RAX2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RAX2
Entrez Gene ID	84839
Full Name	retina and anterior neural fold homeobox 2
Synonyms	ARMD6,CORD11,QRX,RAXL1
General protein information	Preferred Names retina and anterior neural fold homeobox 2 Names retina and anterior neural fold homeobox protein 2 Q50-type retinal homeobox protein retina and anterior neural fold homeobox like 1 retina and anterior neural fold homeobox-like protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19p13.3
Summary	This gene encodes a homeodomain-containing protein that plays a role in eye development. Mutation of this gene causes age-related macular degeneration type 6, an eye disorder resulting in accumulations of protein and lipid beneath the retinal pigment epithelium and within the Bruch's membrane. Defects in this gene can also cause cone-rod dystrophy type 11, a disease characterized by the initial degeneration of cone photoreceptor cells and resulting in loss of color vision and visual acuity, followed by the degeneration of rod photoreceptor cells, which progresses to night blindness and the loss of peripheral vision. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016].
Disorder MIM:	610362
Disorder Html:	?Macular degeneration, age-related, 6, 613757 (3); Cone-rod dystrophy 11, 610381 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001319074.2	NP_001306003.1	retina and anterior neural fold homeobox protein 2 isoform 1
NM_001319074.1	NP_001306003.1	retina and anterior neural fold homeobox protein 2 isoform 1
NM_032753.4	NP_116142.1	retina and anterior neural fold homeobox protein 2
NM_001319074.4	NP_001306003.2	retina and anterior neural fold homeobox protein 2
NM_032753.3	NP_116142.1	retina and anterior neural fold homeobox protein 2 isoform 2

Pathways from BioSystems

Homologies

	RAX2	XP_002801073.1
Canis lupus familiaris (dog)	RAX2	XP_005633128.1
Bos taurus (cattle)	RAX2	NP_872594.1
Homo sapiens (human)	RAX2	NP_116142.1
Pan troglodytes (chimpanzee)	RAX2	NP_001074956.1

Gene Ontology
Bibliography

Related articles in PubMed

Autosomal Dominant Retinal Dystrophy With Electronegative Waveform Associated With a Novel RAX2 Mutation.
Yang P, Chiang PW, Weleber RG, Pennesi ME
JAMA ophthalmology133(6)653-61(2015 Jun)

New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
Genes and immunity11(3)232-8(2010 Apr)

A census of human transcription factors: function, expression and evolution.
Vaquerizas JM, Kummerfeld SK, Teichmann SA, Luscombe NM
Nature reviews. Genetics10(4)252-63(2009 04)

QRX, a novel homeobox gene, modulates photoreceptor gene expression.
Wang QL, Chen S, Esumi N, Swain PK, Haines HS, Peng G, Melia BM, McIntosh I, Heckenlively JR, Jacobson SG, Stone EM, Swaroop A, Zack DJ
Human molecular genetics13(10)1025-40(2004 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

A frameshift heterozygous mutation in RAX2 inherited in an autosomal dominant fashion was associated with mixed cone and rod dysfunction.
Title: Autosomal Dominant Retinal Dystrophy With Electronegative Waveform Associated With a Novel RAX2 Mutation.

Observational study of gene-disease association. (HuGE Navigator)
Title: New genetic associations detected in a host response study to hepatitis B vaccine.

