PANK4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PANK4
Entrez Gene ID	55229
Full Name	pantothenate kinase 4
General protein information	Preferred Names pantothenate kinase 4 Names pantothenate kinase 4 hPanK4 pantothenic acid kinase 4
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p36.32
Summary	This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is most abundant in muscle but is expressed in all tissues. [provided by RefSeq, Jul 2008].
Disorder MIM:	606162

mRNA and Protein(s)

mRNA	Protein	Name
XM_011541708.2	XP_011540010.2	pantothenate kinase 4 isoform X2
NM_018216.2	NP_060686.2	pantothenate kinase 4
NM_018216.4	NP_060686.3	4'-phosphopantetheine phosphatase
XM_011541708.3	XP_011540010.2	4'-phosphopantetheine phosphatase isoform X1
NM_018216.3	NP_060686.3	pantothenate kinase 4
XM_017001633.1	XP_016857122.1	pantothenate kinase 4 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	PANK4	NP_060686.1
Rattus norvegicus (Norway rat)	Pank4	NP_598215.1
Caenorhabditis elegans (roundworm)	pnk-4	NP_508866.1
Eremothecium gossypii	AGOS_AFR729C	NP_986277.2
Oryza sativa (rice)	Os09g0533100	NP_001063766.1
Canis lupus familiaris (dog)	PANK4	XP_536718.2
Bos taurus (cattle)	PANK4	NP_001076898.1
Gallus gallus (chicken)	PANK4	NP_001231841.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010073	XP_319230.4
Kluyveromyces lactis	KLLA0C00869g	XP_452233.1
Neurospora crassa	NCU03154	XP_964560.1
Xenopus tropicalis (tropical clawed frog)	pank4	NP_001120490.2
Pan troglodytes (chimpanzee)	PANK4	XP_524846.3
Mus musculus (house mouse)	Pank4	NP_766578.2
Saccharomyces cerevisiae (baker's yeast)	CAB1	NP_010820.3
	PANK4	XP_001086116.2
Danio rerio (zebrafish)	pank4	NP_956809.1
Drosophila melanogaster (fruit fly)	CG5828	NP_001260085.1
Schizosaccharomyces pombe (fission yeast)	SPBC4B4.01c	NP_596418.1
Magnaporthe oryzae (rice blast fungus)	MGG_17976	XP_003721002.1
Arabidopsis thaliana (thale cress)	PANK2	NP_194945.3

Gene Ontology
Bibliography

Related articles in PubMed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
Comuzzie AG, Cole SA, Laston SL, Voruganti VS, Haack K, Gibbs RA, Butte NF
PloS one7(12)e51954(2012)

High glucose upregulates pantothenate kinase 4 (PanK4) and thus affects M2-type pyruvate kinase (Pkm2).
Li Y, Chang Y, Zhang L, Feng Q, Liu Z, Zhang Y, Zuo J, Meng Y, Fang F
Molecular and cellular biochemistry277(1-2)117-25(2005 Sep)

A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome.
Zhou B, Westaway SK, Levinson B, Johnson MA, Gitschier J, Hayflick SJ
Nature genetics28(4)345-9(2001 Aug)

Coenzyme A metabolism.
Robishaw JD, Neely JR
The American journal of physiology248(1 Pt 1)E1-9(1985 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

PanK4 interacts with Pkm2 and thereby may modulate the glucose metabolism through regulating the activity of Pkm2.
Title: High glucose upregulates pantothenate kinase 4 (PanK4) and thus affects M2-type pyruvate kinase (Pkm2).

Observational study of gene-disease association. (HuGE Navigator)
Title: [Screening susceptibility genes of type 2 diabetes in Chinese population by single nucleotide polymorphism analysis].

The following PANK4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PANK4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu69198	NM_018216.2 Latest version!	Homo sapiens pantothenate kinase 4 (PANK4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu90181	XM_011541708.3 Latest version!	Homo sapiens pantothenate kinase 4 (inactive) (PANK4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu107068	NM_018216.4 Latest version!	Homo sapiens pantothenate kinase 4 (inactive) (PANK4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu90180	XM_017001633.1 Latest version!	Homo sapiens pantothenate kinase 4 (PANK4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu90181	XM_011541708.2	Homo sapiens pantothenate kinase 4 (PANK4), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu107068	NM_018216.3	Homo sapiens pantothenate kinase 4 (PANK4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PANK4 ( NM_018216.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_060686.2 Homo sapiens pantothenate kinase 4 (PANK4), mRNA.

Price & Availability↑

CloneID	OHu69198
Clone ID Related Accession (Same CDS sequence)	NM_018216.2
Accession Version	NM_018216.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2346bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-27
Organism	Homo sapiens(human)
Product	pantothenate kinase 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC327227.1, DC316156.1, AK001644.1 and AI301430.1. On Dec 16, 2014 this sequence version replaced NM_018216.1. ##Evidence-Data-START## Transcript exon combination :: AK295301.1, AK001644.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCTGGC CGGGCACTTT CAAAATGGCG GAGTGTGGAG CGAGCGGCAG CGGGAGCAGC 
GGGGACAGTC TGGACAAGAG CATCACGCTG CCCCCCGACG AGATCTTCCG CAACCTGGAG 
AACGCCAAGC GCTTCGCCAT CGACATAGGC GGGTCGTTAA CCAAGCTGGC CTACTATTCA 
ACGGTACAGC ACAAAGTCGC CAAGGTGCGG TCTTTCGACC ACTCCGGAAA GGACACAGAA 
CGTGAACATG AGCCGCCCTA TGAGATTTCA GTTCAAGAAG AGATCACTGC TCGACTGCAC 
TTCATTAAGT TTGAGAATAC CTACATCGAA GCCTGCCTGG ACTTCATCAA AGACCATCTC 
GTCAACACAG AGACCAAGGT CATCCAGGCG ACCGGGGGCG GGGCCTACAA GTTCAAAGAC 
CTCATCGAAG AGAAGCTGCG GCTGAAAGTC GACAAGGAGG ACGTGATGAC GTGCCTGATT 
AAGGGGTGCA ACTTCGTGCT CAAGAACATC CCCCATGAGG CCTTCGTGTA CCAGAAGGAT 
TCCGACCCTG AGTTCCGGTT CCAGACCAAC CACCCCCACA TTTTCCCCTA TCTTCTTGTC 
AATATCGGCT CTGGAGTCTC CATCGTGAAG GTGGAGACGG AGGACAGGTT CGAGTGGGTC 
GGCGGCAGCT CCATTGGAGG CGGCACCTTC TGGGGGCTTG GCGCTCTGCT CACCAAAACG 
AAGAAGTTTG ACGAGCTCCT GCACCTGGCC TCGAGGGGCC AGCACAGCAA TGTGGACATG 
CTGGTGCGGG ACGTCTACGG CGGCGCCCAC CAGACTCTCG GGCTGAGCGG GAACCTCATC 
GCCAGCAGCT TCGGGAAGTC GGCCACCGCC GACCAAGAGT TCTCCAAAGA AGACATGGCG 
AAGAGCCTGC TGCACATGAT CAGCAACGAC ATTGGGCAGC TGGCCTGCCT CCACGCACGG 
CTGCACAGCC TGGACCGCGT GTACTTTGGA GGCTTCTTTA TCCGGGGCCA CCCCGTGACC 
ATGCGCACCA TCACCTATAG CATCAACTTC TTCTCCAAGG GGGAAGTGCA GGCGCTGTTT 
CTGAGGCACG AAGGCTACCT GGGAGCCATC GGAGCGTTCC TGAAAGGAGC TGAGCAGGAC 
AATCCTAACC AGTACAGCTG GGGAGAGAAC TATGCAGGCA GCTCCGGGCT GATGAGTGCA 
TCACCCGAGC TCGGCCCGGC GCAGCGGGCG CGGAGTGGCA CTTTTGACTT GCTGGAAATG 
GACCGGCTGG AGAGGCCACT GGTTGACCTG CCGCTCCTCC TGGACCCGCC CTCCTACGTG 
CCCGACACGG TGGACCTCAC CGATGACGCT CTGGCCCGAA AATACTGGCT CACCTGCTTT 
GAGGAGGCCC TGGACGGGGT AGTGAAGCGC GCAGTGGCGA GCCAGCCAGA CTCTGTGGAT 
GCAGCCGAGA GGGCGGAGAA GTTCCGGCAG AAGTACTGGA ACAAGCTTCA GACCCTGAGG 
CAGCAGCCCT TCGCCTATGG GACCCTGACC GTGCGCAGCC TGCTGGACAC CAGGGAGCAC 
TGTCTGAACG AGTTCAACTT CCCGGATCCC TACTCCAAAG TGAAGCAGCG GGAGAATGGC 
GTGGCGCTGA GGTGCTTCCC CGGGGTCGTG CGCTCCCTGG ACGCGCTGGG CTGGGAGGAA 
CGGCAGCTGG CGCTGGTGAA AGGCCTCCTG GCGGGGAATG TCTTCGACTG GGGGGCCAAA 
GCCGTGTCTG CTGTCCTTGA ATCCGACCCC TACTTTGGGT TTGAAGAAGC AAAGAGGAAG 
TTACAAGAAA GACCCTGGCT CGTGGATTCC TACAGCGAGT GGCTTCAGAG ATTAAAGGGG 
CCCCCTCATA AATGTGCCTT AATTTTCGCA GATAACAGTG GAATAGACAT CATTTTGGGA 
GTCTTCCCCT TTGTCAGGGA GCTACTCCTT AGAGGGACAG AGGTCATCCT GGCGTGCAAC 
TCAGGCCCCG CCCTGAACGA CGTGACCCAC AGCGAGTCCC TCATCGTGGC AGAGCGTATT 
GCGGGCATGG ACCCTGTCGT GCACTCTGCG CTCCAGGAAG AGAGGCTGCT GCTGGTGCAG 
ACGGGCTCCA GCTCCCCGTG CCTCGACCTC AGCCGCCTGG ATAAGGGGCT GGCCGCACTG 
GTGCGGGAGC GTGGCGCGGA TCTGGTGGTC ATCGAGGGCA TGGGCCGTGC TGTCCACACA 
AACTACCACG CAGCCCTGCG CTGCGAGAGC CTCAAGCTGG CCGTCATCAA GAACGCGTGG 
CTGGCCGAGC GGCTGGGCGG CCGGCTCTTC AGCGTCATCT TCAAGTACGA GGTCCCAGCC 
GAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060686.2
CDS	18..2363
Translation	MSWPGTFKMAECGASGSGSSGDSLDKSITLPPDEIFRNLENAKRFAIDIGGSLTKLAYYSTVQHKVAKVRSFDHSGKDTEREHEPPYEISVQEEITARLHFIKFENTYIEACLDFIKDHLVNTETKVIQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKDSDPEFRFQTNHPHIFPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQEFSKEDMAKSLLHMISNDIGQLACLHARLHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKGAEQDNPNQYSWGENYAGSSGLMSASPELGPAQRARSGTFDLLEMDRLERPLVDLPLLLDPPSYVPDTVDLTDDALARKYWLTCFEEALDGVVKRAVASQPDSVDAAERAEKFRQKYWNKLQTLRQQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQRENGVALRCFPGVVRSLDALGWEERQLALVKGLLAGNVFDWGAKAVSAVLESDPYFGFEEAKRKLQERPWLVDSYSEWLQRLKGPPHKCALIFADNSGIDIILGVFPFVRELLLRGTEVILACNSGPALNDVTHSESLIVAERIAGMDPVVHSALQEERLLLVQTGSSSPCLDLSRLDKGLAALVRERGADLVVIEGMGRAVHTNYHAALRCESLKLAVIKNAWLAERLGGRLFSVIFKYEVPAE

