OR2S2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	OR2S2
Entrez Gene ID	56656
Full Name	olfactory receptor family 2 subfamily S member 2 (gene/pseudogene)
Synonyms	OR37A,OST715
General protein information	Preferred Names olfactory receptor family 2 subfamily S member 2 (gene/pseudogene) Names olfactory receptor 2S2 olfactory receptor OR9-3 olfactory receptor, family 2, subfamily S, member 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9p13.3
Summary	Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jul 2015].

mRNA and Protein(s)

mRNA	Protein	Name
NM_019897.2	NP_063950.2	olfactory receptor 2S2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	LOC609676	XP_852074.2
Mus musculus (house mouse)	Olfr155	NP_062346.1
Rattus norvegicus (Norway rat)	Olr840	NP_001000414.1
Homo sapiens (human)	OR2S2	NP_063950.2
Pan troglodytes (chimpanzee)	OR2S2	XP_528597.2
	LOC100428848	XP_002800108.1
Canis lupus familiaris (dog)	LOC611974	XP_854786.1
Bos taurus (cattle)	OR2S2	XP_002689756.1

Gene Ontology
Bibliography

Related articles in PubMed

Personal receptor repertoires: olfaction as a model.
Olender T, Waszak SM, Viavant M, Khen M, Ben-Asher E, Reyes A, Nativ N, Wysocki CJ, Ge D, Lancet D
BMC genomics13414(2012 Aug)

An approach based on a genome-wide association study reveals candidate loci for narcolepsy.
Shimada M, Miyagawa T, Kawashima M, Tanaka S, Honda Y, Honda M, Tokunaga K
Human genetics128(4)433-41(2010 Oct)

A probabilistic classifier for olfactory receptor pseudogenes.
Menashe I, Aloni R, Lancet D
BMC bioinformatics7393(2006 Aug)

The human olfactory receptor gene family.
Malnic B, Godfrey PA, Buck LB
Proceedings of the National Academy of Sciences of the United States of America101(8)2584-9(2004 Feb)

Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human.
Hoppe R, Breer H, Strotmann J
Genomics82(3)355-64(2003 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: An approach based on a genome-wide association study reveals candidate loci for narcolepsy.

The following OR2S2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the OR2S2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu31322	NM_019897.2 Latest version!	Homo sapiens olfactory receptor family 2 subfamily S member 2 (gene/pseudogene) (OR2S2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

OR2S2 ( NM_019897.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_063950.2 Homo sapiens olfactory receptor family 2 subfamily S member 2 (gene/pseudogene) (OR2S2), mRNA.

Price & Availability↑

CloneID	OHu31322
Clone ID Related Accession (Same CDS sequence)	NM_019897.2
Accession Version	NM_019897.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 960bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Homo sapiens(human)
Product	olfactory receptor 2S2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC104869.1. On Feb 14, 2008 this sequence version replaced NM_019897.1. Sequence Note: This gene is a segregating pseudogene. This RefSeq represents the protein encoded by the reference genome allele, which is predicted to be functional according to the Classifier for Olfactory Receptor Pseudogenes. CCDS Note: This olfactory receptor gene is a segregating pseudogene (PMID:22908908), where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele that is predicted to be non-functional. This CCDS is being retained because the Classifier for Olfactory Receptor Pseudogenes (CORP) predicts the reference genome allele to be functional. ##Evidence-Data-START## Transcript is intronless :: BC104869.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000341959.2/ ENSP00000344040.2 polymorphic pseudogene :: PMID: 22908908 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGGAAAAAG CCAATGAGAC CTCCCCTGTG ATGGGGTTCG TTCTCCTGAG GCTCTCTGCC 
CACCCAGAGC TGGAAAAGAC ATTCTTCGTG CTCATCCTGC TGATGTACCT CGTGATCCTG 
CTGGGCAATG GGGTCCTCAT CCTGGTGACC ATCCTTGACT CCCGCCTGCA CACGCCCATG 
TACTTCTTCC TAGGGAACCT CTCCTTCCTG GACATCTGCT TCACTACCTC CTCAGTCCCA 
CTGGTCCTGG ACAGCTTTTT GACTCCCCAG GAAACCATCT CCTTCTCAGC CTGTGCTGTG 
CAGATGGCAC TCTCCTTTGC CATGGCAGGA ACAGAGTGCT TGCTCCTGAG CATGATGGCA 
TTTGATCGCT ATGTGGCCAT CTGCAACCCC CTTAGGTACT CCGTGATCAT GAGCAAGGCT 
GCCTACATGC CCATGGCTGC CAGCTCCTGG GCTATTGGTG GTGCTGCTTC CGTGGTACAC 
ACATCCTTGG CAATTCAGCT GCCCTTCTGT GGAGACAATG TCATCAACCA CTTCACCTGT 
GAGATTCTGG CTGTTCTAAA GTTGGCCTGT GCTGACATTT CCATCAATGT GATCAGCATG 
GAGGTGACGA ATGTGATCTT CCTAGGAGTC CCGGTTCTGT TCATCTCTTT CTCCTATGTC 
TTCATCATCA CCACCATCCT GAGGATCCCC TCAGCTGAGG GGAGGAAAAA GGTCTTCTCC 
ACCTGCTCTG CCCACCTCAC CGTGGTGATC GTCTTCTACG GGACCTTATT CTTCATGTAT 
GGGAAGCCTA AGTCTAAGGA CTCCATGGGA GCAGACAAAG AGGATCTTTC AGACAAACTC 
ATCCCCCTTT TCTATGGGGT GGTGACCCCG ATGCTCAACC CCATCATCTA TAGCCTGAGG 
AACAAGGATG TGAAGGCTGC TGTGAGGAGA CTGCTGAGAC CAAAAGGCTT CACTCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_063950.2
CDS	57..1016
Translation	MEKANETSPVMGFVLLRLSAHPELEKTFFVLILLMYLVILLGNGVLILVTILDSRLHTPMYFFLGNLSFLDICFTTSSVPLVLDSFLTPQETISFSACAVQMALSFAMAGTECLLLSMMAFDRYVAICNPLRYSVIMSKAAYMPMAASSWAIGGAASVVHTSLAIQLPFCGDNVINHFTCEILAVLKLACADISINVISMEVTNVIFLGVPVLFISFSYVFIITTILRIPSAEGRKKVFSTCSAHLTVVIVFYGTLFFMYGKPKSKDSMGADKEDLSDKLIPLFYGVVTPMLNPIIYSLRNKDVKAAVRRLLRPKGFTQ

