GCC1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GCC1
Entrez Gene ID	79571
Full Name	GRIP and coiled-coil domain containing 1
Synonyms	GCC1P,GCC88
General protein information	Preferred Names GRIP and coiled-coil domain containing 1 Names GRIP and coiled-coil domain-containing protein 1 golgi coiled-coil 1 golgi coiled-coil protein 1 peripheral membrane Golgi protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q32.1
Summary	The protein encoded by this gene is a peripheral membrane protein. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. It may play a role in the organization of trans-Golgi network subcompartment involved with membrane transport. [provided by RefSeq, Jul 2008].
Disorder MIM:	607418

mRNA and Protein(s)

mRNA	Protein	Name
NM_024523.6	NP_078799.2	GRIP and coiled-coil domain-containing protein 1
NM_024523.5	NP_078799.2	GRIP and coiled-coil domain-containing protein 1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	GCC1	XP_539388.2
Drosophila melanogaster (fruit fly)	CG10703	NP_650055.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012521	XP_313518.4
Homo sapiens (human)	GCC1	NP_078799.2
Pan troglodytes (chimpanzee)	GCC1	XP_519350.3
Danio rerio (zebrafish)	gcc1	NP_001003599.1
Bos taurus (cattle)	GCC1	NP_001192673.1
Gallus gallus (chicken)	GCC1	NP_001026760.1
	GCC1	XP_001089873.1
Mus musculus (house mouse)	Gcc1	NP_083176.3
Rattus norvegicus (Norway rat)	Gcc1	XP_006236298.1

Gene Ontology
Bibliography

Related articles in PubMed

An inter-species protein-protein interaction network across vast evolutionary distance.
Zhong Q, Pevzner SJ, Hao T, Wang Y, Mosca R, Menche J, Taipale M, Ta?an M, Fan C, Yang X, Haley P, Murray RR, Mer F, Gebreab F, Tam S, MacWilliams A, Dricot A, Reichert P, Santhanam B, Ghamsari L, Calderwood MA, Rolland T, Charloteaux B, Lindquist S, Barab?si AL, Hill DE, Aloy P, Cusick ME, Xia Y, Roth FP, Vidal M
Molecular systems biology12(4)865(2016 Apr)

Genome-wide association study of medication adherence in chronic diseases in the korean population.
Seo I, Suh SI, Suh MH, Baek WK
Genomics & informatics12(3)121-6(2014 Sep)

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
Cho YS, Chen CH, Hu C, Long J, Ong RT, Sim X, Takeuchi F, Wu Y, Go MJ, Yamauchi T, Chang YC, Kwak SH, Ma RC, Yamamoto K, Adair LS, Aung T, Cai Q, Chang LC, Chen YT, Gao Y, Hu FB, Kim HL, Kim S, Kim YJ, Lee JJ, Lee NR, Li Y, Liu JJ, Lu W, Nakamura J, Nakashima E, Ng DP, Tay WT, Tsai FJ, Wong TY, Yokota M, Zheng W, Zhang R, Wang C, So WY, Ohnaka K, Ikegami H, Hara K, Cho YM, Cho NH, Chang TJ, Bao Y, Hedman ?K, Morris AP, McCarthy MI, , , Takayanagi R, Park KS, Jia W, Chuang LM, Chan JC, Maeda S, Kadowaki T, Lee JY, Wu JY, Teo YY, Tai ES, Shu XO, Mohlke KL, Kato N, Han BG, Seielstad M
Nature genetics44(1)67-72(2011 Dec)

Next-generation sequencing to generate interactome datasets.
Yu H, Tardivo L, Tam S, Weiner E, Gebreab F, Fan C, Svrzikapa N, Hirozane-Kishikawa T, Rietman E, Yang X, Sahalie J, Salehi-Ashtiani K, Hao T, Cusick ME, Hill DE, Roth FP, Braun P, Vidal M
Nature methods8(6)478-80(2011 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

identified an essential role for GCC88 in the localization of TGN fusion machinery for transport from early endosomes to the trans-Golgi network
Title: The golgin GCC88 is required for efficient retrograde transport of cargo from the early endosomes to the trans-Golgi network.

The ability of the four mammalian GRIP domain proteins, p230, golgin-97, GCC88, and GCC185 to interact is reported.
Title: The trans-Golgi network GRIP-domain proteins form alpha-helical homodimers.

targeting to subcompartments of trans-Golgi network by GRIP domain
Title: GRIP domain-mediated targeting of two new coiled-coil proteins, GCC88 and GCC185, to subcompartments of the trans-Golgi network.

