ZNF735 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ZNF735
Entrez Gene ID	730291
Full Name	zinc finger protein 735
Synonyms	ZNF735P
General protein information	Preferred Names zinc finger protein 735 Names putative zinc finger protein 735 zinc finger protein 735 pseudogene
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q11.21
Summary	This gene encodes a kruppel-associated box-containing zinc finger protein (KRAB-ZFP). The encoded protein contains an N-terminal kruppel-associated box (KRAB) domain and nine C-terminal C2H2-type zinc finger domains. The KRAB-ZFPs represent the largest family of mammalian transcriptional repressors, which function through the recruitment of the nuclear co-factor KRAB-Associated Protein 1 (KAP1), to engage histone modifiers and induce heterochromatin formation. [provided by RefSeq, Jul 2017].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001159524.1	NP_001152996.1	putative zinc finger protein 735

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LOC100611103	XP_003318479.1
	ZNF735	XP_001100432.2
Homo sapiens (human)	ZNF735	NP_001152996.1

Gene Ontology
Bibliography

Related articles in PubMed

KRAB zinc-finger proteins contribute to the evolution of gene regulatory networks.
Imbeault M, Helleboid PY, Trono D
Nature543(7646)550-554(2017 03)

Evolution of KRAB-containing zinc finger proteins and their roles in species evolution.
Wang J, Wang J, Tian CY
Yi chuan = Hereditas38(11)971-978(2016 11)

Zinc fingers function cooperatively with KRAB domain for nuclear localization of KRAB-containing zinc finger proteins.
Wang W, Cai J, Lin Y, Liu Z, Ren Q, Hu L, Huang Z, Guo M, Li W
PloS one9(3)e92155(2014)

Cys2His2 zinc finger protein family: classification, functions, and major members.
Razin SV, Borunova VV, Maksimenko OG, Kantidze OL
Biochemistry. Biokhimiia77(3)217-26(2012 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

The following ZNF735 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ZNF735 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu14825	NM_001159524.1 Latest version!	Homo sapiens zinc finger protein 735 (ZNF735), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$174.50-$244.30 $349.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ZNF735 ( NM_001159524.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001152996.1 Homo sapiens zinc finger protein 735 (ZNF735), mRNA.

Price & Availability↑

CloneID	OHu14825
Clone ID Related Accession (Same CDS sequence)	NM_001159524.1
Accession Version	NM_001159524.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1239bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-30
Organism	Homo sapiens(human)
Product	putative zinc finger protein 735
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC104094.4 and AC073270.6. On or before Jul 18, 2009 this sequence version replaced XM_001719618.1, XM_001719651.1, XM_002344353.1, XM_002346880.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGGCTAAAA GACCGGGACC CCCTGGAAGC CGAGAAATGG GACTGTTGAC ATTCAGAGAC 
ATAGCTATAG AATTCTCTCT GGCGGAGTGG CAATGCCTGG ATCATGCTCA GCAGAATTTA 
TATAGAGATG TGATGTTAGA GAACTACAGA AACCTGTTCT CCCTGGGTAT GACTGTCTCT 
AAGCCAGACT TGATCGCCTG TCTGGAGCAA AATAAAGAGC CCCAGAATAT AAAGAGAAAT 
GAGATGGCAG CCAAACACCC AGTTACATGT TCTCATTTCA ACCAAGACCT TCAGCCAGAG 
CAGAGCATAA AAGATTCACT CCAAAAAGTA ATACCAAGAA CATATGGAAA ATGTGGACAT 
GAGAATTTAC AATTAAAAAA ATGTTGTAAA AGAGTAGATG AGTGTGAGGT GCACAAAGGA 
GGTTATAATG ACCTTAACCA ATGTTTGTCA AATACCCAAA ACAAAATATT TCAGACTCAT 
AAATGTGTCA AAGTCTTCAG TAAATTTTCA AATTCCAATA GACACAATGC AAGATATACT 
GGAAAGAAAC ATTTGAAATG TAAAAAATAT GGCAAATCAT TTTGCATGTT TTCACACCTA 
AATCAACATC AGATAATTCA TACTAAGGAG AAGTCCTACA AATGTGAAGA ATGTGGCAAA 
TCCTTTAACC ACTCCTCAAG CGGTACTACA CATAAAAGAA TTCTTACTGG AGAGAAACCC 
TACAGATGTG AGGAATGTGG CAAAGCCTTT AGGTGGCCCT CAAACCTTAC TAGACATAAG 
AGAATTCACA CTGGAGAGAA ACCCTACGCA TGTGAAGAAT GTGGCCAAGC CTTTAGGCGC 
TCCTCAACAC TTACTAACCA CAAGAGAATT CATACTGGAG AGAGACCCTA CAAATGTGAA 
GAATGTGGCA AAGCCTTTAG CGTATCCTCA GCCCTCATTT ACCACAAGAG AATTCATACT 
GGAGAGAAAC CCTACACATG TGAAGAATGT GGCAAAGCCT TTAACTGCTC CTCGACTCTT 
AAGACACATA AGATAATTCA TACTGGAGAG AAACCCTACA CATGTGAAGA ATGTGGCAGA 
ACCTTTAACT GCTCCTCAAC TGTAAAGGCA CATAAGAGAA TTCATACTGG AGAGAAACCA 
TACAAATGTG AAGAATGTGA CAAAGCTTTT AAGTGGCATT CAAGTCTTGC TAAACATAAG 
ATAATTCACA CTGGAGAGAA ACCCTACAAA TGTAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001152996.1
CDS	1..1239
Translation	MAKRPGPPGSREMGLLTFRDIAIEFSLAEWQCLDHAQQNLYRDVMLENYRNLFSLGMTVSKPDLIACLEQNKEPQNIKRNEMAAKHPVTCSHFNQDLQPEQSIKDSLQKVIPRTYGKCGHENLQLKKCCKRVDECEVHKGGYNDLNQCLSNTQNKIFQTHKCVKVFSKFSNSNRHNARYTGKKHLKCKKYGKSFCMFSHLNQHQIIHTKEKSYKCEECGKSFNHSSSGTTHKRILTGEKPYRCEECGKAFRWPSNLTRHKRIHTGEKPYACEECGQAFRRSSTLTNHKRIHTGERPYKCEECGKAFSVSSALIYHKRIHTGEKPYTCEECGKAFNCSSTLKTHKIIHTGEKPYTCEECGRTFNCSSTVKAHKRIHTGEKPYKCEECDKAFKWHSSLAKHKIIHTGEKPYKCK

