SLC15A1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SLC15A1
Entrez Gene ID	6564
Full Name	solute carrier family 15 member 1
Synonyms	HPECT1,HPEPT1,PEPT1
General protein information	Preferred Names solute carrier family 15 member 1 Names solute carrier family 15 member 1 Caco-2 oligopeptide transporter intestinal H+/peptide cotransporter macrophage oligopeptide transporter PEPT1 oligopeptide transporter, small intestine isoform peptide transporter 1 solute carrier family 15 (oligopeptide transporter), member 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 13 Map Location: 13q32.2-q32.3
Summary	This gene encodes an intestinal hydrogen peptide cotransporter that is a member of the solute carrier family 15. The encoded protein is localized to the brush border membrane of the intestinal epithelium and mediates the uptake of di- and tripeptides from the lumen into the enterocytes. This protein plays an important role in the uptake and digestion of dietary proteins. This protein also facilitates the absorption of numerous peptidomimetic drugs. [provided by RefSeq, Apr 2010].
Disorder MIM:	600544

mRNA and Protein(s)

mRNA	Protein	Name
NM_005073.3	NP_005064.1	solute carrier family 15 member 1
NM_005073.4	NP_005064.1	solute carrier family 15 member 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SLC15A1	XP_522705.3
Canis lupus familiaris (dog)	SLC15A1	NP_001003036.1
Schizosaccharomyces pombe (fission yeast)	SPBC13A2.04c	NP_596417.1
	SLC15A1	NP_001028071.1
Danio rerio (zebrafish)	slc15a1b	NP_932330.1
Saccharomyces cerevisiae (baker's yeast)	PTR2	NP_013019.1
Oryza sativa (rice)	Os03g0719900	NP_001051098.1
Rattus norvegicus (Norway rat)	Slc15a1	NP_476462.1
Gallus gallus (chicken)	SLC15A1	NP_989696.1
Danio rerio (zebrafish)	slc15a1a	XP_001919914.3
Caenorhabditis elegans (roundworm)	pept-1	NP_509087.1
Xenopus tropicalis (tropical clawed frog)	slc15a1	XP_002935692.2
Bos taurus (cattle)	SLC15A1	NP_001092848.1
Drosophila melanogaster (fruit fly)	CG2930	NP_788857.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010383	XP_311562.3
Kluyveromyces lactis	KLLA0E12915g	XP_454532.1
Homo sapiens (human)	SLC15A1	NP_005064.1
Mus musculus (house mouse)	Slc15a1	NP_444309.2
Caenorhabditis elegans (roundworm)	pept-2	NP_502002.1
Arabidopsis thaliana (thale cress)	PTR2	NP_178313.1

Gene Ontology
Bibliography

Related articles in PubMed

Regulation profile of the intestinal peptide transporter 1 (PepT1).
Wang CY, Liu S, Xie XN, Tan ZR
Drug design, development and therapy113511-3517(2017)

Human Intestinal PEPT1 Transporter Expression and Localization in Preterm and Term Infants.
Mooij MG, de Koning BE, Lindenbergh-Kortleve DJ, Simons-Oosterhuis Y, van Groen BD, Tibboel D, Samsom JN, de Wildt SN
Drug metabolism and disposition: the biological fate of chemicals44(7)1014-9(2016 Jul)

Species differences in the pharmacokinetics of cefadroxil as determined in wildtype and humanized PepT1 mice.
Hu Y, Smith DE
Biochemical pharmacology10781-90(2016 May)

A new target ligand Ser-Glu for PEPT1-overexpressing cancer imaging.
Dai T, Li N, Zhang L, Zhang Y, Liu Q
International journal of nanomedicine11203-12(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data (including data from studies in transgenic/knockout mice) suggest human PEPT1 and mouse PepT1 exhibit different affinities for antibiotic cefadroxil; these differences may account for species differences in intestinal absorption of cefadroxil.
Title: Species differences in the pharmacokinetics of cefadroxil as determined in wildtype and humanized PepT1 mice.

PEPT1 overexpression is associated with pancreatic cancer.
Title: A new target ligand Ser-Glu for PEPT1-overexpressing cancer imaging.

miRNA-193a-3p can target colonic PepT1 and reduce intestinal inflammation.
Title: MicroRNA-193a-3p Reduces Intestinal Inflammation in Response to Microbiota via Down-regulation of Colonic PepT1.

