MAMU-A cDNA ORF clone, Macaca mulatta(Rhesus monkey)

Gene
Clones
gRNAs

Summary

Gene Symbol	MAMU-A
Entrez Gene ID	711832
Full Name	major histocompatibility complex, class I, A
Synonyms	MAMU-A1,MAMU-A2
Gene Type	protein-coding
Organism	Macaca mulatta(Rhesus monkey)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001048246.2	NP_001041711.2	major histocompatibility complex, class I, A precursor
XM_028846909.1	XP_028702742.1	major histocompatibility complex, class I, A isoform X1
XM_028846910.1	XP_028702743.1	major histocompatibility complex, class I, A isoform X2

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Suppression of a Natural Killer Cell Response by Simian Immunodeficiency Virus Peptides.
Schafer JL, Ries M, Guha N, Connole M, Colantonio AD, Wiertz EJ, Wilson NA, Kaur A, Evans DT
PLoS pathogens11(9)e1005145(2015 Sep)

A new rhesus macaque assembly and annotation for next-generation sequencing analyses.
Zimin AV, Cornish AS, Maudhoo MD, Gibbs RM, Zhang X, Pandey S, Meehan DT, Wipfler K, Bosinger SE, Johnson ZP, Tharp GK, Mar?ais G, Roberts M, Ferguson B, Fox HS, Treangen T, Salzberg SL, Yorke JA, Norgren RB Jr
Biology direct9(1)20(2014 Oct)

TCR affinity associated with functional differences between dominant and subdominant SIV epitope-specific CD8+ T cells in Mamu-A*01+ rhesus monkeys.
Osuna CE, Gonzalez AM, Chang HH, Hung AS, Ehlinger E, Anasti K, Alam SM, Letvin NL
PLoS pathogens10(4)e1004069(2014 Apr)

Full-length novel MHC class I allele discovery by next-generation sequencing: two platforms are better than one.
Dudley DM, Karl JA, Creager HM, Bohn PS, Wiseman RW, O'Connor DH
Immunogenetics66(1)15-24(2014 Jan)

KIR2DL4 copy number variation is associated with CD4+ T-cell depletion and function of cytokine-producing NK cell subsets in SIV-infected Mamu-A*01-negative rhesus macaques.
Hellmann I, Letvin NL, Schmitz JE
Journal of virology87(9)5305-10(2013 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest SIV (Simian immunodeficiency virus) peptides act as ligands for CD4+ T-Lymphocyte MAMU-A1 (MHC class I antigen) and for natural killer cell immunoglobulin-like receptor KIR3DL05; these interactions appear to assist SIV in immune evasion.
Title: Suppression of a Natural Killer Cell Response by Simian Immunodeficiency Virus Peptides.

TCR affinity associated with functional differences between dominant and subdominant SIV epitope-specific CD8+ T cells in Mamu-A*01+ rhesus monkeys.
Title: TCR affinity associated with functional differences between dominant and subdominant SIV epitope-specific CD8+ T cells in Mamu-A*01+ rhesus monkeys.

Higher KIR2DL4 copy numbers is associated with an increased IFN-gamma production in NK cell subsets in SIV-infected Mamu-A*01-negative rhesus macaques.
Title: KIR2DL4 copy number variation is associated with CD4+ T-cell depletion and function of cytokine-producing NK cell subsets in SIV-infected Mamu-A*01-negative rhesus macaques.

Two alleles expressed with high frequency in Chinese rhesus macaques, Mamu-A1*02601 and Mamu-B*08301 were characterized. These Mamu alleles share peptide-binding characteristics with the HLA-A2 and HLA-A3 supertypes, respectively.
Title: Functional analysis of frequently expressed Chinese rhesus macaque MHC class I molecules Mamu-A1*02601 and Mamu-B*08301 reveals HLA-A2 and HLA-A3 supertypic specificities.

