KIF3B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KIF3B
Entrez Gene ID	9371
Full Name	kinesin family member 3B
Synonyms	FLA8,HH0048,KLP-11
General protein information	Preferred Names kinesin family member 3B Names kinesin-like protein KIF3B microtubule plus end-directed kinesin motor 3B
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20q11.21
Summary	The protein encoded by this gene acts as a heterodimer with kinesin family member 3A to aid in chromosome movement during mitosis and meiosis. The encoded protein is a plus end-directed microtubule motor and can interact with the SMC3 subunit of the cohesin complex. In addition, the encoded protein may be involved in the intracellular movement of membranous organelles. This protein and kinesin family member 3A form the kinesin II subfamily of the kinesin superfamily. [provided by RefSeq, Jul 2008].
Disorder MIM:	603754

mRNA and Protein(s)

mRNA	Protein	Name
NM_004798.3	NP_004789.1	kinesin-like protein KIF3B
NM_004798.4	NP_004789.1	kinesin-like protein KIF3B

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Kif3b	NP_032470.3
Xenopus tropicalis (tropical clawed frog)	kif3b	XP_004918676.1
Danio rerio (zebrafish)	kif3b	NP_001093615.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010396	XP_311552.4
Homo sapiens (human)	KIF3B	NP_004789.1
	KIF3B	XP_001108420.1
Bos taurus (cattle)	KIF3B	NP_001104258.1
Gallus gallus (chicken)	KIF3B	NP_001012852.1
Caenorhabditis elegans (roundworm)	klp-11	NP_741473.1
Pan troglodytes (chimpanzee)	KIF3B	XP_001155482.1
Canis lupus familiaris (dog)	KIF3B	XP_005634978.1
Rattus norvegicus (Norway rat)	Kif3b	NP_001099999.1
Drosophila melanogaster (fruit fly)	Klp68D	NP_001261726.1

Gene Ontology
Bibliography

Related articles in PubMed

Intraflagellar transport velocity is governed by the number of active KIF17 and KIF3AB motors and their motility properties under load.
Milic B, Andreasson JOL, Hogan DW, Block SM
Proceedings of the National Academy of Sciences of the United States of America114(33)E6830-E6838(2017 Aug)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

A novel role of KIF3b in the seminoma cell cycle.
Shen HQ, Xiao YX, She ZY, Tan FQ, Yang WX
Experimental cell research352(1)95-103(2017 03)

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Boldt K, van Reeuwijk J, Lu Q, Koutroumpas K, Nguyen TM, Texier Y, van Beersum SE, Horn N, Willer JR, Mans DA, Dougherty G, Lamers IJ, Coene KL, Arts HH, Betts MJ, Beyer T, Bolat E, Gloeckner CJ, Haidari K, Hetterschijt L, Iaconis D, Jenkins D, Klose F, Knapp B, Latour B, Letteboer SJ, Marcelis CL, Mitic D, Morleo M, Oud MM, Riemersma M, Rix S, Terhal PA, Toedt G, van Dam TJ, de Vrieze E, Wissinger Y, Wu KM, Apic G, Beales PL, Blacque OE, Gibson TJ, Huynen MA, Katsanis N, Kremer H, Omran H, van Wijk E, Wolfrum U, Kepes F, Davis EE, Franco B, Giles RH, Ueffing M, Russell RB, Roepman R,
Nature communications711491(2016 May)

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M
Cell163(3)712-23(2015 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

High KIF3B expression is associated with seminoma.
Title: A novel role of KIF3b in the seminoma cell cycle.

These data suggest that GLI interactions with KIF3A-KIF3B-KAP3 complexes are essential for proper GLI transcriptional activity.
Title: The heterotrimeric kinesin-2 complex interacts with and regulates GLI protein function.

Results suggest that KIF3B expression was upregulated in HCC tumor tissues and proliferating HCC cells, and an increasd KIF3B expression was associated with poor overall survival.
Title: Suppression of KIF3B expression inhibits human hepatocellular carcinoma proliferation.

KIF3B is involved in the trafficking of kAE1 to the plasma membrane of human kidney alpha-intercalated cells.
Title: Human kidney anion exchanger 1 interacts with kinesin family member 3B (KIF3B).