The following RAX2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RAX2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19084	NM_032753.4 Latest version!	Homo sapiens retina and anterior neural fold homeobox 2 (RAX2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu19084	NM_001319074.4 Latest version!	Homo sapiens retina and anterior neural fold homeobox 2 (RAX2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu51871	NM_001319074.2 Latest version!	Homo sapiens retina and anterior neural fold homeobox 2 (RAX2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
View Old Accession Versions >>
OHu51871	NM_001319074.1	Homo sapiens retina and anterior neural fold homeobox 2 (RAX2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
OHu19084	NM_032753.3	Homo sapiens retina and anterior neural fold homeobox 2 (RAX2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RAX2 ( NM_032753.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_116142.1 Homo sapiens retina and anterior neural fold homeobox 2 (RAX2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu19084
Clone ID Related Accession (Same CDS sequence)	NM_032753.4 , NM_001319074.4 , NM_032753.3
Accession Version	NM_032753.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 555bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Homo sapiens(human)
Product	retina and anterior neural fold homeobox protein 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC005777.1, BC018709.1 and AY211277.1. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2019 this sequence version replaced NM_032753.3. ##Evidence-Data-START## Transcript exon combination :: AY211277.1, BQ639073.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN01820699 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTCCTGA GCCCGGGCGA GGGGCCGGCA ACCGAGGGTG GGGGTCTGGG GCCGGGCGAG 
GAGGCCCCCA AGAAGAAGCA CCGGAGGAAC CGCACCACCT TCACCACCTA CCAGCTGCAC 
CAGCTGGAGC GGGCGTTCGA GGCCTCTCAC TACCCGGATG TGTACAGCCG TGAGGAGCTG 
GCAGCCAAGG TGCACCTACC TGAGGTGCGC GTGCAGGTGT GGTTCCAGAA CCGCCGGGCC 
AAGTGGCGCC GCCAGGAGCG GCTGGAGTCA GGCTCGGGTG CCGTGGCAGC TCCGAGACTC 
CCCGAGGCCC CAGCGCTGCC GTTCGCCCGC CCCCCGGCCA TGTCGCTGCC CCTGGAGCCC 
TGGTTGGGCC CCGGACCGCC GGCCGTGCCA GGCCTCCCCC GCCTCCTGGG CCCGGGCCCG 
GGGCTGCAAG CGTCCTTCGG GCCTCATGCC TTTGCTCCCA CCTTCGCAGA TGGCTTCGCC 
CTGGAGGAGG CGTCCCTGCG GCTGCTGGCC AAGGAACATG CACAGGCTCT GGACAGGGCC 
TGGCCGCCAG CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_116142.1
CDS	76..630
Translation	MFLSPGEGPATEGGGLGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWRRQERLESGSGAVAAPRLPEAPALPFARPPAMSLPLEPWLGPGPPAVPGLPRLLGPGPGLQASFGPHAFAPTFADGFALEEASLRLLAKEHAQALDRAWPPA

Target ORF information:

RefSeq Version	NM_032753.4
Organism	Homo sapiens(human)
Definition	Homo sapiens retina and anterior neural fold homeobox 2 (RAX2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032753.4

ORF Insert Sequence:

ATGTTCCTGA GCCCGGGCGA GGGGCCGGCA ACCGAGGGTG GGGGTCTGGG GCCGGGCGAG 
GAGGCCCCCA AGAAGAAGCA CCGGAGGAAC CGCACCACCT TCACCACCTA CCAGCTGCAC 
CAGCTGGAGC GGGCGTTCGA GGCCTCTCAC TACCCGGATG TGTACAGCCG TGAGGAGCTG 
GCAGCCAAGG TGCACCTACC TGAGGTGCGC GTGCAGGTGT GGTTCCAGAA CCGCCGGGCC 
AAGTGGCGCC GCCAGGAGCG GCTGGAGTCA GGCTCGGGTG CCGTGGCAGC TCCGAGACTC 
CCCGAGGCCC CAGCGCTGCC GTTCGCCCGC CCCCCGGCCA TGTCGCTGCC CCTGGAGCCC 
TGGTTGGGCC CCGGACCGCC GGCCGTGCCA GGCCTCCCCC GCCTCCTGGG CCCGGGCCCG 
GGGCTGCAAG CGTCCTTCGG GCCTCATGCC TTTGCTCCCA CCTTCGCAGA TGGCTTCGCC 
CTGGAGGAGG CGTCCCTGCG GCTGCTGGCC AAGGAACATG CACAGGCTCT GGACAGGGCC 
TGGCCGCCAG CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAX2 ( NM_001319074.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001306003.2 Homo sapiens retina and anterior neural fold homeobox 2 (RAX2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu19084
Clone ID Related Accession (Same CDS sequence)	NM_032753.4 , NM_001319074.4 , NM_032753.3
Accession Version	NM_001319074.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 555bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-29
Organism	Homo sapiens(human)
Product	retina and anterior neural fold homeobox protein 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC005777.1. On Oct 30, 2019 this sequence version replaced NM_001319074.3. Sequence Note:. ##Evidence-Data-START## Transcript exon combination :: BC032512.1, BM083893.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTTCCTGA GCCCGGGCGA GGGGCCGGCA ACCGAGGGTG GGGGTCTGGG GCCGGGCGAG 
GAGGCCCCCA AGAAGAAGCA CCGGAGGAAC CGCACCACCT TCACCACCTA CCAGCTGCAC 
CAGCTGGAGC GGGCGTTCGA GGCCTCTCAC TACCCGGATG TGTACAGCCG TGAGGAGCTG 
GCAGCCAAGG TGCACCTACC TGAGGTGCGC GTGCAGGTGT GGTTCCAGAA CCGCCGGGCC 
AAGTGGCGCC GCCAGGAGCG GCTGGAGTCA GGCTCGGGTG CCGTGGCAGC TCCGAGACTC 
CCCGAGGCCC CAGCGCTGCC GTTCGCCCGC CCCCCGGCCA TGTCGCTGCC CCTGGAGCCC 
TGGTTGGGCC CCGGACCGCC GGCCGTGCCA GGCCTCCCCC GCCTCCTGGG CCCGGGCCCG 
GGGCTGCAAG CGTCCTTCGG GCCTCATGCC TTTGCTCCCA CCTTCGCAGA TGGCTTCGCC 
CTGGAGGAGG CGTCCCTGCG GCTGCTGGCC AAGGAACATG CACAGGCTCT GGACAGGGCC 
TGGCCGCCAG CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001306003.2
CDS	335..889
Translation	MFLSPGEGPATEGGGLGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWRRQERLESGSGAVAAPRLPEAPALPFARPPAMSLPLEPWLGPGPPAVPGLPRLLGPGPGLQASFGPHAFAPTFADGFALEEASLRLLAKEHAQALDRAWPPA