Mamu-A*012 status was associated with significantly more frequent death (P = 0.04) as was TRIM5 alleles 6-11
Title: Contributions of Mamu-A*01 status and TRIM5 allele expression, but not CCL3L copy number variation, to the control of SIVmac251 replication in Indian-origin rhesus monkeys.

The following MAMU-A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAMU-A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMb01966	NM_001048246.2 Latest version!	Macaca mulatta major histocompatibility complex, class I, A (MAMU-A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
OMb83820	XM_028846909.1 Latest version!	Macaca mulatta major histocompatibility complex, class I, A (MAMU-A), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMb83821	XM_028846910.1 Latest version!	Macaca mulatta major histocompatibility complex, class I, A (MAMU-A), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MAMU-A ( NM_001048246.2 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> NP_001041711.2 Macaca mulatta major histocompatibility complex, class I, A (MAMU-A), mRNA.

Price & Availability↑

CloneID	OMb01966
Clone ID Related Accession (Same CDS sequence)	NM_001048246.2
Accession Version	NM_001048246.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1098bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-27
Organism	Macaca mulatta(Rhesus monkey)
Product	major histocompatibility complex, class I, A precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AJ551320.1 and AF157396.1. On Jul 31, 2010 this sequence version replaced NM_001048246.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF157396.1, AF199357.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA27160168, SAMEA27161668 [ECO:0000350] ##Evidence-Data-END##

ATGGCGGTCA TGGCGCCCCG AACCCTCCTC CTGGTGCTCT CCGGGGCCCT GGCCCTGACC 
CAGACCTGGG CGGGCTCGCA CTCCTTGAGA TATTTCTACA CCTCCATGTC CCGGCCCGGC 
CGCGGGCAGC CCCGCTTCAT CTCCGTGGGC TACGTGGACG ACACGCAGTT CGTGCGGTTC 
GACAGCGACG CCGAGAGTCC GAGAGAGGAG CCGCGGGCGC CGTGGATGGA GCAGGAGGGG 
CCGGAGTATT GGGACCAGAA CACACGGATC TGCAAGGCCG ACACACAGAC TCTCCGAGAG 
AACCTGCGGA CCCTGCTCCG CTACTACAAC CAGAGCGAGG CCGGGTCTCA CACCATCCAG 
ACGATGTACG GCTGCGACCT GGGGCCGGAC GGGCGCCTCC TCCGCGGGTA TGACCAGTCC 
GCCTACGACG GCAGGGATTA CATCGCCCTG AACGAGGACC TGCGCTCCTG GACCGCGGCG 
GACATGGCGG CTCAGAACAC CCAGCGGAAG TGGGAGGCGG CGGGTGTGGC GGAGCAGTGG 
AGAGCCTACC TGGAGGGCGA GTGCCTGGAG TGGCTCCGCA GACACCTGGA GAACGGGAAG 
GAGACGCTGC AGCGCGCGGA CTCCCCCAAG ACACATGTGA CCCACCACCC CGTCTCTGAC 
CATGAGGCCA CCCTGAGGTG CTGGGCCCTG GGCTTCTACC CTGCGGAGAT CACACTGACC 
TGGCGGCGGG ATGGGGAGGA CCAAACTCAG GACACGGAGC TCGTGGAGAC CAGGCCTGCA 
GGAGATGGAA CCTTCCAGAA GTGGGCGGCT GTGGTGGTGC CTTCTGGAAA GGAGCAGAGA 
TACACCTGTC ATGTGCAGCA TGAGGGTCTG CCCGAGCCCC TCACCCTGAG ATGGGAGCCG 
TCTTCCCAGT CAACCATCCC CATCGTGGGC ATCATTGCTG GCCTGGTTCT CCTTGGAACT 
GTGGTCACTG GAGCTGTGGT CGCTGCTGTG ATGTGGAGGA GGAAGAGCTC AGATAGAAAA 
GGAGGAAGCT ACTCTCAGGC TGCAAGCAGT GACAGTGCCC AGGGATCTGA TGTGTCTCTT 
ACGGCTTGTA AAGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001041711.2
CDS	1..1098
Translation	MAVMAPRTLLLVLSGALALTQTWAGSHSLRYFYTSMSRPGRGQPRFISVGYVDDTQFVRFDSDAESPREEPRAPWMEQEGPEYWDQNTRICKADTQTLRENLRTLLRYYNQSEAGSHTIQTMYGCDLGPDGRLLRGYDQSAYDGRDYIALNEDLRSWTAADMAAQNTQRKWEAAGVAEQWRAYLEGECLEWLRRHLENGKETLQRADSPKTHVTHHPVSDHEATLRCWALGFYPAEITLTWRRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGKEQRYTCHVQHEGLPEPLTLRWEPSSQSTIPIVGIIAGLVLLGTVVTGAVVAAVMWRRKSSDRKGGSYSQAASSDSAQGSDVSLTACKV