Target ORF information:

RefSeq Version	NM_018216.2
Organism	Homo sapiens(human)
Definition	Homo sapiens pantothenate kinase 4 (PANK4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018216.2

ORF Insert Sequence:

ATGAGCTGGC CGGGCACTTT CAAAATGGCG GAGTGTGGAG CGAGCGGCAG CGGGAGCAGC 
GGGGACAGTC TGGACAAGAG CATCACGCTG CCCCCCGACG AGATCTTCCG CAACCTGGAG 
AACGCCAAGC GCTTCGCCAT CGACATAGGC GGGTCGTTAA CCAAGCTGGC CTACTATTCA 
ACGGTACAGC ACAAAGTCGC CAAGGTGCGG TCTTTCGACC ACTCCGGAAA GGACACAGAA 
CGTGAACATG AGCCGCCCTA TGAGATTTCA GTTCAAGAAG AGATCACTGC TCGACTGCAC 
TTCATTAAGT TTGAGAATAC CTACATCGAA GCCTGCCTGG ACTTCATCAA AGACCATCTC 
GTCAACACAG AGACCAAGGT CATCCAGGCG ACCGGGGGCG GGGCCTACAA GTTCAAAGAC 
CTCATCGAAG AGAAGCTGCG GCTGAAAGTC GACAAGGAGG ACGTGATGAC GTGCCTGATT 
AAGGGGTGCA ACTTCGTGCT CAAGAACATC CCCCATGAGG CCTTCGTGTA CCAGAAGGAT 
TCCGACCCTG AGTTCCGGTT CCAGACCAAC CACCCCCACA TTTTCCCCTA TCTTCTTGTC 
AATATCGGCT CTGGAGTCTC CATCGTGAAG GTGGAGACGG AGGACAGGTT CGAGTGGGTC 
GGCGGCAGCT CCATTGGAGG CGGCACCTTC TGGGGGCTTG GCGCTCTGCT CACCAAAACG 
AAGAAGTTTG ACGAGCTCCT GCACCTGGCC TCGAGGGGCC AGCACAGCAA TGTGGACATG 
CTGGTGCGGG ACGTCTACGG CGGCGCCCAC CAGACTCTCG GGCTGAGCGG GAACCTCATC 
GCCAGCAGCT TCGGGAAGTC GGCCACCGCC GACCAAGAGT TCTCCAAAGA AGACATGGCG 
AAGAGCCTGC TGCACATGAT CAGCAACGAC ATTGGGCAGC TGGCCTGCCT CCACGCACGG 
CTGCACAGCC TGGACCGCGT GTACTTTGGA GGCTTCTTTA TCCGGGGCCA CCCCGTGACC 
ATGCGCACCA TCACCTATAG CATCAACTTC TTCTCCAAGG GGGAAGTGCA GGCGCTGTTT 
CTGAGGCACG AAGGCTACCT GGGAGCCATC GGAGCGTTCC TGAAAGGAGC TGAGCAGGAC 
AATCCTAACC AGTACAGCTG GGGAGAGAAC TATGCAGGCA GCTCCGGGCT GATGAGTGCA 
TCACCCGAGC TCGGCCCGGC GCAGCGGGCG CGGAGTGGCA CTTTTGACTT GCTGGAAATG 
GACCGGCTGG AGAGGCCACT GGTTGACCTG CCGCTCCTCC TGGACCCGCC CTCCTACGTG 
CCCGACACGG TGGACCTCAC CGATGACGCT CTGGCCCGAA AATACTGGCT CACCTGCTTT 
GAGGAGGCCC TGGACGGGGT AGTGAAGCGC GCAGTGGCGA GCCAGCCAGA CTCTGTGGAT 
GCAGCCGAGA GGGCGGAGAA GTTCCGGCAG AAGTACTGGA ACAAGCTTCA GACCCTGAGG 
CAGCAGCCCT TCGCCTATGG GACCCTGACC GTGCGCAGCC TGCTGGACAC CAGGGAGCAC 
TGTCTGAACG AGTTCAACTT CCCGGATCCC TACTCCAAAG TGAAGCAGCG GGAGAATGGC 
GTGGCGCTGA GGTGCTTCCC CGGGGTCGTG CGCTCCCTGG ACGCGCTGGG CTGGGAGGAA 
CGGCAGCTGG CGCTGGTGAA AGGCCTCCTG GCGGGGAATG TCTTCGACTG GGGGGCCAAA 
GCCGTGTCTG CTGTCCTTGA ATCCGACCCC TACTTTGGGT TTGAAGAAGC AAAGAGGAAG 
TTACAAGAAA GACCCTGGCT CGTGGATTCC TACAGCGAGT GGCTTCAGAG ATTAAAGGGG 
CCCCCTCATA AATGTGCCTT AATTTTCGCA GATAACAGTG GAATAGACAT CATTTTGGGA 
GTCTTCCCCT TTGTCAGGGA GCTACTCCTT AGAGGGACAG AGGTCATCCT GGCGTGCAAC 
TCAGGCCCCG CCCTGAACGA CGTGACCCAC AGCGAGTCCC TCATCGTGGC AGAGCGTATT 
GCGGGCATGG ACCCTGTCGT GCACTCTGCG CTCCAGGAAG AGAGGCTGCT GCTGGTGCAG 
ACGGGCTCCA GCTCCCCGTG CCTCGACCTC AGCCGCCTGG ATAAGGGGCT GGCCGCACTG 
GTGCGGGAGC GTGGCGCGGA TCTGGTGGTC ATCGAGGGCA TGGGCCGTGC TGTCCACACA 
AACTACCACG CAGCCCTGCG CTGCGAGAGC CTCAAGCTGG CCGTCATCAA GAACGCGTGG 
CTGGCCGAGC GGCTGGGCGG CCGGCTCTTC AGCGTCATCT TCAAGTACGA GGTCCCAGCC 
GAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PANK4 ( XM_011541708.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011540010.2 Homo sapiens pantothenate kinase 4 (PANK4), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu90181
Clone ID Related Accession (Same CDS sequence)	XM_011541708.2 , XM_011541708.3
Accession Version	XM_011541708.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1230bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	pantothenate kinase 4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011541708.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGAGT GTGGAGCGAG CGGCAGCGGG AGCAGCGGGG ACAGTCTGGA CAAGAGCATC 
ACGCTGCCCC CCGACGAGAT CTTCCGCAAC CTGGAGAACG CCAAGCGCTT CGCCATCGAC 
ATAGGCGGGT CGTTAACCAA GCTGGCCTAC TATTCAACGG TACAGCACAA AGTCGCCAAG 
GTGCGGTCTT TCGACCACTC CGGAAAGGAC ACAGAACGTG AACATGAGCC GCCCTATGAG 
ATTTCAGTTC AAGAAGAGAT CACTGCTCGA CTGCACTTCA TTAAGTTTGA GAATACCTAC 
ATCGAAGCCT GCCTGGACTT CATCAAAGAC CATCTCGTCA ACACAGAGAC CAAGGTCATC 
CAGGCGACCG GGGGCGGGGC CTACAAGTTC AAAGACCTCA TCGAAGAGAA GCTGCGGCTG 
AAAGTCGACA AGGAGGACGT GATGACGTGC CTGATTAAGG GGTGCAACTT CGTGCTCAAG 
AACATCCCCC ATGAGGCCTT CGTGTACCAG AAGGATTCCG ACCCTGAGTT CCGGTTCCAG 
ACCAACCACC CCCACATTTT CCCCTATCTT CTTGTCAATA TCGGCTCTGG AGTCTCCATC 
GTGAAGGTGG AGACGGAGGA CAGGTTCGAG TGGGTCGGCG GCAGCTCCAT TGGAGGCGGC 
ACCTTCTGGG GGCTTGGCGC TCTGCTCACC AAAACGAAGA AGTTTGACGA GCTCCTGCAC 
CTGGCCTCGA GGGGCCAGCA CAGCAATGTG GACATGCTGG TGCGGGACGT CTACGGCGGC 
GCCCACCAGA CTCTCGGGCT GAGCGGGAAC CTCATCGCCA GCAGCTTCGG GAAGTCGGCC 
ACCGCCGACC AAGAGTTCTC CAAAGAAGAC ATGGCGAAGA GCCTGCTGCA CATGATCAGC 
AACGACATTG GGCAGCTGGC CTGCCTCCAC GCACGGCTGC ACAGCCTGGA CCGCGTGTAC 
TTTGGAGGCT TCTTTATCCG GGGCCACCCC GTGACCATGC GCACCATCAC CTATAGCATC 
AACTTCTTCT CCAAGGGGGA AGTGCAGGCG CTGTTTCTGA GGCACGAAGG CTACCTGGGA 
GCCATCGGAG CGTTCCTGAA AGGAGCTGAG CAGGACAATC CTAACCAGTA CAGCTGGGGA 
GAGAACTATG CAGGCAGCTC CGGGCTGATG AGTGCATCAC CCGAGCTCGG CCCGGCGCAG 
CGGGCGCGGA GTGGCACTAG AGATTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011540010.2
CDS	8..1237
Translation	MAECGASGSGSSGDSLDKSITLPPDEIFRNLENAKRFAIDIGGSLTKLAYYSTVQHKVAKVRSFDHSGKDTEREHEPPYEISVQEEITARLHFIKFENTYIEACLDFIKDHLVNTETKVIQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKDSDPEFRFQTNHPHIFPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQEFSKEDMAKSLLHMISNDIGQLACLHARLHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKGAEQDNPNQYSWGENYAGSSGLMSASPELGPAQRARSGTRDC