The following GCC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GCC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29879	NM_024523.6 Latest version!	Homo sapiens GRIP and coiled-coil domain containing 1 (GCC1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
View Old Accession Versions >>
OHu29879	NM_024523.5	Homo sapiens GRIP and coiled-coil domain containing 1 (GCC1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GCC1 ( NM_024523.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_078799.2 Homo sapiens GRIP and coiled-coil domain containing 1 (GCC1), mRNA.

Price & Availability↑

CloneID	OHu29879
Clone ID Related Accession (Same CDS sequence)	NM_024523.6 , NM_024523.5
Accession Version	NM_024523.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2328bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	GRIP and coiled-coil domain-containing protein 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC000357.1. On Nov 26, 2018 this sequence version replaced NM_024523.5. ##Evidence-Data-START## Transcript exon combination :: BC014100.2, SRR1803616.115256.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000321407.3/ ENSP00000318821.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGAAGT TTGGGATGAA TTTCGGGGGC GGCCCGAGCA AGAAGGACTT GCTGGAGACT 
ATAGAGACCC AGAAGAAGCA GCTTCTCCAG TACCAGGCAC GGCTCAAGGA TGTGGTCCGT 
GCCTATAAAA GCCTGCTGAA GGAGAAAGAG GCATTAGAGG CCAGCATCAA GGTGCTGTCG 
GTATCCCACG AGGCAGATGT GGGCCTCGCA GGTGTCCAGC TTCCAGGCCT CACCTTTCCT 
GACTCTGTGG ATGACCGGTG CTCCACTCAC AGCGAGGATA GCACTGGGAC CGCCACTAGC 
TTGGATACTG CGGCCAGTCT CACCAGCACC AAGGGTGAGT TTGGGGTAGA AGATGACAGA 
CCGGCCCGTG GACCACCACC TCCAAAGTCC GAAGAGGCCA GTTGGTCCGA GAGTGGCGTT 
AGCAGTAGCA GTGGGGATGG GCCATTTGCA GGTGGGGAGG TGGACAAAAG ACTGCACCAG 
CTGAAGACTC AGTTGGCTAC TTTGACCAGT TCTTTGGCTA CAGTCACTCA GGAGAAGTCC 
CGCATGGAGG CTTCTTACTT GGCTGACAAG AAAAAGATGA AACAGGACTT AGAGGATGCC 
AGTAACAAGG CGGAGGAGGA GAGGGCCCGC CTGGAGGGAG AATTGAAGGG GCTGCAGGAG 
CAAATAGCAG AAACCAAAGC CCGGCTTATC ACGCAGCAGC ATGATCGGGC CCAAGAGCAG 
AGTGACCATG CCTTGATGCT GCGTGAGCTC CAGAAGCTGC TGCAGGAGGA GAGGACCCAG 
CGCCAGGACT TGGAGCTTAG GTTAGAAGAG ACCCGAGAAG CCTTGGCAGG ACGAGCATAT 
GCAGCTGAAC AGATGGAAGG ATTTGAACTG CAGACCAAGC AGCTGACCCG TGAGGTGGAG 
GAGCTGAAAA GTGAACTGCA GGCCATTCGA GATGAGAAGA ATCAGCCAGA TCCCCGGCTG 
CAAGAACTTC AGGAAGAGGC TGCCCGCCTT AAGAGCCATT TCCAGGCTCA GTTACAGCAG 
GAAATGAGAA AGACAGCTCT TGCAGAGGAT CAACTCCGTC AGCAATCTCA GGTAGAAGAA 
