SEMG2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SEMG2
Entrez Gene ID	6407
Full Name	semenogelin II
Synonyms	SGII
General protein information	Preferred Names semenogelin II Names semenogelin-2 Semenogelin 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20q13.12
Summary	The secreted protein encoded by this gene is involved in the formation of a gel matrix that encases ejaculated spermatozoa. Proteolysis by the prostate-specific antigen (PSA) breaks down the gel matrix and allows the spermatozoa to move more freely. The encoded protein is found in lesser abundance than a similar semenogelin protein. An antibacterial activity has been found for a antimicrobial peptide isolated from this protein. The genes encoding these two semenogelin proteins are found in a cluster on chromosome 20. [provided by RefSeq, Jan 2015].
Disorder MIM:	182141

mRNA and Protein(s)

mRNA	Protein	Name
NM_003008.3	NP_002999.1	semenogelin-2 precursor
NM_003008.2	NP_002999.1	semenogelin-2 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	SEMG2	NP_002999.1
Pan troglodytes (chimpanzee)	SEMG2	NP_001009138.1
	SEMG2	NP_001162125.1

Gene Ontology
Bibliography

Related articles in PubMed

Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection.
Roan NR, M?ller JA, Liu H, Chu S, Arnold F, St?rzel CM, Walther P, Dong M, Witkowska HE, Kirchhoff F, M?nch J, Greene WC
Cell host & microbe10(6)541-50(2011 Dec)

Proteomic characterization of the human sperm nucleus.
de Mateo S, Castillo J, Estanyol JM, Ballesc? JL, Oliva R
Proteomics11(13)2714-26(2011 Jul)

Expression of semenogelins I and II and its prognostic significance in human prostate cancer.
Canacci AM, Izumi K, Zheng Y, Gordetsky J, Yao JL, Miyamoto H
The Prostate71(10)1108-14(2011 Jul)

Functional implications of membrane modification with semenogelins for inhibition of sperm motility in humans.
Yoshida K, Krasznai ZT, Krasznai Z, Yoshiike M, Kawano N, Yoshida M, Morisawa M, T?th Z, Bazs?n? ZK, M?ri?n T, Iwamoto T
Cell motility and the cytoskeleton66(2)99-108(2009 Feb)

The major bactericidal activity of human seminal plasma is zinc-dependent and derived from fragmentation of the semenogelins.
Edstr?m AM, Malm J, Frohm B, Martellini JA, Giwercman A, M?rgelin M, Cole AM, S?rensen OE
Journal of immunology (Baltimore, Md. : 1950)181(5)3413-21(2008 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Peptides released by physiological cleavage of Semg1 and Semg2 form amyloids that enhance HIV infection.
Title: Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection.

These results suggest the involvement of semenogelins in prostate cancer and their prognostic values in predicting cancer progression after radical prostatectomy.
Title: Expression of semenogelins I and II and its prognostic significance in human prostate cancer.

Semenogelins (Sgs) modifies the membrane structure, indirectly inhibiting motility, and provides suggestions for a therapy for male infertility through selection of a functional sperm population using Sgs.
Title: Functional implications of membrane modification with semenogelins for inhibition of sperm motility in humans.

antibacterial activity of the semenogelin-derived peptides generated in seminal plasma was strictly zinc-dependent both at neutral and low pH
Title: The major bactericidal activity of human seminal plasma is zinc-dependent and derived from fragmentation of the semenogelins.

semenogelins I and II were directly cleaved by KLK14. Semenogelins were also able to reverse KLK14 inhibition by Zn2+, providing a novel regulatory mechanism for KLK14 activity.
Title: Major role of human KLK14 in seminal clot liquefaction.

The following SEMG2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SEMG2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29302	NM_003008.3 Latest version!	Homo sapiens semenogelin 2 (SEMG2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
View Old Accession Versions >>
OHu29302	NM_003008.2	Homo sapiens semenogelin 2 (SEMG2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SEMG2 ( NM_003008.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002999.1 Homo sapiens semenogelin 2 (SEMG2), mRNA.

