Slc15a1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc15a1
Entrez Gene ID	117261
Full Name	solute carrier family 15 member 1
Synonyms	Pept1
General protein information	Preferred Names solute carrier family 15 member 1 Names solute carrier family 15 member 1 intestinal H(+)/peptide cotransporter oligopeptide transporter, small intestine isoform peptide transporter 1 pineal gland-specific PEPT1 proton-coupled dipeptide cotransporter solute carrier family 15 (oligopeptide transporter), member 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 15 Map Location: 15q24
Summary	acts as a proton dependent peptide transporter; may transport oral beta-lactam antibiotics across intestinal brush borders [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006252470.3	XP_006252532.1	solute carrier family 15 member 1 isoform X1
NM_057121.1	NP_476462.1	solute carrier family 15 member 1 isoform PepT1
NM_001079838.1	NP_001073307.1	solute carrier family 15 member 1 isoform pgPepT1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SLC15A1	XP_522705.3
Canis lupus familiaris (dog)	SLC15A1	NP_001003036.1
Schizosaccharomyces pombe (fission yeast)	SPBC13A2.04c	NP_596417.1
	SLC15A1	NP_001028071.1
Danio rerio (zebrafish)	slc15a1b	NP_932330.1
Saccharomyces cerevisiae (baker's yeast)	PTR2	NP_013019.1
Oryza sativa (rice)	Os03g0719900	NP_001051098.1
Rattus norvegicus (Norway rat)	Slc15a1	NP_476462.1
Gallus gallus (chicken)	SLC15A1	NP_989696.1
Danio rerio (zebrafish)	slc15a1a	XP_001919914.3
Caenorhabditis elegans (roundworm)	pept-1	NP_509087.1
Xenopus tropicalis (tropical clawed frog)	slc15a1	XP_002935692.2
Bos taurus (cattle)	SLC15A1	NP_001092848.1
Drosophila melanogaster (fruit fly)	CG2930	NP_788857.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010383	XP_311562.3
Kluyveromyces lactis	KLLA0E12915g	XP_454532.1
Homo sapiens (human)	SLC15A1	NP_005064.1
Mus musculus (house mouse)	Slc15a1	NP_444309.2
Caenorhabditis elegans (roundworm)	pept-2	NP_502002.1
Arabidopsis thaliana (thale cress)	PTR2	NP_178313.1

Gene Ontology
Bibliography

Related articles in PubMed

Evaluation of PepT1 transport of food-derived antihypertensive peptides, Ile-Pro-Pro and Leu-Lys-Pro using in vitro, ex vivo and in vivo transport models.
Gleeson JP, Brayden DJ, Ryan SM
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V115276-284(2017 Jun)

Ghrelin upregulates PepT1 activity in the small intestine epithelium of rats with sepsis.
Liu J, Shi B, Shi K, Ma G, Zhang H, Lou X, Liu H, Wan S, Liang D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie86669-676(2017 Feb)

Nod2-Rip2 Signaling Contributes to Intestinal Injury Induced by Muramyl Dipeptide Via Oligopeptide Transporter in Rats.
Ma G, Shi B, Liu J, Zhang H, YinTao Z, Lou X, Liang D, Hou Y, Wan S, Yang W
Digestive diseases and sciences60(11)3264-70(2015 Nov)

Slc15a1 is involved in the transport of synthetic F5-peptide into the seminiferous epithelium in adult rat testes.
Su L, Zhang Y, Cheng YC, Lee WM, Ye K, Hu D
Scientific reports516271(2015 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The expressions of PepT1 mRNA and protein were higher in ghrelin-treated group rats.
Title: Ghrelin upregulates PepT1 activity in the small intestine epithelium of rats with sepsis.

Nod2-Rip2-NFkappaB signaling involved in the small intestinal inflammatory injury caused by muramyl dipeptide which is transported through PepT1.
Title: Nod2-Rip2 Signaling Contributes to Intestinal Injury Induced by Muramyl Dipeptide Via Oligopeptide Transporter in Rats.

Slc15a1 is involved in the transport of synthetic F5-peptide into seminiferous epithelium.
Title: Slc15a1 is involved in the transport of synthetic F5-peptide into the seminiferous epithelium in adult rat testes.

