GATATGCACA TGCAACACAT GGAACGGTTG CAGGTGCAGG TCACGGAGTA TTACCCAACC 
AAGGGCACCT CCTCGCCAGC TGAAGCAGAG AAGAAGGAGG ACAACAGGTA TTCCGATTTG 
AAAACCATCA TCTGCAACTA TTCTGAGACA GGCCCCCCGG AACCACCCTA CAGCTTCCAC 
CAGGTGACCA TTGACAAAGT CAGCCCCTAT GGGTTTTTTG CACATGACCC TGTGAACCTG 
CCCCGAGGGG GACCCAGTTC TGGAAAGGTT CAGGCAACTC CTCCTTCCTC AGCAACAACG 
TATGTGGAGA GGCCCACGGT CCTGCCTATC TTGACTCTTC TCGACTCCCG AGTGAGCTGC 
CACTCCCAGG CTGACCTGCA GGGCCCCTAC TCGGACCGAA TCTCCCCCCG GCAGAGACGT 
AGCATCACGC GAGACAGTGA CACACCTCTG TCCCTGATGT CGGTCAACCA CGAGGAGCTG 
GAGAGGTCTC CAAGTGGCTT CAGCATCTCC CAGGACAGAG ATGATTATGT GTTCGGCCCC 
AATGGGGGGT CGAGCTGGAT GAGGGAGAAG CGGTACCTCG CCGAGGGTGA GACGGACACA 
GACACGGACC CCTTCACGCC CAGCGGCTCC ATGCCTCTGT CGTCCACAGG GGATGGGATT 
TCTGATTCAG TATGGACCCC TTCCAATAAG CCCATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004510.1
CDS	226..2844
Translation	MGLKARRAAGAAGGGGDGGGGGGGAANPAGGDAAAAGDEERKVGLAPGDVEQVTLALGAGADKDGTLLLEGGGRDEGQRRTPQGIGLLAKTPLSRPVKRNNAKYRRIQTLIYDALERPRGWALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWRFYESVVSFPFFRKEQLEAASSQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTGDPMAEDRGYGNDFPIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTFPSQQSPRNEPYVARPSTSEIEDQSMMGKFVKVERQVQDMGKKLDFLVDMHMQHMERLQVQVTEYYPTKGTSSPAEAEKKEDNRYSDLKTIICNYSETGPPEPPYSFHQVTIDKVSPYGFFAHDPVNLPRGGPSSGKVQATPPSSATTYVERPTVLPILTLLDSRVSCHSQADLQGPYSDRISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPNGGSSWMREKRYLAEGETDTDTDPFTPSGSMPLSSTGDGISDSVWTPSNKPI

Target ORF information:

RefSeq Version	NM_004519.3
Organism	Homo sapiens(human)
Definition	Homo sapiens potassium voltage-gated channel subfamily Q member 3 (KCNQ3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004519.3

ORF Insert Sequence:

ATGGGGCTCA AGGCGCGCAG GGCGGCGGGG GCGGCTGGCG GCGGCGGCGA CGGGGGCGGC 
GGAGGCGGCG GGGCGGCTAA CCCAGCCGGA GGGGACGCGG CGGCGGCCGG CGACGAGGAG 
CGGAAAGTGG GGCTGGCGCC CGGCGACGTG GAGCAAGTCA CCTTGGCGCT CGGGGCCGGA 
GCCGACAAAG ACGGGACCCT GCTGCTGGAG GGCGGCGGCC GCGACGAGGG GCAGCGGAGG 
ACCCCGCAGG GCATCGGGCT CCTGGCCAAG ACCCCGCTGA GCCGCCCAGT CAAGAGAAAC 
AACGCCAAGT ACCGGCGCAT CCAAACTTTG ATCTACGACG CCCTGGAGAG ACCGCGGGGC 
TGGGCGCTGC TTTACCACGC GTTGGTGTTC CTGATTGTCC TGGGGTGCTT GATTCTGGCT 
GTCCTGACCA CATTCAAGGA GTATGAGACT GTCTCGGGAG ACTGGCTTCT GTTACTGGAG 
ACATTTGCTA TTTTCATCTT TGGAGCCGAG TTTGCTTTGA GGATCTGGGC TGCTGGATGT 
TGCTGCCGAT ACAAAGGCTG GCGGGGCCGA CTGAAGTTTG CCAGGAAGCC CCTGTGCATG 
TTGGACATCT TTGTGCTGAT TGCCTCTGTG CCAGTGGTTG CTGTGGGAAA CCAAGGCAAT 
GTTCTGGCCA CCTCCCTGCG AAGCCTGCGC TTCCTGCAGA TCCTGCGCAT GCTGCGGATG 
GACCGGAGAG GTGGCACCTG GAAGCTTCTG GGCTCAGCCA TCTGTGCCCA CAGCAAAGAA 
CTCATCACGG CCTGGTACAT CGGTTTCCTG ACACTCATCC TTTCTTCATT TCTTGTCTAC 
CTGGTTGAGA AAGACGTCCC AGAGGTGGAT GCACAAGGAG AGGAGATGAA AGAGGAGTTT 
GAGACCTATG CAGATGCCCT GTGGTGGGGC CTGATCACAC TGGCCACCAT TGGCTATGGA 
GACAAGACAC CCAAAACGTG GGAAGGCCGT CTGATTGCCG CCACCTTTTC CTTAATTGGC 
GTCTCCTTTT TTGCCCTTCC AGCGGGCATC CTGGGGTCCG GGCTGGCCCT CAAGGTGCAG 
GAGCAACACC GTCAGAAGCA CTTTGAGAAA AGGAGGAAGC CAGCTGCTGA GCTCATTCAG 
GCTGCCTGGA GGTATTATGC TACCAACCCC AACAGGATTG ACCTGGTGGC GACATGGAGA 
TTTTATGAAT CAGTCGTCTC TTTTCCTTTC TTCAGGAAAG AACAGCTGGA GGCAGCATCC 
AGCCAAAAGC TGGGTCTCTT GGATCGGGTT CGCCTTTCTA ATCCTCGTGG TAGCAATACT 
AAAGGAAAGC TATTTACCCC TCTGAATGTA GATGCCATAG AAGAAAGTCC TTCTAAAGAA 
CCAAAGCCTG TTGGCTTAAA CAATAAAGAG CGTTTCCGCA CGGCCTTCCG CATGAAAGCC 
TACGCTTTCT GGCAGAGTTC TGAAGATGCC GGGACAGGTG ACCCCATGGC GGAAGACAGG 
GGCTATGGGA ATGACTTCCC CATCGAAGAC ATGATCCCCA CCCTGAAGGC CGCCATCCGA 
GCCGTCAGAA TTCTACAATT CCGTCTCTAT AAAAAAAAAT TCAAGGAGAC TTTGAGGCCT 
TACGATGTGA AGGATGTGAT TGAGCAGTAT TCTGCCGGGC ATCTCGACAT GCTTTCCAGG 
ATAAAGTACC TTCAGACGAG AATAGATATG ATTTTCACCC CTGGACCTCC CTCCACGCCA 
AAACACAAGA AGTCTCAGAA AGGGTCAGCA TTCACCTTCC CATCCCAGCA ATCTCCCAGG 
AATGAACCAT ATGTAGCCAG ACCATCCACA TCAGAAATCG AAGACCAAAG CATGATGGGG 
AAGTTTGTAA AAGTTGAAAG ACAGGTTCAG GACATGGGGA AGAAGCTGGA CTTCCTCGTG 
GATATGCACA TGCAACACAT GGAACGGTTG CAGGTGCAGG TCACGGAGTA TTACCCAACC 
AAGGGCACCT CCTCGCCAGC TGAAGCAGAG AAGAAGGAGG ACAACAGGTA TTCCGATTTG 
AAAACCATCA TCTGCAACTA TTCTGAGACA GGCCCCCCGG AACCACCCTA CAGCTTCCAC 
CAGGTGACCA TTGACAAAGT CAGCCCCTAT GGGTTTTTTG CACATGACCC TGTGAACCTG 
CCCCGAGGGG GACCCAGTTC TGGAAAGGTT CAGGCAACTC CTCCTTCCTC AGCAACAACG 
TATGTGGAGA GGCCCACGGT CCTGCCTATC TTGACTCTTC TCGACTCCCG AGTGAGCTGC 
CACTCCCAGG CTGACCTGCA GGGCCCCTAC TCGGACCGAA TCTCCCCCCG GCAGAGACGT 
AGCATCACGC GAGACAGTGA CACACCTCTG TCCCTGATGT CGGTCAACCA CGAGGAGCTG 
GAGAGGTCTC CAAGTGGCTT CAGCATCTCC CAGGACAGAG ATGATTATGT GTTCGGCCCC 
AATGGGGGGT CGAGCTGGAT GAGGGAGAAG CGGTACCTCG CCGAGGGTGA GACGGACACA 
GACACGGACC CCTTCACGCC CAGCGGCTCC ATGCCTCTGT CGTCCACAGG GGATGGGATT 
TCTGATTCAG TATGGACCCC TTCCAATAAG CCCATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KCNQ3 ( XM_006716555.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006716618.1 Homo sapiens potassium voltage-gated channel subfamily Q member 3 (KCNQ3), transcript variant X3, mRNA.