Target ORF information:

RefSeq Version	NM_019897.2
Organism	Homo sapiens(human)
Definition	Homo sapiens olfactory receptor family 2 subfamily S member 2 (gene/pseudogene) (OR2S2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019897.2

ORF Insert Sequence:

ATGGAAAAAG CCAATGAGAC CTCCCCTGTG ATGGGGTTCG TTCTCCTGAG GCTCTCTGCC 
CACCCAGAGC TGGAAAAGAC ATTCTTCGTG CTCATCCTGC TGATGTACCT CGTGATCCTG 
CTGGGCAATG GGGTCCTCAT CCTGGTGACC ATCCTTGACT CCCGCCTGCA CACGCCCATG 
TACTTCTTCC TAGGGAACCT CTCCTTCCTG GACATCTGCT TCACTACCTC CTCAGTCCCA 
CTGGTCCTGG ACAGCTTTTT GACTCCCCAG GAAACCATCT CCTTCTCAGC CTGTGCTGTG 
CAGATGGCAC TCTCCTTTGC CATGGCAGGA ACAGAGTGCT TGCTCCTGAG CATGATGGCA 
TTTGATCGCT ATGTGGCCAT CTGCAACCCC CTTAGGTACT CCGTGATCAT GAGCAAGGCT 
GCCTACATGC CCATGGCTGC CAGCTCCTGG GCTATTGGTG GTGCTGCTTC CGTGGTACAC 
ACATCCTTGG CAATTCAGCT GCCCTTCTGT GGAGACAATG TCATCAACCA CTTCACCTGT 
GAGATTCTGG CTGTTCTAAA GTTGGCCTGT GCTGACATTT CCATCAATGT GATCAGCATG 
GAGGTGACGA ATGTGATCTT CCTAGGAGTC CCGGTTCTGT TCATCTCTTT CTCCTATGTC 
TTCATCATCA CCACCATCCT GAGGATCCCC TCAGCTGAGG GGAGGAAAAA GGTCTTCTCC 
ACCTGCTCTG CCCACCTCAC CGTGGTGATC GTCTTCTACG GGACCTTATT CTTCATGTAT 
GGGAAGCCTA AGTCTAAGGA CTCCATGGGA GCAGACAAAG AGGATCTTTC AGACAAACTC 
ATCCCCCTTT TCTATGGGGT GGTGACCCCG ATGCTCAACC CCATCATCTA TAGCCTGAGG 
AACAAGGATG TGAAGGCTGC TGTGAGGAGA CTGCTGAGAC CAAAAGGCTT CACTCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Personal receptor repertoires: olfaction as a model.
BMC genomics13414(2012 Aug)
Olender T,Waszak SM,Viavant M,Khen M,Ben-Asher E,Reyes A,Nativ N,Wysocki CJ,Ge D,Lancet D

An approach based on a genome-wide association study reveals candidate loci for narcolepsy.
Human genetics128(4)433-41(2010 Oct)
Shimada M,Miyagawa T,Kawashima M,Tanaka S,Honda Y,Honda M,Tokunaga K

A probabilistic classifier for olfactory receptor pseudogenes.
BMC bioinformatics7393(2006 Aug)
Menashe I,Aloni R,Lancet D

The human olfactory receptor gene family.
Proceedings of the National Academy of Sciences of the United States of America101(8)2584-9(2004 Feb)
Malnic B,Godfrey PA,Buck LB

Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human.
Genomics82(3)355-64(2003 Sep)
Hoppe R,Breer H,Strotmann J

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OR2S2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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