Price & Availability↑

CloneID	OHu29302
Clone ID Related Accession (Same CDS sequence)	NM_003008.3 , NM_003008.2
Accession Version	NM_003008.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1749bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	semenogelin-2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL049767.12. On May 17, 2019 this sequence version replaced NM_003008.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC070306.1, M81652.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03465411 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000372769.4/ ENSP00000361855.3 Protein has antimicrobial activity :: PMID: 18714013 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGTCCA TCATCCTCTT TGTCCTTTCC CTGCTCCTTA TCTTGGAGAA GCAAGCAGCT 
GTGATGGGAC AAAAAGGTGG ATCAAAAGGC CAATTGCCAA GCGGATCTTC CCAATTTCCA 
CATGGACAAA AGGGCCAGCA CTATTTTGGA CAAAAAGACC AACAACATAC TAAATCCAAA 
GGCAGTTTTT CTATTCAACA CACATATCAT GTAGACATCA ATGATCATGA CTGGACCCGA 
AAAAGTCAGC AATATGATTT GAATGCCCTA CATAAGGCGA CAAAATCAAA ACAACACCTA 
GGTGGAAGTC AACAACTGCT CAATTATAAA CAAGAAGGCA GAGACCATGA TAAATCAAAA 
GGTCATTTTC ACATGATAGT TATACATCAT AAAGGAGGCC AAGCTCATCA TGGGACACAA 
AATCCTTCTC AAGATCAGGG GAATAGCCCA TCTGGAAAGG GATTATCCAG TCAATGTTCA 
AACACAGAAA AAAGGCTATG GGTTCATGGA CTAAGTAAAG AACAAGCTTC AGCCTCTGGT 
GCACAAAAAG GTAGAACACA AGGTGGATCC CAAAGCAGTT ATGTTCTCCA AACTGAAGAA 
CTAGTAGTTA ACAAACAACA ACGTGAGACT AAAAATTCTC ATCAAAATAA AGGGCATTAC 
CAAAATGTGG TTGACGTGAG AGAGGAACAT TCAAGTAAAC TACAAACTTC ACTCCATCCT 
GCACATCAAG ACAGACTCCA ACATGGACCC AAAGACATTT TTACTACCCA AGATGAGCTC 
CTAGTATATA ACAAGAATCA ACACCAGACA AAAAATCTCA GTCAAGATCA AGAGCATGGC 
CGGAAGGCAC ATAAAATATC ATACCCGTCT TCACGTACAG AAGAAAGACA ACTTCACCAT 
GGAGAAAAGA GTGTACAGAA AGATGTATCC AAAGGCAGCA TTTCTATCCA AACTGAAGAG 
AAAATACATG GCAAGTCTCA AAACCAGGTA ACAATTCATA GTCAAGATCA AGAGCATGGC 
CATAAGGAAA ATAAAATATC ATACCAATCT TCAAGTACAG AAGAAAGACA TCTCAACTGT 
GGAGAAAAGG GCATCCAGAA AGGTGTATCC AAAGGCAGTA TTTCGATCCA AACTGAAGAG 
CAAATACATG GCAAGTCTCA AAACCAGGTA AGAATTCCTA GTCAAGCTCA AGAGTATGGC 
CATAAGGAAA ATAAAATATC ATACCAATCT TCGAGTACAG AAGAAAGACG TCTCAACAGT 
GGAGAAAAGG ATGTACAGAA AGGTGTATCC AAAGGCAGTA TTTCTATCCA AACTGAAGAG 
AAAATACATG GCAAGTCTCA AAACCAGGTA ACAATTCCTA GTCAAGATCA AGAGCATGGC 
CATAAGGAAA ATAAAATGTC ATACCAATCT TCAAGTACAG AAGAAAGACG ACTCAACTAT 
GGAGGAAAGA GCACGCAGAA AGATGTATCC CAAAGCAGTA TTTCTTTCCA AATTGAAAAG 
CTAGTAGAAG GCAAGTCTCA AATCCAGACA CCAAATCCTA ATCAAGATCA ATGGTCTGGC 
CAAAATGCAA AAGGAAAGTC TGGTCAATCT GCAGATAGCA AACAAGACCT ACTCAGTCAT 
GAACAAAAAG GCAGATACAA ACAGGAATCC AGTGAGTCAC ATAATATTGT AATTACTGAG 
CATGAGGTTG CCCAAGATGA TCATTTGACA CAACAATATA ATGAAGACAG AAATCCAATA 
TCTACATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002999.1
CDS	18..1766
Translation	MKSIILFVLSLLLILEKQAAVMGQKGGSKGQLPSGSSQFPHGQKGQHYFGQKDQQHTKSKGSFSIQHTYHVDINDHDWTRKSQQYDLNALHKATKSKQHLGGSQQLLNYKQEGRDHDKSKGHFHMIVIHHKGGQAHHGTQNPSQDQGNSPSGKGLSSQCSNTEKRLWVHGLSKEQASASGAQKGRTQGGSQSSYVLQTEELVVNKQQRETKNSHQNKGHYQNVVDVREEHSSKLQTSLHPAHQDRLQHGPKDIFTTQDELLVYNKNQHQTKNLSQDQEHGRKAHKISYPSSRTEERQLHHGEKSVQKDVSKGSISIQTEEKIHGKSQNQVTIHSQDQEHGHKENKISYQSSSTEERHLNCGEKGIQKGVSKGSISIQTEEQIHGKSQNQVRIPSQAQEYGHKENKISYQSSSTEERRLNSGEKDVQKGVSKGSISIQTEEKIHGKSQNQVTIPSQDQEHGHKENKMSYQSSSTEERRLNYGGKSTQKDVSQSSISFQIEKLVEGKSQIQTPNPNQDQWSGQNAKGKSGQSADSKQDLLSHEQKGRYKQESSESHNIVITEHEVAQDDHLTQQYNEDRNPIST