Target ORF information:

RefSeq Version	XM_011541708.2
Organism	Homo sapiens(human)
Definition	Homo sapiens pantothenate kinase 4 (PANK4), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011541708.2

ORF Insert Sequence:

ATGGCGGAGT GTGGAGCGAG CGGCAGCGGG AGCAGCGGGG ACAGTCTGGA CAAGAGCATC 
ACGCTGCCCC CCGACGAGAT CTTCCGCAAC CTGGAGAACG CCAAGCGCTT CGCCATCGAC 
ATAGGCGGGT CGTTAACCAA GCTGGCCTAC TATTCAACGG TACAGCACAA AGTCGCCAAG 
GTGCGGTCTT TCGACCACTC CGGAAAGGAC ACAGAACGTG AACATGAGCC GCCCTATGAG 
ATTTCAGTTC AAGAAGAGAT CACTGCTCGA CTGCACTTCA TTAAGTTTGA GAATACCTAC 
ATCGAAGCCT GCCTGGACTT CATCAAAGAC CATCTCGTCA ACACAGAGAC CAAGGTCATC 
CAGGCGACCG GGGGCGGGGC CTACAAGTTC AAAGACCTCA TCGAAGAGAA GCTGCGGCTG 
AAAGTCGACA AGGAGGACGT GATGACGTGC CTGATTAAGG GGTGCAACTT CGTGCTCAAG 
AACATCCCCC ATGAGGCCTT CGTGTACCAG AAGGATTCCG ACCCTGAGTT CCGGTTCCAG 
ACCAACCACC CCCACATTTT CCCCTATCTT CTTGTCAATA TCGGCTCTGG AGTCTCCATC 
GTGAAGGTGG AGACGGAGGA CAGGTTCGAG TGGGTCGGCG GCAGCTCCAT TGGAGGCGGC 
ACCTTCTGGG GGCTTGGCGC TCTGCTCACC AAAACGAAGA AGTTTGACGA GCTCCTGCAC 
CTGGCCTCGA GGGGCCAGCA CAGCAATGTG GACATGCTGG TGCGGGACGT CTACGGCGGC 
GCCCACCAGA CTCTCGGGCT GAGCGGGAAC CTCATCGCCA GCAGCTTCGG GAAGTCGGCC 
ACCGCCGACC AAGAGTTCTC CAAAGAAGAC ATGGCGAAGA GCCTGCTGCA CATGATCAGC 
AACGACATTG GGCAGCTGGC CTGCCTCCAC GCACGGCTGC ACAGCCTGGA CCGCGTGTAC 
TTTGGAGGCT TCTTTATCCG GGGCCACCCC GTGACCATGC GCACCATCAC CTATAGCATC 
AACTTCTTCT CCAAGGGGGA AGTGCAGGCG CTGTTTCTGA GGCACGAAGG CTACCTGGGA 
GCCATCGGAG CGTTCCTGAA AGGAGCTGAG CAGGACAATC CTAACCAGTA CAGCTGGGGA 
GAGAACTATG CAGGCAGCTC CGGGCTGATG AGTGCATCAC CCGAGCTCGG CCCGGCGCAG 
CGGGCGCGGA GTGGCACTAG AGATTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PANK4 ( XM_011541708.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011540010.2 Homo sapiens pantothenate kinase 4 (inactive) (PANK4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu90181
Clone ID Related Accession (Same CDS sequence)	XM_011541708.2 , XM_011541708.3
Accession Version	XM_011541708.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1230bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	4'-phosphopantetheine phosphatase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011541708.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGAGT GTGGAGCGAG CGGCAGCGGG AGCAGCGGGG ACAGTCTGGA CAAGAGCATC 
ACGCTGCCCC CCGACGAGAT CTTCCGCAAC CTGGAGAACG CCAAGCGCTT CGCCATCGAC 
ATAGGCGGGT CGTTAACCAA GCTGGCCTAC TATTCAACGG TACAGCACAA AGTCGCCAAG 
GTGCGGTCTT TCGACCACTC CGGAAAGGAC ACAGAACGTG AACATGAGCC GCCCTATGAG 
ATTTCAGTTC AAGAAGAGAT CACTGCTCGA CTGCACTTCA TTAAGTTTGA GAATACCTAC 
ATCGAAGCCT GCCTGGACTT CATCAAAGAC CATCTCGTCA ACACAGAGAC CAAGGTCATC 
CAGGCGACCG GGGGCGGGGC CTACAAGTTC AAAGACCTCA TCGAAGAGAA GCTGCGGCTG 
AAAGTCGACA AGGAGGACGT GATGACGTGC CTGATTAAGG GGTGCAACTT CGTGCTCAAG 
AACATCCCCC ATGAGGCCTT CGTGTACCAG AAGGATTCCG ACCCTGAGTT CCGGTTCCAG 
ACCAACCACC CCCACATTTT CCCCTATCTT CTTGTCAATA TCGGCTCTGG AGTCTCCATC 
GTGAAGGTGG AGACGGAGGA CAGGTTCGAG TGGGTCGGCG GCAGCTCCAT TGGAGGCGGC 
ACCTTCTGGG GGCTTGGCGC TCTGCTCACC AAAACGAAGA AGTTTGACGA GCTCCTGCAC 
CTGGCCTCGA GGGGCCAGCA CAGCAATGTG GACATGCTGG TGCGGGACGT CTACGGCGGC 
GCCCACCAGA CTCTCGGGCT GAGCGGGAAC CTCATCGCCA GCAGCTTCGG GAAGTCGGCC 
ACCGCCGACC AAGAGTTCTC CAAAGAAGAC ATGGCGAAGA GCCTGCTGCA CATGATCAGC 
AACGACATTG GGCAGCTGGC CTGCCTCCAC GCACGGCTGC ACAGCCTGGA CCGCGTGTAC 
TTTGGAGGCT TCTTTATCCG GGGCCACCCC GTGACCATGC GCACCATCAC CTATAGCATC 
AACTTCTTCT CCAAGGGGGA AGTGCAGGCG CTGTTTCTGA GGCACGAAGG CTACCTGGGA 
GCCATCGGAG CGTTCCTGAA AGGAGCTGAG CAGGACAATC CTAACCAGTA CAGCTGGGGA 
GAGAACTATG CAGGCAGCTC CGGGCTGATG AGTGCATCAC CCGAGCTCGG CCCGGCGCAG 
CGGGCGCGGA GTGGCACTAG AGATTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011540010.2
CDS	11..1240
Translation	MAECGASGSGSSGDSLDKSITLPPDEIFRNLENAKRFAIDIGGSLTKLAYYSTVQHKVAKVRSFDHSGKDTEREHEPPYEISVQEEITARLHFIKFENTYIEACLDFIKDHLVNTETKVIQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKDSDPEFRFQTNHPHIFPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQEFSKEDMAKSLLHMISNDIGQLACLHARLHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKGAEQDNPNQYSWGENYAGSSGLMSASPELGPAQRARSGTRDC

