Gene Symbol | TLR2 |
Entrez Gene ID | 574290 |
Full Name | toll like receptor 2 |
Gene Type | protein-coding |
Organism | Macaca mulatta(Rhesus monkey) |
ORF » Species Summary » Macaca mulatta » TLR2 cDNA ORF clone
Gene Symbol | TLR2 |
Entrez Gene ID | 574290 |
Full Name | toll like receptor 2 |
Gene Type | protein-coding |
Organism | Macaca mulatta(Rhesus monkey) |
mRNA | Protein | Name |
---|---|---|
XM_015139352.1 | XP_014994838.1 | toll-like receptor 2 isoform X1 |
NM_001130425.1 | NP_001123897.1 | toll-like receptor 2 precursor |
XM_015139351.2 | XP_014994837.2 | toll-like receptor 2 isoform X1 |
XM_015139351.1 | XP_014994837.1 | toll-like receptor 2 isoform X1 |
XM_015139352.2 | XP_014994838.2 | toll-like receptor 2 isoform X1 |
Pan troglodytes (chimpanzee) | TLR2 | NP_001123941.1 |
Gallus gallus (chicken) | LOC100858824 | XP_004940943.1 |
Gallus gallus (chicken) | TLR2-2 | NP_001155122.1 |
Gallus gallus (chicken) | TLR2-1 | NP_989609.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100485927 | XP_002933538.2 |
Homo sapiens (human) | TLR2 | NP_003255.2 |
Canis lupus familiaris (dog) | TLR2 | NP_001005264.2 |
Bos taurus (cattle) | TLR2 | NP_776622.1 |
Rattus norvegicus (Norway rat) | Tlr2 | NP_942064.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100485771 | XP_002933537.1 |
Mus musculus (house mouse) | Tlr2 | NP_036035.3 |
Danio rerio (zebrafish) | tlr2 | NP_997977.1 |
TLR2 | NP_001123897.1 |
Soluble TLR2 and 4 concentrations in cerebrospinal fluid in HIV/SIV-related neuropathological conditions.
Mothapo KM, Ten Oever J, Koopmans P, Stelma FF, Burm S, Bajramovic J, Verbeek MM, Rikkert MGO, Netea MG, Koopman G, van der Ven AJ
Journal of neurovirology23(2)250-259(2017 Apr)
Positive selection of Toll-like receptor 2 polymorphisms in two closely related old world monkey species, rhesus and Japanese macaques.
Takaki A, Yamazaki A, Maekawa T, Shibata H, Hirayama K, Kimura A, Hirai H, Yasunami M
Immunogenetics64(1)15-29(2012 Jan)
Natural selection in the TLR-related genes in the course of primate evolution.
Nakajima T, Ohtani H, Satta Y, Uno Y, Akari H, Ishida T, Kimura A
Immunogenetics60(12)727-35(2008 Dec)
Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections.
Mandl JN, Barry AP, Vanderford TH, Kozyr N, Chavan R, Klucking S, Barrat FJ, Coffman RL, Staprans SI, Feinberg MB
Nature medicine14(10)1077-87(2008 Oct)
Toll-like receptors: insights into their possible role in the pathogenesis of lyme neuroborreliosis.
Bernardino AL, Myers TA, Alvarez X, Hasegawa A, Philipp MT
Infection and immunity76(10)4385-95(2008 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
TLR2 of M. fuscata has undergone purifying selection while the membrane-proximal part of the extracellular domain of M. mulatta TLR2 exhibits higher rates of non-synonymous substitutions, indicating a trace of Darwinian positive selection
Title: Positive selection of Toll-like receptor 2 polymorphisms in two closely related old world monkey species, rhesus and Japanese macaques.
The results indicate that microglia and astrocytes respond to B. burgdorferi through TLR1/2 and TLR5.
Title: Toll-like receptors: insights into their possible role in the pathogenesis of lyme neuroborreliosis.
The following TLR2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TLR2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMb04683 | |
Clone ID Related Accession (Same CDS sequence) | NM_001130425.1 | |
Accession Version | NM_001130425.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2355bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-17 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | toll-like receptor 2 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB445630.1. On Jul 24, 2008 this sequence version replaced XM_001087830.1. ##Evidence-Data-START## Transcript is intronless :: AB445630.1 [ECO:0000345] ##Evidence-Data-END## |
1 | ATGCCACATA CTTTGTGGAT GGTGTGGGTC TTGGGAGTCA TCATCAGCCT CTCCAAGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001123897.1 |
CDS | 1..2355 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001130425.1 |
1 | ATGCCACATA CTTTGTGGAT GGTGTGGGTC TTGGGAGTCA TCATCAGCCT CTCCAAGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb34170 | |
Clone ID Related Accession (Same CDS sequence) | XM_015139352.1 , XM_015139351.1 | |
Accession Version | XM_015139352.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2355bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-12-20 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | toll-like receptor 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014804902.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Macaca mulatta Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCACATA CTTTGTGGAT GGTGTGGGTC TTGGGAGTCA TCATCAGCCT CTCCAAGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_014994838.1 |
CDS | 99..2453 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015139352.1 |
1 | ATGCCACATA CTTTGTGGAT GGTGTGGGTC TTGGGAGTCA TCATCAGCCT CTCCAAGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb34170 | |
Clone ID Related Accession (Same CDS sequence) | XM_015139352.1 , XM_015139351.1 | |
Accession Version | XM_015139351.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2355bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-12-20 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | toll-like receptor 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014804902.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Macaca mulatta Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCACATA CTTTGTGGAT GGTGTGGGTC TTGGGAGTCA TCATCAGCCT CTCCAAGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_014994837.1 |
CDS | 223..2577 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015139351.1 |
1 | ATGCCACATA CTTTGTGGAT GGTGTGGGTC TTGGGAGTCA TCATCAGCCT CTCCAAGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb85293 | |
Clone ID Related Accession (Same CDS sequence) | XM_015139351.2 , XM_015139352.2 | |
Accession Version | XM_015139351.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2355bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-25 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | toll-like receptor 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041758.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 23, 2019 this sequence version replaced XM_015139351.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCACATA CTTTGTGGAT GGTGTGGGTC TTGGGAGTCA TCATCAGCCT CTCCAAGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_014994837.2 |
CDS | 214..2568 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015139351.2 |
1 | ATGCCACATA CTTTGTGGAT GGTGTGGGTC TTGGGAGTCA TCATCAGCCT CTCCAAGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMb85293 | |
Clone ID Related Accession (Same CDS sequence) | XM_015139351.2 , XM_015139352.2 | |
Accession Version | XM_015139352.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2355bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-25 | |
Organism | Macaca mulatta(Rhesus monkey) | |
Product | toll-like receptor 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041758.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 23, 2019 this sequence version replaced XM_015139352.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCACATA CTTTGTGGAT GGTGTGGGTC TTGGGAGTCA TCATCAGCCT CTCCAAGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_014994838.2 |
CDS | 98..2452 |
Translation |
Target ORF information:
Target ORF information:
|
XM_015139352.2 |
1 | ATGCCACATA CTTTGTGGAT GGTGTGGGTC TTGGGAGTCA TCATCAGCCT CTCCAAGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Soluble TLR2 and 4 concentrations in cerebrospinal fluid in HIV/SIV-related neuropathological conditions. |
Positive selection of Toll-like receptor 2 polymorphisms in two closely related old world monkey species, rhesus and Japanese macaques. |
Natural selection in the TLR-related genes in the course of primate evolution. |
Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections. |
Toll-like receptors: insights into their possible role in the pathogenesis of lyme neuroborreliosis. |