PPP1R3B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PPP1R3B
Entrez Gene ID	79660
Full Name	protein phosphatase 1 regulatory subunit 3B
Synonyms	GL,PPP1R4,PTG
General protein information	Preferred Names protein phosphatase 1 regulatory subunit 3B Names protein phosphatase 1 regulatory subunit 3B PP1 subunit R4 hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL hepatic glycogen-targeting subunit, G(L) protein phosphatase 1 regulatory subunit 4 protein phosphatase 1, regulatory (inhibitor) subunit 3B
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 8 Map Location: 8p23.1
Summary	This gene encodes the catalytic subunit of the serine/theonine phosphatase, protein phosphatase-1. The encoded protein is expressed in liver and skeletal muscle tissue and may be involved in regulating glycogen synthesis in these tissues. This gene may be a involved in type 2 diabetes and maturity-onset diabetes of the young. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Jan 2011].
Disorder MIM:	610541

mRNA and Protein(s)

mRNA	Protein	Name
NM_001201329.1	NP_001188258.1	protein phosphatase 1 regulatory subunit 3B
XM_006716253.2	XP_006716316.1	protein phosphatase 1 regulatory subunit 3B isoform X1
NM_024607.3	NP_078883.2	protein phosphatase 1 regulatory subunit 3B
XM_017013835.1	XP_016869324.1	protein phosphatase 1 regulatory subunit 3B isoform X1
NM_024607.4	NP_078883.2	protein phosphatase 1 regulatory subunit 3B
NM_001201329.2	NP_001188258.1	protein phosphatase 1 regulatory subunit 3B
XM_011543836.1	XP_011542138.1	protein phosphatase 1 regulatory subunit 3B isoform X1
XM_006716253.3	XP_006716316.1	protein phosphatase 1 regulatory subunit 3B isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	PPP1R3B	NP_078883.2
	PPP1R3B	XP_001090588.1
Danio rerio (zebrafish)	ppp1r3b	NP_997874.1
Pan troglodytes (chimpanzee)	PPP1R3B	XP_001136817.1
Xenopus tropicalis (tropical clawed frog)	ppp1r3b	NP_001015950.1
Bos taurus (cattle)	PPP1R3B	NP_001096717.1
Mus musculus (house mouse)	Ppp1r3b	NP_808409.1
Gallus gallus (chicken)	PPP1R3B	XP_420586.2
Caenorhabditis elegans (roundworm)	H18N23.2	NP_741955.2
Canis lupus familiaris (dog)	PPP1R3B	XP_005629965.1
Rattus norvegicus (Norway rat)	Ppp1r3b	NP_620267.2

Gene Ontology
Bibliography

Related articles in PubMed

Relationship between Genetic Variation at PPP1R3B and Liver Glycogen and Triglyceride Levels.
Stender S, Smagris E, Lauridsen BK, Kofoed KF, Nordestgaard BG, Tybjaerg-Hansen A, Pennacchio LA, Dickel DE, Cohen JC, Hobbs HH
Hepatology (Baltimore, Md.)(2017 Dec)

Association between PNPLA3 (rs738409), LYPLAL1 (rs12137855), PPP1R3B (rs4240624), GCKR (rs780094), and elevated transaminase levels in overweight/obese Mexican adults.
Flores YN, Vel?zquez-Cruz R, Ram?rez P, Ba?uelos M, Zhang ZF, Yee HF Jr, Chang SC, Canizales-Quinteros S, Quiterio M, Cabrera-Alvarez G, Pati?o N, Salmer?n J
Molecular biology reports43(12)1359-1369(2016 Dec)

GCKR and PPP1R3B identified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study.
Tin A, Balakrishnan P, Beaty TH, Boerwinkle E, Hoogeveen RC, Young JH, Kao WH
Diabetic medicine : a journal of the British Diabetic Association33(7)968-75(2016 Jul)

Loss of protein targeting to glycogen sensitizes human hepatocellular carcinoma cells towards glucose deprivation mediated oxidative stress and cell death.
Yang R, Zhang M, Gustafson AR, Wang E, Cole MP, Tooley CE, Cheng A
Bioscience reports35(3)(2015 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Among Mexicans, the PNPLA3 (rs738409), LYPLAL1 (rs12137855), PPP1R3B (rs4240624), and GCKR (rs780094) polymorphisms may be associated with a greater risk of chronic liver disease among overweight adults.
Title: Association between PNPLA3 (rs738409), LYPLAL1 (rs12137855), PPP1R3B (rs4240624), GCKR (rs780094), and elevated transaminase levels in overweight/obese Mexican adults.

rs9987289 A-allele was associated with plasma lactate in European-Americans but not in African-Americans.
Title: GCKR and PPP1R3B identified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study.

A novel role for PTG in protecting hepatocellular carcinoma cells from metabolic stress, in part by regulating oxidative stress and autophagy.
Title: Loss of protein targeting to glycogen sensitizes human hepatocellular carcinoma cells towards glucose deprivation mediated oxidative stress and cell death.

Some, but not all, associations between variants in NCAN, lysophospholipase-like 1, GCKR, and PPP1R3B with hepatic steatosis (with and without increased ALT level) were significant within subpopulations.
Title: Association between variants in or near PNPLA3, GCKR, and PPP1R3B with ultrasound-defined steatosis based on data from the third National Health and Nutrition Examination Survey.

Data indicate that genetic polymorphisms of the PPP1R3B gene may contribute to variations in plasma lipids and C-reactive protein (CRP) levels among Chinese Han individuals.
Title: Association of PPP1R3B polymorphisms with blood lipid and C-reactive protein levels in a Chinese population (PPP1R3B C ).