Target ORF information:

RefSeq Version	NM_001319074.4
Organism	Homo sapiens(human)
Definition	Homo sapiens retina and anterior neural fold homeobox 2 (RAX2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001319074.4

ORF Insert Sequence:

ATGTTCCTGA GCCCGGGCGA GGGGCCGGCA ACCGAGGGTG GGGGTCTGGG GCCGGGCGAG 
GAGGCCCCCA AGAAGAAGCA CCGGAGGAAC CGCACCACCT TCACCACCTA CCAGCTGCAC 
CAGCTGGAGC GGGCGTTCGA GGCCTCTCAC TACCCGGATG TGTACAGCCG TGAGGAGCTG 
GCAGCCAAGG TGCACCTACC TGAGGTGCGC GTGCAGGTGT GGTTCCAGAA CCGCCGGGCC 
AAGTGGCGCC GCCAGGAGCG GCTGGAGTCA GGCTCGGGTG CCGTGGCAGC TCCGAGACTC 
CCCGAGGCCC CAGCGCTGCC GTTCGCCCGC CCCCCGGCCA TGTCGCTGCC CCTGGAGCCC 
TGGTTGGGCC CCGGACCGCC GGCCGTGCCA GGCCTCCCCC GCCTCCTGGG CCCGGGCCCG 
GGGCTGCAAG CGTCCTTCGG GCCTCATGCC TTTGCTCCCA CCTTCGCAGA TGGCTTCGCC 
CTGGAGGAGG CGTCCCTGCG GCTGCTGGCC AAGGAACATG CACAGGCTCT GGACAGGGCC 
TGGCCGCCAG CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAX2 ( NM_032753.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_116142.1 Homo sapiens retina and anterior neural fold homeobox 2 (RAX2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu19084
Clone ID Related Accession (Same CDS sequence)	NM_032753.4 , NM_001319074.4 , NM_032753.3
Accession Version	NM_032753.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 555bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	retina and anterior neural fold homeobox protein 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC018709.1 and AY211277.1. This sequence is a reference standard in the RefSeqGene project. On Jan 11, 2008 this sequence version replaced NM_032753.2. Transcript Variant: This variant (2) uses an alternate splice site the the 5' coding region, which results in the use of a downstream in-frame start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus than isoform 1. ##Evidence-Data-START## Transcript exon combination :: AY211277.1, BQ639073.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN01820699 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTCCTGA GCCCGGGCGA GGGGCCGGCA ACCGAGGGTG GGGGTCTGGG GCCGGGCGAG 
GAGGCCCCCA AGAAGAAGCA CCGGAGGAAC CGCACCACCT TCACCACCTA CCAGCTGCAC 
CAGCTGGAGC GGGCGTTCGA GGCCTCTCAC TACCCGGATG TGTACAGCCG TGAGGAGCTG 
GCAGCCAAGG TGCACCTACC TGAGGTGCGC GTGCAGGTGT GGTTCCAGAA CCGCCGGGCC 
AAGTGGCGCC GCCAGGAGCG GCTGGAGTCA GGCTCGGGTG CCGTGGCAGC TCCGAGACTC 
CCCGAGGCCC CAGCGCTGCC GTTCGCCCGC CCCCCGGCCA TGTCGCTGCC CCTGGAGCCC 
TGGTTGGGCC CCGGACCGCC GGCCGTGCCA GGCCTCCCCC GCCTCCTGGG CCCGGGCCCG 
GGGCTGCAAG CGTCCTTCGG GCCTCATGCC TTTGCTCCCA CCTTCGCAGA TGGCTTCGCC 
CTGGAGGAGG CGTCCCTGCG GCTGCTGGCC AAGGAACATG CACAGGCTCT GGACAGGGCC 
TGGCCGCCAG CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_116142.1
CDS	69..623
Translation	MFLSPGEGPATEGGGLGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWRRQERLESGSGAVAAPRLPEAPALPFARPPAMSLPLEPWLGPGPPAVPGLPRLLGPGPGLQASFGPHAFAPTFADGFALEEASLRLLAKEHAQALDRAWPPA

