SCARB2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SCARB2
Entrez Gene ID	950
Full Name	scavenger receptor class B member 2
Synonyms	AMRF,CD36L2,EPM4,HLGP85,LGP85,LIMP-2,LIMPII,SR-BII
General protein information	Preferred Names scavenger receptor class B member 2 Names lysosome membrane protein 2 85 kDa lysosomal membrane sialoglycoprotein 85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2 CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II) CD36 antigen-like 2 LIMP II lysosome membrane protein II
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4q21.1
Summary	The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011].
Disorder MIM:	602257
Disorder Html:	Epilepsy, progressive myoclonic 4, with or without renal failure, 254900 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_005506.3	NP_005497.1	lysosome membrane protein 2 isoform 1 precursor
NM_001204255.2	NP_001191184.1	lysosome membrane protein 2 isoform 2 precursor
NM_001204255.1	NP_001191184.1	lysosome membrane protein 2 isoform 2 precursor
NM_005506.4	NP_005497.1	lysosome membrane protein 2 isoform 1 precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	SCARB2	NP_001095623.1
Drosophila melanogaster (fruit fly)	emp	NP_726504.2
Canis lupus familiaris (dog)	SCARB2	XP_005639134.1
Gallus gallus (chicken)	SCARB2	XP_420593.1
Danio rerio (zebrafish)	LOC100536792	XP_003198729.1
Anopheles gambiae (African malaria mosquito)	SCRB9	XP_314345.2
Pan troglodytes (chimpanzee)	SCARB2	XP_517214.2
Rattus norvegicus (Norway rat)	Scarb2	NP_446453.1
Danio rerio (zebrafish)	scarb2	NP_775366.1
Danio rerio (zebrafish)	LOC564077	XP_003200850.2
Xenopus tropicalis (tropical clawed frog)	scarb2	NP_001016557.1
Mus musculus (house mouse)	Scarb2	NP_031670.1
Homo sapiens (human)	SCARB2	NP_005497.1
	SCARB2	XP_001096458.1

