IL18 cDNA ORF clone, Macaca mulatta(Rhesus monkey)

Gene
Clones
gRNAs

Summary

Gene Symbol	IL18
Entrez Gene ID	574151
Full Name	interleukin 18
Gene Type	protein-coding
Organism	Macaca mulatta(Rhesus monkey)

mRNA and Protein(s)

mRNA	Protein	Name
XM_015115662.1	XP_014971148.1	interleukin-18 isoform X1
XM_015115663.1	XP_014971149.1	interleukin-18 isoform X2
NM_001032834.2	NP_001028006.1	interleukin-18
XM_015115663.2	XP_014971149.1	interleukin-18 isoform X2
XM_015115661.2	XP_014971147.1	interleukin-18 isoform X1
XM_015115661.1	XP_014971147.1	interleukin-18 isoform X1
XM_015115662.2	XP_014971148.1	interleukin-18 isoform X1

Pathways from BioSystems

Homologies

	IL18	NP_001028006.1
Mus musculus (house mouse)	Il18	NP_032386.1
Homo sapiens (human)	IL18	NP_001553.1
Canis lupus familiaris (dog)	IL18	NP_001003169.1
Pan troglodytes (chimpanzee)	IL18	XP_003952084.1
Bos taurus (cattle)	IL18	NP_776516.1
Rattus norvegicus (Norway rat)	Il18	NP_062038.1

Gene Ontology
Bibliography

Related articles in PubMed

Urine Interleukin-18 (IL-18) as a Biomarker of Total-Body Irradiation: A Preliminary Study in Nonhuman Primates.
Xiao M, Bolduc DL, Li X, Cui W, Hieber KP, B?nger R, Ossetrova NI
Radiation research188(3)325-334(2017 09)

A new rhesus macaque assembly and annotation for next-generation sequencing analyses.
Zimin AV, Cornish AS, Maudhoo MD, Gibbs RM, Zhang X, Pandey S, Meehan DT, Wipfler K, Bosinger SE, Johnson ZP, Tharp GK, Mar?ais G, Roberts M, Ferguson B, Fox HS, Treangen T, Salzberg SL, Yorke JA, Norgren RB Jr
Biology direct9(1)20(2014 Oct)

AIDS progression is associated with the emergence of IL-17-producing cells early after simian immunodeficiency virus infection.
Campillo-Gimenez L, Cumont MC, Fay M, Kared H, Monceaux V, Diop O, M?ller-Trutwin M, Hurtrel B, L?vy Y, Zaunders J, Dy M, Leite-de-Moraes MC, Elbim C, Estaquier J
Journal of immunology (Baltimore, Md. : 1950)184(2)984-92(2010 Jan)

Interleukin-18 predicts atherosclerosis progression in SIV-infected and uninfected rhesus monkeys (Macaca mulatta) on a high-fat/high-cholesterol diet.
Yearley JH, Xia D, Pearson CB, Carville A, Shannon RP, Mansfield KG
Laboratory investigation; a journal of technical methods and pathology89(6)657-67(2009 Jun)

Expression of the interleukin-18 gene from rhesus macaque by the simian immunodeficiency virus does not result in increased viral replication.
Giavedoni LD, Imhoof JD, Velasquillo MC, Parodi LM, Hodara VL
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research21(3)173-80(2001 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Urine IL-18 measurement, as an early prognostic indicator of survival, may facilitate rapid detection of lethal doses of radiation, based on the currently available data set.
Title: Urine Interleukin-18 (IL-18) as a Biomarker of Total-Body Irradiation: A Preliminary Study in Nonhuman Primates.

SIV infection of rhesus macaques results in the emergence of IL-17-expressing cells during the acute phase. This subpopulation appears at day 14 postinfection concomitantly with an increase in TGF-beta and IL-18 expression.
Title: AIDS progression is associated with the emergence of IL-17-producing cells early after simian immunodeficiency virus infection.

The chronically elevated IL-18 levels seen in later stages of HIV infection may contribute significantly to accelerated atherogenesis in this population.
Title: Interleukin-18 predicts atherosclerosis progression in SIV-infected and uninfected rhesus monkeys (Macaca mulatta) on a high-fat/high-cholesterol diet.