Target ORF information:

RefSeq Version	NM_001159524.1
Organism	Homo sapiens(human)
Definition	Homo sapiens zinc finger protein 735 (ZNF735), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001159524.1

ORF Insert Sequence:

ATGGCTAAAA GACCGGGACC CCCTGGAAGC CGAGAAATGG GACTGTTGAC ATTCAGAGAC 
ATAGCTATAG AATTCTCTCT GGCGGAGTGG CAATGCCTGG ATCATGCTCA GCAGAATTTA 
TATAGAGATG TGATGTTAGA GAACTACAGA AACCTGTTCT CCCTGGGTAT GACTGTCTCT 
AAGCCAGACT TGATCGCCTG TCTGGAGCAA AATAAAGAGC CCCAGAATAT AAAGAGAAAT 
GAGATGGCAG CCAAACACCC AGTTACATGT TCTCATTTCA ACCAAGACCT TCAGCCAGAG 
CAGAGCATAA AAGATTCACT CCAAAAAGTA ATACCAAGAA CATATGGAAA ATGTGGACAT 
GAGAATTTAC AATTAAAAAA ATGTTGTAAA AGAGTAGATG AGTGTGAGGT GCACAAAGGA 
GGTTATAATG ACCTTAACCA ATGTTTGTCA AATACCCAAA ACAAAATATT TCAGACTCAT 
AAATGTGTCA AAGTCTTCAG TAAATTTTCA AATTCCAATA GACACAATGC AAGATATACT 
GGAAAGAAAC ATTTGAAATG TAAAAAATAT GGCAAATCAT TTTGCATGTT TTCACACCTA 
AATCAACATC AGATAATTCA TACTAAGGAG AAGTCCTACA AATGTGAAGA ATGTGGCAAA 
TCCTTTAACC ACTCCTCAAG CGGTACTACA CATAAAAGAA TTCTTACTGG AGAGAAACCC 
TACAGATGTG AGGAATGTGG CAAAGCCTTT AGGTGGCCCT CAAACCTTAC TAGACATAAG 
AGAATTCACA CTGGAGAGAA ACCCTACGCA TGTGAAGAAT GTGGCCAAGC CTTTAGGCGC 
TCCTCAACAC TTACTAACCA CAAGAGAATT CATACTGGAG AGAGACCCTA CAAATGTGAA 
GAATGTGGCA AAGCCTTTAG CGTATCCTCA GCCCTCATTT ACCACAAGAG AATTCATACT 
GGAGAGAAAC CCTACACATG TGAAGAATGT GGCAAAGCCT TTAACTGCTC CTCGACTCTT 
AAGACACATA AGATAATTCA TACTGGAGAG AAACCCTACA CATGTGAAGA ATGTGGCAGA 
ACCTTTAACT GCTCCTCAAC TGTAAAGGCA CATAAGAGAA TTCATACTGG AGAGAAACCA 
TACAAATGTG AAGAATGTGA CAAAGCTTTT AAGTGGCATT CAAGTCTTGC TAAACATAAG 
ATAATTCACA CTGGAGAGAA ACCCTACAAA TGTAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

KRAB zinc-finger proteins contribute to the evolution of gene regulatory networks.
Nature543(7646)550-554(2017 03)
Imbeault M,Helleboid PY,Trono D

Evolution of KRAB-containing zinc finger proteins and their roles in species evolution.
Yi chuan = Hereditas38(11)971-978(2016 11)
Wang J,Wang J,Tian CY

Zinc fingers function cooperatively with KRAB domain for nuclear localization of KRAB-containing zinc finger proteins.
PloS one9(3)e92155(2014)
Wang W,Cai J,Lin Y,Liu Z,Ren Q,Hu L,Huang Z,Guo M,Li W

Cys2His2 zinc finger protein family: classification, functions, and major members.
Biochemistry. Biokhimiia77(3)217-26(2012 Mar)
Razin SV,Borunova VV,Maksimenko OG,Kantidze OL

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ZNF735 cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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