Target ORF information:

RefSeq Version	NM_003008.3
Organism	Homo sapiens(human)
Definition	Homo sapiens semenogelin 2 (SEMG2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003008.3

ORF Insert Sequence:

ATGAAGTCCA TCATCCTCTT TGTCCTTTCC CTGCTCCTTA TCTTGGAGAA GCAAGCAGCT 
GTGATGGGAC AAAAAGGTGG ATCAAAAGGC CAATTGCCAA GCGGATCTTC CCAATTTCCA 
CATGGACAAA AGGGCCAGCA CTATTTTGGA CAAAAAGACC AACAACATAC TAAATCCAAA 
GGCAGTTTTT CTATTCAACA CACATATCAT GTAGACATCA ATGATCATGA CTGGACCCGA 
AAAAGTCAGC AATATGATTT GAATGCCCTA CATAAGGCGA CAAAATCAAA ACAACACCTA 
GGTGGAAGTC AACAACTGCT CAATTATAAA CAAGAAGGCA GAGACCATGA TAAATCAAAA 
GGTCATTTTC ACATGATAGT TATACATCAT AAAGGAGGCC AAGCTCATCA TGGGACACAA 
AATCCTTCTC AAGATCAGGG GAATAGCCCA TCTGGAAAGG GATTATCCAG TCAATGTTCA 
AACACAGAAA AAAGGCTATG GGTTCATGGA CTAAGTAAAG AACAAGCTTC AGCCTCTGGT 
GCACAAAAAG GTAGAACACA AGGTGGATCC CAAAGCAGTT ATGTTCTCCA AACTGAAGAA 
CTAGTAGTTA ACAAACAACA ACGTGAGACT AAAAATTCTC ATCAAAATAA AGGGCATTAC 
CAAAATGTGG TTGACGTGAG AGAGGAACAT TCAAGTAAAC TACAAACTTC ACTCCATCCT 
GCACATCAAG ACAGACTCCA ACATGGACCC AAAGACATTT TTACTACCCA AGATGAGCTC 
CTAGTATATA ACAAGAATCA ACACCAGACA AAAAATCTCA GTCAAGATCA AGAGCATGGC 
CGGAAGGCAC ATAAAATATC ATACCCGTCT TCACGTACAG AAGAAAGACA ACTTCACCAT 
GGAGAAAAGA GTGTACAGAA AGATGTATCC AAAGGCAGCA TTTCTATCCA AACTGAAGAG 
AAAATACATG GCAAGTCTCA AAACCAGGTA ACAATTCATA GTCAAGATCA AGAGCATGGC 
CATAAGGAAA ATAAAATATC ATACCAATCT TCAAGTACAG AAGAAAGACA TCTCAACTGT 
GGAGAAAAGG GCATCCAGAA AGGTGTATCC AAAGGCAGTA TTTCGATCCA AACTGAAGAG 
CAAATACATG GCAAGTCTCA AAACCAGGTA AGAATTCCTA GTCAAGCTCA AGAGTATGGC 
CATAAGGAAA ATAAAATATC ATACCAATCT TCGAGTACAG AAGAAAGACG TCTCAACAGT 
GGAGAAAAGG ATGTACAGAA AGGTGTATCC AAAGGCAGTA TTTCTATCCA AACTGAAGAG 
AAAATACATG GCAAGTCTCA AAACCAGGTA ACAATTCCTA GTCAAGATCA AGAGCATGGC 
CATAAGGAAA ATAAAATGTC ATACCAATCT TCAAGTACAG AAGAAAGACG ACTCAACTAT 
GGAGGAAAGA GCACGCAGAA AGATGTATCC CAAAGCAGTA TTTCTTTCCA AATTGAAAAG 
CTAGTAGAAG GCAAGTCTCA AATCCAGACA CCAAATCCTA ATCAAGATCA ATGGTCTGGC 
CAAAATGCAA AAGGAAAGTC TGGTCAATCT GCAGATAGCA AACAAGACCT ACTCAGTCAT 
GAACAAAAAG GCAGATACAA ACAGGAATCC AGTGAGTCAC ATAATATTGT AATTACTGAG 
CATGAGGTTG CCCAAGATGA TCATTTGACA CAACAATATA ATGAAGACAG AAATCCAATA 
TCTACATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SEMG2 ( NM_003008.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_002999.1 Homo sapiens semenogelin 2 (SEMG2), mRNA.