Target ORF information:

RefSeq Version	NM_001048246.2
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta major histocompatibility complex, class I, A (MAMU-A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001048246.2

ORF Insert Sequence:

ATGGCGGTCA TGGCGCCCCG AACCCTCCTC CTGGTGCTCT CCGGGGCCCT GGCCCTGACC 
CAGACCTGGG CGGGCTCGCA CTCCTTGAGA TATTTCTACA CCTCCATGTC CCGGCCCGGC 
CGCGGGCAGC CCCGCTTCAT CTCCGTGGGC TACGTGGACG ACACGCAGTT CGTGCGGTTC 
GACAGCGACG CCGAGAGTCC GAGAGAGGAG CCGCGGGCGC CGTGGATGGA GCAGGAGGGG 
CCGGAGTATT GGGACCAGAA CACACGGATC TGCAAGGCCG ACACACAGAC TCTCCGAGAG 
AACCTGCGGA CCCTGCTCCG CTACTACAAC CAGAGCGAGG CCGGGTCTCA CACCATCCAG 
ACGATGTACG GCTGCGACCT GGGGCCGGAC GGGCGCCTCC TCCGCGGGTA TGACCAGTCC 
GCCTACGACG GCAGGGATTA CATCGCCCTG AACGAGGACC TGCGCTCCTG GACCGCGGCG 
GACATGGCGG CTCAGAACAC CCAGCGGAAG TGGGAGGCGG CGGGTGTGGC GGAGCAGTGG 
AGAGCCTACC TGGAGGGCGA GTGCCTGGAG TGGCTCCGCA GACACCTGGA GAACGGGAAG 
GAGACGCTGC AGCGCGCGGA CTCCCCCAAG ACACATGTGA CCCACCACCC CGTCTCTGAC 
CATGAGGCCA CCCTGAGGTG CTGGGCCCTG GGCTTCTACC CTGCGGAGAT CACACTGACC 
TGGCGGCGGG ATGGGGAGGA CCAAACTCAG GACACGGAGC TCGTGGAGAC CAGGCCTGCA 
GGAGATGGAA CCTTCCAGAA GTGGGCGGCT GTGGTGGTGC CTTCTGGAAA GGAGCAGAGA 
TACACCTGTC ATGTGCAGCA TGAGGGTCTG CCCGAGCCCC TCACCCTGAG ATGGGAGCCG 
TCTTCCCAGT CAACCATCCC CATCGTGGGC ATCATTGCTG GCCTGGTTCT CCTTGGAACT 
GTGGTCACTG GAGCTGTGGT CGCTGCTGTG ATGTGGAGGA GGAAGAGCTC AGATAGAAAA 
GGAGGAAGCT ACTCTCAGGC TGCAAGCAGT GACAGTGCCC AGGGATCTGA TGTGTCTCTT 
ACGGCTTGTA AAGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAMU-A ( XM_028846909.1 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> XP_028702742.1 Macaca mulatta major histocompatibility complex, class I, A (MAMU-A), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMb83820
Clone ID Related Accession (Same CDS sequence)	XM_028846909.1
Accession Version	XM_028846909.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1185bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-25
Organism	Macaca mulatta(Rhesus monkey)
