Gene Symbol | PHF1 |
Entrez Gene ID | 5252 |
Full Name | PHD finger protein 1 |
Synonyms | MTF2L2,PCL1,PHF2,TDRD19C,hPHF1 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a Polycomb group protein. The protein is a component of a histone H3 lysine-27 (H3K27)-specific methyltransferase complex, and functions in transcriptional repression of homeotic genes. The protein is also recruited to double-strand breaks, and reduced protein levels results in X-ray sensitivity and increased homologous recombination. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]. |
Disorder MIM: |