Data suggest that PepT1 transports the vasoactive dipeptide Trp-His (but not His-Trp which undergoes rapid proteolysis) across the rat intestinal membrane; this mechanism may account for anti-atherosclerotic action of Trp-His as a dietary supplement.
Title: Visualized absorption of anti-atherosclerotic dipeptide, Trp-His, in Sprague-Dawley rats by LC-MS and MALDI-MS imaging analyses.

GIP via GIPR activates two signaling pathways, the cAMP pathway through Epac and the PI3K pathway through Akt, to increase the trafficking of PepT1 proteins to the apical membrane.
Title: Glucose-dependent insulinotropic polypeptide-mediated signaling pathways enhance apical PepT1 expression in intestinal epithelial cells.

The following Slc15a1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc15a1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa11379	NM_057121.1 Latest version!	Rattus norvegicus solute carrier family 15 member 1 (Slc15a1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
ORa10564	NM_001079838.1 Latest version!	Rattus norvegicus solute carrier family 15 member 1 (Slc15a1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa36939	XM_006252470.3 Latest version!	Rattus norvegicus solute carrier family 15 member 1 (Slc15a1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc15a1 ( NM_057121.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_476462.1 Rattus norvegicus solute carrier family 15 member 1 (Slc15a1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa11379
Clone ID Related Accession (Same CDS sequence)	NM_057121.1
Accession Version	NM_057121.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2133bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-03
Organism	Rattus norvegicus(Norway rat)
Product	solute carrier family 15 member 1 isoform PepT1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from D50664.1. On Dec 17, 2003 this sequence version replaced XM_346478.1. Transcript Variant: This variant (1) encodes the longer isoform (PepT1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D50664.1, D50306.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGGGATGT CCAAGTCTCG GGGTTGCTTT GGCTACCCAT TGAGCATCTT CTTCATCGTG 
GTCAATGAAT TCTGTGAAAG ATTCTCCTAC TATGGGATGC GAGCTCTCCT GGTTCTGTAC 
TTCAGGAACT TCCTTGGCTG GGATGATGAC CTCTCCACGG CCATCTACCA TACGTTTGTT 
GCCCTCTGCT ACCTGACTCC AATTCTTGGA GCTCTGATCG CAGACTCGTG GCTGGGGAAG 
TTCAAGACAA TTGTCTCACT ATCCATCGTC TACACGATCG GACAGGCCGT CATCTCAGTG 
AGCTCAATTA ATGACCTTAC AGACCATGAC CACGACGGCA GTCCTAACAA CCTTCCTTTG 
CACGTAGCAC TGTCCATGAT CGGCCTGGCC CTGATAGCCC TTGGTACAGG AGGAATCAAG 
CCCTGTGTGT CTGCATTTGG TGGCGATCAG TTTGAAGAGG GTCAGGAAAA ACAGCGAAAC 
CGGTTCTTTT CCATCTTTTA TTTGGCTATC AACGCAGGAA GCCTGCTCTC CACGATCATC 
ACTCCCATAC TCAGAGTTCA GCAGTGCGGA ATCCACAGCC AACAAGCTTG TTACCCACTG 