Product	major histocompatibility complex, class I, A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041757.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGTCA TGGCGCCCCG AACCCTCCTC CTGGTGCTCT CAGGGGTCCT GGCCCTGACC 
CAGACCCGGG CGGGCTCGCA CTCCATGAGC TATTTCTACA CCTACATGTC CCGGCCCGGC 
CGCGGGGAGC CCCGCTTCGT CGCCGTGGGC TACGTGGACG ACACGCAGTT CGTGCGGTTC 
GACAGCGACG CCGCGAGCCA GAGGATGGAG CCGCGGGCGC CGTGGGTGGA GCAGGAGGGG 
CCGGAGTATT GGGACCGGGA GACACGGATC ATGAAGACCG AGACACAGAA TGCCCCAGTG 
GCCCTGCGGA ACCTGCGCGG CTACTACAAC CAGAGCGAGG CCGGGTCTCA CACCTACCAG 
GTGATGTACG GCTGCGACCT GGGGCCCGAC GGGCGCCTCC TCCGCGGGTA TGAACAGTTC 
GCCTACGACG GCAAGGATTA CATCGCCCTG AACGACGACC TGCGTTCCTG GACAGCCGCG 
GACTTGGCGG CTCAGAACAC CCAGCGGAAG TGGGAGGCGG CGGGTGTGGC GGAGCAGCAC 
AGAACCTACC TGGAGGGCGA GTGCCTGGAG TGGCTCCGCA GATACCTGGA GAACGGGAAG 
GAGACGCTGC AGCGCGCGGA CCCCCCCAAG ACACATGTGA CCCACCACCC CGTCTCTGAC 
TATGAGGCCA CCCTGAGGTG CTGGGCCCTG GGCTTCTACC CTGCGGAGAT CACACTGACC 
TGGCAGCGGG ACGGGGAGGA CCAAACTCAG GACACGGAGC TTGTGGAGAC CAGGCCTGCA 
GGAGATGGAA CCTTCCAGAA GTGGGCGGCT GTGGTTGTGC CTTCTGGAAA AGAGCATAGA 
TACACCTGTC ATGTGCAGCA TGAGGGTCTG CCCGAGCCCC TCACCTTGAG ATGGGAGCCG 
TCTTCCCAGT CCACCATCCC CATCGTGGGC ATCATTGCTG GCCTGGTTCT GCTTGGAGCT 
GTGGTCACTG GAGCTGTGGT TGCTGTTGTG ATGTGGAGGA GGAAGAGCTC AGATAGAAAA 
GGAGGGAGCT ACTCTCAGGC TGCAAGCAGT GACAGTGCCC AGGGCTCTGA TGTGTCTCTC 
ACAGCTTGTA AAGGTGAGAT CCTGGGGGGC CTGATGTGTG GGGGGTGTTG GAGGGAACAG 
TGGACGCAGC TGTGCTGTGG GGTTTCTTTG ACTTGGATGT ATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_028702742.1
CDS	344..1528
Translation	MAVMAPRTLLLVLSGVLALTQTRAGSHSMSYFYTYMSRPGRGEPRFVAVGYVDDTQFVRFDSDAASQRMEPRAPWVEQEGPEYWDRETRIMKTETQNAPVALRNLRGYYNQSEAGSHTYQVMYGCDLGPDGRLLRGYEQFAYDGKDYIALNDDLRSWTAADLAAQNTQRKWEAAGVAEQHRTYLEGECLEWLRRYLENGKETLQRADPPKTHVTHHPVSDYEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGKEHRYTCHVQHEGLPEPLTLRWEPSSQSTIPIVGIIAGLVLLGAVVTGAVVAVVMWRRKSSDRKGGSYSQAASSDSAQGSDVSLTACKGEILGGLMCGGCWREQWTQLCCGVSLTWMY