The following PPP1R3B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PPP1R3B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu25150	NM_001201329.2 Latest version!	Homo sapiens protein phosphatase 1 regulatory subunit 3B (PPP1R3B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu25150	NM_024607.4 Latest version!	Homo sapiens protein phosphatase 1 regulatory subunit 3B (PPP1R3B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu25150	XM_011543836.1 Latest version!	Homo sapiens protein phosphatase 1, regulatory subunit 3B (PPP1R3B), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu25150	XM_017013835.1 Latest version!	Homo sapiens protein phosphatase 1 regulatory subunit 3B (PPP1R3B), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu25150	XM_006716253.3 Latest version!	Homo sapiens protein phosphatase 1 regulatory subunit 3B (PPP1R3B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
View Old Accession Versions >>
OHu25150	NM_024607.3	Homo sapiens protein phosphatase 1 regulatory subunit 3B (PPP1R3B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu25150	NM_001201329.1	Homo sapiens protein phosphatase 1 regulatory subunit 3B (PPP1R3B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu25150	XM_006716253.2	Homo sapiens protein phosphatase 1, regulatory subunit 3B (PPP1R3B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PPP1R3B ( NM_001201329.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001188258.1 Homo sapiens protein phosphatase 1 regulatory subunit 3B (PPP1R3B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu25150
Clone ID Related Accession (Same CDS sequence)	NM_001201329.1 , XM_006716253.2 , NM_024607.3 , XM_017013835.1 , NM_024607.4 , NM_001201329.2 , XM_011543836.1 , XM_006716253.3
Accession Version	NM_001201329.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 858bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	protein phosphatase 1 regulatory subunit 3B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB282578.1, BQ431880.1, AC022784.7 and AI263711.1. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.213920.1, AK096119.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END##

ATGATGGCTG TGGACATCGA GTACAGATAC AACTGCATGG CTCCTTCCTT GCGCCAAGAG 
AGGTTTGCCT TTAAGATCTC ACCAAAGCCC AGCAAACCAC TGAGGCCTTG TATTCAGCTG 
AGCAGCAAGA ATGAAGCCAG TGGAATGGTG GCCCCGGCTG TCCAGGAGAA GAAGGTGAAA 
AAGCGGGTGT CCTTCGCAGA CAACCAGGGG CTGGCCCTGA CAATGGTCAA AGTGTTCTCG 
GAATTCGATG ACCCGCTAGA TATGCCATTC AACATCACCG AGCTCCTAGA CAACATTGTG 
AGCTTGACGA CAGCAGAGAG CGAGAGCTTT GTTCTGGATT TTTCCCAGCC CTCTGCAGAT 
TACTTAGACT TTAGAAATCG ACTTCAGGCC GACCACGTCT GCCTTGAGAA CTGTGTGCTC 
AAGGACAAGG CCATTGCAGG CACTGTGAAG GTTCAGAACC TCGCATTTGA GAAGACCGTG 
AAAATAAGGA TGACGTTCGA CACCTGGAAG AGCTACACAG ACTTTCCTTG TCAGTACGTG 
AAGGACACTT ATGCCGGTTC AGACAGGGAC ACGTTCTCCT TCGACATCAG CTTGCCCGAG 
AAGATTCAGT CTTATGAAAG AATGGAGTTT GCTGTGTACT ACGAGTGCAA TGGACAGACG 
TACTGGGACA GCAACAGAGG CAAGAACTAT AGGATCATCC GGGCTGAGTT AAAATCTACC 
CAGGGAATGA CCAAGCCCCA CAGTGGACCG GATTTGGGAA TATCCTTTGA CCAGTTCGGA 
AGCCCTCGGT GTTCCTATGG TCTGTTTCCA GAGTGGCCAA GTTACTTAGG ATATGAAAAG 
CTAGGGCCCT ACTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001188258.1
CDS	314..1171
Translation	MMAVDIEYRYNCMAPSLRQERFAFKISPKPSKPLRPCIQLSSKNEASGMVAPAVQEKKVKKRVSFADNQGLALTMVKVFSEFDDPLDMPFNITELLDNIVSLTTAESESFVLDFSQPSADYLDFRNRLQADHVCLENCVLKDKAIAGTVKVQNLAFEKTVKIRMTFDTWKSYTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSYERMEFAVYYECNGQTYWDSNRGKNYRIIRAELKSTQGMTKPHSGPDLGISFDQFGSPRCSYGLFPEWPSYLGYEKLGPYY

Target ORF information:

RefSeq Version	NM_001201329.1
Organism	Homo sapiens(human)
Definition	Homo sapiens protein phosphatase 1 regulatory subunit 3B (PPP1R3B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001201329.1

ORF Insert Sequence:

ATGATGGCTG TGGACATCGA GTACAGATAC AACTGCATGG CTCCTTCCTT GCGCCAAGAG 
AGGTTTGCCT TTAAGATCTC ACCAAAGCCC AGCAAACCAC TGAGGCCTTG TATTCAGCTG 
AGCAGCAAGA ATGAAGCCAG TGGAATGGTG GCCCCGGCTG TCCAGGAGAA GAAGGTGAAA 
AAGCGGGTGT CCTTCGCAGA CAACCAGGGG CTGGCCCTGA CAATGGTCAA AGTGTTCTCG 
GAATTCGATG ACCCGCTAGA TATGCCATTC AACATCACCG AGCTCCTAGA CAACATTGTG 
AGCTTGACGA CAGCAGAGAG CGAGAGCTTT GTTCTGGATT TTTCCCAGCC CTCTGCAGAT 
TACTTAGACT TTAGAAATCG ACTTCAGGCC GACCACGTCT GCCTTGAGAA CTGTGTGCTC 
AAGGACAAGG CCATTGCAGG CACTGTGAAG GTTCAGAACC TCGCATTTGA GAAGACCGTG 
AAAATAAGGA TGACGTTCGA CACCTGGAAG AGCTACACAG ACTTTCCTTG TCAGTACGTG 
AAGGACACTT ATGCCGGTTC AGACAGGGAC ACGTTCTCCT TCGACATCAG CTTGCCCGAG 
AAGATTCAGT CTTATGAAAG AATGGAGTTT GCTGTGTACT ACGAGTGCAA TGGACAGACG 
TACTGGGACA GCAACAGAGG CAAGAACTAT AGGATCATCC GGGCTGAGTT AAAATCTACC 
CAGGGAATGA CCAAGCCCCA CAGTGGACCG GATTTGGGAA TATCCTTTGA CCAGTTCGGA 
AGCCCTCGGT GTTCCTATGG TCTGTTTCCA GAGTGGCCAA GTTACTTAGG ATATGAAAAG 
CTAGGGCCCT ACTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PPP1R3B ( NM_024607.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_078883.2 Homo sapiens protein phosphatase 1 regulatory subunit 3B (PPP1R3B), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu25150
Clone ID Related Accession (Same CDS sequence)	NM_001201329.1 , XM_006716253.2 , NM_024607.3 , XM_017013835.1 , NM_024607.4 , NM_001201329.2 , XM_011543836.1 , XM_006716253.3
Accession Version	NM_024607.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 858bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	protein phosphatase 1 regulatory subunit 3B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA100998.1, BQ431880.1, AC022784.7 and AI263711.1. On Jan 13, 2011 this sequence version replaced NM_024607.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DA100998.1, SRR1803611.103671.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145245, SAMN03267757 [ECO:0000348] ##Evidence-Data-END##