GCCTTTGGGG TTCCGGCAGC TCTCATGGCT GTTGCCCTAA TTGTGTTTGT CCTCGGCAGT 
GGAATGTACA AGAAGTTTCA GCCCCAGGGC AACATCATGG GCAAAGTGGC CAAGTGCATT 
CGGTTTGCCA TCAAAAACAG GTTTCGGCAC CGAAGTAAGG CATTTCCCAA GAGGAACCAC 
TGGCTGGACT GGGCTAAAGA GAAATACGAT GAGAGGCTCA TCTCGCAGAT TAAGATAATG 
ACGAAGGTGA TGTTCCTGTA CATTCCCCTC CCCATGTTTT GGGCCTTGTT TGACCAGCAG 
GGTTCCAGGT GGACACTGCA AGCAACGACC ATGACTGGGA AAATTGGAAC AATTGAGATT 
CAGCCGGACC AGATGCAGAC GGTGAACGCC ATCTTGATTG TCATCATGGT CCCCATTGTG 
GACGCCGTGG TGTATCCGCT CATTGCAAAA TGTGGTTTCA ACTTCACCTC CCTGAAGAAG 
ATGACCGTTG GGATGTTCCT GGCATCCATG GCCTTTGTGG TGGCTGCAAT TGTGCAGGTG 
GAAATCGATA AAACTCTTCC AGTCTTCCCC AGCGGAAATC AAGTTCAAAT TAAGGTCTTG 
AACATTGGAA ACAATGACAT GGCCGTGTAT TTTCCTGGAA AGAATGTGAC AGTTGCCCAA 
ATGTCTCAGA CAGACACATT CATGACTTTC GATGTAGACC AGCTGACAAG CATAAACGTG 
TCTTCTCCCG GATCTCCAGG CGTCACCACG GTAGCTCATG AGTTTGAGCC GGGTCACCGG 
CACACCCTTC TAGTGTGGGG CCCCAATCTA TACCGTGTGG TAAAAGACGG TCTTAACCAA 
AAGCCAGAGA AAGGGGAGAA CGGAATCAGA TTCGTCAGCA CCCTTAACGA GATGATCACC 
ATCAAAATGA GTGGAAAAGT GTACGAAAAT GTCACCAGTC ACAGCGCCAG CAACTATCAG 
TTTTTCCCTT CTGGCCAAAA AGACTACACA ATAAACACCA CAGAGATTGC ACCAAACTGT 
TCATCTGATT TTAAATCTTC CAACCTTGAC TTCGGCAGCG CGTACACCTA CGTGATCAGA 
AGTAGGGCGA GTGATGGCTG CCTGGAAGTG AAGGAATTCG AAGACATCCC ACCCAACACG 
GTGAACATGG CCCTGCAGAT CCCACAGTAC TTCCTCCTCA CCTGCGGCGA GGTGGTCTTC 
TCTGTCACAG GACTGGAGTT CTCCTATTCC CAGGCCCCGT CTAACATGAA GTCCGTGCTT 
CAGGCAGGAT GGCTTCTAAC CGTGGCCATC GGTAATATCA TTGTCCTCAT TGTGGCTGAG 
GCAGGCCACT TCGACAAACA GTGGGCTGAG TATGTTCTGT TCGCCTCCTT GCTCCTGGTC 
GTCTGCATCA TATTTGCCAT TATGGCCCGA TTCTACACCT ACATCAACCC AGCAGAGATC 
GAGGCACAGT TCGATGAGGA TGAGAAGAAA AAGGGCGTAG GGAAGGAAAA CCCGTATTCC 
TCGTTGGAAC CTGTCTCACA GACAAACATG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_476462.1
CDS	52..2184
Translation	MGMSKSRGCFGYPLSIFFIVVNEFCERFSYYGMRALLVLYFRNFLGWDDDLSTAIYHTFVALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVISVSSINDLTDHDHDGSPNNLPLHVALSMIGLALIALGTGGIKPCVSAFGGDQFEEGQEKQRNRFFSIFYLAINAGSLLSTIITPILRVQQCGIHSQQACYPLAFGVPAALMAVALIVFVLGSGMYKKFQPQGNIMGKVAKCIRFAIKNRFRHRSKAFPKRNHWLDWAKEKYDERLISQIKIMTKVMFLYIPLPMFWALFDQQGSRWTLQATTMTGKIGTIEIQPDQMQTVNAILIVIMVPIVDAVVYPLIAKCGFNFTSLKKMTVGMFLASMAFVVAAIVQVEIDKTLPVFPSGNQVQIKVLNIGNNDMAVYFPGKNVTVAQMSQTDTFMTFDVDQLTSINVSSPGSPGVTTVAHEFEPGHRHTLLVWGPNLYRVVKDGLNQKPEKGENGIRFVSTLNEMITIKMSGKVYENVTSHSASNYQFFPSGQKDYTINTTEIAPNCSSDFKSSNLDFGSAYTYVIRSRASDGCLEVKEFEDIPPNTVNMALQIPQYFLLTCGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLLTVAIGNIIVLIVAEAGHFDKQWAEYVLFASLLLVVCIIFAIMARFYTYINPAEIEAQFDEDEKKKGVGKENPYSSLEPVSQTNM

Target ORF information:

RefSeq Version	NM_057121.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 15 member 1 (Slc15a1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_057121.1

ORF Insert Sequence:

ATGGGGATGT CCAAGTCTCG GGGTTGCTTT GGCTACCCAT TGAGCATCTT CTTCATCGTG 
GTCAATGAAT TCTGTGAAAG ATTCTCCTAC TATGGGATGC GAGCTCTCCT GGTTCTGTAC 
TTCAGGAACT TCCTTGGCTG GGATGATGAC CTCTCCACGG CCATCTACCA TACGTTTGTT 
GCCCTCTGCT ACCTGACTCC AATTCTTGGA GCTCTGATCG CAGACTCGTG GCTGGGGAAG 
TTCAAGACAA TTGTCTCACT ATCCATCGTC TACACGATCG GACAGGCCGT CATCTCAGTG 
AGCTCAATTA ATGACCTTAC AGACCATGAC CACGACGGCA GTCCTAACAA CCTTCCTTTG 
CACGTAGCAC TGTCCATGAT CGGCCTGGCC CTGATAGCCC TTGGTACAGG AGGAATCAAG 
CCCTGTGTGT CTGCATTTGG TGGCGATCAG TTTGAAGAGG GTCAGGAAAA ACAGCGAAAC 
CGGTTCTTTT CCATCTTTTA TTTGGCTATC AACGCAGGAA GCCTGCTCTC CACGATCATC 
ACTCCCATAC TCAGAGTTCA GCAGTGCGGA ATCCACAGCC AACAAGCTTG TTACCCACTG 
GCCTTTGGGG TTCCGGCAGC TCTCATGGCT GTTGCCCTAA TTGTGTTTGT CCTCGGCAGT 
GGAATGTACA AGAAGTTTCA GCCCCAGGGC AACATCATGG GCAAAGTGGC CAAGTGCATT 
CGGTTTGCCA TCAAAAACAG GTTTCGGCAC CGAAGTAAGG CATTTCCCAA GAGGAACCAC 
TGGCTGGACT GGGCTAAAGA GAAATACGAT GAGAGGCTCA TCTCGCAGAT TAAGATAATG 
ACGAAGGTGA TGTTCCTGTA CATTCCCCTC CCCATGTTTT GGGCCTTGTT TGACCAGCAG 
GGTTCCAGGT GGACACTGCA AGCAACGACC ATGACTGGGA AAATTGGAAC AATTGAGATT 
CAGCCGGACC AGATGCAGAC GGTGAACGCC ATCTTGATTG TCATCATGGT CCCCATTGTG 
GACGCCGTGG TGTATCCGCT CATTGCAAAA TGTGGTTTCA ACTTCACCTC CCTGAAGAAG 
ATGACCGTTG GGATGTTCCT GGCATCCATG GCCTTTGTGG TGGCTGCAAT TGTGCAGGTG 
GAAATCGATA AAACTCTTCC AGTCTTCCCC AGCGGAAATC AAGTTCAAAT TAAGGTCTTG 
AACATTGGAA ACAATGACAT GGCCGTGTAT TTTCCTGGAA AGAATGTGAC AGTTGCCCAA 
ATGTCTCAGA CAGACACATT CATGACTTTC GATGTAGACC AGCTGACAAG CATAAACGTG 
TCTTCTCCCG GATCTCCAGG CGTCACCACG GTAGCTCATG AGTTTGAGCC GGGTCACCGG 
CACACCCTTC TAGTGTGGGG CCCCAATCTA TACCGTGTGG TAAAAGACGG TCTTAACCAA 
AAGCCAGAGA AAGGGGAGAA CGGAATCAGA TTCGTCAGCA CCCTTAACGA GATGATCACC 
ATCAAAATGA GTGGAAAAGT GTACGAAAAT GTCACCAGTC ACAGCGCCAG CAACTATCAG 
TTTTTCCCTT CTGGCCAAAA AGACTACACA ATAAACACCA CAGAGATTGC ACCAAACTGT 
TCATCTGATT TTAAATCTTC CAACCTTGAC TTCGGCAGCG CGTACACCTA CGTGATCAGA 
AGTAGGGCGA GTGATGGCTG CCTGGAAGTG AAGGAATTCG AAGACATCCC ACCCAACACG 
GTGAACATGG CCCTGCAGAT CCCACAGTAC TTCCTCCTCA CCTGCGGCGA GGTGGTCTTC 
TCTGTCACAG GACTGGAGTT CTCCTATTCC CAGGCCCCGT CTAACATGAA GTCCGTGCTT 
CAGGCAGGAT GGCTTCTAAC CGTGGCCATC GGTAATATCA TTGTCCTCAT TGTGGCTGAG 
GCAGGCCACT TCGACAAACA GTGGGCTGAG TATGTTCTGT TCGCCTCCTT GCTCCTGGTC 
GTCTGCATCA TATTTGCCAT TATGGCCCGA TTCTACACCT ACATCAACCC AGCAGAGATC 
GAGGCACAGT TCGATGAGGA TGAGAAGAAA AAGGGCGTAG GGAAGGAAAA CCCGTATTCC 
TCGTTGGAAC CTGTCTCACA GACAAACATG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc15a1 ( NM_001079838.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001073307.1 Rattus norvegicus solute carrier family 15 member 1 (Slc15a1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	ORa10564
Clone ID Related Accession (Same CDS sequence)	NM_001079838.1
Accession Version	NM_001079838.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 453bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-03
Organism	Rattus norvegicus(Norway rat)
Product	solute carrier family 15 member 1 isoform pgPepT1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY860424.1. Transcript Variant: This variant (2) lacks alternate exons in the 5' UTR and 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (pgPepT1) has a distinct N-terminus and is shorter than isoform PepT1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY860424.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMEA2689597 [ECO:0000348] ##Evidence-Data-END##