Gene Ontology

The following SCARB2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SCARB2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu21396	NM_005506.4 Latest version!	Homo sapiens scavenger receptor class B member 2 (SCARB2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu10715	NM_001204255.2 Latest version!	Homo sapiens scavenger receptor class B member 2 (SCARB2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu10715	NM_001204255.1	Homo sapiens scavenger receptor class B member 2 (SCARB2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu21396	NM_005506.3	Homo sapiens scavenger receptor class B member 2 (SCARB2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SCARB2 ( NM_005506.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005497.1 Homo sapiens scavenger receptor class B member 2 (SCARB2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21396
Clone ID Related Accession (Same CDS sequence)	NM_005506.3 , NM_005506.4
Accession Version	NM_005506.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1437bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-27
Organism	Homo sapiens(human)
Product	lysosome membrane protein 2 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC034139.7, AK313016.1, AC110795.4 and BC035111.1. This sequence is a reference standard in the RefSeqGene project. On Feb 23, 2011 this sequence version replaced NM_005506.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.184004.1, SRR1803615.202913.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467146 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGCCGAT GCTGCTTCTA CACGGCGGGG ACGTTGTCCC TGCTCCTGCT GGTGACCAGC 
GTCACGCTGC TGGTGGCCCG GGTCTTCCAG AAGGCTGTAG ACCAGAGTAT CGAGAAGAAA 
ATTGTGTTAA GGAATGGTAC TGAGGCATTT GACTCCTGGG AGAAGCCCCC TCTGCCTGTG 
TATACTCAGT TCTATTTCTT CAATGTCACC AATCCAGAGG AGATCCTCAG AGGGGAGACC 
CCTCGGGTGG AAGAAGTGGG GCCATACACC TACAGGGAAC TCAGAAACAA AGCAAATATT 
CAATTTGGAG ATAATGGAAC AACAATATCT GCTGTTAGCA ACAAGGCCTA TGTTTTTGAA 
CGAGACCAAT CTGTTGGAGA CCCTAAAATT GACTTAATTA GAACATTAAA TATTCCTGTA 
TTGACTGTCA TAGAGTGGTC CCAGGTGCAC TTCCTCAGGG AGATCATCGA GGCCATGTTG 
AAAGCCTATC AGCAGAAGCT CTTTGTGACT CACACAGTTG ACGAATTGCT CTGGGGCTAC 
AAAGATGAAA TCTTGTCCCT TATCCATGTT TTCAGGCCCG ATATCTCTCC CTATTTTGGC 
CTATTCTATG AGAAAAATGG GACTAATGAT GGAGACTATG TTTTTCTAAC TGGAGAAGAC 
AGTTACCTTA ACTTTACAAA AATTGTGGAA TGGAATGGGA AAACGTCACT TGACTGGTGG 
ATAACAGACA AGTGCAATAT GATTAATGGA ACAGATGGAG ATTCTTTTCA CCCACTAATA 
ACCAAAGATG AGGTCCTTTA TGTCTTCCCA TCTGACTTTT GCAGGTCAGT GTATATTACT 
TTCAGTGACT ATGAGAGTGT ACAGGGACTG CCTGCCTTTC GGTATAAAGT TCCTGCAGAA 
ATATTAGCCA ATACGTCAGA CAATGCCGGC TTCTGTATAC CTGAGGGAAA CTGCCTGGGC 
TCAGGAGTTC TGAATGTCAG CATCTGCAAG AATGGTGCAC CCATCATTAT GTCTTTCCCA 
CACTTTTACC AAGCAGATGA GAGGTTTGTT TCTGCCATAG AAGGCATGCA CCCAAATCAG 
GAAGACCATG AGACATTTGT GGACATTAAT CCTTTGACTG GAATAATCCT AAAAGCAGCC 
AAGAGGTTCC AAATCAACAT TTATGTCAAA AAATTAGATG ACTTTGTTGA AACGGGAGAC 
ATTAGAACCA TGGTTTTCCC AGTGATGTAC CTCAATGAGA GTGTTCACAT TGATAAAGAG 
ACGGCGAGTC GACTGAAGTC TATGATTAAC ACTACTTTGA TCATCACCAA CATACCCTAC 
ATCATCATGG CGCTGGGTGT GTTCTTTGGT TTGGTTTTTA CCTGGCTTGC ATGCAAAGGA 
CAGGGATCCA TGGATGAGGG AACAGCGGAT GAAAGAGCAC CCCTCATTCG AACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005497.1
CDS	357..1793
Translation	MGRCCFYTAGTLSLLLLVTSVTLLVARVFQKAVDQSIEKKIVLRNGTEAFDSWEKPPLPVYTQFYFFNVTNPEEILRGETPRVEEVGPYTYRELRNKANIQFGDNGTTISAVSNKAYVFERDQSVGDPKIDLIRTLNIPVLTVIEWSQVHFLREIIEAMLKAYQQKLFVTHTVDELLWGYKDEILSLIHVFRPDISPYFGLFYEKNGTNDGDYVFLTGEDSYLNFTKIVEWNGKTSLDWWITDKCNMINGTDGDSFHPLITKDEVLYVFPSDFCRSVYITFSDYESVQGLPAFRYKVPAEILANTSDNAGFCIPEGNCLGSGVLNVSICKNGAPIIMSFPHFYQADERFVSAIEGMHPNQEDHETFVDINPLTGIILKAAKRFQINIYVKKLDDFVETGDIRTMVFPVMYLNESVHIDKETASRLKSMINTTLIITNIPYIIMALGVFFGLVFTWLACKGQGSMDEGTADERAPLIRT

Target ORF information:

RefSeq Version	NM_005506.3
Organism	Homo sapiens(human)
Definition	Homo sapiens scavenger receptor class B member 2 (SCARB2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005506.3

ORF Insert Sequence:

ATGGGCCGAT GCTGCTTCTA CACGGCGGGG ACGTTGTCCC TGCTCCTGCT GGTGACCAGC 
GTCACGCTGC TGGTGGCCCG GGTCTTCCAG AAGGCTGTAG ACCAGAGTAT CGAGAAGAAA 
ATTGTGTTAA GGAATGGTAC TGAGGCATTT GACTCCTGGG AGAAGCCCCC TCTGCCTGTG 
TATACTCAGT TCTATTTCTT CAATGTCACC AATCCAGAGG AGATCCTCAG AGGGGAGACC 
CCTCGGGTGG AAGAAGTGGG GCCATACACC TACAGGGAAC TCAGAAACAA AGCAAATATT 
CAATTTGGAG ATAATGGAAC AACAATATCT GCTGTTAGCA ACAAGGCCTA TGTTTTTGAA 
CGAGACCAAT CTGTTGGAGA CCCTAAAATT GACTTAATTA GAACATTAAA TATTCCTGTA 
TTGACTGTCA TAGAGTGGTC CCAGGTGCAC TTCCTCAGGG AGATCATCGA GGCCATGTTG 
AAAGCCTATC AGCAGAAGCT CTTTGTGACT CACACAGTTG ACGAATTGCT CTGGGGCTAC 
AAAGATGAAA TCTTGTCCCT TATCCATGTT TTCAGGCCCG ATATCTCTCC CTATTTTGGC 
CTATTCTATG AGAAAAATGG GACTAATGAT GGAGACTATG TTTTTCTAAC TGGAGAAGAC 
AGTTACCTTA ACTTTACAAA AATTGTGGAA TGGAATGGGA AAACGTCACT TGACTGGTGG 
ATAACAGACA AGTGCAATAT GATTAATGGA ACAGATGGAG ATTCTTTTCA CCCACTAATA 
ACCAAAGATG AGGTCCTTTA TGTCTTCCCA TCTGACTTTT GCAGGTCAGT GTATATTACT 
TTCAGTGACT ATGAGAGTGT ACAGGGACTG CCTGCCTTTC GGTATAAAGT TCCTGCAGAA 
ATATTAGCCA ATACGTCAGA CAATGCCGGC TTCTGTATAC CTGAGGGAAA CTGCCTGGGC 
TCAGGAGTTC TGAATGTCAG CATCTGCAAG AATGGTGCAC CCATCATTAT GTCTTTCCCA 
CACTTTTACC AAGCAGATGA GAGGTTTGTT TCTGCCATAG AAGGCATGCA CCCAAATCAG 
GAAGACCATG AGACATTTGT GGACATTAAT CCTTTGACTG GAATAATCCT AAAAGCAGCC 
AAGAGGTTCC AAATCAACAT TTATGTCAAA AAATTAGATG ACTTTGTTGA AACGGGAGAC 
ATTAGAACCA TGGTTTTCCC AGTGATGTAC CTCAATGAGA GTGTTCACAT TGATAAAGAG 
ACGGCGAGTC GACTGAAGTC TATGATTAAC ACTACTTTGA TCATCACCAA CATACCCTAC 
ATCATCATGG CGCTGGGTGT GTTCTTTGGT TTGGTTTTTA CCTGGCTTGC ATGCAAAGGA 
CAGGGATCCA TGGATGAGGG AACAGCGGAT GAAAGAGCAC CCCTCATTCG AACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SCARB2 ( NM_005506.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005497.1 Homo sapiens scavenger receptor class B member 2 (SCARB2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21396
Clone ID Related Accession (Same CDS sequence)	NM_005506.3 , NM_005506.4
Accession Version	NM_005506.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1437bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Homo sapiens(human)
Product	lysosome membrane protein 2 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC034139.7, AK313016.1, AC110795.4 and BC035111.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_005506.3. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.98024.1, SRR1660809.148205.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467146 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000264896.8/ ENSP00000264896.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGCCGAT GCTGCTTCTA CACGGCGGGG ACGTTGTCCC TGCTCCTGCT GGTGACCAGC 