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CloneID	OHu42445
Clone ID Related Accession (Same CDS sequence)	XM_006716555.3
Accession Version	XM_006716555.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1911bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	potassium voltage-gated channel subfamily KQT member 3 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006716555.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGCGGA TGGACCGGAG AGGTGGCACC TGGAAGCTTC TGGGCTCAGC CATCTGTGCC 
CACAGCAAAG AACTCATCAC GGCCTGGTAC ATCGGTTTCC TGACACTCAT CCTTTCTTCA 
TTTCTTGTCT ACCTGGTTGA GAAAGACGTC CCAGAGGTGG ATGCACAAGG AGAGGAGATG 
AAAGAGGAGT TTGAGACCTA TGCAGATGCC CTGTGGTGGG GCCTGATCAC ACTGGCCACC 
ATTGGCTATG GAGACAAGAC ACCCAAAACG TGGGAAGGCC GTCTGATTGC CGCCACCTTT 
TCCTTAATTG GCGTCTCCTT TTTTGCCCTT CCAGCGGGCA TCCTGGGGTC CGGGCTGGCC 
CTCAAGGTGC AGGAGCAACA CCGTCAGAAG CACTTTGAGA AAAGGAGGAA GCCAGCTGCT 
GAGCTCATTC AGGCTGCCTG GAGGTATTAT GCTACCAACC CCAACAGGAT TGACCTGGTG 
GCGACATGGA GATTTTATGA ATCAGTCGTC TCTTTTCCTT TCTTCAGGAA AGAACAGCTG 
GAGGCAGCAT CCAGCCAAAA GCTGGGTCTC TTGGATCGGG TTCGCCTTTC TAATCCTCGT 
GGTAGCAATA CTAAAGGAAA GCTATTTACC CCTCTGAATG TAGATGCCAT AGAAGAAAGT 
CCTTCTAAAG AACCAAAGCC TGTTGGCTTA AACAATAAAG AGCGTTTCCG CACGGCCTTC 
CGCATGAAAG CCTACGCTTT CTGGCAGAGT TCTGAAGATG CCGGGACAGG TGACCCCATG 
GCGGAAGACA GGGGCTATGG GAATGACTTC CCCATCGAAG ACATGATCCC CACCCTGAAG 
GCCGCCATCC GAGCCGTCAG AATTCTACAA TTCCGTCTCT ATAAAAAAAA ATTCAAGGAG 
ACTTTGAGGC CTTACGATGT GAAGGATGTG ATTGAGCAGT ATTCTGCCGG GCATCTCGAC 
ATGCTTTCCA GGATAAAGTA CCTTCAGACG AGAATAGATA TGATTTTCAC CCCTGGACCT 
CCCTCCACGC CAAAACACAA GAAGTCTCAG AAAGGGTCAG CATTCACCTT CCCATCCCAG 
CAATCTCCCA GGAATGAACC ATATGTAGCC AGACCATCCA CATCAGAAAT CGAAGACCAA 
AGCATGATGG GGAAGTTTGT AAAAGTTGAA AGACAGGTTC AGGACATGGG GAAGAAGCTG 
GACTTCCTCG TGGATATGCA CATGCAACAC ATGGAACGGT TGCAGGTGCA GGTCACGGAG 
TATTACCCAA CCAAGGGCAC CTCCTCGCCA GCTGAAGCAG AGAAGAAGGA GGACAACAGG 
TATTCCGATT TGAAAACCAT CATCTGCAAC TATTCTGAGA CAGGCCCCCC GGAACCACCC 
TACAGCTTCC ACCAGGTGAC CATTGACAAA GTCAGCCCCT ATGGGTTTTT TGCACATGAC 
CCTGTGAACC TGCCCCGAGG GGGACCCAGT TCTGGAAAGG TTCAGGCAAC TCCTCCTTCC 
TCAGCAACAA CGTATGTGGA GAGGCCCACG GTCCTGCCTA TCTTGACTCT TCTCGACTCC 
CGAGTGAGCT GCCACTCCCA GGCTGACCTG CAGGGCCCCT ACTCGGACCG AATCTCCCCC 
CGGCAGAGAC GTAGCATCAC GCGAGACAGT GACACACCTC TGTCCCTGAT GTCGGTCAAC 
CACGAGGAGC TGGAGAGGTC TCCAAGTGGC TTCAGCATCT CCCAGGACAG AGATGATTAT 
GTGTTCGGCC CCAATGGGGG GTCGAGCTGG ATGAGGGAGA AGCGGTACCT CGCCGAGGGT 
GAGACGGACA CAGACACGGA CCCCTTCACG CCCAGCGGCT CCATGCCTCT GTCGTCCACA 
GGGGATGGGA TTTCTGATTC AGTATGGACC CCTTCCAATA AGCCCATTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006716618.1
CDS	195..2105
Translation	MLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWRFYESVVSFPFFRKEQLEAASSQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTGDPMAEDRGYGNDFPIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTFPSQQSPRNEPYVARPSTSEIEDQSMMGKFVKVERQVQDMGKKLDFLVDMHMQHMERLQVQVTEYYPTKGTSSPAEAEKKEDNRYSDLKTIICNYSETGPPEPPYSFHQVTIDKVSPYGFFAHDPVNLPRGGPSSGKVQATPPSSATTYVERPTVLPILTLLDSRVSCHSQADLQGPYSDRISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPNGGSSWMREKRYLAEGETDTDTDPFTPSGSMPLSSTGDGISDSVWTPSNKPI

Target ORF information:

RefSeq Version	XM_006716555.3
Organism	Homo sapiens(human)
Definition	Homo sapiens potassium voltage-gated channel subfamily Q member 3 (KCNQ3), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006716555.3

ORF Insert Sequence:

ATGCTGCGGA TGGACCGGAG AGGTGGCACC TGGAAGCTTC TGGGCTCAGC CATCTGTGCC 
CACAGCAAAG AACTCATCAC GGCCTGGTAC ATCGGTTTCC TGACACTCAT CCTTTCTTCA 
TTTCTTGTCT ACCTGGTTGA GAAAGACGTC CCAGAGGTGG ATGCACAAGG AGAGGAGATG 
AAAGAGGAGT TTGAGACCTA TGCAGATGCC CTGTGGTGGG GCCTGATCAC ACTGGCCACC 
ATTGGCTATG GAGACAAGAC ACCCAAAACG TGGGAAGGCC GTCTGATTGC CGCCACCTTT 
TCCTTAATTG GCGTCTCCTT TTTTGCCCTT CCAGCGGGCA TCCTGGGGTC CGGGCTGGCC 
CTCAAGGTGC AGGAGCAACA CCGTCAGAAG CACTTTGAGA AAAGGAGGAA GCCAGCTGCT 
GAGCTCATTC AGGCTGCCTG GAGGTATTAT GCTACCAACC CCAACAGGAT TGACCTGGTG 
GCGACATGGA GATTTTATGA ATCAGTCGTC TCTTTTCCTT TCTTCAGGAA AGAACAGCTG 
GAGGCAGCAT CCAGCCAAAA GCTGGGTCTC TTGGATCGGG TTCGCCTTTC TAATCCTCGT 
GGTAGCAATA CTAAAGGAAA GCTATTTACC CCTCTGAATG TAGATGCCAT AGAAGAAAGT 
CCTTCTAAAG AACCAAAGCC TGTTGGCTTA AACAATAAAG AGCGTTTCCG CACGGCCTTC 
CGCATGAAAG CCTACGCTTT CTGGCAGAGT TCTGAAGATG CCGGGACAGG TGACCCCATG 
GCGGAAGACA GGGGCTATGG GAATGACTTC CCCATCGAAG ACATGATCCC CACCCTGAAG 
GCCGCCATCC GAGCCGTCAG AATTCTACAA TTCCGTCTCT ATAAAAAAAA ATTCAAGGAG 
ACTTTGAGGC CTTACGATGT GAAGGATGTG ATTGAGCAGT ATTCTGCCGG GCATCTCGAC 
ATGCTTTCCA GGATAAAGTA CCTTCAGACG AGAATAGATA TGATTTTCAC CCCTGGACCT 
CCCTCCACGC CAAAACACAA GAAGTCTCAG AAAGGGTCAG CATTCACCTT CCCATCCCAG 
CAATCTCCCA GGAATGAACC ATATGTAGCC AGACCATCCA CATCAGAAAT CGAAGACCAA 
AGCATGATGG GGAAGTTTGT AAAAGTTGAA AGACAGGTTC AGGACATGGG GAAGAAGCTG 
GACTTCCTCG TGGATATGCA CATGCAACAC ATGGAACGGT TGCAGGTGCA GGTCACGGAG 
TATTACCCAA CCAAGGGCAC CTCCTCGCCA GCTGAAGCAG AGAAGAAGGA GGACAACAGG 
TATTCCGATT TGAAAACCAT CATCTGCAAC TATTCTGAGA CAGGCCCCCC GGAACCACCC 
TACAGCTTCC ACCAGGTGAC CATTGACAAA GTCAGCCCCT ATGGGTTTTT TGCACATGAC 
CCTGTGAACC TGCCCCGAGG GGGACCCAGT TCTGGAAAGG TTCAGGCAAC TCCTCCTTCC 
TCAGCAACAA CGTATGTGGA GAGGCCCACG GTCCTGCCTA TCTTGACTCT TCTCGACTCC 
CGAGTGAGCT GCCACTCCCA GGCTGACCTG CAGGGCCCCT ACTCGGACCG AATCTCCCCC 
CGGCAGAGAC GTAGCATCAC GCGAGACAGT GACACACCTC TGTCCCTGAT GTCGGTCAAC 
CACGAGGAGC TGGAGAGGTC TCCAAGTGGC TTCAGCATCT CCCAGGACAG AGATGATTAT 
GTGTTCGGCC CCAATGGGGG GTCGAGCTGG ATGAGGGAGA AGCGGTACCT CGCCGAGGGT 
GAGACGGACA CAGACACGGA CCCCTTCACG CCCAGCGGCT CCATGCCTCT GTCGTCCACA 
GGGGATGGGA TTTCTGATTC AGTATGGACC CCTTCCAATA AGCCCATTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KCNQ3 ( XM_005250914.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005250971.1 Homo sapiens potassium voltage-gated channel subfamily Q member 3 (KCNQ3), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu42446
Clone ID Related Accession (Same CDS sequence)	XM_005250914.3
Accession Version	XM_005250914.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1374bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	potassium voltage-gated channel subfamily KQT member 3 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005250914.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTACCAA CCCCAACAGG ATTGACCTGG TGGCGACATG GAGATTTTAT GAATCAGTCG 
TCTCTTTTCC TTTCTTCAGG AAAGAACAGC TGGAGGCAGC ATCCAGATGC CATAGAAGAA 
AGTCCTTCTA AAGAACCAAA GCCTGTTGGC TTAAACAATA AAGAGCGTTT CCGCACGGCC 
TTCCGCATGA AAGCCTACGC TTTCTGGCAG AGTTCTGAAG ATGCCGGGAC AGGTGACCCC 
ATGGCGGAAG ACAGGGGCTA TGGGAATGAC TTCCCCATCG AAGACATGAT CCCCACCCTG 
AAGGCCGCCA TCCGAGCCGT CAGAATTCTA CAATTCCGTC TCTATAAAAA AAAATTCAAG 
GAGACTTTGA GGCCTTACGA TGTGAAGGAT GTGATTGAGC AGTATTCTGC CGGGCATCTC 
GACATGCTTT CCAGGATAAA GTACCTTCAG ACGAGAATAG ATATGATTTT CACCCCTGGA 
CCTCCCTCCA CGCCAAAACA CAAGAAGTCT CAGAAAGGGT CAGCATTCAC CTTCCCATCC 
CAGCAATCTC CCAGGAATGA ACCATATGTA GCCAGACCAT CCACATCAGA AATCGAAGAC 
CAAAGCATGA TGGGGAAGTT TGTAAAAGTT GAAAGACAGG TTCAGGACAT GGGGAAGAAG 
CTGGACTTCC TCGTGGATAT GCACATGCAA CACATGGAAC GGTTGCAGGT GCAGGTCACG 
GAGTATTACC CAACCAAGGG CACCTCCTCG CCAGCTGAAG CAGAGAAGAA GGAGGACAAC 
AGGTATTCCG ATTTGAAAAC CATCATCTGC AACTATTCTG AGACAGGCCC CCCGGAACCA 
CCCTACAGCT TCCACCAGGT GACCATTGAC AAAGTCAGCC CCTATGGGTT TTTTGCACAT 
GACCCTGTGA ACCTGCCCCG AGGGGGACCC AGTTCTGGAA AGGTTCAGGC AACTCCTCCT 
TCCTCAGCAA CAACGTATGT GGAGAGGCCC ACGGTCCTGC CTATCTTGAC TCTTCTCGAC 
TCCCGAGTGA GCTGCCACTC CCAGGCTGAC CTGCAGGGCC CCTACTCGGA CCGAATCTCC 
CCCCGGCAGA GACGTAGCAT CACGCGAGAC AGTGACACAC CTCTGTCCCT GATGTCGGTC 
AACCACGAGG AGCTGGAGAG GTCTCCAAGT GGCTTCAGCA TCTCCCAGGA CAGAGATGAT 
TATGTGTTCG GCCCCAATGG GGGGTCGAGC TGGATGAGGG AGAAGCGGTA CCTCGCCGAG 
GGTGAGACGG ACACAGACAC GGACCCCTTC ACGCCCAGCG GCTCCATGCC TCTGTCGTCC 
ACAGGGGATG GGATTTCTGA TTCAGTATGG ACCCCTTCCA ATAAGCCCAT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005250971.1
CDS	546..1919
Translation	MLPTPTGLTWWRHGDFMNQSSLFLSSGKNSWRQHPDAIEESPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTGDPMAEDRGYGNDFPIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTFPSQQSPRNEPYVARPSTSEIEDQSMMGKFVKVERQVQDMGKKLDFLVDMHMQHMERLQVQVTEYYPTKGTSSPAEAEKKEDNRYSDLKTIICNYSETGPPEPPYSFHQVTIDKVSPYGFFAHDPVNLPRGGPSSGKVQATPPSSATTYVERPTVLPILTLLDSRVSCHSQADLQGPYSDRISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPNGGSSWMREKRYLAEGETDTDTDPFTPSGSMPLSSTGDGISDSVWTPSNKPI

Target ORF information:

RefSeq Version	XM_005250914.3
Organism	Homo sapiens(human)
Definition	Homo sapiens potassium voltage-gated channel subfamily Q member 3 (KCNQ3), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005250914.3

ORF Insert Sequence:

ATGCTACCAA CCCCAACAGG ATTGACCTGG TGGCGACATG GAGATTTTAT GAATCAGTCG 
TCTCTTTTCC TTTCTTCAGG AAAGAACAGC TGGAGGCAGC ATCCAGATGC CATAGAAGAA 
AGTCCTTCTA AAGAACCAAA GCCTGTTGGC TTAAACAATA AAGAGCGTTT CCGCACGGCC 
TTCCGCATGA AAGCCTACGC TTTCTGGCAG AGTTCTGAAG ATGCCGGGAC AGGTGACCCC 
ATGGCGGAAG ACAGGGGCTA TGGGAATGAC TTCCCCATCG AAGACATGAT CCCCACCCTG 
AAGGCCGCCA TCCGAGCCGT CAGAATTCTA CAATTCCGTC TCTATAAAAA AAAATTCAAG 
GAGACTTTGA GGCCTTACGA TGTGAAGGAT GTGATTGAGC AGTATTCTGC CGGGCATCTC 
GACATGCTTT CCAGGATAAA GTACCTTCAG ACGAGAATAG ATATGATTTT CACCCCTGGA 
CCTCCCTCCA CGCCAAAACA CAAGAAGTCT CAGAAAGGGT CAGCATTCAC CTTCCCATCC 
CAGCAATCTC CCAGGAATGA ACCATATGTA GCCAGACCAT CCACATCAGA AATCGAAGAC 
CAAAGCATGA TGGGGAAGTT TGTAAAAGTT GAAAGACAGG TTCAGGACAT GGGGAAGAAG 
CTGGACTTCC TCGTGGATAT GCACATGCAA CACATGGAAC GGTTGCAGGT GCAGGTCACG 
GAGTATTACC CAACCAAGGG CACCTCCTCG CCAGCTGAAG CAGAGAAGAA GGAGGACAAC 
AGGTATTCCG ATTTGAAAAC CATCATCTGC AACTATTCTG AGACAGGCCC CCCGGAACCA 
CCCTACAGCT TCCACCAGGT GACCATTGAC AAAGTCAGCC CCTATGGGTT TTTTGCACAT 
GACCCTGTGA ACCTGCCCCG AGGGGGACCC AGTTCTGGAA AGGTTCAGGC AACTCCTCCT 
TCCTCAGCAA CAACGTATGT GGAGAGGCCC ACGGTCCTGC CTATCTTGAC TCTTCTCGAC 
TCCCGAGTGA GCTGCCACTC CCAGGCTGAC CTGCAGGGCC CCTACTCGGA CCGAATCTCC 
CCCCGGCAGA GACGTAGCAT CACGCGAGAC AGTGACACAC CTCTGTCCCT GATGTCGGTC 
AACCACGAGG AGCTGGAGAG GTCTCCAAGT GGCTTCAGCA TCTCCCAGGA CAGAGATGAT 
TATGTGTTCG GCCCCAATGG GGGGTCGAGC TGGATGAGGG AGAAGCGGTA CCTCGCCGAG 
GGTGAGACGG ACACAGACAC GGACCCCTTC ACGCCCAGCG GCTCCATGCC TCTGTCGTCC 
ACAGGGGATG GGATTTCTGA TTCAGTATGG ACCCCTTCCA ATAAGCCCAT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KCNQ3 ( NM_001204824.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001191753.1 Homo sapiens potassium voltage-gated channel subfamily Q member 3 (KCNQ3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu24538
Clone ID Related Accession (Same CDS sequence)	NM_001204824.1
Accession Version	NM_001204824.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2259bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Homo sapiens(human)
Product	potassium voltage-gated channel subfamily KQT member 3 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK296293.1, AF033347.1, AC131042.6 and BX538233.1. Transcript Variant: This variant (2) contains an alternate 5' terminal exon and it thus differs in the 5' UTR and 5' coding region, compared to variant 1. The resulting isoform (2) has a distinct N-terminus and is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1966682, SAMEA1968189 [ECO:0000350] ##Evidence-Data-END##

ATGAAGCCTG CAGAACACGC CACGATGTTC CTGATTGTCC TGGGGTGCTT GATTCTGGCT 
GTCCTGACCA CATTCAAGGA GTATGAGACT GTCTCGGGAG ACTGGCTTCT GTTACTGGAG 
ACATTTGCTA TTTTCATCTT TGGAGCCGAG TTTGCTTTGA GGATCTGGGC TGCTGGATGT 
TGCTGCCGAT ACAAAGGCTG GCGGGGCCGA CTGAAGTTTG CCAGGAAGCC CCTGTGCATG 
TTGGACATCT TTGTGCTGAT TGCCTCTGTG CCAGTGGTTG CTGTGGGAAA CCAAGGCAAT 
GTTCTGGCCA CCTCCCTGCG AAGCCTGCGC TTCCTGCAGA TCCTGCGCAT GCTGCGGATG 
GACCGGAGAG GTGGCACCTG GAAGCTTCTG GGCTCAGCCA TCTGTGCCCA CAGCAAAGAA 
CTCATCACGG CCTGGTACAT CGGTTTCCTG ACACTCATCC TTTCTTCATT TCTTGTCTAC 
CTGGTTGAGA AAGACGTCCC AGAGGTGGAT GCACAAGGAG AGGAGATGAA AGAGGAGTTT 
GAGACCTATG CAGATGCCCT GTGGTGGGGC CTGATCACAC TGGCCACCAT TGGCTATGGA 
GACAAGACAC CCAAAACGTG GGAAGGCCGT CTGATTGCCG CCACCTTTTC CTTAATTGGC 
GTCTCCTTTT TTGCCCTTCC AGCGGGCATC CTGGGGTCCG GGCTGGCCCT CAAGGTGCAG 
GAGCAACACC GTCAGAAGCA CTTTGAGAAA AGGAGGAAGC CAGCTGCTGA GCTCATTCAG 
GCTGCCTGGA GGTATTATGC TACCAACCCC AACAGGATTG ACCTGGTGGC GACATGGAGA 
TTTTATGAAT CAGTCGTCTC TTTTCCTTTC TTCAGGAAAG AACAGCTGGA GGCAGCATCC 
AGCCAAAAGC TGGGTCTCTT GGATCGGGTT CGCCTTTCTA ATCCTCGTGG TAGCAATACT 
AAAGGAAAGC TATTTACCCC TCTGAATGTA GATGCCATAG AAGAAAGTCC TTCTAAAGAA 
CCAAAGCCTG TTGGCTTAAA CAATAAAGAG CGTTTCCGCA CGGCCTTCCG CATGAAAGCC 
TACGCTTTCT GGCAGAGTTC TGAAGATGCC GGGACAGGTG ACCCCATGGC GGAAGACAGG 
GGCTATGGGA ATGACTTCCC CATCGAAGAC ATGATCCCCA CCCTGAAGGC CGCCATCCGA 
GCCGTCAGAA TTCTACAATT CCGTCTCTAT AAAAAAAAAT TCAAGGAGAC TTTGAGGCCT 
TACGATGTGA AGGATGTGAT TGAGCAGTAT TCTGCCGGGC ATCTCGACAT GCTTTCCAGG 
ATAAAGTACC TTCAGACGAG AATAGATATG ATTTTCACCC CTGGACCTCC CTCCACGCCA 
AAACACAAGA AGTCTCAGAA AGGGTCAGCA TTCACCTTCC CATCCCAGCA ATCTCCCAGG 
AATGAACCAT ATGTAGCCAG ACCATCCACA TCAGAAATCG AAGACCAAAG CATGATGGGG 
AAGTTTGTAA AAGTTGAAAG ACAGGTTCAG GACATGGGGA AGAAGCTGGA CTTCCTCGTG 
GATATGCACA TGCAACACAT GGAACGGTTG CAGGTGCAGG TCACGGAGTA TTACCCAACC 
AAGGGCACCT CCTCGCCAGC TGAAGCAGAG AAGAAGGAGG ACAACAGGTA TTCCGATTTG 
AAAACCATCA TCTGCAACTA TTCTGAGACA GGCCCCCCGG AACCACCCTA CAGCTTCCAC 
CAGGTGACCA TTGACAAAGT CAGCCCCTAT GGGTTTTTTG CACATGACCC TGTGAACCTG 
CCCCGAGGGG GACCCAGTTC TGGAAAGGTT CAGGCAACTC CTCCTTCCTC AGCAACAACG 
TATGTGGAGA GGCCCACGGT CCTGCCTATC TTGACTCTTC TCGACTCCCG AGTGAGCTGC 
CACTCCCAGG CTGACCTGCA GGGCCCCTAC TCGGACCGAA TCTCCCCCCG GCAGAGACGT 
AGCATCACGC GAGACAGTGA CACACCTCTG TCCCTGATGT CGGTCAACCA CGAGGAGCTG 
GAGAGGTCTC CAAGTGGCTT CAGCATCTCC CAGGACAGAG ATGATTATGT GTTCGGCCCC 
AATGGGGGGT CGAGCTGGAT GAGGGAGAAG CGGTACCTCG CCGAGGGTGA GACGGACACA 
GACACGGACC CCTTCACGCC CAGCGGCTCC ATGCCTCTGT CGTCCACAGG GGATGGGATT 
TCTGATTCAG TATGGACCCC TTCCAATAAG CCCATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001191753.1
CDS	37..2295
Translation	MKPAEHATMFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWRFYESVVSFPFFRKEQLEAASSQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTGDPMAEDRGYGNDFPIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTFPSQQSPRNEPYVARPSTSEIEDQSMMGKFVKVERQVQDMGKKLDFLVDMHMQHMERLQVQVTEYYPTKGTSSPAEAEKKEDNRYSDLKTIICNYSETGPPEPPYSFHQVTIDKVSPYGFFAHDPVNLPRGGPSSGKVQATPPSSATTYVERPTVLPILTLLDSRVSCHSQADLQGPYSDRISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPNGGSSWMREKRYLAEGETDTDTDPFTPSGSMPLSSTGDGISDSVWTPSNKPI