Target ORF information:

RefSeq Version	NM_032753.3
Organism	Homo sapiens(human)
Definition	Homo sapiens retina and anterior neural fold homeobox 2 (RAX2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032753.3

ORF Insert Sequence:

ATGTTCCTGA GCCCGGGCGA GGGGCCGGCA ACCGAGGGTG GGGGTCTGGG GCCGGGCGAG 
GAGGCCCCCA AGAAGAAGCA CCGGAGGAAC CGCACCACCT TCACCACCTA CCAGCTGCAC 
CAGCTGGAGC GGGCGTTCGA GGCCTCTCAC TACCCGGATG TGTACAGCCG TGAGGAGCTG 
GCAGCCAAGG TGCACCTACC TGAGGTGCGC GTGCAGGTGT GGTTCCAGAA CCGCCGGGCC 
AAGTGGCGCC GCCAGGAGCG GCTGGAGTCA GGCTCGGGTG CCGTGGCAGC TCCGAGACTC 
CCCGAGGCCC CAGCGCTGCC GTTCGCCCGC CCCCCGGCCA TGTCGCTGCC CCTGGAGCCC 
TGGTTGGGCC CCGGACCGCC GGCCGTGCCA GGCCTCCCCC GCCTCCTGGG CCCGGGCCCG 
GGGCTGCAAG CGTCCTTCGG GCCTCATGCC TTTGCTCCCA CCTTCGCAGA TGGCTTCGCC 
CTGGAGGAGG CGTCCCTGCG GCTGCTGGCC AAGGAACATG CACAGGCTCT GGACAGGGCC 
TGGCCGCCAG CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAX2 ( NM_001319074.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001306003.1 Homo sapiens retina and anterior neural fold homeobox 2 (RAX2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu51871
Clone ID Related Accession (Same CDS sequence)	NM_001319074.2 , NM_001319074.1
Accession Version	NM_001319074.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 693bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-01
Organism	Homo sapiens(human)
Product	retina and anterior neural fold homeobox protein 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC005777.1, BC018709.1 and BC007284.1. On Jun 2, 2019 this sequence version replaced NM_001319074.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: BC032512.1, BM083893.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN01820699, SAMN03465421 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCGGCCC CAGTGGAGGG AACCGATTTC CCCGGAGCCG GGAGGCAAGC CTGGGGCTCC 
CCTGCCCTGT CCCTGCCGGT AGCCCCCCCA GCCGTCTCCC CACCATCTGT CCCGCTGCCG 
TCCCACCAGG TGGGAGCCAT GTTCCTGAGC CCGGGCGAGG GGCCGGCAAC CGAGGGTGGG 
GGTCTGGGGC CGGGCGAGGA GGCCCCCAAG AAGAAGCACC GGAGGAACCG CACCACCTTC 
ACCACCTACC AGCTGCACCA GCTGGAGCGG GCGTTCGAGG CCTCTCACTA CCCGGATGTG 
TACAGCCGTG AGGAGCTGGC AGCCAAGGTG CACCTACCTG AGGTGCGCGT GCAGGTGTGG 
TTCCAGAACC GCCGGGCCAA GTGGCGCCGC CAGGAGCGGC TGGAGTCAGG CTCGGGTGCC 
GTGGCAGCTC CGAGACTCCC CGAGGCCCCA GCGCTGCCGT TCGCCCGCCC CCCGGCCATG 
TCGCTGCCCC TGGAGCCCTG GTTGGGCCCC GGACCGCCGG CCGTGCCAGG CCTCCCCCGC 
CTCCTGGGCC CGGGCCCGGG GCTGCAAGCG TCCTTCGGGC CTCATGCCTT TGCTCCCACC 
TTCGCAGATG GCTTCGCCCT GGAGGAGGCG TCCCTGCGGC TGCTGGCCAA GGAACATGCA 
CAGGCTCTGG ACAGGGCCTG GCCGCCAGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001306003.1
CDS	197..889
Translation	MPAPVEGTDFPGAGRQAWGSPALSLPVAPPAVSPPSVPLPSHQVGAMFLSPGEGPATEGGGLGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWRRQERLESGSGAVAAPRLPEAPALPFARPPAMSLPLEPWLGPGPPAVPGLPRLLGPGPGLQASFGPHAFAPTFADGFALEEASLRLLAKEHAQALDRAWPPA