Interaction with KIF3B alters CLC-5 cell surface expression, chloride current, and alters albumin endocytosis. Interaction with KIF3B facilitates microtubular transport and endocytosis of CLC-5-containing vesicles away from cell surface.
Title: CLC-5 and KIF3B interact to facilitate CLC-5 plasma membrane expression, endocytosis, and microtubular transport: relevance to pathophysiology of Dent's disease.

The following KIF3B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KIF3B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu12346	NM_004798.4 Latest version!	Homo sapiens kinesin family member 3B (KIF3B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
View Old Accession Versions >>
OHu12346	NM_004798.3	Homo sapiens kinesin family member 3B (KIF3B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KIF3B ( NM_004798.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004789.1 Homo sapiens kinesin family member 3B (KIF3B), mRNA.

Price & Availability↑

CloneID	OHu12346
Clone ID Related Accession (Same CDS sequence)	NM_004798.3 , NM_004798.4
Accession Version	NM_004798.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2244bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	kinesin-like protein KIF3B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA805755.1, AB002357.1, BC136311.1, AL121897.32, AL354800.4 and AL353976.1. On Jul 8, 2010 this sequence version replaced NM_004798.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB002357.1, SRR1660803.189755.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCAAAGT TGAAAAGCTC AGAGTCAGTC AGGGTGGTGG TTCGCTGTCG GCCCATGAAT 
GGCAAGGAAA AGGCTGCTTC GTATGACAAA GTGGTGGATG TGGATGTTAA GCTGGGGCAG 
GTGTCTGTGA AGAACCCCAA AGGGACGGCC CATGAAATGC CCAAGACCTT CACCTTTGAT 
GCCGTCTATG ACTGGAATGC CAAGCAGTTT GAACTGTACG ATGAGACGTT CCGACCACTT 
GTTGACTCTG TCCTGCAAGG TTTCAATGGA ACCATTTTTG CCTATGGACA AACTGGGACA 
GGAAAAACCT ACACCATGGA AGGAATCCGT GGTGACCCTG AAAAAAGAGG AGTCATTCCT 
AACTCATTTG ACCATATCTT CACCCACATC TCTCGATCCC AGAATCAACA ATACCTGGTC 
AGGGCTTCTT ACTTAGAGAT CTACCAGGAG GAGATCCGAG ATTTGCTCTC AAAGGATCAG 
ACCAAAAGGC TTGAGCTCAA AGAGAGGCCT GACACAGGAG TGTATGTGAA AGACCTGTCT 
TCCTTTGTCA CCAAGAGTGT GAAGGAGATA GAGCATGTGA TGAATGTGGG GAACCAGAAC 