OSR1 has the capacity to downregulate the peptide transporters PEPT1 and PEPT2 by decreasing the carrier protein abundance in the cell membrane
Title: Downregulation of peptide transporters PEPT1 and PEPT2 by oxidative stress responsive kinase OSR1.

Phe-Psi-Ala is a high-affinity, metabolically stable, non-radioactive probe for PEPT1.
Title: Evaluation of a thiodipeptide, L-phenylalanyl-?[CS-N]-L-alanine, as a novel probe for peptide transporter 1.

The following SLC15A1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC15A1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19511	NM_005073.4 Latest version!	Homo sapiens solute carrier family 15 member 1 (SLC15A1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu19511	NM_005073.3	Homo sapiens solute carrier family 15 member 1 (SLC15A1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SLC15A1 ( NM_005073.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005064.1 Homo sapiens solute carrier family 15 member 1 (SLC15A1), mRNA.

Price & Availability↑

CloneID	OHu19511
Clone ID Related Accession (Same CDS sequence)	NM_005073.3 , NM_005073.4
Accession Version	NM_005073.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2127bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-06
Organism	Homo sapiens(human)
Product	solute carrier family 15 member 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL708816.1, U13173.1, CU445953.1, BC096329.3 and AW449979.1. This sequence is a reference standard in the RefSeqGene project. On Jan 24, 2009 this sequence version replaced NM_005073.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U21936.1, BC096329.3 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAATGT CCAAATCACA CAGTTTCTTT GGTTATCCCC TGAGCATCTT CTTCATCGTG 
GTCAATGAGT TTTGCGAAAG ATTTTCCTAC TATGGAATGC GAGCAATCCT GATTCTGTAC 
TTCACAAATT TCATCAGCTG GGATGATAAC CTGTCCACCG CCATCTACCA TACGTTTGTG 
GCTCTGTGCT ACCTGACGCC AATTCTCGGA GCTCTTATCG CCGACTCGTG GCTGGGAAAG 
TTCAAGACCA TTGTGTCGCT CTCCATTGTC TACACAATTG GACAAGCAGT CACCTCAGTA 
AGCTCCATTA ATGACCTCAC AGACCACAAC CATGATGGCA CCCCCGACAG CCTTCCTGTG 
CACGTGGTGC TGTCCTTGAT CGGCCTGGCC CTGATAGCTC TCGGGACTGG AGGAATCAAA 
CCCTGTGTGT CTGCGTTTGG TGGAGATCAG TTTGAAGAGG GCCAGGAGAA ACAAAGAAAC 
AGATTTTTTT CCATCTTTTA CTTGGCTATT AATGCTGGAA GTTTGCTTTC CACAATCATC 
ACACCCATGC TCAGAGTTCA ACAATGTGGA ATTCACAGTA AACAAGCTTG TTACCCACTG 
GCCTTTGGGG TTCCTGCTGC TCTCATGGCT GTAGCCCTGA TTGTGTTTGT CCTTGGCAGT 
GGGATGTACA AGAAGTTCAA GCCACAGGGC AACATCATGG GTAAAGTGGC CAAGTGCATC 
GGTTTTGCCA TCAAAAATAG ATTTAGGCAT CGGAGTAAGG CATTTCCCAA GAGGGAGCAC 