The following IL18 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL18 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMb00169	NM_001032834.2 Latest version!	Macaca mulatta interleukin 18 (IL18), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OMb00169	XM_015115662.2 Latest version!	Macaca mulatta interleukin 18 (IL18), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OMb00169	XM_015115661.2 Latest version!	Macaca mulatta interleukin 18 (IL18), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OMb47808	XM_015115663.2 Latest version!	Macaca mulatta interleukin 18 (IL18), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$104.30 $149.00
View Old Accession Versions >>
OMb47808	XM_015115663.1	Macaca mulatta interleukin 18 (IL18), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$104.30 $149.00
OMb00169	XM_015115661.1	Macaca mulatta interleukin 18 (IL18), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OMb00169	XM_015115662.1	Macaca mulatta interleukin 18 (IL18), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IL18 ( NM_001032834.2 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> NP_001028006.1 Macaca mulatta interleukin 18 (IL18), mRNA.

Price & Availability↑

CloneID	OMb00169
Clone ID Related Accession (Same CDS sequence)	XM_015115662.1 , NM_001032834.2 , XM_015115661.2 , XM_015115661.1 , XM_015115662.2
Accession Version	NM_001032834.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-28
Organism	Macaca mulatta(Rhesus monkey)
Product	interleukin-18
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF303732.1. On Aug 31, 2012 this sequence version replaced NM_001032834.1. ##Evidence-Data-START## Transcript exon combination :: AF303732.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4688315, SAMEA4688316 [ECO:0000348] ##Evidence-Data-END##

ATGGCTGCTG AACCAGCAGA AGACAATTGC ATCAATTTTG TGGCAATGAA ATTTATTGAC 
AGTACGCTTT ACTTTATAGC TGAAGATGAT GAAAACCTGG AATCAGATTA CTTTGGCAAG 
CTTGAATCTA AATTATCAAT CATAAGAAAT TTGAATGACC AAGTTCTCTT CATTGACCAA 
GGAAATCGGC CCCTATTTGA AGATATGACT GATTCTGACT GTAGAGATAA TGCACCCCGG 
ACCATATTTA TTATAAATAT GTATAAAGAT AGCCAGCCTA GAGGTATGGC TGTAGCCATC 
TCTGTGAAAT GTGAGAAAAT TTCAACTCTC TCCTGTGAGA ACAGAATTAT TTCCTTTAAG 
GAAATGAATC CTCCTGATAA CATCAAGGAT ACGAAAAGTG ACATCATATT CTTTCAGAGA 
AGTGTCCCAG GACATGATAA TAAGATGCAA TTTGAATCTT CATCATACGA AGGATACTTT 
CTAGCTTGTG AAAAAGAGAG AGACCTTTAT AAACTCATTT TGAAAAAAAA GGATGAATTG 
GGGGATAGAT CTATAATGTT CACTGTTCAA AACGAAGACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001028006.1
CDS	1..582
Translation	MAAEPAEDNCINFVAMKFIDSTLYFIAEDDENLESDYFGKLESKLSIIRNLNDQVLFIDQGNRPLFEDMTDSDCRDNAPRTIFIINMYKDSQPRGMAVAISVKCEKISTLSCENRIISFKEMNPPDNIKDTKSDIIFFQRSVPGHDNKMQFESSSYEGYFLACEKERDLYKLILKKKDELGDRSIMFTVQNED

Target ORF information:

RefSeq Version	NM_001032834.2
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta interleukin 18 (IL18), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001032834.2

ORF Insert Sequence:

ATGGCTGCTG AACCAGCAGA AGACAATTGC ATCAATTTTG TGGCAATGAA ATTTATTGAC 
AGTACGCTTT ACTTTATAGC TGAAGATGAT GAAAACCTGG AATCAGATTA CTTTGGCAAG 
CTTGAATCTA AATTATCAAT CATAAGAAAT TTGAATGACC AAGTTCTCTT CATTGACCAA 
GGAAATCGGC CCCTATTTGA AGATATGACT GATTCTGACT GTAGAGATAA TGCACCCCGG 
ACCATATTTA TTATAAATAT GTATAAAGAT AGCCAGCCTA GAGGTATGGC TGTAGCCATC 
TCTGTGAAAT GTGAGAAAAT TTCAACTCTC TCCTGTGAGA ACAGAATTAT TTCCTTTAAG 
GAAATGAATC CTCCTGATAA CATCAAGGAT ACGAAAAGTG ACATCATATT CTTTCAGAGA 
AGTGTCCCAG GACATGATAA TAAGATGCAA TTTGAATCTT CATCATACGA AGGATACTTT 
CTAGCTTGTG AAAAAGAGAG AGACCTTTAT AAACTCATTT TGAAAAAAAA GGATGAATTG 
GGGGATAGAT CTATAATGTT CACTGTTCAA AACGAAGACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IL18 ( XM_015115662.1 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> XP_014971148.1 Macaca mulatta interleukin 18 (IL18), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMb00169
Clone ID Related Accession (Same CDS sequence)	XM_015115662.1 , NM_001032834.2 , XM_015115661.2 , XM_015115661.1 , XM_015115662.2
Accession Version	XM_015115662.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-12-20
Organism	Macaca mulatta(Rhesus monkey)
Product	interleukin-18 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014805472.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Macaca mulatta Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGCTG AACCAGCAGA AGACAATTGC ATCAATTTTG TGGCAATGAA ATTTATTGAC 
AGTACGCTTT ACTTTATAGC TGAAGATGAT GAAAACCTGG AATCAGATTA CTTTGGCAAG 
CTTGAATCTA AATTATCAAT CATAAGAAAT TTGAATGACC AAGTTCTCTT CATTGACCAA 
GGAAATCGGC CCCTATTTGA AGATATGACT GATTCTGACT GTAGAGATAA TGCACCCCGG 
ACCATATTTA TTATAAATAT GTATAAAGAT AGCCAGCCTA GAGGTATGGC TGTAGCCATC 
TCTGTGAAAT GTGAGAAAAT TTCAACTCTC TCCTGTGAGA ACAGAATTAT TTCCTTTAAG 
GAAATGAATC CTCCTGATAA CATCAAGGAT ACGAAAAGTG ACATCATATT CTTTCAGAGA 
AGTGTCCCAG GACATGATAA TAAGATGCAA TTTGAATCTT CATCATACGA AGGATACTTT 
CTAGCTTGTG AAAAAGAGAG AGACCTTTAT AAACTCATTT TGAAAAAAAA GGATGAATTG 
GGGGATAGAT CTATAATGTT CACTGTTCAA AACGAAGACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_014971148.1
CDS	1362..1943
Translation	MAAEPAEDNCINFVAMKFIDSTLYFIAEDDENLESDYFGKLESKLSIIRNLNDQVLFIDQGNRPLFEDMTDSDCRDNAPRTIFIINMYKDSQPRGMAVAISVKCEKISTLSCENRIISFKEMNPPDNIKDTKSDIIFFQRSVPGHDNKMQFESSSYEGYFLACEKERDLYKLILKKKDELGDRSIMFTVQNED

Target ORF information:

RefSeq Version	XM_015115662.1
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta interleukin 18 (IL18), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015115662.1

ORF Insert Sequence:

ATGGCTGCTG AACCAGCAGA AGACAATTGC ATCAATTTTG TGGCAATGAA ATTTATTGAC 
AGTACGCTTT ACTTTATAGC TGAAGATGAT GAAAACCTGG AATCAGATTA CTTTGGCAAG 
CTTGAATCTA AATTATCAAT CATAAGAAAT TTGAATGACC AAGTTCTCTT CATTGACCAA 
GGAAATCGGC CCCTATTTGA AGATATGACT GATTCTGACT GTAGAGATAA TGCACCCCGG 
ACCATATTTA TTATAAATAT GTATAAAGAT AGCCAGCCTA GAGGTATGGC TGTAGCCATC 
TCTGTGAAAT GTGAGAAAAT TTCAACTCTC TCCTGTGAGA ACAGAATTAT TTCCTTTAAG 
GAAATGAATC CTCCTGATAA CATCAAGGAT ACGAAAAGTG ACATCATATT CTTTCAGAGA 
AGTGTCCCAG GACATGATAA TAAGATGCAA TTTGAATCTT CATCATACGA AGGATACTTT 
CTAGCTTGTG AAAAAGAGAG AGACCTTTAT AAACTCATTT TGAAAAAAAA GGATGAATTG 
GGGGATAGAT CTATAATGTT CACTGTTCAA AACGAAGACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IL18 ( XM_015115661.2 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> XP_014971147.1 Macaca mulatta interleukin 18 (IL18), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMb00169
Clone ID Related Accession (Same CDS sequence)	XM_015115662.1 , NM_001032834.2 , XM_015115661.2 , XM_015115661.1 , XM_015115662.2
Accession Version	XM_015115661.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-25
Organism	Macaca mulatta(Rhesus monkey)
Product	interleukin-18 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041767.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 23, 2019 this sequence version replaced XM_015115661.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGCTG AACCAGCAGA AGACAATTGC ATCAATTTTG TGGCAATGAA ATTTATTGAC 
AGTACGCTTT ACTTTATAGC TGAAGATGAT GAAAACCTGG AATCAGATTA CTTTGGCAAG 
CTTGAATCTA AATTATCAAT CATAAGAAAT TTGAATGACC AAGTTCTCTT CATTGACCAA 
GGAAATCGGC CCCTATTTGA AGATATGACT GATTCTGACT GTAGAGATAA TGCACCCCGG 
ACCATATTTA TTATAAATAT GTATAAAGAT AGCCAGCCTA GAGGTATGGC TGTAGCCATC 
TCTGTGAAAT GTGAGAAAAT TTCAACTCTC TCCTGTGAGA ACAGAATTAT TTCCTTTAAG 
GAAATGAATC CTCCTGATAA CATCAAGGAT ACGAAAAGTG ACATCATATT CTTTCAGAGA 
AGTGTCCCAG GACATGATAA TAAGATGCAA TTTGAATCTT CATCATACGA AGGATACTTT 
CTAGCTTGTG AAAAAGAGAG AGACCTTTAT AAACTCATTT TGAAAAAAAA GGATGAATTG 
GGGGATAGAT CTATAATGTT CACTGTTCAA AACGAAGACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_014971147.1
CDS	947..1528
Translation	MAAEPAEDNCINFVAMKFIDSTLYFIAEDDENLESDYFGKLESKLSIIRNLNDQVLFIDQGNRPLFEDMTDSDCRDNAPRTIFIINMYKDSQPRGMAVAISVKCEKISTLSCENRIISFKEMNPPDNIKDTKSDIIFFQRSVPGHDNKMQFESSSYEGYFLACEKERDLYKLILKKKDELGDRSIMFTVQNED

Target ORF information:

RefSeq Version	XM_015115661.2
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta interleukin 18 (IL18), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015115661.2

ORF Insert Sequence:

ATGGCTGCTG AACCAGCAGA AGACAATTGC ATCAATTTTG TGGCAATGAA ATTTATTGAC 
AGTACGCTTT ACTTTATAGC TGAAGATGAT GAAAACCTGG AATCAGATTA CTTTGGCAAG 
CTTGAATCTA AATTATCAAT CATAAGAAAT TTGAATGACC AAGTTCTCTT CATTGACCAA 
GGAAATCGGC CCCTATTTGA AGATATGACT GATTCTGACT GTAGAGATAA TGCACCCCGG 
ACCATATTTA TTATAAATAT GTATAAAGAT AGCCAGCCTA GAGGTATGGC TGTAGCCATC 
TCTGTGAAAT GTGAGAAAAT TTCAACTCTC TCCTGTGAGA ACAGAATTAT TTCCTTTAAG 
GAAATGAATC CTCCTGATAA CATCAAGGAT ACGAAAAGTG ACATCATATT CTTTCAGAGA 
AGTGTCCCAG GACATGATAA TAAGATGCAA TTTGAATCTT CATCATACGA AGGATACTTT 
CTAGCTTGTG AAAAAGAGAG AGACCTTTAT AAACTCATTT TGAAAAAAAA GGATGAATTG 
GGGGATAGAT CTATAATGTT CACTGTTCAA AACGAAGACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IL18 ( XM_015115661.1 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> XP_014971147.1 Macaca mulatta interleukin 18 (IL18), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMb00169
Clone ID Related Accession (Same CDS sequence)	XM_015115662.1 , NM_001032834.2 , XM_015115661.2 , XM_015115661.1 , XM_015115662.2
Accession Version	XM_015115661.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-12-20
Organism	Macaca mulatta(Rhesus monkey)
Product	interleukin-18 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014805472.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Macaca mulatta Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGCTG AACCAGCAGA AGACAATTGC ATCAATTTTG TGGCAATGAA ATTTATTGAC 
AGTACGCTTT ACTTTATAGC TGAAGATGAT GAAAACCTGG AATCAGATTA CTTTGGCAAG 
CTTGAATCTA AATTATCAAT CATAAGAAAT TTGAATGACC AAGTTCTCTT CATTGACCAA 
GGAAATCGGC CCCTATTTGA AGATATGACT GATTCTGACT GTAGAGATAA TGCACCCCGG 
ACCATATTTA TTATAAATAT GTATAAAGAT AGCCAGCCTA GAGGTATGGC TGTAGCCATC 
TCTGTGAAAT GTGAGAAAAT TTCAACTCTC TCCTGTGAGA ACAGAATTAT TTCCTTTAAG 
GAAATGAATC CTCCTGATAA CATCAAGGAT ACGAAAAGTG ACATCATATT CTTTCAGAGA 
AGTGTCCCAG GACATGATAA TAAGATGCAA TTTGAATCTT CATCATACGA AGGATACTTT 
CTAGCTTGTG AAAAAGAGAG AGACCTTTAT AAACTCATTT TGAAAAAAAA GGATGAATTG 
GGGGATAGAT CTATAATGTT CACTGTTCAA AACGAAGACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_014971147.1
CDS	1266..1847
Translation	MAAEPAEDNCINFVAMKFIDSTLYFIAEDDENLESDYFGKLESKLSIIRNLNDQVLFIDQGNRPLFEDMTDSDCRDNAPRTIFIINMYKDSQPRGMAVAISVKCEKISTLSCENRIISFKEMNPPDNIKDTKSDIIFFQRSVPGHDNKMQFESSSYEGYFLACEKERDLYKLILKKKDELGDRSIMFTVQNED

Target ORF information:

RefSeq Version	XM_015115661.1
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta interleukin 18 (IL18), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015115661.1

ORF Insert Sequence:

ATGGCTGCTG AACCAGCAGA AGACAATTGC ATCAATTTTG TGGCAATGAA ATTTATTGAC 
AGTACGCTTT ACTTTATAGC TGAAGATGAT GAAAACCTGG AATCAGATTA CTTTGGCAAG 
CTTGAATCTA AATTATCAAT CATAAGAAAT TTGAATGACC AAGTTCTCTT CATTGACCAA 
GGAAATCGGC CCCTATTTGA AGATATGACT GATTCTGACT GTAGAGATAA TGCACCCCGG 
ACCATATTTA TTATAAATAT GTATAAAGAT AGCCAGCCTA GAGGTATGGC TGTAGCCATC 
TCTGTGAAAT GTGAGAAAAT TTCAACTCTC TCCTGTGAGA ACAGAATTAT TTCCTTTAAG 
GAAATGAATC CTCCTGATAA CATCAAGGAT ACGAAAAGTG ACATCATATT CTTTCAGAGA 
AGTGTCCCAG GACATGATAA TAAGATGCAA TTTGAATCTT CATCATACGA AGGATACTTT 
CTAGCTTGTG AAAAAGAGAG AGACCTTTAT AAACTCATTT TGAAAAAAAA GGATGAATTG 
GGGGATAGAT CTATAATGTT CACTGTTCAA AACGAAGACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IL18 ( XM_015115662.2 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> XP_014971148.1 Macaca mulatta interleukin 18 (IL18), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMb00169
Clone ID Related Accession (Same CDS sequence)	XM_015115662.1 , NM_001032834.2 , XM_015115661.2 , XM_015115661.1 , XM_015115662.2
Accession Version	XM_015115662.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-25
Organism	Macaca mulatta(Rhesus monkey)
Product	interleukin-18 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041767.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 23, 2019 this sequence version replaced XM_015115662.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGCTG AACCAGCAGA AGACAATTGC ATCAATTTTG TGGCAATGAA ATTTATTGAC 
AGTACGCTTT ACTTTATAGC TGAAGATGAT GAAAACCTGG AATCAGATTA CTTTGGCAAG 
CTTGAATCTA AATTATCAAT CATAAGAAAT TTGAATGACC AAGTTCTCTT CATTGACCAA 
GGAAATCGGC CCCTATTTGA AGATATGACT GATTCTGACT GTAGAGATAA TGCACCCCGG 
ACCATATTTA TTATAAATAT GTATAAAGAT AGCCAGCCTA GAGGTATGGC TGTAGCCATC 
TCTGTGAAAT GTGAGAAAAT TTCAACTCTC TCCTGTGAGA ACAGAATTAT TTCCTTTAAG 
GAAATGAATC CTCCTGATAA CATCAAGGAT ACGAAAAGTG ACATCATATT CTTTCAGAGA 
AGTGTCCCAG GACATGATAA TAAGATGCAA TTTGAATCTT CATCATACGA AGGATACTTT 
CTAGCTTGTG AAAAAGAGAG AGACCTTTAT AAACTCATTT TGAAAAAAAA GGATGAATTG 
GGGGATAGAT CTATAATGTT CACTGTTCAA AACGAAGACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_014971148.1
CDS	1036..1617
Translation	MAAEPAEDNCINFVAMKFIDSTLYFIAEDDENLESDYFGKLESKLSIIRNLNDQVLFIDQGNRPLFEDMTDSDCRDNAPRTIFIINMYKDSQPRGMAVAISVKCEKISTLSCENRIISFKEMNPPDNIKDTKSDIIFFQRSVPGHDNKMQFESSSYEGYFLACEKERDLYKLILKKKDELGDRSIMFTVQNED