CGTTCTGTCG GTGCTACCAA CATGAACGAG CACAGCTCGC GTTCTCATGC AATTTTCGTT 
ATCACTATTG AGTGCAGCGA GGTGGGCCTC GATGGTGAAA ACCACATCCG TGTAGGAAAA 
TTGAACCTTG TAGATCTTGC TGGCAGCGAA CGGCAAGCCA AGACCGGCGC ACAAGGGGAG 
AGATTAAAAG AAGCTACCAA GATCAACCTC TCCCTTTCCG CTTTGGGTAA TGTCATCTCT 
GCTCTAGTGG ACGGCAAAAG CACTCACATT CCATATCGGG ACTCAAAGCT TACCAGGCTC 
CTCCAAGATT CCCTTGGTGG CAATGCCAAG ACTGTGATGG TGGCCAACGT GGGGCCTGCC 
TCTTACAACG TAGAAGAGAC TCTGACCACT CTGCGATATG CCAACCGTGC CAAAAACATT 
AAGAACAAAC CAAGGGTCAA TGAGGACCCC AAGGATGCCC TCCTTCGAGA ATTCCAGGAA 
GAGATTGCTC GGCTCAAGGC CCAGCTGGAA AAACGGTCCA TTGGTAGGAG GAAGAGGCGA 
GAGAAGCGGA GGGAAGGTGG TGGCAGTGGT GGGGGTGGGG AAGAGGAGGA GGAGGAGGGA 
GAAGAGGGTG AGGAGGAAGG GGATGATAAG GATGATTACT GGCGGGAACA GCAAGAAAAA 
CTGGAGATTG AGAAGCGGGC CATTGTAGAG GATCACAGCT TGGTTGCAGA GGAGAAGATG 
AGGCTGCTGA AGGAGAAAGA GAAAAAGATG GAGGACCTGC GGCGGGAGAA GGATGCTGCC 
GAGATGCTGG GCGCCAAGAT CAAGGCCATG GAGAGTAAGT TGCTTGTTGG AGGAAAAAAT 
ATAGTAGATC ATACGAATGA ACAGCAGAAA ATCCTGGAGC AGAAACGACA GGAAATTGCA 
GAGCAGAAAC GTCGAGAAAG AGAAATCCAG CAACAGATGG AAAGTCGAGA TGAGGAGACC 
TTGGAACTTA AAGAGACATA CAGCTCATTG CAGCAAGAGG TGGACATCAA GACCAAAAAA 
CTCAAAAAGC TCTTCTCCAA GCTTCAGGCA GTGAAGGCTG AGATCCATGA CCTCCAAGAA 
GAACACATCA AGGAGCGCCA AGAGCTAGAG CAGACTCAGA ATGAGCTCAC CAGGGAGCTG 
AAACTCAAGC ATCTTATTAT AGAAAACTTT ATCCCTCTGG AAGAAAAAAG TAAAATTATG 
AATAGAGCCT TCTTTGATGA AGAGGAAGAT CATTGGAAAC TACATCCTAT AACCAGACTG 
GAGAACCAGC AGATGATGAA GCGGCCAGTC TCAGCCGTGG GATATAAGAG ACCATTGAGC 
CAGCACGCAA GAATGTCCAT GATGATTCGT CCAGAGGCCC GATATAGGGC AGAAAACATT 
GTGCTGTTAG AGCTGGACAT GCCCAGCCGG ACCACCAGAG ACTATGAGGG TCCAGCCATT 
GCCCCCAAGG TCCAGGCTGC ATTGGATGCG GCTCTGCAGG ATGAAGATGA GATACAGGTG 
GATGCATCAT CATTTGAAAG CACTGCAAAT AAGAAATCCA AGGCCAGGCC TAAAAGTGGA 
AGGAAGTCGG GATCCTCCTC CTCTTCCTCA GGAACCCCTG CATCTCAGCT TTATCCACAG 
TCTCGGGGGC TGGTTCCAAA GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004789.1
CDS	181..2424
Translation	MSKLKSSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIPNSFDHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIPLEEKSKIMNRAFFDEEEDHWKLHPITRLENQQMMKRPVSAVGYKRPLSQHARMSMMIRPEARYRAENIVLLELDMPSRTTRDYEGPAIAPKVQAALDAALQDEDEIQVDASSFESTANKKSKARPKSGRKSGSSSSSSGTPASQLYPQSRGLVPK