TGGCTGGACT GGGCTAAAGA GAAATACGAT GAGCGGCTCA TCTCCCAAAT TAAGATGGTT 
ACGAGGGTGA TGTTCCTGTA TATTCCACTC CCAATGTTCT GGGCCTTGTT TGACCAGCAG 
GGCTCCAGGT GGACACTGCA GGCAACAACT ATGTCCGGGA AAATCGGAGC TCTTGAAATT 
CAGCCCGATC AGATGCAGAC CGTGAACGCC ATCCTGATCG TGATCATGGT CCCGATCTTC 
GATGCTGTGC TGTACCCTCT CATTGCAAAA TGTGGCTTCA ATTTCACCTC CTTGAAGAAG 
ATGGCAGTTG GCATGGTCCT GGCCTCCATG GCCTTTGTGG TGGCTGCCAT CGTGCAGGTG 
GAAATCGATA AAACTCTTCC AGTCTTCCCC AAAGGAAACG AAGTCCAAAT TAAAGTTTTG 
AATATAGGAA ACAATACCAT GAATATATCT CTTCCTGGAG AGATGGTGAC ACTTGGCCCA 
ATGTCTCAAA CAAATGCATT TATGACTTTT GATGTAAACA AACTGACAAG GATAAACATT 
TCTTCTCCTG GATCACCAGT CACTGCTGTA ACTGACGACT TCAAGCAGGG CCAACGCCAC 
ACGCTTCTAG TGTGGGCCCC CAATCACTAC CAGGTGGTAA AGGATGGTCT TAACCAGAAG 
CCAGAAAAAG GGGAAAATGG AATCAGATTT GTAAATACTT TTAACGAGCT CATCACCATC 
ACAATGAGTG GGAAAGTTTA TGCAAACATC AGCAGCTACA ATGCCAGCAC ATACCAGTTT 
TTTCCTTCTG GCATAAAAGG CTTCACAATA AGCTCAACAG AGATTCCGCC ACAATGTCAA 
CCTAATTTCA ATACTTTCTA CCTTGAATTT GGTAGTGCTT ATACCTATAT AGTCCAAAGG 
AAGAATGACA GCTGCCCTGA AGTGAAGGTG TTTGAAGATA TTTCAGCCAA CACAGTTAAC 
ATGGCTCTGC AAATCCCGCA GTATTTTCTT CTCACCTGTG GCGAAGTGGT CTTCTCTGTC 
ACGGGATTGG AATTCTCATA TTCTCAGGCT CCTTCCAACA TGAAGTCGGT GCTTCAGGCA 
GGATGGCTGC TGACCGTGGC TGTTGGCAAC ATCATTGTGC TCATCGTGGC AGGGGCAGGC 
CAGTTCAGCA AACAGTGGGC CGAGTACATT CTATTTGCCG CGTTGCTTCT GGTCGTCTGT 
GTAATTTTTG CCATCATGGC TCGGTTCTAT ACTTACATCA ACCCAGCGGA GATCGAAGCT 
CAATTTGATG AGGATGAAAA GAAAAACAGA CTGGAAAAGA GTAACCCATA TTTCATGTCA 
GGGGCCAATT CACAGAAACA GATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005064.1
CDS	78..2204
Translation	MGMSKSHSFFGYPLSIFFIVVNEFCERFSYYGMRAILILYFTNFISWDDNLSTAIYHTFVALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVTSVSSINDLTDHNHDGTPDSLPVHVVLSLIGLALIALGTGGIKPCVSAFGGDQFEEGQEKQRNRFFSIFYLAINAGSLLSTIITPMLRVQQCGIHSKQACYPLAFGVPAALMAVALIVFVLGSGMYKKFKPQGNIMGKVAKCIGFAIKNRFRHRSKAFPKREHWLDWAKEKYDERLISQIKMVTRVMFLYIPLPMFWALFDQQGSRWTLQATTMSGKIGALEIQPDQMQTVNAILIVIMVPIFDAVLYPLIAKCGFNFTSLKKMAVGMVLASMAFVVAAIVQVEIDKTLPVFPKGNEVQIKVLNIGNNTMNISLPGEMVTLGPMSQTNAFMTFDVNKLTRINISSPGSPVTAVTDDFKQGQRHTLLVWAPNHYQVVKDGLNQKPEKGENGIRFVNTFNELITITMSGKVYANISSYNASTYQFFPSGIKGFTISSTEIPPQCQPNFNTFYLEFGSAYTYIVQRKNDSCPEVKVFEDISANTVNMALQIPQYFLLTCGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLIVAGAGQFSKQWAEYILFAALLLVVCVIFAIMARFYTYINPAEIEAQFDEDEKKNRLEKSNPYFMSGANSQKQM

Target ORF information:

RefSeq Version	NM_005073.3
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 15 member 1 (SLC15A1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005073.3

ORF Insert Sequence:

ATGGGAATGT CCAAATCACA CAGTTTCTTT GGTTATCCCC TGAGCATCTT CTTCATCGTG 
GTCAATGAGT TTTGCGAAAG ATTTTCCTAC TATGGAATGC GAGCAATCCT GATTCTGTAC 
TTCACAAATT TCATCAGCTG GGATGATAAC CTGTCCACCG CCATCTACCA TACGTTTGTG 
GCTCTGTGCT ACCTGACGCC AATTCTCGGA GCTCTTATCG CCGACTCGTG GCTGGGAAAG 
TTCAAGACCA TTGTGTCGCT CTCCATTGTC TACACAATTG GACAAGCAGT CACCTCAGTA 
AGCTCCATTA ATGACCTCAC AGACCACAAC CATGATGGCA CCCCCGACAG CCTTCCTGTG 
CACGTGGTGC TGTCCTTGAT CGGCCTGGCC CTGATAGCTC TCGGGACTGG AGGAATCAAA 
CCCTGTGTGT CTGCGTTTGG TGGAGATCAG TTTGAAGAGG GCCAGGAGAA ACAAAGAAAC 
AGATTTTTTT CCATCTTTTA CTTGGCTATT AATGCTGGAA GTTTGCTTTC CACAATCATC 
ACACCCATGC TCAGAGTTCA ACAATGTGGA ATTCACAGTA AACAAGCTTG TTACCCACTG 
GCCTTTGGGG TTCCTGCTGC TCTCATGGCT GTAGCCCTGA TTGTGTTTGT CCTTGGCAGT 
GGGATGTACA AGAAGTTCAA GCCACAGGGC AACATCATGG GTAAAGTGGC CAAGTGCATC 
GGTTTTGCCA TCAAAAATAG ATTTAGGCAT CGGAGTAAGG CATTTCCCAA GAGGGAGCAC 
TGGCTGGACT GGGCTAAAGA GAAATACGAT GAGCGGCTCA TCTCCCAAAT TAAGATGGTT 
ACGAGGGTGA TGTTCCTGTA TATTCCACTC CCAATGTTCT GGGCCTTGTT TGACCAGCAG 
GGCTCCAGGT GGACACTGCA GGCAACAACT ATGTCCGGGA AAATCGGAGC TCTTGAAATT 
CAGCCCGATC AGATGCAGAC CGTGAACGCC ATCCTGATCG TGATCATGGT CCCGATCTTC 
GATGCTGTGC TGTACCCTCT CATTGCAAAA TGTGGCTTCA ATTTCACCTC CTTGAAGAAG 
ATGGCAGTTG GCATGGTCCT GGCCTCCATG GCCTTTGTGG TGGCTGCCAT CGTGCAGGTG 
GAAATCGATA AAACTCTTCC AGTCTTCCCC AAAGGAAACG AAGTCCAAAT TAAAGTTTTG 
AATATAGGAA ACAATACCAT GAATATATCT CTTCCTGGAG AGATGGTGAC ACTTGGCCCA 
ATGTCTCAAA CAAATGCATT TATGACTTTT GATGTAAACA AACTGACAAG GATAAACATT 
TCTTCTCCTG GATCACCAGT CACTGCTGTA ACTGACGACT TCAAGCAGGG CCAACGCCAC 
ACGCTTCTAG TGTGGGCCCC CAATCACTAC CAGGTGGTAA AGGATGGTCT TAACCAGAAG 
CCAGAAAAAG GGGAAAATGG AATCAGATTT GTAAATACTT TTAACGAGCT CATCACCATC 
ACAATGAGTG GGAAAGTTTA TGCAAACATC AGCAGCTACA ATGCCAGCAC ATACCAGTTT 
TTTCCTTCTG GCATAAAAGG CTTCACAATA AGCTCAACAG AGATTCCGCC ACAATGTCAA 
CCTAATTTCA ATACTTTCTA CCTTGAATTT GGTAGTGCTT ATACCTATAT AGTCCAAAGG 
AAGAATGACA GCTGCCCTGA AGTGAAGGTG TTTGAAGATA TTTCAGCCAA CACAGTTAAC 
ATGGCTCTGC AAATCCCGCA GTATTTTCTT CTCACCTGTG GCGAAGTGGT CTTCTCTGTC 
ACGGGATTGG AATTCTCATA TTCTCAGGCT CCTTCCAACA TGAAGTCGGT GCTTCAGGCA 
GGATGGCTGC TGACCGTGGC TGTTGGCAAC ATCATTGTGC TCATCGTGGC AGGGGCAGGC 
CAGTTCAGCA AACAGTGGGC CGAGTACATT CTATTTGCCG CGTTGCTTCT GGTCGTCTGT 
GTAATTTTTG CCATCATGGC TCGGTTCTAT ACTTACATCA ACCCAGCGGA GATCGAAGCT 
CAATTTGATG AGGATGAAAA GAAAAACAGA CTGGAAAAGA GTAACCCATA TTTCATGTCA 
GGGGCCAATT CACAGAAACA GATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC15A1 ( NM_005073.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005064.1 Homo sapiens solute carrier family 15 member 1 (SLC15A1), mRNA.