Target ORF information:

RefSeq Version	XM_028846909.1
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta major histocompatibility complex, class I, A (MAMU-A), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_028846909.1

ORF Insert Sequence:

ATGGCGGTCA TGGCGCCCCG AACCCTCCTC CTGGTGCTCT CAGGGGTCCT GGCCCTGACC 
CAGACCCGGG CGGGCTCGCA CTCCATGAGC TATTTCTACA CCTACATGTC CCGGCCCGGC 
CGCGGGGAGC CCCGCTTCGT CGCCGTGGGC TACGTGGACG ACACGCAGTT CGTGCGGTTC 
GACAGCGACG CCGCGAGCCA GAGGATGGAG CCGCGGGCGC CGTGGGTGGA GCAGGAGGGG 
CCGGAGTATT GGGACCGGGA GACACGGATC ATGAAGACCG AGACACAGAA TGCCCCAGTG 
GCCCTGCGGA ACCTGCGCGG CTACTACAAC CAGAGCGAGG CCGGGTCTCA CACCTACCAG 
GTGATGTACG GCTGCGACCT GGGGCCCGAC GGGCGCCTCC TCCGCGGGTA TGAACAGTTC 
GCCTACGACG GCAAGGATTA CATCGCCCTG AACGACGACC TGCGTTCCTG GACAGCCGCG 
GACTTGGCGG CTCAGAACAC CCAGCGGAAG TGGGAGGCGG CGGGTGTGGC GGAGCAGCAC 
AGAACCTACC TGGAGGGCGA GTGCCTGGAG TGGCTCCGCA GATACCTGGA GAACGGGAAG 
GAGACGCTGC AGCGCGCGGA CCCCCCCAAG ACACATGTGA CCCACCACCC CGTCTCTGAC 
TATGAGGCCA CCCTGAGGTG CTGGGCCCTG GGCTTCTACC CTGCGGAGAT CACACTGACC 
TGGCAGCGGG ACGGGGAGGA CCAAACTCAG GACACGGAGC TTGTGGAGAC CAGGCCTGCA 
GGAGATGGAA CCTTCCAGAA GTGGGCGGCT GTGGTTGTGC CTTCTGGAAA AGAGCATAGA 
TACACCTGTC ATGTGCAGCA TGAGGGTCTG CCCGAGCCCC TCACCTTGAG ATGGGAGCCG 
TCTTCCCAGT CCACCATCCC CATCGTGGGC ATCATTGCTG GCCTGGTTCT GCTTGGAGCT 
GTGGTCACTG GAGCTGTGGT TGCTGTTGTG ATGTGGAGGA GGAAGAGCTC AGATAGAAAA 
GGAGGGAGCT ACTCTCAGGC TGCAAGCAGT GACAGTGCCC AGGGCTCTGA TGTGTCTCTC 
ACAGCTTGTA AAGGTGAGAT CCTGGGGGGC CTGATGTGTG GGGGGTGTTG GAGGGAACAG 
TGGACGCAGC TGTGCTGTGG GGTTTCTTTG ACTTGGATGT ATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAMU-A ( XM_028846910.1 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> XP_028702743.1 Macaca mulatta major histocompatibility complex, class I, A (MAMU-A), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMb83821
Clone ID Related Accession (Same CDS sequence)	XM_028846910.1
