TNFRSF6B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TNFRSF6B
Entrez Gene ID	8771
Full Name	TNF receptor superfamily member 6b
Synonyms	DCR3,DJ583P15.1.1,M68,M68E,TR6
General protein information	Preferred Names TNF receptor superfamily member 6b Names tumor necrosis factor receptor superfamily member 6B decoy receptor 3 variant 1 decoy receptor 3 variant 2 decoy receptor for Fas ligand tumor necrosis factor receptor superfamily, member 6b, decoy
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20q13.33
Summary	This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript. [provided by RefSeq, Feb 2011].
Disorder MIM:	603361

mRNA and Protein(s)

mRNA	Protein	Name
NM_003823.3	NP_003814.1	tumor necrosis factor receptor superfamily member 6B precursor
NM_003823.4	NP_003814.1	tumor necrosis factor receptor superfamily member 6B precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	TNFRSF6B	NP_001094776.1
Homo sapiens (human)	TNFRSF6B	NP_003814.1
Canis lupus familiaris (dog)	TNFRSF6B	XP_005635353.1
	LOC100426722	XP_002798109.1
Gallus gallus (chicken)	TNFRSF6B	XP_417434.2

Gene Ontology

The following TNFRSF6B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TNFRSF6B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu15887	NM_003823.4 Latest version!	Homo sapiens TNF receptor superfamily member 6b (TNFRSF6B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$216.30 $309.00
View Old Accession Versions >>
OHu15887	NM_003823.3	Homo sapiens TNF receptor superfamily member 6b (TNFRSF6B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$216.30 $309.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TNFRSF6B ( NM_003823.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003814.1 Homo sapiens TNF receptor superfamily member 6b (TNFRSF6B), mRNA.

Price & Availability↑

CloneID	OHu15887
Clone ID Related Accession (Same CDS sequence)	NM_003823.3 , NM_003823.4
Accession Version	NM_003823.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 903bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-01
Organism	Homo sapiens(human)
Product	tumor necrosis factor receptor superfamily member 6B precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM759033.1, BC034349.1, AW204999.1 and AL121845.20. This sequence is a reference standard in the RefSeqGene project. On Feb 18, 2011 this sequence version replaced NM_003823.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.398972.1, AF104419.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGAGGGCGC TGGAGGGGCC AGGCCTGTCG CTGCTGTGCC TGGTGTTGGC GCTGCCTGCC 
CTGCTGCCGG TGCCGGCTGT ACGCGGAGTG GCAGAAACAC CCACCTACCC CTGGCGGGAC 
GCAGAGACAG GGGAGCGGCT GGTGTGCGCC CAGTGCCCCC CAGGCACCTT TGTGCAGCGG 
CCGTGCCGCC GAGACAGCCC CACGACGTGT GGCCCGTGTC CACCGCGCCA CTACACGCAG 
TTCTGGAACT ACCTAGAGCG CTGCCGCTAC TGCAACGTCC TCTGCGGGGA GCGTGAGGAG 
GAGGCACGGG CTTGCCACGC CACCCACAAC CGTGCCTGCC GCTGCCGCAC CGGCTTCTTC 
GCGCACGCTG GTTTCTGCTT GGAGCACGCA TCGTGTCCAC CTGGTGCCGG CGTGATTGCC 
CCGGGCACCC CCAGCCAGAA CACGCAGTGC CAGCCGTGCC CCCCAGGCAC CTTCTCAGCC 
AGCAGCTCCA GCTCAGAGCA GTGCCAGCCC CACCGCAACT GCACGGCCCT GGGCCTGGCC 
CTCAATGTGC CAGGCTCTTC CTCCCATGAC ACCCTGTGCA CCAGCTGCAC TGGCTTCCCC 
CTCAGCACCA GGGTACCAGG AGCTGAGGAG TGTGAGCGTG CCGTCATCGA CTTTGTGGCT 
TTCCAGGACA TCTCCATCAA GAGGCTGCAG CGGCTGCTGC AGGCCCTCGA GGCCCCGGAG 
GGCTGGGGTC CGACACCAAG GGCGGGCCGC GCGGCCTTGC AGCTGAAGCT GCGTCGGCGG 
CTCACGGAGC TCCTGGGGGC GCAGGACGGG GCGCTGCTGG TGCGGCTGCT GCAGGCGCTG 
CGCGTGGCCA GGATGCCCGG GCTGGAGCGG AGCGTCCGTG AGCGCTTCCT CCCTGTGCAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003814.1
CDS	118..1020
Translation	MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISIKRLQRLLQALEAPEGWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMPGLERSVRERFLPVH

Target ORF information:

RefSeq Version	NM_003823.3
Organism	Homo sapiens(human)
Definition	Homo sapiens TNF receptor superfamily member 6b (TNFRSF6B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003823.3

ORF Insert Sequence:

ATGAGGGCGC TGGAGGGGCC AGGCCTGTCG CTGCTGTGCC TGGTGTTGGC GCTGCCTGCC 
CTGCTGCCGG TGCCGGCTGT ACGCGGAGTG GCAGAAACAC CCACCTACCC CTGGCGGGAC 
GCAGAGACAG GGGAGCGGCT GGTGTGCGCC CAGTGCCCCC CAGGCACCTT TGTGCAGCGG 
CCGTGCCGCC GAGACAGCCC CACGACGTGT GGCCCGTGTC CACCGCGCCA CTACACGCAG 
TTCTGGAACT ACCTAGAGCG CTGCCGCTAC TGCAACGTCC TCTGCGGGGA GCGTGAGGAG 
GAGGCACGGG CTTGCCACGC CACCCACAAC CGTGCCTGCC GCTGCCGCAC CGGCTTCTTC 
GCGCACGCTG GTTTCTGCTT GGAGCACGCA TCGTGTCCAC CTGGTGCCGG CGTGATTGCC 
CCGGGCACCC CCAGCCAGAA CACGCAGTGC CAGCCGTGCC CCCCAGGCAC CTTCTCAGCC 
AGCAGCTCCA GCTCAGAGCA GTGCCAGCCC CACCGCAACT GCACGGCCCT GGGCCTGGCC 
CTCAATGTGC CAGGCTCTTC CTCCCATGAC ACCCTGTGCA CCAGCTGCAC TGGCTTCCCC 
CTCAGCACCA GGGTACCAGG AGCTGAGGAG TGTGAGCGTG CCGTCATCGA CTTTGTGGCT 
TTCCAGGACA TCTCCATCAA GAGGCTGCAG CGGCTGCTGC AGGCCCTCGA GGCCCCGGAG 
GGCTGGGGTC CGACACCAAG GGCGGGCCGC GCGGCCTTGC AGCTGAAGCT GCGTCGGCGG 
CTCACGGAGC TCCTGGGGGC GCAGGACGGG GCGCTGCTGG TGCGGCTGCT GCAGGCGCTG 
CGCGTGGCCA GGATGCCCGG GCTGGAGCGG AGCGTCCGTG AGCGCTTCCT CCCTGTGCAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TNFRSF6B ( NM_003823.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003814.1 Homo sapiens TNF receptor superfamily member 6b (TNFRSF6B), mRNA.