Target ORF information:

RefSeq Version	NM_004798.3
Organism	Homo sapiens(human)
Definition	Homo sapiens kinesin family member 3B (KIF3B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004798.3

ORF Insert Sequence:

ATGTCAAAGT TGAAAAGCTC AGAGTCAGTC AGGGTGGTGG TTCGCTGTCG GCCCATGAAT 
GGCAAGGAAA AGGCTGCTTC GTATGACAAA GTGGTGGATG TGGATGTTAA GCTGGGGCAG 
GTGTCTGTGA AGAACCCCAA AGGGACGGCC CATGAAATGC CCAAGACCTT CACCTTTGAT 
GCCGTCTATG ACTGGAATGC CAAGCAGTTT GAACTGTACG ATGAGACGTT CCGACCACTT 
GTTGACTCTG TCCTGCAAGG TTTCAATGGA ACCATTTTTG CCTATGGACA AACTGGGACA 
GGAAAAACCT ACACCATGGA AGGAATCCGT GGTGACCCTG AAAAAAGAGG AGTCATTCCT 
AACTCATTTG ACCATATCTT CACCCACATC TCTCGATCCC AGAATCAACA ATACCTGGTC 
AGGGCTTCTT ACTTAGAGAT CTACCAGGAG GAGATCCGAG ATTTGCTCTC AAAGGATCAG 
ACCAAAAGGC TTGAGCTCAA AGAGAGGCCT GACACAGGAG TGTATGTGAA AGACCTGTCT 
TCCTTTGTCA CCAAGAGTGT GAAGGAGATA GAGCATGTGA TGAATGTGGG GAACCAGAAC 
CGTTCTGTCG GTGCTACCAA CATGAACGAG CACAGCTCGC GTTCTCATGC AATTTTCGTT 
ATCACTATTG AGTGCAGCGA GGTGGGCCTC GATGGTGAAA ACCACATCCG TGTAGGAAAA 
TTGAACCTTG TAGATCTTGC TGGCAGCGAA CGGCAAGCCA AGACCGGCGC ACAAGGGGAG 
AGATTAAAAG AAGCTACCAA GATCAACCTC TCCCTTTCCG CTTTGGGTAA TGTCATCTCT 
GCTCTAGTGG ACGGCAAAAG CACTCACATT CCATATCGGG ACTCAAAGCT TACCAGGCTC 
CTCCAAGATT CCCTTGGTGG CAATGCCAAG ACTGTGATGG TGGCCAACGT GGGGCCTGCC 
TCTTACAACG TAGAAGAGAC TCTGACCACT CTGCGATATG CCAACCGTGC CAAAAACATT 
AAGAACAAAC CAAGGGTCAA TGAGGACCCC AAGGATGCCC TCCTTCGAGA ATTCCAGGAA 
GAGATTGCTC GGCTCAAGGC CCAGCTGGAA AAACGGTCCA TTGGTAGGAG GAAGAGGCGA 
GAGAAGCGGA GGGAAGGTGG TGGCAGTGGT GGGGGTGGGG AAGAGGAGGA GGAGGAGGGA 
GAAGAGGGTG AGGAGGAAGG GGATGATAAG GATGATTACT GGCGGGAACA GCAAGAAAAA 
CTGGAGATTG AGAAGCGGGC CATTGTAGAG GATCACAGCT TGGTTGCAGA GGAGAAGATG 
AGGCTGCTGA AGGAGAAAGA GAAAAAGATG GAGGACCTGC GGCGGGAGAA GGATGCTGCC 
GAGATGCTGG GCGCCAAGAT CAAGGCCATG GAGAGTAAGT TGCTTGTTGG AGGAAAAAAT 
ATAGTAGATC ATACGAATGA ACAGCAGAAA ATCCTGGAGC AGAAACGACA GGAAATTGCA 
GAGCAGAAAC GTCGAGAAAG AGAAATCCAG CAACAGATGG AAAGTCGAGA TGAGGAGACC 
TTGGAACTTA AAGAGACATA CAGCTCATTG CAGCAAGAGG TGGACATCAA GACCAAAAAA 
CTCAAAAAGC TCTTCTCCAA GCTTCAGGCA GTGAAGGCTG AGATCCATGA CCTCCAAGAA 
GAACACATCA AGGAGCGCCA AGAGCTAGAG CAGACTCAGA ATGAGCTCAC CAGGGAGCTG 
AAACTCAAGC ATCTTATTAT AGAAAACTTT ATCCCTCTGG AAGAAAAAAG TAAAATTATG 
AATAGAGCCT TCTTTGATGA AGAGGAAGAT CATTGGAAAC TACATCCTAT AACCAGACTG 
GAGAACCAGC AGATGATGAA GCGGCCAGTC TCAGCCGTGG GATATAAGAG ACCATTGAGC 
CAGCACGCAA GAATGTCCAT GATGATTCGT CCAGAGGCCC GATATAGGGC AGAAAACATT 
GTGCTGTTAG AGCTGGACAT GCCCAGCCGG ACCACCAGAG ACTATGAGGG TCCAGCCATT 
GCCCCCAAGG TCCAGGCTGC ATTGGATGCG GCTCTGCAGG ATGAAGATGA GATACAGGTG 
GATGCATCAT CATTTGAAAG CACTGCAAAT AAGAAATCCA AGGCCAGGCC TAAAAGTGGA 
AGGAAGTCGG GATCCTCCTC CTCTTCCTCA GGAACCCCTG CATCTCAGCT TTATCCACAG 
TCTCGGGGGC TGGTTCCAAA GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KIF3B ( NM_004798.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_004789.1 Homo sapiens kinesin family member 3B (KIF3B), mRNA.