Accession Version	XM_028846910.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1098bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-25
Organism	Macaca mulatta(Rhesus monkey)
Product	major histocompatibility complex, class I, A isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041757.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGTCA TGGCGCCCCG AACCCTCCTC CTGGTGCTCT CAGGGGTCCT GGCCCTGACC 
CAGACCCGGG CGGGCTCGCA CTCCATGAGC TATTTCTACA CCTACATGTC CCGGCCCGGC 
CGCGGGGAGC CCCGCTTCGT CGCCGTGGGC TACGTGGACG ACACGCAGTT CGTGCGGTTC 
GACAGCGACG CCGCGAGCCA GAGGATGGAG CCGCGGGCGC CGTGGGTGGA GCAGGAGGGG 
CCGGAGTATT GGGACCGGGA GACACGGATC ATGAAGACCG AGACACAGAA TGCCCCAGTG 
GCCCTGCGGA ACCTGCGCGG CTACTACAAC CAGAGCGAGG CCGGGTCTCA CACCTACCAG 
GTGATGTACG GCTGCGACCT GGGGCCCGAC GGGCGCCTCC TCCGCGGGTA TGAACAGTTC 
GCCTACGACG GCAAGGATTA CATCGCCCTG AACGACGACC TGCGTTCCTG GACAGCCGCG 
GACTTGGCGG CTCAGAACAC CCAGCGGAAG TGGGAGGCGG CGGGTGTGGC GGAGCAGCAC 
AGAACCTACC TGGAGGGCGA GTGCCTGGAG TGGCTCCGCA GATACCTGGA GAACGGGAAG 
GAGACGCTGC AGCGCGCGGA CCCCCCCAAG ACACATGTGA CCCACCACCC CGTCTCTGAC 
TATGAGGCCA CCCTGAGGTG CTGGGCCCTG GGCTTCTACC CTGCGGAGAT CACACTGACC 
TGGCAGCGGG ACGGGGAGGA CCAAACTCAG GACACGGAGC TTGTGGAGAC CAGGCCTGCA 
GGAGATGGAA CCTTCCAGAA GTGGGCGGCT GTGGTTGTGC CTTCTGGAAA AGAGCATAGA 
TACACCTGTC ATGTGCAGCA TGAGGGTCTG CCCGAGCCCC TCACCTTGAG ATGGGAGCCG 
TCTTCCCAGT CCACCATCCC CATCGTGGGC ATCATTGCTG GCCTGGTTCT GCTTGGAGCT 
GTGGTCACTG GAGCTGTGGT TGCTGTTGTG ATGTGGAGGA GGAAGAGCTC AGATAGAAAA 
GGAGGGAGCT ACTCTCAGGC TGCAAGCAGT GACAGTGCCC AGGGCTCTGA TGTGTCTCTC 
ACAGCTTGTA AAGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_028702743.1
CDS	344..1441
Translation	MAVMAPRTLLLVLSGVLALTQTRAGSHSMSYFYTYMSRPGRGEPRFVAVGYVDDTQFVRFDSDAASQRMEPRAPWVEQEGPEYWDRETRIMKTETQNAPVALRNLRGYYNQSEAGSHTYQVMYGCDLGPDGRLLRGYEQFAYDGKDYIALNDDLRSWTAADLAAQNTQRKWEAAGVAEQHRTYLEGECLEWLRRYLENGKETLQRADPPKTHVTHHPVSDYEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGKEHRYTCHVQHEGLPEPLTLRWEPSSQSTIPIVGIIAGLVLLGAVVTGAVVAVVMWRRKSSDRKGGSYSQAASSDSAQGSDVSLTACKV