Target ORF information:

RefSeq Version	XM_011541708.3
Organism	Homo sapiens(human)
Definition	Homo sapiens pantothenate kinase 4 (inactive) (PANK4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011541708.3

ORF Insert Sequence:

ATGGCGGAGT GTGGAGCGAG CGGCAGCGGG AGCAGCGGGG ACAGTCTGGA CAAGAGCATC 
ACGCTGCCCC CCGACGAGAT CTTCCGCAAC CTGGAGAACG CCAAGCGCTT CGCCATCGAC 
ATAGGCGGGT CGTTAACCAA GCTGGCCTAC TATTCAACGG TACAGCACAA AGTCGCCAAG 
GTGCGGTCTT TCGACCACTC CGGAAAGGAC ACAGAACGTG AACATGAGCC GCCCTATGAG 
ATTTCAGTTC AAGAAGAGAT CACTGCTCGA CTGCACTTCA TTAAGTTTGA GAATACCTAC 
ATCGAAGCCT GCCTGGACTT CATCAAAGAC CATCTCGTCA ACACAGAGAC CAAGGTCATC 
CAGGCGACCG GGGGCGGGGC CTACAAGTTC AAAGACCTCA TCGAAGAGAA GCTGCGGCTG 
AAAGTCGACA AGGAGGACGT GATGACGTGC CTGATTAAGG GGTGCAACTT CGTGCTCAAG 
AACATCCCCC ATGAGGCCTT CGTGTACCAG AAGGATTCCG ACCCTGAGTT CCGGTTCCAG 
ACCAACCACC CCCACATTTT CCCCTATCTT CTTGTCAATA TCGGCTCTGG AGTCTCCATC 
GTGAAGGTGG AGACGGAGGA CAGGTTCGAG TGGGTCGGCG GCAGCTCCAT TGGAGGCGGC 
ACCTTCTGGG GGCTTGGCGC TCTGCTCACC AAAACGAAGA AGTTTGACGA GCTCCTGCAC 
CTGGCCTCGA GGGGCCAGCA CAGCAATGTG GACATGCTGG TGCGGGACGT CTACGGCGGC 
GCCCACCAGA CTCTCGGGCT GAGCGGGAAC CTCATCGCCA GCAGCTTCGG GAAGTCGGCC 
ACCGCCGACC AAGAGTTCTC CAAAGAAGAC ATGGCGAAGA GCCTGCTGCA CATGATCAGC 
AACGACATTG GGCAGCTGGC CTGCCTCCAC GCACGGCTGC ACAGCCTGGA CCGCGTGTAC 
TTTGGAGGCT TCTTTATCCG GGGCCACCCC GTGACCATGC GCACCATCAC CTATAGCATC 
AACTTCTTCT CCAAGGGGGA AGTGCAGGCG CTGTTTCTGA GGCACGAAGG CTACCTGGGA 
GCCATCGGAG CGTTCCTGAA AGGAGCTGAG CAGGACAATC CTAACCAGTA CAGCTGGGGA 
GAGAACTATG CAGGCAGCTC CGGGCTGATG AGTGCATCAC CCGAGCTCGG CCCGGCGCAG 
CGGGCGCGGA GTGGCACTAG AGATTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PANK4 ( NM_018216.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_060686.3 Homo sapiens pantothenate kinase 4 (inactive) (PANK4), mRNA.