ATGATGGCTG TGGACATCGA GTACAGATAC AACTGCATGG CTCCTTCCTT GCGCCAAGAG 
AGGTTTGCCT TTAAGATCTC ACCAAAGCCC AGCAAACCAC TGAGGCCTTG TATTCAGCTG 
AGCAGCAAGA ATGAAGCCAG TGGAATGGTG GCCCCGGCTG TCCAGGAGAA GAAGGTGAAA 
AAGCGGGTGT CCTTCGCAGA CAACCAGGGG CTGGCCCTGA CAATGGTCAA AGTGTTCTCG 
GAATTCGATG ACCCGCTAGA TATGCCATTC AACATCACCG AGCTCCTAGA CAACATTGTG 
AGCTTGACGA CAGCAGAGAG CGAGAGCTTT GTTCTGGATT TTTCCCAGCC CTCTGCAGAT 
TACTTAGACT TTAGAAATCG ACTTCAGGCC GACCACGTCT GCCTTGAGAA CTGTGTGCTC 
AAGGACAAGG CCATTGCAGG CACTGTGAAG GTTCAGAACC TCGCATTTGA GAAGACCGTG 
AAAATAAGGA TGACGTTCGA CACCTGGAAG AGCTACACAG ACTTTCCTTG TCAGTACGTG 
AAGGACACTT ATGCCGGTTC AGACAGGGAC ACGTTCTCCT TCGACATCAG CTTGCCCGAG 
AAGATTCAGT CTTATGAAAG AATGGAGTTT GCTGTGTACT ACGAGTGCAA TGGACAGACG 
TACTGGGACA GCAACAGAGG CAAGAACTAT AGGATCATCC GGGCTGAGTT AAAATCTACC 
CAGGGAATGA CCAAGCCCCA CAGTGGACCG GATTTGGGAA TATCCTTTGA CCAGTTCGGA 
AGCCCTCGGT GTTCCTATGG TCTGTTTCCA GAGTGGCCAA GTTACTTAGG ATATGAAAAG 
CTAGGGCCCT ACTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078883.2
CDS	166..1023
Translation	MMAVDIEYRYNCMAPSLRQERFAFKISPKPSKPLRPCIQLSSKNEASGMVAPAVQEKKVKKRVSFADNQGLALTMVKVFSEFDDPLDMPFNITELLDNIVSLTTAESESFVLDFSQPSADYLDFRNRLQADHVCLENCVLKDKAIAGTVKVQNLAFEKTVKIRMTFDTWKSYTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSYERMEFAVYYECNGQTYWDSNRGKNYRIIRAELKSTQGMTKPHSGPDLGISFDQFGSPRCSYGLFPEWPSYLGYEKLGPYY

Target ORF information:

RefSeq Version	NM_024607.3
Organism	Homo sapiens(human)
Definition	Homo sapiens protein phosphatase 1 regulatory subunit 3B (PPP1R3B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024607.3

ORF Insert Sequence:

ATGATGGCTG TGGACATCGA GTACAGATAC AACTGCATGG CTCCTTCCTT GCGCCAAGAG 
AGGTTTGCCT TTAAGATCTC ACCAAAGCCC AGCAAACCAC TGAGGCCTTG TATTCAGCTG 
AGCAGCAAGA ATGAAGCCAG TGGAATGGTG GCCCCGGCTG TCCAGGAGAA GAAGGTGAAA 
AAGCGGGTGT CCTTCGCAGA CAACCAGGGG CTGGCCCTGA CAATGGTCAA AGTGTTCTCG 
GAATTCGATG ACCCGCTAGA TATGCCATTC AACATCACCG AGCTCCTAGA CAACATTGTG 
AGCTTGACGA CAGCAGAGAG CGAGAGCTTT GTTCTGGATT TTTCCCAGCC CTCTGCAGAT 
TACTTAGACT TTAGAAATCG ACTTCAGGCC GACCACGTCT GCCTTGAGAA CTGTGTGCTC 
AAGGACAAGG CCATTGCAGG CACTGTGAAG GTTCAGAACC TCGCATTTGA GAAGACCGTG 
AAAATAAGGA TGACGTTCGA CACCTGGAAG AGCTACACAG ACTTTCCTTG TCAGTACGTG 
AAGGACACTT ATGCCGGTTC AGACAGGGAC ACGTTCTCCT TCGACATCAG CTTGCCCGAG 
AAGATTCAGT CTTATGAAAG AATGGAGTTT GCTGTGTACT ACGAGTGCAA TGGACAGACG 
TACTGGGACA GCAACAGAGG CAAGAACTAT AGGATCATCC GGGCTGAGTT AAAATCTACC 
CAGGGAATGA CCAAGCCCCA CAGTGGACCG GATTTGGGAA TATCCTTTGA CCAGTTCGGA 
AGCCCTCGGT GTTCCTATGG TCTGTTTCCA GAGTGGCCAA GTTACTTAGG ATATGAAAAG 
CTAGGGCCCT ACTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PPP1R3B ( NM_024607.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_078883.2 Homo sapiens protein phosphatase 1 regulatory subunit 3B (PPP1R3B), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu25150
Clone ID Related Accession (Same CDS sequence)	NM_001201329.1 , XM_006716253.2 , NM_024607.3 , XM_017013835.1 , NM_024607.4 , NM_001201329.2 , XM_011543836.1 , XM_006716253.3
Accession Version	NM_024607.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 858bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	protein phosphatase 1 regulatory subunit 3B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA100998.1, BQ431880.1, AC022784.7 and AI263711.1. On Nov 22, 2018 this sequence version replaced NM_024607.3. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BP233331.1, AK024067.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145245, SAMN03267757 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000310455.4/ ENSP00000308318.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGATGGCTG TGGACATCGA GTACAGATAC AACTGCATGG CTCCTTCCTT GCGCCAAGAG 
AGGTTTGCCT TTAAGATCTC ACCAAAGCCC AGCAAACCAC TGAGGCCTTG TATTCAGCTG 
AGCAGCAAGA ATGAAGCCAG TGGAATGGTG GCCCCGGCTG TCCAGGAGAA GAAGGTGAAA 
AAGCGGGTGT CCTTCGCAGA CAACCAGGGG CTGGCCCTGA CAATGGTCAA AGTGTTCTCG 
GAATTCGATG ACCCGCTAGA TATGCCATTC AACATCACCG AGCTCCTAGA CAACATTGTG 
AGCTTGACGA CAGCAGAGAG CGAGAGCTTT GTTCTGGATT TTTCCCAGCC CTCTGCAGAT 
TACTTAGACT TTAGAAATCG ACTTCAGGCC GACCACGTCT GCCTTGAGAA CTGTGTGCTC 
AAGGACAAGG CCATTGCAGG CACTGTGAAG GTTCAGAACC TCGCATTTGA GAAGACCGTG 
AAAATAAGGA TGACGTTCGA CACCTGGAAG AGCTACACAG ACTTTCCTTG TCAGTACGTG 
AAGGACACTT ATGCCGGTTC AGACAGGGAC ACGTTCTCCT TCGACATCAG CTTGCCCGAG 
AAGATTCAGT CTTATGAAAG AATGGAGTTT GCTGTGTACT ACGAGTGCAA TGGACAGACG 
TACTGGGACA GCAACAGAGG CAAGAACTAT AGGATCATCC GGGCTGAGTT AAAATCTACC 
CAGGGAATGA CCAAGCCCCA CAGTGGACCG GATTTGGGAA TATCCTTTGA CCAGTTCGGA 
AGCCCTCGGT GTTCCTATGG TCTGTTTCCA GAGTGGCCAA GTTACTTAGG ATATGAAAAG 
CTAGGGCCCT ACTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078883.2
CDS	114..971
Translation	MMAVDIEYRYNCMAPSLRQERFAFKISPKPSKPLRPCIQLSSKNEASGMVAPAVQEKKVKKRVSFADNQGLALTMVKVFSEFDDPLDMPFNITELLDNIVSLTTAESESFVLDFSQPSADYLDFRNRLQADHVCLENCVLKDKAIAGTVKVQNLAFEKTVKIRMTFDTWKSYTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSYERMEFAVYYECNGQTYWDSNRGKNYRIIRAELKSTQGMTKPHSGPDLGISFDQFGSPRCSYGLFPEWPSYLGYEKLGPYY