ATGGTCCAGA GTGATGGCTG CCTGGAAGTG AAGGAATTCG AAGACATCCC ACCCAACACG 
GTGAACATGG CCCTGCAGAT CCCACAGTAC TTCCTCCTCA CCTGCGGCGA GGTGGTCTTC 
TCTGTCACAG GACTGGAGTT CTCCTATTCC CAGGCCCCGT CTAACATGAA GTCCGTGCTT 
CAGGCAGGAT GGCTTCTAAC CGTGGCCATC GGTAATATCA TTGTCCTCAT TGTGGCTGAG 
GCAGGCCACT TCGACAAACA GTGGGCTGAG TATGTTCTGT TCGCCTCCTT GCTCCTGGTC 
GTCTGCATCA TATTTGCCAT TATGGCCCGA TTCTACACCT ACATCAACCC AGCAGAGATC 
GAGGCACAGT TCGATGAGGA TGAGAAGAAA AAGGGCGTAG GGAAGGAAAA CCCGTATTCC 
TCGTTGGAAC CTGTCTCACA GACAAACATG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001073307.1
CDS	97..549
Translation	MVQSDGCLEVKEFEDIPPNTVNMALQIPQYFLLTCGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLLTVAIGNIIVLIVAEAGHFDKQWAEYVLFASLLLVVCIIFAIMARFYTYINPAEIEAQFDEDEKKKGVGKENPYSSLEPVSQTNM

Target ORF information:

RefSeq Version	NM_001079838.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 15 member 1 (Slc15a1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001079838.1

ORF Insert Sequence:

ATGGTCCAGA GTGATGGCTG CCTGGAAGTG AAGGAATTCG AAGACATCCC ACCCAACACG 
GTGAACATGG CCCTGCAGAT CCCACAGTAC TTCCTCCTCA CCTGCGGCGA GGTGGTCTTC 
TCTGTCACAG GACTGGAGTT CTCCTATTCC CAGGCCCCGT CTAACATGAA GTCCGTGCTT 
CAGGCAGGAT GGCTTCTAAC CGTGGCCATC GGTAATATCA TTGTCCTCAT TGTGGCTGAG 
GCAGGCCACT TCGACAAACA GTGGGCTGAG TATGTTCTGT TCGCCTCCTT GCTCCTGGTC 
GTCTGCATCA TATTTGCCAT TATGGCCCGA TTCTACACCT ACATCAACCC AGCAGAGATC 
GAGGCACAGT TCGATGAGGA TGAGAAGAAA AAGGGCGTAG GGAAGGAAAA CCCGTATTCC 
TCGTTGGAAC CTGTCTCACA GACAAACATG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc15a1 ( XM_006252470.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006252532.1 Rattus norvegicus solute carrier family 15 member 1 (Slc15a1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa36939
Clone ID Related Accession (Same CDS sequence)	XM_006252470.3
Accession Version	XM_006252470.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2217bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	solute carrier family 15 member 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006252470.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGATGT CCAAGTCTCG GGGTTGCTTT GGCTACCCAT TGAGCATCTT CTTCATCGTG 
GTCAATGAAT TCTGTGAAAG ATTCTCCTAC TATGGGATGC GAGCTCTCCT GGTTCTGTAC 
TTCAGGAACT TCCTTGGCTG GGATGATGAC CTCTCCACGG CCATCTACCA TACGTTTGTT 
GCCCTCTGCT ACCTGACGCC AATTCTTGGA GCTCTGATCG CAGACTCGTG GCTGGGGAAG 
TTCAAGACAA TTGTCTCACT ATCCATCGTC TACACGATCG GACAGGCCGT CATCTCAGTG 
AGCTCAATTA ATGACCTTAC AGACCATGAC CACGACGGCA GTCCTAACAA CCTTCCTTTG 
CACGTAGCAC TGTCCATGAT CGGCCTGGCC CTGATAGCCC TTGGTACAGG AGGAATCAAG 
CCCTGTGTGT CTGCATTTGG TGGCGATCAG TTTGAAGAGG GTCAGGAAAA ACAGCGAAAC 
CGGTTCTTTT CCATCTTTTA TTTGGCTATC AACGCAGGAA GCCTGCTCTC CACGATCATC 
ACTCCCATAC TCAGAGTTCA GCAGTGCGGA ATCCACAGCC AACAAGCTTG TTACCCACTG 
GCCTTTGGGG TTCCGGCAGC TCTCATGGCT GTTGCCCTAA TTGTGTTTGT CCTCGGCAGT 
GGAATGTACA AGAAGTTTCA GCCCCAGGGC AACATCATGG GCAAAGTGGC CAAGTGCATT 
GGCTTTGCCA TCAAAAACAG GTTTCGGCAC CGAAGTAAGG CATTTCCCAA GAGGGAACAC 
TGGCTGGACT GGGCTAAAGA GAAATACGAT GAGAGGCTCA TCTCGCAGAT TAAGATGGTG 
ACGAAGGTGA TGTTCCTGTA CATTCCCCTC CCCATGTTTT GGGCCTTGTT TGACCAGCAG 
GGTTCCAGGT GGACACTGCA AGCAACGACC ATGACTGGGA AAATTGGAAC AATTGAGATT 
CAGCCGGACC AGATGCAGGT AGGAGAAAGG GCTCGGCTCA CTTTCCGAGG CCCACGTGTT 
