STBD1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	STBD1
Entrez Gene ID	8987
Full Name	starch binding domain 1
Synonyms	GENEX3414,GENX-3414
General protein information	Preferred Names starch binding domain 1 Names starch-binding domain-containing protein 1 genethonin 1 glycophagy cargo receptor STBD1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4q21.1
Disorder MIM:	607406

mRNA and Protein(s)

mRNA	Protein	Name
NM_003943.4	NP_003934.1	starch-binding domain-containing protein 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	STBD1	NP_003934.1
Canis lupus familiaris (dog)	STBD1	XP_005639384.1
Mus musculus (house mouse)	Stbd1	NP_780305.1
	STBD1	XP_002804120.1
Rattus norvegicus (Norway rat)	Stbd1	NP_001014010.1
Pan troglodytes (chimpanzee)	STBD1	XP_003310378.1
Bos taurus (cattle)	STBD1	XP_002688403.1

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Starch Binding Domain-containing Protein 1 Plays a Dominant Role in Glycogen Transport to Lysosomes in Liver.
Sun T, Yi H, Yang C, Kishnani PS, Sun B
The Journal of biological chemistry291(32)16479-84(2016 08)

The carbohydrate-binding domain of overexpressed STBD1 is important for its stability and protein-protein interactions.
Zhu Y, Zhang M, Kelly AR, Cheng A
Bioscience reports34(4)(2014 Jul)

Starch-binding domain-containing protein 1 (Stbd1) and glycogen metabolism: Identification of the Atg8 family interacting motif (AIM) in Stbd1 required for interaction with GABARAPL1.
Jiang S, Wells CD, Roach PJ
Biochemical and biophysical research communications413(3)420-5(2011 Sep)

Starch binding domain-containing protein 1/genethonin 1 is a novel participant in glycogen metabolism.
Jiang S, Heller B, Tagliabracci VS, Zhai L, Irimia JM, DePaoli-Roach AA, Wells CD, Skurat AV, Roach PJ
The Journal of biological chemistry285(45)34960-71(2010 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

results demonstrate that Stbd1 plays a dominant role in glycogen transport to lysosomes in liver and that the N-terminal transmembrane region and the C-terminal CBM20 domain are critical for this function.
Title: Starch Binding Domain-containing Protein 1 Plays a Dominant Role in Glycogen Transport to Lysosomes in Liver.

Atg8 interacting motif (AIM) in Stbd1 is necessary for GABARAPL1 binding.
Title: Starch-binding domain-containing protein 1 (Stbd1) and glycogen metabolism: Identification of the Atg8 family interacting motif (AIM) in Stbd1 required for interaction with GABARAPL1.

The following STBD1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the STBD1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu55877	NM_003943.4 Latest version!	Homo sapiens starch binding domain 1 (STBD1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

STBD1 ( NM_003943.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003934.1 Homo sapiens starch binding domain 1 (STBD1), mRNA.

Price & Availability↑

CloneID	OHu55877
Clone ID Related Accession (Same CDS sequence)	NM_003943.4
Accession Version	NM_003943.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1077bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	starch-binding domain-containing protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK123795.1 and BC022301.1. On Jul 7, 2011 this sequence version replaced NM_003943.3. ##Evidence-Data-START## Transcript exon combination :: AK123795.1, SRR1803613.6389.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGCGCCG TCTGGTCCGC CCTGCTGGTT GGAGGGGGTC TGGCCGGAGC ACTTTTCGTT 
TGGCTGCTGC GGGGCGGCCC TGGCGACACC GGGAAGGACG GGGATGCGGA GCAGGAGAAA 
GACGCCCCTC TTGGGGGAGC TGCGATTCCG GGAGGCCATC AGAGTGGCAG CAGCGGACTG 
AGCCCTGGAC CTTCCGGGCA GGAGCTGGTC ACCAAACCAG AGCATCTTCA AGAAAGCAAT 
GGACATTTGA TTTCTAAGAC CAAAGACCTT GGTAAACTGC AAGCAGCATC ATGGAGATTG 
CAGAATCCTT CCAGGGAAGT CTGTGACAAT TCAAGAGAAC ATGTTCCTTC TGGACAGTTT 
CCAGACACAG AAGCTCCAGC TACCTCTGAG ACCAGTAACT CTAGGAGTTA CTCTGAAGTT 
TCAAGAAATG AAAGCCTTGA ATCTCCTATG GGAGAATGGG GATTCCAAAA AGGACAAGAG 
ATATCTGCTA AAGCAGCTAC ATGTTTTGCA GAGAAGTTGC CTTCTAGCAA CCTGCTCAAG 
AACAGAGCTA AAGAAGAAAT GAGCCTCTCT GATTTGAACA GTCAGGACCG GGTTGACCAC 
GAGGAGTGGG AAATGGTGCC TAGGCACTCA TCTTGGGGGG ATGTTGGTGT GGGTGGCAGT 
CTTAAGGCTC CAGTGTTAAA CCTAAACCAG GGAATGGACA ATGGAAGAAG CACTTTGGTG 
GAAGCAAGAG GTCAGCAAGT GCATGGGAAA ATGGAAAGGG TAGCAGTGAT GCCTGCAGGG 
TCTCAGCAAG TTAGTGTCAG GTTCCAGGTC CATTATGTCA CAAGCACTGA TGTGCAATTC 
ATTGCAGTAA CTGGAGACCA TGAGTGTCTT GGGAGATGGA ACACTTACAT CCCACTCCAC 
TATAACAAGG ATGGGTTCTG GTCTCATTCC ATTTTCCTGC CTGCAGATAC AGTGGTGGAG 
TGGAAGTTTG TGTTGGTAGA GAATGGGGGA GTTACCCGCT GGGAAGAATG CAGCAATAGA 
TTCCTAGAAA CTGGCCATGA GGATAAAGTG GTTCACGCAT GGTGGGGGAT TCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003934.1
CDS	745..1821
Translation	MGAVWSALLVGGGLAGALFVWLLRGGPGDTGKDGDAEQEKDAPLGGAAIPGGHQSGSSGLSPGPSGQELVTKPEHLQESNGHLISKTKDLGKLQAASWRLQNPSREVCDNSREHVPSGQFPDTEAPATSETSNSRSYSEVSRNESLESPMGEWGFQKGQEISAKAATCFAEKLPSSNLLKNRAKEEMSLSDLNSQDRVDHEEWEMVPRHSSWGDVGVGGSLKAPVLNLNQGMDNGRSTLVEARGQQVHGKMERVAVMPAGSQQVSVRFQVHYVTSTDVQFIAVTGDHECLGRWNTYIPLHYNKDGFWSHSIFLPADTVVEWKFVLVENGGVTRWEECSNRFLETGHEDKVVHAWWGIH