Target ORF information:

RefSeq Version	XM_015115662.2
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta interleukin 18 (IL18), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015115662.2

ORF Insert Sequence:

ATGGCTGCTG AACCAGCAGA AGACAATTGC ATCAATTTTG TGGCAATGAA ATTTATTGAC 
AGTACGCTTT ACTTTATAGC TGAAGATGAT GAAAACCTGG AATCAGATTA CTTTGGCAAG 
CTTGAATCTA AATTATCAAT CATAAGAAAT TTGAATGACC AAGTTCTCTT CATTGACCAA 
GGAAATCGGC CCCTATTTGA AGATATGACT GATTCTGACT GTAGAGATAA TGCACCCCGG 
ACCATATTTA TTATAAATAT GTATAAAGAT AGCCAGCCTA GAGGTATGGC TGTAGCCATC 
TCTGTGAAAT GTGAGAAAAT TTCAACTCTC TCCTGTGAGA ACAGAATTAT TTCCTTTAAG 
GAAATGAATC CTCCTGATAA CATCAAGGAT ACGAAAAGTG ACATCATATT CTTTCAGAGA 
AGTGTCCCAG GACATGATAA TAAGATGCAA TTTGAATCTT CATCATACGA AGGATACTTT 
CTAGCTTGTG AAAAAGAGAG AGACCTTTAT AAACTCATTT TGAAAAAAAA GGATGAATTG 
GGGGATAGAT CTATAATGTT CACTGTTCAA AACGAAGACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IL18 ( XM_015115663.1 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> XP_014971149.1 Macaca mulatta interleukin 18 (IL18), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMb47808
Clone ID Related Accession (Same CDS sequence)	XM_015115663.1 , XM_015115663.2
Accession Version	XM_015115663.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-12-20
Organism	Macaca mulatta(Rhesus monkey)
Product	interleukin-18 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014805472.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Macaca mulatta Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGCTG AACCAGCAGA AGACAATTGC ATCAATTTTG TGGCAATGAA ATTTATTGAC 
AGTACGCTTT ACTTTATAGA AAACCTGGAA TCAGATTACT TTGGCAAGCT TGAATCTAAA 
TTATCAATCA TAAGAAATTT GAATGACCAA GTTCTCTTCA TTGACCAAGG AAATCGGCCC 
CTATTTGAAG ATATGACTGA TTCTGACTGT AGAGATAATG CACCCCGGAC CATATTTATT 
ATAAATATGT ATAAAGATAG CCAGCCTAGA GGTATGGCTG TAGCCATCTC TGTGAAATGT 
GAGAAAATTT CAACTCTCTC CTGTGAGAAC AGAATTATTT CCTTTAAGGA AATGAATCCT 
CCTGATAACA TCAAGGATAC GAAAAGTGAC ATCATATTCT TTCAGAGAAG TGTCCCAGGA 
CATGATAATA AGATGCAATT TGAATCTTCA TCATACGAAG GATACTTTCT AGCTTGTGAA 
AAAGAGAGAG ACCTTTATAA ACTCATTTTG AAAAAAAAGG ATGAATTGGG GGATAGATCT 
ATAATGTTCA CTGTTCAAAA CGAAGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_014971149.1
CDS	1934..2503
Translation	MAAEPAEDNCINFVAMKFIDSTLYFIENLESDYFGKLESKLSIIRNLNDQVLFIDQGNRPLFEDMTDSDCRDNAPRTIFIINMYKDSQPRGMAVAISVKCEKISTLSCENRIISFKEMNPPDNIKDTKSDIIFFQRSVPGHDNKMQFESSSYEGYFLACEKERDLYKLILKKKDELGDRSIMFTVQNED