Target ORF information:

RefSeq Version	NM_001204824.1
Organism	Homo sapiens(human)
Definition	Homo sapiens potassium voltage-gated channel subfamily Q member 3 (KCNQ3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001204824.1

ORF Insert Sequence:

ATGAAGCCTG CAGAACACGC CACGATGTTC CTGATTGTCC TGGGGTGCTT GATTCTGGCT 
GTCCTGACCA CATTCAAGGA GTATGAGACT GTCTCGGGAG ACTGGCTTCT GTTACTGGAG 
ACATTTGCTA TTTTCATCTT TGGAGCCGAG TTTGCTTTGA GGATCTGGGC TGCTGGATGT 
TGCTGCCGAT ACAAAGGCTG GCGGGGCCGA CTGAAGTTTG CCAGGAAGCC CCTGTGCATG 
TTGGACATCT TTGTGCTGAT TGCCTCTGTG CCAGTGGTTG CTGTGGGAAA CCAAGGCAAT 
GTTCTGGCCA CCTCCCTGCG AAGCCTGCGC TTCCTGCAGA TCCTGCGCAT GCTGCGGATG 
GACCGGAGAG GTGGCACCTG GAAGCTTCTG GGCTCAGCCA TCTGTGCCCA CAGCAAAGAA 
CTCATCACGG CCTGGTACAT CGGTTTCCTG ACACTCATCC TTTCTTCATT TCTTGTCTAC 
CTGGTTGAGA AAGACGTCCC AGAGGTGGAT GCACAAGGAG AGGAGATGAA AGAGGAGTTT 
GAGACCTATG CAGATGCCCT GTGGTGGGGC CTGATCACAC TGGCCACCAT TGGCTATGGA 
GACAAGACAC CCAAAACGTG GGAAGGCCGT CTGATTGCCG CCACCTTTTC CTTAATTGGC 
GTCTCCTTTT TTGCCCTTCC AGCGGGCATC CTGGGGTCCG GGCTGGCCCT CAAGGTGCAG 
GAGCAACACC GTCAGAAGCA CTTTGAGAAA AGGAGGAAGC CAGCTGCTGA GCTCATTCAG 
GCTGCCTGGA GGTATTATGC TACCAACCCC AACAGGATTG ACCTGGTGGC GACATGGAGA 
TTTTATGAAT CAGTCGTCTC TTTTCCTTTC TTCAGGAAAG AACAGCTGGA GGCAGCATCC 
AGCCAAAAGC TGGGTCTCTT GGATCGGGTT CGCCTTTCTA ATCCTCGTGG TAGCAATACT 
AAAGGAAAGC TATTTACCCC TCTGAATGTA GATGCCATAG AAGAAAGTCC TTCTAAAGAA 
CCAAAGCCTG TTGGCTTAAA CAATAAAGAG CGTTTCCGCA CGGCCTTCCG CATGAAAGCC 
TACGCTTTCT GGCAGAGTTC TGAAGATGCC GGGACAGGTG ACCCCATGGC GGAAGACAGG 
GGCTATGGGA ATGACTTCCC CATCGAAGAC ATGATCCCCA CCCTGAAGGC CGCCATCCGA 
GCCGTCAGAA TTCTACAATT CCGTCTCTAT AAAAAAAAAT TCAAGGAGAC TTTGAGGCCT 
TACGATGTGA AGGATGTGAT TGAGCAGTAT TCTGCCGGGC ATCTCGACAT GCTTTCCAGG 
ATAAAGTACC TTCAGACGAG AATAGATATG ATTTTCACCC CTGGACCTCC CTCCACGCCA 
AAACACAAGA AGTCTCAGAA AGGGTCAGCA TTCACCTTCC CATCCCAGCA ATCTCCCAGG 
AATGAACCAT ATGTAGCCAG ACCATCCACA TCAGAAATCG AAGACCAAAG CATGATGGGG 
AAGTTTGTAA AAGTTGAAAG ACAGGTTCAG GACATGGGGA AGAAGCTGGA CTTCCTCGTG 
GATATGCACA TGCAACACAT GGAACGGTTG CAGGTGCAGG TCACGGAGTA TTACCCAACC 
AAGGGCACCT CCTCGCCAGC TGAAGCAGAG AAGAAGGAGG ACAACAGGTA TTCCGATTTG 
AAAACCATCA TCTGCAACTA TTCTGAGACA GGCCCCCCGG AACCACCCTA CAGCTTCCAC 
CAGGTGACCA TTGACAAAGT CAGCCCCTAT GGGTTTTTTG CACATGACCC TGTGAACCTG 
CCCCGAGGGG GACCCAGTTC TGGAAAGGTT CAGGCAACTC CTCCTTCCTC AGCAACAACG 
TATGTGGAGA GGCCCACGGT CCTGCCTATC TTGACTCTTC TCGACTCCCG AGTGAGCTGC 
CACTCCCAGG CTGACCTGCA GGGCCCCTAC TCGGACCGAA TCTCCCCCCG GCAGAGACGT 
AGCATCACGC GAGACAGTGA CACACCTCTG TCCCTGATGT CGGTCAACCA CGAGGAGCTG 
GAGAGGTCTC CAAGTGGCTT CAGCATCTCC CAGGACAGAG ATGATTATGT GTTCGGCCCC 
AATGGGGGGT CGAGCTGGAT GAGGGAGAAG CGGTACCTCG CCGAGGGTGA GACGGACACA 
GACACGGACC CCTTCACGCC CAGCGGCTCC ATGCCTCTGT CGTCCACAGG GGATGGGATT 
TCTGATTCAG TATGGACCCC TTCCAATAAG CCCATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KCNQ3 ( XM_011517026.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011515328.1 Homo sapiens potassium voltage-gated channel subfamily Q member 3 (KCNQ3), transcript variant X2, mRNA.

