TAAR8 cDNA ORF clone, Homo sapiens(Human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TAAR8
Entrez Gene ID	83551
Full Name	trace amine associated receptor 8
Synonyms	GPR102,TA5,TAR5,TRAR5,TaR-5,TaR-8
General protein information	Preferred Names trace amine associated receptor 8 Names trace amine-associated receptor 8 G-protein coupled receptor 102 trace amine receptor 5 trace amine receptor 8
Gene Type	protein-coding
Organism	Homo sapiens(Human)
Genome	Chromosome: 6 Map Location: 6q23.2
Summary	This gene is part of the trace amine receptor cluster on chromosome 6 and encodes an orphan G-protein coupled receptor. Upregulated expression of this gene in astroglial cells upon exposure to lipopolysaccharides suggests a function for the encoded protein in the brain. [provided by RefSeq, Jul 2016].
Disorder MIM:	606927

mRNA and Protein(s)

mRNA	Protein	Name
NM_053278.2	NP_444508.1	trace amine-associated receptor 8
NM_053278.1	NP_444508.1	trace amine-associated receptor 8

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Taar8a	NP_001010830.1
Mus musculus (house mouse)	Taar8b	NP_001010837.1
Homo sapiens (human)	TAAR8	NP_444508.1
Bos taurus (cattle)	TAAR8	XP_002690292.1
Mus musculus (house mouse)	Taar8c	NP_001010840.1

Gene Ontology
Bibliography

Related articles in PubMed

Analysis of human TAAR8 and murine Taar8b mediated signaling pathways and expression profile.
M?hlhaus J, Dinter J, N?rnberg D, Rehders M, Depke M, Golchert J, Homuth G, Yi CX, Morin S, K?hrle J, Brix K, Tsch?p M, Kleinau G, Biebermann H
International journal of molecular sciences15(11)20638-55(2014 Nov)

A second class of chemosensory receptors in the olfactory epithelium.
Liberles SD, Buck LB
Nature442(7103)645-50(2006 Aug)

Receptors of mammalian trace amines.
Lewin AH
The AAPS journal8(1)E138-45(2006 Mar)

Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors.
Lindemann L, Ebeling M, Kratochwil NA, Bunzow JR, Grandy DK, Hoener MC
Genomics85(3)372-85(2005 Mar)

Discovery and mapping of ten novel G protein-coupled receptor genes.
Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF
Gene275(1)83-91(2001 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

For the first time is confirmed basal Gi/o signaling activity for TAAR8.
Title: Analysis of human TAAR8 and murine Taar8b mediated signaling pathways and expression profile.

Previous studies reported TAAR expression in brain. This paper found TAAR expression only in olfactory epithelial cells and that each TAAR detects a unique set of amine ligands. TAARs seem to function as a family of chemosensory receptors for amines.
Title: A second class of chemosensory receptors in the olfactory epithelium.

The following TAAR8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TAAR8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29263	NM_053278.2 Latest version!	Homo sapiens trace amine associated receptor 8 (TAAR8), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$144.50-$202.30 $289.00
View Old Accession Versions >>
OHu29263	NM_053278.1	Homo sapiens trace amine associated receptor 8 (TAAR8), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$144.50-$202.30 $289.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TAAR8 ( NM_053278.2 ) cDNA ORF clone, Homo sapiens(Human) -> NP_444508.1 Homo sapiens trace amine associated receptor 8 (TAAR8), mRNA.