Price & Availability↑

CloneID	OHu19511
Clone ID Related Accession (Same CDS sequence)	NM_005073.3 , NM_005073.4
Accession Version	NM_005073.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2127bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	solute carrier family 15 member 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL708816.1, U13173.1, CU445953.1, BC096329.3 and AW449979.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_005073.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U21936.1, BC096329.3 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000376503.10/ ENSP00000365686.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGAATGT CCAAATCACA CAGTTTCTTT GGTTATCCCC TGAGCATCTT CTTCATCGTG 
GTCAATGAGT TTTGCGAAAG ATTTTCCTAC TATGGAATGC GAGCAATCCT GATTCTGTAC 
TTCACAAATT TCATCAGCTG GGATGATAAC CTGTCCACCG CCATCTACCA TACGTTTGTG 
GCTCTGTGCT ACCTGACGCC AATTCTCGGA GCTCTTATCG CCGACTCGTG GCTGGGAAAG 
TTCAAGACCA TTGTGTCGCT CTCCATTGTC TACACAATTG GACAAGCAGT CACCTCAGTA 
AGCTCCATTA ATGACCTCAC AGACCACAAC CATGATGGCA CCCCCGACAG CCTTCCTGTG 
CACGTGGTGC TGTCCTTGAT CGGCCTGGCC CTGATAGCTC TCGGGACTGG AGGAATCAAA 
CCCTGTGTGT CTGCGTTTGG TGGAGATCAG TTTGAAGAGG GCCAGGAGAA ACAAAGAAAC 
AGATTTTTTT CCATCTTTTA CTTGGCTATT AATGCTGGAA GTTTGCTTTC CACAATCATC 
ACACCCATGC TCAGAGTTCA ACAATGTGGA ATTCACAGTA AACAAGCTTG TTACCCACTG 
GCCTTTGGGG TTCCTGCTGC TCTCATGGCT GTAGCCCTGA TTGTGTTTGT CCTTGGCAGT 
GGGATGTACA AGAAGTTCAA GCCACAGGGC AACATCATGG GTAAAGTGGC CAAGTGCATC 
GGTTTTGCCA TCAAAAATAG ATTTAGGCAT CGGAGTAAGG CATTTCCCAA GAGGGAGCAC 
TGGCTGGACT GGGCTAAAGA GAAATACGAT GAGCGGCTCA TCTCCCAAAT TAAGATGGTT 
ACGAGGGTGA TGTTCCTGTA TATTCCACTC CCAATGTTCT GGGCCTTGTT TGACCAGCAG 
GGCTCCAGGT GGACACTGCA GGCAACAACT ATGTCCGGGA AAATCGGAGC TCTTGAAATT 
CAGCCCGATC AGATGCAGAC CGTGAACGCC ATCCTGATCG TGATCATGGT CCCGATCTTC 
GATGCTGTGC TGTACCCTCT CATTGCAAAA TGTGGCTTCA ATTTCACCTC CTTGAAGAAG 
ATGGCAGTTG GCATGGTCCT GGCCTCCATG GCCTTTGTGG TGGCTGCCAT CGTGCAGGTG 