GTCACGCTGC TGGTGGCCCG GGTCTTCCAG AAGGCTGTAG ACCAGAGTAT CGAGAAGAAA 
ATTGTGTTAA GGAATGGTAC TGAGGCATTT GACTCCTGGG AGAAGCCCCC TCTGCCTGTG 
TATACTCAGT TCTATTTCTT CAATGTCACC AATCCAGAGG AGATCCTCAG AGGGGAGACC 
CCTCGGGTGG AAGAAGTGGG GCCATACACC TACAGGGAAC TCAGAAACAA AGCAAATATT 
CAATTTGGAG ATAATGGAAC AACAATATCT GCTGTTAGCA ACAAGGCCTA TGTTTTTGAA 
CGAGACCAAT CTGTTGGAGA CCCTAAAATT GACTTAATTA GAACATTAAA TATTCCTGTA 
TTGACTGTCA TAGAGTGGTC CCAGGTGCAC TTCCTCAGGG AGATCATCGA GGCCATGTTG 
AAAGCCTATC AGCAGAAGCT CTTTGTGACT CACACAGTTG ACGAATTGCT CTGGGGCTAC 
AAAGATGAAA TCTTGTCCCT TATCCATGTT TTCAGGCCCG ATATCTCTCC CTATTTTGGC 
CTATTCTATG AGAAAAATGG GACTAATGAT GGAGACTATG TTTTTCTAAC TGGAGAAGAC 
AGTTACCTTA ACTTTACAAA AATTGTGGAA TGGAATGGGA AAACGTCACT TGACTGGTGG 
ATAACAGACA AGTGCAATAT GATTAATGGA ACAGATGGAG ATTCTTTTCA CCCACTAATA 
ACCAAAGATG AGGTCCTTTA TGTCTTCCCA TCTGACTTTT GCAGGTCAGT GTATATTACT 
TTCAGTGACT ATGAGAGTGT ACAGGGACTG CCTGCCTTTC GGTATAAAGT TCCTGCAGAA 
ATATTAGCCA ATACGTCAGA CAATGCCGGC TTCTGTATAC CTGAGGGAAA CTGCCTGGGC 
TCAGGAGTTC TGAATGTCAG CATCTGCAAG AATGGTGCAC CCATCATTAT GTCTTTCCCA 
CACTTTTACC AAGCAGATGA GAGGTTTGTT TCTGCCATAG AAGGCATGCA CCCAAATCAG 
GAAGACCATG AGACATTTGT GGACATTAAT CCTTTGACTG GAATAATCCT AAAAGCAGCC 
AAGAGGTTCC AAATCAACAT TTATGTCAAA AAATTAGATG ACTTTGTTGA AACGGGAGAC 
ATTAGAACCA TGGTTTTCCC AGTGATGTAC CTCAATGAGA GTGTTCACAT TGATAAAGAG 
ACGGCGAGTC GACTGAAGTC TATGATTAAC ACTACTTTGA TCATCACCAA CATACCCTAC 
ATCATCATGG CGCTGGGTGT GTTCTTTGGT TTGGTTTTTA CCTGGCTTGC ATGCAAAGGA 
CAGGGATCCA TGGATGAGGG AACAGCGGAT GAAAGAGCAC CCCTCATTCG AACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005497.1
CDS	282..1718
Translation	MGRCCFYTAGTLSLLLLVTSVTLLVARVFQKAVDQSIEKKIVLRNGTEAFDSWEKPPLPVYTQFYFFNVTNPEEILRGETPRVEEVGPYTYRELRNKANIQFGDNGTTISAVSNKAYVFERDQSVGDPKIDLIRTLNIPVLTVIEWSQVHFLREIIEAMLKAYQQKLFVTHTVDELLWGYKDEILSLIHVFRPDISPYFGLFYEKNGTNDGDYVFLTGEDSYLNFTKIVEWNGKTSLDWWITDKCNMINGTDGDSFHPLITKDEVLYVFPSDFCRSVYITFSDYESVQGLPAFRYKVPAEILANTSDNAGFCIPEGNCLGSGVLNVSICKNGAPIIMSFPHFYQADERFVSAIEGMHPNQEDHETFVDINPLTGIILKAAKRFQINIYVKKLDDFVETGDIRTMVFPVMYLNESVHIDKETASRLKSMINTTLIITNIPYIIMALGVFFGLVFTWLACKGQGSMDEGTADERAPLIRT