Price & Availability↑

CloneID	OHu12346
Clone ID Related Accession (Same CDS sequence)	NM_004798.3 , NM_004798.4
Accession Version	NM_004798.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2244bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	kinesin-like protein KIF3B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA805755.1, AB002357.1, BC136311.1, AL121897.32, AL354800.4 and AL353976.1. On Nov 22, 2018 this sequence version replaced NM_004798.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB002357.1, SRR1660803.189755.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000375712.4/ ENSP00000364864.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCAAAGT TGAAAAGCTC AGAGTCAGTC AGGGTGGTGG TTCGCTGTCG GCCCATGAAT 
GGCAAGGAAA AGGCTGCTTC GTATGACAAA GTGGTGGATG TGGATGTTAA GCTGGGGCAG 
GTGTCTGTGA AGAACCCCAA AGGGACGGCC CATGAAATGC CCAAGACCTT CACCTTTGAT 
GCCGTCTATG ACTGGAATGC CAAGCAGTTT GAACTGTACG ATGAGACGTT CCGACCACTT 
GTTGACTCTG TCCTGCAAGG TTTCAATGGA ACCATTTTTG CCTATGGACA AACTGGGACA 
GGAAAAACCT ACACCATGGA AGGAATCCGT GGTGACCCTG AAAAAAGAGG AGTCATTCCT 
AACTCATTTG ACCATATCTT CACCCACATC TCTCGATCCC AGAATCAACA ATACCTGGTC 
AGGGCTTCTT ACTTAGAGAT CTACCAGGAG GAGATCCGAG ATTTGCTCTC AAAGGATCAG 
ACCAAAAGGC TTGAGCTCAA AGAGAGGCCT GACACAGGAG TGTATGTGAA AGACCTGTCT 
TCCTTTGTCA CCAAGAGTGT GAAGGAGATA GAGCATGTGA TGAATGTGGG GAACCAGAAC 
CGTTCTGTCG GTGCTACCAA CATGAACGAG CACAGCTCGC GTTCTCATGC AATTTTCGTT 
ATCACTATTG AGTGCAGCGA GGTGGGCCTC GATGGTGAAA ACCACATCCG TGTAGGAAAA 
TTGAACCTTG TAGATCTTGC TGGCAGCGAA CGGCAAGCCA AGACCGGCGC ACAAGGGGAG 
AGATTAAAAG AAGCTACCAA GATCAACCTC TCCCTTTCCG CTTTGGGTAA TGTCATCTCT 
GCTCTAGTGG ACGGCAAAAG CACTCACATT CCATATCGGG ACTCAAAGCT TACCAGGCTC 
CTCCAAGATT CCCTTGGTGG CAATGCCAAG ACTGTGATGG TGGCCAACGT GGGGCCTGCC 
TCTTACAACG TAGAAGAGAC TCTGACCACT CTGCGATATG CCAACCGTGC CAAAAACATT 
AAGAACAAAC CAAGGGTCAA TGAGGACCCC AAGGATGCCC TCCTTCGAGA ATTCCAGGAA 
GAGATTGCTC GGCTCAAGGC CCAGCTGGAA AAACGGTCCA TTGGTAGGAG GAAGAGGCGA 
GAGAAGCGGA GGGAAGGTGG TGGCAGTGGT GGGGGTGGGG AAGAGGAGGA GGAGGAGGGA 
GAAGAGGGTG AGGAGGAAGG GGATGATAAG GATGATTACT GGCGGGAACA GCAAGAAAAA 
CTGGAGATTG AGAAGCGGGC CATTGTAGAG GATCACAGCT TGGTTGCAGA GGAGAAGATG 
AGGCTGCTGA AGGAGAAAGA GAAAAAGATG GAGGACCTGC GGCGGGAGAA GGATGCTGCC 
GAGATGCTGG GCGCCAAGAT CAAGGCCATG GAGAGTAAGT TGCTTGTTGG AGGAAAAAAT 
ATAGTAGATC ATACGAATGA ACAGCAGAAA ATCCTGGAGC AGAAACGACA GGAAATTGCA 
GAGCAGAAAC GTCGAGAAAG AGAAATCCAG CAACAGATGG AAAGTCGAGA TGAGGAGACC 
TTGGAACTTA AAGAGACATA CAGCTCATTG CAGCAAGAGG TGGACATCAA GACCAAAAAA 
CTCAAAAAGC TCTTCTCCAA GCTTCAGGCA GTGAAGGCTG AGATCCATGA CCTCCAAGAA 
GAACACATCA AGGAGCGCCA AGAGCTAGAG CAGACTCAGA ATGAGCTCAC CAGGGAGCTG 
AAACTCAAGC ATCTTATTAT AGAAAACTTT ATCCCTCTGG AAGAAAAAAG TAAAATTATG 
AATAGAGCCT TCTTTGATGA AGAGGAAGAT CATTGGAAAC TACATCCTAT AACCAGACTG 
GAGAACCAGC AGATGATGAA GCGGCCAGTC TCAGCCGTGG GATATAAGAG ACCATTGAGC 
CAGCACGCAA GAATGTCCAT GATGATTCGT CCAGAGGCCC GATATAGGGC AGAAAACATT 
GTGCTGTTAG AGCTGGACAT GCCCAGCCGG ACCACCAGAG ACTATGAGGG TCCAGCCATT 
GCCCCCAAGG TCCAGGCTGC ATTGGATGCG GCTCTGCAGG ATGAAGATGA GATACAGGTG 
GATGCATCAT CATTTGAAAG CACTGCAAAT AAGAAATCCA AGGCCAGGCC TAAAAGTGGA 
AGGAAGTCGG GATCCTCCTC CTCTTCCTCA GGAACCCCTG CATCTCAGCT TTATCCACAG 
TCTCGGGGGC TGGTTCCAAA GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004789.1
CDS	181..2424
Translation	MSKLKSSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIPNSFDHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIPLEEKSKIMNRAFFDEEEDHWKLHPITRLENQQMMKRPVSAVGYKRPLSQHARMSMMIRPEARYRAENIVLLELDMPSRTTRDYEGPAIAPKVQAALDAALQDEDEIQVDASSFESTANKKSKARPKSGRKSGSSSSSSGTPASQLYPQSRGLVPK