Target ORF information:

RefSeq Version	NM_003943.4
Organism	Homo sapiens(human)
Definition	Homo sapiens starch binding domain 1 (STBD1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003943.4

ORF Insert Sequence:

ATGGGCGCCG TCTGGTCCGC CCTGCTGGTT GGAGGGGGTC TGGCCGGAGC ACTTTTCGTT 
TGGCTGCTGC GGGGCGGCCC TGGCGACACC GGGAAGGACG GGGATGCGGA GCAGGAGAAA 
GACGCCCCTC TTGGGGGAGC TGCGATTCCG GGAGGCCATC AGAGTGGCAG CAGCGGACTG 
AGCCCTGGAC CTTCCGGGCA GGAGCTGGTC ACCAAACCAG AGCATCTTCA AGAAAGCAAT 
GGACATTTGA TTTCTAAGAC CAAAGACCTT GGTAAACTGC AAGCAGCATC ATGGAGATTG 
CAGAATCCTT CCAGGGAAGT CTGTGACAAT TCAAGAGAAC ATGTTCCTTC TGGACAGTTT 
CCAGACACAG AAGCTCCAGC TACCTCTGAG ACCAGTAACT CTAGGAGTTA CTCTGAAGTT 
TCAAGAAATG AAAGCCTTGA ATCTCCTATG GGAGAATGGG GATTCCAAAA AGGACAAGAG 
ATATCTGCTA AAGCAGCTAC ATGTTTTGCA GAGAAGTTGC CTTCTAGCAA CCTGCTCAAG 
AACAGAGCTA AAGAAGAAAT GAGCCTCTCT GATTTGAACA GTCAGGACCG GGTTGACCAC 
GAGGAGTGGG AAATGGTGCC TAGGCACTCA TCTTGGGGGG ATGTTGGTGT GGGTGGCAGT 
CTTAAGGCTC CAGTGTTAAA CCTAAACCAG GGAATGGACA ATGGAAGAAG CACTTTGGTG 
GAAGCAAGAG GTCAGCAAGT GCATGGGAAA ATGGAAAGGG TAGCAGTGAT GCCTGCAGGG 
TCTCAGCAAG TTAGTGTCAG GTTCCAGGTC CATTATGTCA CAAGCACTGA TGTGCAATTC 
ATTGCAGTAA CTGGAGACCA TGAGTGTCTT GGGAGATGGA ACACTTACAT CCCACTCCAC 
TATAACAAGG ATGGGTTCTG GTCTCATTCC ATTTTCCTGC CTGCAGATAC AGTGGTGGAG 
TGGAAGTTTG TGTTGGTAGA GAATGGGGGA GTTACCCGCT GGGAAGAATG CAGCAATAGA 
TTCCTAGAAA CTGGCCATGA GGATAAAGTG GTTCACGCAT GGTGGGGGAT TCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Starch Binding Domain-containing Protein 1 Plays a Dominant Role in Glycogen Transport to Lysosomes in Liver.
The Journal of biological chemistry291(32)16479-84(2016 08)
Sun T,Yi H,Yang C,Kishnani PS,Sun B

The carbohydrate-binding domain of overexpressed STBD1 is important for its stability and protein-protein interactions.
Bioscience reports34(4)(2014 Jul)
Zhu Y,Zhang M,Kelly AR,Cheng A

Starch-binding domain-containing protein 1 (Stbd1) and glycogen metabolism: Identification of the Atg8 family interacting motif (AIM) in Stbd1 required for interaction with GABARAPL1.
Biochemical and biophysical research communications413(3)420-5(2011 Sep)
Jiang S,Wells CD,Roach PJ

Starch binding domain-containing protein 1/genethonin 1 is a novel participant in glycogen metabolism.
The Journal of biological chemistry285(45)34960-71(2010 Nov)
Jiang S,Heller B,Tagliabracci VS,Zhai L,Irimia JM,DePaoli-Roach AA,Wells CD,Skurat AV,Roach PJ

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STBD1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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