CAGAGGGTGG CAGCCCTGGA GAATCAAATA TCCGAGGTGT CTGAGCTGCT AGGCACCTAC 
GAGAAAGCCA AGCAGAAGGA CCAGCTGGCC ATTCAGAAGC TGAAGGAGCG CATTCTGCAG 
CTGGACCTGG AGAACAAGAC ACTGGCTCTA GCAGCCTCCA GCAGGTCCCC TTTAGACAGC 
CATGGAGAGG AGTCCAGTCT GGATGTCAAT GTCCTGAAAG ATAAGATGGA GAAGCTGAAG 
AGGCTGCTGC AGGTTGCGGC CAGGAAAAGC CAGGTGACCC TGGATGTGGA GAAGCTCTGT 
GACCTGGAGA TAATGCCCAG CTCGGAGGCT GCTGATGGGG AGAAGGCTAC TGCACTCTAT 
TACCAACAGG AGCTGAAACA GCTGAAGGAA GAGTTTGAGA GGTACAAGAT GAGAGCCCAG 
GTTGTCCTCA AAAGCAAGAA TACCAAAGAT GGTAACCTGG GAAAGGAGCT GGAGGCAGCC 
CAGGAACAGC TTGCAGAGCT GAAGGAGAAG TATATTTCCC TGCGGCTCTC CTGCGAGGAG 
CTGGAGCACC AACACCAGCA GGAGGCTGAT GACTGGAAGC AGGAGCTGGC CCGGCTGCAG 
CAGCTCCACC GGCAGGAGCT GGAGCGGTGC CAGCTGGACT TCAGGGACCG CACACTGAAA 
CTGGAGGAGG AGCTGCACAA GCAGCGGGAT CGTGCCCTAG CTGTGCTCAC CGAGAAGGAC 
TTGGAACTGG AGCAACTGCG TTCTGTGGCC TTGGCCTCTG GGCTGCCAGG ACGCAGAAGT 
CCTGTGGGTG GTGGCGGTCC TGGGGACCCA GCTGACACAT CATCCTCTGA TAGCCTGACC 
CAAGCATTAC AACTTGCAGC GGCCAATGAG CCCACTTTCT TTCTGTACGC TGAGCAACTG 
GCCCGCAAGG AGGTGGAGAT CACATCACTG AGGAAGCAGA AGCACAGGCT GGAGGTCGAG 
GTGCATCAGC TGCAGGATCG GCTGCTGGAG GAGGGCGAAC GGCATCGTGA GGAGGTTGCA 
GCCCTGCAGA GCCACATCGA AAAGAACATC AGGGACCAGA GCAGGGAGGG AGCCAATCTG 
GAGTACCTCA AAAACATCAT CTACCGCTTC CTGACCTTAC CTGACTCCCT GGGCCGCCAG 
CAGACTCTCA CAGCCATACT GACTATCTTG CACTTCAGTC CAGAGGAGAA ACAAGTGATA 
ATGCGACTCC CAACCAGTGC CAGCTGGTGG CCTTCTGGCA AGAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078799.2
CDS	415..2742
Translation	MEKFGMNFGGGPSKKDLLETIETQKKQLLQYQARLKDVVRAYKSLLKEKEALEASIKVLSVSHEADVGLAGVQLPGLTFPDSVDDRCSTHSEDSTGTATSLDTAASLTSTKGEFGVEDDRPARGPPPPKSEEASWSESGVSSSSGDGPFAGGEVDKRLHQLKTQLATLTSSLATVTQEKSRMEASYLADKKKMKQDLEDASNKAEEERARLEGELKGLQEQIAETKARLITQQHDRAQEQSDHALMLRELQKLLQEERTQRQDLELRLEETREALAGRAYAAEQMEGFELQTKQLTREVEELKSELQAIRDEKNQPDPRLQELQEEAARLKSHFQAQLQQEMRKTALAEDQLRQQSQVEEQRVAALENQISEVSELLGTYEKAKQKDQLAIQKLKERILQLDLENKTLALAASSRSPLDSHGEESSLDVNVLKDKMEKLKRLLQVAARKSQVTLDVEKLCDLEIMPSSEAADGEKATALYYQQELKQLKEEFERYKMRAQVVLKSKNTKDGNLGKELEAAQEQLAELKEKYISLRLSCEELEHQHQQEADDWKQELARLQQLHRQELERCQLDFRDRTLKLEEELHKQRDRALAVLTEKDLELEQLRSVALASGLPGRRSPVGGGGPGDPADTSSSDSLTQALQLAAANEPTFFLYAEQLARKEVEITSLRKQKHRLEVEVHQLQDRLLEEGERHREEVAALQSHIEKNIRDQSREGANLEYLKNIIYRFLTLPDSLGRQQTLTAILTILHFSPEEKQVIMRLPTSASWWPSGKR

Target ORF information:

RefSeq Version	NM_024523.6
Organism	Homo sapiens(human)
Definition	Homo sapiens GRIP and coiled-coil domain containing 1 (GCC1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024523.6

ORF Insert Sequence:

ATGGAGAAGT TTGGGATGAA TTTCGGGGGC GGCCCGAGCA AGAAGGACTT GCTGGAGACT 
ATAGAGACCC AGAAGAAGCA GCTTCTCCAG TACCAGGCAC GGCTCAAGGA TGTGGTCCGT 
GCCTATAAAA GCCTGCTGAA GGAGAAAGAG GCATTAGAGG CCAGCATCAA GGTGCTGTCG 
GTATCCCACG AGGCAGATGT GGGCCTCGCA GGTGTCCAGC TTCCAGGCCT CACCTTTCCT 
GACTCTGTGG ATGACCGGTG CTCCACTCAC AGCGAGGATA GCACTGGGAC CGCCACTAGC 
TTGGATACTG CGGCCAGTCT CACCAGCACC AAGGGTGAGT TTGGGGTAGA AGATGACAGA 
CCGGCCCGTG GACCACCACC TCCAAAGTCC GAAGAGGCCA GTTGGTCCGA GAGTGGCGTT 
AGCAGTAGCA GTGGGGATGG GCCATTTGCA GGTGGGGAGG TGGACAAAAG ACTGCACCAG 
CTGAAGACTC AGTTGGCTAC TTTGACCAGT TCTTTGGCTA CAGTCACTCA GGAGAAGTCC 
CGCATGGAGG CTTCTTACTT GGCTGACAAG AAAAAGATGA AACAGGACTT AGAGGATGCC 
AGTAACAAGG CGGAGGAGGA GAGGGCCCGC CTGGAGGGAG AATTGAAGGG GCTGCAGGAG 
CAAATAGCAG AAACCAAAGC CCGGCTTATC ACGCAGCAGC ATGATCGGGC CCAAGAGCAG 
AGTGACCATG CCTTGATGCT GCGTGAGCTC CAGAAGCTGC TGCAGGAGGA GAGGACCCAG 
CGCCAGGACT TGGAGCTTAG GTTAGAAGAG ACCCGAGAAG CCTTGGCAGG ACGAGCATAT 
GCAGCTGAAC AGATGGAAGG ATTTGAACTG CAGACCAAGC AGCTGACCCG TGAGGTGGAG 
GAGCTGAAAA GTGAACTGCA GGCCATTCGA GATGAGAAGA ATCAGCCAGA TCCCCGGCTG 
CAAGAACTTC AGGAAGAGGC TGCCCGCCTT AAGAGCCATT TCCAGGCTCA GTTACAGCAG 
GAAATGAGAA AGACAGCTCT TGCAGAGGAT CAACTCCGTC AGCAATCTCA GGTAGAAGAA 
CAGAGGGTGG CAGCCCTGGA GAATCAAATA TCCGAGGTGT CTGAGCTGCT AGGCACCTAC 
GAGAAAGCCA AGCAGAAGGA CCAGCTGGCC ATTCAGAAGC TGAAGGAGCG CATTCTGCAG 
CTGGACCTGG AGAACAAGAC ACTGGCTCTA GCAGCCTCCA GCAGGTCCCC TTTAGACAGC 
CATGGAGAGG AGTCCAGTCT GGATGTCAAT GTCCTGAAAG ATAAGATGGA GAAGCTGAAG 
AGGCTGCTGC AGGTTGCGGC CAGGAAAAGC CAGGTGACCC TGGATGTGGA GAAGCTCTGT 
GACCTGGAGA TAATGCCCAG CTCGGAGGCT GCTGATGGGG AGAAGGCTAC TGCACTCTAT 
TACCAACAGG AGCTGAAACA GCTGAAGGAA GAGTTTGAGA GGTACAAGAT GAGAGCCCAG 
GTTGTCCTCA AAAGCAAGAA TACCAAAGAT GGTAACCTGG GAAAGGAGCT GGAGGCAGCC 
CAGGAACAGC TTGCAGAGCT GAAGGAGAAG TATATTTCCC TGCGGCTCTC CTGCGAGGAG 
CTGGAGCACC AACACCAGCA GGAGGCTGAT GACTGGAAGC AGGAGCTGGC CCGGCTGCAG 
CAGCTCCACC GGCAGGAGCT GGAGCGGTGC CAGCTGGACT TCAGGGACCG CACACTGAAA 
CTGGAGGAGG AGCTGCACAA GCAGCGGGAT CGTGCCCTAG CTGTGCTCAC CGAGAAGGAC 
TTGGAACTGG AGCAACTGCG TTCTGTGGCC TTGGCCTCTG GGCTGCCAGG ACGCAGAAGT 
CCTGTGGGTG GTGGCGGTCC TGGGGACCCA GCTGACACAT CATCCTCTGA TAGCCTGACC 
CAAGCATTAC AACTTGCAGC GGCCAATGAG CCCACTTTCT TTCTGTACGC TGAGCAACTG 
GCCCGCAAGG AGGTGGAGAT CACATCACTG AGGAAGCAGA AGCACAGGCT GGAGGTCGAG 
GTGCATCAGC TGCAGGATCG GCTGCTGGAG GAGGGCGAAC GGCATCGTGA GGAGGTTGCA 
GCCCTGCAGA GCCACATCGA AAAGAACATC AGGGACCAGA GCAGGGAGGG AGCCAATCTG 
GAGTACCTCA AAAACATCAT CTACCGCTTC CTGACCTTAC CTGACTCCCT GGGCCGCCAG 
CAGACTCTCA CAGCCATACT GACTATCTTG CACTTCAGTC CAGAGGAGAA ACAAGTGATA 
ATGCGACTCC CAACCAGTGC CAGCTGGTGG CCTTCTGGCA AGAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GCC1 ( NM_024523.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_078799.2 Homo sapiens GRIP and coiled-coil domain containing 1 (GCC1), mRNA.