Target ORF information:

RefSeq Version	NM_004798.4
Organism	Homo sapiens(human)
Definition	Homo sapiens kinesin family member 3B (KIF3B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004798.4

ORF Insert Sequence:

ATGTCAAAGT TGAAAAGCTC AGAGTCAGTC AGGGTGGTGG TTCGCTGTCG GCCCATGAAT 
GGCAAGGAAA AGGCTGCTTC GTATGACAAA GTGGTGGATG TGGATGTTAA GCTGGGGCAG 
GTGTCTGTGA AGAACCCCAA AGGGACGGCC CATGAAATGC CCAAGACCTT CACCTTTGAT 
GCCGTCTATG ACTGGAATGC CAAGCAGTTT GAACTGTACG ATGAGACGTT CCGACCACTT 
GTTGACTCTG TCCTGCAAGG TTTCAATGGA ACCATTTTTG CCTATGGACA AACTGGGACA 
GGAAAAACCT ACACCATGGA AGGAATCCGT GGTGACCCTG AAAAAAGAGG AGTCATTCCT 
AACTCATTTG ACCATATCTT CACCCACATC TCTCGATCCC AGAATCAACA ATACCTGGTC 
AGGGCTTCTT ACTTAGAGAT CTACCAGGAG GAGATCCGAG ATTTGCTCTC AAAGGATCAG 
ACCAAAAGGC TTGAGCTCAA AGAGAGGCCT GACACAGGAG TGTATGTGAA AGACCTGTCT 
TCCTTTGTCA CCAAGAGTGT GAAGGAGATA GAGCATGTGA TGAATGTGGG GAACCAGAAC 
CGTTCTGTCG GTGCTACCAA CATGAACGAG CACAGCTCGC GTTCTCATGC AATTTTCGTT 
ATCACTATTG AGTGCAGCGA GGTGGGCCTC GATGGTGAAA ACCACATCCG TGTAGGAAAA 
TTGAACCTTG TAGATCTTGC TGGCAGCGAA CGGCAAGCCA AGACCGGCGC ACAAGGGGAG 
AGATTAAAAG AAGCTACCAA GATCAACCTC TCCCTTTCCG CTTTGGGTAA TGTCATCTCT 
GCTCTAGTGG ACGGCAAAAG CACTCACATT CCATATCGGG ACTCAAAGCT TACCAGGCTC 
CTCCAAGATT CCCTTGGTGG CAATGCCAAG ACTGTGATGG TGGCCAACGT GGGGCCTGCC 
TCTTACAACG TAGAAGAGAC TCTGACCACT CTGCGATATG CCAACCGTGC CAAAAACATT 
AAGAACAAAC CAAGGGTCAA TGAGGACCCC AAGGATGCCC TCCTTCGAGA ATTCCAGGAA 
GAGATTGCTC GGCTCAAGGC CCAGCTGGAA AAACGGTCCA TTGGTAGGAG GAAGAGGCGA 
GAGAAGCGGA GGGAAGGTGG TGGCAGTGGT GGGGGTGGGG AAGAGGAGGA GGAGGAGGGA 
GAAGAGGGTG AGGAGGAAGG GGATGATAAG GATGATTACT GGCGGGAACA GCAAGAAAAA 
CTGGAGATTG AGAAGCGGGC CATTGTAGAG GATCACAGCT TGGTTGCAGA GGAGAAGATG 
AGGCTGCTGA AGGAGAAAGA GAAAAAGATG GAGGACCTGC GGCGGGAGAA GGATGCTGCC 
GAGATGCTGG GCGCCAAGAT CAAGGCCATG GAGAGTAAGT TGCTTGTTGG AGGAAAAAAT 
ATAGTAGATC ATACGAATGA ACAGCAGAAA ATCCTGGAGC AGAAACGACA GGAAATTGCA 
GAGCAGAAAC GTCGAGAAAG AGAAATCCAG CAACAGATGG AAAGTCGAGA TGAGGAGACC 
TTGGAACTTA AAGAGACATA CAGCTCATTG CAGCAAGAGG TGGACATCAA GACCAAAAAA 
CTCAAAAAGC TCTTCTCCAA GCTTCAGGCA GTGAAGGCTG AGATCCATGA CCTCCAAGAA 