GAAATCGATA AAACTCTTCC AGTCTTCCCC AAAGGAAACG AAGTCCAAAT TAAAGTTTTG 
AATATAGGAA ACAATACCAT GAATATATCT CTTCCTGGAG AGATGGTGAC ACTTGGCCCA 
ATGTCTCAAA CAAATGCATT TATGACTTTT GATGTAAACA AACTGACAAG GATAAACATT 
TCTTCTCCTG GATCACCAGT CACTGCTGTA ACTGACGACT TCAAGCAGGG CCAACGCCAC 
ACGCTTCTAG TGTGGGCCCC CAATCACTAC CAGGTGGTAA AGGATGGTCT TAACCAGAAG 
CCAGAAAAAG GGGAAAATGG AATCAGATTT GTAAATACTT TTAACGAGCT CATCACCATC 
ACAATGAGTG GGAAAGTTTA TGCAAACATC AGCAGCTACA ATGCCAGCAC ATACCAGTTT 
TTTCCTTCTG GCATAAAAGG CTTCACAATA AGCTCAACAG AGATTCCGCC ACAATGTCAA 
CCTAATTTCA ATACTTTCTA CCTTGAATTT GGTAGTGCTT ATACCTATAT AGTCCAAAGG 
AAGAATGACA GCTGCCCTGA AGTGAAGGTG TTTGAAGATA TTTCAGCCAA CACAGTTAAC 
ATGGCTCTGC AAATCCCGCA GTATTTTCTT CTCACCTGTG GCGAAGTGGT CTTCTCTGTC 
ACGGGATTGG AATTCTCATA TTCTCAGGCT CCTTCCAACA TGAAGTCGGT GCTTCAGGCA 
GGATGGCTGC TGACCGTGGC TGTTGGCAAC ATCATTGTGC TCATCGTGGC AGGGGCAGGC 
CAGTTCAGCA AACAGTGGGC CGAGTACATT CTATTTGCCG CGTTGCTTCT GGTCGTCTGT 
GTAATTTTTG CCATCATGGC TCGGTTCTAT ACTTACATCA ACCCAGCGGA GATCGAAGCT 
CAATTTGATG AGGATGAAAA GAAAAACAGA CTGGAAAAGA GTAACCCATA TTTCATGTCA 
GGGGCCAATT CACAGAAACA GATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005064.1
CDS	75..2201
Translation	MGMSKSHSFFGYPLSIFFIVVNEFCERFSYYGMRAILILYFTNFISWDDNLSTAIYHTFVALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVTSVSSINDLTDHNHDGTPDSLPVHVVLSLIGLALIALGTGGIKPCVSAFGGDQFEEGQEKQRNRFFSIFYLAINAGSLLSTIITPMLRVQQCGIHSKQACYPLAFGVPAALMAVALIVFVLGSGMYKKFKPQGNIMGKVAKCIGFAIKNRFRHRSKAFPKREHWLDWAKEKYDERLISQIKMVTRVMFLYIPLPMFWALFDQQGSRWTLQATTMSGKIGALEIQPDQMQTVNAILIVIMVPIFDAVLYPLIAKCGFNFTSLKKMAVGMVLASMAFVVAAIVQVEIDKTLPVFPKGNEVQIKVLNIGNNTMNISLPGEMVTLGPMSQTNAFMTFDVNKLTRINISSPGSPVTAVTDDFKQGQRHTLLVWAPNHYQVVKDGLNQKPEKGENGIRFVNTFNELITITMSGKVYANISSYNASTYQFFPSGIKGFTISSTEIPPQCQPNFNTFYLEFGSAYTYIVQRKNDSCPEVKVFEDISANTVNMALQIPQYFLLTCGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLIVAGAGQFSKQWAEYILFAALLLVVCVIFAIMARFYTYINPAEIEAQFDEDEKKNRLEKSNPYFMSGANSQKQM