Target ORF information:

RefSeq Version	XM_028846910.1
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta major histocompatibility complex, class I, A (MAMU-A), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_028846910.1

ORF Insert Sequence:

ATGGCGGTCA TGGCGCCCCG AACCCTCCTC CTGGTGCTCT CAGGGGTCCT GGCCCTGACC 
CAGACCCGGG CGGGCTCGCA CTCCATGAGC TATTTCTACA CCTACATGTC CCGGCCCGGC 
CGCGGGGAGC CCCGCTTCGT CGCCGTGGGC TACGTGGACG ACACGCAGTT CGTGCGGTTC 
GACAGCGACG CCGCGAGCCA GAGGATGGAG CCGCGGGCGC CGTGGGTGGA GCAGGAGGGG 
CCGGAGTATT GGGACCGGGA GACACGGATC ATGAAGACCG AGACACAGAA TGCCCCAGTG 
GCCCTGCGGA ACCTGCGCGG CTACTACAAC CAGAGCGAGG CCGGGTCTCA CACCTACCAG 
GTGATGTACG GCTGCGACCT GGGGCCCGAC GGGCGCCTCC TCCGCGGGTA TGAACAGTTC 
GCCTACGACG GCAAGGATTA CATCGCCCTG AACGACGACC TGCGTTCCTG GACAGCCGCG 
GACTTGGCGG CTCAGAACAC CCAGCGGAAG TGGGAGGCGG CGGGTGTGGC GGAGCAGCAC 
AGAACCTACC TGGAGGGCGA GTGCCTGGAG TGGCTCCGCA GATACCTGGA GAACGGGAAG 
GAGACGCTGC AGCGCGCGGA CCCCCCCAAG ACACATGTGA CCCACCACCC CGTCTCTGAC 
TATGAGGCCA CCCTGAGGTG CTGGGCCCTG GGCTTCTACC CTGCGGAGAT CACACTGACC 
TGGCAGCGGG ACGGGGAGGA CCAAACTCAG GACACGGAGC TTGTGGAGAC CAGGCCTGCA 
GGAGATGGAA CCTTCCAGAA GTGGGCGGCT GTGGTTGTGC CTTCTGGAAA AGAGCATAGA 
TACACCTGTC ATGTGCAGCA TGAGGGTCTG CCCGAGCCCC TCACCTTGAG ATGGGAGCCG 
TCTTCCCAGT CCACCATCCC CATCGTGGGC ATCATTGCTG GCCTGGTTCT GCTTGGAGCT 
GTGGTCACTG GAGCTGTGGT TGCTGTTGTG ATGTGGAGGA GGAAGAGCTC AGATAGAAAA 
GGAGGGAGCT ACTCTCAGGC TGCAAGCAGT GACAGTGCCC AGGGCTCTGA TGTGTCTCTC 
ACAGCTTGTA AAGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Suppression of a Natural Killer Cell Response by Simian Immunodeficiency Virus Peptides.
PLoS pathogens11(9)e1005145(2015 Sep)
Schafer JL,Ries M,Guha N,Connole M,Colantonio AD,Wiertz EJ,Wilson NA,Kaur A,Evans DT

A new rhesus macaque assembly and annotation for next-generation sequencing analyses.
Biology direct9(1)20(2014 Oct)
Zimin AV,Cornish AS,Maudhoo MD,Gibbs RM,Zhang X,Pandey S,Meehan DT,Wipfler K,Bosinger SE,Johnson ZP,Tharp GK,Mar?ais G,Roberts M,Ferguson B,Fox HS,Treangen T,Salzberg SL,Yorke JA,Norgren RB Jr

TCR affinity associated with functional differences between dominant and subdominant SIV epitope-specific CD8+ T cells in Mamu-A*01+ rhesus monkeys.
PLoS pathogens10(4)e1004069(2014 Apr)
Osuna CE,Gonzalez AM,Chang HH,Hung AS,Ehlinger E,Anasti K,Alam SM,Letvin NL

Full-length novel MHC class I allele discovery by next-generation sequencing: two platforms are better than one.
Immunogenetics66(1)15-24(2014 Jan)
Dudley DM,Karl JA,Creager HM,Bohn PS,Wiseman RW,O'Connor DH

KIR2DL4 copy number variation is associated with CD4+ T-cell depletion and function of cytokine-producing NK cell subsets in SIV-infected Mamu-A*01-negative rhesus macaques.
Journal of virology87(9)5305-10(2013 May)
Hellmann I,Letvin NL,Schmitz JE

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MAMU-A cDNA ORF clone, Macaca mulatta(Rhesus monkey)

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