Target ORF information:

RefSeq Version	XM_015115663.1
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta interleukin 18 (IL18), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015115663.1

ORF Insert Sequence:

ATGGCTGCTG AACCAGCAGA AGACAATTGC ATCAATTTTG TGGCAATGAA ATTTATTGAC 
AGTACGCTTT ACTTTATAGA AAACCTGGAA TCAGATTACT TTGGCAAGCT TGAATCTAAA 
TTATCAATCA TAAGAAATTT GAATGACCAA GTTCTCTTCA TTGACCAAGG AAATCGGCCC 
CTATTTGAAG ATATGACTGA TTCTGACTGT AGAGATAATG CACCCCGGAC CATATTTATT 
ATAAATATGT ATAAAGATAG CCAGCCTAGA GGTATGGCTG TAGCCATCTC TGTGAAATGT 
GAGAAAATTT CAACTCTCTC CTGTGAGAAC AGAATTATTT CCTTTAAGGA AATGAATCCT 
CCTGATAACA TCAAGGATAC GAAAAGTGAC ATCATATTCT TTCAGAGAAG TGTCCCAGGA 
CATGATAATA AGATGCAATT TGAATCTTCA TCATACGAAG GATACTTTCT AGCTTGTGAA 
AAAGAGAGAG ACCTTTATAA ACTCATTTTG AAAAAAAAGG ATGAATTGGG GGATAGATCT 
ATAATGTTCA CTGTTCAAAA CGAAGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IL18 ( XM_015115663.2 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> XP_014971149.1 Macaca mulatta interleukin 18 (IL18), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMb47808
Clone ID Related Accession (Same CDS sequence)	XM_015115663.1 , XM_015115663.2
Accession Version	XM_015115663.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-25
Organism	Macaca mulatta(Rhesus monkey)
Product	interleukin-18 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_041767.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 23, 2019 this sequence version replaced XM_015115663.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Macaca mulatta Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGCTG AACCAGCAGA AGACAATTGC ATCAATTTTG TGGCAATGAA ATTTATTGAC 
AGTACGCTTT ACTTTATAGA AAACCTGGAA TCAGATTACT TTGGCAAGCT TGAATCTAAA 
TTATCAATCA TAAGAAATTT GAATGACCAA GTTCTCTTCA TTGACCAAGG AAATCGGCCC 
CTATTTGAAG ATATGACTGA TTCTGACTGT AGAGATAATG CACCCCGGAC CATATTTATT 
ATAAATATGT ATAAAGATAG CCAGCCTAGA GGTATGGCTG TAGCCATCTC TGTGAAATGT 
GAGAAAATTT CAACTCTCTC CTGTGAGAAC AGAATTATTT CCTTTAAGGA AATGAATCCT 
CCTGATAACA TCAAGGATAC GAAAAGTGAC ATCATATTCT TTCAGAGAAG TGTCCCAGGA 
CATGATAATA AGATGCAATT TGAATCTTCA TCATACGAAG GATACTTTCT AGCTTGTGAA 
AAAGAGAGAG ACCTTTATAA ACTCATTTTG AAAAAAAAGG ATGAATTGGG GGATAGATCT 
ATAATGTTCA CTGTTCAAAA CGAAGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_014971149.1
CDS	947..1516
Translation	MAAEPAEDNCINFVAMKFIDSTLYFIENLESDYFGKLESKLSIIRNLNDQVLFIDQGNRPLFEDMTDSDCRDNAPRTIFIINMYKDSQPRGMAVAISVKCEKISTLSCENRIISFKEMNPPDNIKDTKSDIIFFQRSVPGHDNKMQFESSSYEGYFLACEKERDLYKLILKKKDELGDRSIMFTVQNED