Target ORF information:

RefSeq Version	NM_005073.4
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 15 member 1 (SLC15A1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005073.4

ORF Insert Sequence:

ATGGGAATGT CCAAATCACA CAGTTTCTTT GGTTATCCCC TGAGCATCTT CTTCATCGTG 
GTCAATGAGT TTTGCGAAAG ATTTTCCTAC TATGGAATGC GAGCAATCCT GATTCTGTAC 
TTCACAAATT TCATCAGCTG GGATGATAAC CTGTCCACCG CCATCTACCA TACGTTTGTG 
GCTCTGTGCT ACCTGACGCC AATTCTCGGA GCTCTTATCG CCGACTCGTG GCTGGGAAAG 
TTCAAGACCA TTGTGTCGCT CTCCATTGTC TACACAATTG GACAAGCAGT CACCTCAGTA 
AGCTCCATTA ATGACCTCAC AGACCACAAC CATGATGGCA CCCCCGACAG CCTTCCTGTG 
CACGTGGTGC TGTCCTTGAT CGGCCTGGCC CTGATAGCTC TCGGGACTGG AGGAATCAAA 
CCCTGTGTGT CTGCGTTTGG TGGAGATCAG TTTGAAGAGG GCCAGGAGAA ACAAAGAAAC 
AGATTTTTTT CCATCTTTTA CTTGGCTATT AATGCTGGAA GTTTGCTTTC CACAATCATC 
ACACCCATGC TCAGAGTTCA ACAATGTGGA ATTCACAGTA AACAAGCTTG TTACCCACTG 
GCCTTTGGGG TTCCTGCTGC TCTCATGGCT GTAGCCCTGA TTGTGTTTGT CCTTGGCAGT 
GGGATGTACA AGAAGTTCAA GCCACAGGGC AACATCATGG GTAAAGTGGC CAAGTGCATC 
GGTTTTGCCA TCAAAAATAG ATTTAGGCAT CGGAGTAAGG CATTTCCCAA GAGGGAGCAC 
TGGCTGGACT GGGCTAAAGA GAAATACGAT GAGCGGCTCA TCTCCCAAAT TAAGATGGTT 
ACGAGGGTGA TGTTCCTGTA TATTCCACTC CCAATGTTCT GGGCCTTGTT TGACCAGCAG 
GGCTCCAGGT GGACACTGCA GGCAACAACT ATGTCCGGGA AAATCGGAGC TCTTGAAATT 
CAGCCCGATC AGATGCAGAC CGTGAACGCC ATCCTGATCG TGATCATGGT CCCGATCTTC 
GATGCTGTGC TGTACCCTCT CATTGCAAAA TGTGGCTTCA ATTTCACCTC CTTGAAGAAG 
ATGGCAGTTG GCATGGTCCT GGCCTCCATG GCCTTTGTGG TGGCTGCCAT CGTGCAGGTG 
GAAATCGATA AAACTCTTCC AGTCTTCCCC AAAGGAAACG AAGTCCAAAT TAAAGTTTTG 
AATATAGGAA ACAATACCAT GAATATATCT CTTCCTGGAG AGATGGTGAC ACTTGGCCCA 
ATGTCTCAAA CAAATGCATT TATGACTTTT GATGTAAACA AACTGACAAG GATAAACATT 
TCTTCTCCTG GATCACCAGT CACTGCTGTA ACTGACGACT TCAAGCAGGG CCAACGCCAC 
ACGCTTCTAG TGTGGGCCCC CAATCACTAC CAGGTGGTAA AGGATGGTCT TAACCAGAAG 
CCAGAAAAAG GGGAAAATGG AATCAGATTT GTAAATACTT TTAACGAGCT CATCACCATC 
ACAATGAGTG GGAAAGTTTA TGCAAACATC AGCAGCTACA ATGCCAGCAC ATACCAGTTT 
TTTCCTTCTG GCATAAAAGG CTTCACAATA AGCTCAACAG AGATTCCGCC ACAATGTCAA 
CCTAATTTCA ATACTTTCTA CCTTGAATTT GGTAGTGCTT ATACCTATAT AGTCCAAAGG 
AAGAATGACA GCTGCCCTGA AGTGAAGGTG TTTGAAGATA TTTCAGCCAA CACAGTTAAC 
ATGGCTCTGC AAATCCCGCA GTATTTTCTT CTCACCTGTG GCGAAGTGGT CTTCTCTGTC 
ACGGGATTGG AATTCTCATA TTCTCAGGCT CCTTCCAACA TGAAGTCGGT GCTTCAGGCA 
GGATGGCTGC TGACCGTGGC TGTTGGCAAC ATCATTGTGC TCATCGTGGC AGGGGCAGGC 
CAGTTCAGCA AACAGTGGGC CGAGTACATT CTATTTGCCG CGTTGCTTCT GGTCGTCTGT 
GTAATTTTTG CCATCATGGC TCGGTTCTAT ACTTACATCA ACCCAGCGGA GATCGAAGCT 
CAATTTGATG AGGATGAAAA GAAAAACAGA CTGGAAAAGA GTAACCCATA TTTCATGTCA 
GGGGCCAATT CACAGAAACA GATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Regulation profile of the intestinal peptide transporter 1 (PepT1).
Drug design, development and therapy113511-3517(2017)
Wang CY,Liu S,Xie XN,Tan ZR

Human Intestinal PEPT1 Transporter Expression and Localization in Preterm and Term Infants.
Drug metabolism and disposition: the biological fate of chemicals44(7)1014-9(2016 Jul)
Mooij MG,de Koning BE,Lindenbergh-Kortleve DJ,Simons-Oosterhuis Y,van Groen BD,Tibboel D,Samsom JN,de Wildt SN

Species differences in the pharmacokinetics of cefadroxil as determined in wildtype and humanized PepT1 mice.
Biochemical pharmacology10781-90(2016 May)
Hu Y,Smith DE

A new target ligand Ser-Glu for PEPT1-overexpressing cancer imaging.
International journal of nanomedicine11203-12(2016)
Dai T,Li N,Zhang L,Zhang Y,Liu Q

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SLC15A1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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