Price & Availability↑

CloneID	OHu29263
Clone ID Related Accession (Same CDS sequence)	NM_053278.2 , NM_053278.1
Accession Version	NM_053278.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1029bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Homo sapiens(human)
Product	trace amine-associated receptor 8
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CO920489.1 and CO920393.1. On Jul 22, 2016 this sequence version replaced NM_053278.1. ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGACCAGCA ATTTTTCCCA ACCTGTTGTG CAGCTTTGCT ATGAGGATGT GAATGGATCT 
TGTATTGAAA CTCCCTATTC TCCTGGGTCC CGGGTAATTC TGTACACGGC GTTTAGCTTT 
GGGTCTTTGC TGGCTGTATT TGGAAATCTC TTAGTAATGA CTTCTGTTCT TCATTTTAAG 
CAGCTGCACT CTCCAACCAA TTTTCTCATT GCCTCTCTGG CCTGTGCTGA CTTCTTGGTA 
GGTGTGACTG TGATGCTTTT CAGCATGGTC AGGACGGTGG AGAGCTGCTG GTATTTTGGA 
GCCAAATTTT GTACTCTTCA CAGTTGCTGT GATGTGGCAT TTTGTTACTC TTCTGTCCTC 
CACTTGTGCT TCATCTGCAT CGACAGGTAC ATTGTGGTTA CTGATCCCCT GGTCTATGCT 
ACCAAGTTCA CCGTGTCTGT GTCGGGAATT TGCATCAGCG TGTCCTGGAT TCTGCCTCTC 
ACGTACAGCG GTGCTGTGTT CTACACAGGT GTCAATGATG ATGGGCTGGA GGAATTAGTA 
AGTGCTCTCA ACTGCGTAGG TGGCTGTCAA ATTATTGTAA GTCAAGGCTG GGTGTTGATA 
GATTTTCTGT TATTCTTCAT ACCTACCCTT GTTATGATAA TTCTTTACAG TAAGATTTTT 
CTTATAGCTA AACAACAAGC TATAAAAATT GAAACTACTA GTAGCAAAGT AGAATCATCC 
TCAGAGAGTT ATAAAATCAG AGTGGCCAAG AGAGAGAGGA AAGCAGCTAA AACCCTGGGG 
GTCACGGTAC TAGCATTTGT TATTTCATGG TTACCGTATA CAGTTGATAT ATTAATTGAT 
GCCTTTATGG GCTTCCTGAC CCCTGCCTAT ATCTATGAAA TTTGCTGTTG GAGTGCTTAT 
TATAACTCAG CCATGAATCC TTTGATTTAT GCTCTATTTT ATCCTTGGTT TAGGAAAGCC 
ATAAAACTTA TTTTAAGTGG AGATGTTTTA AAGGCTAGTT CATCAACCAT TAGTTTATTT 
TTAGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_444508.1
CDS	10..1038
Translation	MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE

Target ORF information:

RefSeq Version	NM_053278.2
Organism	Homo sapiens(human)
Definition	Homo sapiens trace amine associated receptor 8 (TAAR8), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053278.2

ORF Insert Sequence:

ATGACCAGCA ATTTTTCCCA ACCTGTTGTG CAGCTTTGCT ATGAGGATGT GAATGGATCT 
TGTATTGAAA CTCCCTATTC TCCTGGGTCC CGGGTAATTC TGTACACGGC GTTTAGCTTT 
GGGTCTTTGC TGGCTGTATT TGGAAATCTC TTAGTAATGA CTTCTGTTCT TCATTTTAAG 
CAGCTGCACT CTCCAACCAA TTTTCTCATT GCCTCTCTGG CCTGTGCTGA CTTCTTGGTA 
GGTGTGACTG TGATGCTTTT CAGCATGGTC AGGACGGTGG AGAGCTGCTG GTATTTTGGA 
GCCAAATTTT GTACTCTTCA CAGTTGCTGT GATGTGGCAT TTTGTTACTC TTCTGTCCTC 
CACTTGTGCT TCATCTGCAT CGACAGGTAC ATTGTGGTTA CTGATCCCCT GGTCTATGCT 
ACCAAGTTCA CCGTGTCTGT GTCGGGAATT TGCATCAGCG TGTCCTGGAT TCTGCCTCTC 
ACGTACAGCG GTGCTGTGTT CTACACAGGT GTCAATGATG ATGGGCTGGA GGAATTAGTA 
AGTGCTCTCA ACTGCGTAGG TGGCTGTCAA ATTATTGTAA GTCAAGGCTG GGTGTTGATA 
GATTTTCTGT TATTCTTCAT ACCTACCCTT GTTATGATAA TTCTTTACAG TAAGATTTTT 
CTTATAGCTA AACAACAAGC TATAAAAATT GAAACTACTA GTAGCAAAGT AGAATCATCC 
TCAGAGAGTT ATAAAATCAG AGTGGCCAAG AGAGAGAGGA AAGCAGCTAA AACCCTGGGG 
GTCACGGTAC TAGCATTTGT TATTTCATGG TTACCGTATA CAGTTGATAT ATTAATTGAT 
GCCTTTATGG GCTTCCTGAC CCCTGCCTAT ATCTATGAAA TTTGCTGTTG GAGTGCTTAT 
TATAACTCAG CCATGAATCC TTTGATTTAT GCTCTATTTT ATCCTTGGTT TAGGAAAGCC 
ATAAAACTTA TTTTAAGTGG AGATGTTTTA AAGGCTAGTT CATCAACCAT TAGTTTATTT 
TTAGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TAAR8 ( NM_053278.1 ) cDNA ORF clone, Homo sapiens(Human) -> NP_444508.1 Homo sapiens trace amine associated receptor 8 (TAAR8), mRNA.