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CloneID	OHu107068
Clone ID Related Accession (Same CDS sequence)	NM_018216.4 , NM_018216.3
Accession Version	NM_018216.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2322bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Homo sapiens(human)
Product	4'-phosphopantetheine phosphatase
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC316156.1 and AK001644.1. On May 17, 2019 this sequence version replaced NM_018216.3. CCDS Note: The coding region has been updated to shorten the N-terminus to one that is more supported by conservation. ##Evidence-Data-START## Transcript exon combination :: BC043496.1, BK000012.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000378466.9/ ENSP00000367727.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGAGT GTGGAGCGAG CGGCAGCGGG AGCAGCGGGG ACAGTCTGGA CAAGAGCATC 
ACGCTGCCCC CCGACGAGAT CTTCCGCAAC CTGGAGAACG CCAAGCGCTT CGCCATCGAC 
ATAGGCGGGT CGTTAACCAA GCTGGCCTAC TATTCAACGG TACAGCACAA AGTCGCCAAG 
GTGCGGTCTT TCGACCACTC CGGAAAGGAC ACAGAACGTG AACATGAGCC GCCCTATGAG 
ATTTCAGTTC AAGAAGAGAT CACTGCTCGA CTGCACTTCA TTAAGTTTGA GAATACCTAC 
ATCGAAGCCT GCCTGGACTT CATCAAAGAC CATCTCGTCA ACACAGAGAC CAAGGTCATC 
CAGGCGACCG GGGGCGGGGC CTACAAGTTC AAAGACCTCA TCGAAGAGAA GCTGCGGCTG 
AAAGTCGACA AGGAGGACGT GATGACGTGC CTGATTAAGG GGTGCAACTT CGTGCTCAAG 
AACATCCCCC ATGAGGCCTT CGTGTACCAG AAGGATTCCG ACCCTGAGTT CCGGTTCCAG 
ACCAACCACC CCCACATTTT CCCCTATCTT CTTGTCAATA TCGGCTCTGG AGTCTCCATC 
GTGAAGGTGG AGACGGAGGA CAGGTTCGAG TGGGTCGGCG GCAGCTCCAT TGGAGGCGGC 
ACCTTCTGGG GGCTTGGCGC TCTGCTCACC AAAACGAAGA AGTTTGACGA GCTCCTGCAC 
CTGGCCTCGA GGGGCCAGCA CAGCAATGTG GACATGCTGG TGCGGGACGT CTACGGCGGC 
GCCCACCAGA CTCTCGGGCT GAGCGGGAAC CTCATCGCCA GCAGCTTCGG GAAGTCGGCC 
ACCGCCGACC AAGAGTTCTC CAAAGAAGAC ATGGCGAAGA GCCTGCTGCA CATGATCAGC 
AACGACATTG GGCAGCTGGC CTGCCTCCAC GCACGGCTGC ACAGCCTGGA CCGCGTGTAC 
TTTGGAGGCT TCTTTATCCG GGGCCACCCC GTGACCATGC GCACCATCAC CTATAGCATC 
AACTTCTTCT CCAAGGGGGA AGTGCAGGCG CTGTTTCTGA GGCACGAAGG CTACCTGGGA 
GCCATCGGAG CGTTCCTGAA AGGAGCTGAG CAGGACAATC CTAACCAGTA CAGCTGGGGA 
GAGAACTATG CAGGCAGCTC CGGGCTGATG AGTGCATCAC CCGAGCTCGG CCCGGCGCAG 
CGGGCGCGGA GTGGCACTTT TGACTTGCTG GAAATGGACC GGCTGGAGAG GCCACTGGTT 
GACCTGCCGC TCCTCCTGGA CCCGCCCTCC TACGTGCCCG ACACGGTGGA CCTCACCGAT 
GACGCTCTGG CCCGAAAATA CTGGCTCACC TGCTTTGAGG AGGCCCTGGA CGGGGTAGTG 
AAGCGCGCAG TGGCGAGCCA GCCAGACTCT GTGGATGCAG CCGAGAGGGC GGAGAAGTTC 
CGGCAGAAGT ACTGGAACAA GCTTCAGACC CTGAGGCAGC AGCCCTTCGC CTATGGGACC 
CTGACCGTGC GCAGCCTGCT GGACACCAGG GAGCACTGTC TGAACGAGTT CAACTTCCCG 
GATCCCTACT CCAAAGTGAA GCAGCGGGAG AATGGCGTGG CGCTGAGGTG CTTCCCCGGG 
GTCGTGCGCT CCCTGGACGC GCTGGGCTGG GAGGAACGGC AGCTGGCGCT GGTGAAAGGC 
CTCCTGGCGG GGAATGTCTT CGACTGGGGG GCCAAAGCCG TGTCTGCTGT CCTTGAATCC 
GACCCCTACT TTGGGTTTGA AGAAGCAAAG AGGAAGTTAC AAGAAAGACC CTGGCTCGTG 
GATTCCTACA GCGAGTGGCT TCAGAGATTA AAGGGGCCCC CTCATAAATG TGCCTTAATT 
TTCGCAGATA ACAGTGGAAT AGACATCATT TTGGGAGTCT TCCCCTTTGT CAGGGAGCTA 
CTCCTTAGAG GGACAGAGGT CATCCTGGCG TGCAACTCAG GCCCCGCCCT GAACGACGTG 
ACCCACAGCG AGTCCCTCAT CGTGGCAGAG CGTATTGCGG GCATGGACCC TGTCGTGCAC 
TCTGCGCTCC AGGAAGAGAG GCTGCTGCTG GTGCAGACGG GCTCCAGCTC CCCGTGCCTC 
GACCTCAGCC GCCTGGATAA GGGGCTGGCC GCACTGGTGC GGGAGCGTGG CGCGGATCTG 
GTGGTCATCG AGGGCATGGG CCGTGCTGTC CACACAAACT ACCACGCAGC CCTGCGCTGC 
GAGAGCCTCA AGCTGGCCGT CATCAAGAAC GCGTGGCTGG CCGAGCGGCT GGGCGGCCGG 
CTCTTCAGCG TCATCTTCAA GTACGAGGTC CCAGCCGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060686.3
CDS	10..2331
Translation	MAECGASGSGSSGDSLDKSITLPPDEIFRNLENAKRFAIDIGGSLTKLAYYSTVQHKVAKVRSFDHSGKDTEREHEPPYEISVQEEITARLHFIKFENTYIEACLDFIKDHLVNTETKVIQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKDSDPEFRFQTNHPHIFPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQEFSKEDMAKSLLHMISNDIGQLACLHARLHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKGAEQDNPNQYSWGENYAGSSGLMSASPELGPAQRARSGTFDLLEMDRLERPLVDLPLLLDPPSYVPDTVDLTDDALARKYWLTCFEEALDGVVKRAVASQPDSVDAAERAEKFRQKYWNKLQTLRQQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQRENGVALRCFPGVVRSLDALGWEERQLALVKGLLAGNVFDWGAKAVSAVLESDPYFGFEEAKRKLQERPWLVDSYSEWLQRLKGPPHKCALIFADNSGIDIILGVFPFVRELLLRGTEVILACNSGPALNDVTHSESLIVAERIAGMDPVVHSALQEERLLLVQTGSSSPCLDLSRLDKGLAALVRERGADLVVIEGMGRAVHTNYHAALRCESLKLAVIKNAWLAERLGGRLFSVIFKYEVPAE

Target ORF information:

RefSeq Version	NM_018216.4
Organism	Homo sapiens(human)
Definition	Homo sapiens pantothenate kinase 4 (inactive) (PANK4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018216.4

ORF Insert Sequence:

ATGGCGGAGT GTGGAGCGAG CGGCAGCGGG AGCAGCGGGG ACAGTCTGGA CAAGAGCATC 
ACGCTGCCCC CCGACGAGAT CTTCCGCAAC CTGGAGAACG CCAAGCGCTT CGCCATCGAC 
ATAGGCGGGT CGTTAACCAA GCTGGCCTAC TATTCAACGG TACAGCACAA AGTCGCCAAG 
GTGCGGTCTT TCGACCACTC CGGAAAGGAC ACAGAACGTG AACATGAGCC GCCCTATGAG 
ATTTCAGTTC AAGAAGAGAT CACTGCTCGA CTGCACTTCA TTAAGTTTGA GAATACCTAC 
ATCGAAGCCT GCCTGGACTT CATCAAAGAC CATCTCGTCA ACACAGAGAC CAAGGTCATC 
CAGGCGACCG GGGGCGGGGC CTACAAGTTC AAAGACCTCA TCGAAGAGAA GCTGCGGCTG 
AAAGTCGACA AGGAGGACGT GATGACGTGC CTGATTAAGG GGTGCAACTT CGTGCTCAAG 
AACATCCCCC ATGAGGCCTT CGTGTACCAG AAGGATTCCG ACCCTGAGTT CCGGTTCCAG 
ACCAACCACC CCCACATTTT CCCCTATCTT CTTGTCAATA TCGGCTCTGG AGTCTCCATC 
GTGAAGGTGG AGACGGAGGA CAGGTTCGAG TGGGTCGGCG GCAGCTCCAT TGGAGGCGGC 
ACCTTCTGGG GGCTTGGCGC TCTGCTCACC AAAACGAAGA AGTTTGACGA GCTCCTGCAC 
CTGGCCTCGA GGGGCCAGCA CAGCAATGTG GACATGCTGG TGCGGGACGT CTACGGCGGC 
GCCCACCAGA CTCTCGGGCT GAGCGGGAAC CTCATCGCCA GCAGCTTCGG GAAGTCGGCC 
ACCGCCGACC AAGAGTTCTC CAAAGAAGAC ATGGCGAAGA GCCTGCTGCA CATGATCAGC 
AACGACATTG GGCAGCTGGC CTGCCTCCAC GCACGGCTGC ACAGCCTGGA CCGCGTGTAC 
TTTGGAGGCT TCTTTATCCG GGGCCACCCC GTGACCATGC GCACCATCAC CTATAGCATC 
AACTTCTTCT CCAAGGGGGA AGTGCAGGCG CTGTTTCTGA GGCACGAAGG CTACCTGGGA 
GCCATCGGAG CGTTCCTGAA AGGAGCTGAG CAGGACAATC CTAACCAGTA CAGCTGGGGA 
GAGAACTATG CAGGCAGCTC CGGGCTGATG AGTGCATCAC CCGAGCTCGG CCCGGCGCAG 
CGGGCGCGGA GTGGCACTTT TGACTTGCTG GAAATGGACC GGCTGGAGAG GCCACTGGTT 
GACCTGCCGC TCCTCCTGGA CCCGCCCTCC TACGTGCCCG ACACGGTGGA CCTCACCGAT 
GACGCTCTGG CCCGAAAATA CTGGCTCACC TGCTTTGAGG AGGCCCTGGA CGGGGTAGTG 
AAGCGCGCAG TGGCGAGCCA GCCAGACTCT GTGGATGCAG CCGAGAGGGC GGAGAAGTTC 
CGGCAGAAGT ACTGGAACAA GCTTCAGACC CTGAGGCAGC AGCCCTTCGC CTATGGGACC 
CTGACCGTGC GCAGCCTGCT GGACACCAGG GAGCACTGTC TGAACGAGTT CAACTTCCCG 
GATCCCTACT CCAAAGTGAA GCAGCGGGAG AATGGCGTGG CGCTGAGGTG CTTCCCCGGG 
GTCGTGCGCT CCCTGGACGC GCTGGGCTGG GAGGAACGGC AGCTGGCGCT GGTGAAAGGC 
CTCCTGGCGG GGAATGTCTT CGACTGGGGG GCCAAAGCCG TGTCTGCTGT CCTTGAATCC 
GACCCCTACT TTGGGTTTGA AGAAGCAAAG AGGAAGTTAC AAGAAAGACC CTGGCTCGTG 
GATTCCTACA GCGAGTGGCT TCAGAGATTA AAGGGGCCCC CTCATAAATG TGCCTTAATT 
TTCGCAGATA ACAGTGGAAT AGACATCATT TTGGGAGTCT TCCCCTTTGT CAGGGAGCTA 
CTCCTTAGAG GGACAGAGGT CATCCTGGCG TGCAACTCAG GCCCCGCCCT GAACGACGTG 
ACCCACAGCG AGTCCCTCAT CGTGGCAGAG CGTATTGCGG GCATGGACCC TGTCGTGCAC 
TCTGCGCTCC AGGAAGAGAG GCTGCTGCTG GTGCAGACGG GCTCCAGCTC CCCGTGCCTC 
GACCTCAGCC GCCTGGATAA GGGGCTGGCC GCACTGGTGC GGGAGCGTGG CGCGGATCTG 
GTGGTCATCG AGGGCATGGG CCGTGCTGTC CACACAAACT ACCACGCAGC CCTGCGCTGC 
GAGAGCCTCA AGCTGGCCGT CATCAAGAAC GCGTGGCTGG CCGAGCGGCT GGGCGGCCGG 
CTCTTCAGCG TCATCTTCAA GTACGAGGTC CCAGCCGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PANK4 ( NM_018216.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_060686.3 Homo sapiens pantothenate kinase 4 (PANK4), mRNA.