Price & Availability↑

CloneID	OHu29879
Clone ID Related Accession (Same CDS sequence)	NM_024523.6 , NM_024523.5
Accession Version	NM_024523.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2328bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	GRIP and coiled-coil domain-containing protein 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC014100.2. On Aug 27, 2003 this sequence version replaced NM_024523.4. ##Evidence-Data-START## Transcript exon combination :: BC014100.2, SRR1803616.115256.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGAAGT TTGGGATGAA TTTCGGGGGC GGCCCGAGCA AGAAGGACTT GCTGGAGACT 
ATAGAGACCC AGAAGAAGCA GCTTCTCCAG TACCAGGCAC GGCTCAAGGA TGTGGTCCGT 
GCCTATAAAA GCCTGCTGAA GGAGAAAGAG GCATTAGAGG CCAGCATCAA GGTGCTGTCG 
GTATCCCACG AGGCAGATGT GGGCCTCGCA GGTGTCCAGC TTCCAGGCCT CACCTTTCCT 
GACTCTGTGG ATGACCGGTG CTCCACTCAC AGCGAGGATA GCACTGGGAC CGCCACTAGC 
TTGGATACTG CGGCCAGTCT CACCAGCACC AAGGGTGAGT TTGGGGTAGA AGATGACAGA 
CCGGCCCGTG GACCACCACC TCCAAAGTCC GAAGAGGCCA GTTGGTCCGA GAGTGGCGTT 
AGCAGTAGCA GTGGGGATGG GCCATTTGCA GGTGGGGAGG TGGACAAAAG ACTGCACCAG 
CTGAAGACTC AGTTGGCTAC TTTGACCAGT TCTTTGGCTA CAGTCACTCA GGAGAAGTCC 
CGCATGGAGG CTTCTTACTT GGCTGACAAG AAAAAGATGA AACAGGACTT AGAGGATGCC 
AGTAACAAGG CGGAGGAGGA GAGGGCCCGC CTGGAGGGAG AATTGAAGGG GCTGCAGGAG 
CAAATAGCAG AAACCAAAGC CCGGCTTATC ACGCAGCAGC ATGATCGGGC CCAAGAGCAG 
AGTGACCATG CCTTGATGCT GCGTGAGCTC CAGAAGCTGC TGCAGGAGGA GAGGACCCAG 
CGCCAGGACT TGGAGCTTAG GTTAGAAGAG ACCCGAGAAG CCTTGGCAGG ACGAGCATAT 
GCAGCTGAAC AGATGGAAGG ATTTGAACTG CAGACCAAGC AGCTGACCCG TGAGGTGGAG 
GAGCTGAAAA GTGAACTGCA GGCCATTCGA GATGAGAAGA ATCAGCCAGA TCCCCGGCTG 
CAAGAACTTC AGGAAGAGGC TGCCCGCCTT AAGAGCCATT TCCAGGCTCA GTTACAGCAG 
GAAATGAGAA AGACAGCTCT TGCAGAGGAT CAACTCCGTC AGCAATCTCA GGTAGAAGAA 
CAGAGGGTGG CAGCCCTGGA GAATCAAATA TCCGAGGTGT CTGAGCTGCT AGGCACCTAC 
GAGAAAGCCA AGCAGAAGGA CCAGCTGGCC ATTCAGAAGC TGAAGGAGCG CATTCTGCAG 
CTGGACCTGG AGAACAAGAC ACTGGCTCTA GCAGCCTCCA GCAGGTCCCC TTTAGACAGC 
CATGGAGAGG AGTCCAGTCT GGATGTCAAT GTCCTGAAAG ATAAGATGGA GAAGCTGAAG 
