BOLA2B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	BOLA2B
Entrez Gene ID	654483
Full Name	bolA family member 2B
Synonyms	BOLA2
General protein information	Preferred Names bolA family member 2B Names bolA-like protein 2 BolA-like protein 2 member B bolA homolog 2B bolA-like protein 2B
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16p11.2
Summary	This gene is located within a region of a segmental duplication on chromosome 16 and is identical to BOLA2 (bolA family member 2). The product of this gene belongs to a family of proteins that are widely conserved and may be involved in iron maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001320607.1	NP_001307536.1	bolA-like protein 2 isoform 2
NM_001039182.2	NP_001034271.1	bolA-like protein 2 isoform 1
NM_001039182.1	NP_001034271.1	bolA-like protein 2
NM_001039182.4	NP_001034271.2	bolA-like protein 2 isoform 1
NM_001320607.2	NP_001307536.2	bolA-like protein 2 isoform 2
NM_001039182.3	NP_001034271.2	bolA-like protein 2 isoform 1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	LOC100363408	XP_006250179.1
Homo sapiens (human)	BOLA2B	NP_001034271.1
	BOLA2	XP_001110082.1
Homo sapiens (human)	BOLA2	NP_001026997.1

Gene Ontology
Bibliography

Related articles in PubMed

A Glutaredoxin?BolA Complex Serves as an Iron-Sulfur Cluster Chaperone for the Cytosolic Cluster Assembly Machinery.
Frey AG, Palenchar DJ, Wildemann JD, Philpott CC
The Journal of biological chemistry291(43)22344-22356(2016 10)

Elucidating the Molecular Function of Human BOLA2 in GRX3-Dependent Anamorsin Maturation Pathway.
Banci L, Camponeschi F, Ciofi-Baffoni S, Muzzioli R
Journal of the American Chemical Society137(51)16133-43(2015 Dec)

BOLA1 is an aerobic protein that prevents mitochondrial morphology changes induced by glutathione depletion.
Willems P, Wanschers BF, Esseling J, Szklarczyk R, Kudla U, Duarte I, Forkink M, Nooteboom M, Swarts H, Gloerich J, Nijtmans L, Koopman W, Huynen MA
Antioxidants & redox signaling18(2)129-38(2013 Jan)

Human glutaredoxin 3 forms [2Fe-2S]-bridged complexes with human BolA2.
Li H, Mapolelo DT, Randeniya S, Johnson MK, Outten CE
Biochemistry51(8)1687-96(2012 Feb)

A census of human transcription factors: function, expression and evolution.
Vaquerizas JM, Kummerfeld SK, Teichmann SA, Luscombe NM
Nature reviews. Genetics10(4)252-63(2009 04)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following BOLA2B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BOLA2B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29006	NM_001039182.2 Latest version!	Homo sapiens bolA family member 2B (BOLA2B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu101964	NM_001320607.1 Latest version!	Homo sapiens bolA family member 2B (BOLA2B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu107097	NM_001039182.4 Latest version!	Homo sapiens bolA family member 2B (BOLA2B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu107101	NM_001320607.2 Latest version!	Homo sapiens bolA family member 2B (BOLA2B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu29006	NM_001039182.1	Homo sapiens bolA family member 2B (BOLA2B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu107097	NM_001039182.3	Homo sapiens bolA family member 2B (BOLA2B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