Target ORF information:

RefSeq Version	NM_005506.4
Organism	Homo sapiens(human)
Definition	Homo sapiens scavenger receptor class B member 2 (SCARB2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005506.4

ORF Insert Sequence:

ATGGGCCGAT GCTGCTTCTA CACGGCGGGG ACGTTGTCCC TGCTCCTGCT GGTGACCAGC 
GTCACGCTGC TGGTGGCCCG GGTCTTCCAG AAGGCTGTAG ACCAGAGTAT CGAGAAGAAA 
ATTGTGTTAA GGAATGGTAC TGAGGCATTT GACTCCTGGG AGAAGCCCCC TCTGCCTGTG 
TATACTCAGT TCTATTTCTT CAATGTCACC AATCCAGAGG AGATCCTCAG AGGGGAGACC 
CCTCGGGTGG AAGAAGTGGG GCCATACACC TACAGGGAAC TCAGAAACAA AGCAAATATT 
CAATTTGGAG ATAATGGAAC AACAATATCT GCTGTTAGCA ACAAGGCCTA TGTTTTTGAA 
CGAGACCAAT CTGTTGGAGA CCCTAAAATT GACTTAATTA GAACATTAAA TATTCCTGTA 
TTGACTGTCA TAGAGTGGTC CCAGGTGCAC TTCCTCAGGG AGATCATCGA GGCCATGTTG 
AAAGCCTATC AGCAGAAGCT CTTTGTGACT CACACAGTTG ACGAATTGCT CTGGGGCTAC 
AAAGATGAAA TCTTGTCCCT TATCCATGTT TTCAGGCCCG ATATCTCTCC CTATTTTGGC 
CTATTCTATG AGAAAAATGG GACTAATGAT GGAGACTATG TTTTTCTAAC TGGAGAAGAC 
AGTTACCTTA ACTTTACAAA AATTGTGGAA TGGAATGGGA AAACGTCACT TGACTGGTGG 
ATAACAGACA AGTGCAATAT GATTAATGGA ACAGATGGAG ATTCTTTTCA CCCACTAATA 
ACCAAAGATG AGGTCCTTTA TGTCTTCCCA TCTGACTTTT GCAGGTCAGT GTATATTACT 
TTCAGTGACT ATGAGAGTGT ACAGGGACTG CCTGCCTTTC GGTATAAAGT TCCTGCAGAA 
ATATTAGCCA ATACGTCAGA CAATGCCGGC TTCTGTATAC CTGAGGGAAA CTGCCTGGGC 
TCAGGAGTTC TGAATGTCAG CATCTGCAAG AATGGTGCAC CCATCATTAT GTCTTTCCCA 
CACTTTTACC AAGCAGATGA GAGGTTTGTT TCTGCCATAG AAGGCATGCA CCCAAATCAG 
GAAGACCATG AGACATTTGT GGACATTAAT CCTTTGACTG GAATAATCCT AAAAGCAGCC 
AAGAGGTTCC AAATCAACAT TTATGTCAAA AAATTAGATG ACTTTGTTGA AACGGGAGAC 
ATTAGAACCA TGGTTTTCCC AGTGATGTAC CTCAATGAGA GTGTTCACAT TGATAAAGAG 
ACGGCGAGTC GACTGAAGTC TATGATTAAC ACTACTTTGA TCATCACCAA CATACCCTAC 
ATCATCATGG CGCTGGGTGT GTTCTTTGGT TTGGTTTTTA CCTGGCTTGC ATGCAAAGGA 
CAGGGATCCA TGGATGAGGG AACAGCGGAT GAAAGAGCAC CCCTCATTCG AACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SCARB2 ( NM_001204255.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001191184.1 Homo sapiens scavenger receptor class B member 2 (SCARB2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu10715
Clone ID Related Accession (Same CDS sequence)	NM_001204255.2 , NM_001204255.1