AGGCTGCTGC AGGTTGCGGC CAGGAAAAGC CAGGTGACCC TGGATGTGGA GAAGCTCTGT 
GACCTGGAGA TAATGCCCAG CTCGGAGGCT GCTGATGGGG AGAAGGCTAC TGCACTCTAT 
TACCAACAGG AGCTGAAACA GCTGAAGGAA GAGTTTGAGA GGTACAAGAT GAGAGCCCAG 
GTTGTCCTCA AAAGCAAGAA TACCAAAGAT GGTAACCTGG GAAAGGAGCT GGAGGCAGCC 
CAGGAACAGC TTGCAGAGCT GAAGGAGAAG TATATTTCCC TGCGGCTCTC CTGCGAGGAG 
CTGGAGCACC AACACCAGCA GGAGGCTGAT GACTGGAAGC AGGAGCTGGC CCGGCTGCAG 
CAGCTCCACC GGCAGGAGCT GGAGCGGTGC CAGCTGGACT TCAGGGACCG CACACTGAAA 
CTGGAGGAGG AGCTGCACAA GCAGCGGGAT CGTGCCCTAG CTGTGCTCAC CGAGAAGGAC 
TTGGAACTGG AGCAACTGCG TTCTGTGGCC TTGGCCTCTG GGCTGCCAGG ACGCAGAAGT 
CCTGTGGGTG GTGGCGGTCC TGGGGACCCA GCTGACACAT CATCCTCTGA TAGCCTGACC 
CAAGCATTAC AACTTGCAGC GGCCAATGAG CCCACTTTCT TTCTGTACGC TGAGCAACTG 
GCCCGCAAGG AGGTGGAGAT CACATCACTG AGGAAGCAGA AGCACAGGCT GGAGGTCGAG 
GTGCATCAGC TGCAGGATCG GCTGCTGGAG GAGGGCGAAC GGCATCGTGA GGAGGTTGCA 
GCCCTGCAGA GCCACATCGA AAAGAACATC AGGGACCAGA GCAGGGAGGG AGCCAATCTG 
GAGTACCTCA AAAACATCAT CTACCGCTTC CTGACCTTAC CTGACTCCCT GGGCCGCCAG 
CAGACTCTCA CAGCCATACT GACTATCTTG CACTTCAGTC CAGAGGAGAA ACAAGTGATA 
ATGCGACTCC CAACCAGTGC CAGCTGGTGG CCTTCTGGCA AGAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078799.2
CDS	419..2746
Translation	MEKFGMNFGGGPSKKDLLETIETQKKQLLQYQARLKDVVRAYKSLLKEKEALEASIKVLSVSHEADVGLAGVQLPGLTFPDSVDDRCSTHSEDSTGTATSLDTAASLTSTKGEFGVEDDRPARGPPPPKSEEASWSESGVSSSSGDGPFAGGEVDKRLHQLKTQLATLTSSLATVTQEKSRMEASYLADKKKMKQDLEDASNKAEEERARLEGELKGLQEQIAETKARLITQQHDRAQEQSDHALMLRELQKLLQEERTQRQDLELRLEETREALAGRAYAAEQMEGFELQTKQLTREVEELKSELQAIRDEKNQPDPRLQELQEEAARLKSHFQAQLQQEMRKTALAEDQLRQQSQVEEQRVAALENQISEVSELLGTYEKAKQKDQLAIQKLKERILQLDLENKTLALAASSRSPLDSHGEESSLDVNVLKDKMEKLKRLLQVAARKSQVTLDVEKLCDLEIMPSSEAADGEKATALYYQQELKQLKEEFERYKMRAQVVLKSKNTKDGNLGKELEAAQEQLAELKEKYISLRLSCEELEHQHQQEADDWKQELARLQQLHRQELERCQLDFRDRTLKLEEELHKQRDRALAVLTEKDLELEQLRSVALASGLPGRRSPVGGGGPGDPADTSSSDSLTQALQLAAANEPTFFLYAEQLARKEVEITSLRKQKHRLEVEVHQLQDRLLEEGERHREEVAALQSHIEKNIRDQSREGANLEYLKNIIYRFLTLPDSLGRQQTLTAILTILHFSPEEKQVIMRLPTSASWWPSGKR