CCTTGTGATT GCACTAACGG CCCCTCTCCA CTTCCTCTGC AGACGGTGAA CGCCATCTTG 
ATTGTCATCA TGGTCCCCAT TGTGGACGCC GTGGTGTATC CGCTCATTGC AAAATGTGGT 
TTCAACTTCA CCTCCCTGAA GAAGATGACC GTTGGGATGT TCCTGGCATC CATGGCCTTT 
GTGGTGGCTG CAATTGTGCA GGTGGAAATC GATAAAACTC TTCCAGTCTT CCCCAGCGGA 
AATCAAGTTC AAATTAAGGT CTTGAACATT GGAAACAATG ACATGGCCGT GTATTTTCCT 
GGAAAGAATG TGACAGTTGC CCAAATGTCT CAGACAGACA CATTCATGAC TTTCGATGTA 
GACCAGCTGA CAAGCATAAA CGTGTCTTCT CCCGGATCTC CAGGCGTCAC CACGGTAGCT 
CATGAGTTTG AGCCGGGTCA CCGGCACACC CTTCTAGTGT GGGGCCCCAA TCTATACCGT 
GTGGTAAAAG ACGGTCTTAA CCAAAAGCCA GAGAAAGGGG AGAACGGAAT CAGATTCGTC 
AGCACCCTTA ACGAGATGAT CACCATCAAA ATGAGTGGAA AAGTGTACGA AAATGTCACC 
AGTCACAGCG CCAGCAACTA CCAGTTTTTC CCTTCTGGCC AAAAAGACTA CACAATAAAC 
ACCACAGAGA TTGCACCAAA CTGTTCATCT GATTTTAAAT CTTCCAACCT TGACTTCGGC 
AGCGCGTACA CCTACGTGAT CAGAAGTAGG GCGAGTGATG GCTGCCTGGA AGTGAAGGAA 
TTCGAAGACA TCCCACCCAA CACGGTGAAC ATGGCCCTGC AGATCCCACA GTACTTCCTC 
CTCACCTGCG GCGAGGTGGT CTTCTCTGTC ACAGGACTGG AGTTCTCCTA TTCCCAGGCC 
CCGTCTAACA TGAAGTCCGT GCTTCAGGCA GGATGGCTTC TAACCGTGGC CATCGGTAAT 
ATCATTGTCC TCATTGTGGC TGAGGCAGGC CACTTCGACA AACAGTGGGC TGAGTATGTT 
CTGTTCGCCT CCTTGCTCCT GGTCGTCTGC ATCATATTTG CCATTATGGC CCGATTCTAC 
ACCTACATCA ACCCAGCAGA GATCGAGGCA CAGTTCGATG AGGATGAGAA GAAAAAGGGC 
GTAGGGAAGG AAAACCCGTA TTCCTCGTTG GAACCTGTCT CACAGACAAA CATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006252532.1
CDS	291..2507
Translation	MGMSKSRGCFGYPLSIFFIVVNEFCERFSYYGMRALLVLYFRNFLGWDDDLSTAIYHTFVALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVISVSSINDLTDHDHDGSPNNLPLHVALSMIGLALIALGTGGIKPCVSAFGGDQFEEGQEKQRNRFFSIFYLAINAGSLLSTIITPILRVQQCGIHSQQACYPLAFGVPAALMAVALIVFVLGSGMYKKFQPQGNIMGKVAKCIGFAIKNRFRHRSKAFPKREHWLDWAKEKYDERLISQIKMVTKVMFLYIPLPMFWALFDQQGSRWTLQATTMTGKIGTIEIQPDQMQVGERARLTFRGPRVPCDCTNGPSPLPLQTVNAILIVIMVPIVDAVVYPLIAKCGFNFTSLKKMTVGMFLASMAFVVAAIVQVEIDKTLPVFPSGNQVQIKVLNIGNNDMAVYFPGKNVTVAQMSQTDTFMTFDVDQLTSINVSSPGSPGVTTVAHEFEPGHRHTLLVWGPNLYRVVKDGLNQKPEKGENGIRFVSTLNEMITIKMSGKVYENVTSHSASNYQFFPSGQKDYTINTTEIAPNCSSDFKSSNLDFGSAYTYVIRSRASDGCLEVKEFEDIPPNTVNMALQIPQYFLLTCGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLLTVAIGNIIVLIVAEAGHFDKQWAEYVLFASLLLVVCIIFAIMARFYTYINPAEIEAQFDEDEKKKGVGKENPYSSLEPVSQTNM