Price & Availability↑

CloneID	OHu107068
Clone ID Related Accession (Same CDS sequence)	NM_018216.4 , NM_018216.3
Accession Version	NM_018216.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2322bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-26
Organism	Homo sapiens(human)
Product	pantothenate kinase 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC316156.1, AK001644.1 and AI301430.1. On Jul 14, 2018 this sequence version replaced NM_018216.2. CCDS Note: The coding region has been updated to shorten the N-terminus to one that is more supported by conservation. ##Evidence-Data-START## Transcript exon combination :: AK001644.1, BC043496.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGAGT GTGGAGCGAG CGGCAGCGGG AGCAGCGGGG ACAGTCTGGA CAAGAGCATC 
ACGCTGCCCC CCGACGAGAT CTTCCGCAAC CTGGAGAACG CCAAGCGCTT CGCCATCGAC 
ATAGGCGGGT CGTTAACCAA GCTGGCCTAC TATTCAACGG TACAGCACAA AGTCGCCAAG 
GTGCGGTCTT TCGACCACTC CGGAAAGGAC ACAGAACGTG AACATGAGCC GCCCTATGAG 
ATTTCAGTTC AAGAAGAGAT CACTGCTCGA CTGCACTTCA TTAAGTTTGA GAATACCTAC 
ATCGAAGCCT GCCTGGACTT CATCAAAGAC CATCTCGTCA ACACAGAGAC CAAGGTCATC 
CAGGCGACCG GGGGCGGGGC CTACAAGTTC AAAGACCTCA TCGAAGAGAA GCTGCGGCTG 
AAAGTCGACA AGGAGGACGT GATGACGTGC CTGATTAAGG GGTGCAACTT CGTGCTCAAG 
AACATCCCCC ATGAGGCCTT CGTGTACCAG AAGGATTCCG ACCCTGAGTT CCGGTTCCAG 
ACCAACCACC CCCACATTTT CCCCTATCTT CTTGTCAATA TCGGCTCTGG AGTCTCCATC 
GTGAAGGTGG AGACGGAGGA CAGGTTCGAG TGGGTCGGCG GCAGCTCCAT TGGAGGCGGC 
ACCTTCTGGG GGCTTGGCGC TCTGCTCACC AAAACGAAGA AGTTTGACGA GCTCCTGCAC 
CTGGCCTCGA GGGGCCAGCA CAGCAATGTG GACATGCTGG TGCGGGACGT CTACGGCGGC 
GCCCACCAGA CTCTCGGGCT GAGCGGGAAC CTCATCGCCA GCAGCTTCGG GAAGTCGGCC 
ACCGCCGACC AAGAGTTCTC CAAAGAAGAC ATGGCGAAGA GCCTGCTGCA CATGATCAGC 
AACGACATTG GGCAGCTGGC CTGCCTCCAC GCACGGCTGC ACAGCCTGGA CCGCGTGTAC 
TTTGGAGGCT TCTTTATCCG GGGCCACCCC GTGACCATGC GCACCATCAC CTATAGCATC 
AACTTCTTCT CCAAGGGGGA AGTGCAGGCG CTGTTTCTGA GGCACGAAGG CTACCTGGGA 
GCCATCGGAG CGTTCCTGAA AGGAGCTGAG CAGGACAATC CTAACCAGTA CAGCTGGGGA 
GAGAACTATG CAGGCAGCTC CGGGCTGATG AGTGCATCAC CCGAGCTCGG CCCGGCGCAG 
CGGGCGCGGA GTGGCACTTT TGACTTGCTG GAAATGGACC GGCTGGAGAG GCCACTGGTT 
GACCTGCCGC TCCTCCTGGA CCCGCCCTCC TACGTGCCCG ACACGGTGGA CCTCACCGAT 
GACGCTCTGG CCCGAAAATA CTGGCTCACC TGCTTTGAGG AGGCCCTGGA CGGGGTAGTG 
AAGCGCGCAG TGGCGAGCCA GCCAGACTCT GTGGATGCAG CCGAGAGGGC GGAGAAGTTC 
CGGCAGAAGT ACTGGAACAA GCTTCAGACC CTGAGGCAGC AGCCCTTCGC CTATGGGACC 
CTGACCGTGC GCAGCCTGCT GGACACCAGG GAGCACTGTC TGAACGAGTT CAACTTCCCG 
GATCCCTACT CCAAAGTGAA GCAGCGGGAG AATGGCGTGG CGCTGAGGTG CTTCCCCGGG 
GTCGTGCGCT CCCTGGACGC GCTGGGCTGG GAGGAACGGC AGCTGGCGCT GGTGAAAGGC 
CTCCTGGCGG GGAATGTCTT CGACTGGGGG GCCAAAGCCG TGTCTGCTGT CCTTGAATCC 
GACCCCTACT TTGGGTTTGA AGAAGCAAAG AGGAAGTTAC AAGAAAGACC CTGGCTCGTG 
GATTCCTACA GCGAGTGGCT TCAGAGATTA AAGGGGCCCC CTCATAAATG TGCCTTAATT 
TTCGCAGATA ACAGTGGAAT AGACATCATT TTGGGAGTCT TCCCCTTTGT CAGGGAGCTA 
CTCCTTAGAG GGACAGAGGT CATCCTGGCG TGCAACTCAG GCCCCGCCCT GAACGACGTG 
ACCCACAGCG AGTCCCTCAT CGTGGCAGAG CGTATTGCGG GCATGGACCC TGTCGTGCAC 
TCTGCGCTCC AGGAAGAGAG GCTGCTGCTG GTGCAGACGG GCTCCAGCTC CCCGTGCCTC 
GACCTCAGCC GCCTGGATAA GGGGCTGGCC GCACTGGTGC GGGAGCGTGG CGCGGATCTG 
GTGGTCATCG AGGGCATGGG CCGTGCTGTC CACACAAACT ACCACGCAGC CCTGCGCTGC 
GAGAGCCTCA AGCTGGCCGT CATCAAGAAC GCGTGGCTGG CCGAGCGGCT GGGCGGCCGG 
CTCTTCAGCG TCATCTTCAA GTACGAGGTC CCAGCCGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060686.3
CDS	10..2331
Translation	MAECGASGSGSSGDSLDKSITLPPDEIFRNLENAKRFAIDIGGSLTKLAYYSTVQHKVAKVRSFDHSGKDTEREHEPPYEISVQEEITARLHFIKFENTYIEACLDFIKDHLVNTETKVIQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKDSDPEFRFQTNHPHIFPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQEFSKEDMAKSLLHMISNDIGQLACLHARLHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKGAEQDNPNQYSWGENYAGSSGLMSASPELGPAQRARSGTFDLLEMDRLERPLVDLPLLLDPPSYVPDTVDLTDDALARKYWLTCFEEALDGVVKRAVASQPDSVDAAERAEKFRQKYWNKLQTLRQQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQRENGVALRCFPGVVRSLDALGWEERQLALVKGLLAGNVFDWGAKAVSAVLESDPYFGFEEAKRKLQERPWLVDSYSEWLQRLKGPPHKCALIFADNSGIDIILGVFPFVRELLLRGTEVILACNSGPALNDVTHSESLIVAERIAGMDPVVHSALQEERLLLVQTGSSSPCLDLSRLDKGLAALVRERGADLVVIEGMGRAVHTNYHAALRCESLKLAVIKNAWLAERLGGRLFSVIFKYEVPAE