Target ORF information:

RefSeq Version	NM_024523.5
Organism	Homo sapiens(human)
Definition	Homo sapiens GRIP and coiled-coil domain containing 1 (GCC1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024523.5

ORF Insert Sequence:

ATGGAGAAGT TTGGGATGAA TTTCGGGGGC GGCCCGAGCA AGAAGGACTT GCTGGAGACT 
ATAGAGACCC AGAAGAAGCA GCTTCTCCAG TACCAGGCAC GGCTCAAGGA TGTGGTCCGT 
GCCTATAAAA GCCTGCTGAA GGAGAAAGAG GCATTAGAGG CCAGCATCAA GGTGCTGTCG 
GTATCCCACG AGGCAGATGT GGGCCTCGCA GGTGTCCAGC TTCCAGGCCT CACCTTTCCT 
GACTCTGTGG ATGACCGGTG CTCCACTCAC AGCGAGGATA GCACTGGGAC CGCCACTAGC 
TTGGATACTG CGGCCAGTCT CACCAGCACC AAGGGTGAGT TTGGGGTAGA AGATGACAGA 
CCGGCCCGTG GACCACCACC TCCAAAGTCC GAAGAGGCCA GTTGGTCCGA GAGTGGCGTT 
AGCAGTAGCA GTGGGGATGG GCCATTTGCA GGTGGGGAGG TGGACAAAAG ACTGCACCAG 
CTGAAGACTC AGTTGGCTAC TTTGACCAGT TCTTTGGCTA CAGTCACTCA GGAGAAGTCC 
CGCATGGAGG CTTCTTACTT GGCTGACAAG AAAAAGATGA AACAGGACTT AGAGGATGCC 
AGTAACAAGG CGGAGGAGGA GAGGGCCCGC CTGGAGGGAG AATTGAAGGG GCTGCAGGAG 
CAAATAGCAG AAACCAAAGC CCGGCTTATC ACGCAGCAGC ATGATCGGGC CCAAGAGCAG 
AGTGACCATG CCTTGATGCT GCGTGAGCTC CAGAAGCTGC TGCAGGAGGA GAGGACCCAG 
CGCCAGGACT TGGAGCTTAG GTTAGAAGAG ACCCGAGAAG CCTTGGCAGG ACGAGCATAT 
GCAGCTGAAC AGATGGAAGG ATTTGAACTG CAGACCAAGC AGCTGACCCG TGAGGTGGAG 
GAGCTGAAAA GTGAACTGCA GGCCATTCGA GATGAGAAGA ATCAGCCAGA TCCCCGGCTG 
CAAGAACTTC AGGAAGAGGC TGCCCGCCTT AAGAGCCATT TCCAGGCTCA GTTACAGCAG 
GAAATGAGAA AGACAGCTCT TGCAGAGGAT CAACTCCGTC AGCAATCTCA GGTAGAAGAA 
CAGAGGGTGG CAGCCCTGGA GAATCAAATA TCCGAGGTGT CTGAGCTGCT AGGCACCTAC 
GAGAAAGCCA AGCAGAAGGA CCAGCTGGCC ATTCAGAAGC TGAAGGAGCG CATTCTGCAG 
CTGGACCTGG AGAACAAGAC ACTGGCTCTA GCAGCCTCCA GCAGGTCCCC TTTAGACAGC 
CATGGAGAGG AGTCCAGTCT GGATGTCAAT GTCCTGAAAG ATAAGATGGA GAAGCTGAAG 
AGGCTGCTGC AGGTTGCGGC CAGGAAAAGC CAGGTGACCC TGGATGTGGA GAAGCTCTGT 
GACCTGGAGA TAATGCCCAG CTCGGAGGCT GCTGATGGGG AGAAGGCTAC TGCACTCTAT 
TACCAACAGG AGCTGAAACA GCTGAAGGAA GAGTTTGAGA GGTACAAGAT GAGAGCCCAG 
GTTGTCCTCA AAAGCAAGAA TACCAAAGAT GGTAACCTGG GAAAGGAGCT GGAGGCAGCC 
CAGGAACAGC TTGCAGAGCT GAAGGAGAAG TATATTTCCC TGCGGCTCTC CTGCGAGGAG 
CTGGAGCACC AACACCAGCA GGAGGCTGAT GACTGGAAGC AGGAGCTGGC CCGGCTGCAG 
CAGCTCCACC GGCAGGAGCT GGAGCGGTGC CAGCTGGACT TCAGGGACCG CACACTGAAA 
CTGGAGGAGG AGCTGCACAA GCAGCGGGAT CGTGCCCTAG CTGTGCTCAC CGAGAAGGAC 
TTGGAACTGG AGCAACTGCG TTCTGTGGCC TTGGCCTCTG GGCTGCCAGG ACGCAGAAGT 
CCTGTGGGTG GTGGCGGTCC TGGGGACCCA GCTGACACAT CATCCTCTGA TAGCCTGACC 
CAAGCATTAC AACTTGCAGC GGCCAATGAG CCCACTTTCT TTCTGTACGC TGAGCAACTG 
GCCCGCAAGG AGGTGGAGAT CACATCACTG AGGAAGCAGA AGCACAGGCT GGAGGTCGAG 
GTGCATCAGC TGCAGGATCG GCTGCTGGAG GAGGGCGAAC GGCATCGTGA GGAGGTTGCA 
GCCCTGCAGA GCCACATCGA AAAGAACATC AGGGACCAGA GCAGGGAGGG AGCCAATCTG 
GAGTACCTCA AAAACATCAT CTACCGCTTC CTGACCTTAC CTGACTCCCT GGGCCGCCAG 
CAGACTCTCA CAGCCATACT GACTATCTTG CACTTCAGTC CAGAGGAGAA ACAAGTGATA 
ATGCGACTCC CAACCAGTGC CAGCTGGTGG CCTTCTGGCA AGAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