Target ORF information:

RefSeq Version	XM_006252470.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 15 member 1 (Slc15a1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006252470.3

ORF Insert Sequence:

ATGGGGATGT CCAAGTCTCG GGGTTGCTTT GGCTACCCAT TGAGCATCTT CTTCATCGTG 
GTCAATGAAT TCTGTGAAAG ATTCTCCTAC TATGGGATGC GAGCTCTCCT GGTTCTGTAC 
TTCAGGAACT TCCTTGGCTG GGATGATGAC CTCTCCACGG CCATCTACCA TACGTTTGTT 
GCCCTCTGCT ACCTGACGCC AATTCTTGGA GCTCTGATCG CAGACTCGTG GCTGGGGAAG 
TTCAAGACAA TTGTCTCACT ATCCATCGTC TACACGATCG GACAGGCCGT CATCTCAGTG 
AGCTCAATTA ATGACCTTAC AGACCATGAC CACGACGGCA GTCCTAACAA CCTTCCTTTG 
CACGTAGCAC TGTCCATGAT CGGCCTGGCC CTGATAGCCC TTGGTACAGG AGGAATCAAG 
CCCTGTGTGT CTGCATTTGG TGGCGATCAG TTTGAAGAGG GTCAGGAAAA ACAGCGAAAC 
CGGTTCTTTT CCATCTTTTA TTTGGCTATC AACGCAGGAA GCCTGCTCTC CACGATCATC 
ACTCCCATAC TCAGAGTTCA GCAGTGCGGA ATCCACAGCC AACAAGCTTG TTACCCACTG 
GCCTTTGGGG TTCCGGCAGC TCTCATGGCT GTTGCCCTAA TTGTGTTTGT CCTCGGCAGT 
GGAATGTACA AGAAGTTTCA GCCCCAGGGC AACATCATGG GCAAAGTGGC CAAGTGCATT 
GGCTTTGCCA TCAAAAACAG GTTTCGGCAC CGAAGTAAGG CATTTCCCAA GAGGGAACAC 
TGGCTGGACT GGGCTAAAGA GAAATACGAT GAGAGGCTCA TCTCGCAGAT TAAGATGGTG 
ACGAAGGTGA TGTTCCTGTA CATTCCCCTC CCCATGTTTT GGGCCTTGTT TGACCAGCAG 
GGTTCCAGGT GGACACTGCA AGCAACGACC ATGACTGGGA AAATTGGAAC AATTGAGATT 
CAGCCGGACC AGATGCAGGT AGGAGAAAGG GCTCGGCTCA CTTTCCGAGG CCCACGTGTT 
CCTTGTGATT GCACTAACGG CCCCTCTCCA CTTCCTCTGC AGACGGTGAA CGCCATCTTG 
ATTGTCATCA TGGTCCCCAT TGTGGACGCC GTGGTGTATC CGCTCATTGC AAAATGTGGT 
TTCAACTTCA CCTCCCTGAA GAAGATGACC GTTGGGATGT TCCTGGCATC CATGGCCTTT 
GTGGTGGCTG CAATTGTGCA GGTGGAAATC GATAAAACTC TTCCAGTCTT CCCCAGCGGA 
AATCAAGTTC AAATTAAGGT CTTGAACATT GGAAACAATG ACATGGCCGT GTATTTTCCT 
GGAAAGAATG TGACAGTTGC CCAAATGTCT CAGACAGACA CATTCATGAC TTTCGATGTA 
GACCAGCTGA CAAGCATAAA CGTGTCTTCT CCCGGATCTC CAGGCGTCAC CACGGTAGCT 
CATGAGTTTG AGCCGGGTCA CCGGCACACC CTTCTAGTGT GGGGCCCCAA TCTATACCGT 
GTGGTAAAAG ACGGTCTTAA CCAAAAGCCA GAGAAAGGGG AGAACGGAAT CAGATTCGTC 
AGCACCCTTA ACGAGATGAT CACCATCAAA ATGAGTGGAA AAGTGTACGA AAATGTCACC 
AGTCACAGCG CCAGCAACTA CCAGTTTTTC CCTTCTGGCC AAAAAGACTA CACAATAAAC 
ACCACAGAGA TTGCACCAAA CTGTTCATCT GATTTTAAAT CTTCCAACCT TGACTTCGGC 
AGCGCGTACA CCTACGTGAT CAGAAGTAGG GCGAGTGATG GCTGCCTGGA AGTGAAGGAA 
TTCGAAGACA TCCCACCCAA CACGGTGAAC ATGGCCCTGC AGATCCCACA GTACTTCCTC 
CTCACCTGCG GCGAGGTGGT CTTCTCTGTC ACAGGACTGG AGTTCTCCTA TTCCCAGGCC 
CCGTCTAACA TGAAGTCCGT GCTTCAGGCA GGATGGCTTC TAACCGTGGC CATCGGTAAT 
ATCATTGTCC TCATTGTGGC TGAGGCAGGC CACTTCGACA AACAGTGGGC TGAGTATGTT 
CTGTTCGCCT CCTTGCTCCT GGTCGTCTGC ATCATATTTG CCATTATGGC CCGATTCTAC 
ACCTACATCA ACCCAGCAGA GATCGAGGCA CAGTTCGATG AGGATGAGAA GAAAAAGGGC 
GTAGGGAAGG AAAACCCGTA TTCCTCGTTG GAACCTGTCT CACAGACAAA CATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evaluation of PepT1 transport of food-derived antihypertensive peptides, Ile-Pro-Pro and Leu-Lys-Pro using in vitro, ex vivo and in vivo transport models.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V115276-284(2017 Jun)
Gleeson JP,Brayden DJ,Ryan SM

Ghrelin upregulates PepT1 activity in the small intestine epithelium of rats with sepsis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie86669-676(2017 Feb)
Liu J,Shi B,Shi K,Ma G,Zhang H,Lou X,Liu H,Wan S,Liang D

Nod2-Rip2 Signaling Contributes to Intestinal Injury Induced by Muramyl Dipeptide Via Oligopeptide Transporter in Rats.
Digestive diseases and sciences60(11)3264-70(2015 Nov)
Ma G,Shi B,Liu J,Zhang H,YinTao Z,Lou X,Liang D,Hou Y,Wan S,Yang W

Slc15a1 is involved in the transport of synthetic F5-peptide into the seminiferous epithelium in adult rat testes.
Scientific reports516271(2015 Nov)
Su L,Zhang Y,Cheng YC,Lee WM,Ye K,Hu D

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Slc15a1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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