Accession Version	NM_001204255.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1008bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	lysosome membrane protein 2 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC034139.7, AK296519.1, AK313016.1 and AC110795.4. On May 31, 2019 this sequence version replaced NM_001204255.1. Transcript Variant: This variant (2) lacks three consecutive exons in the CDS, as compared to variant 1. The reading frame is not affected and the resulting isoform (2) lacks an internal segment, as compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK296519.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGGCCGAT GCTGCTTCTA CACGGCGGGG ACGTTGTCCC TGCTCCTGCT GGTGACCAGC 
GTCACGCTGC TGGTGGCCCG GGTCTTCCAG AAGGCTGTAG ACCAGAGTAT CGAGAAGAAA 
ATTGTGTTAA GGAATGGTAC TGAGGCATTT GACTCCTGGG AGAAGCCCCC TCTGCCTGTG 
TATACTCAGT TCTATTTCTT CAATGTCACC AATCCAGAGG AGATCCTCAG AGGGGAGACC 
CCTCGGGTGG AAGAAGTGGG GCCATACACC TACAGGTCAC TTGACTGGTG GATAACAGAC 
AAGTGCAATA TGATTAATGG AACAGATGGA GATTCTTTTC ACCCACTAAT AACCAAAGAT 
GAGGTCCTTT ATGTCTTCCC ATCTGACTTT TGCAGGTCAG TGTATATTAC TTTCAGTGAC 
TATGAGAGTG TACAGGGACT GCCTGCCTTT CGGTATAAAG TTCCTGCAGA AATATTAGCC 
AATACGTCAG ACAATGCCGG CTTCTGTATA CCTGAGGGAA ACTGCCTGGG CTCAGGAGTT 
CTGAATGTCA GCATCTGCAA GAATGGTGCA CCCATCATTA TGTCTTTCCC ACACTTTTAC 
CAAGCAGATG AGAGGTTTGT TTCTGCCATA GAAGGCATGC ACCCAAATCA GGAAGACCAT 
GAGACATTTG TGGACATTAA TCCTTTGACT GGAATAATCC TAAAAGCAGC CAAGAGGTTC 
CAAATCAACA TTTATGTCAA AAAATTAGAT GACTTTGTTG AAACGGGAGA CATTAGAACC 
ATGGTTTTCC CAGTGATGTA CCTCAATGAG AGTGTTCACA TTGATAAAGA GACGGCGAGT 
CGACTGAAGT CTATGATTAA CACTACTTTG ATCATCACCA ACATACCCTA CATCATCATG 
GCGCTGGGTG TGTTCTTTGG TTTGGTTTTT ACCTGGCTTG CATGCAAAGG ACAGGGATCC 
ATGGATGAGG GAACAGCGGA TGAAAGAGCA CCCCTCATTC GAACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001191184.1
CDS	282..1289
Translation	MGRCCFYTAGTLSLLLLVTSVTLLVARVFQKAVDQSIEKKIVLRNGTEAFDSWEKPPLPVYTQFYFFNVTNPEEILRGETPRVEEVGPYTYRSLDWWITDKCNMINGTDGDSFHPLITKDEVLYVFPSDFCRSVYITFSDYESVQGLPAFRYKVPAEILANTSDNAGFCIPEGNCLGSGVLNVSICKNGAPIIMSFPHFYQADERFVSAIEGMHPNQEDHETFVDINPLTGIILKAAKRFQINIYVKKLDDFVETGDIRTMVFPVMYLNESVHIDKETASRLKSMINTTLIITNIPYIIMALGVFFGLVFTWLACKGQGSMDEGTADERAPLIRT