Target ORF information:

RefSeq Version	NM_001319074.2
Organism	Homo sapiens(human)
Definition	Homo sapiens retina and anterior neural fold homeobox 2 (RAX2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001319074.2

ORF Insert Sequence:

ATGCCGGCCC CAGTGGAGGG AACCGATTTC CCCGGAGCCG GGAGGCAAGC CTGGGGCTCC 
CCTGCCCTGT CCCTGCCGGT AGCCCCCCCA GCCGTCTCCC CACCATCTGT CCCGCTGCCG 
TCCCACCAGG TGGGAGCCAT GTTCCTGAGC CCGGGCGAGG GGCCGGCAAC CGAGGGTGGG 
GGTCTGGGGC CGGGCGAGGA GGCCCCCAAG AAGAAGCACC GGAGGAACCG CACCACCTTC 
ACCACCTACC AGCTGCACCA GCTGGAGCGG GCGTTCGAGG CCTCTCACTA CCCGGATGTG 
TACAGCCGTG AGGAGCTGGC AGCCAAGGTG CACCTACCTG AGGTGCGCGT GCAGGTGTGG 
TTCCAGAACC GCCGGGCCAA GTGGCGCCGC CAGGAGCGGC TGGAGTCAGG CTCGGGTGCC 
GTGGCAGCTC CGAGACTCCC CGAGGCCCCA GCGCTGCCGT TCGCCCGCCC CCCGGCCATG 
TCGCTGCCCC TGGAGCCCTG GTTGGGCCCC GGACCGCCGG CCGTGCCAGG CCTCCCCCGC 
CTCCTGGGCC CGGGCCCGGG GCTGCAAGCG TCCTTCGGGC CTCATGCCTT TGCTCCCACC 
TTCGCAGATG GCTTCGCCCT GGAGGAGGCG TCCCTGCGGC TGCTGGCCAA GGAACATGCA 
CAGGCTCTGG ACAGGGCCTG GCCGCCAGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAX2 ( NM_001319074.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001306003.1 Homo sapiens retina and anterior neural fold homeobox 2 (RAX2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu51871
Clone ID Related Accession (Same CDS sequence)	NM_001319074.2 , NM_001319074.1
Accession Version	NM_001319074.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 693bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-30
Organism	Homo sapiens(human)
Product	retina and anterior neural fold homeobox protein 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC018709.1, AC005777.1 and BC007284.1. On Jan 22, 2016 this sequence version replaced XM_005259662.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: BC018709.1, BC007284.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN01820699, SAMN03465421 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCGGCCC CAGTGGAGGG AACCGATTTC CCCGGAGCCG GGAGGCAAGC CTGGGGCTCC 
CCTGCCCTGT CCCTGCCGGT AGCCCCCCCA GCCGTCTCCC CACCATCTGT CCCGCTGCCG 
TCCCACCAGG TGGGAGCCAT GTTCCTGAGC CCGGGCGAGG GGCCGGCAAC CGAGGGTGGG 
GGTCTGGGGC CGGGCGAGGA GGCCCCCAAG AAGAAGCACC GGAGGAACCG CACCACCTTC 
ACCACCTACC AGCTGCACCA GCTGGAGCGG GCGTTCGAGG CCTCTCACTA CCCGGATGTG 
TACAGCCGTG AGGAGCTGGC AGCCAAGGTG CACCTACCTG AGGTGCGCGT GCAGGTGTGG 
TTCCAGAACC GCCGGGCCAA GTGGCGCCGC CAGGAGCGGC TGGAGTCAGG CTCGGGTGCC 
GTGGCAGCTC CGAGACTCCC CGAGGCCCCA GCGCTGCCGT TCGCCCGCCC CCCGGCCATG 
TCGCTGCCCC TGGAGCCCTG GTTGGGCCCC GGACCGCCGG CCGTGCCAGG CCTCCCCCGC 
CTCCTGGGCC CGGGCCCGGG GCTGCAAGCG TCCTTCGGGC CTCATGCCTT TGCTCCCACC 
TTCGCAGATG GCTTCGCCCT GGAGGAGGCG TCCCTGCGGC TGCTGGCCAA GGAACATGCA 
CAGGCTCTGG ACAGGGCCTG GCCGCCAGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001306003.1
CDS	190..882
Translation	MPAPVEGTDFPGAGRQAWGSPALSLPVAPPAVSPPSVPLPSHQVGAMFLSPGEGPATEGGGLGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWRRQERLESGSGAVAAPRLPEAPALPFARPPAMSLPLEPWLGPGPPAVPGLPRLLGPGPGLQASFGPHAFAPTFADGFALEEASLRLLAKEHAQALDRAWPPA