Target ORF information:

RefSeq Version	XM_015115663.2
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta interleukin 18 (IL18), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015115663.2

ORF Insert Sequence:

ATGGCTGCTG AACCAGCAGA AGACAATTGC ATCAATTTTG TGGCAATGAA ATTTATTGAC 
AGTACGCTTT ACTTTATAGA AAACCTGGAA TCAGATTACT TTGGCAAGCT TGAATCTAAA 
TTATCAATCA TAAGAAATTT GAATGACCAA GTTCTCTTCA TTGACCAAGG AAATCGGCCC 
CTATTTGAAG ATATGACTGA TTCTGACTGT AGAGATAATG CACCCCGGAC CATATTTATT 
ATAAATATGT ATAAAGATAG CCAGCCTAGA GGTATGGCTG TAGCCATCTC TGTGAAATGT 
GAGAAAATTT CAACTCTCTC CTGTGAGAAC AGAATTATTT CCTTTAAGGA AATGAATCCT 
CCTGATAACA TCAAGGATAC GAAAAGTGAC ATCATATTCT TTCAGAGAAG TGTCCCAGGA 
CATGATAATA AGATGCAATT TGAATCTTCA TCATACGAAG GATACTTTCT AGCTTGTGAA 
AAAGAGAGAG ACCTTTATAA ACTCATTTTG AAAAAAAAGG ATGAATTGGG GGATAGATCT 
ATAATGTTCA CTGTTCAAAA CGAAGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Urine Interleukin-18 (IL-18) as a Biomarker of Total-Body Irradiation: A Preliminary Study in Nonhuman Primates.
Radiation research188(3)325-334(2017 09)
Xiao M,Bolduc DL,Li X,Cui W,Hieber KP,B?nger R,Ossetrova NI

A new rhesus macaque assembly and annotation for next-generation sequencing analyses.
Biology direct9(1)20(2014 Oct)
Zimin AV,Cornish AS,Maudhoo MD,Gibbs RM,Zhang X,Pandey S,Meehan DT,Wipfler K,Bosinger SE,Johnson ZP,Tharp GK,Mar?ais G,Roberts M,Ferguson B,Fox HS,Treangen T,Salzberg SL,Yorke JA,Norgren RB Jr

AIDS progression is associated with the emergence of IL-17-producing cells early after simian immunodeficiency virus infection.
Journal of immunology (Baltimore, Md. : 1950)184(2)984-92(2010 Jan)
Campillo-Gimenez L,Cumont MC,Fay M,Kared H,Monceaux V,Diop O,M?ller-Trutwin M,Hurtrel B,L?vy Y,Zaunders J,Dy M,Leite-de-Moraes MC,Elbim C,Estaquier J

Interleukin-18 predicts atherosclerosis progression in SIV-infected and uninfected rhesus monkeys (Macaca mulatta) on a high-fat/high-cholesterol diet.
Laboratory investigation; a journal of technical methods and pathology89(6)657-67(2009 Jun)
Yearley JH,Xia D,Pearson CB,Carville A,Shannon RP,Mansfield KG

Expression of the interleukin-18 gene from rhesus macaque by the simian immunodeficiency virus does not result in increased viral replication.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research21(3)173-80(2001 Mar)
Giavedoni LD,Imhoof JD,Velasquillo MC,Parodi LM,Hodara VL

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IL18 cDNA ORF clone, Macaca mulatta(Rhesus monkey)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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