BOLA2B ( NM_001039182.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001034271.1 Homo sapiens bolA family member 2B (BOLA2B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu29006
Clone ID Related Accession (Same CDS sequence)	NM_001039182.2 , NM_001039182.1
Accession Version	NM_001039182.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 459bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	bolA-like protein 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC106782.5 and BC137532.1. On Mar 2, 2016 this sequence version replaced NM_001039182.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: HY043094.1, SRR1163655.446162.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAAGCG CGAAAAGCCT GGACCGCTGG AAAGCCCGGC TGCTTGAGGG CGGAAGTACT 
GCGTTGACGT ACGCCTTAGT AAGGGCGGAA GTGAGTTTTC CAGCGGAAGT GGCTCCTGTA 
AGGCAGCAAG GTAGCGTGGC CGGCGCCCGA GCTGGGGTTG TGTCCCTGCT GGGCTGCCGT 
TCCAGCTGGA CTGCCGCCAT GGAACTCAGC GCCGAATACC TCCGCGAGAA GCTGCAGCGG 
GACCTGGAGG CGGAGCATGT GGAGGTGGAG GACACGACCC TCAACCGTTG CTCCTGTAGC 
TTCCGAGTCC TGGTGGTGTC GGCCAAGTTC GAGGGGAAAC CGCTGCTTCA GAGACACAGG 
CTGGTGAACG CGTGCCTAGC AGAAGAGCTC CCGCACATCC ATGCCTTTGA ACAGAAAACC 
CTGACCCCAG ACCAGTGGGC ACGTGAGCGA CAGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034271.1
CDS	514..972
Translation	MASAKSLDRWKARLLEGGSTALTYALVRAEVSFPAEVAPVRQQGSVAGARAGVVSLLGCRSSWTAAMELSAEYLREKLQRDLEAEHVEVEDTTLNRCSCSFRVLVVSAKFEGKPLLQRHRLVNACLAEELPHIHAFEQKTLTPDQWARERQK

Target ORF information:

RefSeq Version	NM_001039182.2
Organism	Homo sapiens(human)
Definition	Homo sapiens bolA family member 2B (BOLA2B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039182.2

ORF Insert Sequence:

ATGGCAAGCG CGAAAAGCCT GGACCGCTGG AAAGCCCGGC TGCTTGAGGG CGGAAGTACT 
GCGTTGACGT ACGCCTTAGT AAGGGCGGAA GTGAGTTTTC CAGCGGAAGT GGCTCCTGTA 
AGGCAGCAAG GTAGCGTGGC CGGCGCCCGA GCTGGGGTTG TGTCCCTGCT GGGCTGCCGT 
TCCAGCTGGA CTGCCGCCAT GGAACTCAGC GCCGAATACC TCCGCGAGAA GCTGCAGCGG 
GACCTGGAGG CGGAGCATGT GGAGGTGGAG GACACGACCC TCAACCGTTG CTCCTGTAGC 
TTCCGAGTCC TGGTGGTGTC GGCCAAGTTC GAGGGGAAAC CGCTGCTTCA GAGACACAGG 
CTGGTGAACG CGTGCCTAGC AGAAGAGCTC CCGCACATCC ATGCCTTTGA ACAGAAAACC 
CTGACCCCAG ACCAGTGGGC ACGTGAGCGA CAGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BOLA2B ( NM_001039182.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001034271.1 Homo sapiens bolA family member 2B (BOLA2B), mRNA.

Price & Availability↑

CloneID	OHu29006
Clone ID Related Accession (Same CDS sequence)	NM_001039182.2 , NM_001039182.1
Accession Version	NM_001039182.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 459bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	bolA-like protein 2
Comment

ATGGCAAGCG CGAAAAGCCT GGACCGCTGG AAAGCCCGGC TGCTTGAGGG CGGAAGTACT 
GCGTTGACGT ACGCCTTAGT AAGGGCGGAA GTGAGTTTTC CAGCGGAAGT GGCTCCTGTA 
AGGCAGCAAG GTAGCGTGGC CGGCGCCCGA GCTGGGGTTG TGTCCCTGCT GGGCTGCCGT 
TCCAGCTGGA CTGCCGCCAT GGAACTCAGC GCCGAATACC TCCGCGAGAA GCTGCAGCGG 
GACCTGGAGG CGGAGCATGT GGAGGTGGAG GACACGACCC TCAACCGTTG CTCCTGTAGC 
TTCCGAGTCC TGGTGGTGTC GGCCAAGTTC GAGGGGAAAC CGCTGCTTCA GAGACACAGG 
CTGGTGAACG CGTGCCTAGC AGAAGAGCTC CCGCACATCC ATGCCTTTGA ACAGAAAACC 
CTGACCCCAG ACCAGTGGGC ACGTGAGCGA CAGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034271.1
Translation	MASAKSLDRWKARLLEGGSTALTYALVRAEVSFPAEVAPVRQQGSVAGARAGVVSLLGCRSSWTAAMELSAEYLREKLQRDLEAEHVEVEDTTLNRCSCSFRVLVVSAKFEGKPLLQRHRLVNACLAEELPHIHAFEQKTLTPDQWARERQK