Price & Availability↑

CloneID	OHu29302
Clone ID Related Accession (Same CDS sequence)	NM_003008.3 , NM_003008.2
Accession Version	NM_003008.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1749bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Homo sapiens(human)
Product	semenogelin-2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M81652.1. On Oct 30, 2003 this sequence version replaced NM_003008.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK291811.1, M81652.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03465411 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## Protein has antimicrobial activity :: PMID: 18714013 ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGTCCA TCATCCTCTT TGTCCTTTCC CTGCTCCTTA TCTTGGAGAA GCAAGCAGCT 
GTGATGGGAC AAAAAGGTGG ATCAAAAGGC CAATTGCCAA GCGGATCTTC CCAATTTCCA 
CATGGACAAA AGGGCCAGCA CTATTTTGGA CAAAAAGACC AACAACATAC TAAATCCAAA 
GGCAGTTTTT CTATTCAACA CACATATCAT GTAGACATCA ATGATCATGA CTGGACCCGA 
AAAAGTCAGC AATATGATTT GAATGCCCTA CATAAGGCGA CAAAATCAAA ACAACACCTA 
GGTGGAAGTC AACAACTGCT CAATTATAAA CAAGAAGGCA GAGACCATGA TAAATCAAAA 
GGTCATTTTC ACATGATAGT TATACATCAT AAAGGAGGCC AAGCTCATCA TGGGACACAA 
AATCCTTCTC AAGATCAGGG GAATAGCCCA TCTGGAAAGG GATTATCCAG TCAATGTTCA 
AACACAGAAA AAAGGCTATG GGTTCATGGA CTAAGTAAAG AACAAGCTTC AGCCTCTGGT 
GCACAAAAAG GTAGAACACA AGGTGGATCC CAAAGCAGTT ATGTTCTCCA AACTGAAGAA 
CTAGTAGTTA ACAAACAACA ACGTGAGACT AAAAATTCTC ATCAAAATAA AGGGCATTAC 
CAAAATGTGG TTGACGTGAG AGAGGAACAT TCAAGTAAAC TACAAACTTC ACTCCATCCT 
GCACATCAAG ACAGACTCCA ACATGGACCC AAAGACATTT TTACTACCCA AGATGAGCTC 
CTAGTATATA ACAAGAATCA ACACCAGACA AAAAATCTCA GTCAAGATCA AGAGCATGGC 
CGGAAGGCAC ATAAAATATC ATACCCGTCT TCACGTACAG AAGAAAGACA ACTTCACCAT 
GGAGAAAAGA GTGTACAGAA AGATGTATCC AAAGGCAGCA TTTCTATCCA AACTGAAGAG 