Target ORF information:

RefSeq Version	NM_018216.3
Organism	Homo sapiens(human)
Definition	Homo sapiens pantothenate kinase 4 (PANK4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018216.3

ORF Insert Sequence:

ATGGCGGAGT GTGGAGCGAG CGGCAGCGGG AGCAGCGGGG ACAGTCTGGA CAAGAGCATC 
ACGCTGCCCC CCGACGAGAT CTTCCGCAAC CTGGAGAACG CCAAGCGCTT CGCCATCGAC 
ATAGGCGGGT CGTTAACCAA GCTGGCCTAC TATTCAACGG TACAGCACAA AGTCGCCAAG 
GTGCGGTCTT TCGACCACTC CGGAAAGGAC ACAGAACGTG AACATGAGCC GCCCTATGAG 
ATTTCAGTTC AAGAAGAGAT CACTGCTCGA CTGCACTTCA TTAAGTTTGA GAATACCTAC 
ATCGAAGCCT GCCTGGACTT CATCAAAGAC CATCTCGTCA ACACAGAGAC CAAGGTCATC 
CAGGCGACCG GGGGCGGGGC CTACAAGTTC AAAGACCTCA TCGAAGAGAA GCTGCGGCTG 
AAAGTCGACA AGGAGGACGT GATGACGTGC CTGATTAAGG GGTGCAACTT CGTGCTCAAG 
AACATCCCCC ATGAGGCCTT CGTGTACCAG AAGGATTCCG ACCCTGAGTT CCGGTTCCAG 
ACCAACCACC CCCACATTTT CCCCTATCTT CTTGTCAATA TCGGCTCTGG AGTCTCCATC 
GTGAAGGTGG AGACGGAGGA CAGGTTCGAG TGGGTCGGCG GCAGCTCCAT TGGAGGCGGC 
ACCTTCTGGG GGCTTGGCGC TCTGCTCACC AAAACGAAGA AGTTTGACGA GCTCCTGCAC 
CTGGCCTCGA GGGGCCAGCA CAGCAATGTG GACATGCTGG TGCGGGACGT CTACGGCGGC 
GCCCACCAGA CTCTCGGGCT GAGCGGGAAC CTCATCGCCA GCAGCTTCGG GAAGTCGGCC 
ACCGCCGACC AAGAGTTCTC CAAAGAAGAC ATGGCGAAGA GCCTGCTGCA CATGATCAGC 
AACGACATTG GGCAGCTGGC CTGCCTCCAC GCACGGCTGC ACAGCCTGGA CCGCGTGTAC 
TTTGGAGGCT TCTTTATCCG GGGCCACCCC GTGACCATGC GCACCATCAC CTATAGCATC 
AACTTCTTCT CCAAGGGGGA AGTGCAGGCG CTGTTTCTGA GGCACGAAGG CTACCTGGGA 
GCCATCGGAG CGTTCCTGAA AGGAGCTGAG CAGGACAATC CTAACCAGTA CAGCTGGGGA 
GAGAACTATG CAGGCAGCTC CGGGCTGATG AGTGCATCAC CCGAGCTCGG CCCGGCGCAG 
CGGGCGCGGA GTGGCACTTT TGACTTGCTG GAAATGGACC GGCTGGAGAG GCCACTGGTT 
GACCTGCCGC TCCTCCTGGA CCCGCCCTCC TACGTGCCCG ACACGGTGGA CCTCACCGAT 
GACGCTCTGG CCCGAAAATA CTGGCTCACC TGCTTTGAGG AGGCCCTGGA CGGGGTAGTG 
AAGCGCGCAG TGGCGAGCCA GCCAGACTCT GTGGATGCAG CCGAGAGGGC GGAGAAGTTC 
CGGCAGAAGT ACTGGAACAA GCTTCAGACC CTGAGGCAGC AGCCCTTCGC CTATGGGACC 
CTGACCGTGC GCAGCCTGCT GGACACCAGG GAGCACTGTC TGAACGAGTT CAACTTCCCG 
GATCCCTACT CCAAAGTGAA GCAGCGGGAG AATGGCGTGG CGCTGAGGTG CTTCCCCGGG 
GTCGTGCGCT CCCTGGACGC GCTGGGCTGG GAGGAACGGC AGCTGGCGCT GGTGAAAGGC 
CTCCTGGCGG GGAATGTCTT CGACTGGGGG GCCAAAGCCG TGTCTGCTGT CCTTGAATCC 
GACCCCTACT TTGGGTTTGA AGAAGCAAAG AGGAAGTTAC AAGAAAGACC CTGGCTCGTG 
GATTCCTACA GCGAGTGGCT TCAGAGATTA AAGGGGCCCC CTCATAAATG TGCCTTAATT 
TTCGCAGATA ACAGTGGAAT AGACATCATT TTGGGAGTCT TCCCCTTTGT CAGGGAGCTA 
CTCCTTAGAG GGACAGAGGT CATCCTGGCG TGCAACTCAG GCCCCGCCCT GAACGACGTG 
ACCCACAGCG AGTCCCTCAT CGTGGCAGAG CGTATTGCGG GCATGGACCC TGTCGTGCAC 
TCTGCGCTCC AGGAAGAGAG GCTGCTGCTG GTGCAGACGG GCTCCAGCTC CCCGTGCCTC 
GACCTCAGCC GCCTGGATAA GGGGCTGGCC GCACTGGTGC GGGAGCGTGG CGCGGATCTG 
GTGGTCATCG AGGGCATGGG CCGTGCTGTC CACACAAACT ACCACGCAGC CCTGCGCTGC 
GAGAGCCTCA AGCTGGCCGT CATCAAGAAC GCGTGGCTGG CCGAGCGGCT GGGCGGCCGG 
CTCTTCAGCG TCATCTTCAA GTACGAGGTC CCAGCCGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PANK4 ( XM_017001633.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016857122.1 Homo sapiens pantothenate kinase 4 (PANK4), transcript variant X1, mRNA.