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CloneID	OHu58600
Clone ID Related Accession (Same CDS sequence)	XM_011517026.2
Accession Version	XM_011517026.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2259bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	potassium voltage-gated channel subfamily KQT member 3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011517026.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCTGCT CAACATCATG TAGCAGGTTC CTGATTGTCC TGGGGTGCTT GATTCTGGCT 
GTCCTGACCA CATTCAAGGA GTATGAGACT GTCTCGGGAG ACTGGCTTCT GTTACTGGAG 
ACATTTGCTA TTTTCATCTT TGGAGCCGAG TTTGCTTTGA GGATCTGGGC TGCTGGATGT 
TGCTGCCGAT ACAAAGGCTG GCGGGGCCGA CTGAAGTTTG CCAGGAAGCC CCTGTGCATG 
TTGGACATCT TTGTGCTGAT TGCCTCTGTG CCAGTGGTTG CTGTGGGAAA CCAAGGCAAT 
GTTCTGGCCA CCTCCCTGCG AAGCCTGCGC TTCCTGCAGA TCCTGCGCAT GCTGCGGATG 
GACCGGAGAG GTGGCACCTG GAAGCTTCTG GGCTCAGCCA TCTGTGCCCA CAGCAAAGAA 
CTCATCACGG CCTGGTACAT CGGTTTCCTG ACACTCATCC TTTCTTCATT TCTTGTCTAC 
CTGGTTGAGA AAGACGTCCC AGAGGTGGAT GCACAAGGAG AGGAGATGAA AGAGGAGTTT 
GAGACCTATG CAGATGCCCT GTGGTGGGGC CTGATCACAC TGGCCACCAT TGGCTATGGA 
GACAAGACAC CCAAAACGTG GGAAGGCCGT CTGATTGCCG CCACCTTTTC CTTAATTGGC 
GTCTCCTTTT TTGCCCTTCC AGCGGGCATC CTGGGGTCCG GGCTGGCCCT CAAGGTGCAG 
GAGCAACACC GTCAGAAGCA CTTTGAGAAA AGGAGGAAGC CAGCTGCTGA GCTCATTCAG 
GCTGCCTGGA GGTATTATGC TACCAACCCC AACAGGATTG ACCTGGTGGC GACATGGAGA 
TTTTATGAAT CAGTCGTCTC TTTTCCTTTC TTCAGGAAAG AACAGCTGGA GGCAGCATCC 
AGCCAAAAGC TGGGTCTCTT GGATCGGGTT CGCCTTTCTA ATCCTCGTGG TAGCAATACT 
AAAGGAAAGC TATTTACCCC TCTGAATGTA GATGCCATAG AAGAAAGTCC TTCTAAAGAA 
CCAAAGCCTG TTGGCTTAAA CAATAAAGAG CGTTTCCGCA CGGCCTTCCG CATGAAAGCC 
TACGCTTTCT GGCAGAGTTC TGAAGATGCC GGGACAGGTG ACCCCATGGC GGAAGACAGG 
GGCTATGGGA ATGACTTCCC CATCGAAGAC ATGATCCCCA CCCTGAAGGC CGCCATCCGA 
GCCGTCAGAA TTCTACAATT CCGTCTCTAT AAAAAAAAAT TCAAGGAGAC TTTGAGGCCT 
TACGATGTGA AGGATGTGAT TGAGCAGTAT TCTGCCGGGC ATCTCGACAT GCTTTCCAGG 
ATAAAGTACC TTCAGACGAG AATAGATATG ATTTTCACCC CTGGACCTCC CTCCACGCCA 
AAACACAAGA AGTCTCAGAA AGGGTCAGCA TTCACCTTCC CATCCCAGCA ATCTCCCAGG 
AATGAACCAT ATGTAGCCAG ACCATCCACA TCAGAAATCG AAGACCAAAG CATGATGGGG 
AAGTTTGTAA AAGTTGAAAG ACAGGTTCAG GACATGGGGA AGAAGCTGGA CTTCCTCGTG 
GATATGCACA TGCAACACAT GGAACGGTTG CAGGTGCAGG TCACGGAGTA TTACCCAACC 
AAGGGCACCT CCTCGCCAGC TGAAGCAGAG AAGAAGGAGG ACAACAGGTA TTCCGATTTG 
AAAACCATCA TCTGCAACTA TTCTGAGACA GGCCCCCCGG AACCACCCTA CAGCTTCCAC 
CAGGTGACCA TTGACAAAGT CAGCCCCTAT GGGTTTTTTG CACATGACCC TGTGAACCTG 
CCCCGAGGGG GACCCAGTTC TGGAAAGGTT CAGGCAACTC CTCCTTCCTC AGCAACAACG 
TATGTGGAGA GGCCCACGGT CCTGCCTATC TTGACTCTTC TCGACTCCCG AGTGAGCTGC 
CACTCCCAGG CTGACCTGCA GGGCCCCTAC TCGGACCGAA TCTCCCCCCG GCAGAGACGT 
AGCATCACGC GAGACAGTGA CACACCTCTG TCCCTGATGT CGGTCAACCA CGAGGAGCTG 
GAGAGGTCTC CAAGTGGCTT CAGCATCTCC CAGGACAGAG ATGATTATGT GTTCGGCCCC 
AATGGGGGGT CGAGCTGGAT GAGGGAGAAG CGGTACCTCG CCGAGGGTGA GACGGACACA 
GACACGGACC CCTTCACGCC CAGCGGCTCC ATGCCTCTGT CGTCCACAGG GGATGGGATT 
TCTGATTCAG TATGGACCCC TTCCAATAAG CCCATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011515328.1
CDS	3120..5378
Translation	MTCSTSCSRFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWRFYESVVSFPFFRKEQLEAASSQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTGDPMAEDRGYGNDFPIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTFPSQQSPRNEPYVARPSTSEIEDQSMMGKFVKVERQVQDMGKKLDFLVDMHMQHMERLQVQVTEYYPTKGTSSPAEAEKKEDNRYSDLKTIICNYSETGPPEPPYSFHQVTIDKVSPYGFFAHDPVNLPRGGPSSGKVQATPPSSATTYVERPTVLPILTLLDSRVSCHSQADLQGPYSDRISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPNGGSSWMREKRYLAEGETDTDTDPFTPSGSMPLSSTGDGISDSVWTPSNKPI

Target ORF information:

RefSeq Version	XM_011517026.2
Organism	Homo sapiens(human)
Definition	Homo sapiens potassium voltage-gated channel subfamily Q member 3 (KCNQ3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011517026.2

ORF Insert Sequence:

ATGACCTGCT CAACATCATG TAGCAGGTTC CTGATTGTCC TGGGGTGCTT GATTCTGGCT 
GTCCTGACCA CATTCAAGGA GTATGAGACT GTCTCGGGAG ACTGGCTTCT GTTACTGGAG 
ACATTTGCTA TTTTCATCTT TGGAGCCGAG TTTGCTTTGA GGATCTGGGC TGCTGGATGT 
TGCTGCCGAT ACAAAGGCTG GCGGGGCCGA CTGAAGTTTG CCAGGAAGCC CCTGTGCATG 
TTGGACATCT TTGTGCTGAT TGCCTCTGTG CCAGTGGTTG CTGTGGGAAA CCAAGGCAAT 
GTTCTGGCCA CCTCCCTGCG AAGCCTGCGC TTCCTGCAGA TCCTGCGCAT GCTGCGGATG 
GACCGGAGAG GTGGCACCTG GAAGCTTCTG GGCTCAGCCA TCTGTGCCCA CAGCAAAGAA 
CTCATCACGG CCTGGTACAT CGGTTTCCTG ACACTCATCC TTTCTTCATT TCTTGTCTAC 
CTGGTTGAGA AAGACGTCCC AGAGGTGGAT GCACAAGGAG AGGAGATGAA AGAGGAGTTT 
GAGACCTATG CAGATGCCCT GTGGTGGGGC CTGATCACAC TGGCCACCAT TGGCTATGGA 
GACAAGACAC CCAAAACGTG GGAAGGCCGT CTGATTGCCG CCACCTTTTC CTTAATTGGC 
GTCTCCTTTT TTGCCCTTCC AGCGGGCATC CTGGGGTCCG GGCTGGCCCT CAAGGTGCAG 
GAGCAACACC GTCAGAAGCA CTTTGAGAAA AGGAGGAAGC CAGCTGCTGA GCTCATTCAG 
GCTGCCTGGA GGTATTATGC TACCAACCCC AACAGGATTG ACCTGGTGGC GACATGGAGA 
TTTTATGAAT CAGTCGTCTC TTTTCCTTTC TTCAGGAAAG AACAGCTGGA GGCAGCATCC 
AGCCAAAAGC TGGGTCTCTT GGATCGGGTT CGCCTTTCTA ATCCTCGTGG TAGCAATACT 
AAAGGAAAGC TATTTACCCC TCTGAATGTA GATGCCATAG AAGAAAGTCC TTCTAAAGAA 
CCAAAGCCTG TTGGCTTAAA CAATAAAGAG CGTTTCCGCA CGGCCTTCCG CATGAAAGCC 
TACGCTTTCT GGCAGAGTTC TGAAGATGCC GGGACAGGTG ACCCCATGGC GGAAGACAGG 
GGCTATGGGA ATGACTTCCC CATCGAAGAC ATGATCCCCA CCCTGAAGGC CGCCATCCGA 
GCCGTCAGAA TTCTACAATT CCGTCTCTAT AAAAAAAAAT TCAAGGAGAC TTTGAGGCCT 
TACGATGTGA AGGATGTGAT TGAGCAGTAT TCTGCCGGGC ATCTCGACAT GCTTTCCAGG 
ATAAAGTACC TTCAGACGAG AATAGATATG ATTTTCACCC CTGGACCTCC CTCCACGCCA 
AAACACAAGA AGTCTCAGAA AGGGTCAGCA TTCACCTTCC CATCCCAGCA ATCTCCCAGG 
AATGAACCAT ATGTAGCCAG ACCATCCACA TCAGAAATCG AAGACCAAAG CATGATGGGG 
AAGTTTGTAA AAGTTGAAAG ACAGGTTCAG GACATGGGGA AGAAGCTGGA CTTCCTCGTG 
GATATGCACA TGCAACACAT GGAACGGTTG CAGGTGCAGG TCACGGAGTA TTACCCAACC 
AAGGGCACCT CCTCGCCAGC TGAAGCAGAG AAGAAGGAGG ACAACAGGTA TTCCGATTTG 
AAAACCATCA TCTGCAACTA TTCTGAGACA GGCCCCCCGG AACCACCCTA CAGCTTCCAC 
CAGGTGACCA TTGACAAAGT CAGCCCCTAT GGGTTTTTTG CACATGACCC TGTGAACCTG 
CCCCGAGGGG GACCCAGTTC TGGAAAGGTT CAGGCAACTC CTCCTTCCTC AGCAACAACG 
TATGTGGAGA GGCCCACGGT CCTGCCTATC TTGACTCTTC TCGACTCCCG AGTGAGCTGC 
CACTCCCAGG CTGACCTGCA GGGCCCCTAC TCGGACCGAA TCTCCCCCCG GCAGAGACGT 
AGCATCACGC GAGACAGTGA CACACCTCTG TCCCTGATGT CGGTCAACCA CGAGGAGCTG 
GAGAGGTCTC CAAGTGGCTT CAGCATCTCC CAGGACAGAG ATGATTATGT GTTCGGCCCC 
AATGGGGGGT CGAGCTGGAT GAGGGAGAAG CGGTACCTCG CCGAGGGTGA GACGGACACA 
GACACGGACC CCTTCACGCC CAGCGGCTCC ATGCCTCTGT CGTCCACAGG GGATGGGATT 
TCTGATTCAG TATGGACCCC TTCCAATAAG CCCATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KCNQ3 ( XM_017013400.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016868889.1 Homo sapiens potassium voltage-gated channel subfamily Q member 3 (KCNQ3), transcript variant X1, mRNA.

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CloneID	OHu97962
Clone ID Related Accession (Same CDS sequence)	XM_017013400.1
Accession Version	XM_017013400.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2397bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	potassium voltage-gated channel subfamily KQT member 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACTCAGA GCCAACCAGG AAATGACCCA GTATGCTTGG CTACTTCTGA GAAGCATCCT 
TGTGTGTCTG TGTGGGAAGG GAGAGCAAAC AGAAGCAGGA GGGCCATGGT GGCACAGGCA 
TGGAGGACCT CAATGAGGAA GCAGAGGGAG GAAGCGTGTT TCAGGTTCCT GATTGTCCTG 
GGGTGCTTGA TTCTGGCTGT CCTGACCACA TTCAAGGAGT ATGAGACTGT CTCGGGAGAC 
TGGCTTCTGT TACTGGAGAC ATTTGCTATT TTCATCTTTG GAGCCGAGTT TGCTTTGAGG 
ATCTGGGCTG CTGGATGTTG CTGCCGATAC AAAGGCTGGC GGGGCCGACT GAAGTTTGCC 
AGGAAGCCCC TGTGCATGTT GGACATCTTT GTGCTGATTG CCTCTGTGCC AGTGGTTGCT 
GTGGGAAACC AAGGCAATGT TCTGGCCACC TCCCTGCGAA GCCTGCGCTT CCTGCAGATC 
CTGCGCATGC TGCGGATGGA CCGGAGAGGT GGCACCTGGA AGCTTCTGGG CTCAGCCATC 
TGTGCCCACA GCAAAGAACT CATCACGGCC TGGTACATCG GTTTCCTGAC ACTCATCCTT 
TCTTCATTTC TTGTCTACCT GGTTGAGAAA GACGTCCCAG AGGTGGATGC ACAAGGAGAG 
GAGATGAAAG AGGAGTTTGA GACCTATGCA GATGCCCTGT GGTGGGGCCT GATCACACTG 
GCCACCATTG GCTATGGAGA CAAGACACCC AAAACGTGGG AAGGCCGTCT GATTGCCGCC 
ACCTTTTCCT TAATTGGCGT CTCCTTTTTT GCCCTTCCAG CGGGCATCCT GGGGTCCGGG 
CTGGCCCTCA AGGTGCAGGA GCAACACCGT CAGAAGCACT TTGAGAAAAG GAGGAAGCCA 
GCTGCTGAGC TCATTCAGGC TGCCTGGAGG TATTATGCTA CCAACCCCAA CAGGATTGAC 
CTGGTGGCGA CATGGAGATT TTATGAATCA GTCGTCTCTT TTCCTTTCTT CAGGAAAGAA 
CAGCTGGAGG CAGCATCCAG CCAAAAGCTG GGTCTCTTGG ATCGGGTTCG CCTTTCTAAT 
CCTCGTGGTA GCAATACTAA AGGAAAGCTA TTTACCCCTC TGAATGTAGA TGCCATAGAA 
GAAAGTCCTT CTAAAGAACC AAAGCCTGTT GGCTTAAACA ATAAAGAGCG TTTCCGCACG 
GCCTTCCGCA TGAAAGCCTA CGCTTTCTGG CAGAGTTCTG AAGATGCCGG GACAGGTGAC 
CCCATGGCGG AAGACAGGGG CTATGGGAAT GACTTCCCCA TCGAAGACAT GATCCCCACC 
CTGAAGGCCG CCATCCGAGC CGTCAGAATT CTACAATTCC GTCTCTATAA AAAAAAATTC 
AAGGAGACTT TGAGGCCTTA CGATGTGAAG GATGTGATTG AGCAGTATTC TGCCGGGCAT 
CTCGACATGC TTTCCAGGAT AAAGTACCTT CAGACGAGAA TAGATATGAT TTTCACCCCT 
GGACCTCCCT CCACGCCAAA ACACAAGAAG TCTCAGAAAG GGTCAGCATT CACCTTCCCA 
TCCCAGCAAT CTCCCAGGAA TGAACCATAT GTAGCCAGAC CATCCACATC AGAAATCGAA 
GACCAAAGCA TGATGGGGAA GTTTGTAAAA GTTGAAAGAC AGGTTCAGGA CATGGGGAAG 
AAGCTGGACT TCCTCGTGGA TATGCACATG CAACACATGG AACGGTTGCA GGTGCAGGTC 
ACGGAGTATT ACCCAACCAA GGGCACCTCC TCGCCAGCTG AAGCAGAGAA GAAGGAGGAC 
AACAGGTATT CCGATTTGAA AACCATCATC TGCAACTATT CTGAGACAGG CCCCCCGGAA 
CCACCCTACA GCTTCCACCA GGTGACCATT GACAAAGTCA GCCCCTATGG GTTTTTTGCA 
CATGACCCTG TGAACCTGCC CCGAGGGGGA CCCAGTTCTG GAAAGGTTCA GGCAACTCCT 
CCTTCCTCAG CAACAACGTA TGTGGAGAGG CCCACGGTCC TGCCTATCTT GACTCTTCTC 
GACTCCCGAG TGAGCTGCCA CTCCCAGGCT GACCTGCAGG GCCCCTACTC GGACCGAATC 
TCCCCCCGGC AGAGACGTAG CATCACGCGA GACAGTGACA CACCTCTGTC CCTGATGTCG 
GTCAACCACG AGGAGCTGGA GAGGTCTCCA AGTGGCTTCA GCATCTCCCA GGACAGAGAT 
GATTATGTGT TCGGCCCCAA TGGGGGGTCG AGCTGGATGA GGGAGAAGCG GTACCTCGCC 
GAGGGTGAGA CGGACACAGA CACGGACCCC TTCACGCCCA GCGGCTCCAT GCCTCTGTCG 
TCCACAGGGG ATGGGATTTC TGATTCAGTA TGGACCCCTT CCAATAAGCC CATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016868889.1
CDS	9954..12350
Translation	MTQSQPGNDPVCLATSEKHPCVSVWEGRANRSRRAMVAQAWRTSMRKQREEACFRFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWRFYESVVSFPFFRKEQLEAASSQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTGDPMAEDRGYGNDFPIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTFPSQQSPRNEPYVARPSTSEIEDQSMMGKFVKVERQVQDMGKKLDFLVDMHMQHMERLQVQVTEYYPTKGTSSPAEAEKKEDNRYSDLKTIICNYSETGPPEPPYSFHQVTIDKVSPYGFFAHDPVNLPRGGPSSGKVQATPPSSATTYVERPTVLPILTLLDSRVSCHSQADLQGPYSDRISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPNGGSSWMREKRYLAEGETDTDTDPFTPSGSMPLSSTGDGISDSVWTPSNKPI