Target ORF information:

RefSeq Version	NM_001204255.2
Organism	Homo sapiens(human)
Definition	Homo sapiens scavenger receptor class B member 2 (SCARB2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001204255.2

ORF Insert Sequence:

ATGGGCCGAT GCTGCTTCTA CACGGCGGGG ACGTTGTCCC TGCTCCTGCT GGTGACCAGC 
GTCACGCTGC TGGTGGCCCG GGTCTTCCAG AAGGCTGTAG ACCAGAGTAT CGAGAAGAAA 
ATTGTGTTAA GGAATGGTAC TGAGGCATTT GACTCCTGGG AGAAGCCCCC TCTGCCTGTG 
TATACTCAGT TCTATTTCTT CAATGTCACC AATCCAGAGG AGATCCTCAG AGGGGAGACC 
CCTCGGGTGG AAGAAGTGGG GCCATACACC TACAGGTCAC TTGACTGGTG GATAACAGAC 
AAGTGCAATA TGATTAATGG AACAGATGGA GATTCTTTTC ACCCACTAAT AACCAAAGAT 
GAGGTCCTTT ATGTCTTCCC ATCTGACTTT TGCAGGTCAG TGTATATTAC TTTCAGTGAC 
TATGAGAGTG TACAGGGACT GCCTGCCTTT CGGTATAAAG TTCCTGCAGA AATATTAGCC 
AATACGTCAG ACAATGCCGG CTTCTGTATA CCTGAGGGAA ACTGCCTGGG CTCAGGAGTT 
CTGAATGTCA GCATCTGCAA GAATGGTGCA CCCATCATTA TGTCTTTCCC ACACTTTTAC 
CAAGCAGATG AGAGGTTTGT TTCTGCCATA GAAGGCATGC ACCCAAATCA GGAAGACCAT 
GAGACATTTG TGGACATTAA TCCTTTGACT GGAATAATCC TAAAAGCAGC CAAGAGGTTC 
CAAATCAACA TTTATGTCAA AAAATTAGAT GACTTTGTTG AAACGGGAGA CATTAGAACC 
ATGGTTTTCC CAGTGATGTA CCTCAATGAG AGTGTTCACA TTGATAAAGA GACGGCGAGT 
CGACTGAAGT CTATGATTAA CACTACTTTG ATCATCACCA ACATACCCTA CATCATCATG 
GCGCTGGGTG TGTTCTTTGG TTTGGTTTTT ACCTGGCTTG CATGCAAAGG ACAGGGATCC 
ATGGATGAGG GAACAGCGGA TGAAAGAGCA CCCCTCATTC GAACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SCARB2 ( NM_001204255.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001191184.1 Homo sapiens scavenger receptor class B member 2 (SCARB2), transcript variant 2, mRNA.

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CloneID	OHu10715
Clone ID Related Accession (Same CDS sequence)	NM_001204255.2 , NM_001204255.1
Accession Version	NM_001204255.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1008bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	lysosome membrane protein 2 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC034139.7, AK296519.1, AK313016.1 and AC110795.4. Transcript Variant: This variant (2) lacks three consecutive exons in the CDS, as compared to variant 1. The reading frame is not affected and the resulting isoform (2) lacks an internal segment, as compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK296519.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGGCCGAT GCTGCTTCTA CACGGCGGGG ACGTTGTCCC TGCTCCTGCT GGTGACCAGC 
GTCACGCTGC TGGTGGCCCG GGTCTTCCAG AAGGCTGTAG ACCAGAGTAT CGAGAAGAAA 
ATTGTGTTAA GGAATGGTAC TGAGGCATTT GACTCCTGGG AGAAGCCCCC TCTGCCTGTG 
TATACTCAGT TCTATTTCTT CAATGTCACC AATCCAGAGG AGATCCTCAG AGGGGAGACC 
CCTCGGGTGG AAGAAGTGGG GCCATACACC TACAGGTCAC TTGACTGGTG GATAACAGAC 
AAGTGCAATA TGATTAATGG AACAGATGGA GATTCTTTTC ACCCACTAAT AACCAAAGAT 
GAGGTCCTTT ATGTCTTCCC ATCTGACTTT TGCAGGTCAG TGTATATTAC TTTCAGTGAC 
TATGAGAGTG TACAGGGACT GCCTGCCTTT CGGTATAAAG TTCCTGCAGA AATATTAGCC 
AATACGTCAG ACAATGCCGG CTTCTGTATA CCTGAGGGAA ACTGCCTGGG CTCAGGAGTT 
CTGAATGTCA GCATCTGCAA GAATGGTGCA CCCATCATTA TGTCTTTCCC ACACTTTTAC 
CAAGCAGATG AGAGGTTTGT TTCTGCCATA GAAGGCATGC ACCCAAATCA GGAAGACCAT 
GAGACATTTG TGGACATTAA TCCTTTGACT GGAATAATCC TAAAAGCAGC CAAGAGGTTC 
CAAATCAACA TTTATGTCAA AAAATTAGAT GACTTTGTTG AAACGGGAGA CATTAGAACC 
ATGGTTTTCC CAGTGATGTA CCTCAATGAG AGTGTTCACA TTGATAAAGA GACGGCGAGT 
CGACTGAAGT CTATGATTAA CACTACTTTG ATCATCACCA ACATACCCTA CATCATCATG 
GCGCTGGGTG TGTTCTTTGG TTTGGTTTTT ACCTGGCTTG CATGCAAAGG ACAGGGATCC 
ATGGATGAGG GAACAGCGGA TGAAAGAGCA CCCCTCATTC GAACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001191184.1
CDS	357..1364
Translation	MGRCCFYTAGTLSLLLLVTSVTLLVARVFQKAVDQSIEKKIVLRNGTEAFDSWEKPPLPVYTQFYFFNVTNPEEILRGETPRVEEVGPYTYRSLDWWITDKCNMINGTDGDSFHPLITKDEVLYVFPSDFCRSVYITFSDYESVQGLPAFRYKVPAEILANTSDNAGFCIPEGNCLGSGVLNVSICKNGAPIIMSFPHFYQADERFVSAIEGMHPNQEDHETFVDINPLTGIILKAAKRFQINIYVKKLDDFVETGDIRTMVFPVMYLNESVHIDKETASRLKSMINTTLIITNIPYIIMALGVFFGLVFTWLACKGQGSMDEGTADERAPLIRT