AAAATACATG GCAAGTCTCA AAACCAGGTA ACAATTCATA GTCAAGATCA AGAGCATGGC 
CATAAGGAAA ATAAAATATC ATACCAATCT TCAAGTACAG AAGAAAGACA TCTCAACTGT 
GGAGAAAAGG GCATCCAGAA AGGTGTATCC AAAGGCAGTA TTTCGATCCA AACTGAAGAG 
CAAATACATG GCAAGTCTCA AAACCAGGTA AGAATTCCTA GTCAAGCTCA AGAGTATGGC 
CATAAGGAAA ATAAAATATC ATACCAATCT TCGAGTACAG AAGAAAGACG TCTCAACAGT 
GGAGAAAAGG ATGTACAGAA AGGTGTATCC AAAGGCAGTA TTTCTATCCA AACTGAAGAG 
AAAATACATG GCAAGTCTCA AAACCAGGTA ACAATTCCTA GTCAAGATCA AGAGCATGGC 
CATAAGGAAA ATAAAATGTC ATACCAATCT TCAAGTACAG AAGAAAGACG ACTCAACTAT 
GGAGGAAAGA GCACGCAGAA AGATGTATCC CAAAGCAGTA TTTCTTTCCA AATTGAAAAG 
CTAGTAGAAG GCAAGTCTCA AATCCAGACA CCAAATCCTA ATCAAGATCA ATGGTCTGGC 
CAAAATGCAA AAGGAAAGTC TGGTCAATCT GCAGATAGCA AACAAGACCT ACTCAGTCAT 
GAACAAAAAG GCAGATACAA ACAGGAATCC AGTGAGTCAC ATAATATTGT AATTACTGAG 
CATGAGGTTG CCCAAGATGA TCATTTGACA CAACAATATA ATGAAGACAG AAATCCAATA 
TCTACATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002999.1
CDS	22..1770
Translation	MKSIILFVLSLLLILEKQAAVMGQKGGSKGQLPSGSSQFPHGQKGQHYFGQKDQQHTKSKGSFSIQHTYHVDINDHDWTRKSQQYDLNALHKATKSKQHLGGSQQLLNYKQEGRDHDKSKGHFHMIVIHHKGGQAHHGTQNPSQDQGNSPSGKGLSSQCSNTEKRLWVHGLSKEQASASGAQKGRTQGGSQSSYVLQTEELVVNKQQRETKNSHQNKGHYQNVVDVREEHSSKLQTSLHPAHQDRLQHGPKDIFTTQDELLVYNKNQHQTKNLSQDQEHGRKAHKISYPSSRTEERQLHHGEKSVQKDVSKGSISIQTEEKIHGKSQNQVTIHSQDQEHGHKENKISYQSSSTEERHLNCGEKGIQKGVSKGSISIQTEEQIHGKSQNQVRIPSQAQEYGHKENKISYQSSSTEERRLNSGEKDVQKGVSKGSISIQTEEKIHGKSQNQVTIPSQDQEHGHKENKMSYQSSSTEERRLNYGGKSTQKDVSQSSISFQIEKLVEGKSQIQTPNPNQDQWSGQNAKGKSGQSADSKQDLLSHEQKGRYKQESSESHNIVITEHEVAQDDHLTQQYNEDRNPIST

Target ORF information:

RefSeq Version	NM_003008.2
Organism	Homo sapiens(human)
Definition	Homo sapiens semenogelin 2 (SEMG2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003008.2

ORF Insert Sequence:

ATGAAGTCCA TCATCCTCTT TGTCCTTTCC CTGCTCCTTA TCTTGGAGAA GCAAGCAGCT 
GTGATGGGAC AAAAAGGTGG ATCAAAAGGC CAATTGCCAA GCGGATCTTC CCAATTTCCA 
CATGGACAAA AGGGCCAGCA CTATTTTGGA CAAAAAGACC AACAACATAC TAAATCCAAA 
GGCAGTTTTT CTATTCAACA CACATATCAT GTAGACATCA ATGATCATGA CTGGACCCGA 
AAAAGTCAGC AATATGATTT GAATGCCCTA CATAAGGCGA CAAAATCAAA ACAACACCTA 
GGTGGAAGTC AACAACTGCT CAATTATAAA CAAGAAGGCA GAGACCATGA TAAATCAAAA 
GGTCATTTTC ACATGATAGT TATACATCAT AAAGGAGGCC AAGCTCATCA TGGGACACAA 
AATCCTTCTC AAGATCAGGG GAATAGCCCA TCTGGAAAGG GATTATCCAG TCAATGTTCA 
AACACAGAAA AAAGGCTATG GGTTCATGGA CTAAGTAAAG AACAAGCTTC AGCCTCTGGT 
GCACAAAAAG GTAGAACACA AGGTGGATCC CAAAGCAGTT ATGTTCTCCA AACTGAAGAA 
CTAGTAGTTA ACAAACAACA ACGTGAGACT AAAAATTCTC ATCAAAATAA AGGGCATTAC 
CAAAATGTGG TTGACGTGAG AGAGGAACAT TCAAGTAAAC TACAAACTTC ACTCCATCCT 
GCACATCAAG ACAGACTCCA ACATGGACCC AAAGACATTT TTACTACCCA AGATGAGCTC 
CTAGTATATA ACAAGAATCA ACACCAGACA AAAAATCTCA GTCAAGATCA AGAGCATGGC 
CGGAAGGCAC ATAAAATATC ATACCCGTCT TCACGTACAG AAGAAAGACA ACTTCACCAT 
GGAGAAAAGA GTGTACAGAA AGATGTATCC AAAGGCAGCA TTTCTATCCA AACTGAAGAG 
AAAATACATG GCAAGTCTCA AAACCAGGTA ACAATTCATA GTCAAGATCA AGAGCATGGC 
CATAAGGAAA ATAAAATATC ATACCAATCT TCAAGTACAG AAGAAAGACA TCTCAACTGT 
GGAGAAAAGG GCATCCAGAA AGGTGTATCC AAAGGCAGTA TTTCGATCCA AACTGAAGAG 
CAAATACATG GCAAGTCTCA AAACCAGGTA AGAATTCCTA GTCAAGCTCA AGAGTATGGC 
CATAAGGAAA ATAAAATATC ATACCAATCT TCGAGTACAG AAGAAAGACG TCTCAACAGT 
GGAGAAAAGG ATGTACAGAA AGGTGTATCC AAAGGCAGTA TTTCTATCCA AACTGAAGAG 
AAAATACATG GCAAGTCTCA AAACCAGGTA ACAATTCCTA GTCAAGATCA AGAGCATGGC 
CATAAGGAAA ATAAAATGTC ATACCAATCT TCAAGTACAG AAGAAAGACG ACTCAACTAT 
GGAGGAAAGA GCACGCAGAA AGATGTATCC CAAAGCAGTA TTTCTTTCCA AATTGAAAAG 
CTAGTAGAAG GCAAGTCTCA AATCCAGACA CCAAATCCTA ATCAAGATCA ATGGTCTGGC 
CAAAATGCAA AAGGAAAGTC TGGTCAATCT GCAGATAGCA AACAAGACCT ACTCAGTCAT 
GAACAAAAAG GCAGATACAA ACAGGAATCC AGTGAGTCAC ATAATATTGT AATTACTGAG 
CATGAGGTTG CCCAAGATGA TCATTTGACA CAACAATATA ATGAAGACAG AAATCCAATA 
TCTACATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection.
Cell host & microbe10(6)541-50(2011 Dec)
Roan NR,M?ller JA,Liu H,Chu S,Arnold F,St?rzel CM,Walther P,Dong M,Witkowska HE,Kirchhoff F,M?nch J,Greene WC

Proteomic characterization of the human sperm nucleus.
Proteomics11(13)2714-26(2011 Jul)
de Mateo S,Castillo J,Estanyol JM,Ballesc? JL,Oliva R

Expression of semenogelins I and II and its prognostic significance in human prostate cancer.
The Prostate71(10)1108-14(2011 Jul)
Canacci AM,Izumi K,Zheng Y,Gordetsky J,Yao JL,Miyamoto H

Functional implications of membrane modification with semenogelins for inhibition of sperm motility in humans.
Cell motility and the cytoskeleton66(2)99-108(2009 Feb)
Yoshida K,Krasznai ZT,Krasznai Z,Yoshiike M,Kawano N,Yoshida M,Morisawa M,T?th Z,Bazs?n? ZK,M?ri?n T,Iwamoto T

The major bactericidal activity of human seminal plasma is zinc-dependent and derived from fragmentation of the semenogelins.
Journal of immunology (Baltimore, Md. : 1950)181(5)3413-21(2008 Sep)
Edstr?m AM,Malm J,Frohm B,Martellini JA,Giwercman A,M?rgelin M,Cole AM,S?rensen OE

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SEMG2 cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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