Target ORF information:

RefSeq Version	NM_024607.4
Organism	Homo sapiens(human)
Definition	Homo sapiens protein phosphatase 1 regulatory subunit 3B (PPP1R3B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024607.4

ORF Insert Sequence:

ATGATGGCTG TGGACATCGA GTACAGATAC AACTGCATGG CTCCTTCCTT GCGCCAAGAG 
AGGTTTGCCT TTAAGATCTC ACCAAAGCCC AGCAAACCAC TGAGGCCTTG TATTCAGCTG 
AGCAGCAAGA ATGAAGCCAG TGGAATGGTG GCCCCGGCTG TCCAGGAGAA GAAGGTGAAA 
AAGCGGGTGT CCTTCGCAGA CAACCAGGGG CTGGCCCTGA CAATGGTCAA AGTGTTCTCG 
GAATTCGATG ACCCGCTAGA TATGCCATTC AACATCACCG AGCTCCTAGA CAACATTGTG 
AGCTTGACGA CAGCAGAGAG CGAGAGCTTT GTTCTGGATT TTTCCCAGCC CTCTGCAGAT 
TACTTAGACT TTAGAAATCG ACTTCAGGCC GACCACGTCT GCCTTGAGAA CTGTGTGCTC 
AAGGACAAGG CCATTGCAGG CACTGTGAAG GTTCAGAACC TCGCATTTGA GAAGACCGTG 
AAAATAAGGA TGACGTTCGA CACCTGGAAG AGCTACACAG ACTTTCCTTG TCAGTACGTG 
AAGGACACTT ATGCCGGTTC AGACAGGGAC ACGTTCTCCT TCGACATCAG CTTGCCCGAG 
AAGATTCAGT CTTATGAAAG AATGGAGTTT GCTGTGTACT ACGAGTGCAA TGGACAGACG 
TACTGGGACA GCAACAGAGG CAAGAACTAT AGGATCATCC GGGCTGAGTT AAAATCTACC 
CAGGGAATGA CCAAGCCCCA CAGTGGACCG GATTTGGGAA TATCCTTTGA CCAGTTCGGA 
AGCCCTCGGT GTTCCTATGG TCTGTTTCCA GAGTGGCCAA GTTACTTAGG ATATGAAAAG 
CTAGGGCCCT ACTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PPP1R3B ( NM_001201329.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001188258.1 Homo sapiens protein phosphatase 1 regulatory subunit 3B (PPP1R3B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu25150
Clone ID Related Accession (Same CDS sequence)	NM_001201329.1 , XM_006716253.2 , NM_024607.3 , XM_017013835.1 , NM_024607.4 , NM_001201329.2 , XM_011543836.1 , XM_006716253.3
Accession Version	NM_001201329.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 858bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	protein phosphatase 1 regulatory subunit 3B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB282578.1, BQ431880.1, AC022784.7 and AI263711.1. This sequence is a reference standard in the RefSeqGene project. On May 31, 2019 this sequence version replaced NM_001201329.1. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DRR138518.342749.1, AK096119.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END##

ATGATGGCTG TGGACATCGA GTACAGATAC AACTGCATGG CTCCTTCCTT GCGCCAAGAG 
AGGTTTGCCT TTAAGATCTC ACCAAAGCCC AGCAAACCAC TGAGGCCTTG TATTCAGCTG 
AGCAGCAAGA ATGAAGCCAG TGGAATGGTG GCCCCGGCTG TCCAGGAGAA GAAGGTGAAA 
AAGCGGGTGT CCTTCGCAGA CAACCAGGGG CTGGCCCTGA CAATGGTCAA AGTGTTCTCG 
GAATTCGATG ACCCGCTAGA TATGCCATTC AACATCACCG AGCTCCTAGA CAACATTGTG 
AGCTTGACGA CAGCAGAGAG CGAGAGCTTT GTTCTGGATT TTTCCCAGCC CTCTGCAGAT 
TACTTAGACT TTAGAAATCG ACTTCAGGCC GACCACGTCT GCCTTGAGAA CTGTGTGCTC 
AAGGACAAGG CCATTGCAGG CACTGTGAAG GTTCAGAACC TCGCATTTGA GAAGACCGTG 
AAAATAAGGA TGACGTTCGA CACCTGGAAG AGCTACACAG ACTTTCCTTG TCAGTACGTG 
AAGGACACTT ATGCCGGTTC AGACAGGGAC ACGTTCTCCT TCGACATCAG CTTGCCCGAG 
AAGATTCAGT CTTATGAAAG AATGGAGTTT GCTGTGTACT ACGAGTGCAA TGGACAGACG 
TACTGGGACA GCAACAGAGG CAAGAACTAT AGGATCATCC GGGCTGAGTT AAAATCTACC 
CAGGGAATGA CCAAGCCCCA CAGTGGACCG GATTTGGGAA TATCCTTTGA CCAGTTCGGA 
AGCCCTCGGT GTTCCTATGG TCTGTTTCCA GAGTGGCCAA GTTACTTAGG ATATGAAAAG 
CTAGGGCCCT ACTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001188258.1
CDS	211..1068
Translation	MMAVDIEYRYNCMAPSLRQERFAFKISPKPSKPLRPCIQLSSKNEASGMVAPAVQEKKVKKRVSFADNQGLALTMVKVFSEFDDPLDMPFNITELLDNIVSLTTAESESFVLDFSQPSADYLDFRNRLQADHVCLENCVLKDKAIAGTVKVQNLAFEKTVKIRMTFDTWKSYTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSYERMEFAVYYECNGQTYWDSNRGKNYRIIRAELKSTQGMTKPHSGPDLGISFDQFGSPRCSYGLFPEWPSYLGYEKLGPYY