Target ORF information:

RefSeq Version	NM_001039182.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens bolA family member 2B (BOLA2B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039182.1

ORF Insert Sequence:

ATGGCAAGCG CGAAAAGCCT GGACCGCTGG AAAGCCCGGC TGCTTGAGGG CGGAAGTACT 
GCGTTGACGT ACGCCTTAGT AAGGGCGGAA GTGAGTTTTC CAGCGGAAGT GGCTCCTGTA 
AGGCAGCAAG GTAGCGTGGC CGGCGCCCGA GCTGGGGTTG TGTCCCTGCT GGGCTGCCGT 
TCCAGCTGGA CTGCCGCCAT GGAACTCAGC GCCGAATACC TCCGCGAGAA GCTGCAGCGG 
GACCTGGAGG CGGAGCATGT GGAGGTGGAG GACACGACCC TCAACCGTTG CTCCTGTAGC 
TTCCGAGTCC TGGTGGTGTC GGCCAAGTTC GAGGGGAAAC CGCTGCTTCA GAGACACAGG 
CTGGTGAACG CGTGCCTAGC AGAAGAGCTC CCGCACATCC ATGCCTTTGA ACAGAAAACC 
CTGACCCCAG ACCAGTGGGC ACGTGAGCGA CAGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BOLA2B ( NM_001320607.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001307536.1 Homo sapiens bolA family member 2B (BOLA2B), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu101964
Clone ID Related Accession (Same CDS sequence)	NM_001320607.1
Accession Version	NM_001320607.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 372bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	bolA-like protein 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC106782.5 and BU960186.1. Transcript Variant: This variant (2) uses an alternate splice site, which results in a frameshift, compared to variant 1. The encoded isoform (2) has a distinct, shorter C-terminus than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BU960186.1, AI422657.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAAGCG CGAAAAGCCT GGACCGCTGG AAAGCCCGGC TGCTTGAGGG CGGAAGTACT 
GCGTTGACGT ACGCCTTAGT AAGGGCGGAA GTGAGTTTTC CAGCGGAAGT GGCTCCTGTA 
AGGCAGCAAG GTAGCGTGGC CGGCGCCCGA GCTGGGGTTG TGTCCCTGCT GGGCTGCCGT 
TCCAGCTGGA CTGCCGCCAT GGAACTCAGC GCCGAATACC TCCGCGAGAA GCTGCAGCGG 
GACCTGGAGG CGGAGCATGT GCTTCCGAGT CCTGGTGGTG TCGGCCAAGT TCGAGGGGAA 
ACCGCTGCTT CAGAGACACA GGCTGGTGAA CGCGTGCCTA GCAGAAGAGC TCCCGCACAT 
CCATGCCTTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001307536.1
CDS	514..885
Translation	MASAKSLDRWKARLLEGGSTALTYALVRAEVSFPAEVAPVRQQGSVAGARAGVVSLLGCRSSWTAAMELSAEYLREKLQRDLEAEHVLPSPGGVGQVRGETAASETQAGERVPSRRAPAHPCL

Target ORF information:

RefSeq Version	NM_001320607.1
Organism	Homo sapiens(human)
Definition	Homo sapiens bolA family member 2B (BOLA2B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001320607.1

ORF Insert Sequence:

ATGGCAAGCG CGAAAAGCCT GGACCGCTGG AAAGCCCGGC TGCTTGAGGG CGGAAGTACT 
GCGTTGACGT ACGCCTTAGT AAGGGCGGAA GTGAGTTTTC CAGCGGAAGT GGCTCCTGTA 
AGGCAGCAAG GTAGCGTGGC CGGCGCCCGA GCTGGGGTTG TGTCCCTGCT GGGCTGCCGT 
TCCAGCTGGA CTGCCGCCAT GGAACTCAGC GCCGAATACC TCCGCGAGAA GCTGCAGCGG 
GACCTGGAGG CGGAGCATGT GCTTCCGAGT CCTGGTGGTG TCGGCCAAGT TCGAGGGGAA 
ACCGCTGCTT CAGAGACACA GGCTGGTGAA CGCGTGCCTA GCAGAAGAGC TCCCGCACAT 
CCATGCCTTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BOLA2B ( NM_001039182.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001034271.2 Homo sapiens bolA family member 2B (BOLA2B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu107097
Clone ID Related Accession (Same CDS sequence)	NM_001039182.4 , NM_001039182.3
Accession Version	NM_001039182.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 261bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Homo sapiens(human)
Product	bolA-like protein 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC137532.1 and AC106782.5. On May 17, 2019 this sequence version replaced NM_001039182.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). CCDS Note: This CCDS was updated to trim the coding region at the 5' end, which reduces the protein size to 86aa. The update is supported by conservation and proteomics data. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.446162.1, SRR7410570.599686.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000651894.2/ ENSP00000498355.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAACTCA GCGCCGAATA CCTCCGCGAG AAGCTGCAGC GGGACCTGGA GGCGGAGCAT 
GTGGAGGTGG AGGACACGAC CCTCAACCGT TGCTCCTGTA GCTTCCGAGT CCTGGTGGTG 
TCGGCCAAGT TCGAGGGGAA ACCGCTGCTT CAGAGACACA GGCTGGTGAA CGCGTGCCTA 
GCAGAAGAGC TCCCGCACAT CCATGCCTTT GAACAGAAAA CCCTGACCCC AGACCAGTGG 
GCACGTGAGC GACAGAAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034271.2
CDS	72..332
Translation	MELSAEYLREKLQRDLEAEHVEVEDTTLNRCSCSFRVLVVSAKFEGKPLLQRHRLVNACLAEELPHIHAFEQKTLTPDQWARERQK

Target ORF information:

RefSeq Version	NM_001039182.4
Organism	Homo sapiens(human)
Definition	Homo sapiens bolA family member 2B (BOLA2B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039182.4

ORF Insert Sequence:

ATGGAACTCA GCGCCGAATA CCTCCGCGAG AAGCTGCAGC GGGACCTGGA GGCGGAGCAT 
GTGGAGGTGG AGGACACGAC CCTCAACCGT TGCTCCTGTA GCTTCCGAGT CCTGGTGGTG 
TCGGCCAAGT TCGAGGGGAA ACCGCTGCTT CAGAGACACA GGCTGGTGAA CGCGTGCCTA 
GCAGAAGAGC TCCCGCACAT CCATGCCTTT GAACAGAAAA CCCTGACCCC AGACCAGTGG 
GCACGTGAGC GACAGAAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BOLA2B ( NM_001039182.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001034271.2 Homo sapiens bolA family member 2B (BOLA2B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu107097
Clone ID Related Accession (Same CDS sequence)	NM_001039182.4 , NM_001039182.3
Accession Version	NM_001039182.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 261bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-26
Organism	Homo sapiens(human)
Product	bolA-like protein 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC137532.1 and AC106782.5. On Jul 3, 2018 this sequence version replaced NM_001039182.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). CCDS Note: This CCDS was updated to trim the coding region at the 5' end, which reduces the protein size to 86aa. The update is supported by conservation and proteomics data. ##Evidence-Data-START## Transcript exon combination :: BU566915.1, HY043094.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAACTCA GCGCCGAATA CCTCCGCGAG AAGCTGCAGC GGGACCTGGA GGCGGAGCAT 
GTGGAGGTGG AGGACACGAC CCTCAACCGT TGCTCCTGTA GCTTCCGAGT CCTGGTGGTG 
TCGGCCAAGT TCGAGGGGAA ACCGCTGCTT CAGAGACACA GGCTGGTGAA CGCGTGCCTA 
GCAGAAGAGC TCCCGCACAT CCATGCCTTT GAACAGAAAA CCCTGACCCC AGACCAGTGG 
GCACGTGAGC GACAGAAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034271.2
CDS	72..332
Translation	MELSAEYLREKLQRDLEAEHVEVEDTTLNRCSCSFRVLVVSAKFEGKPLLQRHRLVNACLAEELPHIHAFEQKTLTPDQWARERQK

Target ORF information:

RefSeq Version	NM_001039182.3
Organism	Homo sapiens(human)
Definition	Homo sapiens bolA family member 2B (BOLA2B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039182.3

ORF Insert Sequence:

ATGGAACTCA GCGCCGAATA CCTCCGCGAG AAGCTGCAGC GGGACCTGGA GGCGGAGCAT 
GTGGAGGTGG AGGACACGAC CCTCAACCGT TGCTCCTGTA GCTTCCGAGT CCTGGTGGTG 
TCGGCCAAGT TCGAGGGGAA ACCGCTGCTT CAGAGACACA GGCTGGTGAA CGCGTGCCTA 
GCAGAAGAGC TCCCGCACAT CCATGCCTTT GAACAGAAAA CCCTGACCCC AGACCAGTGG 
GCACGTGAGC GACAGAAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BOLA2B ( NM_001320607.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001307536.2 Homo sapiens bolA family member 2B (BOLA2B), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu107101
Clone ID Related Accession (Same CDS sequence)	NM_001320607.2
Accession Version	NM_001320607.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 174bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	bolA-like protein 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BU960186.1 and AC106782.5. On Jul 3, 2018 this sequence version replaced NM_001320607.1. Transcript Variant: This variant (2) uses an alternate splice site, which results in a frameshift, compared to variant 1. The encoded isoform (2) has a distinct, shorter C-terminus than isoform 1. ##Evidence-Data-START## Transcript exon combination :: BU960186.1, AI422657.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121

ATGGAACTCA GCGCCGAATA CCTCCGCGAG AAGCTGCAGC GGGACCTGGA GGCGGAGCAT 
GTGCTTCCGA GTCCTGGTGG TGTCGGCCAA GTTCGAGGGG AAACCGCTGC TTCAGAGACA 
CAGGCTGGTG AACGCGTGCC TAGCAGAAGA GCTCCCGCAC ATCCATGCCT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001307536.2
CDS	72..245
Translation	MELSAEYLREKLQRDLEAEHVLPSPGGVGQVRGETAASETQAGERVPSRRAPAHPCL

Target ORF information:

RefSeq Version	NM_001320607.2
Organism	Homo sapiens(human)
Definition	Homo sapiens bolA family member 2B (BOLA2B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001320607.2

ORF Insert Sequence:

1
61
121

ATGGAACTCA GCGCCGAATA CCTCCGCGAG AAGCTGCAGC GGGACCTGGA GGCGGAGCAT 
GTGCTTCCGA GTCCTGGTGG TGTCGGCCAA GTTCGAGGGG AAACCGCTGC TTCAGAGACA 
CAGGCTGGTG AACGCGTGCC TAGCAGAAGA GCTCCCGCAC ATCCATGCCT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A Glutaredoxin?BolA Complex Serves as an Iron-Sulfur Cluster Chaperone for the Cytosolic Cluster Assembly Machinery.
The Journal of biological chemistry291(43)22344-22356(2016 10)
Frey AG,Palenchar DJ,Wildemann JD,Philpott CC

Elucidating the Molecular Function of Human BOLA2 in GRX3-Dependent Anamorsin Maturation Pathway.
Journal of the American Chemical Society137(51)16133-43(2015 Dec)
Banci L,Camponeschi F,Ciofi-Baffoni S,Muzzioli R

BOLA1 is an aerobic protein that prevents mitochondrial morphology changes induced by glutathione depletion.
Antioxidants & redox signaling18(2)129-38(2013 Jan)
Willems P,Wanschers BF,Esseling J,Szklarczyk R,Kudla U,Duarte I,Forkink M,Nooteboom M,Swarts H,Gloerich J,Nijtmans L,Koopman W,Huynen MA

Human glutaredoxin 3 forms [2Fe-2S]-bridged complexes with human BolA2.
Biochemistry51(8)1687-96(2012 Feb)
Li H,Mapolelo DT,Randeniya S,Johnson MK,Outten CE

A census of human transcription factors: function, expression and evolution.
Nature reviews. Genetics10(4)252-63(2009 04)
Vaquerizas JM,Kummerfeld SK,Teichmann SA,Luscombe NM

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BOLA2B cDNA ORF clone, Homo sapiens(human)

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Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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