Target ORF information:

RefSeq Version	XM_017013400.1
Organism	Homo sapiens(human)
Definition	Homo sapiens potassium voltage-gated channel subfamily Q member 3 (KCNQ3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017013400.1

ORF Insert Sequence:

ATGACTCAGA GCCAACCAGG AAATGACCCA GTATGCTTGG CTACTTCTGA GAAGCATCCT 
TGTGTGTCTG TGTGGGAAGG GAGAGCAAAC AGAAGCAGGA GGGCCATGGT GGCACAGGCA 
TGGAGGACCT CAATGAGGAA GCAGAGGGAG GAAGCGTGTT TCAGGTTCCT GATTGTCCTG 
GGGTGCTTGA TTCTGGCTGT CCTGACCACA TTCAAGGAGT ATGAGACTGT CTCGGGAGAC 
TGGCTTCTGT TACTGGAGAC ATTTGCTATT TTCATCTTTG GAGCCGAGTT TGCTTTGAGG 
ATCTGGGCTG CTGGATGTTG CTGCCGATAC AAAGGCTGGC GGGGCCGACT GAAGTTTGCC 
AGGAAGCCCC TGTGCATGTT GGACATCTTT GTGCTGATTG CCTCTGTGCC AGTGGTTGCT 
GTGGGAAACC AAGGCAATGT TCTGGCCACC TCCCTGCGAA GCCTGCGCTT CCTGCAGATC 
CTGCGCATGC TGCGGATGGA CCGGAGAGGT GGCACCTGGA AGCTTCTGGG CTCAGCCATC 
TGTGCCCACA GCAAAGAACT CATCACGGCC TGGTACATCG GTTTCCTGAC ACTCATCCTT 
TCTTCATTTC TTGTCTACCT GGTTGAGAAA GACGTCCCAG AGGTGGATGC ACAAGGAGAG 
GAGATGAAAG AGGAGTTTGA GACCTATGCA GATGCCCTGT GGTGGGGCCT GATCACACTG 
GCCACCATTG GCTATGGAGA CAAGACACCC AAAACGTGGG AAGGCCGTCT GATTGCCGCC 
ACCTTTTCCT TAATTGGCGT CTCCTTTTTT GCCCTTCCAG CGGGCATCCT GGGGTCCGGG 
CTGGCCCTCA AGGTGCAGGA GCAACACCGT CAGAAGCACT TTGAGAAAAG GAGGAAGCCA 
GCTGCTGAGC TCATTCAGGC TGCCTGGAGG TATTATGCTA CCAACCCCAA CAGGATTGAC 
CTGGTGGCGA CATGGAGATT TTATGAATCA GTCGTCTCTT TTCCTTTCTT CAGGAAAGAA 
CAGCTGGAGG CAGCATCCAG CCAAAAGCTG GGTCTCTTGG ATCGGGTTCG CCTTTCTAAT 
CCTCGTGGTA GCAATACTAA AGGAAAGCTA TTTACCCCTC TGAATGTAGA TGCCATAGAA 
GAAAGTCCTT CTAAAGAACC AAAGCCTGTT GGCTTAAACA ATAAAGAGCG TTTCCGCACG 
GCCTTCCGCA TGAAAGCCTA CGCTTTCTGG CAGAGTTCTG AAGATGCCGG GACAGGTGAC 
CCCATGGCGG AAGACAGGGG CTATGGGAAT GACTTCCCCA TCGAAGACAT GATCCCCACC 
CTGAAGGCCG CCATCCGAGC CGTCAGAATT CTACAATTCC GTCTCTATAA AAAAAAATTC 
AAGGAGACTT TGAGGCCTTA CGATGTGAAG GATGTGATTG AGCAGTATTC TGCCGGGCAT 
CTCGACATGC TTTCCAGGAT AAAGTACCTT CAGACGAGAA TAGATATGAT TTTCACCCCT 
GGACCTCCCT CCACGCCAAA ACACAAGAAG TCTCAGAAAG GGTCAGCATT CACCTTCCCA 
TCCCAGCAAT CTCCCAGGAA TGAACCATAT GTAGCCAGAC CATCCACATC AGAAATCGAA 
GACCAAAGCA TGATGGGGAA GTTTGTAAAA GTTGAAAGAC AGGTTCAGGA CATGGGGAAG 
AAGCTGGACT TCCTCGTGGA TATGCACATG CAACACATGG AACGGTTGCA GGTGCAGGTC 
ACGGAGTATT ACCCAACCAA GGGCACCTCC TCGCCAGCTG AAGCAGAGAA GAAGGAGGAC 
AACAGGTATT CCGATTTGAA AACCATCATC TGCAACTATT CTGAGACAGG CCCCCCGGAA 
CCACCCTACA GCTTCCACCA GGTGACCATT GACAAAGTCA GCCCCTATGG GTTTTTTGCA 
CATGACCCTG TGAACCTGCC CCGAGGGGGA CCCAGTTCTG GAAAGGTTCA GGCAACTCCT 
CCTTCCTCAG CAACAACGTA TGTGGAGAGG CCCACGGTCC TGCCTATCTT GACTCTTCTC 
GACTCCCGAG TGAGCTGCCA CTCCCAGGCT GACCTGCAGG GCCCCTACTC GGACCGAATC 
TCCCCCCGGC AGAGACGTAG CATCACGCGA GACAGTGACA CACCTCTGTC CCTGATGTCG 
GTCAACCACG AGGAGCTGGA GAGGTCTCCA AGTGGCTTCA GCATCTCCCA GGACAGAGAT 
GATTATGTGT TCGGCCCCAA TGGGGGGTCG AGCTGGATGA GGGAGAAGCG GTACCTCGCC 
GAGGGTGAGA CGGACACAGA CACGGACCCC TTCACGCCCA GCGGCTCCAT GCCTCTGTCG 
TCCACAGGGG ATGGGATTTC TGATTCAGTA TGGACCCCTT CCAATAAGCC CATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Pharmacophore modeling, 3D-QSAR, and in silico ADME prediction of N-pyridyl and pyrimidine benzamides as potent antiepileptic agents.
Journal of receptor and signal transduction research37(3)259-266(2017 Jun)
Malik R,Mehta P,Srivastava S,Choudhary BS,Sharma M

Structural Insights into the M-Channel Proximal C-Terminus/Calmodulin Complex.
Biochemistry55(38)5353-65(2016 09)
Strulovich R,Tobelaim WS,Attali B,Hirsch JA

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KCNQ3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

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