Target ORF information:

RefSeq Version	NM_001204255.1
Organism	Homo sapiens(human)
Definition	Homo sapiens scavenger receptor class B member 2 (SCARB2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001204255.1

ORF Insert Sequence:

ATGGGCCGAT GCTGCTTCTA CACGGCGGGG ACGTTGTCCC TGCTCCTGCT GGTGACCAGC 
GTCACGCTGC TGGTGGCCCG GGTCTTCCAG AAGGCTGTAG ACCAGAGTAT CGAGAAGAAA 
ATTGTGTTAA GGAATGGTAC TGAGGCATTT GACTCCTGGG AGAAGCCCCC TCTGCCTGTG 
TATACTCAGT TCTATTTCTT CAATGTCACC AATCCAGAGG AGATCCTCAG AGGGGAGACC 
CCTCGGGTGG AAGAAGTGGG GCCATACACC TACAGGTCAC TTGACTGGTG GATAACAGAC 
AAGTGCAATA TGATTAATGG AACAGATGGA GATTCTTTTC ACCCACTAAT AACCAAAGAT 
GAGGTCCTTT ATGTCTTCCC ATCTGACTTT TGCAGGTCAG TGTATATTAC TTTCAGTGAC 
TATGAGAGTG TACAGGGACT GCCTGCCTTT CGGTATAAAG TTCCTGCAGA AATATTAGCC 
AATACGTCAG ACAATGCCGG CTTCTGTATA CCTGAGGGAA ACTGCCTGGG CTCAGGAGTT 
CTGAATGTCA GCATCTGCAA GAATGGTGCA CCCATCATTA TGTCTTTCCC ACACTTTTAC 
CAAGCAGATG AGAGGTTTGT TTCTGCCATA GAAGGCATGC ACCCAAATCA GGAAGACCAT 
GAGACATTTG TGGACATTAA TCCTTTGACT GGAATAATCC TAAAAGCAGC CAAGAGGTTC 
CAAATCAACA TTTATGTCAA AAAATTAGAT GACTTTGTTG AAACGGGAGA CATTAGAACC 
ATGGTTTTCC CAGTGATGTA CCTCAATGAG AGTGTTCACA TTGATAAAGA GACGGCGAGT 
CGACTGAAGT CTATGATTAA CACTACTTTG ATCATCACCA ACATACCCTA CATCATCATG 
GCGCTGGGTG TGTTCTTTGG TTTGGTTTTT ACCTGGCTTG CATGCAAAGG ACAGGGATCC 
ATGGATGAGG GAACAGCGGA TGAAAGAGCA CCCCTCATTC GAACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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SCARB2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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