Price & Availability↑

CloneID	OHu15887
Clone ID Related Accession (Same CDS sequence)	NM_003823.3 , NM_003823.4
Accession Version	NM_003823.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 903bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Homo sapiens(human)
Product	tumor necrosis factor receptor superfamily member 6B precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM759033.1, BC034349.1 and AW204999.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_003823.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.398972.1, AF104419.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000369996.3/ ENSP00000359013.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGGGCGC TGGAGGGGCC AGGCCTGTCG CTGCTGTGCC TGGTGTTGGC GCTGCCTGCC 
CTGCTGCCGG TGCCGGCTGT ACGCGGAGTG GCAGAAACAC CCACCTACCC CTGGCGGGAC 
GCAGAGACAG GGGAGCGGCT GGTGTGCGCC CAGTGCCCCC CAGGCACCTT TGTGCAGCGG 
CCGTGCCGCC GAGACAGCCC CACGACGTGT GGCCCGTGTC CACCGCGCCA CTACACGCAG 
TTCTGGAACT ACCTAGAGCG CTGCCGCTAC TGCAACGTCC TCTGCGGGGA GCGTGAGGAG 
GAGGCACGGG CTTGCCACGC CACCCACAAC CGTGCCTGCC GCTGCCGCAC CGGCTTCTTC 
GCGCACGCTG GTTTCTGCTT GGAGCACGCA TCGTGTCCAC CTGGTGCCGG CGTGATTGCC 
CCGGGCACCC CCAGCCAGAA CACGCAGTGC CAGCCGTGCC CCCCAGGCAC CTTCTCAGCC 
AGCAGCTCCA GCTCAGAGCA GTGCCAGCCC CACCGCAACT GCACGGCCCT GGGCCTGGCC 
CTCAATGTGC CAGGCTCTTC CTCCCATGAC ACCCTGTGCA CCAGCTGCAC TGGCTTCCCC 
CTCAGCACCA GGGTACCAGG AGCTGAGGAG TGTGAGCGTG CCGTCATCGA CTTTGTGGCT 
TTCCAGGACA TCTCCATCAA GAGGCTGCAG CGGCTGCTGC AGGCCCTCGA GGCCCCGGAG 
GGCTGGGGTC CGACACCAAG GGCGGGCCGC GCGGCCTTGC AGCTGAAGCT GCGTCGGCGG 
CTCACGGAGC TCCTGGGGGC GCAGGACGGG GCGCTGCTGG TGCGGCTGCT GCAGGCGCTG 
CGCGTGGCCA GGATGCCCGG GCTGGAGCGG AGCGTCCGTG AGCGCTTCCT CCCTGTGCAC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003814.1
CDS	117..1019
Translation	MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISIKRLQRLLQALEAPEGWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMPGLERSVRERFLPVH

Target ORF information:

RefSeq Version	NM_003823.4
Organism	Homo sapiens(human)
Definition	Homo sapiens TNF receptor superfamily member 6b (TNFRSF6B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003823.4

ORF Insert Sequence:

ATGAGGGCGC TGGAGGGGCC AGGCCTGTCG CTGCTGTGCC TGGTGTTGGC GCTGCCTGCC 
CTGCTGCCGG TGCCGGCTGT ACGCGGAGTG GCAGAAACAC CCACCTACCC CTGGCGGGAC 
GCAGAGACAG GGGAGCGGCT GGTGTGCGCC CAGTGCCCCC CAGGCACCTT TGTGCAGCGG 
CCGTGCCGCC GAGACAGCCC CACGACGTGT GGCCCGTGTC CACCGCGCCA CTACACGCAG 
TTCTGGAACT ACCTAGAGCG CTGCCGCTAC TGCAACGTCC TCTGCGGGGA GCGTGAGGAG 
GAGGCACGGG CTTGCCACGC CACCCACAAC CGTGCCTGCC GCTGCCGCAC CGGCTTCTTC 
GCGCACGCTG GTTTCTGCTT GGAGCACGCA TCGTGTCCAC CTGGTGCCGG CGTGATTGCC 
CCGGGCACCC CCAGCCAGAA CACGCAGTGC CAGCCGTGCC CCCCAGGCAC CTTCTCAGCC 
AGCAGCTCCA GCTCAGAGCA GTGCCAGCCC CACCGCAACT GCACGGCCCT GGGCCTGGCC 
CTCAATGTGC CAGGCTCTTC CTCCCATGAC ACCCTGTGCA CCAGCTGCAC TGGCTTCCCC 
CTCAGCACCA GGGTACCAGG AGCTGAGGAG TGTGAGCGTG CCGTCATCGA CTTTGTGGCT 
TTCCAGGACA TCTCCATCAA GAGGCTGCAG CGGCTGCTGC AGGCCCTCGA GGCCCCGGAG 
GGCTGGGGTC CGACACCAAG GGCGGGCCGC GCGGCCTTGC AGCTGAAGCT GCGTCGGCGG 
CTCACGGAGC TCCTGGGGGC GCAGGACGGG GCGCTGCTGG TGCGGCTGCT GCAGGCGCTG 
CGCGTGGCCA GGATGCCCGG GCTGGAGCGG AGCGTCCGTG AGCGCTTCCT CCCTGTGCAC 
TGA