Target ORF information:

RefSeq Version	NM_001201329.2
Organism	Homo sapiens(human)
Definition	Homo sapiens protein phosphatase 1 regulatory subunit 3B (PPP1R3B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001201329.2

ORF Insert Sequence:

ATGATGGCTG TGGACATCGA GTACAGATAC AACTGCATGG CTCCTTCCTT GCGCCAAGAG 
AGGTTTGCCT TTAAGATCTC ACCAAAGCCC AGCAAACCAC TGAGGCCTTG TATTCAGCTG 
AGCAGCAAGA ATGAAGCCAG TGGAATGGTG GCCCCGGCTG TCCAGGAGAA GAAGGTGAAA 
AAGCGGGTGT CCTTCGCAGA CAACCAGGGG CTGGCCCTGA CAATGGTCAA AGTGTTCTCG 
GAATTCGATG ACCCGCTAGA TATGCCATTC AACATCACCG AGCTCCTAGA CAACATTGTG 
AGCTTGACGA CAGCAGAGAG CGAGAGCTTT GTTCTGGATT TTTCCCAGCC CTCTGCAGAT 
TACTTAGACT TTAGAAATCG ACTTCAGGCC GACCACGTCT GCCTTGAGAA CTGTGTGCTC 
AAGGACAAGG CCATTGCAGG CACTGTGAAG GTTCAGAACC TCGCATTTGA GAAGACCGTG 
AAAATAAGGA TGACGTTCGA CACCTGGAAG AGCTACACAG ACTTTCCTTG TCAGTACGTG 
AAGGACACTT ATGCCGGTTC AGACAGGGAC ACGTTCTCCT TCGACATCAG CTTGCCCGAG 
AAGATTCAGT CTTATGAAAG AATGGAGTTT GCTGTGTACT ACGAGTGCAA TGGACAGACG 
TACTGGGACA GCAACAGAGG CAAGAACTAT AGGATCATCC GGGCTGAGTT AAAATCTACC 
CAGGGAATGA CCAAGCCCCA CAGTGGACCG GATTTGGGAA TATCCTTTGA CCAGTTCGGA 
AGCCCTCGGT GTTCCTATGG TCTGTTTCCA GAGTGGCCAA GTTACTTAGG ATATGAAAAG 
CTAGGGCCCT ACTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PPP1R3B ( XM_006716253.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_006716316.1 Homo sapiens protein phosphatase 1, regulatory subunit 3B (PPP1R3B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu25150
Clone ID Related Accession (Same CDS sequence)	NM_001201329.1 , XM_006716253.2 , NM_024607.3 , XM_017013835.1 , NM_024607.4 , NM_001201329.2 , XM_011543836.1 , XM_006716253.3
Accession Version	XM_006716253.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 858bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	protein phosphatase 1 regulatory subunit 3B isoform X1
Comment

ATGATGGCTG TGGACATCGA GTACAGATAC AACTGCATGG CTCCTTCCTT GCGCCAAGAG 
AGGTTTGCCT TTAAGATCTC ACCAAAGCCC AGCAAACCAC TGAGGCCTTG TATTCAGCTG 
AGCAGCAAGA ATGAAGCCAG TGGAATGGTG GCCCCGGCTG TCCAGGAGAA GAAGGTGAAA 
AAGCGGGTGT CCTTCGCAGA CAACCAGGGG CTGGCCCTGA CAATGGTCAA AGTGTTCTCG 
GAATTCGATG ACCCGCTAGA TATGCCATTC AACATCACCG AGCTCCTAGA CAACATTGTG 
AGCTTGACGA CAGCAGAGAG CGAGAGCTTT GTTCTGGATT TTTCCCAGCC CTCTGCAGAT 
TACTTAGACT TTAGAAATCG ACTTCAGGCC GACCACGTCT GCCTTGAGAA CTGTGTGCTC 
AAGGACAAGG CCATTGCAGG CACTGTGAAG GTTCAGAACC TCGCATTTGA GAAGACCGTG 
AAAATAAGGA TGACGTTCGA CACCTGGAAG AGCTACACAG ACTTTCCTTG TCAGTACGTG 
AAGGACACTT ATGCCGGTTC AGACAGGGAC ACGTTCTCCT TCGACATCAG CTTGCCCGAG 
AAGATTCAGT CTTATGAAAG AATGGAGTTT GCTGTGTACT ACGAGTGCAA TGGACAGACG 
TACTGGGACA GCAACAGAGG CAAGAACTAT AGGATCATCC GGGCTGAGTT AAAATCTACC 
CAGGGAATGA CCAAGCCCCA CAGTGGACCG GATTTGGGAA TATCCTTTGA CCAGTTCGGA 
AGCCCTCGGT GTTCCTATGG TCTGTTTCCA GAGTGGCCAA GTTACTTAGG ATATGAAAAG 
CTAGGGCCCT ACTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006716316.1
Translation	MMAVDIEYRYNCMAPSLRQERFAFKISPKPSKPLRPCIQLSSKNEASGMVAPAVQEKKVKKRVSFADNQGLALTMVKVFSEFDDPLDMPFNITELLDNIVSLTTAESESFVLDFSQPSADYLDFRNRLQADHVCLENCVLKDKAIAGTVKVQNLAFEKTVKIRMTFDTWKSYTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSYERMEFAVYYECNGQTYWDSNRGKNYRIIRAELKSTQGMTKPHSGPDLGISFDQFGSPRCSYGLFPEWPSYLGYEKLGPYY

Target ORF information:

RefSeq Version	XM_006716253.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens protein phosphatase 1, regulatory subunit 3B (PPP1R3B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006716253.2

ORF Insert Sequence:

ATGATGGCTG TGGACATCGA GTACAGATAC AACTGCATGG CTCCTTCCTT GCGCCAAGAG 
AGGTTTGCCT TTAAGATCTC ACCAAAGCCC AGCAAACCAC TGAGGCCTTG TATTCAGCTG 
AGCAGCAAGA ATGAAGCCAG TGGAATGGTG GCCCCGGCTG TCCAGGAGAA GAAGGTGAAA 
AAGCGGGTGT CCTTCGCAGA CAACCAGGGG CTGGCCCTGA CAATGGTCAA AGTGTTCTCG 
GAATTCGATG ACCCGCTAGA TATGCCATTC AACATCACCG AGCTCCTAGA CAACATTGTG 
AGCTTGACGA CAGCAGAGAG CGAGAGCTTT GTTCTGGATT TTTCCCAGCC CTCTGCAGAT 
TACTTAGACT TTAGAAATCG ACTTCAGGCC GACCACGTCT GCCTTGAGAA CTGTGTGCTC 
AAGGACAAGG CCATTGCAGG CACTGTGAAG GTTCAGAACC TCGCATTTGA GAAGACCGTG 
AAAATAAGGA TGACGTTCGA CACCTGGAAG AGCTACACAG ACTTTCCTTG TCAGTACGTG 
AAGGACACTT ATGCCGGTTC AGACAGGGAC ACGTTCTCCT TCGACATCAG CTTGCCCGAG 
AAGATTCAGT CTTATGAAAG AATGGAGTTT GCTGTGTACT ACGAGTGCAA TGGACAGACG 
TACTGGGACA GCAACAGAGG CAAGAACTAT AGGATCATCC GGGCTGAGTT AAAATCTACC 
CAGGGAATGA CCAAGCCCCA CAGTGGACCG GATTTGGGAA TATCCTTTGA CCAGTTCGGA 
AGCCCTCGGT GTTCCTATGG TCTGTTTCCA GAGTGGCCAA GTTACTTAGG ATATGAAAAG 
CTAGGGCCCT ACTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PPP1R3B ( XM_017013835.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016869324.1 Homo sapiens protein phosphatase 1 regulatory subunit 3B (PPP1R3B), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu25150
Clone ID Related Accession (Same CDS sequence)	NM_001201329.1 , XM_006716253.2 , NM_024607.3 , XM_017013835.1 , NM_024607.4 , NM_001201329.2 , XM_011543836.1 , XM_006716253.3
Accession Version	XM_017013835.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 858bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein phosphatase 1 regulatory subunit 3B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGGCTG TGGACATCGA GTACAGATAC AACTGCATGG CTCCTTCCTT GCGCCAAGAG 
AGGTTTGCCT TTAAGATCTC ACCAAAGCCC AGCAAACCAC TGAGGCCTTG TATTCAGCTG 
AGCAGCAAGA ATGAAGCCAG TGGAATGGTG GCCCCGGCTG TCCAGGAGAA GAAGGTGAAA 
AAGCGGGTGT CCTTCGCAGA CAACCAGGGG CTGGCCCTGA CAATGGTCAA AGTGTTCTCG 
GAATTCGATG ACCCGCTAGA TATGCCATTC AACATCACCG AGCTCCTAGA CAACATTGTG 
AGCTTGACGA CAGCAGAGAG CGAGAGCTTT GTTCTGGATT TTTCCCAGCC CTCTGCAGAT 
TACTTAGACT TTAGAAATCG ACTTCAGGCC GACCACGTCT GCCTTGAGAA CTGTGTGCTC 
AAGGACAAGG CCATTGCAGG CACTGTGAAG GTTCAGAACC TCGCATTTGA GAAGACCGTG 
AAAATAAGGA TGACGTTCGA CACCTGGAAG AGCTACACAG ACTTTCCTTG TCAGTACGTG 
AAGGACACTT ATGCCGGTTC AGACAGGGAC ACGTTCTCCT TCGACATCAG CTTGCCCGAG 
AAGATTCAGT CTTATGAAAG AATGGAGTTT GCTGTGTACT ACGAGTGCAA TGGACAGACG 
TACTGGGACA GCAACAGAGG CAAGAACTAT AGGATCATCC GGGCTGAGTT AAAATCTACC 
CAGGGAATGA CCAAGCCCCA CAGTGGACCG GATTTGGGAA TATCCTTTGA CCAGTTCGGA 
AGCCCTCGGT GTTCCTATGG TCTGTTTCCA GAGTGGCCAA GTTACTTAGG ATATGAAAAG 
CTAGGGCCCT ACTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016869324.1
CDS	266..1123
Translation	MMAVDIEYRYNCMAPSLRQERFAFKISPKPSKPLRPCIQLSSKNEASGMVAPAVQEKKVKKRVSFADNQGLALTMVKVFSEFDDPLDMPFNITELLDNIVSLTTAESESFVLDFSQPSADYLDFRNRLQADHVCLENCVLKDKAIAGTVKVQNLAFEKTVKIRMTFDTWKSYTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSYERMEFAVYYECNGQTYWDSNRGKNYRIIRAELKSTQGMTKPHSGPDLGISFDQFGSPRCSYGLFPEWPSYLGYEKLGPYY

Target ORF information:

RefSeq Version	XM_017013835.1
Organism	Homo sapiens(human)
Definition	Homo sapiens protein phosphatase 1 regulatory subunit 3B (PPP1R3B), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017013835.1

ORF Insert Sequence:

ATGATGGCTG TGGACATCGA GTACAGATAC AACTGCATGG CTCCTTCCTT GCGCCAAGAG 
AGGTTTGCCT TTAAGATCTC ACCAAAGCCC AGCAAACCAC TGAGGCCTTG TATTCAGCTG 
AGCAGCAAGA ATGAAGCCAG TGGAATGGTG GCCCCGGCTG TCCAGGAGAA GAAGGTGAAA 
AAGCGGGTGT CCTTCGCAGA CAACCAGGGG CTGGCCCTGA CAATGGTCAA AGTGTTCTCG 
GAATTCGATG ACCCGCTAGA TATGCCATTC AACATCACCG AGCTCCTAGA CAACATTGTG 
AGCTTGACGA CAGCAGAGAG CGAGAGCTTT GTTCTGGATT TTTCCCAGCC CTCTGCAGAT 
TACTTAGACT TTAGAAATCG ACTTCAGGCC GACCACGTCT GCCTTGAGAA CTGTGTGCTC 
AAGGACAAGG CCATTGCAGG CACTGTGAAG GTTCAGAACC TCGCATTTGA GAAGACCGTG 
AAAATAAGGA TGACGTTCGA CACCTGGAAG AGCTACACAG ACTTTCCTTG TCAGTACGTG 
AAGGACACTT ATGCCGGTTC AGACAGGGAC ACGTTCTCCT TCGACATCAG CTTGCCCGAG 
AAGATTCAGT CTTATGAAAG AATGGAGTTT GCTGTGTACT ACGAGTGCAA TGGACAGACG 
TACTGGGACA GCAACAGAGG CAAGAACTAT AGGATCATCC GGGCTGAGTT AAAATCTACC 
CAGGGAATGA CCAAGCCCCA CAGTGGACCG GATTTGGGAA TATCCTTTGA CCAGTTCGGA 
AGCCCTCGGT GTTCCTATGG TCTGTTTCCA GAGTGGCCAA GTTACTTAGG ATATGAAAAG 
CTAGGGCCCT ACTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PPP1R3B ( XM_011543836.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011542138.1 Homo sapiens protein phosphatase 1, regulatory subunit 3B (PPP1R3B), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu25150
Clone ID Related Accession (Same CDS sequence)	NM_001201329.1 , XM_006716253.2 , NM_024607.3 , XM_017013835.1 , NM_024607.4 , NM_001201329.2 , XM_011543836.1 , XM_006716253.3
Accession Version	XM_011543836.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 858bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	protein phosphatase 1 regulatory subunit 3B isoform X1
Comment

ATGATGGCTG TGGACATCGA GTACAGATAC AACTGCATGG CTCCTTCCTT GCGCCAAGAG 
AGGTTTGCCT TTAAGATCTC ACCAAAGCCC AGCAAACCAC TGAGGCCTTG TATTCAGCTG 
AGCAGCAAGA ATGAAGCCAG TGGAATGGTG GCCCCGGCTG TCCAGGAGAA GAAGGTGAAA 
AAGCGGGTGT CCTTCGCAGA CAACCAGGGG CTGGCCCTGA CAATGGTCAA AGTGTTCTCG 
GAATTCGATG ACCCGCTAGA TATGCCATTC AACATCACCG AGCTCCTAGA CAACATTGTG 
AGCTTGACGA CAGCAGAGAG CGAGAGCTTT GTTCTGGATT TTTCCCAGCC CTCTGCAGAT 
TACTTAGACT TTAGAAATCG ACTTCAGGCC GACCACGTCT GCCTTGAGAA CTGTGTGCTC 
AAGGACAAGG CCATTGCAGG CACTGTGAAG GTTCAGAACC TCGCATTTGA GAAGACCGTG 
AAAATAAGGA TGACGTTCGA CACCTGGAAG AGCTACACAG ACTTTCCTTG TCAGTACGTG 
AAGGACACTT ATGCCGGTTC AGACAGGGAC ACGTTCTCCT TCGACATCAG CTTGCCCGAG 
AAGATTCAGT CTTATGAAAG AATGGAGTTT GCTGTGTACT ACGAGTGCAA TGGACAGACG 
TACTGGGACA GCAACAGAGG CAAGAACTAT AGGATCATCC GGGCTGAGTT AAAATCTACC 
CAGGGAATGA CCAAGCCCCA CAGTGGACCG GATTTGGGAA TATCCTTTGA CCAGTTCGGA 
AGCCCTCGGT GTTCCTATGG TCTGTTTCCA GAGTGGCCAA GTTACTTAGG ATATGAAAAG 
CTAGGGCCCT ACTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011542138.1
Translation	MMAVDIEYRYNCMAPSLRQERFAFKISPKPSKPLRPCIQLSSKNEASGMVAPAVQEKKVKKRVSFADNQGLALTMVKVFSEFDDPLDMPFNITELLDNIVSLTTAESESFVLDFSQPSADYLDFRNRLQADHVCLENCVLKDKAIAGTVKVQNLAFEKTVKIRMTFDTWKSYTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSYERMEFAVYYECNGQTYWDSNRGKNYRIIRAELKSTQGMTKPHSGPDLGISFDQFGSPRCSYGLFPEWPSYLGYEKLGPYY

Target ORF information:

RefSeq Version	XM_011543836.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens protein phosphatase 1, regulatory subunit 3B (PPP1R3B), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011543836.1

ORF Insert Sequence:

ATGATGGCTG TGGACATCGA GTACAGATAC AACTGCATGG CTCCTTCCTT GCGCCAAGAG 
AGGTTTGCCT TTAAGATCTC ACCAAAGCCC AGCAAACCAC TGAGGCCTTG TATTCAGCTG 
AGCAGCAAGA ATGAAGCCAG TGGAATGGTG GCCCCGGCTG TCCAGGAGAA GAAGGTGAAA 
AAGCGGGTGT CCTTCGCAGA CAACCAGGGG CTGGCCCTGA CAATGGTCAA AGTGTTCTCG 
GAATTCGATG ACCCGCTAGA TATGCCATTC AACATCACCG AGCTCCTAGA CAACATTGTG 
AGCTTGACGA CAGCAGAGAG CGAGAGCTTT GTTCTGGATT TTTCCCAGCC CTCTGCAGAT 
TACTTAGACT TTAGAAATCG ACTTCAGGCC GACCACGTCT GCCTTGAGAA CTGTGTGCTC 
AAGGACAAGG CCATTGCAGG CACTGTGAAG GTTCAGAACC TCGCATTTGA GAAGACCGTG 
AAAATAAGGA TGACGTTCGA CACCTGGAAG AGCTACACAG ACTTTCCTTG TCAGTACGTG 
AAGGACACTT ATGCCGGTTC AGACAGGGAC ACGTTCTCCT TCGACATCAG CTTGCCCGAG 
AAGATTCAGT CTTATGAAAG AATGGAGTTT GCTGTGTACT ACGAGTGCAA TGGACAGACG 
TACTGGGACA GCAACAGAGG CAAGAACTAT AGGATCATCC GGGCTGAGTT AAAATCTACC 
CAGGGAATGA CCAAGCCCCA CAGTGGACCG GATTTGGGAA TATCCTTTGA CCAGTTCGGA 
AGCCCTCGGT GTTCCTATGG TCTGTTTCCA GAGTGGCCAA GTTACTTAGG ATATGAAAAG 
CTAGGGCCCT ACTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PPP1R3B ( XM_006716253.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006716316.1 Homo sapiens protein phosphatase 1 regulatory subunit 3B (PPP1R3B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu25150
Clone ID Related Accession (Same CDS sequence)	NM_001201329.1 , XM_006716253.2 , NM_024607.3 , XM_017013835.1 , NM_024607.4 , NM_001201329.2 , XM_011543836.1 , XM_006716253.3
Accession Version	XM_006716253.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 858bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein phosphatase 1 regulatory subunit 3B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006716253.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGGCTG TGGACATCGA GTACAGATAC AACTGCATGG CTCCTTCCTT GCGCCAAGAG 
AGGTTTGCCT TTAAGATCTC ACCAAAGCCC AGCAAACCAC TGAGGCCTTG TATTCAGCTG 
AGCAGCAAGA ATGAAGCCAG TGGAATGGTG GCCCCGGCTG TCCAGGAGAA GAAGGTGAAA 
AAGCGGGTGT CCTTCGCAGA CAACCAGGGG CTGGCCCTGA CAATGGTCAA AGTGTTCTCG 
GAATTCGATG ACCCGCTAGA TATGCCATTC AACATCACCG AGCTCCTAGA CAACATTGTG 
AGCTTGACGA CAGCAGAGAG CGAGAGCTTT GTTCTGGATT TTTCCCAGCC CTCTGCAGAT 
TACTTAGACT TTAGAAATCG ACTTCAGGCC GACCACGTCT GCCTTGAGAA CTGTGTGCTC 
AAGGACAAGG CCATTGCAGG CACTGTGAAG GTTCAGAACC TCGCATTTGA GAAGACCGTG 
AAAATAAGGA TGACGTTCGA CACCTGGAAG AGCTACACAG ACTTTCCTTG TCAGTACGTG 
AAGGACACTT ATGCCGGTTC AGACAGGGAC ACGTTCTCCT TCGACATCAG CTTGCCCGAG 
AAGATTCAGT CTTATGAAAG AATGGAGTTT GCTGTGTACT ACGAGTGCAA TGGACAGACG 
TACTGGGACA GCAACAGAGG CAAGAACTAT AGGATCATCC GGGCTGAGTT AAAATCTACC 
CAGGGAATGA CCAAGCCCCA CAGTGGACCG GATTTGGGAA TATCCTTTGA CCAGTTCGGA 
AGCCCTCGGT GTTCCTATGG TCTGTTTCCA GAGTGGCCAA GTTACTTAGG ATATGAAAAG 
CTAGGGCCCT ACTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006716316.1
CDS	119..976
Translation	MMAVDIEYRYNCMAPSLRQERFAFKISPKPSKPLRPCIQLSSKNEASGMVAPAVQEKKVKKRVSFADNQGLALTMVKVFSEFDDPLDMPFNITELLDNIVSLTTAESESFVLDFSQPSADYLDFRNRLQADHVCLENCVLKDKAIAGTVKVQNLAFEKTVKIRMTFDTWKSYTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSYERMEFAVYYECNGQTYWDSNRGKNYRIIRAELKSTQGMTKPHSGPDLGISFDQFGSPRCSYGLFPEWPSYLGYEKLGPYY

Target ORF information:

RefSeq Version	XM_006716253.3
Organism	Homo sapiens(human)
Definition	Homo sapiens protein phosphatase 1 regulatory subunit 3B (PPP1R3B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006716253.3

ORF Insert Sequence:

ATGATGGCTG TGGACATCGA GTACAGATAC AACTGCATGG CTCCTTCCTT GCGCCAAGAG 
AGGTTTGCCT TTAAGATCTC ACCAAAGCCC AGCAAACCAC TGAGGCCTTG TATTCAGCTG 
AGCAGCAAGA ATGAAGCCAG TGGAATGGTG GCCCCGGCTG TCCAGGAGAA GAAGGTGAAA 
AAGCGGGTGT CCTTCGCAGA CAACCAGGGG CTGGCCCTGA CAATGGTCAA AGTGTTCTCG 
GAATTCGATG ACCCGCTAGA TATGCCATTC AACATCACCG AGCTCCTAGA CAACATTGTG 
AGCTTGACGA CAGCAGAGAG CGAGAGCTTT GTTCTGGATT TTTCCCAGCC CTCTGCAGAT 
TACTTAGACT TTAGAAATCG ACTTCAGGCC GACCACGTCT GCCTTGAGAA CTGTGTGCTC 
AAGGACAAGG CCATTGCAGG CACTGTGAAG GTTCAGAACC TCGCATTTGA GAAGACCGTG 
AAAATAAGGA TGACGTTCGA CACCTGGAAG AGCTACACAG ACTTTCCTTG TCAGTACGTG 
AAGGACACTT ATGCCGGTTC AGACAGGGAC ACGTTCTCCT TCGACATCAG CTTGCCCGAG 
AAGATTCAGT CTTATGAAAG AATGGAGTTT GCTGTGTACT ACGAGTGCAA TGGACAGACG 
TACTGGGACA GCAACAGAGG CAAGAACTAT AGGATCATCC GGGCTGAGTT AAAATCTACC 
CAGGGAATGA CCAAGCCCCA CAGTGGACCG GATTTGGGAA TATCCTTTGA CCAGTTCGGA 
AGCCCTCGGT GTTCCTATGG TCTGTTTCCA GAGTGGCCAA GTTACTTAGG ATATGAAAAG 
CTAGGGCCCT ACTACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Relationship between Genetic Variation at PPP1R3B and Liver Glycogen and Triglyceride Levels.
Hepatology (Baltimore, Md.)(2017 Dec)
Stender S,Smagris E,Lauridsen BK,Kofoed KF,Nordestgaard BG,Tybjaerg-Hansen A,Pennacchio LA,Dickel DE,Cohen JC,Hobbs HH

Association between PNPLA3 (rs738409), LYPLAL1 (rs12137855), PPP1R3B (rs4240624), GCKR (rs780094), and elevated transaminase levels in overweight/obese Mexican adults.
Molecular biology reports43(12)1359-1369(2016 Dec)
Flores YN,Vel?zquez-Cruz R,Ram?rez P,Ba?uelos M,Zhang ZF,Yee HF Jr,Chang SC,Canizales-Quinteros S,Quiterio M,Cabrera-Alvarez G,Pati?o N,Salmer?n J

GCKR and PPP1R3B identified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study.
Diabetic medicine : a journal of the British Diabetic Association33(7)968-75(2016 Jul)
Tin A,Balakrishnan P,Beaty TH,Boerwinkle E,Hoogeveen RC,Young JH,Kao WH

Loss of protein targeting to glycogen sensitizes human hepatocellular carcinoma cells towards glucose deprivation mediated oxidative stress and cell death.
Bioscience reports35(3)(2015 May)
Yang R,Zhang M,Gustafson AR,Wang E,Cole MP,Tooley CE,Cheng A

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PPP1R3B cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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