Price & Availability↑

CloneID	OHu29263
Clone ID Related Accession (Same CDS sequence)	NM_053278.2 , NM_053278.1
Accession Version	NM_053278.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1029bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2014-01-25
Organism	Homo sapiens(Human)
Product	trace amine-associated receptor 8
Comment

ATGACCAGCA ATTTTTCCCA ACCTGTTGTG CAGCTTTGCT ATGAGGATGT GAATGGATCT 
TGTATTGAAA CTCCCTATTC TCCTGGGTCC CGGGTAATTC TGTACACGGC GTTTAGCTTT 
GGGTCTTTGC TGGCTGTATT TGGAAATCTC TTAGTAATGA CTTCTGTTCT TCATTTTAAG 
CAGCTGCACT CTCCAACCAA TTTTCTCATT GCCTCTCTGG CCTGTGCTGA CTTCTTGGTA 
GGTGTGACTG TGATGCTTTT CAGCATGGTC AGGACGGTGG AGAGCTGCTG GTATTTTGGA 
GCCAAATTTT GTACTCTTCA CAGTTGCTGT GATGTGGCAT TTTGTTACTC TTCTGTCCTC 
CACTTGTGCT TCATCTGCAT CGACAGGTAC ATTGTGGTTA CTGATCCCCT GGTCTATGCT 
ACCAAGTTCA CCGTGTCTGT GTCGGGAATT TGCATCAGCG TGTCCTGGAT TCTGCCTCTC 
ACGTACAGCG GTGCTGTGTT CTACACAGGT GTCAATGATG ATGGGCTGGA GGAATTAGTA 
AGTGCTCTCA ACTGCGTAGG TGGCTGTCAA ATTATTGTAA GTCAAGGCTG GGTGTTGATA 
GATTTTCTGT TATTCTTCAT ACCTACCCTT GTTATGATAA TTCTTTACAG TAAGATTTTT 
CTTATAGCTA AACAACAAGC TATAAAAATT GAAACTACTA GTAGCAAAGT AGAATCATCC 
TCAGAGAGTT ATAAAATCAG AGTGGCCAAG AGAGAGAGGA AAGCAGCTAA AACCCTGGGG 
GTCACGGTAC TAGCATTTGT TATTTCATGG TTACCGTATA CAGTTGATAT ATTAATTGAT 
GCCTTTATGG GCTTCCTGAC CCCTGCCTAT ATCTATGAAA TTTGCTGTTG GAGTGCTTAT 
TATAACTCAG CCATGAATCC TTTGATTTAT GCTCTATTTT ATCCTTGGTT TAGGAAAGCC 
ATAAAACTTA TTTTAAGTGG AGATGTTTTA AAGGCTAGTT CATCAACCAT TAGTTTATTT 
TTAGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_444508.1
Translation	MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE

Target ORF information:

RefSeq Version	NM_053278.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens trace amine associated receptor 8 (TAAR8), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053278.1

ORF Insert Sequence:

ATGACCAGCA ATTTTTCCCA ACCTGTTGTG CAGCTTTGCT ATGAGGATGT GAATGGATCT 
TGTATTGAAA CTCCCTATTC TCCTGGGTCC CGGGTAATTC TGTACACGGC GTTTAGCTTT 
GGGTCTTTGC TGGCTGTATT TGGAAATCTC TTAGTAATGA CTTCTGTTCT TCATTTTAAG 
CAGCTGCACT CTCCAACCAA TTTTCTCATT GCCTCTCTGG CCTGTGCTGA CTTCTTGGTA 
GGTGTGACTG TGATGCTTTT CAGCATGGTC AGGACGGTGG AGAGCTGCTG GTATTTTGGA 
GCCAAATTTT GTACTCTTCA CAGTTGCTGT GATGTGGCAT TTTGTTACTC TTCTGTCCTC 
CACTTGTGCT TCATCTGCAT CGACAGGTAC ATTGTGGTTA CTGATCCCCT GGTCTATGCT 
ACCAAGTTCA CCGTGTCTGT GTCGGGAATT TGCATCAGCG TGTCCTGGAT TCTGCCTCTC 
ACGTACAGCG GTGCTGTGTT CTACACAGGT GTCAATGATG ATGGGCTGGA GGAATTAGTA 
AGTGCTCTCA ACTGCGTAGG TGGCTGTCAA ATTATTGTAA GTCAAGGCTG GGTGTTGATA 
GATTTTCTGT TATTCTTCAT ACCTACCCTT GTTATGATAA TTCTTTACAG TAAGATTTTT 
CTTATAGCTA AACAACAAGC TATAAAAATT GAAACTACTA GTAGCAAAGT AGAATCATCC 
TCAGAGAGTT ATAAAATCAG AGTGGCCAAG AGAGAGAGGA AAGCAGCTAA AACCCTGGGG 
GTCACGGTAC TAGCATTTGT TATTTCATGG TTACCGTATA CAGTTGATAT ATTAATTGAT 
GCCTTTATGG GCTTCCTGAC CCCTGCCTAT ATCTATGAAA TTTGCTGTTG GAGTGCTTAT 
TATAACTCAG CCATGAATCC TTTGATTTAT GCTCTATTTT ATCCTTGGTT TAGGAAAGCC 
ATAAAACTTA TTTTAAGTGG AGATGTTTTA AAGGCTAGTT CATCAACCAT TAGTTTATTT 
TTAGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Analysis of human TAAR8 and murine Taar8b mediated signaling pathways and expression profile.
International journal of molecular sciences15(11)20638-55(2014 Nov)
M?hlhaus J,Dinter J,N?rnberg D,Rehders M,Depke M,Golchert J,Homuth G,Yi CX,Morin S,K?hrle J,Brix K,Tsch?p M,Kleinau G,Biebermann H

A second class of chemosensory receptors in the olfactory epithelium.
Nature442(7103)645-50(2006 Aug)
Liberles SD,Buck LB

Receptors of mammalian trace amines.
The AAPS journal8(1)E138-45(2006 Mar)
Lewin AH

Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors.
Genomics85(3)372-85(2005 Mar)
Lindemann L,Ebeling M,Kratochwil NA,Bunzow JR,Grandy DK,Hoener MC

Discovery and mapping of ten novel G protein-coupled receptor genes.
Gene275(1)83-91(2001 Sep)
Lee DK,Nguyen T,Lynch KR,Cheng R,Vanti WB,Arkhitko O,Lewis T,Evans JF,George SR,O'Dowd BF

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TAAR8 cDNA ORF clone, Homo sapiens(Human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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