GAACACATCA AGGAGCGCCA AGAGCTAGAG CAGACTCAGA ATGAGCTCAC CAGGGAGCTG 
AAACTCAAGC ATCTTATTAT AGAAAACTTT ATCCCTCTGG AAGAAAAAAG TAAAATTATG 
AATAGAGCCT TCTTTGATGA AGAGGAAGAT CATTGGAAAC TACATCCTAT AACCAGACTG 
GAGAACCAGC AGATGATGAA GCGGCCAGTC TCAGCCGTGG GATATAAGAG ACCATTGAGC 
CAGCACGCAA GAATGTCCAT GATGATTCGT CCAGAGGCCC GATATAGGGC AGAAAACATT 
GTGCTGTTAG AGCTGGACAT GCCCAGCCGG ACCACCAGAG ACTATGAGGG TCCAGCCATT 
GCCCCCAAGG TCCAGGCTGC ATTGGATGCG GCTCTGCAGG ATGAAGATGA GATACAGGTG 
GATGCATCAT CATTTGAAAG CACTGCAAAT AAGAAATCCA AGGCCAGGCC TAAAAGTGGA 
AGGAAGTCGG GATCCTCCTC CTCTTCCTCA GGAACCCCTG CATCTCAGCT TTATCCACAG 
TCTCGGGGGC TGGTTCCAAA GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Intraflagellar transport velocity is governed by the number of active KIF17 and KIF3AB motors and their motility properties under load.
Proceedings of the National Academy of Sciences of the United States of America114(33)E6830-E6838(2017 Aug)
Milic B,Andreasson JOL,Hogan DW,Block SM

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

A novel role of KIF3b in the seminoma cell cycle.
Experimental cell research352(1)95-103(2017 03)
Shen HQ,Xiao YX,She ZY,Tan FQ,Yang WX

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Nature communications711491(2016 May)
Boldt K,van Reeuwijk J,Lu Q,Koutroumpas K,Nguyen TM,Texier Y,van Beersum SE,Horn N,Willer JR,Mans DA,Dougherty G,Lamers IJ,Coene KL,Arts HH,Betts MJ,Beyer T,Bolat E,Gloeckner CJ,Haidari K,Hetterschijt L,Iaconis D,Jenkins D,Klose F,Knapp B,Latour B,Letteboer SJ,Marcelis CL,Mitic D,Morleo M,Oud MM,Riemersma M,Rix S,Terhal PA,Toedt G,van Dam TJ,de Vrieze E,Wissinger Y,Wu KM,Apic G,Beales PL,Blacque OE,Gibson TJ,Huynen MA,Katsanis N,Kremer H,Omran H,van Wijk E,Wolfrum U,Kepes F,Davis EE,Franco B,Giles RH,Ueffing M,Russell RB,Roepman R,

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Cell163(3)712-23(2015 Oct)
Hein MY,Hubner NC,Poser I,Cox J,Nagaraj N,Toyoda Y,Gak IA,Weisswange I,Mansfeld J,Buchholz F,Hyman AA,Mann M

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KIF3B cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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