Target ORF information:

RefSeq Version	NM_001319074.1
Organism	Homo sapiens(human)
Definition	Homo sapiens retina and anterior neural fold homeobox 2 (RAX2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001319074.1

ORF Insert Sequence:

ATGCCGGCCC CAGTGGAGGG AACCGATTTC CCCGGAGCCG GGAGGCAAGC CTGGGGCTCC 
CCTGCCCTGT CCCTGCCGGT AGCCCCCCCA GCCGTCTCCC CACCATCTGT CCCGCTGCCG 
TCCCACCAGG TGGGAGCCAT GTTCCTGAGC CCGGGCGAGG GGCCGGCAAC CGAGGGTGGG 
GGTCTGGGGC CGGGCGAGGA GGCCCCCAAG AAGAAGCACC GGAGGAACCG CACCACCTTC 
ACCACCTACC AGCTGCACCA GCTGGAGCGG GCGTTCGAGG CCTCTCACTA CCCGGATGTG 
TACAGCCGTG AGGAGCTGGC AGCCAAGGTG CACCTACCTG AGGTGCGCGT GCAGGTGTGG 
TTCCAGAACC GCCGGGCCAA GTGGCGCCGC CAGGAGCGGC TGGAGTCAGG CTCGGGTGCC 
GTGGCAGCTC CGAGACTCCC CGAGGCCCCA GCGCTGCCGT TCGCCCGCCC CCCGGCCATG 
TCGCTGCCCC TGGAGCCCTG GTTGGGCCCC GGACCGCCGG CCGTGCCAGG CCTCCCCCGC 
CTCCTGGGCC CGGGCCCGGG GCTGCAAGCG TCCTTCGGGC CTCATGCCTT TGCTCCCACC 
TTCGCAGATG GCTTCGCCCT GGAGGAGGCG TCCCTGCGGC TGCTGGCCAA GGAACATGCA 
CAGGCTCTGG ACAGGGCCTG GCCGCCAGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Autosomal Dominant Retinal Dystrophy With Electronegative Waveform Associated With a Novel RAX2 Mutation.
JAMA ophthalmology133(6)653-61(2015 Jun)
Yang P,Chiang PW,Weleber RG,Pennesi ME

New genetic associations detected in a host response study to hepatitis B vaccine.
Genes and immunity11(3)232-8(2010 Apr)
Davila S,Froeling FE,Tan A,Bonnard C,Boland GJ,Snippe H,Hibberd ML,Seielstad M

A census of human transcription factors: function, expression and evolution.
Nature reviews. Genetics10(4)252-63(2009 04)
Vaquerizas JM,Kummerfeld SK,Teichmann SA,Luscombe NM

QRX, a novel homeobox gene, modulates photoreceptor gene expression.
Human molecular genetics13(10)1025-40(2004 May)
Wang QL,Chen S,Esumi N,Swain PK,Haines HS,Peng G,Melia BM,McIntosh I,Heckenlively JR,Jacobson SG,Stone EM,Swaroop A,Zack DJ

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RAX2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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