An inter-species protein-protein interaction network across vast evolutionary distance.
Molecular systems biology12(4)865(2016 Apr)
Zhong Q,Pevzner SJ,Hao T,Wang Y,Mosca R,Menche J,Taipale M,Ta?an M,Fan C,Yang X,Haley P,Murray RR,Mer F,Gebreab F,Tam S,MacWilliams A,Dricot A,Reichert P,Santhanam B,Ghamsari L,Calderwood MA,Rolland T,Charloteaux B,Lindquist S,Barab?si AL,Hill DE,Aloy P,Cusick ME,Xia Y,Roth FP,Vidal M

Genome-wide association study of medication adherence in chronic diseases in the korean population.
Genomics & informatics12(3)121-6(2014 Sep)
Seo I,Suh SI,Suh MH,Baek WK

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
Nature genetics44(1)67-72(2011 Dec)
Cho YS,Chen CH,Hu C,Long J,Ong RT,Sim X,Takeuchi F,Wu Y,Go MJ,Yamauchi T,Chang YC,Kwak SH,Ma RC,Yamamoto K,Adair LS,Aung T,Cai Q,Chang LC,Chen YT,Gao Y,Hu FB,Kim HL,Kim S,Kim YJ,Lee JJ,Lee NR,Li Y,Liu JJ,Lu W,Nakamura J,Nakashima E,Ng DP,Tay WT,Tsai FJ,Wong TY,Yokota M,Zheng W,Zhang R,Wang C,So WY,Ohnaka K,Ikegami H,Hara K,Cho YM,Cho NH,Chang TJ,Bao Y,Hedman ?K,Morris AP,McCarthy MI,,,Takayanagi R,Park KS,Jia W,Chuang LM,Chan JC,Maeda S,Kadowaki T,Lee JY,Wu JY,Teo YY,Tai ES,Shu XO,Mohlke KL,Kato N,Han BG,Seielstad M

Next-generation sequencing to generate interactome datasets.
Nature methods8(6)478-80(2011 Jun)
Yu H,Tardivo L,Tam S,Weiner E,Gebreab F,Fan C,Svrzikapa N,Hirozane-Kishikawa T,Rietman E,Yang X,Sahalie J,Salehi-Ashtiani K,Hao T,Cusick ME,Hill DE,Roth FP,Braun P,Vidal M

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GCC1 cDNA ORF clone, Homo sapiens(human)

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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