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CloneID	OHu90180
Clone ID Related Accession (Same CDS sequence)	XM_017001633.1
Accession Version	XM_017001633.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1881bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	pantothenate kinase 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACGTGCC TGATTAAGGG GTGCAACTTC GTGCTCAAGA ACATCCCCCA TGAGGCCTTC 
GTGTACCAGA AGGATTCCGA CCCTGAGTTC CGGTTCCAGA CCAACCACCC CCACATTTTC 
CCCTATCTTC TTGTCAATAT CGGCTCTGGA GTCTCCATCG TGAAGGTGGA GACGGAGGAC 
AGGTTCGAGT GGGTCGGCGG CAGCTCCATT GGAGGCGGCA CCTTCTGGGG GCTTGGCGCT 
CTGCTCACCA AAACGAAGAA GTTTGACGAG CTCCTGCACC TGGCCTCGAG GGGCCAGCAC 
AGCAATGTGG ACATGCTGGT GCGGGACGTC TACGGCGGCG CCCACCAGAC TCTCGGGCTG 
AGCGGGAACC TCATCGCCAG CAGCTTCGGG AAGTCGGCCA CCGCCGACCA AGAGTTCTCC 
AAAGAAGACA TGGCGAAGAG CCTGCTGCAC ATGATCAGCA ACGACATTGG GCAGCTGGCC 
TGCCTCCACG CACGGCTGCA CAGCCTGGAC CGCGTGTACT TTGGAGGCTT CTTTATCCGG 
GGCCACCCCG TGACCATGCG CACCATCACC TATAGCATCA ACTTCTTCTC CAAGGGGGAA 
GTGCAGGCGC TGTTTCTGAG GCACGAAGGC TACCTGGGAG CCATCGGAGC GTTCCTGAAA 
GGAGCTGAGC AGGACAATCC TAACCAGTAC AGCTGGGGAG AGAACTATGC AGGCAGCTCC 
GGGCTGATGA GTGCATCACC CGAGCTCGGC CCGGCGCAGC GGGCGCGGAG TGGCACTTTT 
GACTTGCTGG AAATGGACCG GCTGGAGAGG CCACTGGTTG ACCTGCCGCT CCTCCTGGAC 
CCGCCCTCCT ACGTGCCCGA CACGGTGGAC CTCACCGATG ACGCTCTGGC CCGAAAATAC 
TGGCTCACCT GCTTTGAGGA GGCCCTGGAC GGGGTAGTGA AGCGCGCAGT GGCGAGCCAG 
CCAGACTCTG TGGATGCAGC CGAGAGGGCG GAGAAGTTCC GGCAGAAGTA CTGGAACAAG 
CTTCAGACCC TGAGGCAGCA GCCCTTCGCC TATGGGACCC TGACCGTGCG CAGCCTGCTG 
GACACCAGGG AGCACTGTCT GAACGAGTTC AACTTCCCGG ATCCCTACTC CAAAGTGAAG 
CAGCGGGAGA ATGGCGTGGC GCTGAGGTGC TTCCCCGGGG TCGTGCGCTC CCTGGACGCG 
CTGGGCTGGG AGGAACGGCA GCTGGCGCTG GTGAAAGGCC TCCTGGCGGG GAATGTCTTC 
GACTGGGGGG CCAAAGCCGT GTCTGCTGTC CTTGAATCCG ACCCCTACTT TGGGTTTGAA 
GAAGCAAAGA GGAAGTTACA AGAAAGACCC TGGCTCGTGG ATTCCTACAG CGAGTGGCTT 
CAGAGATTAA AGGGGCCCCC TCATAAATGT GCCTTAATTT TCGCAGATAA CAGTGGAATA 
GACATCATTT TGGGAGTCTT CCCCTTTGTC AGGGAGCTAC TCCTTAGAGG GACAGAGGTC 
ATCCTGGCGT GCAACTCAGG CCCCGCCCTG AACGACGTGA CCCACAGCGA GTCCCTCATC 
GTGGCAGAGC GTATTGCGGG CATGGACCCT GTCGTGCACT CTGCGCTCCA GGAAGAGAGG 
CTGCTGCTGG TGCAGACGGG CTCCAGCTCC CCGTGCCTCG ACCTCAGCCG CCTGGATAAG 
GGGCTGGCCG CACTGGTGCG GGAGCGTGGC GCGGATCTGG TGGTCATCGA GGGCATGGGC 
CGTGCTGTCC ACACAAACTA CCACGCAGCC CTGCGCTGCG AGAGCCTCAA GCTGGCCGTC 
ATCAAGAACG CGTGGCTGGC CGAGCGGCTG GGCGGCCGGC TCTTCAGCGT CATCTTCAAG 
TACGAGGTCC CAGCCGAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016857122.1
CDS	896..2776
Translation	MTCLIKGCNFVLKNIPHEAFVYQKDSDPEFRFQTNHPHIFPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQEFSKEDMAKSLLHMISNDIGQLACLHARLHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKGAEQDNPNQYSWGENYAGSSGLMSASPELGPAQRARSGTFDLLEMDRLERPLVDLPLLLDPPSYVPDTVDLTDDALARKYWLTCFEEALDGVVKRAVASQPDSVDAAERAEKFRQKYWNKLQTLRQQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQRENGVALRCFPGVVRSLDALGWEERQLALVKGLLAGNVFDWGAKAVSAVLESDPYFGFEEAKRKLQERPWLVDSYSEWLQRLKGPPHKCALIFADNSGIDIILGVFPFVRELLLRGTEVILACNSGPALNDVTHSESLIVAERIAGMDPVVHSALQEERLLLVQTGSSSPCLDLSRLDKGLAALVRERGADLVVIEGMGRAVHTNYHAALRCESLKLAVIKNAWLAERLGGRLFSVIFKYEVPAE

Target ORF information:

RefSeq Version	XM_017001633.1
Organism	Homo sapiens(human)
Definition	Homo sapiens pantothenate kinase 4 (PANK4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017001633.1

ORF Insert Sequence:

ATGACGTGCC TGATTAAGGG GTGCAACTTC GTGCTCAAGA ACATCCCCCA TGAGGCCTTC 
GTGTACCAGA AGGATTCCGA CCCTGAGTTC CGGTTCCAGA CCAACCACCC CCACATTTTC 
CCCTATCTTC TTGTCAATAT CGGCTCTGGA GTCTCCATCG TGAAGGTGGA GACGGAGGAC 
AGGTTCGAGT GGGTCGGCGG CAGCTCCATT GGAGGCGGCA CCTTCTGGGG GCTTGGCGCT 
CTGCTCACCA AAACGAAGAA GTTTGACGAG CTCCTGCACC TGGCCTCGAG GGGCCAGCAC 
AGCAATGTGG ACATGCTGGT GCGGGACGTC TACGGCGGCG CCCACCAGAC TCTCGGGCTG 
AGCGGGAACC TCATCGCCAG CAGCTTCGGG AAGTCGGCCA CCGCCGACCA AGAGTTCTCC 
AAAGAAGACA TGGCGAAGAG CCTGCTGCAC ATGATCAGCA ACGACATTGG GCAGCTGGCC 
TGCCTCCACG CACGGCTGCA CAGCCTGGAC CGCGTGTACT TTGGAGGCTT CTTTATCCGG 
GGCCACCCCG TGACCATGCG CACCATCACC TATAGCATCA ACTTCTTCTC CAAGGGGGAA 
GTGCAGGCGC TGTTTCTGAG GCACGAAGGC TACCTGGGAG CCATCGGAGC GTTCCTGAAA 
GGAGCTGAGC AGGACAATCC TAACCAGTAC AGCTGGGGAG AGAACTATGC AGGCAGCTCC 
GGGCTGATGA GTGCATCACC CGAGCTCGGC CCGGCGCAGC GGGCGCGGAG TGGCACTTTT 
GACTTGCTGG AAATGGACCG GCTGGAGAGG CCACTGGTTG ACCTGCCGCT CCTCCTGGAC 
CCGCCCTCCT ACGTGCCCGA CACGGTGGAC CTCACCGATG ACGCTCTGGC CCGAAAATAC 
TGGCTCACCT GCTTTGAGGA GGCCCTGGAC GGGGTAGTGA AGCGCGCAGT GGCGAGCCAG 
CCAGACTCTG TGGATGCAGC CGAGAGGGCG GAGAAGTTCC GGCAGAAGTA CTGGAACAAG 
CTTCAGACCC TGAGGCAGCA GCCCTTCGCC TATGGGACCC TGACCGTGCG CAGCCTGCTG 
GACACCAGGG AGCACTGTCT GAACGAGTTC AACTTCCCGG ATCCCTACTC CAAAGTGAAG 
CAGCGGGAGA ATGGCGTGGC GCTGAGGTGC TTCCCCGGGG TCGTGCGCTC CCTGGACGCG 
CTGGGCTGGG AGGAACGGCA GCTGGCGCTG GTGAAAGGCC TCCTGGCGGG GAATGTCTTC 
GACTGGGGGG CCAAAGCCGT GTCTGCTGTC CTTGAATCCG ACCCCTACTT TGGGTTTGAA 
GAAGCAAAGA GGAAGTTACA AGAAAGACCC TGGCTCGTGG ATTCCTACAG CGAGTGGCTT 
CAGAGATTAA AGGGGCCCCC TCATAAATGT GCCTTAATTT TCGCAGATAA CAGTGGAATA 
GACATCATTT TGGGAGTCTT CCCCTTTGTC AGGGAGCTAC TCCTTAGAGG GACAGAGGTC 
ATCCTGGCGT GCAACTCAGG CCCCGCCCTG AACGACGTGA CCCACAGCGA GTCCCTCATC 
GTGGCAGAGC GTATTGCGGG CATGGACCCT GTCGTGCACT CTGCGCTCCA GGAAGAGAGG 
CTGCTGCTGG TGCAGACGGG CTCCAGCTCC CCGTGCCTCG ACCTCAGCCG CCTGGATAAG 
GGGCTGGCCG CACTGGTGCG GGAGCGTGGC GCGGATCTGG TGGTCATCGA GGGCATGGGC 
CGTGCTGTCC ACACAAACTA CCACGCAGCC CTGCGCTGCG AGAGCCTCAA GCTGGCCGTC 
ATCAAGAACG CGTGGCTGGC CGAGCGGCTG GGCGGCCGGC TCTTCAGCGT CATCTTCAAG 
TACGAGGTCC CAGCCGAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
PloS one7(12)e51954(2012)
Comuzzie AG,Cole SA,Laston SL,Voruganti VS,Haack K,Gibbs RA,Butte NF

High glucose upregulates pantothenate kinase 4 (PanK4) and thus affects M2-type pyruvate kinase (Pkm2).
Molecular and cellular biochemistry277(1-2)117-25(2005 Sep)
Li Y,Chang Y,Zhang L,Feng Q,Liu Z,Zhang Y,Zuo J,Meng Y,Fang F

A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome.
Nature genetics28(4)345-9(2001 Aug)
Zhou B,Westaway SK,Levinson B,Johnson MA,Gitschier J,Hayflick SJ

Coenzyme A metabolism.
The American journal of physiology248(1 Pt 1)E1-9(1985 Jan)
Robishaw JD,Neely JR

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PANK4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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