Gene Symbol | AIP |
Entrez Gene ID | 9049 |
Full Name | aryl hydrocarbon receptor interacting protein |
Synonyms | ARA9,FKBP16,FKBP37,PITA1,SMTPHN,XAP-2,XAP2 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]. |
Disorder MIM: | |
Disorder Html: | Pituitary adenoma 1, multiple types, 102200 (3); Pituitary adenoma predisposition, 102000 (3) |